Abstract: The systems, devices, and methods herein make optoacoustic measurements and correct or normalize them for variations in optical energy level of the different light pulses used. An optical source directs optical pulses to tissue, an optical energy meter measures the optical energy of the different optical pulses, an acoustic detector measures an acoustic response generated by the tissue in response to the optical pulses, and a processor calculates a concentration of an analyte based on the measured acoustic response and as corrected or normalized for the different energy levels among the optical pulses.

Abstract: An exemplary method is disclosed that can be used in the diagnosis of hypertrophic cardiomyopathy (HCM) using a biophysical-sensor system configured to non-invasively and concurrently acquire electrocardiographic signals, seismographic signals, photoplethysmographic, and/or phonocardiographic signals, collectively referred to herein as biophysical signals, from at least the thoracic region of a subject. The acquired biophysical signals may be assessed for one or more conditions or indicators of hypertrophic cardiomyopathy and concurrently with other cardiac diseases, conditions, or indicators of either.

Abstract: A vital signal detection device includes: an antenna unit provided with a planar antenna of a MIMO radar on a front surface; and a display unit including a display panel on the front surface. The antenna unit is combined with the display unit or the display unit is combined with the antenna unit in a rotatable manner so that, from a state where the planar antenna and the display panel face in a direction ahead of the front surface, the planar antenna is turned to be directed to a direction of a back surface of the display unit opposite from the display panel. The portable non-contact vital signal detection device detects a vital signal on a side ahead of the front surface and a vital signal on a side in the direction of the back surface opposite from the front surface.

Abstract: Systems and methods for measuring vitals in accordance with embodiments of the invention are illustrated. One embodiment includes a method for measuring vital signs. The method includes steps for identifying regions of interest (ROIs) from video data of an individual, generating temporal waveforms from the ROIs, analyzing the generated temporal waveforms to extract vital sign measurements, and generating outputs based on the analyzed temporal waveforms.

Abstract: According to an aspect, there is provided a computer-implemented method for determining a heart rate of a subject, the method comprising: receiving data representing a signal generated by a pressure sensor configured to be placed on a suprasternal notch of a subject, the data representing a first component of the signal comprising respiratory information associated with the subject and/or a second component of the signal comprising cardiac information associated with the subject; determining, by applying a first algorithm to the data, a respiration parameter of the subject; applying at least one filter to the data to obtain first filtered data, the at least one filter comprising a first filter to attenuate the first component of the signal in the data based on the determined respiration parameter; and determining a heart rate of the subject by applying a second algorithm to the first filtered data.

Abstract: The present disclosure discloses a PPG sensor, an electronic device and a wearable device. The PPG sensor includes a first light-emitting assembly configured to emit a first optical signal; a second light-emitting assembly configured to emit a second optical signal; and a plurality of photoelectric sensors configured to receive the first optical signal and the second optical signal. A distance between the first light-emitting assembly and at least one of the plurality of photoelectric sensors is greater than a minimum one of the distances between the second light-emitting assembly and each of the plurality of photoelectric sensors.

Abstract: A system includes a processor circuit configured to receive a first set of data. The first set of data includes two pressure measurements and a flow measurement from the vasculature of a patient obtained while the sympathetic nervous system of the patient is not under stimulation. The processor circuit calculates a blood flow resistance value based on the first set of data. The processor circuit then receives a second set of data. The second set of data also includes two pressure measurements and a flow measurement from the vasculature of the patient obtained while the sympathetic nervous system of the patient is stimulated. The processor circuit calculates another blood resistance value based on the second set of data. The processor circuit then compares the two blood flow resistance values to determine whether a denervation procedure would be effective to mitigate the nerve system's response to stimulation. The processor circuit outputs to a screen display metrics obtained from the measurement procedure.

Abstract: Spinal device/implants are provided, comprising a spinal device/implant and a sensor.

Abstract: An apparatus includes a mounting portion and a sensor portion. The mounting portion is configured to fit over a nose of a preselected patient. The mounting portion includes a base and a pair of rigid nose pads fixedly coupled to the base. Each nose pad of the pair of nose pads includes a respective nose-gripping surface. The nose-gripping surfaces of the nose pads are configured to engage the nose of the preselected patient at respective predetermined locations along the nose. Each nose-gripping surface is sized and shaped to complement a corresponding unique structural feature of the nose of the preselected patient at the predetermined location. A sensor portion is fixedly attached to the mounting portion. The sensor portion includes a first sensor configured to generate a first signal corresponding to a position of the first sensor in three-dimensional space.

Abstract: Disclosed is an image processing device for estimating a position of an endoscope in a model of the human airways using a first machine learning data architecture trained to determine a set of anatomic reference positions, said image processing device comprising a processing unit operationally connectable to an image capturing device of the endoscope, wherein the processing unit is configured to obtain a stream of recorded images; continuously analyse the recorded images of the stream of recorded images using the first machine learning data architecture to determine if an anatomic reference position of a subset of anatomic reference positions, from the set of anatomic reference positions, has been reached; and where it is determined that the anatomic reference position has been reached, update the endoscope position based on the anatomic reference position, and an endoscope system comprising an endoscope and an image processing device, a display unit comprising an image processing device, and a computer progr

Abstract: An apparatus and methods enhances the energy levels of a person, in particular the relating to guiding a person's breathing to enhance energy and health. The device is a breath guide device having an airway, breathflow guiding equipment, a control unit capable of communicating with a memory unit. The control unit is arranged to control the breathflow guiding equipment in dependence on data held in the memory unit. A mouthpiece suitable for placement at a user's mouth may be included. The breathflow guiding equipment includes an electronically operated valve for regulating the flow of breath through the airway.

Abstract: A diagnostic tool and methods of using the tool are provided to quantify an amount of nasal collapse in a patient. The diagnostic tool includes a mask with an endoscope port and an opening to allow air flow, an endoscope with a camera adapted to take an image of the nasal valve, and an air flow sensor adapted to measure an inhalation rate of the patient. The diagnostic tool can quantify a size difference between the nasal valve during inhalation and zero flow by calculating a percentage difference in an area or one or more dimensions of the nasal valve during inhalation and zero flow.

Abstract: A wearable respiration monitoring system having a transmitter coil that is adapted to generate and transmit multi-frequency AC magnetic fields, two receiver coils adapted to detect variable strengths in two of the AC magnetic fields and generate AC magnetic field strength signals representing anatomical displacements of a monitored subject, and at least one accelerometer that is configured to detect and monitor anatomical positions and movement of the subject, and generate and transmit accelerometer signals representing same. The wearable monitoring system further includes an electronics module that is adapted to receive the AC magnetic field strength signals and accelerometer signals, and determine at least one respiratory disorder as a function of the AC magnetic field strength signals and at least one anatomical position of the subject as a function of the accelerometer signals.

Abstract: A person support apparatus, such as a bed, stretcher, cot, recliner, or the like, includes an exit detection system having a plurality of force sensors that support the weight of an occupant positioned on a support surface and obstruction detection system having one or more obstruction sensors. The force sensors are part of an exit detection system that issues an alarm when the occupant exits, or is about to exit, the person support apparatus. The bed exit system can react to detection of an obstacle. The distribution of weight applied to the force sensors is used to determine if the occupant is about to exit the person support apparatus. Compensation is made to the exit detection system for changes in the weight distribution that are not caused by movement of the occupant. Such changes may be due to not only movement of the person support apparatus or components thereof, but obstacles encountered by the person support apparatus or components thereof.

Abstract: A motion monitoring method (500) is provided, which includes: obtaining a movement signal of a user during motion, wherein the movement signal includes at least an electromyographic signal or an attitude signal (510); and monitoring a movement of the user during motion based at least on feature information corresponding to the electromyographic signal or the feature information corresponding to the attitude signal (520).

Abstract: Exemplary embodiments of wearable stretch sensors and applications of using the same are disclosed. In embodiments, the sensors and the applications disclosed herein can be used to capture spinal motion and posture information.

Abstract: A method for human action recognition in a human-machine interactive assembly scene is disclosed in this application, joint coordinate streams of skeleton joints are obtained under a human action from motion sensing devices; a starting position and an ending position of the action are positioned according to data change based on a threshold value to obtain information of joints; resampling of angle change is made on the information of joints to obtain coordinates of joints; the coordinates of joints are normalized, to obtain a sequence of skeletons forming an action; obtaining a vector direction of the upper limb, and the scene is classified to be a left-hand scene or a right-hand scene; training is made for human action recognition in the left-hand scene and the right-hand scene respectively; human action outputs of the left-hand scene and the right-hand scene are fused to realize action recognition in a human-machine interaction scene.

Abstract: A solution for non-invasive determination of supraphysiological body joint kinematics. The solution obtains external images related to a test procedure of the body joint and performs image analysis on the obtained images to define a pattern of a plurality of spatial points in a region of interest. Each individual spatial point is defined by a unique pattern of neighboring surrounding pixels in each image, and the pattern is part of a high-contrast speckle pattern applied to the body joint. The solution identifies displacements of the spatial points in subsequently obtained images by tracing a location of the unique pattern of neighboring pixels in each image in relation to a base image of the body joint, calculates deformation measures from the displacements of the plurality of spatial points, and obtains deformation measures of a reference body joint. The solution compares the deformation measures and determines supraphysiological body joint kinematics from the comparison.

Abstract: An instrument configured to test the middle-ear function of a test subject, such as in tympanometry and impedance audiometry is provided.

Abstract: Systems include an invasive sensor and a non-invasive sensor for detection of analytes. The invasive sensor detects one or more non-invasively detected analytes, and the non-invasive sensor detects one or more invasively detected analytes. The one or more non-invasively detected analytes and the one or more invasively detected analytes can include at least one analyte in common, or do not include any analytes in common.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: Provided is a blood measurement device capable of accurately estimating the amount of a component contained in blood by passing light beams for calculating the amount of the component contained in blood along the same optical axis. A blood measurement device 10 of the present invention includes a light emitting part 11 having a first light emitting part 111 and a second light emitting part 112, a light receiving part 19, an actuator 16, and a computation and control part 17 that estimates a glucose level and controls operation of the actuator 16.

Abstract: This disclosure relates to a method of manufacturing an in vivo analyte sensing device, which is adapted for detecting at least one analyte in a body fluid or tissue and an in vivo analyte sensing device obtainable by said manufacturing method. Further, this disclosure relates to a method of manufacturing a sensor base plate and a sensor base plate obtainable by said manufacturing method. The sensor base plate may be used for the manufacture of an in vivo analyte sensing device.

Abstract: Methods, apparatuses, and systems are provided for determining whether to administer a medication dose as a single dose or whether to fractionate the single dose to be administered as at least two discrete doses. Embodiments include determining a first analyte level and a first rate of change of the analyte level; determining an initial medication dose based on one or more anticipated subsequent medication doses, the first analyte level relative to an analyte level threshold, and the first rate of change of the analyte level relative to a rate of change threshold; administering the initial medication dose; determining a second analyte level and a second rate of change of the analyte level based on subsequent analyte data; and determining a subsequent medication dose based on the second analyte level relative to the analyte level threshold and the second rate of change relative to the rate of change threshold.

Abstract: Detection devices, systems, and methods include those for detecting analytes (e.g., volatile organic compounds (VOCs) and/or other chemical substances) from a target area of a subject's anatomy (e.g., a subject's skin, a wound on a subject, etc.). In some cases, a detector may have a detecting component that includes an analyte sensitive material applied to a substrate. The detector may be used with a pump. The detector may include a hydrophobic, gas permeable material configured to limit liquid reaching the analyte sensitive material, while allowing analytes in gaseous fluid to reach the analyte sensitive material.

Abstract: A system for measurement is provided. The system includes a scanning interface module for placement on a skin for non-invasive scanning. The scanning interface module includes a cavity to be pressed on the skin to make a vertical portion in the cavity, and a nonlinear optical system for scanning the vertical portion via an input side and an output side of the cavity that are laterally facing each other.

Abstract: A noninvasive physiological sensor can include a first body portion and a second body portion coupled to each other and configured to at least partially enclose a user's finger. The sensor can further include a first probe coupled to one or more emitters and a second probe coupled to a detector. The first probe can direct light emitted from the one or more emitters toward tissue of the user's finger and the second probe can direct light attenuated through the tissue to the detector. The first and second probes can be coupled to the first and second body portions such that when the first and second body portions are rotated with respect to one another, ends of the first and second probes can be moved in a direction towards one another to compress the tissue of the user's finger.

Abstract: An oximetry device sealed in a sheath directs a user to allow the oximetry device to make oximetry readings at a number of different tissue locations of a patient and average two or more of the oximetry readings by directing the lifts and placements of the oximetry device and sheath to and from the different tissue locations and detecting the lift and placements. The averages are generated and displayed on a display of the device for the oximetry readings if the lifts are made while use directions for the lifts are displayed on a display of the oximetry device. The averages are not generated if the lifts are not made while the user directions for the lifts are not displayed. The averages are simultaneously displayed with the oximetry readings which are instantaneous measurement for patient tissue.

Abstract: A light sensing device includes a first light source configured to emit light within a first wavelength range, a second light source configured to emit light within a second wavelength range, detector circuitry, a first photodetector in the detector circuitry configured to detect the light within the first wavelength range, and a second photodetector in the detector circuitry configured to detect the light within the second wavelength range. The first photodetector and the second photodetector are in parallel in the detector circuitry such that the detector circuitry sums electrical signals outputted by the first photodetector and the second photodetector.

Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.

Abstract: A system for blood draw including a catheter adapter having a catheter and a side inlet defining a fluid pathway into and out of the catheter. The system also includes a near-patient access port member having a main branch with a distal end couplable to the side inlet and a proximal end having a needle access connector coupled thereto. The system further includes a blood draw device removably couplable to the near-patient access port member, wherein the blood draw device includes a cannula configured to penetrate the needle access connector, a flow tube configured to be advanced and retracted through the cannula, and a tube advancement tab coupled to the flow tube and configured to linearly advance and retract the flow tube through the cannula such that the flow tube may be selectively directed through the blood draw device, the near-patient access port member, and the catheter adapter.

Abstract: Systems and methods to determine if an individual is impaired. The system includes a display and a stimulus on the display. The system include a controller that is programmed to move the stimulus about the display and one or more sensors that track eye movements and pupil size of a user due to movement of the stimulus or light conditions. The system includes a processor programmed to analyze the eye movements and pupil data size. The method includes using a testing apparatus and collecting data from the testing apparatus. The method includes storing the collected data. The method includes processing the data with an automated impairment decision engine to determine whether a test subject is impaired. The method may include using machine learning models or statistical analysis to determine whether a test subject is impaired. The automated impairment decision engine may be trained using machine learning and/or statistical analysis.

Abstract: There is described a method and system for measuring a level of anxiety. Measured data comprising EEG data collected from a parietal (P) EEG electrode is received. A group 8 indicator based on a power, P-power (dt), associated with a delta-theta frequency band, dt, within a delta-theta frequency range is extracted. Based on said group 8 indicator, a level of anxiety, LoA, is determined which is a value indicative of the level of anxiety of the subject.

Abstract: An apparatus for providing information about a user's brain resources is provided. The apparatus includes at least sensor interface circuitry and processing circuitry coupled to the sensor interface circuitry. In a calibration mode, the sensor interface circuitry is configured to receive first sensor data from an electroencephalography sensor. The first sensor data are indicative of an electroencephalogram of the user. Further, the sensor interface circuitry is configured to receive second sensor data from a physiological sensor in the calibration mode. The second sensor data are indicative of a physiological property of the user. In the calibration mode, the processing circuitry is configured to train a brain-physiological model for the user based on the first sensor data and the second sensor data.

Abstract: A method includes receiving multimodal data collected using at least one wearable device during an assessment window. The method also includes extracting biomarker features from the multimodal data, based on changes in the extracted biomarker features. The method also includes detecting that a stress event occurred during the assessment window. The method also includes accessing a plurality of templates of patterns in biomarker features, wherein a first subset of the templates is associated with unhealthy response to stress and a second subset of the templates is associated with healthy response to stress. The method also includes determining whether the stress event corresponds to a healthy response or an unhealthy response based on similarities between a pattern in the extracted biomarker features and the plurality of templates. The method also includes responsive to the stress event corresponding to an unhealthy response, providing a stress management recommendation.

Abstract: Urine collection systems and associated methods and devices are disclosed herein. A representative system can include a urine collection device, a flow control assembly configured to direct a urine flow from the patient to the urine collection device, and a urine measurement device including a first sensor and a second sensor. The first sensor is configured to generate first sensor data based on a weight of the container, and the second sensor is configured to generate second sensor data based on the urine flow from the patient to the container. The system can further include non-transitory computer readable media having instructions that, when executed by one or more processors, cause the system to perform operations comprising determining a first patient urine output based on the first sensor data; and determining a second patient urine output based on the second sensor data.

Abstract: Disclosed are a skin-attachable adhesive patch mimicking a leg structure of a diving beetle and having excellent skin-attachment ability even in a dry or wet condition, and a method for manufacturing the same. The skin-attachable adhesive patch includes a substrate; a plurality of negative pressure chambers formed on a surface of the substrate, wherein each of the plurality of negative pressure chambers has a truncated hollow sphere structure; a micro-wrinkle layer formed on at least a portion of a remaining area of the substrate except for an area thereof where the negative pressure chambers are formed; and a patterned carbon particle layer formed on the micro-wrinkle layer.

Abstract: A biosignal sensing electrode that includes: a conductive film containing particles of a layered material including one or plural layers, the one or plural layers includes a layer body represented by: MmXn, wherein M is at least one metal of Group 3, 4, 5, 6, or 7, X is a carbon atom, a nitrogen atom, or a combination thereof, n is 1 to 4, m is more than n and 5 or less, and a modifier or terminal T exists on a surface of the layer body, wherein T is at least one selected from a hydroxyl group, a fluorine atom, a chlorine atom, an oxygen atom, or a hydrogen atom; and a porous membrane that contains a hydrophilic polymer, the porous membrane having a first surface in contact with at least part of the conductive film and a second surface defining a contact surface with a subject.

Abstract: In a method for extracting physiological data of an object under examination from ECG signals as part of MR imaging, raw ECG data comprising ECG signals may be captured from at least three electrodes located at different positions on an object under examination. The raw ECG data may be processed, which may include performing a first filtering using a first filter configured to extract an electrocardiogram, performing a second filtering using a second filter configured to identify a heartbeat, performing a third filtering using a third filter configured to extract and/or represent a respiratory movement, and/or performing a fourth filtering using a fourth filter configured to identify breathing. The processed raw ECG data including physiological data of the object under examination may be provided as an output.

Abstract: A medical device is configured to sense an electrical signal and determine that signal to noise criteria are met based on electrical signal segments stored in response to sensed electrophysiological events. The medical device is configured to determine an increased gain signal segment from one of the stored electrical signal segments in response to determining that the signal to noise criteria are met. The medical device determines a noise metric from the increased gain signal segment. The stored electrical signal segment associated with the increased gain signal segment may be classified as a noise segment in response to the noise metric meeting noise detection criteria.

Abstract: An estimation apparatus is configured to be capable of accessing a model storage unit that stores a model built by machine learning, using, as training data, information on a predetermined sound and information relating to a signal source of a signal indicating a brain activity of a first subject presented with the predetermined sound, the model outputting information on a sound estimated to be recognized by the subject. The estimation apparatus acquires a brain wave of a second subject presented with the predetermined sound. The estimation apparatus estimates, based on a mode of the brain wave acquired, a signal source of the brain wave, from among a plurality of regions in a brain of the second subject. The estimation apparatus inputs the information relating to the signal source estimated to the model and acquires information on a sound estimated to be recognized by the second subject.

Abstract: The method can include a muscle deforming a fiber path and activating a joint of the mammal, circulating electricity along the fiber, along the length of the fiber path, generating a movement signal including monitoring a change of impedance of the fiber stemming from the deformation of the muscle path during said deformation of the fiber path, determining a coefficient of correlation value of successive portions of the movement signal associated to corresponding, successive, time windows, including ascertaining a degree of similitude between the corresponding portion and a corresponding movement template, and generating an indication of muscle fatigue based on said coefficient of correlation values.

Abstract: A method of assessing or monitoring the normal skin sympathetic nerve activity in a living subject, the subject having a skin, comprises assessing or measuring electrodermal activity, wherein the electrodermal activity is skin conductance, galvanic skin response, electrodermal response, psychogalvanic reflex, skin conductance response, sympathetic skin response or skin conductance level. Skin conductance may be assessed by calculating skin conductance fluctuation peaks per time unit, and when the skin conductance fluctuations peaks are above a certain predefined value, the normal skin sympathetic nerve activity is defined in an analyzing window with a length of about 15 to 60 seconds, the normal skin sympathetic nerve activity is assessed as being obtained or successful. Alternatively, the skin conductance may be assessed by calculating rise time of the mean skin conductance level, the area under the skin conductance fluctuations or the size of the amplitude of the skin conductance fluctuation.

Abstract: A system includes a processor circuit in communication with an anatomical measurement device. The anatomical measurement device receives a metric associated with a sympathetic response of a patient. The sympathetic nervous system of the patient is then stimulated. The anatomical measurement device then receives another metric associated with a sympathetic response of the patient while the sympathetic nervous system is stimulated. The processor circuit then provides an output based on the comparison.

Abstract: A method and device for predicting Alzheimer's disease based on voice characteristics are provided. The device for predicting Alzheimer's disease according to an embodiment includes: a voice input unit configured to generate a voice sample by recording a voice of a subject; a data input unit configured to receive demographic information of the subject; a voice characteristic extraction unit configured to extract voice characteristics from the generated voice sample; and a prediction model that is pre-trained to predict presence or absence of Alzheimer's disease in the subject, based on the voice characteristics and the demographic information.

Abstract: Disclosed is a method of identifying dementia by at least one processor of a device. The method includes performing a first task that causes a first object to be displayed on a first region of a screen displayed on a user terminal; and when a preset condition is satisfied, performing a second task that causes at least one object, which induces the user's gaze, to be displayed instead of the first object on the screen of the user terminal.

Abstract: Disclosed is a method of identifying dementia by at least one processor of a device according to some embodiments of the present disclosure. The method may include obtaining a plurality of result data of a user obtained by performing a plurality of tests through a user terminal, calculating a score value by inputting the plurality of result data to a dementia identification model, and determining whether the user has dementia based on whether the score value is greater than a first threshold value.

Abstract: A vaginal insert device and method of use for improving and preventing symptoms associated with pelvic organ prolapse and urinary and/or fecal incontinence, administer medication or topical treatment, and/or collect a sample when the device is inserted, or any combination thereof. The vaginal insert device may be cone-shaped, may have a removal portion, may have external ridges, may have internal ribs, may have an open or closed top, or combinations thereof. The device may include cavities, diagnostic devices, and/or microchips.

Abstract: In some embodiments, a wound monitoring and/or therapy apparatus includes a wound dressing configured to be positioned in contact with a wound, the wound dressing comprising one or more sensors configured to obtain measurement data of at least one of the wound or periwound. The apparatus can also include a controller configured to maintain a device clock indicative of a non-real time clock, receive measurement data obtained by the one or more sensors, and transmit measurement data to a remote computing device according to a security protocol, the security protocol comprising including the device clock associated with the measurement data in the transmission.

Abstract: Disclosed are a method and apparatus for sleep monitoring, an electronic device and a computer readable medium, relating to the field of health monitoring technology, the method comprises: a screen state of a target terminal is obtained; physiological parameters of a user are obtained, the physiological parameters including at least one of body motion parameters and heart rate parameters; a sleep state of the user is determined based on the screen state and the physiological parameters. Since the screen state can reflect the user's operation of the user terminal, and the operation can further reflect the sleep state of the user, and the physiological parameters can also reflect the sleep state of the user, the combination of the screen state and the physiological parameters can make the determination of sleep state more accurate.