Patents Issued in July 11, 2024
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Publication number: 20240226532Abstract: A cable system for providing power to an implantable device implanted in a patient having a pedestal base mountable to a skull of a patient. An internal cable extends from the pedestal base and is electrically connectable to the implantable device. An external cable is connectable to the post of the pedestal base. A locking ring is releasably mountable to the post and is movable from a first configuration to a second configuration, wherein in the first configuration the locking ring locks to the post to secure the external cable to the pedestal base and in the second configuration the locking ring releases from the post to release the external cable from the pedestal base.Type: ApplicationFiled: March 9, 2022Publication date: July 11, 2024Applicant: Jarvik Heart Inc.Inventors: Robert Jarvik, Peter W.J. Hinchliffe
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Publication number: 20240226533Abstract: A blood pump comprises a pump casing having a blood flow inlet and a blood flow outlet connected by a passage, and an impeller rotatable about an axis of rotation. A surface of the impeller faces a surface of the pump casing spaced from said surface of the impeller by a clearance, the clearance being in fluid connection with the passage at a clearance transition point. At least one wash out channel extends through the impeller and is in fluid connection with the passage via a first opening and with the clearance via a second opening. The first opening of the wash out channel is arranged in an area of the impeller that is under a higher pressure than the clearance transition point so as to cause a blood flow from the first opening through the wash out channel and the clearance to the clearance transition point.Type: ApplicationFiled: August 14, 2023Publication date: July 11, 2024Applicant: Abiomed Europe GmbHInventors: Thorsten Siess, Walid Aboulhosn
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Publication number: 20240226534Abstract: A ventricular connecting assembly and a ventricular assist system. The ventricular connecting assembly comprises a clamping assembly and a locking assembly; the clamping assembly comprises an opening ring, a first connecting arm and a second connecting arm, and the opening ring has a first end and a second end; the first connecting arm) and the second connecting arm are respectively connected to the first end and the second end. The locking assembly comprises a connecting member and a locking member, the connecting member is connected to the second connecting arm, and the locking member is connected to the connecting member; the locking member is rotatably abutted against the first connecting arm, the locking member can adjust the inner diameter of the opening ring during rotation, and the locking member is snap-fitted with the second connecting arm to maintain the opening ring in a clamping state.Type: ApplicationFiled: July 26, 2022Publication date: July 11, 2024Inventors: Duanqing XIE, Shunzhou YU
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Publication number: 20240226535Abstract: An implantable shunt regulation device (1), with an electrically driven tube pinch valve (3) and means for electrically supplying, driving and wirelessly controlling the tube pinch valve (3), all components being arranged together in a single first closed housing (7) or separately in a first and second closed housing. The housing includes or forms a passage opening (71) for receiving a flexible shunt tube (102) or a body vessel. The tube pinch valve (3) is adjustable from outside the body (100) via a wireless connection. With the shunt regulation system (1) better adjustable and adaptable cardiac support systems (VAD) can, for example, be provided.Type: ApplicationFiled: May 9, 2022Publication date: July 11, 2024Inventors: Yalin Yildirim, Simon Pecha
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Publication number: 20240226536Abstract: The present invention relates to a device for regenerating nerve cells and suppressing immune diseases, and more particularly, to a device for regenerating nerve cells and suppressing immune diseases, which uses a contact lens containing a conductive material to increase the effect of microcurrent on nerve cell regeneration and immune response suppression. The device for regenerating nerve cells and suppressing immune diseases comprises: a contact lens comprising a body configured to be worn on a cornea, and a conductive material inserted into the body and serving to induce a microcurrent generated outside the body; a plurality of channels configured to come into close contact with skins around eyes and to generate a flow of microcurrent on upper part of the contact lens; and a signal supply unit configured to supply electrical signals to the plurality of channels.Type: ApplicationFiled: February 14, 2022Publication date: July 11, 2024Inventors: Tae Young CHUNG, Dong Hui LIM, Young Sik YOO, Do Hyoung KIM, Pyung Kyu KIM, Young Min PARK
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Publication number: 20240226537Abstract: A wound therapy system having a wound dressing for treating a wound includes a sensor that measures a pH level at a wound area. The sensor has a circuit that includes a first electrode and one or more second electrodes. The first electrode has a changeable conductivity that changes according to a hydrogen ion concentration level. The one or more second electrodes are configured with a fixed conductivity that does not change with the hydrogen ion concentration level. The first electrode is coated with a porous protective membrane formed from a sulfonated and/or carboxylated copolymer.Type: ApplicationFiled: October 15, 2020Publication date: July 11, 2024Inventors: Justin Alexander LONG, Konstantinos PETROPOULOS, Silvia GENERELLI, Christopher Brian LOCKE
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Publication number: 20240226538Abstract: A substantially planar neural electrode array includes a flexible base, a connector cable attached to the base, one or more flexible shafts protruding from the base. The shafts are arranged to protrude in the same plane from the same surface of the base to form a comb-like structure. Each of the one or more shafts includes one or more electrode contacts. The electrode contacts are electrically coupled to the connector cable. A first reinforcement layer extends over the base and a proximal part of the one or more shafts. The proximal part is adjacent to the base; a second resorbable reinforcement layer extends over a distal part of the one or more shafts. The distal part is distant from the base. There is an overlap between the first reinforcement layer and the second resorbable reinforcement layer.Type: ApplicationFiled: January 11, 2022Publication date: July 11, 2024Inventors: Frederik CEYSSENS, Samara FREY
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Publication number: 20240226539Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.Type: ApplicationFiled: March 22, 2024Publication date: July 11, 2024Inventors: John Michael Heasman, Peter Gibson, Stephen O'Leary, Luke Campbell
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Publication number: 20240226540Abstract: A novel ultra-thin neural implant (1) is provided that is based on a cellulose thin film (4) featuring an array (2) of electrodes (3). Due to the use of cellulose as the base material, the implant (1) can be safely handled during a micro-surgery, despite its high softness and conformability. Such an implant (1) may be useful in numerous applications ranging from electrical stimulation in neural prostheses, electro-stimulated regeneration of neural tissue to accurate recording of nerve signals. The robustness of the implant (1) results from a woven fabric (5) that is integrated in the cellulose carrier thin film (4). Several approaches for enhancing the tissue compatibility of the implant (1) are also provided.Type: ApplicationFiled: May 6, 2022Publication date: July 11, 2024Applicant: Universität Basel Vizerektorat ForschungInventors: Bekim OSMANI, Tino TÖPPER, Bert MÜLLER, Carina LUCHSINGER SALINAS, Raphael GUZMAN, Alois HOPF, Mahyar JOODAKI
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Publication number: 20240226541Abstract: A percutaneous lead is provided which includes a generally tubular, multi-duct, flexible lead body. The lead body supports a distal set of electrodes and a proximal set of contacts which are connected by conductors in the ducts. The lead body further houses an optical fiber with a side firing section. The side firing section is held adjacent an optical transmission window, integrally formed with the flexible lead body. A cylindrical ferrule is provided to position the fiber in the header of an IPG.Type: ApplicationFiled: February 5, 2024Publication date: July 11, 2024Applicant: Wavegate CorporationInventor: Erich W. Wolf, II
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Publication number: 20240226542Abstract: An electrical stimulation system includes at least one electrical stimulation lead, each of the at least one electrical stimulation lead including a plurality of stimulation electrodes; and a processor coupled to the lead and configured to perform actions, including: directing delivery of at least one electrical pulse through at least one of the stimulation electrodes of the at least one electrical stimulation lead to tissue of a patient; and directing discrete or intermittent measurement of an electrical characteristic of the tissue using at least one of the stimulation electrodes of the at least one electrical stimulation lead during, and after, delivery of the at least one electrical pulse to the tissue of the patient.Type: ApplicationFiled: March 20, 2024Publication date: July 11, 2024Inventor: Changfang Zhu
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Publication number: 20240226543Abstract: A self-anchoring helical wire structure electrode for energy conduction to or from a tissue target in a body, made of at least one wire rope consisting of biocompatible and conductive wire, and enclosing a hollow core within an inner diameter and having a longitudinal axis, an outer diameter and two ends, being flexible for self-bending in any direction up to 180 degrees on said longitudinal axis, and secured by being capable of self-forming a bunching anchor wider than the insertion channel when injected while its dispenser is substantially stationary.Type: ApplicationFiled: May 18, 2021Publication date: July 11, 2024Inventors: Stephan NIEUWOUDT, Manfred FRANKE, Shaher AHMED, Derrick LIU, Amelia HOWE, Emily SZABO, Jennifer PECK
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Publication number: 20240226544Abstract: A system for guiding implantation of an energy delivery component of a cardiac pacing device at a fixation location within a heart of a patient is provided. During a procedure to implant an energy pulse delivery component, the system receives a patient cardiogram collected during pacing of the energy pulse delivery component while the energy pulse delivery component is positioned at a current location within the heart. The system then determines based on the patient cardiogram the current location of the energy pulse delivery component. The system then outputs an indication of the current location to guide affixing of the energy pulse delivery component at the intended fixation location. This process is repeated until the energy pulse delivery component is at the fixation location. The system also evaluates the effectiveness of pacing at intermediate location to optimize the final location based upon simulated electro-mechanics of the system in near-real time.Type: ApplicationFiled: May 5, 2022Publication date: July 11, 2024Inventor: Robert Joseph Krummen
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Publication number: 20240226545Abstract: A microenvironment of a biological body is controlled, and more particularly, is measured, changed, and monitored with respect to temperature, pH level, moisture and other tissue parameters of a region of the body while, optionally, administering a therapeutic agent to that region.Type: ApplicationFiled: March 19, 2024Publication date: July 11, 2024Inventors: Peter M. Bonutti, Justin E. Beyers
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Publication number: 20240226546Abstract: The present disclosure provides electroporation catheters that are capable of forming a loop, generally a circular loop, an oval loop, or like in shape, located on the distal end portion of a catheter shaft within the vasculature of an individual. The electroporation catheters of the present disclosure may be delivered into the vasculature of the individual in a straight conformation and allow for the formation of the loop once positioned in the desired location. Some embodiments of the present disclosure include an electroporation catheter that includes a loop member pull wire in a spiral or helical configuration on an inside surface of the distal end portion of the catheter shaft.Type: ApplicationFiled: March 20, 2024Publication date: July 11, 2024Inventor: Greg Olson
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Publication number: 20240226547Abstract: Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit and control circuitry configured to control delivery of the one or more electric fields from the electric field generating circuit to the site of the cancerous tissue. An implantable lead is included having a lead body including a first electrical conductor disposed within the lead body, and a first electrode coupled to the lead body, the first electrode in electrical communication with the first electrical conductor, wherein the first electrical conductor forms part of an electrical circuit by which the electric fields from the electric field generating circuit are delivered to the site of the cancerous tissue, and the first electrode can include a conductive coil filar disposed around the lead body. Other embodiments are also included herein.Type: ApplicationFiled: December 18, 2023Publication date: July 11, 2024Inventors: Brian L. Schmidt, Devon N. Arnholt, Keith R. Maile, Sarah Melissa Gruba, William J. Linder
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Publication number: 20240226548Abstract: A stimulation system comprising: an implantable lead having a proximal end and a distal end, and at least one electrode along its distal end; an implantable neuromodulation stimulator disposed along the proximal end of the implantable lead; and an external device comprising a battery, a transmitter, and an antenna. The implantable lead is integral to the implantable neuromodulation stimulator. Methods of providing stimulation are also described.Type: ApplicationFiled: August 21, 2023Publication date: July 11, 2024Inventors: Lakshmi Narayan MISHRA, Lee Fason HARTLEY, James C. MAKOUS, Andre CASTILLO, Christopher LINDEN
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Publication number: 20240226549Abstract: Systems and methods for implementation of a disposable miniaturized implant for treatment of Post-Operative Ileums (POI), a miniaturized implant for treating chronic GI dysmotility (e.g., dysphagia, gastroesophageal reflux disease (GERD), nausea, functional dyspepsia, blockage of transit, and gastroparesis, inflammatory bowel disease) and obesity, by providing electrical stimulation to the part of bowel going through surgery to expedite the healing process while recording the smooth muscle activities simultaneously, or providing stimulation on a treatment location of the GI tract or the branch of the vagus nerve. Systems and methods are also provided for non-invasive, transcutaneous stimulation of anatomy within the abdomen of the patient.Type: ApplicationFiled: November 1, 2023Publication date: July 11, 2024Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Yi-Kai Lo, Wentai Liu
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Publication number: 20240226550Abstract: A system for controlling blood pressure includes a wearable interface having an internal contact surface, the wearable interface configured to at least partially encircle a first portion of a first limb of a subject, a sensing module carried by the wearable interface and configured to determine at least a change in blood pressure of the first limb of the subject, and an energy application module carried by the wearable interface and configured to apply energy of two or more types to the first limb of the subject.Type: ApplicationFiled: December 27, 2023Publication date: July 11, 2024Inventors: SHAHRAM MOADDEB, FAIZAL ABDEEN, RINDA SAMA
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Publication number: 20240226551Abstract: A system for controlling delivery of electrical stimulation to a subject. The system comprises a control device configured to send stimulation instructions to an electrical stimulation generator to cause the electrical stimulation generator to deliver transcranial electrical stimulation to one or more electrodes arranged to be positioned in proximity to a targeted region of the brain of the subject. The stimulation instructions comprise stimulation parameter value(s). The control device is configured to receive sensor data from optical sensor(s) arranged to be positioned in proximity to the targeted region and transmit updated stimulation instructions comprising updated simulation parameter value(s) to the electrical stimulation generator to cause the electrical stimulation generator to modify characteristic(s) of the stimulation. The system is configured to analyse the sensor data to determine an activity measure and determine updated stimulation parameter value(s) based on the determined activity measure.Type: ApplicationFiled: December 22, 2023Publication date: July 11, 2024Inventors: Nathalie GOUAILHARDOU, Damian SOFREVSKI
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Publication number: 20240226552Abstract: The present disclosure relates to neuromodulation, and in particular to devices and techniques for delivering non-invasive neurostimulation to treat enuresis. Particularly, aspects of the present disclosure are directed to medical device comprising a transcutaneous electrical nerve stimulation (TENS) device comprising an electronics module comprising: a controller configured to provide a set of stimulation parameters, and a pulse generator configured to generate neural stimulation based on the set of stimulation parameters. The medical device also includes one or more electrodes connected to the TENS device for delivering the neural stimulation generated by the pulse generator to a perineal region of a user, one or more gel pads for adhering the electrodes to the perineal region of the user, one or more sensors for detecting a triggering event for the neural stimulation, and a pad attached to the TENS device, the electrodes, the sensors, and the gel pads.Type: ApplicationFiled: October 23, 2023Publication date: July 11, 2024Applicant: Global Continence, Inc.Inventors: Andrew Kirsch, Ubirajara De Oliveira Barroso Júnior
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Publication number: 20240226553Abstract: Systems, devices, and methods for neurostimulation via vestibular stimulation are described. One example is a device for administering thermal stimulation to an ear canal of a subject. The device may include an earpiece configured to be at least partially insertable into the ear canal of the subject; a thermoelectric device thermally coupled to the earpiece and configured to heat and/or cool the earpiece to thereby heat and/or cool the ear canal of the subject; and a controller configured to administer a selected treatment plan including administering a caloric vestibular stimulation (CVS) stimulus to the ear canal of the subject in a condition-treatment effective amount during a first treatment interval. The treatment plan may be effective to produce a durable improvement in at least one symptom of the condition for a time of at least 1 week following cessation of the administering.Type: ApplicationFiled: October 17, 2023Publication date: July 11, 2024Inventors: Robert D. Black, Lanty L. Smith, Lesco L. Rogers
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Publication number: 20240226554Abstract: A computer-implemented method is provided for modifying a stimulation artefact in a measured electrical response of a subject to a stimulus. The method comprises: i) providing a first and a second signal. The first signal is a signal used as stimulus or a time-dependent signal derived from the stimulus and the second signal is a signal obtained as the measured electrical response to the stimulus; ii) determining a stimulus-response mapping between the first signal and the second signal; iii) identifying a feature of the determined stimulus-response mapping corresponding to the stimulation artefact; iv) determining a predicted electrical response corresponding to the identified feature of the determined stimulus-response mapping; and v) subtracting the predicted electrical response from the second signal to obtain a stimulation artefact modified measured electrical response.Type: ApplicationFiled: December 22, 2021Publication date: July 11, 2024Inventors: Tom FRANCART, Ben SOMERS
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Publication number: 20240226555Abstract: Illustrative methods and devices for providing stimulus to the eye to treat vision disorders. Systems and methods for testing thresholds and configuring the stimulation for a patient are provided. Various examples may include therapies for vision disorders that can progress to blindness, such as macular degeneration or other diseases and disease processes.Type: ApplicationFiled: October 20, 2023Publication date: July 11, 2024Inventors: James R. Chiapetta, Paul Rockley, Ronald Schuchard
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Publication number: 20240226556Abstract: This disclosure provides an SCS system comprised of an adaptive IPG. The IPG selectively chooses certain burst pulse parameters according to a pattern of frequencies and amplitudes that are determined by a low power hardware circuit. Alternatively, the patterns of frequencies and amplitudes are dictated by a predetermined list of parameters from a table of limited length. The IPG also is capable of receiving and storing vital sign telemetry, and spinal cord position to train an adaptive neural network to produce paresthesia pulses. Training of the IPG takes place after closing. Retraining the neural network allows the system to adapt to habituation, lead migration, and physiological changes in the patient's condition to maintain efficacy of the system over time. Training the neural network is also accomplished outside the IPG by a separate processor, which serves to conserve battery power and facilitate frequent retraining.Type: ApplicationFiled: January 10, 2024Publication date: July 11, 2024Applicant: Wavegate CorporationInventor: Erich W. Wolf, II
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Publication number: 20240226557Abstract: A system for performing spinal cord stimulation on a subject is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be minimally invasively inserted to a target stimulation site within the nervous tissue, includes stimulation electrodes. The processor is configured to receive more recorded signals from the recording arrays at the target recording site, determine an electrophysiological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the determined electrophysiological state in order to affect the electrophysiological state.Type: ApplicationFiled: October 20, 2023Publication date: July 11, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Craig H. MERMEL, Daniel TRIETSCH, Mark HETTICK, Elton HO, Kazutaka TAKAHASHI
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Publication number: 20240226558Abstract: Methods and systems for testing and treating spinal cord stimulation (SCS) patients are disclosed. Patients are eventually treated with sub-perception (paresthesia free) therapy. However, supra-perception stimulation is used during “sweet spot searching” during which active electrodes are selected for the patient. This allows sweet spot searching to occur much more quickly and without the need to wash in the various electrode combinations that are tried. After selecting electrodes using supra-perception therapy, therapy is titrated to sub-perception levels using the selected electrodes. Such sub-perception therapy has been investigated using pulses at or below 10 kHz, and it has been determined that a statistically significant correlation exists between pulse width (PW) and frequency (F) in this frequency range at which SCS patients experience significant reduction in symptoms such as back pain.Type: ApplicationFiled: March 21, 2024Publication date: July 11, 2024Inventors: Que T. Doan, Jianwen Gu, Ismael Huertas Fernandez, Rosana Esteller, Michael A. Moffitt
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Publication number: 20240226559Abstract: The cure for Bell's palsy and Ramsay Hunt syndrome comprised individual series of electrical stimulus for relieving the compression of ipsilateral facial nerve in its facial canal. The compositions of selfies and related avatars of patients recommending frequencies, durations and numbers of individual treatment sessions for achieving full recovery and digital blockchains managing the cure among patients.Type: ApplicationFiled: October 25, 2022Publication date: July 11, 2024Inventor: Anuthep Benja-Athon
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Publication number: 20240226560Abstract: Systems, devices, and methods are disclosed for computer-assisted goal setting and tracking with respect to neuromodulation device treatment. A digital health system includes a user-interface device to receive a user input about a personalized objective of neuromodulation treatment or an intended manner of using the neuromodulation device by the patient. The user input can be in forms of text, voice, or other unstructured or unclassified data formats. A controller circuit can process the user input using analytical methods including natural language processing to generate a personalized treatment and device usage goal, and track the progress toward the personalized treatment and device usage goal using patient state information. The tracked progress may be presented to the patient, or be used to initiate or adjust a neuromodulation therapy.Type: ApplicationFiled: October 16, 2023Publication date: July 11, 2024Inventors: Kyle Harish Srivastava, Amarpreet Singh Bains, Benjamin Phillip Hahn
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Publication number: 20240226561Abstract: Methods and systems for assisting a patient to reprogram parameters of an implantable medical device, such as a spinal cord stimulator, are disclosed. A patient may use an external controller, which may be either a dedicated device or a personal computing device, to interact with their implantable medical device and evaluate the efficacy of their therapy. If the efficacy diminishes, the patient may use their external controller to adjust either the neural dosage (i.e., frequency, pulse width, and/or amplitude) and/or the location at which stimulation is provided. A reprogramming assistant is provided, which guides the patient in adjusting their stimulation using their external controller. The patient may use supra-perception or sub-perception stimulation for the adjustment. The implantable medical device may include pre-programmed “rescue programs” to assist the patient in recovering the efficacy of their therapy.Type: ApplicationFiled: March 20, 2024Publication date: July 11, 2024Inventors: Ismael Huertas Fernandez, Que T. Doan
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Publication number: 20240226562Abstract: One aspect of the present disclosure relates to a system for treating a medical condition in a patient. The system can include a neurostimulator that is in electrical communication with a remote transducer. The neurostimulator can be sized and dimensioned for injection or insertion into a pterygopalatine fossa (PPF) of a patient. The remote transducer, when activated and brought into close proximity to the patient's head, can cause the neurostimulator to deliver an electrical signal to a target neural structure located within the PPF to treat the medical condition.Type: ApplicationFiled: December 18, 2023Publication date: July 11, 2024Inventors: William Hsu, Anthony Caparso, Thomas Luhrs, Ian G. Welsford, Mark Van Kerkwyk, Vimal Ganesan
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Publication number: 20240226563Abstract: A system is provided for informing a therapeutic procedure. In some embodiments, the system may be configured to determine specific states associated with a sleep-wake cycle of a patient. Additionally, the system may be configured to measure one or more signals with cardiac activity of the patient upon detecting the specific states of the sleep-wake cycle of the patient. Subsequently, the system may be configured to determine one or more parameters for applying an electrical signal to an anatomical element of the patient based on the one or more signals with cardiac activity. In some embodiments, the system may be configured to establish a longitudinal trend of cardiac metrics for the patient based on a plurality of signals with cardiac activity for the patient measured during the specific states of the sleep-wake cycle across a plurality of days.Type: ApplicationFiled: September 22, 2023Publication date: July 11, 2024Inventors: Malgorzata Maria Straka, Annemarie K. Brinda, Juan G. Hincapie, Leonid M. Litvak, Jerel Keith Mueller, Joshua James Nedrud, Andrew Jay Cleland, Aleksandra Pavlovna Kharam
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Publication number: 20240226564Abstract: The disclosure provides systems and methods for treating obstructive sleep apnea using an acoustic sensor configured to detect acoustic sounds generated by the heart and lungs. Sensory data from the acoustic sensor is used by an implanted stimulation system to determine when to deliver electrical stimulation to a nerve which innervates an upper airway muscle, such as the hypoglossal nerve, to treat sleep apnea.Type: ApplicationFiled: February 16, 2024Publication date: July 11, 2024Inventors: Brian M. Shelton, Sahar Elyahoodayan, Harshit R. Suri
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Publication number: 20240226565Abstract: A flexible electrode array with hundreds or thousands channels for clinical use includes an array of at least hundreds of electrodes on a flexible biocompatible polymer substrate. Perfusion through holes are provided through the substrate. Individual elongate leads connect to each of the electrodes, the elongate lead connections being supported by the flexible biocompatible polymer substrate and extending away from the array. Flexible biocompatible polymer insulates the individual elongate lead connections and supporting the array. An interposer with individual channel connections is conductively bonded to the individual elongate lead connections. Sterile bag packaging encloses a portion of the interposer, where the outer side of the package including the array and individual elongate lead is sterile while the inner side of the packaging is non-sterile. The portion interposer inside the package is configured to connect to a circuit board within the packaging.Type: ApplicationFiled: March 10, 2022Publication date: July 11, 2024Inventors: Shadi A. Dayeh, Youngbin Tchoe, Andrew M. Bourhis
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Publication number: 20240226566Abstract: Systems and methods for generating and/or applying an adjustment for one or more parameters of a neuromodulation therapy of a user are provided. One or more physiological-based inputs of the user may be received and a therapy response score may be determined based on the one or more physiological-based inputs. At least one adjustment for one or more parameters of the neuromodulation therapy may be generated based on the therapy response score.Type: ApplicationFiled: October 17, 2023Publication date: July 11, 2024Inventors: Malgorzata Maria Straka, Annemarie K. Brinda, Juan G. Hincapie, Leonid M. Litvak, Jerel Keith Mueller, Joshua James Nedrud, Andrew Jay Cleland, Aleksandra Pavlovna Kharam, Ashwini D. Sharan
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Publication number: 20240226567Abstract: Described herein are implantable closed-loop neuromodulation devices, systems that includes such devices and an interrogator configured to emit ultrasonic waves that power the device, methods of using such devices and systems, and methods of modulating neural activity. The implantable device can include one or more curved members extending from a body. The curved members are configured to at least partially circumscribe a nerve, and include one or more electrode pads. The body includes an ultrasonic transducer configured to receive ultrasonic waves and convert energy from the ultrasonic waves into an electrical energy; and a computational circuit configured to receive a detection signal based on a detected electrophysiological signal, generate a stimulation signal based on the detection signal, and operate the electrode pads of to emit an electrical pulse to the nerve based on the stimulation signal.Type: ApplicationFiled: January 16, 2024Publication date: July 11, 2024Inventors: Jose M. CARMENA, Michel M. MAHARBIZ, Ryan NEELY
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Publication number: 20240226568Abstract: Methods and systems for closed loop feedback control of electrical neuromodulation are described. Closed loop feedback control is based on sensed electrical potentials, which are used as reference control variables in a feedback control algorithm to adjust the electrical stimulation based on one or more control algorithm parameters. The performance of the closed loop feedback control algorithm may be evaluated, and the feedback algorithm may be adjusted based on its performance. In some instances, the feedback algorithm may be adjusted based on an indication state of the patient.Type: ApplicationFiled: December 21, 2023Publication date: July 11, 2024Inventors: Andrew Haddock, Adarsh Jayakumar, Max Witwer, Keron Greene
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Publication number: 20240226569Abstract: The disclosure provides systems and methods for treating sleep-disordered breathing (e.g., obstructive sleep apnea) using a system comprising an inertial measurement unit (IMU) which includes an accelerometer and/or a gyroscope, wherein the IMU is configured to detect movement by a human subject and to generate data based on the detected movement. Positional and/or movement data generated by the IMU is used by a stimulation system to detect gross movement by the subject, and to deliver electrical stimulation to a nerve which innervates an upper airway muscle (e.g., a hypoglossal nerve) in response to the detection of gross movement, in order to treat the subject.Type: ApplicationFiled: October 18, 2023Publication date: July 11, 2024Inventors: Brian MECH, Brian M. Shelton, Neil H. Talbot
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Publication number: 20240226570Abstract: A system for performing deep brain stimulation on a brain of a patient is disclosed. The system comprises one or more recording arrays, at least one stimulation array, and a processor. The recording arrays, which may be minimally invasively inserted to a target recording site of the brain, include recording electrodes having a diameter of less than about 1 mm and having a spacing of less than about 1 mm therebetween. The stimulation array, which may be inserted to a target stimulation site within the deep brain, includes at least one stimulation electrode. The processor is configured to receive one or more recorded signals from the recording arrays at the target recording site, determine a neurological state of the brain based on the recorded signals, and deliver electrical stimulation to the target stimulation site through the stimulation array based on the neurological state in order to electrically stimulate the brain.Type: ApplicationFiled: October 20, 2023Publication date: July 11, 2024Applicant: PRECISION NEUROSCIENCE CORPORATIONInventors: Benjamin I. RAPOPORT, Craig H. MERMEL, Mark HETTICK, Elton HO
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Publication number: 20240226571Abstract: A system may include a medical device and at least one external device. The medical device may have a plurality of electrodes, and may be configured to measure impedance for each of the plurality of electrodes and generate impedance data. The eternal device(s) may include a display and a processor. The medical device may be configured to communicate the generated impedance data to the at least one eternal device. The processor may be configured to provide on the display a plurality of electrode icons corresponding to the plurality of electrodes, to determine, based on the impedance data, one or more impedance state electrodes from the plurality of electrodes that have an impedance state, and to provide on the display an impedance status representation for one or more of the plurality of electrode icons corresponding to the one or more impedance state electrodes.Type: ApplicationFiled: January 5, 2024Publication date: July 11, 2024Inventor: Mitchell A. Tramp
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Publication number: 20240226572Abstract: A neuromodulation device configured to operate in a plurality of waveform generation modes includes a power source, a control unit in communication with the power source, a bipolar current generator in communication with the control unit and an input of a switching unit, and a plurality of electrodes. Each electrode is in communication with a unique output of the switching unit. The switching unit can provide electrical communication between the bipolar current generator and a selected one of the plurality of electrodes in response to a control signal from the control unit. The current generator can deliver alternating current to the at least one working electrode during a first waveform generation mode and direct current to the working electrode during a second waveform generation mode. An indifferent electrode provides a return path for the alternating current, the direct current, or both.Type: ApplicationFiled: May 26, 2022Publication date: July 11, 2024Inventors: Michael A. Faltys, Aaron Hardinger, James Harris, Thomas Flores, Douglas Michael Ackermann, Kenneth S. Wu
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Publication number: 20240226573Abstract: Devices, systems, or methods include generating, by stimulation generation circuitry, a first train of electrical stimulation pulses at a first frequency to a first target tissue; and generating, by the stimulation generation circuitry, a second train of electrical stimulation pulses at a second frequency to a second target tissue different from the first target tissue, wherein at least some electrical stimulation pulses of the first train of electrical stimulation pulses are interleaved with at least some electrical stimulation pulses of the second tram of electrical stimulation pulses. At least the first target tissue is associated with a spinal cord of a patient, and the second target tissue is associated with at least one of a peripheral nerve or a nerve root of the patient.Type: ApplicationFiled: February 24, 2022Publication date: July 11, 2024Inventors: Brooke G. Kelley, Juan G. Hincapie, Andrew J. Cleland
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Publication number: 20240226574Abstract: Devices, systems, and techniques are described for selecting parameters for electrical stimulation therapy. For example, device may include processing circuitry configured to determine a first window of time to sense a physiological signal, determine, based on the first window of time, a second window of time for delivering electrical stimulations, and determine, based on a duration of the second window of time, a number of stimulation pulses deliverable during the second window of time at one or more pulse frequencies. The processing circuitry may then output, based on the number of stimulation pulses deliverable during the second window of time, at least one selectable stimulation parameter that at least partially defines the electrical stimulation, wherein the second window of time is adjacent to the first window of time.Type: ApplicationFiled: February 24, 2022Publication date: July 11, 2024Inventor: Scott A. Hareland
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Publication number: 20240226575Abstract: A leadless cardiac pacemaker (LCP) may include a three-axis accelerometer. Acceleration signals from each of the three axes of the accelerometer may be combined into a combined acceleration signal and a predetermined morphological feature may be identified in a magnitude of the combined acceleration signal. The relative timing of the predetermined morphological signal relative to the cardiac cycle duration may be used to ascertain whether a detected arrhythmia is an arrhythmia that should be treated by the LCP or should not be treated by the LCP.Type: ApplicationFiled: January 4, 2024Publication date: July 11, 2024Applicant: CARDIAC PACEMAKERS, INC.Inventors: Steven Lee Eddy, Michael J. Kane, Bryan J. Swackhamer
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Publication number: 20240226576Abstract: Systems and methods for electrically stimulating a patient's cardiac conduction system at selected locations based on heart sounds are disclosed. A medical-device system includes a data receiver to receive heart sound information sensed from a patient, an electrostimulation circuit to deliver electrostimulation to the cardiac conduction system, and a controller circuit to generate, from the heart sound information sensed in response to the electrostimulation being delivered respectively to two or more candidate locations at or near the cardiac conduction system, heart sound metrics respectively for the two or more candidate locations. Based on the heart sound metrics, the controller circuit selects at least one of the candidate locations as a pacing location for subsequent electrostimulation. Electrostimulation can be delivered to the selected pacing location to restore cardiac synchrony.Type: ApplicationFiled: December 20, 2023Publication date: July 11, 2024Inventors: Pramodsingh Hirasingh Thakur, Kevin Chu, Viktoria A. Averina
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Publication number: 20240226577Abstract: A communication system for wireless data transmission between an implantable medical device (IMD) and an external device and a respective communication method are disclosed aiming at the increase of longevity of an IMD energy source. The communication system comprises a communication unit and a processor. The IMD is configured to monitor a bodily parameter of a patient and/or is configured to deliver a therapy signal to the patient, wherein the IMD comprises a transceiver module configured to exchange the data with the communication unit of the external device in an uplink direction from the transceiver module to the communication unit and in a downlink direction from the communication unit to the transceiver module. Further, a respective computer program product and computer readable data carrier is described.Type: ApplicationFiled: June 8, 2022Publication date: July 11, 2024Applicant: BIOTRONIK SE & Co. KGInventors: Joachim ELSNER, Juergen KOEPPEL, Emanuel BIERSCHNEIDER, Wolfgang GARTZ, Uwe KAMENZ, Uwe STUERMER, Enrico STEPHAN, Gunnar GORECKI
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Publication number: 20240226578Abstract: The present invention relates to a method for controlling the operation of at least two implantable medical devices for stimulating a human or animal heart, the method comprising the following steps: a) receiving, with a control device, a first operational parameter of a first device of the at least two implantable medical devices; b) receiving , with the control device, a second operational parameter of a second device of the at least two implantable medical devices; c) automatically checking whether there exists a conflict between the first operational parameter and the second operational parameter precluding a safe operation of the first device and the second device; and d) if a conflict has been identified, visualizing the first operational parameter, the second operational parameter, and data on the conflict on a display of the control device.Type: ApplicationFiled: May 25, 2022Publication date: July 11, 2024Applicant: BIOTRONIK SE & Co.KGInventors: Thomas DOERR, Dirk MUESSIG
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Publication number: 20240226579Abstract: A system is provided for identifying and reducing noise in a therapeutic procedure. For example, the system may be configured to measure one or more signals with cardiac activity. The system may be configured to then identify one or more sources of noise that are distorting the one or more signals with cardiac activity and may reduce the one or more sources of noise from the one or more signals with cardiac activity. Subsequently, the system may be configured to determine one or more aggregate cardiac-derived metrics and/or save processed cardiac data based on the one or more signals with cardiac activity with the one or more sources of noise reduced. Additionally, the system may be configured to determine one or more parameters for applying an electrical signal to an anatomical element of a patient based on the one or more aggregate cardiac-derived metrics and/or saved processed cardiac data.Type: ApplicationFiled: September 27, 2023Publication date: July 11, 2024Inventors: Malgorzata Maria Straka, Annemarie K. Brinda, Juan G. Hincapie, Leonid M. Litvak, Jerel Keith Mueller, Joshua James Nedrud, Andrew Jay Cleland, Aleksandra Pavlovna Kharam, David A. Dinsmoor
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Publication number: 20240226580Abstract: The invention is directed to a communication system for a wireless message transfer between an implantable medical device (IMD) and an external device, comprising an IMD and an external device, wherein the IMD is configured to monitor the health status of a patient and/or configured to deliver a therapy signal to the patient, wherein the IMD comprises a processor, a memory module and a transceiver module configured to bi-directionally exchange the messages with the external device. In order to provide a communication system and method that enables a low-overhead means for supporting communication with a plurality of IMDs and facilitating targeted IMD-specific interactions as part of IMD assembly and in-clinic use, the external device is configured to send a predefined wake-up signal to the transceiver module of the IMD combined with an ID request message following the wake-up signal within a predefined first time interval.Type: ApplicationFiled: May 11, 2022Publication date: July 11, 2024Applicant: BIOTRONIK SE & Co. KGInventors: Brian M. TAFF, Kurt SWENSON, Dean BERGSTROM, Julian MERLIN, Brad MCMILLAN
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Publication number: 20240226581Abstract: A surgical method of treating reflux disease comprising the steps of dissecting the fundus at least partially down on the posterior side thereof; in the approximate direction towards bursa Omentalis, as well as away from the spleen. The method further comprising the steps of dissecting the esophagus such that the esophagus is disconnected from the surrounding tissue at least 3 cm in a cranial direction from the angle of his and connecting the fundus to the esophagus by placing at least two posterior single sutures in a posterior suture line, or a posterior continuous suture line, connecting the fundus to the esophagus, on the sinister-posterior side of the esophagus, and placing at least two anterior sutures, in an anterior suture line, or an anterior continuous suture line, connecting the fundus to the esophagus, on the sinister-anterior side of the esophagus.Type: ApplicationFiled: January 5, 2024Publication date: July 11, 2024Inventor: Peter Forsell