Patents Issued in August 20, 2024
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Patent number: 12065371Abstract: A system and process for forming a curved glass laminate article is provided. The process and system utilizes co-sagging of a stack of glass sheets of different thicknesses and different glass materials. During co-sagging the thicker glass layer is placed on top of the thinner glass layer. In this process, shape mismatch is avoided by selecting/controlling the glass materials of the sheets of glass such that the viscosity of the lower, thinner sheet during co-sagging is greater than the viscosity of the thicker glass sheet.Type: GrantFiled: October 5, 2018Date of Patent: August 20, 2024Assignee: CORNING INCORPORATEDInventors: Douglas Dale Bressler, Anurag Jain, Zheming Zheng
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Patent number: 12065372Abstract: Techniques for making glass components for electronic devices are disclosed. The techniques disclosed can be used to shape a glass workpiece to form a three-dimensional glass component, such as a glass cover member. Glass components and enclosures and electronic devices including the glass components are also disclosed.Type: GrantFiled: December 16, 2021Date of Patent: August 20, 2024Assignee: APPLE INC.Inventors: Andrew J. Meschke, Thomas Johannessen
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Patent number: 12065373Abstract: Provided is an elongating method for elongating a glass base material by heating the same while moving the same downward within an elongating apparatus, the glass base material including a transparent tapered section, wherein the transparent tapered section is located at an upper end of the glass base material and has an end face to which a suspension dummy formed from a glass pole is welded, the elongating method comprising steps for: starting to elongate the glass base material by heating the same, starting from a lower-end side thereof, by causing the glass base material to pass through a range within the elongating apparatus in which a preset elongating process temperature or higher is maintained; and after the tapered section enters the range, ending the elongating of the glass base material before the end face enters the range.Type: GrantFiled: January 18, 2022Date of Patent: August 20, 2024Assignee: Shin-Etsu Chemical Co., Ltd.Inventor: Ryo Mitta
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Patent number: 12065374Abstract: A method for producing an electronic structure on a glass pane which has, at least on one of its two glass pane surfaces, a functional coating having at least one electrically conductive functional layer, preferably having multiple electrically conductive functional layers, the functional coating being structured by applying laser radiation in such a way that the electronic structure, preferably a capacitive sensor system or a conductor loop, is created. A glass sheet having at least one glass pane of this type.Type: GrantFiled: October 18, 2019Date of Patent: August 20, 2024Assignee: HEGLA boraident GmbH & Co. KGInventors: Bernhard Hötger, Heinrich Ostendarp, Thomas Rainer
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Patent number: 12065375Abstract: This disclosure describes substrate(s) having a three-dimensional (3D) feature formed thereon and methods of forming the features. One method involves applying a first layer of UV-curable material on a surface of the glass container around a circumference of the container and curing the first layer of UV-curable material to produce a first cured material layer that forms at least a portion of a first 3D feature. The method further comprises applying a second layer of UV-curable material on the surface of the glass container, spaced apart from the first 3D feature, around the circumference of the container, and curing the second layer of UV-curable material to produce a second cured material layer that forms at least a portion of a second 3D feature. The portion of the glass container between the first and second 3D features has a circumference less than that of the first or second 3D features.Type: GrantFiled: January 27, 2023Date of Patent: August 20, 2024Assignee: Owens-Brockway Glass Container Inc.Inventors: Brian J. Chisholm, Cedric Charretton, Olivier Dangmann, Eva Mifsud, Susan L. Smith, Ludovic Valette
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Patent number: 12065376Abstract: The present invention relates to a chemically strengthened glass having a thickness t (mm), in which a first-order derivative CSx? of a stress value CSx (MPa) is ?4.7 or larger in a range of CSx?0 in a profile of the stress value CSx (MPa), in which the stress value CSx (MPa) is a function of depth×(?m) from a glass surface, and in which the stress value CSx (MPa) is measured by a scattered light photoelastic stress meter, and a manufacturing method thereof.Type: GrantFiled: February 25, 2022Date of Patent: August 20, 2024Assignee: AGC INC.Inventors: Kaname Sekiya, Yusuke Fujiwara
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Patent number: 12065377Abstract: A cement slurry including graphene, a cementitious material, and water; the graphene comprises bioderived renewable graphene (BRG). The cement slurry can comprise from about 0.01 to about 20, from about 0.1 to about 15, from about 0.5 to about 5 percent graphene by weight of cementitious material (% graphene bwoc). The cement slurry can have enhanced stability, as evidenced by a uniform density of the slurry and a reduction in free fluid, according to API 10B-2, relative to a same cement slurry absent the graphene.Type: GrantFiled: August 22, 2022Date of Patent: August 20, 2024Assignee: Halliburton Energy Services, Inc.Inventors: Samuel J. Lewis, Thomas Jason Pisklak, Claudia Pineda
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Patent number: 12065378Abstract: A method for preparing low-background cement includes: uniformly mixing a seed crystal of cement, C4AF whiskers, and high-magnesium raw material to yield a first mixture, calcining the first mixture at 1400-1500° C., to yield a low-background clinker, the first mixture including 1.0-5.0 wt. % of the seed crystal of cement, 1.0-5.0 wt. % of the C4AF whiskers, and the balance is the high-magnesium raw material; and grinding a second mixture of the low-background clinker and gypsum, to yield low-background cement. The seed crystal of cement is a high-magnesium and low hydration heat clinker, has a specific activity of Ra-226 radioactive nuclides within 50 Bq/kg, and the MgO content of the clinker is between 4.0 wt. % and 5.0 wt. %, with 50 wt. %?C3S?55.0 wt. %; and the high-magnesium raw material has a MgO content between 2.5 wt. % and 3.0 wt. %.Type: GrantFiled: May 12, 2023Date of Patent: August 20, 2024Assignee: CHINA BUILDING MATERIALS ACADEMY CO., LTD.Inventors: Wen Huang, Yang Yu, Min Wang, Zhaijun Wen, Tingting Bao, Guang Yao, Xin Shen, Yun Liu, Jing Wang, Xianbin Wang, Zhongcheng Ma, Xianshu Gao, Kunyue Zhang, Guanbao Tang, Suihua Guo, Mingming Sun, Ao Liu
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Patent number: 12065379Abstract: Various embodiments include cementitious compositions with low levels of embodied greenhouse gas emissions, in particular carbon dioxide, as a result of its production and/or use compared to conventional cementitious materials, such as portland cement. Various embodiments include any cementitious material or materials with low embodied carbon, as well as any material produced using this cement.Type: GrantFiled: November 21, 2023Date of Patent: August 20, 2024Assignee: Sublime Systems, Inc.Inventors: Jesse D. Benck, Yet-Ming Chiang, Kyle Dominguez, Leah D. Ellis, Khashayar Jafari, Mariya Layurova, Ada MacLeod
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Patent number: 12065380Abstract: A method for forming an oxidation protection system on a composite structure may comprise: applying a ceramic layer slurry to the composite structure, wherein the ceramic layer slurry comprises aluminum and silicon in a solvent or carrier fluid; and heating the composite structure in an environment comprising nitrogen gas and oxygen gas to form a ceramic layer on the composite structure, wherein the ceramic layer comprises aluminum nitride and alumina.Type: GrantFiled: November 16, 2021Date of Patent: August 20, 2024Assignee: GOODRICH CORPORATIONInventor: Atta Khan
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Patent number: 12065381Abstract: Disclosed herein are embodiments of high Q, temperature stable materials with low dielectric constants. In particular, a two-phase material can form based on the rutile phase of titanium oxide along with a spinel structure of ZnAl2O4. This material can have a dielectric constant below 15 which is simultaneously temperature stable.Type: GrantFiled: July 10, 2020Date of Patent: August 20, 2024Assignee: Skyworks Solutions, Inc.Inventors: Michael David Hill, Srinivas Polisetty
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Patent number: 12065382Abstract: An environmental barrier coating includes a barrier layer which includes a matrix, diffusive particles, and gettering particles; and a calcium-magnesia alumina-silicate (CMAS)-resistant component. The CMAS-resistant component includes hafnium silicate and a rare earth hafnate. An article and a method of fabricating an article are also disclosed.Type: GrantFiled: May 7, 2021Date of Patent: August 20, 2024Assignee: RTX CorporationInventors: Richard Wesley Jackson, James T. Beals, Xia Tang, David A. Litton, Elisa M. Zaleski, Brian T. Hazel
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Patent number: 12065383Abstract: An oriented ceramic sintered body production method includes (a) a step of preparing a ceramic compact before firing into an oriented ceramic sintered body; and (b) a step of obtaining an oriented ceramic sintered body by sandwiching the ceramic compact between a pair of releasing sheets, placing the ceramic compact and the releasing sheets in a hot press firing furnace, and hot press firing the ceramic compact while applying a pressure by a pair of punches through the pair of releasing sheets, wherein each of the releasing sheets is a releasing sheet such that, after the releasing sheet is sandwiched between PET films, is then placed and vacuum-packed on a stainless steel sheet, and is isostatically pressed at 200 kg/cm2, a surface of the releasing sheet on the side opposite from the stainless steel sheet has a profile curve with a total profile height Pt of 0.8 ?m or less.Type: GrantFiled: March 13, 2020Date of Patent: August 20, 2024Assignee: NGK INSULATORS, LTD.Inventors: Morimichi Watanabe, Kei Sato, Kiyoshi Matsushima, Takahiro Maeda, Jun Yoshikawa, Tsutomu Nanataki
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Patent number: 12065384Abstract: Methods of firing ceramic honeycomb bodies are disclosed that include placing refractory particles on and end face of the green ceramic honeycomb body, and heating the green ceramic honeycomb body to a temperature of at least 600° C. to form a fired ceramic honeycomb body. The refractory particles prevents sticking of honeycomb-to-honeycomb during firing. A layer of refractory particles can also be used to replace a green cookie.Type: GrantFiled: November 15, 2019Date of Patent: August 20, 2024Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Andrea Marie Muller-Hoff, Douglas Richard Wing
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Patent number: 12065385Abstract: A ceramic-copper composite having a flat plate shape, including: a ceramic layer; a copper layer; and a brazing material layer present between the ceramic layer and the copper layer. When a region having a length of 1,700 ?m in a long-side direction is a region P on a cut surface of the ceramic-copper composite obtained when the ceramic-copper composite is cut with a plane perpendicular to a main surface of the ceramic-copper composite, an average crystal grain size D1 of copper crystals at least partially present in a region P1 within 50 ?m on a side of the copper layer from an interface between the ceramic layer and the brazing material layer in the region P is 30 ?m or more and 100 ?m or less.Type: GrantFiled: November 22, 2019Date of Patent: August 20, 2024Assignee: DENKA COMPANY LIMITEDInventors: Akimasa Yuasa, Takahiro Nakamura, Shuhei Morita, Koji Nishimura
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Patent number: 12065386Abstract: A method for forming a super-insulating material for a vacuum insulated structure for an appliance includes disposing hollow glass spheres within a rotating drum, wherein a plurality of interstitial spaces are defined between the hollow glass spheres. An anchor material is disposed within the rotating drum. The hollow glass spheres and the anchor material are rotated within the rotating drum, wherein the anchor material is mixed with the hollow glass spheres to partially occupy the interstitial spaces. A silica-based material is disposed within the rotating drum. The silica-based material is mixed with the anchor material and the hollow glass spheres to define a super-insulating material, wherein the silica-based material attaches to the anchor material and is entrapped within the interstitial spaces. The silica-based material and the anchor material occupy substantially all of an interstitial volume defined by the interstitial spaces.Type: GrantFiled: June 12, 2023Date of Patent: August 20, 2024Assignee: WHIRLPOOL CORPORATIONInventors: Lakshya J. Deka, Eric J. Vasko
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Patent number: 12065387Abstract: A process for manufacturing a porous abradable coating includes: filling a mold with hollow glass or thermosetting polymer beads and a slurry; and sintering heat treatment to obtain a ceramic layer with pores. A maximum sintering temperature of the green body of the ceramic part is either higher than the melting temperature of the hollow glass beads so that at the end of the sintering heat treatment the hollow glass beads are melted, or higher than the decomposition temperature of the hollow thermosetting polymer beads so that at the end of the sintering heat treatment the hollow thermosetting polymer beads are decomposed.Type: GrantFiled: October 9, 2019Date of Patent: August 20, 2024Assignee: SAFRAN AIRCRAFT ENGINESInventors: Philippe Charles Alain Le Biez, Nicolas Droz, Ludovic Philippe Liais, Serge Georges Vladimir Selezneff
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Patent number: 12065388Abstract: The present invention relates to a method for impregnating concrete with a non-aqueous electrolyte characterized in that an electric field is applied between electrodes mounted on the concrete surface and/or embedded in the concrete such that the non-aqueous electrolyte migrates into the concrete. Preferably, lithium ions are dissolved in the non-aqueous electrolyte.Type: GrantFiled: March 7, 2019Date of Patent: August 20, 2024Assignees: STRUCTURAL TECHNOLOGIES, INPROM ANSTALTInventors: Wolfgang Schwarz, Eyad Alhariri
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Patent number: 12065389Abstract: A fluid-bed granulator system may include a fluid-bed granulator, a scrubber unit, and a connection-duct between an air vent opening of the fluid-bed granulator and the scrubber unit. An inner surface of the connection-duct may be at least partially coated with an anti-adhesion layer. The system may further include a granulator space inside the fluid-bed granulator, a perforated plate disposed inside the granulator space, spray nozzles disposed at the perforated plate, a fluidization air inlet, supply lines for atomization air connected to the spray nozzles, supply lines for a liquid melt connected to the spray nozzles, a granulation seeds inlet, a granulator outlet opening, and an air vent opening. A disclosed urea granulation plant may utilize the fluid-bed granulator system.Type: GrantFiled: March 21, 2019Date of Patent: August 20, 2024Assignees: THYSSENKRUPP FERTILIZER TECHNOLOGY GMBH, thyssenkrupp AGInventors: Harald Franzrahe, Matthias Potthoff, Andreas Grulke
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Patent number: 12065390Abstract: An agricultural energising biostimulating composition made from sucrose, protein/hydrolised protein, and humic acid. The composition is aimed at solving the energy deficit that is affecting the production of fruit and vegetables in the agriculture industry. Plants do not obtain the energy they need for their development, which affects the quality and quantity of the fruit produced.Type: GrantFiled: November 17, 2020Date of Patent: August 20, 2024Assignee: POWER ROOTS SPAInventors: Maria del Pilar Barros Covarrubias, Alfredo Barros Opazo, Felipe Barros Opazo, Hernan Villalobos Barcelo, Eduardo Conca Calvo
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Patent number: 12065391Abstract: Reaction products and methods for making and using such reaction products are provided. For example, a reaction product comprising an adduct formed from urea, formaldehyde, and a urease inhibitor is described, which can be provided in various forms. For example, such a reaction product can be in the form of a solid or solution. Such a reaction product can also be combined with one or more additional components, including but not limited to, additional urease inhibitor and/or a nitrogen-based fertilizer composition.Type: GrantFiled: September 13, 2021Date of Patent: August 20, 2024Assignee: Koch Agronomic Services, LLCInventors: Douglas Barr, Ethel Garnier, Kwame Owusu-Adom
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Patent number: 12065392Abstract: A system for delivering fertilizer to the roots of a plant includes coated fertilizer particles. The coating can include a cellulose derivative, optionally a fatty acid, and a component, such as an aptamer, which binds specifically to a material, such as serine, which is released by the roots of the plant when the plant is actively taking up nutrients from the soil. The permeability of the coating increases when the coated particles are exposed to the material released by the roots of the plant. Thus, nutrient release from the coated fertilizer particles is synchronized with uptake of the nutrients by the plant during active growth. Advantages of the system may include one or more of improved nitrogen use efficiency by the plant, improved crop productivity, and/or reduced leaching of fertilizer from the soil.Type: GrantFiled: September 16, 2019Date of Patent: August 20, 2024Assignees: Carleton University, Her Majesty the Queen in Right of Canada, as represented by The Minister of Agriculture and Agri-Food, The Governors of the University of AlbertaInventors: Juan Schneider, Carlos Monreal, Maria Derosa, Phillip Choi, Emily Mastronardi, Phepafatso Tsae, Francisco Matus
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Patent number: 12065393Abstract: The present invention relates to improvements in known gold containing catalysts. In particular, the present invention relates to improving the stability and/or inhibition of deactivation of gold containing catalysts via the addition of an inorganic oxide, hydroxide, oxo-salt or oxo-acid. There is also disclosed a method for preparing said catalyst most suitably via an impregnation method. Such catalysts are useful in the production of vinyl chloride monomer.Type: GrantFiled: June 19, 2020Date of Patent: August 20, 2024Assignee: JOHNSON MATTHEY PUBLIC LIMITED COMPANYInventors: Nicholas Carthey, Peter Johnston
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Patent number: 12065394Abstract: The present invention provides a compound represented by the following Chemical Formula 1 or a pharmaceutically acceptable salt thereof which can be effectively used for preventing or treating obesity or metabolic syndrome, and a pharmaceutical composition comprising the same. in Chemical Formula 1, R1 and R2 are the same as defined in the specification.Type: GrantFiled: March 26, 2019Date of Patent: August 20, 2024Assignee: Seoul National University R&DBFoundationInventors: Yong Tae Kwon, Srinivasrao Ganipisetti, Ki Woon Sung, Eui Jung Jung, Tae Hyun Bae, Su Ran Mun, Chan Hoon Jung
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Patent number: 12065395Abstract: Disclosed are methods for preparing deuterated analogs of D-serine and compounds useful for preparing deuterated analogs of D-serine.Type: GrantFiled: April 3, 2020Date of Patent: August 20, 2024Assignee: Sun Pharmaceutical Industries, Inc.Inventors: Adam Morgan, Robert S. Lewis
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Patent number: 12065396Abstract: Compounds are provided having the following structure (I) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1a, R1b, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6, R7, R8, L1, L2, G1, G2, G3, a, b, c and d are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.Type: GrantFiled: August 17, 2018Date of Patent: August 20, 2024Assignee: Acuitas Therapeutics, Inc.Inventor: Xinyao Du
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Patent number: 12065397Abstract: Disclosed are benzoate derivatives. Provided is a compound having a formula selected from the group consisting of following structures.Type: GrantFiled: January 13, 2023Date of Patent: August 20, 2024Assignee: ZHEJIANG YUEJIA PHARMACEUTICALS CO., LTDInventor: Jing Zhang
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Patent number: 12065398Abstract: A methanol synthesis plant comprising: a feed pretreating section operable to pretreat a feed stream; a synthesis gas (syngas) generation section comprising one or more reactors operable to produce a syngas synthesis product stream comprising synthesis gas from the feed stream; a methanol synthesis section comprising one or more methanol synthesis reactors operable to produce a synthesis product comprising methanol; and/or a methanol purification section operable to remove at least one component from the synthesis product to provide a purified methanol product; wherein the methanol synthesis plant is configured such that, relative to a conventional methanol synthesis plant, more of the net energy required by the methanol synthesis plant, the feed pretreating section, the syngas generation section, the methanol synthesis section, the methanol purification section, or a combination thereof, is provided by a non-carbon based energy source, a renewable energy source, and/or electricity.Type: GrantFiled: January 14, 2020Date of Patent: August 20, 2024Assignee: SABIC GLOBAL TECHNOLOGIES B.V.Inventors: Joseph William Schroer, Scott Stevenson, Andrew Mark Ward, Tim Abbott, Kenneth Francis Lawson, Michael Edward Huckman, Zhun Zhao, Arno Oprins
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Patent number: 12065399Abstract: The present invention provides new arylsulfonamide compounds having the general formula (I) wherein L, R1, R2, R3 and R4 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.Type: GrantFiled: February 15, 2022Date of Patent: August 20, 2024Assignee: Hoffmann-La Roche Inc.Inventors: Barbara Biemans, Luca Gobbi, Georg Jaeschke, Henner Knust, Lothar Lindemann, Fionn O'Hara, Jean-Marc Plancher
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Patent number: 12065400Abstract: Methods for making higher-octane fuel components from a feed stream of C8+ paraffins, including catalytically cracking the C8+ paraffins using a Zeolite catalyst to produce a reaction product of mid-chain paraffins and olefins and short-chain paraffins and olefins. The reaction product comprises liquid phase paraffins having an increased Octane Value over the feed stream paraffins. The reaction product further comprises a gas phase of short-chain paraffins which are separated from the liquid phase. In embodiments, the short chain olefins are hydrogenated to form mid-chain paraffins and a gas phase containing short-chain paraffins.Type: GrantFiled: April 19, 2022Date of Patent: August 20, 2024Assignee: SWIFT FUELS, LLCInventors: Chris D'Acosta, Jeffery Miller, Robert Hoch
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Patent number: 12065401Abstract: An integrated process for producing para-xylenes may include catalytically reforming a naphtha feed stream; separating the reformate stream into a C1-C7 hydrocarbon stream and a C8+ hydrocarbon stream; exposing the C1-C7 hydrocarbon stream to a first solvent in a solvent extraction unit to form a non-aromatic hydrocarbon stream and an aromatics stream; upgrading the aromatics stream to form a toluene-rich transalkylation feed stream; separating the C8+ hydrocarbon stream into a C9+ hydrocarbon stream, a para-xylene stream and a xylene isomer stream; dealkylating the C9+ hydrocarbon stream; separating the dealkylation product stream into an additional xylene stream and a tri-methyl benzene rich stream; and upgrading the toluene-rich transalkylation feed stream and the tri-methyl benzene rich stream with a hydrogen stream to produce an alkyl-benzene stream and additional xylene stream, wherein a ratio by weight of the toluene-rich transalkylation feed stream to the tri-methylbenzene rich stream is from 0.Type: GrantFiled: March 14, 2023Date of Patent: August 20, 2024Assignee: Saudi Arabian Oil CompanyInventors: Qi Xu, Veera Venkata Ramakrishna Tammana, Mohammed I. Alamer
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Patent number: 12065402Abstract: This disclosure relates to modulators of liver receptor homologue 1 (LRH-1) and methods of managing disease and conditions related thereto. In certain embodiments, modulators are derivatives of hexahydropentalene. In certain embodiments, this disclosure relates to methods of treating or preventing cancer, diabetes, or cardiovascular disease by administering an effective amount of a hexahydropentalene derivative disclosed herein.Type: GrantFiled: May 22, 2023Date of Patent: August 20, 2024Assignee: EMORY UNIVERSITYInventors: Eric Ortlund, Suzanne Mays, Nathan Jui, Autumn Flynn, Michael Dugan
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Patent number: 12065403Abstract: A method for preparing methyl acrylate comprises heating in a reaction zone a mixture comprising acrylic acid, methanol, and an acid catalyst to react and form a reaction product comprising methyl acrylate which is vaporized with other light components and then fed to a distillation zone. A feed stream entering the reaction zone comprises methanol and acrylic acid in a molar ratio of greater than 1 and less than 2, and a residence time in the reaction zone ranges from 0.25 to 2 hours. A distillate from the distillation zone is condensed and phase-separated to form an organic phase comprising methyl acrylate and an aqueous phase. A portion of the organic phase is returned to the distillation zone as organic reflux. The remainder of the organic phase and the aqueous phase of the distillation zone is fed to an extraction column to form a methanol rich aqueous effluent and an organic effluent comprising methyl acrylate.Type: GrantFiled: April 2, 2020Date of Patent: August 20, 2024Assignee: Rohm and Haas CompanyInventors: Reetam Chakrabarti, Minh N. Ngo, James Elder
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Patent number: 12065404Abstract: Disclosed are novel C4-carboxylic acid-substituted tryptamine derivative compounds and pharmaceutical and recreational drug formulations containing the same. The pharmaceutical formulations may be used to treat brain neurological disorders.Type: GrantFiled: August 11, 2022Date of Patent: August 20, 2024Assignee: Enveric Biosciences Canada Inc.Inventors: Jillian M. Hagel, Ye Cai, Kaveh Matinkhoo, David James Press, Glynnis Elizabeth Jensen, Peter J. Facchini
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Patent number: 12065405Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R8, R9, X, Y, Z, W, and m are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient.Type: GrantFiled: April 12, 2023Date of Patent: August 20, 2024Assignee: ATAI Therapeutics, Inc.Inventors: Robert B. Perni, Glenn Short, Srinivas G. Rao, Tanweer A. Khan
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Patent number: 12065406Abstract: The present application relates to a compound represented by Chemical Formula 1, an organic optoelectronic diode and a display device.Type: GrantFiled: January 30, 2020Date of Patent: August 20, 2024Assignee: LT MATERIALS CO., LTD.Inventors: Jin-Hwan Shin, Yong-Woo Kim, Gwang-Il Dong
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Patent number: 12065407Abstract: Provided are novel compounds of Formulas (I) and (II), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful as dual FKBP12/FKABP inhibitors. Also provided are pharmaceutical compositions comprising the novel compounds of Formulas (I) and (II) and their use in treating Parkinson's disease.Type: GrantFiled: August 21, 2018Date of Patent: August 20, 2024Assignee: PLEX PHARMACEUTICALS, INC.Inventors: Surya Kanta De, Sridhar G. Prasad, Marshall C. Peterman
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Patent number: 12065408Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).Type: GrantFiled: November 3, 2023Date of Patent: August 20, 2024Assignees: VIRGINIA COMMONWEALTH UNIVERISTY, KING ABDULAZIZ UNIVERSITY, CHILDREN'S HOSPITAL OF PHILADELPHIA (CHOP), ILLEXCOR HOLDINGS, LLCInventors: Martin Safo, Yan Zhang, Andrew Fleischman, David Light, Moustafa El-Araby, Abdelsattar Omar, Osheiza Abdulmalik
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Patent number: 12065409Abstract: Provided herein are compounds useful in treating exposure to an organophosphorus compound, such as a nerve agent, pesticide, or, generally, an acetylcholinesterase inhibitor, such as sarin. Compositions, e.g. pharmaceutical compositions or dosage forms, comprising the compounds also are provided herein. Methods of treating a patient exposed to a nerve agent, pesticide, or, generally, an acetylcholinesterase inhibitor, e.g., an organophosphorus compound, such as sarin, also are provided.Type: GrantFiled: May 30, 2019Date of Patent: August 20, 2024Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Kazunori Koide, Kiflai Bein, George D. Leikauf, Robert Kruger Bressin, James Proviano Burrows, Adriana Gambino, Dianne Pham
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Patent number: 12065410Abstract: The invention provides polymorphs of a compound of Formula (X): The invention also provided pharmaceutical compositions containing polymorphs of the compound and methods treating conditions in a subject by providing polymorphs of the compound.Type: GrantFiled: June 21, 2023Date of Patent: August 20, 2024Assignee: IMBRIA PHARMACEUTICALS, INC.Inventors: Neil Buckley, Dan Belmont, Sarah Bethune, Krista Diaz
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Patent number: 12065411Abstract: An methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate compound, its synthesis, and its use as an antimicrobial agent.Type: GrantFiled: January 31, 2024Date of Patent: August 20, 2024Assignee: KING FAISAL UNIVERSITYInventors: Mai Mostafa Khalaf Ali, Hany Mohamed Abd El-Lateef Ahmed, Antar Ahmed Abdelhamid Ahmed, Amer A. Amer
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Patent number: 12065412Abstract: Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.Type: GrantFiled: May 11, 2023Date of Patent: August 20, 2024Assignee: The Regents of the University of CaliforniaInventors: Alan S. Verkman, Marc H. Levin, Onur Cil, Sujin Lee
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Patent number: 12065413Abstract: Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.Type: GrantFiled: May 26, 2021Date of Patent: August 20, 2024Assignee: THE JOHNS HOPKINS UNIVERSTYInventors: Martin G. Pomper, Ronnie C. Mease, Ying Chen, Sangeeta Ray
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Patent number: 12065414Abstract: The invention relates to process for the preparation of isoxazoline-substituted benzamide compound and intermediates thereof. The invention also relates to process for the preparation of Fluralaner and intermediates thereof.Type: GrantFiled: September 2, 2021Date of Patent: August 20, 2024Assignee: ZYDUS LIFESCIENCES LIMITEDInventors: Kumar Kamlesh Singh, Sanjay Jagdish Desai, Kuldeep Natwarlal Jain, Jitesh Amratlal Desai, Sarvil Dhirajbhai Patel
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Patent number: 12065415Abstract: A process for manufacturing a polybenzoxazine monomer, crosslinking the latter, and using the crosslinked product to form an ablative thermal protection system for a thruster nozzle or atmospheric reentry body.Type: GrantFiled: March 10, 2020Date of Patent: August 20, 2024Assignees: ARIANEGROUP SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Romain Tavernier, Lérys Granado, Ghislain David, Sylvain Caillol, Gabriel Foyer
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Patent number: 12065416Abstract: Disclosed are novel compounds of Formula I that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.Type: GrantFiled: January 23, 2023Date of Patent: August 20, 2024Assignees: IMMUNESENSOR THERAPEUTICS, INC., THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Boyu Zhong, Lijun Sun, Heping Shi, Jing Li, Chuo Chen, Zhijian Chen
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Patent number: 12065417Abstract: Selective hydrogenation processes are disclosed that can upgrade impure feeds, such as those obtained from biomass and containing a number of small (e.g., 2-6 carbon atom) molecules having aldehyde and/or ketone carbon atoms. For example, whereas glycolaldehyde and its methylated derivative, hydroxyacetone (acetol) are both high value intermediates for certain downstream processing reactions, they are normally recovered in a condensate from pyrolysis of carbohydrates (e.g., aldose-containing sugars) together with glyoxal and its methylated derivative, pyruvaldehyde. The selective hydrogenation of these compounds bearing two carbonyl carbon atoms, without over-hydrogenation to ethylene glycol and propylene glycol, can increase the concentration of the desired intermediates. These beneficial effects of selective hydrogenation may be achieved through the use of a hydrogenation catalyst comprising noble metals such as Ru and Pt.Type: GrantFiled: January 9, 2020Date of Patent: August 20, 2024Assignee: ARCHER-DANIELS-MIDLAND COMPANYInventors: James Brazdil, Chi-Cheng Ma
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Patent number: 12065418Abstract: Processes and reactor systems for biomass conversion are described. A continuous process for the conversion of carbohydrate-containing feed material into furanic compounds comprises a reaction step comprising subjecting said feed material to reaction conditions in a reaction medium comprising two immiscible liquid phases, including a reactive phase and an extractive phase, and a Brønsted acid as catalyst, wherein the reaction medium comprises a solid component comprising at least a part of a carbohydrate-containing fraction of said feed material.Type: GrantFiled: July 26, 2021Date of Patent: August 20, 2024Assignee: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNOInventors: Paul Mathijs Könst, Johan Urbanus
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Patent number: 12065419Abstract: A novel organic compound is provided. Alternatively, an organic compound that exhibits light emission with favorable chromaticity is provided. Alternatively, an organic compound that exhibits blue light emission with favorable chromaticity is provided. Alternatively, a light-emitting device with favorable emission efficiency is provided. Alternatively, an organic compound having a high carrier-transport property is provided. Alternatively, an organic compound with favorable reliability is provided. An organic compound having at least one amino group in which any one of a substituted or unsubstituted dibenzofuranyl group, a substituted or unsubstituted dibenzothiophenyl group, and a substituted or unsubstituted carbazolyl group is bonded to any one of a substituted or unsubstituted naphthobisbenzofuran skeleton, a substituted or unsubstituted naphthobisbenzothiophene skeleton, and a substituted or unsubstituted naphthobenzothienobenzofuran skeleton is provided.Type: GrantFiled: April 30, 2019Date of Patent: August 20, 2024Assignee: Semiconductor Energy Laboratory Co., Ltd.Inventors: Kyoko Takeda, Hiroshi Kadoma, Yusuke Takita, Tsunenori Suzuki, Satoshi Seo
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Patent number: 12065420Abstract: Disclosed herein are compositions containing an isolated bioactive compound of Formula (X): including less than about 2 wt % of halifordin. Also disclosed are methods for obtaining and using compositions containing the isolated bioactive compound.Type: GrantFiled: August 28, 2019Date of Patent: August 20, 2024Assignee: HARDIE HEALTH LIMITEDInventors: Peter Thomas Northcote, Ameet Jonathan Singh