Patents Issued in June 25, 2024
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Patent number: 12017953Abstract: An alkali-free glass has a strain point of 650° C. or more, an average coefficient of thermal expansion at 50 to 350° C. of from 30×10?7 to 45×10?7/° C., and a temperature T2 at which a glass viscosity reaches 102 dPa·s of from 1,500 to 1,800° C. The alkali-free glass contains, as represented by mol % based on oxides, SiO2: from 62 to 70%, Al2O3: from 9 to 16% B2O3: from 0 to 12%, MgO: from 3 to 10%, CaO: from 4 to 12%, SrO: from 0 to 6%, and Fe2O3: from 0.001 to 0.04%, provided that MgO+CaO+SrO+BaO is from 12 to 25%. The alkali-free glass has a ?-OH value of from 0.35 to 0.85/mm.Type: GrantFiled: October 14, 2020Date of Patent: June 25, 2024Assignee: AGC Inc.Inventors: Hirofumi Tokunaga, Kazutaka Ono, Motoyuki Hirose
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Patent number: 12017954Abstract: An electromagnetic interference (EMI) resistant cementitious ink comprising a hydraulic cement, calcium carbonate, silica sand, taconite material, and a conductive material. A ratio of the silica sand to the taconite material is 1:1. In some embodiments, the taconite material includes taconite powder and fine taconite aggregate having a ratio of 1:1. In some embodiments, the conductive material includes carbon-based nanoparticles in solution. In further embodiments, the EMI-resistant cementitious ink has a shielding effectiveness in accordance with ASTM D4935-18 of at least 4.0 dB.Type: GrantFiled: July 7, 2021Date of Patent: June 25, 2024Assignee: ICON Technology, Inc.Inventors: Kunal Kupwade-Patil, Theodore Richard Cera, J. Cole Sargent, Aida Margarita Ley Hernandez, Daniel Galvez Moreno, Alexander Le Roux
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Patent number: 12017955Abstract: A cementitious composition comprises cement and crystalline cellulose or nanocrystalline cellulose formed from a cellulosic material by a redox reaction.Type: GrantFiled: September 9, 2019Date of Patent: June 25, 2024Inventors: Sean McAlpine, Jory Nakoneshny, Blaine Kunkel
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Patent number: 12017956Abstract: Disclosed is a method for preparing bittern-carbonization synergistic reinforced recycled aggregate, including the following steps: spray pretreatment: performing alternate spraying on recycled aggregate with bittern and lime milk at intervals for many times at 4-70° C. and a pressure of 0.05-0.6 MPa; carbonization reinforcement: introducing waste gas containing carbon dioxide for a retention time of 4-8 h after the recycled aggregate is allowed to stand for 2-4 h; and rinsing and air drying: removing soluble impurities on a surface of the recycled aggregate by rinsing in water, and performing air-drying on the recycled aggregate to obtain bittern-carbonization synergistic reinforced recycled aggregate. According to the present disclosure, the effective reinforcement of recycled aggregate at normal temperature and pressure in a short time is realized, and the method is simple in process and is convenient in operation.Type: GrantFiled: February 23, 2024Date of Patent: June 25, 2024Assignee: Yangzhou UniversityInventors: Changjiang Kou, Jiyang Sun, Zhiwei Sun, Yu Lu, Rongxue Fan, Peng Xiao, Aihong Kang, Zhengguang Wu
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Patent number: 12017957Abstract: A method includes adding (i) a comb polymer and (ii) a plasticizer to a mineral binder composition comprising swellable clays. The comb polymer includes: at least one poly(alkylene oxide) side chain-bearing monomer unit without ionic groups, optionally at least one cationic monomer unit, optionally at least one anionic monomer unit, and optionally, at least one non-ionic monomer unit, wherein a molar ratio of the cationic monomer units to the side chain-bearing monomer units is equal to or less than 10, a molar ratio of the anionic monomer units to the side chain-bearing monomer units is less than 1, and a molar ratio of the non-ionic monomer units to the side chain-bearing monomer units is less than 5.Type: GrantFiled: November 18, 2022Date of Patent: June 25, 2024Assignee: SIKA TECHNOLOGY AGInventors: Ulf Velten, Jürg Weidmann, Lukas Frunz, Patrick Juilland
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Patent number: 12017958Abstract: Methods and compositions for the installation of scientifically engineered and constructed unpaved runways are disclosed herein. The compositions are heterogeneous mixtures produced by blending aliphatic or cyclic organic compounds with binders that chemically react with gravel, aggregate, and soil particles to create permanent bonds, resulting in a strengthened and stabilized surface. When blended into the aggregate of a runway surface, the organic compounds act as a carrier fluid, distributing the binder system evenly so particles of all sizes are thoroughly and uniformly coated with the composition. Once the composition is distributed, an adhesion promoting compound reacts with constituents in the aggregate to increase the formation and strength of chemical bonds between particles.Type: GrantFiled: March 27, 2023Date of Patent: June 25, 2024Inventors: Robert W. Vitale, Matthew Lyons, Matthew Mefford, Maurice Fenelon, Gina Greenlee
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Patent number: 12017959Abstract: Disclosed is an amphiphilic multifunctional hybrid nanoparticle. The nanoparticle of the present invention has a detachable hydrophilic organic polymer with both a water-soluble long chain and a hydrophobic long hydrocarbon functional group attached to the surface, wherein the body of the nanoparticle is a silica or an organofunctional group substituted silica or an organofunctional group substituted silicon-oxygen bond network, and the nanoparticle contains a free organosiloxane with hydrophobic long hydrocarbon functional groups and a fatty acid or fatty acid ester or aluminum complex of fatty acid with hydrophobic long hydrocarbon functional groups.Type: GrantFiled: March 8, 2019Date of Patent: June 25, 2024Assignees: SOBUTE NEW MATERIALS CO., LTD., NANJING BOTE NEW MATERIALS CO., LTD., BOTE NEW MATERIALS TAIZHOU JIANGYAN CO., LTD.Inventors: Xin Shu, Qianping Ran, Yong Yang, Xiumei Wang, Jinzhi Liu, Jiangang Zhang, Hongxia Zhao
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Patent number: 12017960Abstract: A preparation method of heat-resistant adhesive of silicon-boron-carbon-zirconium modified aluminum-zirconium phosphate for zirconium oxide ceramics is provided. The high-temperature adhesive can generate various high-temperature resistant phases such as zirconia, aluminum phosphate, zirconium phosphate and aluminum borate in situ of the high-temperature adhesive at high temperatures. As the processing temperature increases, the content of zirconia in the high-temperature adhesive continuously increases, and the composition tends to form a stable composite phase mainly composed of aluminum phosphate and zirconia, which makes the composition of the high-temperature adhesive closer to that of zirconia ceramics.Type: GrantFiled: February 2, 2024Date of Patent: June 25, 2024Assignee: Civil Aviation University of ChinaInventors: Qingsong Zhang, Mingchao Wang, Haijun Zhang
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Patent number: 12017961Abstract: Provided in certain embodiments are high performance graphene fibers and yarns, including components and precursors thereof, and composites comprising the same. Also provided herein are methods of manufacturing such fibers, yarns, composites, and components/precursors thereof.Type: GrantFiled: May 16, 2018Date of Patent: June 25, 2024Assignee: Cornell UniversityInventors: Yong Lak Joo, Ling Fei, Seung Wan Kim
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Patent number: 12017962Abstract: Provided is a method including obtaining ceramic matrix composite (CMC) with a first matrix portion including a silicon carbide and silicon phase dispersed therewithin, disposing a coating thereupon to form a sealed part, and forming thereupon another segment comprising a CMC, which may be another matrix portion including a silicon carbide and a silicon phase dispersed within therewithin. Also provided is a gas turbine component with a CMC segment including a matrix portion including a silicon carbide and a silicon phase dispersed therewithin, a sealing layer including silicon carbide enclosing the first segment, and a second segment on the sealing layer, wherein the second segment includes a melt-infiltrated CMC having a matrix portion including a silicon carbide and a silicon phase dispersed therewithin.Type: GrantFiled: March 3, 2020Date of Patent: June 25, 2024Assignee: General Electric CompanyInventors: Daniel Gene Dunn, Gregory Scot Corman, Jared Hogg Weaver
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Patent number: 12017963Abstract: A low density annular grout composition for filling voids. The composition may consist of cementitious fly ash, water, set retarder and cellular foam. The composition may have a compressive strength of between 100 and 600 psi at seven days and less than 1500 psi at 28 days. The composition may have a density between 20 and 75 pcf. Also disclosed is a method of filling a void with a low density annular grout composition. The method can include determining the time necessary to fill the void, adding water and set retarder to a cementitious fly ash to make a wet mixture, adding air to the wet mixture, and adding the composition to the void.Type: GrantFiled: December 22, 2020Date of Patent: June 25, 2024Assignee: EAGLE STRONG INVESTMENTS, LLCInventors: Stanley R. Peters, George Clarence Geal, III
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Patent number: 12017964Abstract: A plant growth enhancer including a source of carbon dioxide, a source of carbohydrate, and source of acid in an amount to provide increased retention of carbon dioxide in the soil.Type: GrantFiled: March 9, 2023Date of Patent: June 25, 2024Assignee: INNOVATIONS FOR WORLD NUTRITION, LLCInventors: Arthur R. Shirley, Jr., Melissa C. Hayes
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Patent number: 12017965Abstract: A chelated zinc adjuvant composition includes water, an effective amount of a micronutrient consisting of zinc chelated with an organic acid and an organic amine, a mono-, di- or polysaccharide and an alkyl polysaccharide. The adjuvant has a pH of up to 6.5. When admixed with a pesticide capable of precipitating with the zinc, due to the zinc being chelated, the zinc is prevented from precipitating with the pesticide and is available for uptake. When the adjuvant composition is applied in seed, soil, foliage or fruit applications, zinc uptake is improved.Type: GrantFiled: August 25, 2020Date of Patent: June 25, 2024Assignee: WinField Solutions, LLCInventors: James Dwight Scott, Danny Brown
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Patent number: 12017966Abstract: A product, system and method for an improved plant fertilizer made from harvested skimmate from a reservoir filed with a reduced sodium, artificial ocean water solution and live fish that produce fish excrement (reclaimed as skimmate). The skimmate contains a reduced concentration of sodium as a result of being harvested from a reduced sodium aquatic solution. The harvested skimmate is mixed with one or more additives to produce an improved fertilizer that may be certified as organic.Type: GrantFiled: December 26, 2019Date of Patent: June 25, 2024Assignee: FOOP ORGANIC BIOSCIENCES, INC.Inventors: Laurence J. Footer, Jonathan V. Goslin
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Patent number: 12017967Abstract: A method of increasing organic carbon in a soil is disclosed. The method includes inoculating the soil and/or a plant growing in the soil with one or more fungal strains from at least one genus selected from the group consisting of Acrocalymma, Clonostachys, Leptodontidium, Periconia, Phaeosphaeria, Thozetella, Trichoderma, and a combination thereof, wherein the one or more fungal strains are in an amount effective to increase organic carbon in the soil compared to a non-inoculated control soil. Also disclosed is a method of enhancing plant growth, comprising: applying to a plant, a plant part, or the locus surrounding the plant with one or more fungal strains from at least one genus selected from the group consisting of Acrocalymma, Clonostachys, Leptodontidium, Periconia, Phaeosphaeria, Thozetella, Trichoderma, and a combination thereof in an amount effective to enhance the growth of the plant as compared to an untreated control plant.Type: GrantFiled: January 6, 2024Date of Patent: June 25, 2024Assignee: Loam Bio Pty LtdInventors: Ray Riley, Andres Reyes, Abed Chaudhury, Suresh Subashchandrabose, Ahsanul Haque, Neeraj Purushotham, Raghvendra Sharma, Tegan Nock, Gyongyver Korosi, Brooke Bruning, Grace Scott, Venkatachalam Lakshmanan
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Patent number: 12017968Abstract: The present invention relates to increasing longevity of the nitrogen content of soil through improved liquid delivery formulations of nitrification inhibitors. The liquid formulation can also be comprised of nitrification inhibitors and optionally urease inhibitors that are blended solutions of each. The nitrification inhibitors are present in a mixture that comprises both a protic and an aprotic solvent system. The novel formulations are designed to be applied to fertilizers, especially urea and manure based fertilizers. The delivery formulations provide an environmentally sound and inherently safe solvating system that improves the storage stability of the urease inhibitors by utilizing liquid organic non-water containing solvents, maintains the nitrification inhibitors in solution to storage temperatures of at least 10° C., and provides improved application to fertilizer of nitrification inhibitors.Type: GrantFiled: March 28, 2022Date of Patent: June 25, 2024Assignee: SOILGENIC TECHNOLOGIES, LLCInventors: Gary David McKnight, Randall Linwood Rayborn, Wei Xu, Raymond Patrick Perkins, Zehui Yang, David Parker, Andrew Semple
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Patent number: 12017969Abstract: The present invention relates to increasing longevity of the nitrogen content of soil through improved liquid delivery formulations of nitrification inhibitors. The liquid formulation can also be comprised of nitrification inhibitors and optionally urease inhibitors that are blended solutions of each. The nitrification inhibitors are present in a mixture that comprises both a protic and an aprotic solvent system. The novel formulations are designed to be applied to fertilizers, especially urea and manure based fertilizers. The delivery formulations provide an environmentally sound and inherently safe solvating system that improves the storage stability of the urease inhibitors by utilizing liquid organic non-water containing solvents, maintains the nitrification inhibitors in solution to storage temperatures of at least 10° C., and provides improved application to fertilizer of nitrification inhibitors.Type: GrantFiled: August 27, 2022Date of Patent: June 25, 2024Assignee: SOILGENIC TECHNOLOGIES, LLCInventors: Gary David McKnight, Randall Linwood Rayborn, Wei Xu, Raymond Patrick Perkins, Zehui Yang, David Parker, Andrew Semple
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Patent number: 12017970Abstract: Processes for converting a hydrocarbon reactant into an alcohol compound and/or a carbonyl compound are disclosed in which the hydrocarbon reactant and a supported transition metal catalyst—containing molybdenum, tungsten, or vanadium—are irradiated with a light beam at a wavelength in the UV-visible spectrum, optionally in an oxidizing atmosphere, to form a reduced transition metal catalyst, followed by hydrolyzing the reduced transition metal catalyst to form a reaction product containing the alcohol compound and/or the carbonyl compound.Type: GrantFiled: September 1, 2023Date of Patent: June 25, 2024Assignee: Chevron Phillips Chemical Company LPInventors: Masud M. Monwar, Jared Barr, Carlos A. Cruz, Kathy S. Clear, Max P. McDaniel, William C. Ellis
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Patent number: 12017971Abstract: A C10 hydrocarbon composition of greater than 55 wt. % C10 mono-olefins contains 1-decene, 2-butyl-1-hexene, 3-propyl-1-heptene, 4-ethyl-1-octene, 4-penten-1-yl-cyclopentane, and 5-methyl-1-nonene. A C12 hydrocarbon composition of greater than 60 wt. % C12 mono-olefins contains 1-dodecene, 6-hepten-1-yl-cyclopentane, heptylcyclopentane and n-dodecane. A C14 hydrocarbon composition of greater than 60 wt. % C14 mono-olefins contains 1-tetradecene, 8-nonen-1-yl-cyclopentane, n-tetradecane, and nonylcyclopentane.Type: GrantFiled: June 26, 2023Date of Patent: June 25, 2024Assignee: Chevron Phillips Chemical Company LPInventor: Orson L Sydora
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Patent number: 12017972Abstract: A family of low-molecular-weight, main-chain thermotropic liquid-crystalline polyimides (TLC-PI) that are crosslinkable is disclosed. These all-aromatic TLC-PI are derived from (i) wholly aromatic and flexible diamine monomers, in which the linkage between the two aniline-ends contains a relatively high heat-tolerant but flexible chain constituted by two or more units of 1,4-phenoxy or 1,3-phenoxy or in combinations of both. Processes of making and using such all-aromatic TLC-PI is also provided.Type: GrantFiled: April 12, 2023Date of Patent: June 25, 2024Assignee: The Government of the United States of America as Represented by the Secretary of the Air ForceInventors: Loon-Seng Tan, Zhenning Yu
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Patent number: 12017973Abstract: Described herein are alkoxylated compounds of general formula (I) and their use as adjuvant in the treatment of soil and plants. Also described are a composition including at least one biocide and at least one compound of general formula (I), as well as a method for improving the growth and health of plants by treating the crops with the composition including the compounds of general formula (I).Type: GrantFiled: June 11, 2019Date of Patent: June 25, 2024Assignee: BASF SEInventors: Rodney F. Kilma, Dean A. Oester, Timothy H. Anderson, Mahmud Mustaqim Hussain
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Patent number: 12017974Abstract: The present specification relates to an adamantanecarboxylic acid benzyl amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, and a skin whitening composition comprising the same as an active ingredient. Specifically, the compound, according to the present specification, is a compound having a novel structure having adamantanecarboxylic acid bound to an amine compound, and exhibits a skin whitening effect by inhibiting the production of melanin, and thus may be used in various ways as a pharmaceutical composition, a cosmetic composition or a skin preparation for external use.Type: GrantFiled: January 3, 2020Date of Patent: June 25, 2024Assignee: AMOREPACIFIC CORPORATIONInventors: Yunghyup Joo, Jaeyoung Ko, Jaewon You, Yong Jin Kim, Tae Ryong Lee
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Patent number: 12017975Abstract: Provided herein are Myc-Max inhibitory compounds having the structure of Formula (I) and compositions thereof for use in the treatment of cancer. In particular, the Myc-Max inhibitory compounds may be useful for the treatment of cancers selected from one or more of: prostate cancer, breast cancer, colon cancer, cervical cancer, small-cell lung carcinomas, neuroblastomas, osteosarcomas, glioblastomas, melanoma and myeloid leukaemia.Type: GrantFiled: October 14, 2022Date of Patent: June 25, 2024Assignee: THE UNIVERSITY OF BRITISH COLUMBIAInventors: Artem Tcherkassov, Paul S. Rennie, Fuqiang Ban, Eric J. J. Leblanc, Lavinia A. Carabet, Nada Lallous, Kriti Singh, Helene Morin, Anh-Tien Ton
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Patent number: 12017976Abstract: Synthesis of a compound 1-(4-carbonoimidoylphenoxy)-3-{4-[(E)-(phenylimino)methyl]phenoxy}propan-2-ol and its use as an insecticidal agent.Type: GrantFiled: January 4, 2024Date of Patent: June 25, 2024Assignee: KING FAISAL UNIVERSITYInventors: Mai Mostafa Khalaf Ali, Hany Mohamed Abd El-Lateef Ahmed, Mohamed Gouda, Antar Ahmed Abdelhamid Ahmed, Mohamed A. Gad
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Patent number: 12017977Abstract: A method for producing a carbodiimide compound, comprising a carbodiimide production step of reacting an aliphatic tertiary isocyanate compound (A) in the presence of an organic alkali metal compound (B) having Lewis basicity.Type: GrantFiled: December 6, 2022Date of Patent: June 25, 2024Assignee: NISSHINBO CHEMICAL INC.Inventors: Nobuyuki Matsumoto, Kenichi Yanagisawa
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Patent number: 12017978Abstract: A method for preparing isopropyl alcohol including: feeding a feed stream containing a propylene monomer and water to a reaction unit, where the propylene monomer and the water react to form a reaction product containing isopropyl alcohol, the propylene monomer, and the water; feeding each of a first discharge stream and a second discharge stream discharged from the reaction unit to a stripper, where the first discharge stream contains a vapor-phase reaction product, which is condensed through a first heat exchanger and fed to the stripper in a liquid-phase, and wherein the second discharge stream contains a liquid-phase reaction product; and separating a top discharge stream and a bottom discharge stream from the stripper, wherein the top discharge stream contains the propylene monomer and the bottom discharge stream contains the water and the isopropyl alcohol.Type: GrantFiled: November 25, 2020Date of Patent: June 25, 2024Assignee: LG Chem, Ltd.Inventors: Sa Eun Park, Tae Woo Kim, Sung Kyu Lee
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Patent number: 12017979Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.Type: GrantFiled: March 23, 2023Date of Patent: June 25, 2024Assignee: ENA Respiratory Pty LtdInventors: Ian Holmes, Weiguang Zeng, David Jackson, Christophe Demaison, Grant McLachlan
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Patent number: 12017980Abstract: Provided are a monofunctional phenolic compound used for producing an active ester resin capable of forming a cured product having excellent dielectric properties and excellent heat resistance, an active ester resin and a method for producing the active ester resin, and a thermosetting resin composition and a cured product of the thermosetting resin composition. Specifically, provided are a monofunctional phenolic compound including one or more vinylbenzyl groups and an active ester resin including a vinylbenzyl structure attached to a terminal group of the molecular chain and derived from the monofunctional phenolic compound. The vinylbenzyl structure preferably includes a vinylbenzyl-modified aryloxycarbonyl group.Type: GrantFiled: September 12, 2019Date of Patent: June 25, 2024Assignee: DIC CorporationInventors: Masaki Hazama, Koji Hayashi
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Patent number: 12017981Abstract: Disclosed is a method for preparing acetaldehyde from acetylene under the catalysis of a ZAPO molecular sieve. The method comprises the steps of pre-heating an acetylene raw material gas and water, subjecting same to continuous hydration in a fluidized bed under the catalysis of the ZAPO molecular sieve to prepare acetaldehyde, and then subjecting same to separation, absorption and rectification to obtain an acetaldehyde product, wherein the catalyst can be continuously regenerated for use. The process of the present application is simple, stable and efficient, solves the problem of the dependence nature of the production of acetaldehyde by means of acetylene hydration on a mercury catalyst, avoids the harm caused by mercury to the human body and the environment, and has higher production and use values.Type: GrantFiled: April 28, 2021Date of Patent: June 25, 2024Assignee: BOZUN INVESTMENT GROUP LIMITEDInventors: Yibo Jiang, Yufan Ying, Zheng Li
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Patent number: 12017982Abstract: A process for the hydroformylation of olefins to aldehydes is disclosed. The process comprises: hydroformylating one or more olefins with hydrogen and carbon monoxide in the presence of a ligand-rhodium catalyst in a reaction zone; recovering a reactor effluent from the reaction zone, the reactor effluent comprising product aldehyde and the ligand-rhodium catalyst; passing the reactor effluent and a strip gas to a vaporiser, wherein the strip gas comprises carbon monoxide and is formed from a recycle strip gas stream and a make-up strip gas stream, wherein the product aldehyde is vaporised into the strip gas in the vaporiser resulting in a vapour mixture, comprising the strip gas and the product aldehyde, and a liquid mixture, comprising the ligand-rhodium catalyst; recovering the liquid mixture and recycling the ligand-rhodium catalyst to the reaction zone; recovering the vapour mixture and separating the product aldehyde from the vapour mixture.Type: GrantFiled: May 29, 2020Date of Patent: June 25, 2024Assignee: Johnson Matthey Davy Technologies LimitedInventors: Fraser Robert Archibald, Robert Arthur Jolly, Maria del Amo Lopez, David Keith Welch
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Patent number: 12017983Abstract: Systems and processes for dehydrogenating one or more alkanes using electrically heated dehydrogenation reactors. The source of electric energy or power can be a power grid, solar panel, windmill, hydropower, nuclear power, fuel cell, gas turbines, steam turbines, portable generator or the like. The systems and processes provided herein result in a simpler dehydrogenation process which is particularly beneficial at a small scale and at remote locations, including the well site.Type: GrantFiled: February 14, 2023Date of Patent: June 25, 2024Assignee: PURDUE RESEARCH FOUNDATIONInventors: Rakesh Agrawal, Zewei Chen, Peter Oladipupo
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Patent number: 12017984Abstract: A process for the treatment of sulfidic spent caustic, conditioned catalyst regeneration vent gas, C4 isomerization off gas, various and hydrocarbon containing liquid and gaseous streams in addition to toxic containing streams like cyanidic off gas and waste water in a propane/butane dehydrogenation complex is described. Various effluent streams are combined in appropriate collection vessels, including an off-gas knockout drum, a hydrocarbon buffer vessel, a spent caustic buffer vessel, an optional a waste water buffer vessel, and a fuel gas knockout drum. Streams from these vessels are sent to a thermal oxidation system.Type: GrantFiled: June 29, 2021Date of Patent: June 25, 2024Assignee: Honeywell International Inc.Inventors: Rui de Menezes, Jan De Ren, Tom Jackson, Madan K. M. Desai, Adam J. Kanyuh
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Patent number: 12017985Abstract: The present application pertains to processes producing oxides using a weak acid intermediate. In one embodiment a material comprising calcium carbonate is reacted with a solution comprising aqueous carboxylic acid to form a gas comprising carbon dioxide and a solution comprising aqueous calcium carboxylate. The solution comprising aqueous calcium carboxylate is reacted with sodium sulfate to form a solution comprising aqueous sodium carboxylate and a solid comprising calcium sulfate. The solution comprising aqueous sodium carboxylate is reacted with sulfur dioxide to form sodium sulfite and an aqueous carboxylic acid. The sodium sulfite is separated from said aqueous carboxylic acid and reacted to form a solid comprising calcium sulfite which is decomposed to form calcium oxide and sulfur dioxide.Type: GrantFiled: May 17, 2023Date of Patent: June 25, 2024Assignee: Innovator Energy, LLCInventor: Ethan Novek
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Patent number: 12017986Abstract: The present disclosure provides 15-oxo-EPA and 15-oxo-DGLA, compositions comprising 15-oxo-EPA and/or 15-oxo-DGLA, and methods of treating and/or preventing fibrosis, skin disorders, inflammation, kidney disease or renal dysfunction in a subject in need thereof by administering 15-oxo-EPA and/or 15-oxo-DGLA.Type: GrantFiled: November 16, 2021Date of Patent: June 25, 2024Assignee: DS Biopharma LimitedInventors: Mehar Manku, John Climax, David Coughlan
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Patent number: 12017987Abstract: A process can be used for preparing methyl methacrylate (MMA), by direct oxidative esterification of methacrolein. The MMA and polymers produced therefrom feature a very low yellowness index. A workup of the reactor output from the oxidative esterification of methacrolein allows for particularly discolouring by-products to be removed or degraded without significant MMA losses.Type: GrantFiled: November 9, 2022Date of Patent: June 25, 2024Assignee: RÖHM GMBHInventor: Steffen Krill
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Patent number: 12017988Abstract: A process discharges low boilers during production of dialkyl terephthalates or dialkyl phthalates having C8 to C11 alkyl radicals. The production is carried out using a C8 to C11 alcohol or a mixture of two or more C8 to C11 alcohols in one or more reactors. The low boilers formed during the reaction are separated off by an efficient process and thus cannot accumulate.Type: GrantFiled: May 25, 2022Date of Patent: June 25, 2024Assignee: Evonik Oxeno GmbH & Co. KGInventors: Dietmar Gubisch, Ralf Klaus Hinsken, Johannes Kraft, Thomas Schneider
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Patent number: 12017989Abstract: Disclosed herein are drug release polymer compounds and compositions comprising prostacyclin compounds of Formula (I), and methods of preparing the same.Type: GrantFiled: May 10, 2021Date of Patent: June 25, 2024Assignee: United Therapeutics CorporationInventor: Peter Laing
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Patent number: 12017990Abstract: The present disclosure provides systems and methods for producing aromatic compounds in high yield from a mixed aromatic feed stream. Also disclosed are systems and methods for producing aromatic compounds in high yield from oxygenated hydrocarbons such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like.Type: GrantFiled: October 13, 2022Date of Patent: June 25, 2024Assignee: VIRENT, INC.Inventors: Paul G. Blommel, Matthew Van Straten, Brice Dally
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Patent number: 12017991Abstract: The disclosure relates to compounds of formula (I): Among the substituents in a compound of formula (I), one of R4 and R5 is hydrogen and the other of R4 and R5 is —OSC2Rs6. The disclosure relates to compounds of formula (II): Among the substituents in a compound of formula (II), R6 is a halogen chosen from F, Cl, Br, and I. The disclosure relates to compositions comprising a compound of formulas (I) or (II) and an excipient. The disclosure relates to pharmaceutical compositions comprising a therapeutically effective amount of a compound of formulas (I) or (II). The disclosure relates to therapeutic uses of compounds of formulas (I) or (II).Type: GrantFiled: January 10, 2022Date of Patent: June 25, 2024Assignee: CAAMTECH, INC.Inventor: Andrew R Chadeayne
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Patent number: 12017992Abstract: Compounds and compositions that can modulate mitochondrial function in neuronal cells are provided herein, as are methods for using the compounds and compositions to treat or prevent conditions such as Alzheimer's disease. For example, compounds of Formula I, compositions containing the compounds, and methods for using the compounds and compositions are provided herein: wherein X is absent, CH2, or C(O); R1 is H, OH, CN, NO2, halo, C1-3 alkyl, C1-3 haloalkyl, C1-3 alkoxy, C1-3 haloalkoxy, C3-7 cycloalkyl, amino, C1-3 alkylamino, or di(C1-3 alkyl)amino; R2 is H or C1-6 alkyl; R3 is H, C1-6 alkyl, —C(O)(C1-3 alkyl), or —C(O)O(C1-3 alkyl); R4 is C3-10 cycloalkyl, C6-10 aryl, 5-10 membered heteroaryl, or 5-10 membered heterocycloalkyl, each optionally substituted by 1, 2, 3, or 4 independently selected R5 groups; and R5 is OH, CN, NO2, halo, C1-3 alkyl, C1-3 haloalkyl, C1-3 alkoxy, C1-3 haloalkoxy, C3-7 cycloalkyl, amino, C1-3 alkylamino, or di(C1-3 alkyl)amino.Type: GrantFiled: September 28, 2021Date of Patent: June 25, 2024Assignee: Mayo Foundation for Medical Education and ResearchInventors: Eugenia Trushina, Robert Greenhouse, Kevin Greenman, William Thomas
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Patent number: 12017993Abstract: Methods for preparing 5-fluoro-6-(bromo or chloro)picloram analogs, or derivatives thereof, from picloram acid, picloram ester, or the nitrile analog of picloram are provided. The methods include chemical process steps that: (1) introduce a phthaloyl group onto the 4-amino substituent of picloram acid, picloram ester, or the nitrile analog of picloram, (2) add 2 fluorine atoms at the 5,6-positions of the pyridine ring using halex fluorination chemistry, (3) remove the phthaloyl group, hydrolyze the ester or nitrile substituent, and add chlorine or bromine to the 6-position by treatment with an acid and water, and finally, (4) esterify the 5-fluoro-6-(bromo or chloro)picloram acid produced in step (3) to a 5-fluoro-6-(bromo or chloro)picloram ester.Type: GrantFiled: June 23, 2022Date of Patent: June 25, 2024Assignee: CORTEVA AGRISCIENCE LLCInventors: Jayachandran Devaraj, Nugzar Ghavtadze, Nicholas M. Irvine, Jeremy Kister, Melissa Lee, Ronald B. Leng, Rongrong [Mandy] Lin, Rong Ling, Noormohamed M. Niyaz, Abraham D. Schuitman, Aaron A. Shinkle, Siyu Tu, Gregory T. Whiteker, Chunming Zhang
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Patent number: 12017994Abstract: The present disclosure describes compounds and compositions that inhibit ?-glucuronidase activity, and methods for attenuating the side effects of one or more drugs and improving the efficacy of drugs by administration of selective ?-glucuronidase inhibitors.Type: GrantFiled: September 7, 2018Date of Patent: June 25, 2024Assignee: Symberix, Inc.Inventors: Francis X. Tavares, Bret D. Wallace, Ward Peterson
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Patent number: 12017995Abstract: The present invention relates to crystalline forms of the free base of the c-Met inhibitor, Compound 1. The invention also relates to crystalline forms of salts of Compound 1. The invention also relates to pharmaceutical compositions comprising the solid polymorphs of the free base and salts of Compound 1. The invention further relates to methods of treating a disease, disorder, or syndrome mediated at least in part by modulating in vivo activity of a protein kinase.Type: GrantFiled: December 12, 2019Date of Patent: June 25, 2024Assignee: Exelixis, Inc.Inventors: Frenel DeMorin, Khalid Shah, Sagar Shakya, Peter Wong, Courtney S. Johnson, Melanie Janelle Bevill, Stephan D. Parent
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Patent number: 12017996Abstract: The present disclosure is directed to formulations of novel quinolines and their pharmaceutically acceptable salts, which are useful for the treatment of protein kinases mediated diseases and conditions. The compounds of this disclosure have a general Formula I wherein R10 to R14 and X are defined herein.Type: GrantFiled: May 10, 2022Date of Patent: June 25, 2024Assignee: Jiangsu Medolution LtdInventor: Dawei Zhang
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Patent number: 12017997Abstract: Described herein are compounds, pharmaceutical compositions and methods of using these compounds and pharmaceutical compositions for treating and/or preventing conditions such as, for example, those caused by any viral family causing respiratory viral disease, including specifically coronaviruses and influenza viruses.Type: GrantFiled: October 24, 2022Date of Patent: June 25, 2024Assignee: Prosetta Biosciences, Inc.Inventors: Vishwanath R. Lingappa, Kumarapandian Paulvannan
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Patent number: 12017998Abstract: An 5-(2,4,5-tris(4-chlorophenyl)-1H-imidazol-1-yl)pentanoic acid compound, its synthesis, and its use as an antimicrobial agent.Type: GrantFiled: February 8, 2024Date of Patent: June 25, 2024Assignee: KING FAISAL UNIVERSITYInventors: Hany Mohamed Abd El-Lateef Ahmed, Mai Mostafa Khalaf Ali, Antar Ahmed Abdelhamid Ahmed, Amer A. Amer
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Patent number: 12017999Abstract: A 1-[4,5-bis(4-chlorophenyl)-1-hexyl-1H-imidazol-2-yl]-2-naphthol compound, its synthesis, and its use as an antimicrobial agent.Type: GrantFiled: November 7, 2023Date of Patent: June 25, 2024Assignee: KING FAISAL UNIVERSITYInventors: Hany Mohamed Abd El-Lateef Ahmed, Mai Mostafa Khalaf Ali, Antar Ahmed Abdelhamid Ahmed
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Patent number: 12018000Abstract: Here are described compounds for use as electrode additives or as salts in electrolyte compositions, and their methods of preparation. Also described are electrochemical cells comprising the compounds as electrode additives or as salts in electrolyte compositions.Type: GrantFiled: March 27, 2018Date of Patent: June 25, 2024Assignees: HYDRO-QUÉBEC, MURATA MANUFACTURING CO., LTD.Inventors: Charlotte Mallet, Sylviane Rochon, Antoine Lafleur-Lambert, Shinichi Uesaka, Karim Zaghib
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Patent number: 12018001Abstract: The present invention provides a class of pyrimidinedione cyclohexenyl compounds and methods of using these compounds as glucocorticoid receptor modulators.Type: GrantFiled: November 16, 2022Date of Patent: June 25, 2024Assignee: Corcept Therapeutics IncorporatedInventors: Hazel Hunt, Damien Francis Philippe Crepin, Joseph Thomas Hill-Cousins, Thomas Matthew Baker, Lorna Duffy
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Patent number: 12018002Abstract: Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.Type: GrantFiled: October 20, 2021Date of Patent: June 25, 2024Assignee: NEUPHARMA, INCInventors: Xiangping Qian, Yong-Liang Zhu