Patents Issued in January 2, 2024
  • Patent number: 11857290
    Abstract: The invention relates to a device (1) for endoscopic optoacoustic imaging comprising an imaging unit (2) configured to be at least partially inserted into an object (5), said imaging unit (2) comprising an irradiation unit (6) configured to irradiate a region of interest (7) inside the object (5) with electromagnetic radiation and a detection unit (8) comprising at least one ultrasound transducer configured to detect ultrasound waves generated in the region of interest (7) in response to irradiating the region of interest (7) with the electromagnetic radiation and to generate according detection signals, wherein the at least one ultrasound transducer exhibits a field of view (8b) being at least partially located in the irradiated region of interest (7).
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: January 2, 2024
    Assignee: Helmholtz Zentrum Munchen Deutsches Forschungszentrum Fur Gesundheit und Umwelt (GmbH)
    Inventors: Vasilis Ntziachristos, George Sergiadis, Christian Zakian, Andreas Buehler
  • Patent number: 11857291
    Abstract: Disclosed is the electronic architecture, including component arrangement and use of switches, and power saving method for use in a dual mode USTA instrumentation. In an embodiment, the instrument architecture includes US and TA analog components, including a transducer, TA preamplifier, pulser, switches, and AFE (or ADC with programmable amplifier) arranged in a way which allows efficient usage of the same transducer elements, electronic components, wiring, and AFE channels in both US and TA modalities. The operation with fast power control over the TA preamplifier is described, which allows turning off the TA preamplifier power between TA measurements cycles with or without US measurement between TA measurements. TA preamplifier energy saving allows such designs to reduce TA preamplifier power consumption many times, which enables TA preamplifier integration inside transducer housing or probe housing, and/or the use of the TA preamplifier in portable battery-operated or hand-held devices.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: January 2, 2024
    Assignee: PhotoSound Technologies Inc.
    Inventors: Vassili Ivanov, Sergey A. Ermilov
  • Patent number: 11857292
    Abstract: Disclosed are a method for diagnosing a vascular disease and an apparatus therefor. A vascular disease diagnosing method according to an exemplary embodiment of the present disclosure includes: an information acquiring step of acquiring patient information for a diagnosis subject; an FFR processing step of applying a geometric feature parameter information generated based on the patient information to a first learning model to calculate fractional flow reserve (FFR) information; a CFD processing step of applying the geometric feature parameter information to computational fluid dynamics (CFD) to calculate flow feature information; and a diagnosing step of determining a vascular disease based on the fractional flow reserve information and the flow feature information and determine whether to perform a surgery on the vascular disease.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: January 2, 2024
    Assignee: E8IGHT Co., Ltd.
    Inventors: Joon Sang Lee, Young Woo Kim
  • Patent number: 11857293
    Abstract: Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patent is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding before, during, and after fluid resuscitation, in some instances, in real-time.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: January 2, 2024
    Inventors: Isobel Jane Mulligan, Gregory Zlatko Grudic, Steven L. Moulton
  • Patent number: 11857294
    Abstract: Provided herein are medical devices, systems and platforms to monitor tissue properties such as oxygen saturation, temperature and degree of tissue edema for diagnosis and post-operative patient monitoring. The medical devices may be handheld or portable or may be removable patches. The medical devices utilize light of various visible and near-infrared wavelengths to interrogate a tissue where the intensities of reflected light correlate to one or more tissue property. Also provided are methods for measuring tissue properties, for detecting pressure ulcers and for remotely monitoring in real time a surgical flap on a post-operative subject via the medical devices.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: January 2, 2024
    Assignee: The Texas A&M University System
    Inventors: John Hanks, Amir Tofighi Zavareh, Michel Saint-Cyr
  • Patent number: 11857295
    Abstract: An adapter includes a substantially rigid body having a distal portion, a proximal portion, a central opening formed at least in part by an inner wall of the body, and a longitudinal axis extending substantially centrally through the opening. The distal portion includes an annular ring having a top surface and a ridge disposed opposite the top surface, the ridge extending substantially perpendicular to the longitudinal axis. The distal. The adapter also includes a seal configured to form a substantially fluid-tight seal with a surface of a fitting removably attachable to the adapter.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: January 2, 2024
    Assignee: WELCH ALLYN, INC.
    Inventors: Sean R. Karla, Raymond A. Lia, Scott A. Martin, Robert L Vivenzio, Thaddeus J. Wawro, Chris R. Roberts, Jeffrey J. Perkins
  • Patent number: 11857296
    Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: January 2, 2024
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Justin Davies, Joseph Burnett, Howard David Alpert
  • Patent number: 11857297
    Abstract: Systems, devices, and methods are described herein for ensuring constant contact of a physiological sensor with a subject. A device may include a wearable band wearable by the subject, an elastic coupling member, a sensor module coupled by the elastic coupling member to the wearable band, a housing attached to the wearable band, a processor, and a user interface. The wearable band may include a recess extending into the wearable band. The elastic coupling member and/or the sensor module may be disposed within the recess. As the subject wears the wearable band, the elastic coupling member may press the sensor module against the subject and may cause constant contact between the sensor module and the subject. Electrical tracing embedded in the wearable band and extending from the sensor module to the housing may couple the sensor module to the processor or the user interface.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: January 2, 2024
    Assignee: Tula Health, Inc.
    Inventors: Josh Williams, Nicole Winter, Spencer Talbot, Mitchell Slater, Devin Miller, Ethan Krause, Thomas A. Naylor, Paul McMullin, Roger Black, Brian Jensen, Cameron Hernandez
  • Patent number: 11857298
    Abstract: A wearable device includes a housing; a wrist band attached to the housing; first and second emitters positioned within the housing and configured to respectively emit, through a back of the housing, a first beam of electromagnetic radiation having a first infrared (IR) wavelength and a second beam of electromagnetic radiation having a second IR wavelength. The second IR wavelength is different from the first IR wavelength. The wearable device also includes a photodetector positioned within the housing and filtered to detect a set of electromagnetic radiation wavelengths including the first IR wavelength and the second IR wavelength; and a matter differentiation circuit configured to indicate, at least partly in response to signals indicating amounts of the first IR wavelength and the second IR wavelength received by the photodetector, whether the back of the housing is likely proximate to human tissue.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: January 2, 2024
    Assignee: Apple Inc.
    Inventors: Nicholas P. Allec, Albert E. Cerussi, Maximillian C. Bruggeman, Xiyu Duan, Ueyn L. Block
  • Patent number: 11857299
    Abstract: A wearable heart activity sensor device includes a substrate of optically transparent material arranged to face a skin of a user when the sensor device is worn by the user, at least one light emitting diode, LED, arranged on the substrate and arranged to emit light through the substrate, at least one photo sensor arranged on the substrate as spatially separated from the at least one LED and arranged to absorb light through the substrate, wherein the at least one LED and the at least one photo sensor are included in a photoplethysmogram sensor of the heart activity sensor device, and an overmold of thermoplastic material covering the at least one light emitting diode, the at least one photo sensor and a space between the at least one light emitting diode and the at least one photo sensor.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: January 2, 2024
    Assignee: Polar Electro Oy
    Inventors: Veli-Pekka Putila, Elias Pekonen
  • Patent number: 11857300
    Abstract: Radio frequency motion sensors may be configured for operation in a common vicinity so as to reduce interference. In some versions, interference may be reduced by timing and/or frequency synchronization. In some versions, a master radio frequency motion sensor may transmit a first radio frequency (RF) signal. A slave radio frequency motion sensor may determine a second radio frequency signal which minimizes interference with the first RF frequency. In some versions, interference may be reduced with additional transmission adjustments such as pulse width reduction or frequency and/or timing dithering differences. In some versions, apparatus may be configured with multiple sensors in a configuration to emit the radio frequency signals in different directions to mitigate interference between emitted pulses from the radio frequency motion sensors.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: January 2, 2024
    Inventors: Stephen McMahon, Przemyslaw Szkot, Redmond Shouldice
  • Patent number: 11857301
    Abstract: Systems are provided for detecting the flow of blood in vasculature by illuminating the blood with a source of coherent illumination and detecting one or more time-varying properties of a light speckle pattern that results from the scattering of the coherent illumination by tissue and blood. The movement of blood cells and other light-scattering elements in the blood causes transient, short-duration changes in the speckle pattern. High-frequency sampling or other high-bandwidth processing of a detected intensity at one or more points in the speckle pattern could be used to determine the flow of blood in the vasculature. Such flow-measuring systems are also presented as wearable devices that can be operated to detect the flow in vasculature of a wearer. Systems and methods provided herein can additionally be applied to measure flow in other scattering fluid media, for example in a scattering industrial, medical, pharmaceutical, or environmental fluid.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: January 2, 2024
    Assignee: Verily Life Sciences LLC
    Inventors: Andrew Homyk, Russell Norman Mirov
  • Patent number: 11857302
    Abstract: The invention refers to a method of determining an indicator that is representative for a patient's volume responsiveness, comprising the following steps: (i) measuring a sequence of pulse signals of a patient; (ii) determining an envelope(signal)-curve based on the sequence of measured pulse signals; (iii) determining a fit(envelope(signal))-function based on the previously determined envelope(signal)-curve, the fit(envelope(signal))-function representing an idealised curve progression of the envelope(signal)-curve without comprising pulse variations caused by ventilation or respiration induced heart-lung interaction; (iv) determining respiratory pulse variation signals corresponding to the pulse variations caused by ventilation or respiration induced heart-lung interaction; (v) determining an envelope(respiration)-curve based on the previously determined respiratory pulse variation signals; (vi) determining a fit(envelope(respiration))-function based on the previously determined envelope(respiration)-curve,
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: January 2, 2024
    Assignee: PHILIPS MEDIZIN SYSTEME BÖBLINGEN GMBH
    Inventor: Reinhold Knoll
  • Patent number: 11857303
    Abstract: An apparatus for measuring foot blood flow has a platform with a platform contact surface configured to receive a foot force from a user placing their foot on the contact surface. The apparatus also has a plurality of PPG sets (having at least one light source and at least one detector) extending through the platform contact surface, and a plurality of springs. Each PPG set is coupled with one or more of the springs to movably couple with the platform. In addition, each spring is biased to produce a biasing force via its coupled PPG set when the contact surface of the platform receives the foot. To maintain consistent pressure against the skin and good signal to noise ratio, each PPG set and its corresponding one or more springs are configured so that the biasing force has a magnitude that is substantially independent of the foot force magnitude.
    Type: Grant
    Filed: December 6, 2022
    Date of Patent: January 2, 2024
    Assignee: Podimetrics, Inc.
    Inventors: David Linders, Zoe Wolszon, Jacob O'Brien, Madeline Diane Rogers, Lauren O'Neil Grove, Dennis Lan-Bo Wei, Emma Grace Lloyd, Heather Gerstley, Benjamin Thomas Centracchio
  • Patent number: 11857304
    Abstract: Data about concentration of one or more types of molecules present within a human body are determined noninvasively using radio frequency signals. These signals generated at very low power levels are emitted and acquired using an antenna mounted to a wearable device. Information about changes to the signals is indicative of the concentration of one or more types of molecules within the user. The antenna includes two or more elements with a varying distance between them which reduces or eliminates power reflection and improves overall efficiency. The varying distance provides a first impedance at terminals of the antenna and a second impedance elsewhere on the antenna, such as midway along a long axis of the antenna. The first impedance matches an impedance of a transmitter output, a receiver input, or both. The second impedance results in the signal extending away from the antenna towards the user.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: January 2, 2024
    Assignee: AMAZON TECHNOLOGIES, INC.
    Inventor: Leo Benedict Baldwin
  • Patent number: 11857305
    Abstract: Disclosed is a system for detecting an internal object in a body. The system includes at least one antenna pair including two antennas which are adapted to be symmetrically positioned around the body in relation to a line of symmetry. The system is adapted to transmit microwave signal into the body which are reflected and/or scattered from the internal object. The system is adapted to receive the reflected and/or scattered microwave signals, and to compare the received microwave signals at the symmetrically positioned antennas. The system is adapted to detect the internal object or a change in an already detected internal object when there is a difference between the received microwave signals at symmetric antenna pairs. The difference is related to the different dielectric properties between the internal object and the body.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: January 2, 2024
    Assignee: MEDFIELD DIAGNOSTICS AB
    Inventors: Andreas Fhager, Mikael Persson, Harald Jacobsson, Rikard Vinge
  • Patent number: 11857306
    Abstract: A method of obtaining multiple MRI contrasts of a subject comprising the steps of concurrently acquiring an MRSI and fMRI data in the same scan.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: January 2, 2024
    Assignee: UNM Rainforest Innovations
    Inventor: Stefan Posse
  • Patent number: 11857307
    Abstract: A probe generates location signals, and has an electrode at a distal end that acquires from heart chamber surface positions electrical signals due to a conduction wave traversing the surface. A processor derives LATs from the electrical signals, calculates a first time difference between LATs at a first pair of positions and a second time difference between LATs at a second pair of positions. The processor calculates first and second LAT-derived distances as products of the first and second time differences with a conduction wave velocity, identifies an arrhythmia origin at a surface location where a first difference in distances from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances from the location to the second pair of the positions is equal to the second LAT-derived distance, and marks the origin on a surface representation.
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: January 2, 2024
    Assignees: BIOSENSE WEBSTER (ISRAEL) LTD., RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Gal Hayam, Michael Timofeyev, Tal Haim Bar-On, Amardeep Saluja
  • Patent number: 11857308
    Abstract: A system for respiratory monitoring of a subject comprises: a bioimpedance measurement sensor, which is configured for arrangement in relation to the subject for acquiring a bioimpedance signal; a processing unit, which is configured to receive the acquired bioimpedance signal and receive a reference signal, the reference signal representing a respiratory effort of the subject or a respiratory airflow at a time of bioimpedance signal acquirement, the processing unit being further configured to divide the bioimpedance signal into an effort component representing a respiratory effort of the subject and a flow component representing a respiratory airflow of the subject based on the received bioimpedance signal and the received reference signal.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: January 2, 2024
    Assignee: STICHTING IMEC NEDERLAND
    Inventors: Willemijn Groenendaal, Ruben De Francisco Martin
  • Patent number: 11857309
    Abstract: Embodiments of the present disclosure provide respiration monitoring systems and methods for using same. The respiration monitoring device can include a first accelerometer, a second accelerometer, at least one acoustic sensor, a memory comprising a lookup table, a real-time clock, and one or more instructions, and a processor for receiving one or more motion signals from each accelerometer and one or more sound signals from each acoustic sensor. The processor can correlate the one or more motion signals to a distance value, correlate the one or more sound signals to a sound value, filter the distance value and the sound value according to limitations stored in the lookup table, assign a time stamp to each filtered value, determine local maximums for the filtered motion values and local minimums for the filtered sound values, and match the local maximums to the local minimums to confirm a completed breath.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: January 2, 2024
    Inventor: Casey Marie Campbell
  • Patent number: 11857310
    Abstract: A physiological parameter processing apparatus includes an input interface section that acquires respiration data produced based on a respiratory gas that is obtained from at least one of a mouth and nose of a subject, and an analyzing section that analyzes in real time the respiration data acquired through the input interface section, and that produces analysis result data which can be displayed in real time.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: January 2, 2024
    Assignee: NIHON KOHDEN CORPORATION
    Inventors: Hironori Kobayashi, Yukio Nonaka, Kazuri Higashi, Takayuki Sugiyama
  • Patent number: 11857311
    Abstract: The multi-purpose video monitoring camera includes a microprocessor, a CMOS video camera, a thermographic video camera, a display unit and a mic array. The microprocessor includes a baby presence detection module, a warning module, a motion detection module, a breathing detection module, a hot air exhalation detection module, a chest movement detection module, a breathing sound detection module, a suffocation detection module, a temperature measurement module, a urination and defecation detection module, an air conditioning module and a baby growth rate module. By using inputs from both the CMOS video camera and the thermographic video camera, the accuracy of the baby presence detection module is improved.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: January 2, 2024
    Inventor: Wai Hung Lee
  • Patent number: 11857312
    Abstract: Embodiments generally relate to a method of assessing the hearing of a patient using functional near-infrared spectroscopy (fNIRS). The method comprises receiving at least one response signal from an optode placed on a scalp of the patient, the response signal comprising fNIRS data generated by the optode and relating to an aural stimulation received by the patient; comparing at least one parameter of the at least one response signal to a predetermined parameter value; and determining an auditory response of a patient based on the at least one parameter of the at least one response signal.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: January 2, 2024
    Assignee: THE BIONICS INSTITUTE OF AUSTRALIA
    Inventors: Colette McKay, Hamish Innes-Brown, Mehrnaz Shoushtarian, Stefan Weder
  • Patent number: 11857313
    Abstract: A system 100, 200 for sensing one or more analytes in a first biofluid and a second biofluid and methods of using said system. The system 100, 200 may include a first subsystem 102, 200a, 200b with a first sensor 120, 122, 220, 222 for sensing a first analyte in the first biofluid and a second subsystem 104, 200b, 200c with a second sensor 124, 126, 222, 224 for sensing a second analyte in the second biofluid. The second analyte may be the same as or different from the first analyte and the second biofluid may be different from the first biofluid. In an embodiment, the first biofluid is a non-sweat biofluid and the second biofluid is sweat. The system 100, 200 may be used to detect lag time for measuring an analyte in one of the biofluids.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: January 2, 2024
    Assignee: University of Cincinnati
    Inventor: Jason C. Heikenfeld
  • Patent number: 11857314
    Abstract: A method of managing insulin includes receiving blood glucose measurements on a computing device from a glucometer. The blood glucose measurements are separated by a time interval. The method includes determining, by the computing device, an insulin dose rate based on the blood glucose measurements and determining a blood glucose drop rate based on the blood glucose measurements and the time interval. The method also includes determining a blood glucose percentage drop based on the blood glucose measurements. The method includes decreasing the time interval between blood glucose measurements by the glucometer when the blood glucose drop rate is greater than a threshold drop rate, and decreasing the time interval between blood glucose measurements by the glucometer when the blood glucose percentage drop is greater than a threshold percentage drop.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: January 2, 2024
    Assignee: Aseko, Inc.
    Inventors: Robert C. Booth, Harry Hebblewhite
  • Patent number: 11857315
    Abstract: A system and method to help maintain quality control and reduce cannibalization of accessories and attached probes in a highly sensitive patient monitor, such as a pulse oximetry system. One or more attached components may have information elements designed to designate what quality control mechanisms a patient monitor should look to find on that or another component or designate other components with which the one component may properly work. In a further embodiment, such information elements may also include data indicating the appropriate life of the component.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: January 2, 2024
    Assignee: MASIMO CORPORATION
    Inventor: Ammar Al-Ali
  • Patent number: 11857316
    Abstract: In a non-invasive optical detection system and method, sample light is delivered into a scattering medium. A first portion of the sample light passing through a volume of interest exits the scattering medium as signal light, and a second portion of the sample light passing through a volume of non-interest exits the scattering medium as background light that is combined with the signal light to create a sample light pattern. Reference light is combined with the sample light pattern to create an interference light pattern having a holographic beat component. Ultrasound is emitted into the volume of non-interest in a manner that decorrelates the background light of the sample light pattern from the holographic beat component. The holographic beat component is detected during the measurement period. An optical parameter of the volume of interest is determined based on the detected holographic beat component.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: January 2, 2024
    Assignee: HI LLC
    Inventors: Jamu Alford, Ashutosh Chaturvedi, Adam Marblestone
  • Patent number: 11857317
    Abstract: An imaging system, such as a surgical microscope, laparoscope, or endoscope or integrated with these devices, includes an illuminator providing patterned white light and/or fluorescent stimulus light. The system receives and images light hyperspectrally, in embodiments using a hyperspectral imaging array, and/or using narrowband tunable filters for passing filtered received light to an imager. Embodiments may construct a 3-D surface model from stereo images, and will estimate optical properties of the target using images taken in patterned light or using other approximations obtained from white light exposures. Hyperspectral images taken under stimulus light are displayed as fluorescent images, and corrected for optical properties of tissue to provide quantitative maps of fluorophore concentration. Spectral information from hyperspectral images is processed to provide depth of fluorophore below the tissue surface. Quantitative images of fluorescence at depth are also prepared.
    Type: Grant
    Filed: October 6, 2022
    Date of Patent: January 2, 2024
    Assignees: THE TRUSTEES OF DARTMOUTH COLLEGE, UNIVERSITY HEALTH NETWORK
    Inventors: Pablo Valdes, Frederic Leblond, Keith D. Paulsen, Brian Campbell Wilson, David W. Roberts, Michael Jermyn
  • Patent number: 11857318
    Abstract: The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: January 2, 2024
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Tzung K. Hsiai, Yu-Chong Tai, Rene R. Sevag Packard, Yuan Luo, Parinaz Abiri, Jianguo Ma
  • Patent number: 11857319
    Abstract: Aspects of the present disclosure include a sensor configured to store in memory indications of sensor use information and formulas or indications of formulas for determining the useful life of a sensor from the indications of sensor use information. A monitor connected to the sensor monitors sensor use and stores indications of the use on sensor memory. The monitor and/or sensor compute the useful life of the sensor from the indications of use and the formulas. When the useful life of the sensor is reached, an indication is given to replace the sensor.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: January 2, 2024
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, Walter M. Weber, Ryan Timothy McHale
  • Patent number: 11857320
    Abstract: A blood sequestration device configured to isolate an initial, potentially contaminated portion of blood from the flow of blood of a patient, prior to directing the flow of blood to an outlet port where the blood can be accessed. The blood sequestration device including a body member having an interior wall defining a fluid conduit having a distal portion, a first proximal portion, and a second proximal portion, wherein the first proximal portion defines a sequestration chamber configured to isolate an initial portion of blood of a flow of blood, a vent path configured to enable the escape of gas initially trapped within the sequestration chamber.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: January 2, 2024
    Assignee: Smiths Medical ASD, Inc.
    Inventors: Jeffrey Scott Langdell, Jay T. Breindel, Harsh D. Chheda
  • Patent number: 11857321
    Abstract: An apparatus for procuring bodily fluid samples with reduced contamination includes a housing having a sequestration chamber, an inlet, and an outlet. A flow controller defines a portion of the sequestration chamber and can transition—in response to a suction force exerted by a fluid collection device fluidically coupled to the outlet—from a first state in which the sequestration chamber has a first volume to a second state in which the sequestration chamber has a second volume greater than the first volume, to draw an initial volume of bodily fluid into the sequestration chamber. An actuator is coupled to the housing and is in fluid communication with the inlet and the sequestration chamber in a first configuration, and is transitioned to a second configuration to sequester the sequestration chamber from the inlet, and allow a subsequent volume of bodily fluid to flow from the inlet to the outlet.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: January 2, 2024
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Jay M. Miazga, Timothy F. Ramsey, Abigail Patterson
  • Patent number: 11857322
    Abstract: A system includes a display device, a user interface, a memory, and a control system. The memory contains machine readable medium including machine executable code storing instructions for performing a method. The control system is coupled to the memory, and includes one or more processors. The control system is configured to execute the machine executable code to cause the control system to display, on the display device, a series of questions from mental health questionnaires. The series of questions includes text and answers for each question. From the user interface, a selection of answers of each of the displayed series of questions is received from a patient. Using a Bayesian Decision List, the received selection of answers is processed to output an indication of mental health of the patient. The indication of mental health identifies a kappa opioid receptor antagonist to which the patient would likely be a higher responder.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: January 2, 2024
    Assignee: NEUMORA THERAPEUTICS, INC.
    Inventors: Qingzhu Gao, Humberto Andres Gonzalez Cabezas, Parvez Ahammad, Yuelu Liu
  • Patent number: 11857323
    Abstract: A system and method for camera-based stress determination. The method includes: determining a plurality of regions-of-interest (ROIs) of a body part; determining a set of bitplanes in a captured image sequence for each ROI that represent HC changes using a trained machine learning model, the machine learning model trained with a hemoglobin concentration (HC) changes training set, the HC changes training set trained using bitplanes from previously captured image sequences of other human individuals as input and received cardiovascular data as targets; determining an HC change signal for each of the ROIs based on changes in the set of determined bitplanes; for each ROI, determining intervals between heartbeats based on peaks in the HC change signal; determining heart rate variability using the intervals between heartbeats; determining a stress level using at least one determination of a standard deviation of the heart rate variability; and outputting the stress level.
    Type: Grant
    Filed: September 15, 2022
    Date of Patent: January 2, 2024
    Assignee: NURALOGIX CORPORATION
    Inventors: Kang Lee, Pu Zheng, Si Wu
  • Patent number: 11857324
    Abstract: A system for monitoring the operational status of an aircraft crew includes a unit for determining at least one pilot state based on first monitoring data of a high design assurance level and second monitoring data of a lower design assurance level. The determination unit includes a first evaluation module capable of obtaining a high-level pilot state from the first data, regardless of the second data; a second evaluation module capable of determining a low-level pilot state, from at least the second data; and a consolidation module for determining a consolidated pilot state. The consolidated pilot state is obtained as a function of the high-level pilot state and the low-level pilot state.
    Type: Grant
    Filed: February 19, 2022
    Date of Patent: January 2, 2024
    Assignee: DASSAULT AVIATION
    Inventors: François Salmon-Legagneur, Valentin Ligier, Cyril Saint Requier
  • Patent number: 11857325
    Abstract: A device for communicating a driving ability level of a user, the device comprising at least a processor, a memory, and a wireless transceiver. The device is configured to: receive a communication from a medical device, wherein the communication comprises information relating to a condition of the medical device; and send a communication to a vehicle. The information relating to a condition of the medical device is processed in order to determine a driving ability level of the user by the assignment of a category selected from a group comprising a first category and a second category.
    Type: Grant
    Filed: August 3, 2022
    Date of Patent: January 2, 2024
    Assignee: Sanofi
    Inventor: Michael Helmer
  • Patent number: 11857326
    Abstract: Provided herein are a variety of neural probe devices that include an agent delivery feature via an agent coating or an agent delivery mechanism of some kind. The probe devices can include depth or cortical probes or electrodes. The agent delivery mechanisms can include, for example, a dissolvable agent delivery structure, an agent delivery lumen, a magnetically deployable cover, an iontophoretic delivery mechanism, an agent delivery cavity defined in the neural probe, or an agent reservoir with an actuable gate.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: January 2, 2024
    Assignee: NeuroOne Medical Technologies Corporation
    Inventors: Dave Rosa, Thomas Bachinski
  • Patent number: 11857327
    Abstract: A non-invasive bodily-attached ambulatory medical monitoring and treatment device with pacing is provided. The noninvasive ambulatory pacing device includes a battery, at least one therapy electrode coupled to the battery, a memory storing information indicative of a patient's cardiac activity, and at least one processor coupled to the memory and the at least one therapy electrode. The at least one processor is configured to identify a cardiac arrhythmia within the information and execute at least one pacing routine to treat the identified cardiac arrhythmia.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: January 2, 2024
    Assignee: ZOLL Medical Corporation
    Inventors: Jason T. Whiting, Thomas E. Kaib, Rachel H. Carlson, Gregory R. Frank
  • Patent number: 11857328
    Abstract: An active electrode has an electrode for sensing an electric potential and generating an input signal, and a shield placed near the electrode but being electric insulated from the electrode. An integrated amplifier (10) has an input connected to the at least one electrode for receiving the input signal, and providing a buffered path outputting a buffered output signal. The shield being connected to the output of the integrated amplifier to actively drive the electrical potential of the shield, thereby providing an active shielding of the electrode. The buffered path includes a first mixer (11) in front of the integrated amplifier for frequency shifting the input signal from a basic frequency range to a higher frequency range, and a second mixer (12) on the output of the integrated amplifier for frequency shifting the amplified signal from the higher frequency range back to the basic frequency range. The active electrode may be used for recording EEG signals.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: January 2, 2024
    Assignee: T&W Engineering A/S
    Inventors: Preben Kidmose, Xiong Zhou, Soren Kilsgaard, Qiang Li
  • Patent number: 11857329
    Abstract: A cardiac monitoring and treatment system includes a controller, a first wearable portion, and a second wearable portion separate from the first wearable portion. The first wearable portion includes an elongated strap configured to encircle a thoracic region of a patient, a plurality of ECG sensing electrodes disposed about the elongated strap, one or more receiving ports configured to receive one or more additional components including a treatment electrode and/or an additional sensor, and a plurality of conductive wires configured to couple the plurality of ECG sensing electrodes and the one or more receiving ports with the controller. The second wearable portion is configured to be worn over at least one shoulder of the patient and includes a wearable substrate, one or more treatment electrodes disposed on the wearable substrate, and at least one conductive wire configured to releasably connect the one or more treatment electrodes to the controller.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: January 2, 2024
    Assignee: ZOLL Medical Corporation
    Inventors: Michael J Gabrin, Christopher L Swenglish, Gary A Freeman
  • Patent number: 11857330
    Abstract: Provided herein are systems, kits, and methods for monitoring brain activity. In some implementations, a system includes a plurality of wearable sensors having a housing with an extended, rounded shape are removably attached to the scalp of a patient and monitor electroencephalogram (EEG) signals. Approaches for instructing a user to position and active that wearable sensors are disclosed. Approaches for facilitating collection, synchronization, and processing of EEG signals are disclosed. Approaches for handing off control of the wearable sensors between portable computing devices are disclosed.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: January 2, 2024
    Assignee: Epitel, Inc.
    Inventors: Mitchell A. Frankel, Robert Lingstuyl, Michael K. Elwood, Mark J. Lehmkuhle
  • Patent number: 11857331
    Abstract: A force measurement system is disclosed herein. The force measurement system includes at least one user input device, a force measurement assembly configured to receive a subject, at least one visual display device, and one or more data processing devices operatively coupled to the user input device, the force measurement assembly, and the visual display device. The one or more data processing devices being programmed to receive the one or more input signals from the user input device based upon one or more selections by the user, the one or more selections including a scene movement setting and a force measurement assembly movement setting; display the one or more scenes on the output screen of the at least one visual display based upon the scene movement setting selected by the user; and control the force measurement assembly based upon the force measurement assembly movement setting selected by the user.
    Type: Grant
    Filed: January 2, 2023
    Date of Patent: January 2, 2024
    Assignee: Bertec Corporation
    Inventors: Necip Berme, Aysun Gokoglu
  • Patent number: 11857332
    Abstract: An arrangement for determining a degree of stretching of hair is provided. The arrangement includes a detection unit for detecting hair characteristics and an evaluation unit for evaluating the detected hair characteristics and for determining the degree of elongation of hair based on the detected hair characteristics. The detection unit contains a near-infrared sensor, and is configured to irradiate a hair sample with electromagnetic waves in the infrared range and to detect an absorbance of the hair sample in a wavelength range from about 800 to about 2500 nm. The acquisition unit is configured to generate an absorption spectrum of the hair sample in the wavelength range of from about 800 to about 2500 nm and provide it to the evaluation unit and the evaluation unit is configured to compare the generated absorption spectrum with a calibration model and to determine a degree of elongation of the hair sample.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: January 2, 2024
    Assignee: HENKEL AG & CO. KGAA
    Inventors: Hans Georg Knuebel, Lucile Bonnin, Astrid Kroos, Annika Koenen, Erik Schulze Zur Wiesche
  • Patent number: 11857333
    Abstract: The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: January 2, 2024
    Assignee: Cleveland Medical Devices Inc.
    Inventors: Hani Kayyali, Dan Bishop, Brian M. Kolkowski
  • Patent number: 11857334
    Abstract: Systems and methods for monitoring a subject under, or suspected to be under, the influence of one or more drugs are provided. In one aspect, a method comprises controlling one or more sensors of a monitoring device to acquire physiological signals from a subject suspected to be under the influence of one or more drugs, and assembling a set of physiological data using the acquired physiological signals. The method also includes generating, using a processor of the monitoring device, physiological markers characteristic of the influence of the one or more drugs by analyzing the set of physiological data, and correlating the physiological markers with a drug profile characterizing the one or more drugs affecting the subject. The method further includes proving to a user a report indicating the drug profile characterizing the one or more drugs affecting the subject.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: January 2, 2024
    Assignee: The General Hospital Corporation
    Inventors: Jacob A Donoghue, Kathleen J. Koenigs, Patrick L Purdon, Emery N. Brown
  • Patent number: 11857335
    Abstract: Systems, methods and apparatuses for rehabilitation and/or training of a subject. Rehabilitation may be performed after neurological damage has occurred, including without limitation acute or chronic damage. Training as referred to herein relates to any process performed in order to improve the physical and/or cognitive function of a subject.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: January 2, 2024
    Assignee: MINDMAZE GROUP SA
    Inventors: Tej Tadi, Nicolas Fremaux, Jose Rubio, Jonas Ostlund, Sebastien Lasserre, Léandre Bolomey
  • Patent number: 11857336
    Abstract: Arousal events can be determined for a user associated with a wearable device, such as a user wearing a wearable computing device including one or more sensors. The one or more sensors may obtain EDA information that may determine a sympathetic nervous system response of the user, which may be responsive to an arousal event or an activation. Detection of events that increase the EDA response may provide information to the user regarding arousal events and provide recommendations to the user to address the arousal events to decrease their response.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: January 2, 2024
    Assignee: FITBIT LLC
    Inventors: Man-Chi Liu, Alexander Statan, Derrick Steven Vickers, Paul Francis Stetson, Elena Perez, James Horng-Kuang Lin, Belen Lafon, Lindsey Michelle Sunden
  • Patent number: 11857337
    Abstract: A method, system, apparatus, and/or device for adjusting a power consumption level of a device. The method, system, apparatus, and/or device may include: a first sensor interface, a second sensor interface, and a processing device coupled to the first sensor interface and the second sensor interface. The processing device may: measure a first physiological measurement via the first sensor interface within a first period of time; measure a second physiological measurement via the second sensor interface within the first period of time; adjust a power consumption level of the apparatus in view of at least one of the first physiological measurement or the second physiological measurement; measure the physiological measurement via the first sensor interface at the adjusted power consumption level within a second period of time; and measure a second physiological measurement via the second sensor interface at the adjusted power consumption level within the second period of time.
    Type: Grant
    Filed: December 7, 2022
    Date of Patent: January 2, 2024
    Assignee: Tula Health, Inc.
    Inventors: Devin W. Miller, David R. Miller
  • Patent number: 11857338
    Abstract: The invention relates to a system for analysing physico-chemical properties of a skin surface, comprising: at least one contact sensor for applying to said skin surface to be analysed in order to determine specific information, once or twice a day, about a particular area of the skin surface; at least one environment sensor designed to accompany a user throughout the day and to measure, throughout the day, at least one external parameter acting on said skin surface; and a processing unit interfaced with the contact and environment sensors, said unit being fitted with analysis means allowing the determination of physico-chemical properties of the skin surface to be analysed, from signals generated by the contact and environment sensors.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: January 2, 2024
    Assignee: IEVA
    Inventor: Yann Treguer
  • Patent number: 11857339
    Abstract: Disclosed is a headgear-type device for hazardous air quality warning and air quality improvement, wherein the device can collect biometric information of a worker, wired and wireless communications, and information about the quality of outside air around the worker so as to warn the worker of a hazard or improve air quality at the site.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: January 2, 2024
    Assignee: LEESTECH SYSTEM CO., LTD.
    Inventors: Jae Hong Lee, Soon Wi Kim, Won Sik Lee, Hyun Sik Lee, Na Young Lee, Soon Hyang Lee