Abstract: A slip-resistant patch for a tongue bulb employs a planar body configured to conform to a surface of the tongue bulb. The planar body has a first major surface and an opposing second major surface. The first major surface is textured and the second major surface is adhesive. The textured material is configured to be positioned on a surface of an oral cavity and maintain position on the surface of the oral cavity throughout lingual movement within the oral cavity. The adhesive material is of a pressure sensitive material and being configured to adhere to the surface of the tongue bulb. At least one tether extends from the planar body along the perimeter portion. The at least one tether is configured to be wrapped around a stem of the tongue bulb for securing the slip-resistant patch to the tongue bulb.

Abstract: Methods and devices for treating and occluding a female patient's fallopian tubes to provide permanent or extended birth control or sterilization.

Abstract: An ophthalmic device can be positioned on a surface of an eye and can modulate an amount of light that can be transmitted therethrough in response to environmental factors and/or release of a therapeutic agent into the eye. The ophthalmic device can include an electronically-mediated medium that can modulate an amount of light transmitted in response to a first electrical signal generated by a signal generator. The ophthalmic device also can include at least one drug reservoir that can release a therapeutic agent to the eye in response to a second electrical signal generated by the signal generator. The signal generator can be encapsulated within the ophthalmic device and in communication with a controller that defines parameters of the electrical signals generated by the signal generator.

Abstract: A syringe with multiple chambers of isolated constituents for advancing to a mixing chamber in furtherance of delivery to tissue within an eye of a patient. The syringe also includes a mixing mechanism that is in communication with the mixing chamber. Additionally, the isolated chambers may be one of sequential or side by side/parallel depending on the types of constituents to be combined and other surgical preferences.

Abstract: An ocular implant adapted to be disposed within Schlemm's canal of a human eye with a body extending along a curved longitudinal central axis in a curvature plane, a first strut on one side of the implant and a second strut on an opposite side of the implant, the circumferential extent of the first strut with respect to the plane of curvature being greater than the circumferential extent of the second strut with respect to the plane of curvature. The invention also includes methods of using the implant.

Abstract: An ophthalmic infusion support and associated methods are shown. Example infusion support devices include a base unit, a fixation device coupled to the bottom surface of the base unit, and an infusion tube holding device configured to hold a loop of an infusion tube an angle projecting upward from the patient.

Abstract: A method of preparing an occlusive wound dressing involves preparing a slurry of an occlusive composition with a hydrophobic compound and a bacteriostatic agent, applying the occlusive composition on a fabric to produce a coated fabric, disposing the coated fabric in packaging, adding water onto at least one of the coated fabric and the packaging, sealing the packaging containing the coated fabric, and irradiating the sealed package to sterilize and produce the occlusive wound dressing. The occlusive wound dressing has from about 60 wt % to about 75 wt % hydrophobic compound, from about 2 wt % to about 5 wt % bacteriostatic agent, from about 2 wt % to about 5 wt % water, and from about 5 wt % to about 36 wt % fabric.

Abstract: A method for applying absorbing inserts in a process for the production of pull-up diapers, includes: feeding a composite elastic web, including at least one elastic element, along a path and according to an advancing direction, conferring said composite elastic web with an application tension such that the composite elastic web has an elongation lower than a nominal maximum elongation thereof and the elastic element has a second percentage elastic elongation lower than first percentage elastic elongation corresponding to the nominal maximum elongation; applying absorbing inserts on an intermediate portion of the composite elastic web while the composite elastic web advances with said application tension, such that, once the tension is completely released, the absorbing inserts remain substantially flat and do not form substantial folds or wrinkles.

Abstract: A rigid mobility device for supporting a person having an injury as a patient in an upright position relative to the ground includes a first caregiver support platform, a second caregiver support platform, and a patient support platform. The first caregiver support platform and the second caregiver support platform can each rest on the shoulders of first and second caregivers. The patient support platform can support the arms of the patient.

Abstract: Disclosed herein is a backrest interlocking type frame for a foldable wheelchair.

Abstract: A body support sling (100) for supporting a patient from a patient hoist (10). The sling (100) comprises a leg support portion (60) adapted to support the thighs of a patient and a torso support portion (70) adapted to support the torso of a patient. According to an aspect of the invention, the sling (100) comprises a connecting portion (40). The connecting portion (40) comprising a front pair of suspension straps (41, 42) and a rear pair of suspension straps (43, 44) each being adapted to be connected to the patient hoist (10), the front pair of suspension straps (41, 42) being adapted to extend in front of the patient and the rear pair of suspension straps (43, 44) being adapted to extend behind the patient when the sling (100) is worn by the patient. The rear pair of suspension straps (43, 44) are attached to the torso support portion (70) and the front pair of suspension straps (41, 42) are attached to the leg support portion (60).

Abstract: A drive-thru medical facility having a vehicle pathway and a clinic building. The vehicle pathway has an entrance; at least one diagnosis bay positioned downstream of the entrance; an intermediate section positioned downstream of the at least one diagnosis bay; a first exit positioned downstream of the intermediate section; and at least one parking space, which can optionally extend from the intermediate section. Each diagnosis bay of the at least one diagnosis bay is configured to receive a respective vehicle. The clinic building is positioned to be accessible by a passenger of a vehicle parked within a parking space of the at least one parking space.

Abstract: Massage cushion has been used in Shiatsu and Thai massage for many years, its weak point is that there is no breathing hole like massage table. Massage clients are not comfortable and easier to get neck sprains. This invention is to take the advantage of semi-solid foam board to be the filler of massage cushion, so we can open breathing hole on one side of massage cushion, and open a ditch like horizontal air channel connected to the breathing hole. Accordingly the fabric case of the massage cushion is opened a breathing hole at the same location, and assembly two or three stainless steel airholes closer the outlet of air channel. So that the revised massage cushion become one side breathing hole cushion, one side for massage, and the other side can be used for gym exercise.

Abstract: A shoulder hold-down is provided for use in securing at least a shoulder of a patient in position relative to a surgical frame. The shoulder hold-down includes a locking mechanism that is adjustable to afford positioning of a shoulder engaging portion for contacting the patient.

Abstract: An electronic device and a wearable device providing exercise posture evaluation information, and operation methods thereof are disclosed. The electronic device includes: an input module configured to receive a user input that selects an exercise program to be performed by a user wearing the wearable device; a communication module configured to receive, from the wearable device, sensor data including movement information of the user during an exercise performed by the user according to the selected exercise program; a processor configured to determine an exercise posture measurement value of the user based on the sensor data, and generate a first visual guide object including a first indicator indicating an exercise posture reference for the selected exercise program and at least one second indicator indicating the exercise posture measurement value; and a display module configured to output a graphical user interface (GUI) on which the first visual guide object is displayed.

Abstract: A rollator includes a collapsible frame supported on a plurality of wheels, a pair of handlebars, and a braking mechanism.

Abstract: A massage device includes a base sheet with a sheet shape and an air bag supported by the base sheet. When one surface of the base sheet is a front surface and a surface opposite to the front surface is a back surface, the air bag includes a bag that is located on a side of the front surface of the base sheet, and that is inflated with air intake and deflated with air exhaust, and a sandwiching portion that is located on a side of the back surface of the base sheet and sandwiches the base sheet between the sandwiching portion and the bag in a thickness direction.

Abstract: A percussive massaging device has a base which includes a tool receiver and a piston for providing percussive action to a massage tool. The massage tool includes an attachment for selectively attaching to the tool receiver using one of a key and keyway system and a magnetic system. The attachment post further includes a press-fit seal or a magnetic mechanism for further securing the attachment post to the tool receiver. The massage tool further includes a tool head which may be non-rotating or is capable of rotating in one or more directions during use while simultaneously providing a percussive massage to a user.

Abstract: A container forming apparatus includes a plurality of forming members that have outer forming surfaces, which are shaped to form pockets in a sheet of material. A plurality of actuators are in mechanical connection with the forming members. The actuators are able to extend and retract the forming members. A controller is in electrical communication with the plurality of actuators. The controller is able to simultaneously extend any one or any combination of the forming members to create a plurality of pockets in a determined pattern in the sheet of material to produce a customized blister pack.

Abstract: A pill pouch is disclosed. The pill pouch can include a receptacle to contain a pill. The receptacle can have an opening to receive the pill therein. The receptacle can be defined at least in part by a flexible side to facilitate breaking or crushing of the pill inside the receptacle. The pill pouch can also include an access feature associated with the receptacle to facilitate removal of the pill from the receptacle after the pill has been broken and/or crushed.

Abstract: Provided herein are patient-controlled oral liquid-medicine dispenser and deactivation systems. The system includes a dosing container having a defined volumetric capacity and a spillway adapted and configured to allow fluid in excess of the defined volumetric capacity to flow out of the dosing container; a sealed and tamperproof waste receptacle fluidly coupled to the dosing container, the waste receptacle adapted and configured to capture and prevent diversion of liquid medicine dispensed in excess of the defined volumetric capacity of the dosing container; and a suction apparatus extending between a lower region of the dosing container and outside of the dosing container. Also provided herein are methods of administering a medication using the system.

Abstract: A pharmacy tray for medications and medical items for patient treatment kit is placed onto a shelf that carries a grid of optical presence sensors. The location and identification of each item in the tray is recorded on a digital inventory for that tray. At the patient treatment site each item taken is recorded and the remaining inventory is updated without scanning the items. Each pharmacy tray bears a unique identifier that can be read at the patient treatment site to obtain the kit inventory for that tray.

Abstract: A medication management device that enables healthcare professionals and their families to immediately ascertain whether a patient has taken the medicine he/she should have taken at the correct time. The present invention with holding unit 12 capable of holding the packaged medicine 32, detection unit 15 capable of detecting changes in the state of holding unit 12, and judgment unit 16 to determine that medicine 32 has been removed when detection unit 15 detects a change in the state of holding unit 12, enables healthcare professionals and their families to immediately ascertain whether a patient has taken the medication he/she should have taken at the correct time.

Abstract: There is provided a multi-layered sheet mask comprising at least (a) a porous first layer having a first side and a second side, wherein the first side is opposite to the second side, and comprises a plurality of three-dimensional patterns extending therefrom; (b) a second layer attached to the second side of the porous first layer, the second layer comprising at least one pouch for receiving or containing at least one first active ingredient; a porous support structure; an air pouch that is sandwiched between the second side of the porous first layer and the porous support structure; and a plurality of microchannels that extend from the pouch and beyond the first side of the porous first layer when the air pouch is deflated; and (c) a third layer attached to the second layer for receiving or containing at least one second active ingredient.

Abstract: The present invention relates to a solid composition comprising: a) one or more anionic surfactants of sulfate type, present in a total amount ranging from 10% to 35% by weight, relative to the total weight of the composition; b) one or more anionic surfactants of sulfonate type; c) one or more cationic polymers; and d) one or more (poly)glycerol esters.

Abstract: Various aspects according to the present disclosure relate to a water-in-oil emulsion composition. The composition includes a continuous oil phase. The continuous oil phase includes an oleochemical component, a surface-treated pigment component, and a surfactant component. The composition further includes a dispersed water phase including water and at least one solubilized material.

Abstract: The present invention relates to the field of medicinal tissue mineralisation, in particular, i.e. tooth remineralisation and bone regeneration with self-assembling peptides. Use of self-assembling peptides, such as P11-4, also designated Oligopeptide-104, in these processes leads to generation of hydroxyapatite, which is also present in natural enamel, dentin and bone. The inventors have discovered that both tooth remineralisation and bone regeneration can be significantly accelerated by adding amorphous calcium phosphate or calcium and phosphate ions that, when mixed in solution, can lead to immediate precipitation of calcium phosphate, preferably, amorphous, i.e., non-crystalline calcium phosphate. The presence of self-assembling peptide however changes the structure of the precipitated calcium phosphate, and advantageously induces crystallisation and a synergistic accelerated formation of crystalline calcium phosphate, in particular, hydroxyapatite (HA).

Abstract: Described herein are aspherical hollow silica particles, processes for making aspherical hollow silica particles, and uses of aspherical hollow silica particles in sun care compositions. To form the aspherical hollow silica particles, deposition of a silica shell on a calcium carbonate template using a sol-gel chemistry is employed. Subsequent dissolution of the calcium carbonate template forms voids (e.g., a hollow interior) in the aspherical hollow silica particles.

Abstract: Hair care products and methods are provided. A hair care product includes: a single-phase hair care composition emulsifiable with water before use, and a measuring vessel for measuring the hair care composition and/or the water for an application, wherein the measuring vessel is provided with a scale or marking or is correspondingly limited in size, which enables measuring the hair care composition and/or the water for the application, or instructions that enable a person to measure the desired quantities.

Abstract: A structured surfactant blend comprising a first and second anionic surfactant and amphoteric surfactant can form a liquid crystal structure. A sulfate-free aqueous personal cleansing composition comprising the same comprises high level of oil without sacrificing the quality and quantity of foam or lather.

Abstract: The present invention relates to a composition comprising: (b) at least one first polyglyceryl fatty acid ester having an HLB value of 12.0 or more, preferably 12.5 or more, and more preferably 13.0 or more; (c) at least one second polyglyceryl fatty acid ester having an HLB value of 10.0 or less, preferably 9.5 or less, and more preferably 9.0 or less; (d) at least one skin care active ingredient. The composition according to the present invention can enhance or improve the penetration of the ingredient (d) into the skin as compared to a case in which the combination of the ingredients (b) and (c) is not used.

Abstract: The present invention relates to a cosmetic or dermatological composition in the form of an emulsion, comprising: (a) a fat-soluble photoprotective system consisting of one or more fat-soluble UV filter(s) selected from: (i) hexyl 2-[4-(diethylamino)-2 hydroxybenzoyl]benzoate, (ii) 2,4-bis[4-(2-ethythexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, (iii) butyl methoxydibenzoylmethane, (iv) ethythexyl triazone, and (v) diethylhexyl butamido triazone: (b) a solubilising system of the fat-soluble photoprotective system (a), comprising C12-C15 alkyl benzoate in a quantity greater than or equal to 80% by weight, preferably greater than or equal to 90% by weight, relative to the total weight of the solubilising system; and (c) one or more particulate organic UV filters, which are in particular hydro-dispersed and are selected from: (vi) 5,6,5?,6?-tetraphenyl-3,3?-(1,4-phenylene)-bis[1,2,4]triazine, (vii) methylene bis-benzotriazolyl tetramethylbutylphenol, (viii) tris-biphenyl triazine; characterised i

Abstract: They have the general Formula X-(Xaa)nLE(Xaa)m-Z wherein Xaa is selected from L, K, E and D, either n=2 and m=0, or n=1 and m=1, at the N-terminal end X being selected from H, —CO—R1, —SO2-R1 or a biotinoyl group, at the C-terminal end Z being selected from OH, OR1, NH2, NHR1 or NR1R2, and R1 and R2 being selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy, saccharide and aryloxy, said group having from 1 to 24 carbon atoms. Preferred peptide sequences are X-LKLE-Z and X-ELED-Z. These tetrapeptides stimulate the synthesis of molecules constituting the ECM, in particular collagen 1 and 4, hyaluronic acid and fibronectin, and can be used for a cosmetic treatment, in particular anti-aging, anti-wrinkle and fine lines, to improve the skin mechanical properties, to increase skin density and volume, hydration, and/or to fight against stretch marks, and skin sagging.

Abstract: The invention is directed to a stable composition wash composition. The wash composition comprises a mixture of naturally derived and biodegradable sulfated polysaccharides. The wash composition has a viscosity of 40,000 cps or less, and surprisingly, is free of syneresis, discoloration and malodor, even after being stored at elevated temperatures.

Abstract: The present invention relates to a skin-care composition comprising beta-glucan and a natural oil, as well as either one or both of hydrogen peroxide and lactic acid. The skin-care composition is mainly based on natural ingredients. The composition has biocidal/anti-microbial activity and is very skin-friendly and non-irritative. The skin-care composition contains beta-glucan, which has an emulsifying effect, as well as a smoothening and moisturizing effects on the skin. A skin-care composition of the present invention does not negatively affect the barrier function of the skin.

Abstract: A color-changing oral care composition, in particular a dentifrice composition, contains: (i) an encapsulated dye particle comprising a dye and a coating layer encapsulating the dye, where the coating layer comprising hydroxy propyl methyl cellulose (HPMC) and polyvinyl alcohol (PVA), and (ii) 0.2% to 1.2% by weight of the composition, of flavor ingredients, where the flavor ingredients have a clog P value of 2 to 6, and where the flavor ingredients have Hansen Solubility Parameter (HSP) Distance (Ra) with hydroxy propyl methyl cellulose (HPMC) greater than 7.5, and Hansen Solubility Parameter (HSP) Distance (Ra) with polyvinyl alcohol (PVA) greater than 3.5.

Abstract: Injectable composition in hydrogel form, comprising water, hyaluronic acid, and nicotinamide for inhibiting the action of the hyaluronidase in the injected condition of the composition.

Abstract: Topical film forming compositions that are able to efficiently deliver active ingredients to keratinic surfaces in a timed release manner comprise a combination of acrylates copolymer and acrylates/VA copolymer, and a combination of propane-1,3 diol and glycerin. The sizes of the pores that develop in the dried film may be controlled or fine tuned.

Abstract: A marker composition suitable for skin may use a dye with good color development, which is capable of preventing color separation and also preventing absorption of the dye into the skin or the like. Such a marker composition may contain at least 1 to 5 mass % of an acid dye, an aminoalkyl (meth)acrylate copolymer, a water-soluble organic solvent, and water. The pH may be lower than 7.0. The aminoalkyl (meth)acrylate copolymer may be a copolymer polymerized from monomers selected from Group A (ethyl (meth)acrylate, methyl (meth)acrylate, n-propyl (meth)acrylate, and the like) and from Group B (2-(dimethylamino)ethyl (meth)acrylate, 2-(diethylamino)ethyl (meth)acrylate, and 3-(dimethylamino)propyl (meth)acrylate) respectively, and a ratio of the monomer of the group B may be 2 to 20 mass % in the copolymer.

Abstract: The present disclosure provides a resin composition, an adhesive-dropping material, an adhesive-pressing material, and a preparation method and application thereof. The resin composition comprises the following components: an ester-based prepolymer; a reactive diluent; and a photoinitiator; wherein the addition amount of the ester-based prepolymer is 60 to 80 parts by weight, the addition amount of the reactive diluent is 15 to 30 parts by weight, and the addition amount of the photoinitiator is 1 to 5 parts by weight, based on the part by weight. The artificial nail prepared by using the resin composition, the adhesive-dropping material, and the adhesive-pressing material according to the present disclosure has high mimicry. When in use, the artificial nail which is not completely hardened may be attached to the surface of the real nail and then hardened by UV light, so that the artificial nail is more conformable.

Abstract: An agent for dyeing keratinous material (e.g. human hair) is disclosed. The agent comprises at least one amino-functionalized silicone polymer; at least one color-imparting compound; and at least one addition product of C1-C6 alkylene oxide(s) to the esters of C12-C30 fatty acids and C1-C12 aromatic alcohols. A method for dyeing keratinous material is also disclosed, and comprises applying the agent to keratinous material, exposing the agent to the keratinous material, and rinsing the keratinous material to remove the agent.

Abstract: This invention provides ink particles comprising a) a core comprising a coloring agent and a polymer, and b) an outermost layer comprising a surfactant or a dispersant, wherein the core further comprises an outer surface and the outermost layer at least partially covers the outer surface of the core.

Abstract: To provided provide an oil-based cosmetic in which a pattern such as uneven or streak-like flow marks is reduced or inhibited, and which has excellent appearance gloss. An oil-based cosmetic of the present disclosure contains a first photoluminescent pigment having an average particle size of 80 ?m or less; and a polymeric oil-phase thickener, wherein the mass ratio of the first photoluminescent pigment and a second photoluminescent pigment having an average particle size of more than 80 ?m is 55:45 to 100:0, when the oil-based cosmetic contains a coloring material, the mass ratio of the first photoluminescent pigment with respect to the coloring material is 2.0 or higher, the content of thickening particles is less than 4.0% by mass, and the oil-based cosmetic has a viscosity of 50 mPa·s or higher under a temperature in at least a portion of a range of 80 to 150° C.

Abstract: Disclosed are compositions and methods for the treatment of pain and/or inflammation. In certain embodiments, the disclosed compositions and methods have anti-inflammatory activity. In some embodiments, the disclosed compositions and methods have analgesic activity. The present disclosure provides that two non-steroidal anti-inflammatory agents, as for example, 2-(4-isobutylphenyl)propanoic acid (ibuprofen), acetylsalicylic acid (aspirin), a muscle relaxant, and cannabidiol (CBD) can be used in combination in a topical formulation as an effective analgesic and/or anti-inflammatory agent.

Abstract: An immunotherapy delivery system includes a hydrogel with an immunomodulatory cargo including cells encapsulated in the hydrogel, a cell adhesion motif in the hydrogel configured to reversibly adhere to and release the cells, and an immunomodulatory cargo encapsulated in the hydrogel. The hydrogel includes a polymer non-covalently crossed-linked with a plurality of nanoparticles.

Abstract: The present invention relates to methods for treating a subject with risk factors for progression to iRORA, iRORA, nGA, cRORA, GA, AMD, intermediate AMD, dry AMD, and/or wet AMD, in a subject in need thereof comprising administration of an effective amount of an anti-C 5 agent or a pharmaceutically acceptable salt thereof. The present invention also relates to methods for treating an ophthalmological disease, disorder, and/or condition in a subject with high-risk drusen, comprising administration of an effective amount of an anti-C 5 agent or a pharmaceutically acceptable salt thereof.

Abstract: In one aspect, the disclosure relates to relates to compositions, devices, and processes for drug delivery to an eye. The disclosed drug delivery compositions comprise a particle having a core component comprising a first polymer and a therapeutic agent, and a shell layer surrounding the core component comprising a second polymer. In a further aspect, the present disclosure relates to methods of treating an ophthalmological disease or disorder. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: The invention provides compositions and methods for the treatment of presbyopia. The compositions comprise aceclidine hydrochloride, polysorbate 80, mannitol, anhydrous hypromellose, disodium edetate dihydrate, benzalkonium chloride, sorbic acid and anhydrous sodium citrate and optionally tropicamide.

Abstract: The invention provides a pharmaceutical composition for use in the prevention or therapy of glaucoma, increased intraocular pressure, ocular hypertension and/or a symptom associated therewith, wherein—the composition comprises latanoprost and a liquid vehicle comprising a semifluorinated alkane; and—the composition is administered to the eye of a subject; and—the amount of latanoprost administered in a single dose per eye is in the range of from about 0.5 to 1.4 ?g.

Abstract: Provided herein are drug dosage forms having a swellable component, which alone or in conjugation with one or more other components of the drug dosage forms expand the overall size of the drug dosage form in the stomach. The drug dosage forms are configured to be retained in the stomach for an extended period of time based on this increase in size of the drug dosage form in the stomach (e.g., retained in the stomach for a period of at least about 24 hours). The drug dosage forms described herein are formulated to release a drug during at least a portion of the stomach residency period. In other aspects, also provided are methods of designing, methods of making, such as using three-dimensional printing, and methods of delivering a drug to an individual, wherein such methods are associated with the drug dosage forms described herein.