Patents Issued in July 20, 2023
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Publication number: 20230225593Abstract: An image pickup apparatus of the present invention includes a first member including an illumination optical element and an observation optical element, an image pickup device, and a second member including a signal wire and an illumination member. The first member includes a first layer substrate including an illumination window and an observation window and a second layer substrate including a first illumination element and an observation lens, the second member includes a third layer substrate including a second illumination element and an opening in which the image pickup device is disposed and a fourth layer substrate including a third illumination element and a signal wire, the first member and the second member are stacked in order of the first layer substrate, the second layer substrate, the third layer substrate, and the fourth layer substrate and integrally bonded, and the first illumination element is a light emitting element.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Applicant: OLYMPUS CORPORATIONInventor: Takatoshi IGARASHI
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Publication number: 20230225594Abstract: A method for performing auto-focus in a camera is disclosed. The method includes: receiving, from a tracking system for tracking a position of a medical instrument, a signal; determining, based on the received signal, that the medical instrument is removed from a field of view of the camera; in response to determining that a continuous auto-focus mode for the camera is enabled: retrieving, from a database, a first focus distance value representing a focus distance that was most recently set with intent for the camera; and automatically updating a focus distance of the camera to the first focus distance value.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Applicant: SYNAPTIVE MEDICAL INC.Inventors: Luke William GANE, David Bruce GALLOP
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Publication number: 20230225595Abstract: A system comprising an adjustable mount arm, a bronchoscope coupled to the adjustable mount arm, an attachment coupled to the bronchoscope, and a steerable sheath coupled to the attachment and configured to be inserted through the bronchoscope. The system further includes a flexible probe configured to be inserted through the steerable sheath and the bronchoscope.Type: ApplicationFiled: January 18, 2022Publication date: July 20, 2023Inventors: Louis Mingione, Daniel Price, Kevin Royalty, Jeffrey Bissing, Samantha Weber, Nathan Clemans, Laura Wiley, Nathan Wallace, Eric Bielefeld
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Publication number: 20230225596Abstract: Presently disclosed is an endoscope comprising of an insertion tube sheath, which comprises one or more mechanical layers having a mechanical contraption, wherein one or more of the mechanical contraptions is made of shape memory material.Type: ApplicationFiled: December 9, 2020Publication date: July 20, 2023Inventor: Nitesh Ratnakar
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Publication number: 20230225597Abstract: A cholangioscope includes a catheter that is to be inserted into a body and has a curved shape, a camera shaft that can be inserted into the catheter and is formed in a curved shape, and a CMOS image sensor that is provided at a distal end portion of the camera shaft. The catheter further includes a forceps channel into which a medical instrument can be inserted, and a camera channel that is provided in an outer side portion of the catheter having the curved shape outer than the forceps channel and into which the camera shaft can be inserted. Curvature of the camera shaft is less than curvature of the catheter. The camera shaft is formed into a curved shape by using a shape memory alloy.Type: ApplicationFiled: October 13, 2022Publication date: July 20, 2023Inventor: Yuki KODAMA
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Publication number: 20230225598Abstract: A medical capsule, comprising an enclosure, the enclosure comprising an opening at one end along an axial direction; a PCB group and a functional unit which are arranged inside the enclosure; wherein the PCB group comprises a plurality of PCBs which are connected through flexible printed circuits and are spaced from each other, and the functional unit comprises a battery unit electrically connected to the PCB; and a pressure detection unit, comprising a pressure transmission film assembled at the opening, a pressure sensor positioned in the enclosure, and a pressure collecting and processing circuit board electrically connected to the pressure sensor, wherein the pressure collecting and processing circuit board is connected to one of the PCBs through a flexible printed circuit. The medical capsule is simple in structure, easy to equip and allows for expansion of functions as needed.Type: ApplicationFiled: May 28, 2021Publication date: July 20, 2023Applicants: Ankon Medical Technologies (Shanghai) Co., LTD., ANX IP HOLDING PTE. LTD.Inventors: Lei LIU, Xiaodong Duan
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Publication number: 20230225599Abstract: An imaging system includes a first optical system configured to receive an imaging beam from a surgical region. The imaging beam including a first wavelength band and a second wavelength band. The imaging beam is directed along a first optical axis. The first optical system includes a dichroic beam splitter, and the first optical system is configured to direct a first optical beam associated with the first wavelength band along a first direction and direct a second optical beam associated with the second wavelength band along a second direction. The imaging system also includes a first sensor located along the first direction and configured to capture a first image associated with the first optical beam. The image system further includes a first relay lens system located along the second direction downstream from the first optical system and configured to receive the second optical beam.Type: ApplicationFiled: January 20, 2022Publication date: July 20, 2023Inventors: Robert Trusty, Jeremiah Henley, Hannes Weise, Ralf Hambach
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Publication number: 20230225600Abstract: An imaging device includes a camera unit and a control unit. The camera unit includes an image sensor. The control unit includes a voltage measurement circuit and a voltage adjustment circuit. A first power source voltage is transferred from the control unit to the camera unit by a power source line and is input to the camera unit as a second power source voltage. A video signal or the second power source voltage is output to a video signal line. The voltage measurement circuit is configured to measure a voltage value of the second power source voltage. The voltage adjustment circuit is configured to adjust a value of the first power source voltage based on the value of the second power source voltage.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Applicant: OLYMPUS MEDICAL SYSTEMS CORP.Inventors: Takaharu TANI, Keisuke OGAWA, Yasunari HARADA
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Publication number: 20230225601Abstract: An endoscope includes a detachable wireless imaging device and an insertion tube having a distal end region. The attachment of the detachable wireless imaging device detachably attaches the detachable wireless imaging device to the distal end region of the insertion tube.Type: ApplicationFiled: December 17, 2022Publication date: July 20, 2023Applicant: PSIP LLCInventors: Lex BAYER, Rupesh DESAI, John HIGGINS
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Publication number: 20230225602Abstract: The lighted surgical access system is provided that includes a circumferential retractor and a plastic optical fiber (POF) attached thereto. The circumferential retractor retracts and protects a patient’s body opening while the POF illuminates the internal surgical site, body cavity and/or body opening.Type: ApplicationFiled: March 20, 2023Publication date: July 20, 2023Inventors: Alex Diehl, Luis Salazar, Andrew Nguyen, Jonathan Rothschild, Joel Velasco, Khodr Saleh, Alexis Penaloza, Ralph Sias, Tina Talwar, Cory Hague, Boun Pravong, Kennii Pravongviengkham, Suraj Sharma
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Publication number: 20230225603Abstract: A reconditioning apparatus for an endoscope including a controller configured to: supply an interior of the endoscope with a fluid at a predefined pressure; supply one or more channels of the endoscope and an exterior of the endoscope with a rinsing liquid to carry out a reconditioning process using the rinsing liquid; concurrently with the supplying of the rinsing liquid, determine a temperature and a pressure in the interior of the endoscope during the reconditioning process; and when the determined pressure decreases lower than a predetermined pressure: identify the endoscope as not defective, when the decrease in the determined pressure is preceded by a corresponding decrease in the determined temperature, and identify the endoscope as defective, when the decrease in the determined pressure is not preceded by a corresponding decrease in the determined temperature.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Applicant: OLYMPUS WINTER & IBE GMBHInventor: Jan Batista ANDRADE
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Publication number: 20230225604Abstract: An opening and closing unit includes a body that has a first hollow part penetrating through both ends thereof and an opening part communicating the first hollow part with an outside, and an opening and closing part that is inserted into the first hollow part to selectively open and close the opening part, has second hollow part formed therein, and has a through hole communicating with the second hollow part on one side thereof.Type: ApplicationFiled: May 23, 2022Publication date: July 20, 2023Inventor: Hyun Soo JI
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Publication number: 20230225605Abstract: A multifunctional laryngoscope is provided that includes a handle comprising a proximal end and a distal end and a display screen on the handle. The laryngoscope includes a laryngoscope camera at the distal end of the handle and an introducer comprising an orientation sensor at a distal end of the introducer. The laryngoscope includes a processor programmed to execute instructions for receiving from a steering input a steering command in a first reference frame, and mapping the steering command to a second reference frame oriented to the distal end of the introducer based on an orientation signal from the orientation sensor.Type: ApplicationFiled: March 17, 2023Publication date: July 20, 2023Applicant: Covidien AGInventors: Derek Scot Tata, Craig Allen Patton, Peter Douglas Colin Inglis
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Publication number: 20230225606Abstract: A cystoscope and system are disclosed in which a repository of the cystoscope is configured to receive a cartridge tool and provide access to a working channel of an elongated shaft of the cystoscope. The handle of the cystoscope has a first control for actuating a movable element of the repository. The movable element is configured to engage a cartridge tool received within the repository and thereby implement a functionality of the cartridge tool when the first control is actuated.Type: ApplicationFiled: January 18, 2023Publication date: July 20, 2023Applicant: Prodeon Medical, Inc.Inventors: Al Burdulis, Craig Purdy, Gary Daniel Zaretzka
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Publication number: 20230225607Abstract: A surgical system includes a detector, comprising an array of pixels configured to detect light reflected by a surgical instrument and generate a first signal comprising a first dataset representative of a visible image of the surgical instrument. The surgical system also includes a processor configured to receive the first signal, generate a modified image of the surgical instrument that includes a control panel. The control panel includes one or more control elements representative of one or more operating parameters of the surgical instrument. The processor is further configured to receive an input to the control panel from a user, the input being effective to change one of the operating parameters. The processor is also configured to generate a command signal based on the input to change the one of the operating parameters.Type: ApplicationFiled: January 6, 2023Publication date: July 20, 2023Inventors: Jeffrey S. Swayze, Joshua Young, Andrew Beckman
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Publication number: 20230225608Abstract: Devices and methods can be used for performing transoral surgery. For example, this document provides oral retractor devices and articulating surgical tools that are well-suited for transoral surgery uses. The devices and methods provided herein may be used to treat conditions such as, but not limited to, mouth cancer, throat cancer, tongue cancer, larynx cancer, tonsil cancer, obstructive sleep disorders, and pharyngeal diverticulum, to provide some examples.Type: ApplicationFiled: January 4, 2023Publication date: July 20, 2023Applicant: Mayo Foundation for Medical Education and ResearchInventors: Kathryn M. Van Abel, Eric J. Moore
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Publication number: 20230225609Abstract: Embodiments of the invention are directed towards systems, methods and computer program products for providing improved eye tests. Such tests improve upon current eye tests, such as visual field tests, by incorporating virtual reality, software mediated guidance to the patient or practitioner such that more accurate results of the eye tests are obtained. Furthermore, through the use of one or more trained machine learning or predictive analytic systems, multiple signals obtained from sensors of a testing apparatus are evaluated to ensure that the eye test results are less error-prone and provide a more consistent evaluation of a user's vision status. As it will be appreciated, such error reduction and user guidance systems represent technological improvements in eye tests and utilize non-routine and non-conventional approaches to the improvement and reliability of eye tests.Type: ApplicationFiled: January 29, 2021Publication date: July 20, 2023Inventors: Alberto O. GONZALEZ GARCIA, Freddy Salomon MORGENSTERN
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Publication number: 20230225610Abstract: A portable ocular screening device for tracking macular degeneration having a portable body including a graduated focusing mechanism including an inner chamber. The apparatus also includes a monocular eyepiece disposed on the graduated focusing mechanism and a display screen and a processor disposed within the inner chamber. Additionally, a method of monitoring macular degeneration includes providing a monocular screening device having a display screen disposed within a body of the screening device. The method further includes displaying an image and also providing a prompt in response to the display of the image. Subsequently, the method includes receiving a response via an input device, the response indicative of a user's perception of the image and evaluating the response to determine if the response indicates a user accurately perceived the first image.Type: ApplicationFiled: June 4, 2021Publication date: July 20, 2023Inventors: Jacob Lutz, Vichal Palandira Muthanna, Andrew Yu, Mario Russo, Rachel Sun, Yannis Paulus
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Publication number: 20230225611Abstract: The invention relates to a method of processing data representative of a person’s binocular motricity, the method comprising the following steps: stimulating the binocular motricity of a person by means of a binocular motricity stimulation device (21) configured to specifically stimulate saccades, vergences or a combination of both or of a reading test (22); physical stimuli in 3D real space seen with both eyes naturally (without artifices); acquiring the movement of the right eye (RE) and the left eye (LE) of a person (P) during said stimulation and, if applicable, a stimulation signal from the binocular motor stimulation device; the method comprising the following steps implemented in a processing unit (3); determination from the movement of the left eye (LE) and the right eye (RE), of an effective trajectory (Tr1) of the eyes in response to each stimulation, an effective trajectory corresponding to a saccade and/or a vergence movement of the eyes.Type: ApplicationFiled: May 7, 2021Publication date: July 20, 2023Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS CITEInventor: Zoi KAPOULA
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Publication number: 20230225612Abstract: In some embodiments, techniques for using machine learning to enable visible light pupilometry are provided. In some embodiments, a smartphone may be used to create a visible light video recording of a pupillary light reflex (PLR). A machine learning model may be used to detect a size of a pupil in the video recording over time, and the size over time may be presented to a clinician. In some embodiments, a system that includes a smartphone and a box that holds the smartphone in a predetermined relationship to a subject's face is provided. In some embodiments, a sequential convolutional neural network architecture is used. In some embodiments, a fully convolutional neural network architecture is used.Type: ApplicationFiled: March 20, 2023Publication date: July 20, 2023Applicant: University of WashingtonInventors: Lynn B. McGrath, Anthony Law, Randall Bly, Shwetak N. Patel, Alex T. Mariakakis, Jacob Baudin
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Publication number: 20230225613Abstract: Method and system for a non-invasive assessment of a relation between an intracranial pressure and an intraocular pressure. The method comprising the steps of recording a plurality of images of a retina part of an eye of a person, identifying at least one vein, determining a first plurality of characteristic vein diameters for the identified vein at a first vein location, determining whether the at least one vein has experienced a vein collapse during the first time period, and determining a relation between intraocular pressure and intracranial pressure during the first time period.Type: ApplicationFiled: June 17, 2020Publication date: July 20, 2023Inventor: Jakob Find Munk Madsen
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Publication number: 20230225614Abstract: A veterinary vital signs monitoring system, including: (A) two stretchable bands, each having an electrically conductive component; (B) a housing including two fasteners with electrically conductive contacts, each fastener adapted to receive, and lock therein a portion of one of the bands, the conductive contacts adapted to make an electrical connection with electrically conductive components of the bands; and (C) a module housed in the housing and in electrical communication with the conductive contacts, the monitoring module adapted to receive signals relating to vital signs of the animal on which the bands are mounted, via the conductive components thereof.Type: ApplicationFiled: January 5, 2023Publication date: July 20, 2023Inventor: Avi YOSEF
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Publication number: 20230225615Abstract: Various embodiments of systems, devices and methods for improving the accuracy of an analyte sensor and for detecting sensor fault conditions are disclosed. According to some embodiments, these systems, devices, and methods can utilize a first data collected by a glucose sensor and a second data collected by a secondary sensing element. In some embodiments, the secondary sensing element can be one of a lactate sensing element, a ketone sensing element, or a heart rate monitor, among others.Type: ApplicationFiled: June 7, 2021Publication date: July 20, 2023Inventors: Erwin S. Budiman, Yi Wang, Benjamin Jay Feldman, Hyun Cho, Kuan-Chou Chen, Lam N. Tran, Stephen Oja, Tianmei Ouyang
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Publication number: 20230225616Abstract: A catheter system for optical coherence tomography includes an elongate catheter body, an optical fiber in the elongate catheter body, and an anamorphic lens assembly coupled with a distal end of the optical fiber. The optical fiber and the lens assembly are together configured to provide a common path for optical radiation reflected from a target and from a reference interface between the distal end of the optical fiber and the lens assembly.Type: ApplicationFiled: March 14, 2023Publication date: July 20, 2023Inventors: Himanshu N. PATEL, Manish KANKARIA, Kin F. CHAN
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Publication number: 20230225617Abstract: A breast cancer diagnosis system includes a probe that sequentially outputs light of a plurality of wavelengths of a near-infrared area to a target object, receives reflected light, and sequentially processes the reflected light; a central control device that receives optical data of the reflected light sensed by the probe, calculates a concentration of chromophore of the target object for each chromophore, and generates an image of the chromophores indicating a distribution of the concentration value of each chromophore; and a display that outputs the image, in which in the probe, one or more channel signal processing units including one or more light irradiation modules and light collection modules may be disposed, and each of the channel signal processing units sequentially operates so that each of the channel signal processing units may generate the optical data of the reflected light.Type: ApplicationFiled: March 27, 2023Publication date: July 20, 2023Applicant: OLIVE HEALTHCARE INC.Inventors: Sung Ho HAN, Hyon Soo PARK, Hee Sun HONG, Suk Jin CHOI, Soon Hyun BAN
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Publication number: 20230225618Abstract: A photoacoustic remote sensing system for imaging a subsurface structure in a sample, comprising exactly one laser source configured to generate a pulsed or intensity-modulated excitation beam configured to generate ultrasonic pressure signals in the sample at an excitation location, and an interrogation beam incident on the sample at the excitation location, a portion of the interrogation beam returning from the sample that is indicative of the generated ultrasonic pressure signals, an optical system configured to focus the excitation beam and the interrogation beam below a surface of the sample, a detector configured to detect the returning portion of the interrogation beam, and a processor configured to calculate an image of the sample based on a detected intensity modulation of the returning portion of the interrogation beam from below the surface of the sample.Type: ApplicationFiled: December 21, 2022Publication date: July 20, 2023Applicant: ILLUMISONICS INC.Inventors: Parsin HAJI REZA, Kevan BELL
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Publication number: 20230225619Abstract: An electronic device includes a housing sidewall defining an opening and a display component, such as a display cover, disposed in the opening to form a gap between the housing sidewall and the display component. In at least one example, the cavity is defined by the sidewall and the display cover with the cavity in fluid communication with an external environment through the gap. In at least one example, an epoxy component at least partially defines the cavity and can be in direct contact with the housing sidewall.Type: ApplicationFiled: September 22, 2022Publication date: July 20, 2023Inventors: Sherry Tang, Erik G. de Jong, Tyler S. Atura Bushnell, Daniel J. Hiemstra
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Publication number: 20230225620Abstract: Various techniques are disclosed to provide for improved detection of elevated human body temperatures. In one example, a method includes receiving a thermal image. The method also includes processing the thermal image to detect a person's face and a characteristic associated with the person. The method also includes selecting a circadian rhythm model associated with the detected characteristic. The method also includes determining an expected body temperature using the circadian rhythm model. The method also includes extracting a temperature associated with the person's face from the thermal image. The method also includes comparing the extracted temperature with the expected body temperature to detect an elevated body temperature condition. Additional methods and systems are also provided.Type: ApplicationFiled: March 15, 2023Publication date: July 20, 2023Inventors: Jonas Sandsten, Nicklas Bahram Ramberg
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Publication number: 20230225621Abstract: A system for evaluating a cardiac pumping function includes an oximeter which is attached to a patient for the purpose of recording a pulse oximeter waveform. A computer is connected to the oximeter to receive metric information from the waveform. With this information, the computer determines the value and location of a second derivative acceleration, d2A/dt2 in the waveform, which indicates the rate of rise/fall of the waveform. A comparator in the computer then compares this with the value and location of maximum second derivative acceleration, d2A/dt2, in earlier waveforms. With this comparison, the computer identifies a trend which can be clinically used to evaluate the efficacy of a cardiac pumping function.Type: ApplicationFiled: January 20, 2022Publication date: July 20, 2023Inventor: Guy P. Curtis
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Publication number: 20230225622Abstract: The invention relates to a method for determining the microvascular resistance reserve, MRR, in the myocardium perfused by a normal or a stenotic coronary artery of a human patient, which method comprises the step of during rest condition of the patient: measuring the blood flow, Qrest, through the coronary artery; and further comprising the step of during rest condition or during maximum hyperemia of the patient: measuring the blood pressure, Pa, at a position proximal in the coronary artery or proximally of any stenosis, if present; and further comprising the steps of during maximum hyperemia of the patient: measuring the blood flow, Qmax, through the coronary artery; and measuring the blood pressure, Pd, at a position distal in the coronary artery or distally of any stenosis, if present, and wherein the microvascular resistance reserve, MRR, is determined by the additional step of calculating the microvascular resistance reserve as M ? R ? R = Q max Q rest ? P a P d , h ? y ? p ? e ? rType: ApplicationFiled: May 31, 2021Publication date: July 20, 2023Applicant: Coroventis Research ABInventors: Nico H.J. Pijls, Bernard De Bruyne
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Publication number: 20230225623Abstract: An exemplary embodiment of the present disclosure provides systems and methods for non-invasively measuring blood pressure, the system and methods comprise a wearable device having a first surface, a first sensor positioned on the first surface of the wearable device, the first sensor configured to receive a first signal, wherein the first signal is indicative of a first blood-volume change in a first vessel of a subject, a second sensor positioned within the wearable device, the second sensor configured to receive a second signal, wherein the second signal is indicative of a cardiac mechanical motion of the subject, and a processor positioned within the wearable device, the processor configured to generate an output based at least on the first signal and the second signal, the output representing a blood pressure measurement of the subject.Type: ApplicationFiled: March 19, 2021Publication date: July 20, 2023Inventors: Andrew M. Carek, James A. Heller, Mozziyar Etemadi, Avidor B. Kazen, Omer T. Inan, Venu G. Ganti
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Publication number: 20230225624Abstract: A method for monitoring blood pressure (BP) of a user using a cuffless monitoring system comprising a pulsatility waveform measuring device configured to measure a pulsatility waveform signal of the user, the method comprising an initialization routine (10) including performing an adequacy routine (20) for adjusting the measurement parameters of the pulsatility waveform measuring device (103); and performing a reliability test for determining a reliability of the measurement. The method provides incremental feedback of the adequacy of the acquired signals, the reliability of pulsatility waveforms, and the repeatability of the absolute BP values.Type: ApplicationFiled: May 15, 2020Publication date: July 20, 2023Inventors: Josep Maria SOLA i CAROS, Elisa OLIVERO, Olivier GROSSENBACHER, Bastien DE MARCO, Natalija IGNJATOVIC, Blagoje IGNJATOVIC, Matthieu FAVRE-BULLE, Sibylle FALLET, Anna VYBORNOVA
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Publication number: 20230225625Abstract: The present specification describes methods and systems for on-inflate non-invasive blood pressure (NIBP) measurement suitable for cuffs of various sizes. In embodiments, an adapter hose connecting the cuff to the NIBP device is dynamically identified. Embodiments provide a restriction in at least one of the valves in the NIBP device to enable a controlled release of air from the device during the cuff inflation process.Type: ApplicationFiled: January 20, 2022Publication date: July 20, 2023Inventors: Jeffrey Jay Gilham, Nishant Gopalakrishnan
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Publication number: 20230225626Abstract: In a noncontact vital sign sensing device of the present invention, a gain detector is provided to detect a gain between an oscillation signal and a received signal. Gain detection can cancel out the amplitude noise of an oscillator such that frequency information of vital sign(s) of a subject can be extracted from the gain without null-point issue, and vital sign(s) of the subject located at any position within sensing range can be detected.Type: ApplicationFiled: May 12, 2022Publication date: July 20, 2023Inventors: Kang-Chun Peng, Tzyy-Sheng Horng, Fu-Kang Wang, Meng-Che Sung
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Publication number: 20230225627Abstract: A device (1) for monitoring a response of a subject body (2, 21, 211) comprises an emitter (3) for emitting an input signal (5, 51, . . . ) and a receiver (4) for receiving an output signal (6, 61, . . . ). A first response (R1) of the subject body (2, 21, 211) is evaluated from the comparison between the signals. A further emitter (31, 311, . . . ) evaluates a second response (R2), wherein one of the responses is selected for a further monitoring of the response, and/or at least one further receiver (41, 411, . . . ) evaluates a third response (R3), wherein either the first response (R1) or the third response (R3) is selected for a further monitoring of the response, and/or wherein the input signal (5, 51, . . . ) is an electromagnetic field and the device (1) further comprises a signal modulator (9) which alters the input signal (5, 51, . . . ).Type: ApplicationFiled: March 27, 2023Publication date: July 20, 2023Applicant: VIGILITECH AGInventors: Harald OSSWALD, Marc ZÜND, Daniel ZÜND
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Publication number: 20230225628Abstract: A method for performing magnetic resonance imaging on a subject comprises: injecting a contrast agent into a region of interest of the subject; applying a pulse sequence to the region of interest; collecting auxiliary data for the region of interest, the auxiliary data being related to one or more time-varying parameters of the subject within the region of interest; determining a temporal factor ? from the auxiliary data; collecting imaging data for the region of interest, the imaging data being related to one or more spatially-varying parameters of the subject within the region of interest; determining a spatial factor Ur from the imaging data; modeling a multi-dimensional image sequence as I=Ur?; and deriving at least a first metric and a second metric from the multi-dimensional image sequence I, the first metric and the second metric being associated with distinct perfusion-based imaging techniques.Type: ApplicationFiled: June 16, 2021Publication date: July 20, 2023Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Zhaoyang Fan, Anthony Christodoulou, Debiao Li, Zhehao Hu
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Publication number: 20230225629Abstract: An example apparatus includes a shell portion configured to be worn over a head of a subject. The shell portion defines a plurality of apertures. The apparatus also includes a plurality of spherical fiducial structures disposed on the shell portion. Each of the fiducial structures includes a first material doped with a second material. The second material is a contrast agent for magnetic resource imaging (MRI). The apparatus also includes a mounting structure disposed on the shell portion and configured to secure the shell portion to the head of the subject.Type: ApplicationFiled: June 21, 2021Publication date: July 20, 2023Inventors: Kendall H. Lee, Stephen J. Goerss, Aaron E. Rusheen, Benjamin T. Gifford, Andrew J. Fagan
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Publication number: 20230225630Abstract: A system and method for denoising experimental data originating from multiple acquisitions by a magnetic resonance imaging device, by analysis of selected principal components, to obtain a better compromise between the efficiency of the denoising and retention of the relevant information in the experimental data under consideration during their reconstruction to produce denoised experimental data. A selection criterion is based on the informative indicators quantifying the spatial information contained in images of scores associated with said principal components. The invention also provides for the capability to apply an adaptive filtering excluding the persistent spatial noise associated with each component selected.Type: ApplicationFiled: March 16, 2023Publication date: July 20, 2023Applicant: OLEA MEDICALInventors: Stefano CASAGRANDA, Christos PAPAGEORGAKIS, Mauro ZUCCHELLI
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Publication number: 20230225631Abstract: A mouthpiece is disclosed through which a user inhales and exhales when providing an exhaled breath sample. The mouthpiece includes a mouth-engaging element about which a user places their mouth when using the mouthpiece and also a housing having a housing wall. The housing wall defines a first aperture through the housing wall, the first aperture being linked by a conduit defining a first fluid flow path to the mouth-engaging element. Interposed therebetween is a first directional valve, allowing air into the mouthpiece from atmosphere. A second conduit is provided, defining a second fluid flow path from the mouth-engaging element, and directing exhaled air out of a second aperture of the mouthpiece. The second conduit houses a second directional valve housed within the second fluid flow path.Type: ApplicationFiled: July 28, 2021Publication date: July 20, 2023Inventors: Stig Lytke BREJL, Roger YTTERVIK
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Publication number: 20230225632Abstract: A setting device comprising at least one processor, wherein the processor is configured to: acquire imaging part information indicating an imaging part of a subject whose radiographic image is captured by radiation emitted from a radiation emitting device; acquire body thickness information indicating a body thickness of the subject in a direction in which the radiation is transmitted; acquire condition information indicating whether a tube voltage value and a mAs value are each set to variable or fixed; and derive a set value of the tube voltage and a set value of the mAs value of the radiation emitting device for emitting the radiation such that a dose of the radiation transmitted through the imaging part is the same as a dose at a reference body thickness, on the basis of the imaging part information, the body thickness information, and the condition information.Type: ApplicationFiled: March 23, 2023Publication date: July 20, 2023Inventor: Tetsuya TSUJI
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Publication number: 20230225633Abstract: The invention provides a body-worn system that continuously measures pulse oximetry and blood pressure, along with motion, posture, and activity level, from an ambulatory patient. The system features an oximetry probe that comfortably clips to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. Analog versions of these signals pass through a low-profile cable to a wrist-worn transceiver that encloses a processing unit. Also within the wrist-worn transceiver is an accelerometer, a wireless system that sends information through a network to a remote receiver, e.g. a computer located in a central nursing station.Type: ApplicationFiled: March 20, 2023Publication date: July 20, 2023Applicant: SOTERA WIRELESS, INC.Inventors: Jim Moon, Devin McCombie, Matt Banet, Marshal Dhillon
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Publication number: 20230225634Abstract: A wearable device for monitoring physical activity of a user, the wearable device being reversibly attachable to a chest strap and an arm strap. The wearable device comprises an ECG sensor arranged to collect ECG measurements of the user only when the wearable device is attached to the user's chest by the chest strap, and a PPG sensor arranged to collect PPG measurements of the user when the wearable device is attached to the user's arm or wrist by the arm strap. The wearable device also comprises control circuitry arranged to switch the wearable device between an ECG only mode and a PPG only mode. In the ECG only mode, the control circuitry is configured to control the ECG sensor to collect ECG measurements but prevent the PPG sensor from initiating PPG measurements. In the PPG only mode, the control circuitry is configured to control the PPG sensor to initiate PPG measurements but prevent the ECG sensor from collecting ECG measurements.Type: ApplicationFiled: June 23, 2021Publication date: July 20, 2023Inventors: David Edward WRIGHT, Michael Glenn LEVEQUE
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METHODS AND SYSTEMS FOR FACILITATING INTERACTIVE TRAINING OF BODY-EYE COORDINATION AND REACTION TIME
Publication number: 20230225635Abstract: A computer implemented method for facilitating training of body-eye coordination using a computing device having access to a camera is disclosed. The method includes receiving a training video of a player from the camera; superimposing a visual cue onto the training video; extracting a body posture flow of the player from the training video by performing a computer vision algorithm on one or more frames of the training video; determining whether the player has responded to the visual cue by analyzing the body posture flow of the player; and generating a feedback to the player in response to determining that the player has responded to the visual cue. Multi-player embodiments of the present invention are also disclosed.Type: ApplicationFiled: March 24, 2023Publication date: July 20, 2023Inventors: Qi Zhang, Wing Hung Chan, Arron Mollet, Keng Fai Lee -
Publication number: 20230225636Abstract: Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior.Type: ApplicationFiled: March 8, 2023Publication date: July 20, 2023Applicant: President and Fellows of Harvard CollegeInventors: Sandeep Robert Datta, Alexander B. Wiltschko, Matthew J. Johnson, Geetika Bajaj
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Publication number: 20230225637Abstract: In some embodiments, the electronic device includes a speaker, a microphone, a memory, a digital signal processor (DSP), a driver, and a processor. The processor is configured to: obtain a first sound signal by combining a first signal, a second signal, and a first anti-phase signal; extract, from a second sound signal related to the first sound signal, a first DPOAE signal; obtain a third sound signal by combining a fourth signal, a fifth signal, and a second anti-phase signal; extract, from a fourth sound signal related to the third sound signal, a second DPOAE signal; obtain a user hearing profile based on the first and second DPOAE signals; and perform, based on the user hearing profile, at least one of a sound volume change and an equalization (EQ) change of a sound to be output.Type: ApplicationFiled: March 20, 2023Publication date: July 20, 2023Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Taehan LEE, Jungkeun PARK, Seonghun JEONG, Jonghee HAN, Kiyean KIM, Taeseon KIM
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Publication number: 20230225638Abstract: An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry readings at a number of different tissue locations of a patient and average two or more of the oximetry readings by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry readings if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry readings which are instantaneous measurement for patient tissue.Type: ApplicationFiled: October 18, 2022Publication date: July 20, 2023Inventors: Alex Michael Margiott, William Welch, Sushant Potdar, Scott E. Coleridge
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Publication number: 20230225640Abstract: An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry readings at a number of different tissue locations of a patient and average two or more of the oximetry readings by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry readings if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry readings which are instantaneous measurement for patient tissue.Type: ApplicationFiled: October 18, 2022Publication date: July 20, 2023Inventors: Alex Michael Margiott, William Welch, Sushant Potdar, Scott E. Coleridge
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Publication number: 20230225641Abstract: An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry readings at a number of different tissue locations of a patient and average two or more of the oximetry readings by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry readings if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry readings which are instantaneous measurement for patient tissue.Type: ApplicationFiled: October 18, 2022Publication date: July 20, 2023Inventors: Alex Michael Margiott, William Welch, Sushant Potdar, Scott E. Coleridge
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Publication number: 20230225642Abstract: An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry readings at a number of different tissue locations of a patient and average two or more of the oximetry readings by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry readings if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry readings which are instantaneous measurement for patient tissue.Type: ApplicationFiled: October 18, 2022Publication date: July 20, 2023Inventors: Alex Michael Margiott, William Welch, Sushant Potdar, Scott E. Coleridge
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Publication number: 20230225643Abstract: The invention refers to a photonic integrated circuit (PIC), the photonic integrated circuit comprising: at least one laser, the laser having a laser output, a measuring portion including a measuring port and configured to measure an intensity and/or wavelength of light input at the measuring port, and an output portion configured to output light from the photonic integrated circuit to the portion of the tissue, wherein optionally the laser includes a ring resonator laser, a laser generating light having a fixed wavelength, a laser being constructed using hybrid integration, and/or a tunable laser.Type: ApplicationFiled: November 17, 2022Publication date: July 20, 2023Inventors: Adam SCOFIELD, Babak BAHARI, Abu THOMAS, Andrea TRITA, Aaron John ZILKIE