Abstract: A handle assembly is disclosed for firmly holding a surgical tool. The handle assembly comprises a handle and a locking mechanism attached to the handle. The locking mechanism includes a locking ring, a collet, and a compressible locking pin engageable with the locking ring and collet. The locking ring is moveable between first and second positions relative to the handle. The first position is an unlocked position whereby the locking pin is in a decompressed state relative to the locking ring and the collet. In the first position, a surgical tool may be inserted and withdrawn from the collet of the locking mechanism. The second position is a locked position whereby the locking pin is in a compressed state relative to the locking ring and the collet. In the second position, a surgical tool is anchored in the collet of the locking mechanism.

Abstract: An apparatus, system, and method are disclosed for remediating a condition present in a patient. In some implementations, the apparatus may include a body. Also, the apparatus may include a bone attachment feature. Furthermore, the apparatus may include a first resection feature configured to guide a first osteotomy of a donor bone. In addition, the apparatus may include a second resection feature configured to guide a second osteotomy of the donor bone, the second osteotomy offset from the first resection feature by a dimension that satisfies a predefined bone graft dimension.

Abstract: An orthopedic guide may include a cannulated shaft, a body and a plurality of arms. The body can be coupled to the cannulated shaft. The plurality of arms can extend radially outward from the body. One or more of the plurality of arms can include an outer radial end portion that has a length in a radial dimension configured to indicate a minimum safety boundary for a humeral implant relative to a cortex of a humerus.

Abstract: An example method includes determining, by control circuitry, a flow rate of a fluid within a catheter lumen fluidically coupled to a valve, comparing, by the control circuitry, the flow rate to a flow rate reference value, and determining, by the control circuitry, a duty cycle of a first operational state and a second operational state of the valve based on a difference between the flow rate and the flow rate reference value. The method also includes controlling, by the control circuitry, the valve to be in the first and second operational states to control a suction force applied to the catheter lumen according to the duty cycle.

Abstract: An example method includes determining, by control circuitry, a flow rate of a fluid within a catheter lumen fluidically coupled to a valve, and comparing, by the control circuitry, the flow rate to a first flow rate threshold and a second flow rate threshold less than the first flow rate threshold. In response to determining that the flow rate is greater than or equal to the first flow rate threshold, the example method includes controlling, by the control circuitry, the valve to be in a first operational state, and in response to determining that the flow rate is less than or equal to the second flow rate threshold, controlling, by the control circuitry, the valve to be in a second operational state.

Abstract: An aspiration catheter including a body having a proximal end and an opposite distal tip with a lumen extending in a longitudinal direction therethrough from the proximal end to the distal tip. The aspiration catheter further includes a stabilizing structural member stabilizing the body relative to the inner wall of the vessel to minimize movement and/or radial expansion of the distal tip of the body while subject to aspiration that otherwise may potentially damage the inner wall of the vessel.

Abstract: Cyclic aspiration system producing a cyclic aspiration pressure waveform of intermittent cyclic intervals of vacuum pressure below atmospheric pressure and a positive pressure higher than the vacuum pressure. The system including an aspiration catheter, a vacuum pump, and connected in fluid communication therebetween a positive pressure pulse generator mechanism including at least one displaceable member displaceable within a housing, wherein the at least one displaceable member controls passage therethrough the housing of the vacuum pressure and produces the positive pressure pulse by compressing collectable fluid therein. The system further including at least one actuator arranged externally of the housing displacing the at least one displaceable member within the housing.

Abstract: Cyclic aspiration system producing a cyclic aspiration pressure waveform of intermittent cycles of vacuum pressure below atmospheric pressure and positive pressure higher than vacuum pressure. The system includes a dual pressure generator receptacle disposed proximally of and connected in fluid communication with an aspiration catheter. The dual pressure generator receptacle receiving a collectable fluid therein that is intermittently cyclically subjectable to application or withdraw of a compressible force via a linear displacement mechanism. Positive pressure is generated while the collectable fluid in the dual pressure generator receptacle is subject to the compressive force and vacuum pressure is generated when not subject to the compressive force. The cyclic aspiration pressure waveform is produced via the dual pressure generator receptacle without a separate vacuum pump.

Abstract: Cyclic aspiration system producing an associated cyclic pressurized waveform of intermittent cyclic intervals of vacuum pressure below atmospheric pressure and a positive pressure higher than the vacuum pressure. The system including a vacuum pump generating vacuum pressure, a conduit connected in fluid communication to the vacuum pump, and an aspiration catheter connected in fluid communication to the conduit. Associated with the conduit is a positive pressure pulse generator mechanism that controls via a vacuum pressure gating device passage therethrough the conduit of the vacuum pressure generated by the vacuum pump and intermittently cyclically produces a positive pressure pulse.

Abstract: An aspiration vacuum source comprises a vessel having a positive pressure fluid chamber and a vacuum chamber. The vacuum source having a primary tubing, and the positive pressure fluid chamber connected in fluid communication with the primary tubing via an auxiliary tubing. A fluid piston is slidably received within the positive pressure fluid chamber. A vacuum piston is slidably received within the vacuum chamber and produces a vacuum within the vacuum chamber upon movement of the vacuum piston. The fluid piston and the vacuum piston are each fixedly attached to be movable together within the positive pressure fluid chamber and the vacuum chamber, respectively. A secondary tubing is connected in fluid communication to the vacuum chamber. A manual pump is connected in fluid communication with the primary tubing. A vacuum is producible in the vacuum chamber in response to repeated manipulation of the manual pump.

Abstract: A guidewire insertion device (10) includes a first guidewire (12) including an electromagnetic tip (14); a second guidewire (16) including a magnetic tip (18); and a controller (33) configured to modulate a force of the electromagnetic tip of the first guidewire to control movement of the magnetic tip of the second guidewire.

Abstract: Disclosed are various embodiments and related methods of an aspiration catheter configured for removal of an occlusion from a vessel of a patient. The aspiration catheter (2200) can include an elongated body (2110) with a reinforcement element (2241) extending along a first length of the elongated body. In some embodiments, the aspiration catheter can include one or more of a deformer (2230), such as a movable deformer, a shaped distal end, and an occlusion grasper for efficiently and effectively securing and removing the occlusion to allow blood flow to be restored.

Abstract: A catheter is disclosed for treating aneurysms. The catheter can include a liner having a proximal end, a distal end, an outer surface, and an internal lumen extending from the proximal end to the distal end along a longitudinal axis A. A braid is disposed on the outer surface of the liner and extends from the proximal end to the distal end of the liner. The braid comprises a plurality of wires wherein a first portion of the wires are made from tungsten and a second portion of the wires are made from a different material. A first distal section of the braid has a pic rate of about 330 picks per inch (“ppi”). A jacket is disposed about the braid and extends from the proximal end to the distal end.

Abstract: A method of treating a calculi mass can include using an ultrasonic probe to produce acoustic energy and fragment the mass. The method can include varying the frequency at which fragmentation occurs to treat the mass with a resonant frequency. The ultrasonic probe can have a distal tip for contact with the mass, where the tip has a morphology for concentrating stress on the mass. The ultrasonic probe can have two or more ultrasonic horns to allow for higher voltage and power levels.

Abstract: Cyclic aspiration system including an aspiration catheter and a cyclic aspiration source connected in fluid communication thereto, wherein the cyclic aspiration pressure source produces a cyclic aspiration pressure waveform of intermittently cycling intervals of a vacuum pressure below atmospheric pressure and a positive pressure higher than the vacuum pressure. The system further including a non-powered internal structural impediment disposed within the lumen of the aspiration catheter and configured to engage with a clot capturable therein during resulting movement between the clot and the non-powered internal structural impediment while subject to the cyclic aspiration pressure waveform to assist in capture of the clot. The non-powered internal structural impediment may be permanently attached to the aspiration catheter or a separate component or device independently slidable within the lumen of the aspiration catheter.

Abstract: A pulsatile aspiration system is herein disclosed that includes a catheter and pump system. The catheter includes an outer wall, a proximal section, a distal section, and an internal wall dividing the proximal section into a central main lumen and an auxiliary lumen. The pump system is in fluid communication with the catheter and independently controls the negative fluid pressure and the positive fluid pressure in the central main lumen and the auxiliary lumen so as to produce at the distal end of the catheter a pulsatile aspiration waveform variable between a maximum aspiration pressure and a maximum positive pressure. The maximum aspiration pressure is producible at the distal end of the catheter when the resulting pressure is exclusively negative fluid pressure, and the maximum positive pressure is producible at the distal end of the catheter when the positive fluid pressure counterbalances that of the negative fluid pressure.

Abstract: A medical instrument for insertion into and removal of kidney stone fragments from a urinary tract of a patient body includes a flexible elongate shaft coupled with a fragment retaining mechanism. The retaining mechanism can be configured to retain a plurality of fragments so that the plurality of fragments is removed from the patient with a single insertion/extraction cycle of the instrument. A fragment gathering mechanism urges fragments toward the retaining mechanism. In use, the instrument can be inserted through a working channel of a ureteroscope.

Abstract: A tissue retrieval system can include a tissue retrieval bag with an elongate profile. The tissue retrieval bag can have a relatively large volume, but be rollable to a stowed configuration to fit in a relatively small diameter introducer. The tissue retrieval system can include one or more support arms coupled to the tissue retrieval bag, the support arms biased to position the tissue retrieval bag in an access position once deployed from the introducer. A tissue retrieval system can have a hybrid tissue retrieval bag including material properties that vary along the depth of the bag from an open end to a closed end. A tissue retrieval bag can be used in conjunction with an introducer, or as a stand alone tissue retrieval bag.

Abstract: Methods and apparatus for evaluating and manipulating objects in a body, for example emboli in a body lumen are described, and in some examples methods and apparatus use adaptable tips on catheters, for example aspiration catheters, for manipulating and/or removing such emboli.

Abstract: Surgical equipment includes a pipe section to be inserted into an organism, a handle section extending in a direction nonparallel to a longitudinal direction of the pipe section, a transitioning section that couples a rear end portion of the pipe section and a front end portion of the handle section, and a treatment instrument disposed at a front end portion of the pipe section. The surgical equipment includes a manipulator section disposed in the handle section and manipulated when causing the treatment instrument to operate and a transmission member that connects the treatment instrument and the manipulator section and transmits a motion of the manipulator section to the treatment instrument. The transmission member includes a wire. The transitioning section has a hollow pipe shape through which the wire can be inserted. Only the wire is inserted through the transitioning section.

Abstract: A forceps system is disclosed, including a handle and a shaft-and-jaw assembly. The handle includes an immovable proximal handgrip and a lever resiliently pivotably coupled to the immovable proximal handgrip, such that exertion of a manual gripping force on the lever pivots the lever in a proximal direction toward the handgrip. The shaft-and-jaw assembly is releasably couplable to the handle, the shaft-and-jaw assembly including at least one pivotable jaw member normally biased to an open configuration, the open configuration of the jaws corresponding to a released configuration of the handle, the jaws being moved to a closed configuration upon the exertion of the manual gripping force on the lever, pivoting the lever toward the handgrip.

Abstract: A surgical instrument includes an articulated end-effector including a support structure, first and second tips having a respective elongated body including a proximal attachment root and a distal free end. The first and second roots are axially adjacent and globally interposed with the support structure. The support structure, and first and second tips are mutually articulated in a common rotation axis defining an axial direction coincident/parallel to the common rotation axis, defining a relative degree of freedom of opening/closing between the first and second tips. The first tip body includes a blade portion with a cutting edge rotating with the first free end. The second tip includes a counter-blade portion rotating with the second free end. The counter-blade portion abuts the cutting edge, elastically axially bending the blade portion. The first and second roots each directly and intimately contact the support structure.

Abstract: There is provided a resection device to remove a portion of a solid organ of a patient in the context of resection surgeries. The resection device includes a magnet assembly implantable into a body cavity of the patient, the magnet assembly including a plurality of magnet elements flexibly connected in series. The magnet assembly is configured to be positioned around a portion of an outer surface of the solid organ to magnetically attract opposite magnet elements together to compress opposite sides of the solid organ along a resection line therebetween to separate the solid organ in a resectioned portion and a remaining portion. The magnet elements can be received in a housing and have various shapes. The resection device can include additional features such as a leading elongated member that can aid in the positioning of the resection device, and a trailing elongated member.

Abstract: An embodiment includes an apparatus for carpel tunnel syndrome surgery. The apparatus comprises: a shaft including a shaft proximal end, a shaft distal end, and a shaft long axis, wherein the shaft distal end comprises a raised edge; a linkage included within the shaft; a blade coupled to a distal end of the linkage; wherein (a)(i) an axis parallel to the shaft long axis intersects the raised edge but does not intersect the shaft, (a)(ii) the raised edge is curvilinear, (a)(iii) the raised edge includes a first lateral edge portion, a second lateral edge portion, and a middle edge portion between the first and second lateral edge portions; and (a)(iv) the first and second lateral edge portions are both proximal to the middle edge portion. Other embodiments are described herein.

Abstract: A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either within the brain. Once positioned at a desired location, the obturator is removed, leaving a distal end of the outer sheath adjacent an area of interest, and creating a working corridor. Interrogation of the area of interest may be performed to evaluate a disorder and/or abnormality, as well as evaluate treatment regimes. Interventional devices may also be introduced to the area of interest, as well as a variety of treatments.

Abstract: A surgical access device, such as a trocar, for use in providing access to a patient in a surgical setting is disclosed. The surgical access device includes an irradiation component to inactivate and sterilize gas that accidentally escapes a pneumoperitoneum, or ambient gas from outside the patient that may become entrained into the pneumoperitoneum. The surgical access device may include a central lumen that is gasketless or implements a gasket. The irradiation source may include an ultraviolet radiation source on or in the body of the surgical access device, and may be part of a discrete, removable attachment to a main part of the surgical access device body.

Abstract: An intraosseous access system includes a driver, a needle, and an obturator positioned in the needle to prevent entry of bodily tissues into the lumen. The driver includes control logic configured to modify operation of the driver upon an indication that a change in modality is detected. The obturator includes a sensor such as an electrical impedance sensor. The electrical impedance sensor can include a passive RFID chip configured to activate when the change in modality is detected.

Abstract: According to some embodiments, systems and methods are provided for non-invasively detecting the force generated by a non-invasively adjustable implantable medical device and/or a change in dimension of a non-invasively adjustable implantable medical device. Some of the systems include a non-invasively adjustable implant, which includes a driven magnet, and an external adjustment device, which includes one or more driving magnets and one or more Hall effect sensors. The Hall effect sensors of the external adjustment device are configured to detect changes in the magnetic field between the driven magnet of the non-invasively adjustable implant and the driving magnet(s) of the external adjustment device. Changes in the magnetic fields may be used to calculate the force generated by and/or a change in dimension of the non-invasively adjustable implantable medical device.

Abstract: An implantable growing rod assembly adapted to be secured along a length of a spine for treating deformities of the spine. The assembly includes a housing, a fixed rod extending along a longitudinal axis away from the housing, and an expansion rod extendible from the housing along the longitudinal axis. A driver assembly is fixed to the housing and adapted to translate the expansion rod along the longitudinal axis.

Abstract: The present invention provides methods of forming flexible implant devices and U-bridge implants that drive into curved trajectories to enhance implant fixation in bone. The curved drilling trajectories avoid regions of low bone mineral density, such that flexible implants and/or U-bridge implants driven into the curved drilling trajectories are anchored in regions of high bone mineral density to improve the stability of bone fixation. The flexible implants and U-bridge implants are suitable for several applications, including but not limited to spinal fixation, orthopedic bone fixation, and neurosurgery.

Abstract: A fixation system includes a rod, a fastener with a spherical head, a tulip housing and a cap within the tulip housing. The housing includes a pair of arms that define a rod channel, and each arm defines an upper locking opening and a lower locking opening, all of which open to the interior of the housing. The cap includes a main body defining a spherical cavity for receiving the spherical head of the fastener, and a plurality of legs that can flex to receive the spherical head and to clamp the spherical head within ta conical bore of the tulip housing. The cap includes a pair of wings with locking tabs, each locking tab configured to engage a corresponding upper and lower locking opening. When the tabs are engaged in the upper locking openings, the cap is in an unlocked state in which the spherical head of the fastener can be introduced into the spherical cavity of the cap from the bottom of the tulip housing.

Abstract: A polyaxial bone anchoring device includes a bone anchoring element having a head, a receiving part having a channel for receiving a rod and an accommodation space for pivotably holding the head, and a pressure member having a pressure exerting surface and a deformable portion with a free end. The deformable portion is adjustable from a first configuration where a first part of the deformable portion is supported at a first axial position relative to the receiving part while a second part of the deformable portion protrudes further radially into the channel than parts of the deformable portion positioned axially above the second part, to a second configuration where the second part of the deformable portion is deformed radially outwardly and the pressure exerting surface is shifted lower axially to exert pressure on the head while the first part of the deformable portion remains supported at the first axial position.

Abstract: A polyaxial bone anchoring device includes: an anchoring element having a shaft for anchoring in a bone and a head, the head having a spherically-shaped outer surface portion; a receiving part configured to be pivotably connected to the head, the receiving part having a top end and a bottom end, a longitudinal axis extending through the top end and the bottom end, a channel transverse to the longitudinal axis for receiving a rod, and an accommodation space for accommodating the head, the accommodation space having a lower opening at the bottom end, a sleeve-like insert piece configured to be positioned around a portion of the head and to pivot in the receiving part, the insert piece having a spherically-shaped outer surface portion, wherein a lower edge of the insert piece extends past the lower opening in a direction away from the receiving part when the insert piece is seated in the receiving part in a position in which a central axis of the insert piece is coaxial with the longitudinal axis, and wherein th

Abstract: A bone anchoring device includes a receiving part having a central axis, two legs defining a recess for receiving a rod, and a head receiving portion that is at least partially expandable and having an opening for inserting and pivotably holding a head of a bone anchoring element therein, and a locking ring mountable around the head receiving portion in an axial direction while a rotational orientation of the locking ring relative to the receiving part remains constant. When the locking ring is around the head receiving portion, the locking ring is rotatable around the central axis from a first rotational orientation to a second rotational orientation where a compressive force exerted by the locking ring on the head receiving portion is greater than at the first rotational orientation.

Abstract: A polyaxial bone anchoring device includes a receiving part with two legs defining a recess for receiving a rod and a pressure member for exerting pressure on a head of a bone anchoring element in the receiving part, the pressure member having an engagement portion. The engagement portion can extend at least partially into a leg and is directly engageable from outside the bone anchoring device to move the engagement portion axially for adjusting the pressure member from a non-locking position where the head is pivotable to a locking position where the head is clamped. When the pressure member is in the locking position and the engagement portion is free from any outside axial forces, a first contact surface of the receiving part cooperates with a second contact surface of the pressure member to hold the pressure member in the locking position.

Abstract: An interspinous spacer includes an actuator screw having a proximal end and a shaped cavity in the proximal end, where the shaped cavity is configured for receiving a bit of a driver tool having a complementary shape for rotating the actuator screw using the driver tool; a wedge coupled to the actuator screw, wherein, as the actuator screw is rotated using the driver tool, the actuator screw and the wedge move longitudinally relative to the body; and a first arm and a second arm, wherein the first and second arms are rotatably coupled to the distal portion of the body and configured for rotating in response to longitudinal movement of the wedge. The interspinous spacer may include locking inserts or a locking ring to resist rotation of the actuator screw absent the driver tool.

Abstract: A system for securing a spinal rod to a bone structure using a connector is provided. The connector functions by modulating friction on a band in two band channels and locking the spinal rod in a separate rod channel. An instrument is also provided for tensioning the band.

Abstract: An insertion device for deploying an implant includes an elongated main body having a distal locking portion for coupling to the implant and a proximal handle portion. The main body defines a central passage and the distal locking portion has outer ridges and slots to allow the outer ridges to flex radially inward when mounting to the implant. A plunger slides in the central passage for movement between an unlocked position for mounting the implant on the distal locking portion, a locked position for locking the implant on the distal locking portion, and an insertion instrument deployed position for deploying the actuation plunger to move the blades from the stowed position to the deployed position. A spike cap drive rotatably mounts on the main body having a socket end for engaging a drive nut on the implant to, in turn, move the spike cap.

Abstract: Various implementations include an adjustable implant such as a distraction/compression device. In certain cases, the adjustable implant can include a housing; an adjustable member at least partially positioned within the housing and configured to translate relative to the housing; and an intermediary member positioned between the housing and the adjustable member.

Abstract: A bone plate includes first and second ends opposed along a longitudinal axis oriented along a longitudinal direction, first and second sides opposed along a lateral direction, and a bone-facing surface and an outer surface opposed along a transverse direction. The plate defines a first hole and a second hole arrangement extending from the outer to the bone-facing surface. The second hole arrangement is distal of the first hole, which is configured to receive a first fixation member, and the second hole arrangement is configured to receive at least one second fixation member for affixing with underlying bone. The plate is pivotable along an angulation range about the first hole. The second hole arrangement laterally crosses the longitudinal axis, defines the angulation range, and allows the at least one second fixation member to substantially secure the plate to the underlying bone at any angulation within the angulation range.

Abstract: An intra-osseous support structure can be used to fixate opposed portions of bone. In some examples, the intra-osseous support structure is positioned in openings formed in adjacent portions of bones. Fasteners are inserted through the bone portions to secure the intra-osseous support structure in the bones. Depending on the application, one or more external bone plates may also be applied to the bone portions. The external bone plate may be in compression while the intra-osseous support structure is in tension under load in situ.

Abstract: A method and apparatus for maintaining a position of a first bone part relative to a second bone part. The method includes the steps of: a) obtaining an apparatus having a base in the form of a plate and at least one elongate wire component having at least a portion with a length projecting angularly away from the base; b) placing the apparatus in an operative position wherein at least a portion of the length of the at least one elongate wire component engages the first bone part and a portion of the base at least one of: i) bears against; and ii) is adjacent to the second bone part; and c) with the apparatus in the operative position, anchoring the base to the second bone part to fix the apparatus in the operative position. At least a part of the base and at least a part of the at least one elongate wire component are made from metal and permanently connected.

Abstract: A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a threaded outer sleeve that rotates relative to the outer shaft until locked down. Independent rotation of the threaded outer sleeve relative to the threaded distal tip allows compression or distraction to modify the gap between the vertebral bodies. The screws are passed from the inferior to superior vertebra or superior to inferior, for example, through a trans-pedicular route to avoid neurological compromise. At the same time, the path of screw insertion is oriented to reach superior or inferior vertebra. An intervertebral cage of the system is configured for lateral expansion from a nearly straight configuration to form a large footprint in the disc space. The screws and cage may be combined for improved fixation with minimal invasiveness.

Abstract: Systems and methods for electroporation catheters are provided herein. An electroporation catheter includes a shaft, and a variable diameter loop coupled to a distal end of the shaft, the variable diameter loop including a plurality of electrodes. The catheter further includes a plurality of electrical wires connected to the plurality of electrodes and extending through the variable diameter loop and the shaft, the plurality of electrical wires configured to energize the plurality of electrodes, and a multi-lumen arrangement extending through at least a portion of at least one of the shaft and the variable diameter loop. The multi-lumen arrangement includes a first lumen housing a first subset of the plurality of electrical wires, and a second lumen housing a second subset of the plurality of electrical wires.

Abstract: The invention relates to a method of reducing volume of a tissue without damaging epithelial tissue, the method comprising inserting an IRE device within a zone of a mouth or a nose, enclosing an area of interest of said tissue within a space between at least two electrodes; and applying irreversible electroporation ablation treatment.

Abstract: Provided in the present disclosure are materials, devices, systems, and methods for performing cryo-surgery in a mammalian subject. More particularly, presented are a slurry, devices, systems, and methods for subcutaneously injecting the slurry into a patient in need of bodyfat reduction intervention. The slurry, devices, systems, and methods permit highly efficacious subcutaneous ice phase-change lipolysis while not requiring that the patient be placed under general anesthesia, nor requiring significant new surgical training among practitioners.

Abstract: The present disclosure provides apparatuses and methods for treating conditions such as chronic daily headache, cluster headache, tension headache, migraine, or acute headache of a patient. In example methods, a cryotherapy element is introduced into the nasal cavity or pterygopalatine fossa to cool or cryoablate at least one of a nasal nerve tissue or nasal blood vessel. The cryotherapy element may be introduced into the nasal cavity in a collapsed position, and prior to cooling a target treatment site may be expanded to an expanded configuration.

Abstract: The recovery of an intact volume of tissue proceeds with a delivery cannula distal end positioned in confronting adjacency with the volume of tissue to be recovered. A tissue cutting and capture assembly formed of a plurality of metal leafs is deployed from the distal end of the delivery cannula. The tips of these leafs carry a pursing cable assembly, which is electrically excited to electrosurgically cut around and circumscribe the tissue volume. These pursing cables are tensioned to complete the envelopment of the tissue volumes by drawing the leaf tips together. An essential attribute of the disclosed apparatus is the confinement of the path of electrical conduction of constant current required to achieve tissue cutting to only those portions of the deploying and retracting resistively heated portion of the electrically conductive cutting and pursing cable that are in direct contact with tissue.

Abstract: Devices, systems and methods are provided for subdermal tissue tightening through soft tissue coagulation and for use in cosmetic surgery applications. The devices, systems and methods of the present disclosure may be used for a minimally invasive application of helium-based cold plasma energy to subcutaneous tissue for the purpose of tightening lax tissue.

Abstract: A high-voltage generating circuit for a catheter and an ablation tool. The high-voltage generating circuit comprises: N voltage conversion units (111a, 121a, 131a, 141a), N energy storage units (112a, 122a, 132a, 142a), a voltage adjustment unit (200a), and a control unit (300a).