Abstract: An oscillator for density measurement of a liquid, including a counter mass and a container for the liquid. The oscillator is made of metal and the container has two identical resonator tubes, which are clamped into the counter mass in parallel to each other, and a connecting tube connecting the resonator tubes. The resonator tubes can be set into a resonance oscillation in which a common centre of gravity of the resonator tubes remains at rest during the resonance oscillation. The oscillator also includes a web located between the counter mass and the connecting tube, which web spaces the resonator tubes from each other in such a way that the lengths (L) of the resonator tubes enclosed between the counter mass and the web can be set into a diametrically opposite oscillation on the basis of which the density of the liquid located in the oscillator can be determined.

Abstract: The invention is directed to an automated Marsh funnel and Marsh funnel apparatus or system, and an automated method for measuring the Marsh funnel time and density of drilling muds and calculating other rheological properties from Marsh funnel time and mud weight. The system measures and reports rheological properties of drilling muds in real time and faster, more conveniently, and more accurately than conventional manual methods.

Abstract: The present invention relates to a device for measuring rheological properties of a high-viscosity material and a measurement method thereof in which, while a discharger of the present invention is completely blocked, a change in pressure of the high-viscosity material due to a change in the number of rotations of a first screw is measured, thus having an advantage of being able to precisely and reproducibly measure the viscosity.

Abstract: The present invention provides an adjustment device for a flexible wall surface suitable for droplet impact, which includes a base, a staybolt, an experiment substrate and the wall surface to be tested, wherein the periphery of the wall surface to be tested is fixed to the upper surface of the experiment substrate by an adhesion agent and the inclination angle of the wall surface to be tested is adjusted by adjusting the left two staybolts and right two staybolts on the experiment substrate to different heights; and a plurality of through holes are uniformly formed on the experiment substrate and provided therein with wall surface adjusting bolts used to abut against and apply force to the wall surface to be tested, so as to allow the wall surface to be tested to present a desired curved shape.

Abstract: A quasi-soft catcher, a quasi-soft capture device, and a method for using the same are provided. The quasi-soft catcher includes a base and a plurality of protruding structures for capturing at least one target biological particle from a specimen. The protruding structures are regularly arranged on a board surface of the base. Each of the protruding structures includes an outer portion configured to touch the at least one target biological particle and an inner portion that is connected between the board surface and the outer portion, and a structural strength of the inner portion is less than that of the outer portion. The board surface has an interspace region arranged outside of the protruding portions, and the interspace region occupies 20-80% of the board surface.

Abstract: A test piece holder for coalbed fracturing comprises a pressure chamber, first sliding rods, second sliding rods, third sliding rods, fourth sliding rods, fifth sliding rods, oil cylinders and a sealing ring, upper and lower ends of a test piece are both provided with an electrode needle and a gas-guide and liquid-guide conducting bolt, the gas-guide and liquid-guide conducting bolt has a hollow rod structure, an inside end of the gas-guide and liquid-guide conducting bolt located above is communicated with a water-gas channel and an outside end of the gas-guide and liquid-guide conducting bolt located above is a water-gas outlet, an inside end of the gas-guide and liquid-guide conducting bolt located below is communicated with the water-gas channel and an outside end of the gas-guide and liquid-guide conducting bolt located below is respectively provided with a gas inlet and a water inlet.

Abstract: The invention relates to methods and devices for analysis of samples using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The invention provides methods and devices in which individual ablation plumes are distinctively captured and transferred to the ICP, followed by analysis by mass cytometry.

Abstract: A method for inverting aerosol components using a LiDAR ratio and a depolarization ratio, includes: S1. identifying sand dust, a spherical aerosol and a mixture of the sand dust and the spherical aerosol based on a depolarization ratio; S2. calculating a proportion of the sand dust in the mixture of the sand dust and the spherical aerosol; and S3. identifying soot and a water-soluble aerosol in the spherical aerosol based on a LiDAR ratio. In the present disclosure, only a wavelength with a polarization channel is needed, to identify the aerosol components, achieving high accuracy with low detection costs.

Abstract: A high-throughput optofluidic device for detecting fluorescent droplets is disclosed. The device uses time-domain encoded optofluidics to detect a high rate of droplets passing through parallel microfluidic channels. A light source modulated with a minimally correlating maximum length sequences is used to illuminate the droplets as they pass through the microfluidic device. By correlating the resulting signal with the expected pattern, each pattern formed by passing droplets can be resolved to identify individual droplets.

Abstract: An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector.

Abstract: The present application concerns in-situ intrusive probe systems and methods. The probe systems described herein can be installed flush to a hydrocarbon containing structure, such as a pipeline, vessel, or other piping system carrying crude, gas or sour products. The probe systems include hydrogen induced cracking (HIC)-resistant microstructure such that as atomic hydrogen permeates the probe surface, the probe captures recombined hydrogen gas. The pressure of the resultant hydrogen gas buildup is measured and predictions as to the HIC activity of that area can be made.

Abstract: A method for evaluating a structure is disclosed, the structure including a base material containing at least one kind of metal selected from the group consisting of hydrogen storage metals and hydrogen storage alloys, an intermediate layer provided on the base material and stacked alternately with a first layer containing low work function substances relatively lower in work function than the metal and a second layer containing the metal, and a surface layer provided on the intermediate layer and containing the metal, wherein the method includes measuring a change in polarization between incident light and reflected light by irradiating the surface layer with light, while holding the structure at a predetermined temperature, and comparing a measurement value of the change in polarization with a threshold of a change in polarization of a structure prepared in advance and evaluating a soundness of the structure based on comparison results.

Abstract: Systems for biological sensing that include, in one implementation, a sensor, a filter, a pump, and a flow channel. The sensor is configured to test a gas sample. The sensor includes an optical cavity. The filter is configured to filter the gas sample. The flow channel is formed by at least the optical cavity, the filter, and the pump. The pump is configured to generate a negative pressure differential inside the flow channel.

Abstract: The present disclosure relates to techniques for deformulating the spectra of arbitrary compound formulations such as polymer formulations into their chemical components. Particularly, aspects of the present disclosure are directed to obtaining an initial set of spectra for a plurality of samples comprising pure samples and composite samples, constructing a basis set of spectra for a plurality of pure samples based on the initial set of spectra, and providing or outputting the basis set of spectrum. The basis set of spectra is constructed in an iterative process that attempts to decompose, using a decomposition algorithm or model, the spectrum from the initial set of spectra in order to differentiate the pure samples from the composite samples. The basis set of spectra may then be used to deduce the composition of a material from a spectrogram.

Abstract: A concentration measuring device 100 comprises: a measurement cell 4 having a flow path, a light source 1, a photodetector 7 for detecting light emitted from the measurement cell, and an arithmetic circuit 8 for calculating light absorbance and concentration of a fluid to be measured on the basis of an output of the photodetector, the measurement cell includes a cell body, a window portion 3 fixed to the cell body so as to contact the flow path, and a reflective member 5 for reflecting light incident on the measurement cell through the window portion, the window portion is fixed to the cell body 40 by a window holding member 30 via a gasket 15, an annular sealing protrusion 15a is provided on a first surface of the gasket for supporting the window portion, and an annular sealing protrusion 42a is also provided on a support surface 42 of the cell body for supporting the second surface opposite to the first surface of the gasket.

Abstract: An interference image acquisition apparatus includes a light source, a beam splitter, a second reflection mirror, an imager, and a first reflection mirror. A cell is placed on one side of a transparent material, and the first reflection mirror is placed on the other side of the transparent material. In a two-beam interferometer, an optical path difference between an optical path length of a first light beam reflected by the first reflection mirror and an optical path length of a second light beam reflected by the second reflection mirror is set to a coherence length of light output from the light source or less. The imager acquires an interference image in a state in which the cell is placed at a position conjugate to an imaging plane in a first optical system between the imaging plane and the first reflection mirror.

Abstract: A wood stove monitoring and control device can include a mounting flange mountable to a chimney exhaust pipe of a wood stove. The device can include a ring removably mountable on top of the mounting flange, where the flange is suitably positioned vertically along the exhaust pipe so that the ring is positioned at least partially above an end of the exhaust pipe. The device includes an optical beam source disposed on the ring, and which generates and outputs an optical beam. The device includes an optical sensor positioned on the ring opposite the optical beam source to detect the optical beam output by the optical beam source as the optical beam passes through smoke exhausted by the wood stove through the exhaust pipe. The device can include a temperature probe disposed on the ring to measure a temperature of heat exhausted by the wood stove through the exhaust pipe.

Abstract: Provided herein are devices, systems, and methods for characterizing a biological sample in vivo or ex vivo in real-time using time-resolved spectroscopy. A light source generates a light pulse or continuous light wave and excites the biological sample, inducing a responsive fluorescent signal. A demultiplexer splits the signal into spectral bands and a time delay is applied to the spectral bands so as to capture data with a detector from multiple spectral bands from a single excitation pulse. The biological sample is characterized by analyzing the fluorescence intensity magnitude and/or decay of the spectral bands. The sample may comprise one or more exogenous or endogenous fluorophore. The device may be a two-piece probe with a detachable, disposable distal end. The systems may combine fluorescence spectroscopy with other optical spectroscopy or imaging modalities. The light pulse may be focused at a single focal point or scanned or patterned across an area.

Abstract: A biosensor is provided. The biosensor includes a substrate, photodiodes, pixelated filters, an excitation light rejection layer and an immobilization layer. The substrate has pixels. The photodiodes are disposed in the substrate and correspond to one of the pixels, respectively. The pixelated filters are disposed on the substrate. The excitation light rejection layer is disposed on the pixelated filter. The immobilization layer is disposed on the excitation light rejection layer.

Abstract: A fluorescence imaging device includes a display unit that displays an operation screen receiving an operation input, and the display unit displays a setting operation screen including a parameter setting field in which a parameter relating to blue shift correction for correcting shade of a sample image caused by a difference in an incidence angle of fluorescence emitted from each sample at each position where the fluorescence is incident on an optical filter is to be set.

Abstract: A sample observation device includes an irradiation unit that irradiates a sample with planar light, a scanning unit that scans the sample in one direction with respect to an irradiation surface of the planar light, an image formation unit that forms images of fluorescent light and scattered light from the sample, an imaging unit that outputs first image data based on a light image of the fluorescent light and second image data based on a light image of the scattered light, an image processing unit that generates a fluorescent light image on the basis of a plurality of pieces of first image data and generates a scattered light image on the basis of a plurality of pieces of second image data, and an analysis unit that specifies an area in which there is the sample in the fluorescent light image on the basis of the scattered light image, and sets an analysis area in the fluorescent light image on the basis of the area in which there is the sample.

Abstract: Provided herein is an apparatus for assessing a fluorescence characteristic of a gemstone. The apparatus comprises an optically opaque platform for supporting a gemstone to be assessed, one or more light source to provide uniform UV and non-UV illumination, an image capturing component, and a telecentric lens positioned to provide fluorescent images of the illuminated gemstone to the image capturing component. Also provided are methods of fluorescence analysis based on images collected using such an apparatus.

Abstract: Optical device for optical fluorescence microscopy, comprising a spatial modulator (1), a microscope objective (2), a beamsplitter (3) and a camera (4), wherein the beamsplitter (3) is placed between the spatial modulator (1) and the microscope objective (2), wherein the beamsplitter (3) is placed between the camera (4) and the microscope objective (2), and wherein a prism (5) is placed between the beamsplitter (3) and the camera (4).

Abstract: In a fluorescent in-situ hybridization imaging system performs, as nested loops, the following: (1) a valve sequentially couples a flow cell to a plurality of different reagent sources to expose the sample to a plurality of different reagents, (2) for each reagent of the plurality of different reagents, a motor sequentially positions the fluorescence microscope relative to sample at a plurality of different fields of view, (3) for each field of view of the plurality of different fields of view, a variable frequency excitation light source sequentially emits a plurality of different wavelengths, (4) for each wavelength of the plurality of different wavelengths, an actuator sequentially positions the fluorescence microscope relative to sample at a plurality of different vertical heights, and (5) for each vertical height of the plurality of different vertical heights, an image is obtained.

Abstract: Embodiments of the present disclosure provide plasmonic structures, methods of making plasmonic structures, and the like.

Abstract: This invention is in the field of medical devices. Specifically, the present invention provides fluidic systems having a plurality of reaction sites surrounded by optical barriers to reduce the amount of optical cross-talk between signals detected from various reaction sites. The invention also provides a method of manufacturing fluidic systems and methods of using the systems.

Abstract: [Problem] When the inclination of an object surface reaches or exceeds a certain level, direct light consisting of a specularly reflected light component leaves the range of the solid observation angle formed by the observation optical system, and it becomes difficult to continuously and quantitatively obtain the surface shape of the object surface.

Abstract: An analysis method for detecting an amount of a substance by irradiating an analysis chip containing the substance and detecting a quantity of light output from the analysis chip. The analysis method including irradiating an incident surface of the analysis chip and another surface adjacent to the incident surface with detection light while changing a relative position of the detection light with respect to the analysis chip, detecting reflected light from the incident surface of the analysis chip, and acquiring information on a position of the analysis chip from a relationship between a quantity of the reflected light detected and the relative position. The analysis method determines if the analysis chip is abnormal when a quantity of target reflected light is equal to or lower than a predetermined light quantity.

Abstract: A process fluid temperature calculation system includes a first temperature sensor disposed to measure an external temperature of a process fluid conduit. The process fluid temperature calculation system has a stem portion having a known thermal impedance. A second temperature sensor is spaced from the first temperature sensor by the stem portion. Measurement circuitry is coupled to the first and second temperature sensors. A microprocessor is coupled to the measurement circuitry to receive temperature information from the measurement circuitry and to provide an estimate of temperature of process fluid within the process fluid conduit using a heat flux calculation.

Abstract: A sensor system for collecting data regarding sub-surface material characteristics may include a multitude of sensor nodes, a data gateway, and a controller. Each sensor node may include a power supply and a communication device and the multitude of sensor nodes may include sensors distributed between underground sensor nodes and/or partially-exposed sensor nodes to collect data regarding sub-surface material characteristics. The data gateway may be coupled with any combination of the sensor nodes through wireless transmission data pathways and may receive and store at least some of the data collected by the one or more sensors. The controller may receive the data generated by the one or more sensors from the data gateway and display at least a portion of the data.

Abstract: The present invention discloses a measuring method for a semiconductor gas sensor based on alternating-current impedance. The method includes the steps: connecting the semiconductor gas sensor to a capacitor in parallel, connecting an alternating-current impedance measuring device to the semiconductor gas sensor and the capacitor, combining measuring parameters under measuring frequencies within a first preset range and parallel capacitance values within a second preset range, and measuring a gas with a known concentration according to each of nine features under each combination; traversing all parameter combinations and all the nine features to obtain a plurality of feature values corresponding to the same gas concentration under each feature; and selecting measuring frequencies within a third range, parallel capacitance values within a fourth range and a certain or several of the corresponding features as measuring parameters finally selected for measuring an unknown gas concentration.

Abstract: A biosensor component is provided that provides enhanced characteristics for use in biosensors, such as blood glucose sensors. The biosensor component comprises a substrate, a conductive layer deposited on the substrate, and a resistive material layer deposited on the conductive layer. The conductive layer includes nickel, chromium, and iron, such that a combined weight percent of the nickel and chromium in the conductive layer is in the range of 25 to less than 95 weight percent, the weight percent of nickel in the conductive layer is at least 4 weight percent, the weight percent of chromium in the conductive layer is at least 10 weight percent, the weight percent of iron in the conductive layer at least 2 weight percent, and such that the conductive layer comprises 0 to 20 weight percent molybdenum.

Abstract: A method of forming a glass electrochemical sensor is described. In some embodiments, the method may include forming a plurality of electrical through glass vias (TGVs) in an electrode substrate; filling each of the plurality of electrical TGVs with an electrode material; forming a plurality of contact TGVs in the electrode substrate; filling each of the plurality of contact TGVs with a conductive material; patterning the conductive material to connect the electrical TGVs with the contact TGVs; forming a cavity in a first glass layer; and bonding a first side of the first glass layer to the electrode substrate.

Abstract: The object of the invention is to increase the detection specificity of biosensors. The present invention provides a biosensor characterized in that it comprises an identifier substance that can bind to a detection target substance and an electrode that takes the charge of said identifier substance, wherein the biosensor detects the change in the charge density of said electrode generated by the binding of said detection target substance with said identifier substance, the surface of said electrode is coated with polycatecholamine, all or a part of said electrode surface coated with polycatecholamine further has a polymer layer formed thereon which has a molecular imprint having a structure complementary to the molecular structure of the detection target substance formed therein, said polymer layer comprises said identifier substance, and said polymer layer is an ultrathin film layer.

Abstract: A biosensor that can perform analysis based on a sample noninvasively collected from a human body is provided. The biosensor comprises an identification substance (38) that binds to a substance to be detected (40), and an electrode (16) charged with a charge of the identification substance (38), comprises an inhibitor (39) that inhibits a substance not to be detected (42) from attaching to at least one of the identification substance (38) and the electrode (16), and detects a change in a charge density of the electrode (16) caused by binding of the substance to be detected (40) to the identification substance (38).

Abstract: A method for diagnosing COVID-19 infection of a person. The method includes acquiring a sputum sample of the person, measuring a level of reactive oxygen species (ROS) in the sputum sample, and detecting a COVID-19 infection status of the person based on the measured level of ROS. Measuring the level of ROS in the sputum sample includes recording a cyclic voltammetry (CV) pattern from the sputum sample and measuring a current peak of the recorded CV pattern. Detecting the COVID-19 infection status of the person based on the measured level of ROS includes detecting the person is infected with COVID-19 if the measured current peak is in a first range of current peaks and detecting the person is not infected with COVID-19 if the measured current peak is in a second range of current peaks.

Abstract: Synchronized ion modification systems and techniques are described. An ion modifier can be used to modify a portion of ions that enter a drift chamber via a gate that controls entry of the ions to the drift chamber. A controller that is communicatively coupled to the ion modifier is configured to control the ion modifier to select a portion of the ion to be modified. In embodiments, the controller selects the portion based on a detector's previous response to other ions that are formed from a sample from which the ions were formed. The other ions, for example, correspond to ions that are associated with a peak in previous operation of a spectrometer.

Abstract: The method for non-destructive flaw detection of aluminium reduction cell anodes is claimed, including the building of a computed model of an anode or the use of a specified model with the known data on the geometry and specific resistance of the anode, the geometry and coordinates of internal defects, wherein several cyclic calculations are carried out; the results of calculations are represented in the form of a 3D-matrix of amplitudes and directions of vectors of calculated intensities or inductions of the electromagnetic field at the discretization points near the outer surface of the anode; at least a pair of electrically conductive contacts that supply the specified amount of electrical current through the anode are placed on the outer surfaces of the inspected anode; at least one sensor is placed near the outer surface of the inspected anode, and the amplitude and direction of the magnetic field intensity or induction vectors are measured and represented as a 3D-matrix of measured magnetic field intens

Abstract: A fluid mixture parameter determination (FMPD) system for analyzing a fluid mixture while moving includes a computing system and at least one material model that includes two or more model parameters for a plurality of material compositions stored in the memory. An ultrasonic sensor and a millimeter wave (MMW) sensor are each coupled to sense the fluid mixture and are coupled to the computing system. The ultrasonic sensor is for providing ultrasonic data to the computing system including a velocity of the fluid mixture or a volumetric flow, and a velocity of sound (VoS) through the fluid mixture. The MMW sensor is for providing MMW velocity data to the computing system. The computing system is for utilizing the material model together with the ultrasonic data and the MMW velocity data for identifying parameters including a plurality of components in the fluid mixture and a concentration for the plurality of components.

Abstract: Embodiments described herein utilize Non-Destructive Inspection (NDI) scan data obtained during a process performed on a surface of a structure to update a location of an NDI scanner on the surface. A subsurface feature within the structure is detected based on the NDI scan data, which are correlated with pre-defined position data for the subsurface feature. A measured location of the NDI scanner on the surface is corrected based on the pre-defined position data for the subsurface feature.

Abstract: The present disclosure provides a system and method for real-time visualization of a material during ultrasonic non-destructive testing. The system includes a graphical user interface (GUI) capable of showing a three-dimensional (3-D) image of a composite laminate constructed of a series of two-dimensional (2-D) cross sections. The GUI is capable of displaying the 3-D image as each additional 2-D cross section is scanned by an ultrasonic testing apparatus in real time or near real time, including probable defect regions that contain a flaw such as a hole, crack, wrinkle, or foreign object within the composite. Furthermore, in one embodiment, the system includes an artificial intelligence capable of highlighting defect areas within the 3-D image in real time or near real time and providing data regarding each defect area, such as the depth, size, and/or type of each defect.

Abstract: An ultrasonic inspection method in which a pulse signal is output to an ultrasonic sensor to generate and transmit ultrasonic waves, the ultrasonic waves reflected or scattered by an object are received and converted into a waveform signal by the ultrasonic sensor, and the waveform signal is digitized to acquire waveform data, includes: executing modulation processing for modulating a plurality of waveform data acquired in multiple inspections and under the same inspection conditions by a phase modulation method to generate composite waveform data; and executing demodulation processing for demodulating the composite waveform data to generate compressed waveform data.

Abstract: A system includes a sensor comprising a sensor bonding layer disposed on a surface of the sensor, wherein the sensor bonding layer is a metallic alloy. An inlay includes a planar outer surface, wherein the inlay may be disposed on a curved surface of a structure. A structure bonding layer may be disposed on the planar outer surface of the inlay, wherein the structure bonding layer is a metallic alloy. The sensor bonding layer is coupled to the structure bonding layer via a metallic joint, and the sensor is configured to sense data of the structure through the metallic joint, the structure bonding layer, and the sensor bonding layer. The inlay comprises at least one of a modulus of elasticity, a shape, a thickness, and a size configured to reduce strain transmitted to the sensor.

Abstract: An apparatus for in-situ calibration of a photoacoustic sensor includes a measurement device configured to measure an electric signal at an IR emitter of the photoacoustic sensor, wherein the IR emitter generates an electromagnetic spectrum based on the electric signal; and a calibration unit including processing circuitry, configured to compare the electric signal with a comparison value to generate a comparison result used as calibration information. When performing the in-situ calibration, the calibration unit is configured to adjust the electric signal based on the calibration information, or the calibration unit is configured to process an output signal of the photoacoustic sensor based on the calibration information to obtain an adjusted output signal of the photoacoustic sensor.

Abstract: Automation of the collection and reinjection of a sample into a large number of containers is made possible without increasing the size of a liquid handler itself.

Abstract: Yttria containing hybrid organic-inorganic sol-gels may be used in coatings for capillary microextraction, optionally hyphenated to online HPLC analysis. The sol-gel reaction mixture can use an yttrium trialkoxyalkoxide, such as yttrium trimethoxyethoxide, and a [bis(hydroxyalkyl)-amino-alkyl]-terminated polydialkyl/arylsiloxane, such as [bis(hydroxyethyl)-amine] (BHEA)-terminated polydimethylsiloxane, that can undergo hydrolysis and polycondensation, to form coating materials. Capillaries coated with such sol-gels can have improved extraction efficiency compared, e.g., to pure yttria-based coatings. The CME-HPLC can analyze water samples containing analytes of varied polarity, with excellent extraction of amides, phenols, alcohols, ketones, aldehydes, and polyaromatic hydrocarbons and detection limits ranging from 0.18 to 7.35 ng/mL (S/N=3). Such capillaries can exhibit solvent stability at pH 0 to 14, RSD % between 0.6 to 6.8% (n=3), at a preparative reproducibility RSD between 4.1 and 9.9%.

Abstract: A sample dispatcher for a fluid separation apparatus includes a sampling path including a sampling volume, a sampling unit, and a retaining unit. The sampling unit receives a fluidic sample, and the sampling volume temporarily stores an amount of the received sample. The retaining unit receives and retains from the sampling volume at least a portion of the stored sample, and has different retention characteristics for different components of the sample. A switching unit is coupled to the sampling path, a sampling fluid drive, a mobile phase drive, and a separating device. In a feed injection configuration of the switching unit, the mobile phase drive, the separating device, and the sampling path are coupled together in a coupling point for combining a flow from the sampling fluid drive containing the fluidic sample retained by the retaining unit with a flow of the mobile phase from the mobile phase drive.

Abstract: An on-line system that performs concentration and solvent exchange in order to improve a detection level of analytes by a liquid chromatograph (LC) is provided. The on-line system comprises: a first pump and a second pump for supplying a solvent; a liquid chromatograph (LC) including a separation column (SC) connected to the first pump; a trapping column (TC) for collecting the analytes separated from the separation column; a concentration column (CC) for concentrating the analytes collected in the trapping column (TC); a detector; and first to third switching valves that communicate fluid with at least one of the first or second pumps. An analysis method using the same is also provided.

Abstract: Methods and system for protein characterization using online chromatography and electrospray ionization mass spectrometry are provided.

Abstract: An analytical data analysis system (2) is a system that identifies composition substances contained in the sample to be analyzed and non-composition substances that are not the composition substance contained in the sample to be analyzed by comparing a standard chromatogram and an analysis target chromatogram.