Abstract: Some embodiments of a manifold pad may be configured to distribute reduced pressure relative to a tissue site and to provide instillation to the tissue site. In some embodiments, the manifold pad may comprise open-cell foam and at least one skinned channel extending through the open-cell foam. The at least one skinned channel may be configured so that the skin is substantially impermeable to liquid, preventing liquid within the channel from seeping into the open-cell foam. In some embodiments, this may allow for two isolated pathways for fluid movement through the manifold pad. Some dressing embodiments may utilize such a manifold pad in conjunction with a treatment device. Other apparatus, dressings, systems, and methods are disclosed.

Abstract: Disclosed is an infusion line indication system that includes one or more indicator devices configured for attachment to a medical line such as an infusion line, and a dongle that is connectable to a line control unit such as an infusion line pump. The one or more indicator devices are configured to provide an indicator signal such as a light signal. The dongle and the one or more indicator devices are capable of being wirelessly connected. The dongle is configured to transmit an indicator instruction to the one or more indicator devices in response to one or more line parameters sensed by sensors of the indicator devices or by the line control unit to thereby cause the indicator signal to change.

Abstract: Provided herein is a system for sequential delivery of therapeutic compositions, including a first fluid source and a second fluid source, one or more first sensors associated with each of the first fluid source and the second fluid source, an actuator-actuated valve, and a processor in communication with the one or more sensors, wherein the processor is programmed or configured to control, based on data received from the one or more sensors, the actuator-actuated valve to stop and/or cause delivery of therapeutic compositions from the fluid sources.

Abstract: A fluid management and medical device system may include a fluid management system and a medical device. The fluid management system may include a pump configured to pump fluid to the medical device and a processing device configured to control the pump to maintain a target fluid flow range. The medical device may include an elongate shaft in fluid communication with the pump of the fluid management system, a pressure sensor, and a workstation in electronic communication with the pressure sensor and the processing device of the fluid management system. The processing device may be configured to adjust a fluid flow rate based on data received from the pressure sensor of the medical device and configured to verify the medical device is in a patient's body prior to adjusting the fluid flow rate based on the data received from the pressure sensor.

Abstract: Compensation of pressure driven leakage while using high precision volumetric pumps may be provided. A measurement apparatus comprising a pump may be calibrated. Calibrating the measurement apparatus may comprise creating a characterization of leakage through the pump as a function of a pressure difference over the pump. The measurement apparatus may be operated for a predetermined time period to pump a liquid. A measurement of a flow through the measurement apparatus may be determined based on the amount of rotation of the piston. The measurement of the flow may be compensated for leakage of the pump while the measurement apparatus operated for the predetermined time period based on the characterization of leakage and the amount of piston rotation during the period and the monitored pressure difference over the pump.

Abstract: Methods and systems are disclosed wherein temperature in a device such as an ambulatory infusion pump is monitored during inductive charging of the device such that temperature-sensitive contents or components, such as, for example, insulin, particular circuitry and/or other components are not damaged. Temperature can be monitored in the device at one or more locations during inductive charging. If the temperature breaches one or more predetermined thresholds and/or is rising at a rate greater than one or more predetermined thresholds, charging can be suspended or provided at reduced power to prevent the temperature from further rising and damaging the contents and/or components of the device. One or more alerts associated with these events may also be triggered so that the user is aware of the situation and may take corrective action.

Abstract: Disclosed herein is a system and method for calculating an expected peak blood glucose level of user during a post-prandial period, based on a quantity of carbohydrates to be ingested. The user's expected peak blood glucose levels for slow, medium and fast acting carbohydrates are calculated. The results are presented to the user to allow the user to make an informed decision regarding the type of meal to be ingested.

Abstract: A device for subcutaneous delivery of a medicament includes a delivery module to house a cartridge containing a medicament to be delivered to a patient via a needle and a control module coupled to the delivery module to house a control unit and a battery to power the control unit. The delivery module includes an application surface that contacts the patient's body and two opposite first gripping perimeter surfaces extending along a first direction parallel to the application surface and along a second direction perpendicular to the application surface and having substantially equal dimensions in the second direction. The control module includes two opposite second gripping perimeter surfaces extending along the first direction and along the second direction and having substantially equal dimensions in the second direction. The two first gripping perimeter surfaces and the two second gripping perimeter surfaces have substantially equal dimensions in the first direction.

Abstract: Infusion devices having multiple pumping segments connected in parallel to a fluid source and configured to operate together to pump a fluid from the fluid source are described herein. An infusion device includes a first deformable body coupled between the fluid source and an IV set and a second deformable body coupled between the fluid source and the IV set in parallel with the first deformable body. The first deformable body is configured to be hand-compressed and direct a portion of fluid from the first deformable body to an outlet of the IV set for administering the fluid to a patient at a first flow rate. The second deformable body is configured to be hand-compressed and direct another portion of fluid from the second deformable body to the outlet of the IV set for administering the fluid to the patient at a second flow rate.

Abstract: Apparatus, systems, and methods for hemodynamic monitoring are provided. In some embodiments, the hemodynamic monitoring includes use of an IV fluid administered through a blood pressure transducer. The blood pressure transducer generates an electrical signal that is transmitted to a hemodynamic monitor to generate a blood pressure measurement. The blood pressure transducer may comprise a first chamber to receive and transmit an IV fluid, a second chamber connected to a reference tube and filed with reference fluid, and a pressure sensor configured to generate the electrical signal the blood pressure measurement is generated from.

Abstract: A medical device is configured to monitor, using one or more sensors, an environmental condition of a physical environment proximate to a medical device, and to determine when a value representative of the environmental condition exceeds a threshold for safe operation of the medical device with regard to care of a patient. Responsive to the value exceeding the threshold, an operation mode of the medical device is automatically switched from a first mode currently programmed for the care of the patient to a second mode, the second mode using different parameters than the first mode to control the medical device.

Abstract: An integrated intravenous (IV) administration set includes a flow stop having a tubing fitment and a housing, the flow stop configured, in a first position, to prevent a flow of a fluid through the tubing, and in a second position, to permit the flow of the fluid through the tubing, the tubing fitment comprising a protrusion configured to receive a tubing. The IV administration set also includes an electronic flow sensor disposed within the housing, the electronic flow sensor configured to measure a flow of a fluid in the tubing, and one or more conductive connections configured within the housing and configured to provide electrical power to the electronic flow sensor. The flow stop is shaped to be loaded and engaged to a receptacle of an infusion device, and shaped to cause, when loaded and engaged, the one or more conductive connections to engage with a corresponding conductive connection provided by the infusion device to activate the flow sensor based on a power flow from the infusion device.

Abstract: Missed meal bolus reminders or alerts require a user to access the user's pump and/or remote control to clear the reminder/alert even when the user skipped a meal such that no meal bolus was needed. CGM data can be leveraged such that the missed meal bolus alert is only triggered when glucose levels rise in response to consuming the meal within the programmed time window. Therefore, the alert is only provided when a meal is actually consumed and no bolus has been delivered. This further allows the user to be alerted sooner, i.e., as soon as glucose levels rise a predetermined amount or passed a predetermined threshold indicating consumption of a meal as opposed to only at the end of the programmed window.

Abstract: A control device for determining a recommendation value of a control parameter of a fluid infusion device. The control device comprises a retrieving unit configured to retrieve user data, a segmentation unit, the segmentation unit configured to create a plurality of time segments in order to group user data, a segment correction unit configured to create a segment correction value for each time segment and a period correction unit configured to create an updated correction coefficient for a future determined period of time. The control device also comprises a recommendation unit configured to determine the recommendation value.

Abstract: A powerpack sub-assembly for a medicament delivery device is described, the powerpack sub-assembly extending along an axis in an axial direction from a proximal end to a distal end. The powerpack sub-assembly has a housing extending from the distal end of the powerpack sub-assembly, a lock ring slidable in the axial direction relative to the housing, an activation ring slidable in the axial direction relative to the housing and relative to the lock ring, wherein the lock ring is arranged closer to the distal end of the powerpack sub-assembly than the activation ring, a connection mechanism to connect the activation ring to the lock ring during use, the connection mechanism has a connector on the activation ring and a corresponding connector on the lock ring, and a lock mechanism to lock the powerpack sub-assembly after use, the lock mechanism having a distally-facing surface on the lock ring and a corresponding proximally-facing surface on the housing.

Abstract: An autoinjector for dispensing a liquid product, particularly a drug, comprising: an electronic module with a sensor configured to measure the axial movement of a signal element (11) from a position at the start of the dispensing, wherein the signal element (11) is slaved in the dispensing direction, to a position at the end of the dispensing, wherein the signal element (11) strikes the signal stop (12a).

Abstract: An insertion device includes an upper casing, an insertion module and a lower casing. The insertion module is disposed in the upper casing, and includes a main body assembly, an insertion seat, a first elastic member, a retraction seat and a second elastic member. When the upper casing is depressed, the insertion seat is driven by the first elastic member to perform an automatic-insertion operation, such that limiting structure between the insertion seat and the retraction seat collapses upon the collapse of another limiting structure between the insertion seat and the main body assembly, and that the retraction seat is driven by the second elastic member to perform an automatic-retraction operation.

Abstract: Syringe adaptors comprise a hub portion comprising an outer surface, an inner surface, a top surface and a bottom surface, the inner surface configured to receive a portion of a syringe body; and a grip portion. The inner surface may comprise at least one projection.

Abstract: An aspiration and injection device is provided that can allow for ergonomic, safe, and precise aspiration of a target site and ejection of a medicament to the target site. The device can include a syringe barrel, a flange extender couplable to the barrel, and plunger that can be engaged by a hand and/or one or more finger of a user to perform aspiration and injection at a target site.

Abstract: A syringe assembly includes a barrel defining a chamber therein, pressurized sterile air in the chamber, a plunger including a piston slidable in the chamber in a sealing relation to displace a fluid in the chamber, a seal configured to retain the pressurized sterile fluid in the chamber between the piston of the plunger and the seal when the plunger is stationary, and a needle assembly extending distally from the barrel and in fluid communication with the chamber of the barrel.

Abstract: A syringe assembly includes a barrel defining a chamber therein, pressurized sterile air in the chamber, a plunger including a piston slidable in the chamber in a sealing relation to displace a fluid in the chamber, a seal configured to retain the pressurized sterile fluid in the chamber between the piston of the plunger and the seal when the plunger is stationary, and a needle assembly extending distally from the barrel and in fluid communication with the chamber of the barrel.

Abstract: A needle-based device includes a body, a needle protruding from the body, and a needle cap to protect the needle in a first state of disuse of the needle-based device. Also, a needle shield encompasses the needle and at least a partial length of the needle cap in the first state of disuse. A safety cap encompasses the needle cap therewithin. The safety cap is secured onto an outer surface of the needle shield such that the needle and the needle cap are completely protected and covered during the first state of disuse. Guide elements protrude from an end of the needle shield farthest away from the body in the first state of disuse internal to the needle shield such that the needle passes through the guide elements to prevent significant lateral movement of the needle and the needle cap in the first state of disuse.

Abstract: A needle-based device includes a needle shield encompassing an entirety of a length of a needle protruding from a body associated with the needle-based device to protect the needle in a first state of disuse of the needle-based device. The needle shield also includes a lock button with a first end either integrally formed with the needle shield or external to the needle shield and then coupled to the needle shield. The lock button includes a hook at a second end thereof. A length of the lock button is completely external to the needle shield, and the needle shield is locked using the lock button in the first state of disuse of the needle-based device in accordance with the hook of the lock button passing through a groove formed on the needle shield.

Abstract: The present disclosure provides a shielding apparatus for a lower end of an injection needle and an injection device, and relates to the technical field of injection instruments. By using the shielding apparatus for a lower end of an injection needle in the present disclosure, in the process of mounting a needle holder on an insulin pen, and when the injection needle is completely removed from the insulin pen, the limit block also moves downwardly to abut against a bottom wall of the moving groove, and the shielding cylinder completely covers the lower end of the injection needle, so as to avoid a situation that a user accidentally touches the lower end of an injection needle to be injured, thereby avoiding the safety risk when the lower end of the injection needle is removed.

Abstract: 1. A drug delivery device for delivering a plurality of fixed doses of a medicament, wherein the drug delivery device comprises a needle magazine with a plurality of needle assemblies, a needle positioning mechanism, a drive mechanism for delivering a fixed dose of the plurality of fixed doses, in response to activation, an activation mechanism for activating the drive mechanism comprising a movable shield (110, 310), wherein the shield (110, 310) is adapted to activate the drive mechanism, in response moving the shield to the proximal position. The drug delivery device further comprises a drop lock mechanism comprising a non-blocking state and a blocking state.

Abstract: The present disclosure relates to a device to provide a discomfort-reducing sensations to an area in preparation for injection or other needle puncture. The system includes a vibration source, as well as an electrical stimulation source. These two operate in combination to cause a numbing sensation to the patient, at which point a needle can puncture the skin without causing pain, discomfort, flinching, and mental distress.

Abstract: Fluid management systems are disclosed that include software-controlled, electro-mechanical devices used in combination with single-use or multi-use tubing sets. Functions of the fluid management systems can include fluid pressurization, fluid warming, fluid deficit monitoring (including flow-based and weight-based), suction, fluid collection, and fluid evacuation (including indirect-to-drain and direct-to-drain options). The systems can be configured based on the surgical environment (e.g., operating room or physician office) as well as other user needs and/or preferences.

Abstract: A method for treating or repairing a damaged spinal disc of a patient may include inserting, using medical imaging, a shaft with a lumen extending from an exterior of a patient to the damaged spinal disc, dispensing copper particles, using the lumen, to the damaged spinal disc, and removing the hollow shaft from the patient. A system may include a syringe and copper particles in the syringe. A kit may include copper particles, and at least one of a guidewire, one or more dilators, a tubular retractor, a disposable endoscope, a disposable laser fiber; an endoscopic ronjeurs, indigo carmine dye, or a fluid adaptor.

Abstract: An aerosol delivery device is provided that includes at least one housing, a nozzle, a piezoelectric or piezomagnetic material, a control component, and a transport element. The at least one housing may enclose a reservoir configured to retain an aerosol precursor composition. The nozzle may be coupled to the housing to discharge aerosol precursor composition from the reservoir. The control component may include a microprocessor coupled to and configured to drive the piezoelectric or piezomagnetic material to vibrate and cause a discharge of components of the aerosol precursor composition and thereby produce an aerosol for inhalation by a user. And the transport element may be configured to control an amount of aerosol precursor composition delivered from the reservoir.

Abstract: An aerosol-generating system for heating a liquid aerosol-forming substrate is provided, the aerosol-generating system including: an aerosol-forming chamber; and a leakage preventer configured to prevent or reduce leakage of liquid aerosol condensate from the aerosol-generating system.

Abstract: The method includes defining a chamber withing a first housing, the chamber including a first-shaped cavity and a second-shaped cavity configured to receive a first-type consumable and a second-type consumable, respectively.

Abstract: A manifold assembly for a surgical gas delivery system is disclosed, which includes a manifold body including an inlet port for receiving gas from an outlet side of a compressor and an outlet port for recirculating gas to an inlet side of the compressor, a bypass valve communicating with the inlet port and the outlet port of the manifold body, an air ventilation valve for dynamically controlling the ingress of air from atmosphere, a smoke evacuation valve for dynamically controlling the egress of gas from the manifold assembly when the gas delivery system is operating in a smoke evacuation mode, and a gas fill for dynamically controlling the receipt of gas from a source of surgical gas.

Abstract: A mist inhaler device (200) for generating a mist comprising a therapeutic for inhalation by a user. The device comprises a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

Abstract: Devices, and methods for generating variable inhalable products (e.g., variable density, phase, and size products) are provided. Methods for treating or preventing a disorder in a subject using variable products generated by the devices are also provided herein. Additionally, inhalers and breathing systems comprising the devices are provided.

Abstract: A breath actuated metered dose inhaler including a housing, a canister and a trigger mechanism. The trigger mechanism is activated by the inhalation of air which comprises of a diaphragm. The central rigid disk of the diaphragm is provided with the interlocking means to firmly secure and bound the peripheral flexible polymer ring with the central rigid disc. The mechanical interlock between a central rigid disk and a peripheral flexible polymer ring on the diaphragm prevent peripheral flexible polymer ring from being peeled off from the central rigid disc while the vacuum is being retained prior to inhalation.

Abstract: An electronic cigarette includes a circumferential light guide that distributes light transmitted by a light source, and controller circuitry that variably illuminates the circumferential light guide of the electronic cigarette based on a user's draw strength.

Abstract: A mouthpiece for an apparatus for generating an inhalable medium is disclosed. The mouthpiece defines an aperture extending from a first opening at a first end of the mouthpiece to a second opening at an opposing end of the mouthpiece. The mouthpiece is arranged to receive in the aperture through the first opening a flavor element for imparting a flavor to a flow of at least one of a vapor and an aerosol that passes through the mouthpiece in use. The aperture has a first radial dimension towards the first opening, and a second radial dimension towards the second opening, wherein the second radial dimension is smaller than the first radial dimension.

Abstract: A system of treating atelectasis is provided that includes a tracheal tube positioned within an airway of a ventilated patient and an acoustic sensor coupled to the tracheal tube. The system also includes a monitor communicatively coupled to the acoustic sensor. The monitor includes a processor configured to receive a baseline signal from the acoustic sensor. The processor is configured to provide control instructions to adjust a pressure of a gas mixture delivered to the airway through the tracheal tube. The processor is also configured to receive an updated signal from the acoustic sensor after the adjustment and identify a change in airway openness of lungs of the ventilated patient caused by the adjustment of the pressure. Further, identifying the change is based on the baseline signal and the updated signal.

Abstract: A cradle style cushion includes a central sealing body portion including a front wall, a rear wall, a top wall and a bottom wall. The top wall includes a central sealing surface, a first stabilizing surface and a second stabilizing surface, the first and second stabilizing surfaces each extending upwardly and outwardly with respect to the central sealing surface and a top edge of the front wall and being structured to wrap around and engage an outside of the nostrils when the patient interface device is donned by the patient, wherein the first stabilizing surface includes a first front side edge portion and the second stabilizing surface includes a second front side edge portion, and wherein the top edge of the front wall, the first front side edge portion and the second front side edge portion together define a front opening of the central sealing body portion.

Abstract: A respiratory mask can have a frame supporting a sealing arrangement. Various features of the frame and sealing arrangement can improve comfort and reduce the occurrence of pressure sores. The frame can include cheek supports that have a large surface area configured to spread loads over a greater area of the patient's face and therefore reduce the forces applied to the face and the occurrence of point loads. The seal can have a main body that includes a spring with a silicone skin, wherein the spring applies a substantially constant force to the face and/or nares of the patient.

Abstract: An interface includes a mask. The mask includes a frame and a seal supported by the frame. Headgear is connected to the mask. The interface includes at least one of (i) an adjustment mechanism that can be set to a use length for a loop defined by the mask and the headgear; and (2) a break-fit assembly that can selectively lengthen the loop defined by the mask and the headgear and return to the use length.

Abstract: This disclosure relates to a control system for a portable oxygen concentrator (POC). Specifically, this disclosure relates to a method and a system configured for use with an oxygen delivery system that includes nasal fitting which does not include nostril prongs. Because the nasal fitting does not include nostril prongs, user comfort is dramatically increased relative to prior designs. That said, because the fitting is free of nostril prongs, changes in pressure associated with the user's breathing register less than in oxygen delivery systems with traditional fittings (i.e., those that include nostril prongs). As such, the method and system of this disclosure is configured to associate relatively small changes in pressure with a breathing cycle of a user, thereby permitting effective and efficient POC operation.

Abstract: Devices (100) for calming or mixing gases are provided. The devices (100) enable calming and/or mixing with an integrated mixing geometry, integration of sensors and actuators, and optimized conduction as well as provision of the mixed gases. The devises include one or more gas inlets, a gas outlet and a mixing system, including the integrated mixing geometry that is manufactured integrally and gas-tight in a manufacturing or joining process which is based on a formation of a form-fitting and/or force-fitting as well as gas-tight connection of plastic materials and/or metallic materials based on a printing technology or 3D printing technology.

Abstract: An HME device has a housing (10) containing an HME element (25). The device has a first gas-flow passage through the device via the HME element (25) and a second gas-flow passage that by-passes the HME element. Flow is switched between the first or second flow passage by a pivoted shutter (30) that can be displaced by a rotatable knob (32).

Abstract: A water tank mounting structure and a ventilation treatment apparatus is provided. The water tank mounting structure comprises a cavity for containing a water tank, a back wall for defining the cavity, at least one side wall for defining the cavity, and a guiding assembly for guiding the water tank to assemble to the cavity. The back wall is provided with at least one opening for transmitting a respiratory gas between a main unit of the ventilation treatment apparatus and the water tank. The guiding assembly is set such that when the water tank is assembled into the cavity, at least one gas port of the water tank is aligned to the at least one opening of the back wall. The guiding assembly includes at least one first guiding component provided on the back wall and a second guiding component provided on the at least one side wall.

Abstract: The present invention relates to a wearable smartwatch system for detecting negative emotions of a wearer of the smartwatch of the system. The system includes an earbud coupled to the smartwatch using a Bluetooth connection. More specifically, the smartwatch includes a plurality of electrodes for measuring HRV and electrodermal activity of the wearer. A processor of the smartwatch processes the data measured by the electrodes to determine emotional state of the wearer. A pre-recorded audio is automatically played out through the earbud to help calm down the wearer upon determination of the negative emotional state. In some embodiments, an alert signal is sent to a parent, teacher, or other caregiver to obtain assistance for a wearer to cope with negative emotions and feelings.

Abstract: Urinary catheters (100) that have drainage holes (112) that impart a desired flexibility to the proximal insertion end portion of the catheter.

Abstract: Aspects of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such aspects can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some aspects can include a sheath with a tubular inner liner wound in a spiral configuration such that a plurality of protrusions is disposed in an overlapping portion of the sheath. The disclosed sheath is configured to expand from a predetermined rest diameter dr to an expanded diameter de during application of a radial outward force by passage of a medical device through the sheath.

Abstract: A system suitable for delivering a therapeutic agent to a target site includes: a container for holding a therapeutic agent; a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the container; a catheter in selective fluid communication with the container and configured for delivery of the therapeutic agent or delivery of the pressurized fluid without the therapeutic agent to a target site; a first valve connected between the pressure source and the container; and a housing configured to securely retain the container and rotationally support a button, wherein the button is configured to selectively actuate the first valve to deliver the therapeutic agent or deliver the pressurized fluid without the therapeutic agent.

Abstract: A catheter includes a shaft portion defining a non-circular transverse cross-section. The shaft portion includes an exterior sidewall and an interior sidewall defining two or more asymmetrical working channels.