Abstract: Methods for training a model for use in monitoring a health parameter in a person are disclosed. In an embodiment, a method involves monitoring a blood pressure of a person using a control blood pressure monitoring system, receiving control data that corresponds to the monitoring using the control blood pressure monitoring system, receiving stepped frequency scanning data that corresponds to radio waves that have reflected from blood in a blood vessel of the person, wherein the stepped frequency scanning data is collected through multiple receive antennas over a range of frequencies, generating training data by combining the control data with the stepped frequency scanning data in a time synchronous manner, and training a model using the training data to produce a trained model, wherein the trained model correlates stepped frequency scanning data to values that are indicative of a blood pressure of a person.

Abstract: A bio-signal measuring apparatus includes a first electrode, a second electrode, a third electrode, a fourth electrode, and a first circuit network and a second circuit network, each of the first circuit network and the second circuit network includes one or more resistances. The bio-signal measuring apparatus further includes an impedance measurer configured to measure a first impedance of the first circuit network in a first correction mode, measure a second impedance of the second circuit network in a second correction mode, measure a third impedance of an object in a first measurement mode, using the first electrode, the second electrode, the third electrode, and the fourth electrode, and measure a fourth impedance of the object in a second measurement mode, using the first electrode, the second electrode, the third electrode, and the fourth electrode.

Abstract: There is provided a system (100) and method for determining a water or lipid level of skin. The system (100) comprises at least two electrodes (108) suitable for contacting skin, and a signal generator (106) configured to generate an electrical signal at a frequency across the at least two electrodes (108). The system (100) is configured to measure a conductivity between the at least two electrodes (108). The system (100) is further configured to determine a water or lipid level of skin based on the measured conductivity and the frequency of the electrical signal.

Abstract: A method includes transmitting electrical signals between one or more pairs of body-surface electrodes attached to a body of a patient. Electrical potentials resulting from the transmitted electrical signals are acquired by an outer-facing electrode and an inner-facing electrode of a medical probe inserted in an organ of the patient. A proximity of the medical probe to surface tissue of the organ is estimated based on the electrical potentials acquired by the outer-facing electrode. A position of the medical probe within the organ is estimated based on the electrical potentials acquired by the inner-facing electrode.

Abstract: Systems and methods for measurement of end tidal carbon dioxide, including a device having a body and a tubular gas line. The body is adapted to be attached to a patient airway and has a first gas line securing portion which has an aperture through it and is adapted to secure the gas line to the body. The tubular gas line is secured in the aperture. The tubular gas line has a proximal portion extending from a proximal end of the aperture and has a proximal end which is adapted to be connected to an end tidal CO2 monitor. The tubular gas line also has a distal portion extending from a distal end of the aperture and having a distal end which provides an inlet for end tidal CO2 exhaled by a patient.

Abstract: The present disclosure describes a system for metabolic monitoring comprising: collecting exhaled gas from nasal airways of a subject; a mixing chamber for receiving a portion of the exhaled gas; a plurality of sensors for outputting signals related to gas parameters related to inhaled gas and exhaled gas during one or more breaths; and processors configured to determine a flow rate of gas in the interface appliance; determine pressure changes near the mouth of the subject to detect mouth breathing of the subject; determine concentration measurements of O2 and CO2 of the portion of the exhaled gas in the mixing chamber, and discard concentration measurements corresponding to mouth breathing; determine a rate of oxygen consumption VO2 and a carbon dioxide production VCO2 of the subject based on the determined flow rate, the CO2 concentration, and the determined O2 concentration.

Abstract: The present invention relates to an automated method of determining a kinetic state of a person. The method obtains accelerometer data from an accelerometer worn on an extremity of the person and processes the accelerometer data to determine a measure for the kinetic state. The present invention further relates to a device for determining a kinetic state of a person. The device comprises a processor configured to process data obtained from an accelerometer worn on an extremity of the person and to determine from the data a measure for the kinetic state. In the method and system the kinetic state is at least one of bradykinesia, dyskinesia, and hyperkinesia.

Abstract: This disclosure relates generally to health monitoring and assessment systems, and more particularly to perform postural stability assessment of a user and quantify the assessed postural stability. In an embodiment, the system, by monitoring specific actions (which are part of certain tests done for the postural stability assessment) being performed by a user, collects inputs which are then processed to determine SLS duration, the body joint vibration, and the body sway area of the user, while performing the tests. By processing the SLS duration, the body joint vibration, and the body sway area together, a postural stability index score for the user is determined, and based on this score, postural stability assessment for the user is performed.

Abstract: The invention provides systems for handling biofluids including the transport, capture, collection, storage, sensing, and/or evaluation of biofluids released by tissue. Systems of some aspects provide a versatile platform for characterization of a broad range of physical and/or chemical biofluid attributes in real time and over clinically relevant timeframes. Systems of some aspects provide for collection and/or analysis of biofluids from conformal, watertight tissue interfaces over time intervals allowing for quantitative temporal and/or volumetric characterization of biofluid release, such as release rates and release volumes.

Abstract: Methods, devices and system for determining fasting glucose level information and post-prandial glucose level information for diagnosing pre-diabetic and diabetic conditions based on monitored glucose measurements are provided.

Abstract: An apparatus for estimating a concentration of an analyte may include a spectrum acquisition device configured to acquire a first in vivo spectrum of an object, and a processor configured to estimate the concentration of the analyte using the first in vivo spectrum and a concentration estimation model that is generated based on a second in vivo spectrum measured during a timeframe in which the concentration of the analyte in the object is substantially constant, and update the concentration estimation model based on the first in vivo spectrum and the estimated concentration of the analyte.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.

Abstract: An optoelectronic sensor module and a method for producing an optoelectronic sensor module are disclosed. In an embodiment an optoelectronic sensor module includes a first semiconductor transmitter chip configured to emit radiation of a first wavelength, a second semiconductor transmitter chip configured to emit radiation of a second wavelength different from the first wavelength, a semiconductor detector chip configured to detect the radiation of the first and second wavelengths, and a first potting body being opaque to the radiation of the first and the second wavelength, wherein the first potting body directly covers side surfaces of the chips and mechanically connects the chips located in a common plane to one another, wherein a distance between the chips is less than or equal to twice an average diagonal length of the chips, and wherein the sensor module is adapted to rest against a body part to be examined.

Abstract: Aspects relate to systems and methods for determining actor status according to behavioral phenomena. An exemplary system includes an eye sensor configured to detect an eye parameter as a function of an eye phenomenon, a speech sensor configured to detect a speech parameter as a function of a speech phenomenon, and a processor in communication with the eye sensor and the speech sensor; the processor is configured to receive the eye parameter and the speech parameter, determine an eye pattern as a function of the eye parameter, determine a speech pattern as a function of the speech parameter, and correlate one or more of the eye pattern and the speech pattern to a cognitive status.

Abstract: Systems and methods for lean muscle mass monitoring of patients and for identifying and treating at least one of Cachexia or Sarcopenia are disclosed. The system may include a dynamometer provided to patients, the dynamometer being configured to perform remote monitoring. The dynamometer may be used and data may be collected by patients without the supervision of a healthcare professional. Using the collected data, lean muscle mass may be tracked over time, to provide fast and accurate assessment of conditions. Using such an assessment, early treatment options can be targeted to patients to avoid progression into various disease states, for examples, more severe states of at least one of Cachexia or Sarcopenia.

Abstract: A reliable technology for determining the masticatory side of the user is provided. First and second electromyographic waveforms respectively originating from left and right muscles related to masticatory actions of a user are acquired; a coefficient of correlation between pieces of information respectively extracted from the first and the second electromyographic waveforms is calculated as a first feature value; a second feature value is calculated from a power spectrum obtained by performing frequency analysis on the first electromyographic waveform; a third feature value is calculated from a power spectrum obtained by performing frequency analysis on the second electromyographic waveform; a learning model is generated by associating the first, second, and third feature values with a plurality of labels; and the masticatory side of the user is determined based on first, second, and third feature values calculated from a newly acquired electromyographic waveform and the learning model.

Abstract: Methods and systems for conditioning a signal indicative of electrosurgical unit activity are described. A hardware circuit acquires AC current from an electrosurgical unit on patient isolated circuitry and conditions the signal in either of two alternate processing methods. The processed signal is routed as input to an analog to digital converter circuit. A method for determining saturation on referential inputs and recovering inputs to an unsaturated state is also described.

Abstract: A bioelectrode includes a conductive rubber electrode and a silver coating layer provided on the conductive rubber electrode and containing a silicone rubber and silver particles. The silver coating layer contains a modified silicone and contains ions for ion conduction among the silver particles.

Abstract: A user-specific model of muscular activity can be used to control an external device based on muscular activity within a limb of a user. The user-specific model of muscular activity can include single movements and corresponding one or more primary muscle patterns. New single movements can be added to the user-specific model of muscular activity can be by a system that includes a processor by receiving user-specific EMG signals (including one or more EMG patterns that indicate a single movement); decomposing the user-specific EMG signals into the one or more EMG patterns in EMG feature space that indicate the single movement; and updating the user-specific model of muscular activity to include the single movement and corresponding one or more primary muscle patterns based on the one or more EMG patterns in EMG feature space.

Abstract: A method for generating a filtered EMG signal includes obtaining a combined signal, wherein the combined signal comprises an ECG signal and an EMG signal. A first high pass filter is applied to the combined signal and an ECG model signal is generated, based on the high pass filtered combined signal. The method further includes, generating a partially filtered EMG signal by subtracting the ECG model from the high pass filtered combined signal. A second high pass filter is then applied to the partially filtered EMG signal to generate a second EMG signal and to the ECG model signal to generate a second ECG model signal. A filtered EMG signal is generated based on the second EMG signal and the second ECG model by way of a gating technique.

Abstract: Systems and methods for facilitating display of cardiac information based on sensed electrical signals include a processing unit configured to receive a set of electrical signals; receive an indication of a measurement location corresponding to each electrical signal of the set of electrical signals; and generate an activation histogram corresponding to the set of electrical signals. Systems and methods disclosed herein may be configured to automatically identify activation histograms exhibiting split characteristics, and to facilitate presentation, on a display device, of a cardiac map including highlighted regions corresponding to the identified activation histograms.

Abstract: Techniques are disclosed for automatically calibrating a reference orientation of an implantable medical device (IMD) within a patient. In one example, sensors of an IMD sense a plurality of orientation vectors of the IMD with respect to a gravitational field. Processing circuitry of the IMD processes the plurality of orientation vectors to identify an upright vector that corresponds to an upright posture of the patient. The processing circuitry classifies the plurality of orientation vectors with respect to the upright vector to define a sagittal plane of the patient and a transverse plane of the patient. The processing circuitry determines, based on the upright vector, the sagittal plane, and the transverse plane, a reference orientation of the IMD within the patient. As the orientation of the IMD within the patient changes over time, the processing circuitry may recalibrate its reference orientation and accurately detect a posture of the patient.

Abstract: A method for analyzing arrhythmia in real time and an electrocardiogram monitoring device is disclosed. The method for analyzing arrhythmia in real time includes: acquiring a QRS template set currently used for arrhythmia analysis; determining whether each QRS template in the QRS template set is reliable; displaying information of a QRS template when the QRS template set contains an unreliable QRS template; determining the QRS template set according to an operation performed by a user on the information of the QRS template; and acquiring real-time electrocardiogram data, performing arrhythmia analysis on the real-time electrocardiogram data by using a determined QRS template set, and outputting an arrhythmia analysis result of the real-time electrocardiogram data in real time. The method for analyzing arrhythmia in real time may achieve the correction of a template of a special waveform by means of editing a currently created QRS template.

Abstract: A method, computer program, and computer system for detecting and classifying atrial fibrillation by receiving data corresponding to an electrocardiogram (ECG) associated with a patient, extracting RR intervals from the received ECG data, determining previous RR intervals for each of the extracted RR intervals and aggregating features associated with the RR intervals and the previous RR intervals. Patterns associated with the aggregated features are classified, and the computer may determine that a sample of the ECG data corresponding to one or more of the classified patterns contains a pattern associated with atrial fibrillation.

Abstract: A method and device allowing a physiological signal, typically representative of brain activity, to be transcribed in the form of sensory signals perceptible to a human user, typically acoustic signals is provided. For this purpose, a physiological signal is acquired and then analysed in such a way as to detect therein patterns that are then parameterised in the time domain. One or more parameters of these patterns are used to determine one or more parameters of the generated sensory signals and/or to determine one or more parameters of temporal envelopes used to modulate the sensory signals. This method and device can be applied, in particular, to neuro-acoustic transduction.

Abstract: A technology is described for determining an intended movement from neuromuscular signals. An example method (800) includes receiving electromyography (EMG) data corresponding to single-ended channels of an electrode array (810), where EMG signals are detected by electrodes comprising the single-ended channels of the electrode array and the EMG signals are converted to the EMG data. Determining differential channel pairs for the single-ended channels of the electrode array (820) and extracting feature data from the EMG data of the differential channel pairs (830). Thereafter a feature data set is selected from the feature data of the differential channel pairs (840) and the feature data set is input to a decode model configured to correlate the feature data set to an intended movement (850). Decode output is received from the decode model indicating the intended movement (860) and the decode output is provided to a device (870).

Abstract: Orthopedic device or implants are provided, comprising an orthopedic device or implant and a sensor.

Abstract: Devices that take a novel approach to parameter measurement and output or transmission of signals, medicine, heat, etc. These devices are compact, versatile, relatively inexpensive, and require minimal training to be effectively used. These devices can be configured as interchangeable devices incorporated into a wearable article or device.

Abstract: There is provided a system (100) and method for determining a water or lipid level of skin. The system (100) comprises at least two electrodes (108) suitable for contacting skin, and a signal generator (106) configured to generate an electrical signal at a frequency across the at least two electrodes (108). The system (100) is configured to measure a permittivity between the at least two electrodes (108). The system (100) is further configured to determine a water or lipid level of skin based on the measured permittivity and the frequency of the electrical signal.

Abstract: The present invention relates to a system (1) for estimating cardiovascular fitness of a person, comprising a heart rate monitor (10) for acquiring a heart rate signal including information about the heart rate of the person, an activity monitor (20) for acquiring an activity signal indicative of physical activity of the person, a classifier (30) for classifying the activity of the person based on the acquired activity signal, a selector (40) for selecting one or more heart rate features obtained from the acquired heart rate signal based on the acquired heart rate signal and the classification of the activity for use in an estimation of the cardiovascular fitness of the person, and an estimator (50) for estimating the cardiovascular fitness of the person based on the one or more selected heart rate features.

Abstract: Disclosed herein is a non-invasive system for determining tissue composition. The system comprises an imaging system with a non-invasive probe, a signal analyzer, and a correlation processor. The probe includes active imaging components for emitting energy and collecting imaging data including reflected signals from an object of interest. The signal analyzer analyzes the imaging data and determines one or more signal properties from the reflected signals. The correlation processor then associates the one or more signal properties to pre-determined tissue signal properties of different tissue components through a pattern recognition technique wherein the pre-determined tissue signal properties are embodied in a database, and identifies a tissue component of the object based on the pattern recognition technique.

Abstract: A route selection assistance system enabling easy selection of a route of a living body lumen for delivering a medical instrument to a site within a living body via the living body lumen, a recording medium on which a route selection assistance program is recorded, and a route selection assistance method are disclosed. The route selection assistance system includes: a receiving section configured to receive an input of site information specifying a target site; an image obtaining section configured to obtain image information on a living body of a target patient; a route extracting section configured to extract a plurality of routes of a living body lumen; a ranking assigning section configured to assign rankings to the plurality of routes according to ease of delivery of the medical instrument and patient scores determined according to magnitude of a burden imposed on the target patient.

Abstract: Embodiments of the present disclosure relate to monitoring one or more physiological parameters of a subject using a multilayer wearable device. In an embodiment, a multilayer wearable device is configured to be attached to a subject. The multilayer wearable device comprises a substrate having multiple layers including a first portion connected to a second portion. The first portion has a first side and a second, opposite side. And the second portion has a first side and a second, opposite side. The first side of the first portion is configured to be attached to the subject and the second portion is arranged on top of the first portion such that the first side of the second portion is disposed adjacent the second side of the first portion. And, the wearable device includes one or more electrical components configured to sense a physiological parameter of the subject.

Abstract: An apparatus for monitoring a sleep parameter of a user includes an adhesive pad configured to conform to a surface of the user and a flexible element coupled to the adhesive pad. The flexible element includes a conductive fabric, and exhibits a modified electrical property in response to an applied force. The apparatus also includes a power source electrically coupled to the flexible element, and an electrical circuit electrically coupled to the power source and the flexible conductive element. The electrical circuit is configured to detect, during use, a change in an electrical property of the flexible element.

Abstract: The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.

Abstract: The present it relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.

Abstract: A sleep study system comprises a set of sensors for monitoring physiological parameters of a subject during sleep as part of a sleep study and for monitoring the sleep stage of the subject. It is determined if intervention to the subject is needed for maintenance or repair to the sleep study system. If so, a time to perform the intervention is also derived based on the sleep stage of the subject, in particular so as to be least disruptive to the subject.

Abstract: The physical and physiological events at one end of an Abreu Brain Thermal Tunnel (ABTT) are reproduced at the opposite end. Thus, the ABTT enables the direct transfer of outputs from a brain core to an ABTT terminus without significant barriers. Accordingly, apparatuses, systems, devices, mechanisms, and methods use the ABTT terminus and the ABTT to measure the temperature of the brain core.

Abstract: Medical devices and related systems and methods are provided. A method of providing a notification pertaining to a physiological condition using a translation model involves identifying an error metric associated with an input variable associated with the translation model, determining a reference output of the translation model by providing reference values for the input variable to the translation model, generating modulated values for the input variable based on the reference values using the error metric, determining a simulated output of the translation model by providing the modulated values for the input variable to the translation model, and updating the translation model to reduce a weighting associated with the input variable when a difference between the simulated output and the reference output is greater than a threshold.

Abstract: A system for collecting data for assessment of cardiovascular function includes a plurality of monitoring devices coupled to different respective body parts. Each monitoring device is configured to measure a respective signal at the respective body part in response to cardiovascular activity. The respective signal includes a cardiovascular component attributable to the cardiovascular activity and an artifact component not attributable to the cardiovascular activity. When the monitoring devices measure the respective signals simultaneously over a same time period, the cardiovascular components are correlated, and the artifact components are not correlated.

Abstract: A plurality of sets of simulated optical inputs that is simulated to travel through an animal model of tissue, thereby generating simulated light transmission data, and corresponding oximetry vales may be used to train a simulated fetal oximetry model to predict, or calculate, oximetry values for subsequently received sets of simulated light transmission data. The simulated fetal oximetry model may be adapted to train an in vivo fetal oximetry model that may be configured to predict, or calculate, fetal oximetry values for subsequently received sets of light transmission data received from an in vivo study of a pregnant mammal and her fetus.

Abstract: A method and system are devised for quickly detecting an abnormal concentration of potassium ions in blood from an electrocardiogram. The system includes at least one vector-converting device that includes a processor, a transmitter, at least one memory and at least one storage unit. The at least one storage includes a model data module and a predicting and converting module. The model data module includes data of a model of the concentration of potassium in the blood. The model of the concentration of potassium in the blood includes at least one reference electrocardiogram and corresponding reference data of the concentration of potassium in the blood. The predicting and converting module converts an electrocardiogram into a corresponding predicted concentration of potassium in the blood according to the reference concentration of potassium in blood. The vector conversions device is connected to at least one electrocardiogram generator and at least one monitor.

Abstract: The present disclosure provides systems and methods for calibrating medical devices and processing physiological measurements using a medical device management system. As an example, the medical device can be a handheld glucometer configured for invasive testing and non-invasive testing of physiological parameters of a patient.

Abstract: The present invention provides a method for detecting events in an input signal. The method uses a volatile resistive switching component to detect the events in the input signal. The method comprising identifying the events based on sampling an output from the resistive switching component.

Abstract: A multi-parameter patient monitoring device rack can dock a plurality of patient monitor modules and can communicate with a separate display unit. A signal processing unit can be incorporated into the device rack. A graphics processing unit can be attached to the display unit. The device rack and the graphic display unit can have improved heat dissipation and drip-proof features. The multi-parameter patient monitoring device rack can provide interchangeability and versatility to a multi-parameter patient monitoring system by allowing use of different display units and monitoring of different combinations of parameters. A dual-use patient monitor module can have its own display unit configured for displaying one or more parameters when used as a stand-alone device, and can be docked into the device rack when a handle on the module is folded down.

Abstract: A method and system for determining a PET image of the scan volume based on one or more PET sub-images is provided. The method may include determining a scan volume of a subject supported by a scan table; dividing the scan volume into one or more scan regions; for each scan region of the one or more scan regions, determining whether there is a physiological motion in the scan region; generating, based on a result of the determination, a PET sub-image of the scan region based on first PET data of the scan region acquired in a first mode or based, at least in part, on second PET data of the scan region acquired in a second mode; and generating a PET image of the scan volume based on one or more PET sub-images.

Abstract: An electromagnetic tracking system including a patient support element and an electromagnetic field generator. The patient support element is superposed relative to the electromagnetic field generator, and the electromagnetic field generator is selectively moveable relative to the patient support element.

Abstract: A breast compression paddle has two sidewalls, each having an upper edge. Spanning the two side walls is a leading wall which also has an upper edge and is disposed distal from a bracket that is connected to a compression arm. Foam is secured to a substrate which is movably secured to the bracket and the rigid frame between a first position and a second position. In the first position, portions of the substrate and foam are disposed above the upper edges of all three walls. In the second position, the substrate and all of the foam is disposed below the upper edges of all three walls.

Abstract: Provided is a method of generating a virtual x-ray image, the method including: obtaining a 3-dimensional (3D) image of a patient; determining a projection direction of the 3D image in consideration of a position relationship between an x-ray source of an x-ray device and the patient; and generating a virtual x-ray image by projecting the 3D image on a 2D plane in the determined projection direction.

Abstract: Systems and methods for digital X-ray imaging are disclosed. An example portable X-ray scanner includes: an X-ray detector configured to generate digital images based on incident X-ray radiation; an X-ray tube configured to output X-ray radiation; a computing device configured to control the X-ray tube, receive the digital images from the X-ray detector, and output the digital images to a display device; a power supply configured to provide power to the X-ray tube, the X-ray detector, and the computing device; and a frame configured to: hold the X-ray detector, the computing device, and the power supply; and hold the X-ray tube such that the X-ray tube directs the X-ray radiation to the X-ray detector.