Patents Issued in August 29, 2024
-
Publication number: 20240286962Abstract: A method for producing carbonized or graphitized molding parts is particularly simple to implement and also allows producing complex molding parts without mechanical post-processing. This is achieved by the production of a pourable liquid polymer mixture which is as homogenized as possible, consisting of a carbon granulate, pitch, soot or graphite powder and polyacrylnitrile dissolved in a solvent, filling the liquid polymer mixture into a casting mold and immersing the filled casting mold in water over a predetermined period of time until the polymer mixture is sufficiently cured and dimensionally stable, and subsequent breaking of the casting mold and stabilizing the prefabricated cured molding part by uniform heating up in a furnace in air at a predefined temperature for stabilizing and degassing volatile constituents, and performing a high-temperature treatment for carbonizing or graphitizing the molding part in a furnace under protective gas.Type: ApplicationFiled: June 29, 2022Publication date: August 29, 2024Applicant: Nippon Kornmeyer Carbon Group GmbHInventors: Torsten KORNMEYER, David KLEIN
-
Publication number: 20240286963Abstract: A method for coating at least one fibre with a boron nitride interphase, includes treating the at least one fibre with a treatment medium containing ammonia borane and having a temperature of 100° C. or higher and a pressure of 1 bar or higher.Type: ApplicationFiled: June 13, 2022Publication date: August 29, 2024Inventors: Adrien DELCAMP, Cyril AYMONIER, Nicolas BISCAY
-
Publication number: 20240286964Abstract: A ceramic matrix composite (CMC) component and method of forming the CMC component with multiple layers of impregnated matrix fibers, at least one of the multiple layers including at least one CMC prepreg formed from a plurality of twisted tows, twisted through at least one turn/meter.Type: ApplicationFiled: February 27, 2023Publication date: August 29, 2024Inventors: MIchael Schuster, Daniel Gene Dunn
-
Publication number: 20240286965Abstract: A method of preparation of a construction element by carbonation, includes a) preparing a composition containing a cement, water and chemical additives; b) pre-drying the composition; then c) placing the pre-dried composition in a chamber of an incubator, the chamber containing at least one inlet and one outlet, the pre-dried composition being carbonated, in a carbonation procedure, by feeding into the chamber, through the inlet, a flow of CO2 containing gas, variations of the CO2 concentration in the chamber being kept below 10% of a reference value during the whole carbonation procedure, during the carbonation procedure, the pressure within the chamber being atmospheric pressure, the relative humidity within the chamber being above 80° % and the temperature within the chamber ranging from 20° C. to 80° C. The chemical additives in the composition include more than 0.05% in weight, compared to the total weight of the cement, of a cement hydration retarder.Type: ApplicationFiled: June 22, 2022Publication date: August 29, 2024Inventors: Bruno HUET, Vincent BRIAUD, Vincent MEYER, Guillaume LOUBET, Christophe LEVY
-
Publication number: 20240286966Abstract: The application is directed to products and methods related to a TiB2 substrate with a directing feature, wherein the directing feature is configured to direct TiB2 wettable material in a predetermined direction. In some embodiments, the TiB2 substrate is at least partially covered with solid aluminum metal.Type: ApplicationFiled: May 7, 2024Publication date: August 29, 2024Inventors: Xinghua Liu, Benjamin D. Mosser
-
Publication number: 20240286967Abstract: The present disclosure relates generally to carbon-based products. More particularly, the present disclosure relates to acid-impregnated carbon-based products having at least one nitrogen-containing compound covalently bound to a porous carbon matrix, methods of making same, and uses of same in industry and agriculture.Type: ApplicationFiled: February 28, 2024Publication date: August 29, 2024Inventors: Mitchel Flegel, Cristine Selirio, Prem Pokharel, Mark Howell, Robert Mackie
-
Publication number: 20240286968Abstract: A liquid fertilizer additive solution composition and methods of making thereof.Type: ApplicationFiled: April 25, 2024Publication date: August 29, 2024Inventors: Gary David McKnight, David Bruce Parker, Yang Zehni, Ray Perkins, Wei Xu
-
Publication number: 20240286969Abstract: A fertiliser pellet comprising: a first region of a nitrogen-providing fertiliser composition; and a second region adhered to the exterior of the first region, the second region comprising a fertiliser composition capable of providing (a) two or more alkali metal and/or alkaline earth metal nutrients and (b) sulphur.Type: ApplicationFiled: May 9, 2024Publication date: August 29, 2024Inventors: Robert John Meakin, Timothy David Lewis
-
Publication number: 20240286970Abstract: Compositions and methods of making a liquid fertilizer additive of biodegradable polymeric and/or oligomeric nitrification inhibitors.Type: ApplicationFiled: April 22, 2024Publication date: August 29, 2024Inventors: Gary David McKnight, Randall Linwood Rayborn
-
Publication number: 20240286971Abstract: A rosin-based sustainable dust and moisture control coating. The coating may be primarily comprised of rosin, and may further comprise NABS, soybean oil, and/or other sustainable oils.Type: ApplicationFiled: June 16, 2022Publication date: August 29, 2024Inventors: Jose FERNANDEZ, Lucas R. MOORE, Paul A. WILLIAMS, Christina KONECKI
-
Publication number: 20240286972Abstract: Disclosed in the present invention is a thermoplastic composite solid propellant, which comprises, by mass: 5-16% of a thermoplastic elastomer having a bonding function; 5-25% of a plasticizer; 5-18% of a metal fuel; 50-70% of an oxidizing agent; and 0.4-5% of a functional auxiliary agent. In the thermoplastic composite solid propellant, a thermoplastic elastomer grafted or copolymerized with a bonding functional group is used as an adhesive, and an adhesive matrix and a solid filler have relatively strong interaction, such that an interfacial effect is enhanced, and the phenomenon of “dehumidification” in the tensile failure process can be slowed down. Further disclosed is a method for preparing the thermoplastic composite solid propellant. The method overcomes defects in the prior art, safely and efficiently prepares the thermoplastic composite solid propellant in an acoustic resonance mixing manner, and meets the requirements of a solid engine for rapid charging.Type: ApplicationFiled: April 15, 2024Publication date: August 29, 2024Applicant: HUBEI INSTITUTE OF AEROSPACE CHEMICAL TECHNOLOGYInventors: Pu Huang, Wei Li, Wei Wang, Yu Shi, Ke Shi, Xiaomeng Fu, Chuntao Li, Fang Wang, Yanwei Wang, Xinke Sun
-
Publication number: 20240286973Abstract: Processes for converting a hydrocarbon reactant into an alcohol compound and/or a carbonyl compound are disclosed in which the hydrocarbon reactant and a supported transition metal catalyst—containing molybdenum, tungsten, or vanadium—are irradiated with a light beam at a wavelength in the UV-visible spectrum, optionally in an oxidizing atmosphere, to form a reduced transition metal catalyst, followed by hydrolyzing the reduced transition metal catalyst to form a reaction product containing the alcohol compound and/or the carbonyl compound.Type: ApplicationFiled: May 9, 2024Publication date: August 29, 2024Inventors: Masud M. Monwar, Jared L. Barr, Carlos A. Cruz, Kathy S. Clear, Max P. McDaniel, William C. Ellis
-
Publication number: 20240286974Abstract: A method for producing a hydrocarbon, including: preparing a molten salt containing an oxide of a first metal; adding carbon dioxide to the molten salt; obtaining precipitates containing a first metal carbide by applying a voltage to the molten salt containing carbon dioxide; and obtaining a gas containing a hydrocarbon and a hydroxide of the first metal by hydrolyzing the first metal carbide.Type: ApplicationFiled: March 28, 2024Publication date: August 29, 2024Applicants: THE DOSHISHA, DAIKIN INDUSTRIES, LTD.Inventors: Takuya GOTO, Takashi WATANABE, Yuta SUZUKI, Haruka FUKUDA, Atsuya YAMADA, Tomohiro ISOGAI, Yosuke KISHIKAWA, Akiyoshi YAMAUCHI
-
Publication number: 20240286975Abstract: The invention relates to a method for producing hydrocarbons including carrying out an electrolysis of water, where hydrogen and oxygen are produced and generating a carbon source, producing the hydrocarbons from the hydrogen and the carbon dioxide where at least some of the produced hydrocarbons are provided in the form of liquid hydrocarbons and an exhaust gas is formed together with the hydrocarbons. The method also includes separating the exhaust gas from the liquid hydrocarbons and recycling exhaust gas in that a reaction of the exhaust gas with the oxygen and/or water, whereby recycled products are formed which have carbon dioxide and/or carbon monoxide, water, and optionally hydrogen.Type: ApplicationFiled: March 25, 2022Publication date: August 29, 2024Inventor: Markus Kinzl
-
Publication number: 20240286976Abstract: An ethylene production apparatus for producing ethylene from a methane-containing gas includes a ceramic membrane having at least one of oxide ion conductivity and proton conductivity; a first catalyst layer that is disposed on a first face of the ceramic membrane and includes a catalyst for accelerating oxidative-coupling-of-methane reaction; a methane supply unit that supplies the methane-containing gas to a space located on the same side as the first face of the ceramic membrane; and a charge transfer unit that transfers an electron from the first face to a second face of the ceramic membrane or transfers a hole from the second face to the first face. The ethylene production apparatus produces ethylene in the first catalyst layer upon supply of the methane-containing gas from the methane supply unit.Type: ApplicationFiled: June 16, 2022Publication date: August 29, 2024Applicant: NITERRA CO., LTD.Inventors: Shuntaro WATANABE, Yosuke NAKAMURA, Hisashi KOZUKA
-
Publication number: 20240286977Abstract: The addition of small amounts of alkaline earth metal oxides (CaO, MgO) as the isomerization function and transition metal oxides (such as MoO3, WO3) as the metathesis function significantly enhances the production of propylene using zeolites. Once the light olefins are formed by cracking on the acid sites of the zeolite, the 1-butene molecules undergo isomerization catalyzed by alkali earth metal oxides and then react with ethylene to produce more propylene.Type: ApplicationFiled: February 10, 2024Publication date: August 29, 2024Inventors: Mitrajit Mukherjee, Vamsi M. Vadhri, Narenda Joshi
-
Publication number: 20240286978Abstract: A process for the purification of isobutene from a C4 stream with at least 1-butene, 2-butene, isobutane and isobutene includes isomerizing 1-butene from a stream of material which is concentrated in isobutane and isobutene obtained from the C4 stream into 2-butene, using a catalyst in an isomerization reactor; supplying a product stream from the isomerization reactor to a rectification column; and providing a stream of material which is concentrated in isobutene. A processing facility is utilized for the purification of isobutene from the C4 stream.Type: ApplicationFiled: May 7, 2024Publication date: August 29, 2024Inventors: Suman THOTLA, Pawel Tadeusz CZAJKA, Stefan Manfred ISELBORN, Kai-Uwe WEMHÖNER, Jürgen POPP
-
Publication number: 20240286979Abstract: A method of absorbing a solvent from a gas stream may involve flowing a gas stream comprising air and a hydrocarbon through an absorption column in a countercurrent direction with a first lean absorbent liquid to absorb solvent out of the gas stream and generate a first conditioned gas stream and a first rich absorbent liquid. The method can then involve flowing the first conditioned gas stream through the absorption column in a co-current direction with a second lean absorbent liquid to absorb solvent out of the first conditioned gas stream and generate a second conditioned gas stream having a reduced concentration of the hydrocarbon than the first conditioned gas stream and a second rich absorbent liquid.Type: ApplicationFiled: February 28, 2024Publication date: August 29, 2024Inventors: Benjamin Wayne Floan, Jeff Kraker, Jeff Garritsen, Wade Steven Martinson, Revathi Panuganti
-
Publication number: 20240286980Abstract: Provided is a production method that enables simple and efficient production of a fluorinated hydrocarbon by a gas phase flow method without using a catalyst. The method of producing a fluorinated hydrocarbon includes continuously supplying a gaseous fluorine-containing inorganic compound to an electrical discharge zone in a plasma apparatus and subsequently causing migration to outside of the electrical discharge zone in the plasma apparatus, continuously supplying a feedstock gas containing an inert gas and a compound represented by formula 1: CH3—R (R is a hydrogen atom, a chlorine atom, a bromine atom, an iodine atom, or an organic group other than a hydrocarbon group) to outside of the electrical discharge zone in the plasma apparatus, and subsequently continuously releasing, to outside of the plasma apparatus, gas that is contained outside of the electrical discharge zone in the plasma apparatus.Type: ApplicationFiled: May 19, 2022Publication date: August 29, 2024Applicants: ZEON CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Go MATSUURA, Keita INADA, Takayuki WATANABE, Manabu TANAKA, Kazuki MATSUI
-
Publication number: 20240286981Abstract: Organic intermediate synthesis, and provides a method for light-promoted oxidation of a compound containing a saturated carbon-hydrogen bond, comprising mixing a compound containing a saturated carbon-hydrogen bond with a catalyst, and oxidizing the compound containing a saturated carbon-hydrogen bond in an oxygen or air atmosphere at a temperature of 20° C. to 100° C. under light irradiation to generate an oxidation product. A method for the light-promoted direct oxidation of a compound containing a saturated carbon-hydrogen bond, which only requires a relatively low temperature to be carried out, has good compatibility with functional groups, short reaction time, high reaction efficiency, low reaction costs, high added value, simple operation and good safety, and is a mild, green and environmentally friendly oxidation method.Type: ApplicationFiled: April 14, 2022Publication date: August 29, 2024Inventors: Zhangjie SHI, Shengming MA, Feng LIU, Hao YU, Changcheng WANG, Qi LIU, Zhen ZHANG
-
Publication number: 20240286982Abstract: Process for producing methane or methanol, said process comprising the steps of: i) conducting a solid renewable feedstock to a thermal decomposition step, this being a pyrolysis step or a hydrothermal liquefaction step, for producing: a first off-gas stream comprising hydrocarbons, a solid carbon stream, and optionally a first liquid oil stream; upgrading the first off-gas stream by conducting it to a hydro/deoxygenation (HDO/DO) step i.e.Type: ApplicationFiled: June 28, 2022Publication date: August 29, 2024Applicant: Topsoe A/SInventors: Magnus Zingler STUMMANN, Troels Dahlgaard STUMMANN
-
Publication number: 20240286983Abstract: The present disclosure provides a preparation system and a preparation method for xylitol crystals. In the preparation system, outlets of a first centrifuge are connected with an inlet of a hot air drying tank and an inlet of a primary mother liquor storage tank through pipelines, respectively. Outlets of a second centrifuge are connected with an inlet of a second fluidized bed dryer and an inlet of a secondary mother liquor storage tank through pipelines, respectively. An outlet of a dicrystalline sugar dissolution tank is connected with an inlet of a blending tank through pipeline. An outlet of a tricrystalline sugar dissolution tank is connected with the inlet of the primary mother liquor storage tank. The blending tank is provided with an inlet for a raw material of xylitol hydrogenation solution. An output of an outlet of a first fluidized bed dryer is prepared xylitol crystals.Type: ApplicationFiled: May 6, 2024Publication date: August 29, 2024Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.Inventors: Qiang WU, Mian LI, Wulong YANG, Fuan WAN, Weidong XU, Shufang QIN, Hang YUE, Weijia WANG
-
Publication number: 20240286984Abstract: Disclosed is a preparation system and a preparation method for high-quality xylitol crystals. The preparation system comprises a blending tank, a heat exchanger, a decolorization tank, an ion exchange system, a microporous filter, a first evaporator, a first crystallization kettle, a first centrifuge, a fluidization drying bed, a xylitol dissolution tank, a second evaporator, a second crystallization kettle, a second centrifuge, a hot air drying tank, and a cold air fluidization bed sequentially connected through pipelines. Liquid outlet of the first centrifuge is connected with first inlet of the blending tank. Liquid outlet of the second centrifuge is connected with first inlet of the xylitol dissolution tank. The blending tank is provided with second inlet for receiving xylitol hydrogenation solution. The xylitol dissolution tank is provided with water inlet for pure water. The material output from a product outlet of the cold air fluidization bed is xylitol crystal product.Type: ApplicationFiled: May 7, 2024Publication date: August 29, 2024Applicant: ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD.Inventors: Qiang WU, Mian LI, Wenyao ZHANG, Wulong YANG, Weidong XU, Shufang QIN, Ni ZHEN
-
Publication number: 20240286985Abstract: A process for producing an ether including treating (a) an ester with (b) hydrogen in the presence of (c) a heterogeneous catalyst to reduce the ester by hydrogenation to form an ether product, wherein the heterogeneous catalyst comprises a transition metal deposited on a sulfonic acid functionalized SiO2 support.Type: ApplicationFiled: November 2, 2022Publication date: August 29, 2024Inventors: Jing Luo, Xue Chen, David G. Barton, David W. Flaherty, Claudia Eugenia Berdugo-diaz, Yangsik Yun
-
Publication number: 20240286986Abstract: A process for purifying halogenated alkoxyethane of general formula XClHC—CF2OR, where X is —Cl or —F and OR is C1-4 alkoxy, from a reaction mixture derived from a batch synthetic procedure for producing the halogenated alkoxyethane, the process comprising the steps of: (a) adding one of an amine and an acid to the reaction mixture, (b) adding a polar liquid to the mixture obtained in step a) to induce phase separation and formation of a polar phase and a separate organic phase, the organic phase containing the halogenated alkoxyethane, and (c) adding the other of the amine and the acid not used step (a) to the organic phase obtained in step (b) to thereby purify the halogenated alkoxyethane.Type: ApplicationFiled: June 17, 2022Publication date: August 29, 2024Inventors: John TSANAKTSIDIS, Cecily ELDRIDGE
-
Publication number: 20240286987Abstract: The invention provides methods of preparing 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid and methods of making a pharmaceutical material comprising a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Also provided are compositions and pharmaceutical materials including a purified amount of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid as well as methods of treating various diseases and conditions using the compositions and pharmaceutical materials.Type: ApplicationFiled: April 11, 2024Publication date: August 29, 2024Inventors: Richard Copp, Mohamed Abdelnasser, Christopher M. Cimarusti, Jonathan Lane, Michael Barkman, Rasidul Amin, Arthur John Cooper, Damodaragounder Gopal, Philipp Selig
-
Publication number: 20240286988Abstract: The present invention relates generally to gas phase processes for producing carboxylic acids or alkyl esters. In one embodiment, a gas phase process for producing a carboxylic acid or an alkyl ester comprises (a) providing a catalyst support comprising deposits of cobalt thiocyanate on at least a portion of the catalyst support; (b) heating the catalyst support to convert the cobalt thiocyanate on the support to cobalt sulfide to form a supported cobalt sulfide catalyst; and (c) reacting alkene gas, steam or an alkanol gas, and a carbon-containing gas in the presence of the supported cobalt sulfide catalyst in a reactor to form a product stream, wherein the carbon-containing gas comprises carbon monoxide or a mixture of carbon monoxide and carbon dioxide, wherein when steam is used as a reactant, the product stream comprises a carboxylic acid, and wherein when alkanol gas is used as a reactant, the product stream comprises an alkyl ester.Type: ApplicationFiled: June 2, 2022Publication date: August 29, 2024Inventors: Alexey Kirilin, Beata A. Kilos, Wen -Sheng Lee, David G. Barton
-
Publication number: 20240286989Abstract: The present invention relates to a process of recovering 3-hydroxypropionic acid, comprising: forming a 3-hydroxypropionate crystal in a concentrate containing 3-hydroxypropionic acid in the presence of an alkali metal salt; preparing a solution containing the 3-hydroxypropionate crystal separated from the concentrate; and adding ammonia to the solution containing the 3-hydroxypropionate crystal, and a slurry composition comprising a precipitate prepared in the process of recovering 3-hydroxypropionic acid, and 3-hydroxypropionic acid.Type: ApplicationFiled: November 24, 2022Publication date: August 29, 2024Applicant: LG CHEM, LTD.Inventors: Yongju BANG, Jeong Eun KIM, Jae Hoon CHOE, Donggyun KANG, Woochul JUNG, Sang Won HAN, Taeho KIM
-
Publication number: 20240286990Abstract: The present invention relates to a vinyl keto ester and intermediates of its synthesis, wherein the vinyl moiety of the vinyl hydroxy ester and of the intermediates is partly or fully deuterated. Furthermore, the present invention relates to two alternative methods of preparing said vinyl keto ester. The first method is a multi-step approach comprising the steps of providing a carboxylic acid that comprises a geminal diol moiety protected by a photolabile protecting group, vinylating said carboxylic acid using vinyl acetate, and cleaving the protecting group by applying UV light. The second method is a one-step approach of reacting a carboxylic acid that comprises an additional carbonyl moiety with acetylene in the presence of a metal catalyst. In both methods, the compounds used may be fully or partly deuterated.Type: ApplicationFiled: June 16, 2022Publication date: August 29, 2024Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.Inventors: Stefan GLÖGGLER, Sergey KORCHAK, Anil P. JAGTAP, Philip SAUL, Denis MOLL
-
Publication number: 20240286991Abstract: The present invention is directed to a method for continuous production of cationic lipids. Said cationic lipids are particularly useful in combination with other lipid components for forming lipid nanoparticles with oligonucleotides (e.g. mRNA) to facilitate delivery of therapeutically active nucleic acids.Type: ApplicationFiled: June 24, 2023Publication date: August 29, 2024Inventors: Peter Seeberger, Matthew Plutschack, Dario Cambie, Jakob Wolf
-
Publication number: 20240286992Abstract: An adduct of ethylenediamine disuccinic acid or a salt thereof and a further polycarboxylic acid or a salt thereof wherein the further polycarboxylic acid is selected from citric acid, polyaspartic acid, tartaric acid, malonic acid, maleic acid, carboxymethyl inulin, oxalic acid, glutaric acid, adipic acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, malic acid and fumaric acid; and wherein said adduct is in the form of a free flowing particulate solid; wherein EDDS is present in the adduct in a molar excess compared with the further polycarboxylic acid.Type: ApplicationFiled: June 13, 2022Publication date: August 29, 2024Inventor: Matthew Robert GILES
-
Publication number: 20240286993Abstract: The invention provides a non-distillative process for manufacturing amphetamine and substituted amphetamines, comprising obtaining a highly pure phosphoramidate compound, converting the highly pure phosphoramidate compound to an amphetamine sulfate compound, concentrating the amphetamine sulfate compound in isopropanol, and then salting out the amphetamine compound directly to obtain an amphetamine salt, the amphetamine salt selected from amphetamine saccharate, amphetamine sulfate, amphetamine aspartate, alkyl-amphetamine saccharate, alkyl-amphetamine sulfate, alkyl-amphetamine aspartate, aryl-amphetamine saccharate, aryl-amphetamine sulfate, aryl-amphetamine aspartate, and mixtures thereof.Type: ApplicationFiled: February 22, 2023Publication date: August 29, 2024Inventors: Harold MECKLER, Darryl CLEARY, Karl POPP, Heidi SCHLAGER, Mozhgan NAVIDI, Joshua MALONE
-
Publication number: 20240286994Abstract: The present invention relates to a novel squaramide derivative and a use thereof and provides a novel derivative through the strategy of replacing a compound having a urea core with the bioisolate squaramide, whereby the derivative exhibits an anticancer activity through eIF2? phosphorylation efficacy, wherein squaramide has a characteristic structure retaining a double bond linked to the carbonyl groups and the squaramide structure can be prepared by mediating a precursor bearing an amine group to the squarate ring, which is a squaric ring, through a conjugate addition reaction.Type: ApplicationFiled: May 31, 2022Publication date: August 29, 2024Applicants: PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, KOSIN UNIVERSITY INDUSTRY-ACADEMY COOPERATIONInventors: Hwayoung YUN, Jee-Yeong JEONG, Jinsook KWAK, Min Jung KIM, Soyeong KIM
-
Publication number: 20240286995Abstract: Disclosed herein is a compound of Formula (I), wherein Q+ is a cation. The compound of Formula (I) has at least 50 wt-% bio-based carbon content, relative to the total mass of carbon in the compound.Type: ApplicationFiled: June 24, 2022Publication date: August 29, 2024Applicant: Clariant International LtdInventors: Catherine BREFFA, Carsten COHRS
-
Publication number: 20240286996Abstract: The present disclosure provides naphthalenesulfonyl compounds, preparation methods and application thereof. Specifically disclosed is a compound of formula (I) or a salt thereof, which serves as a specific derivatization reagent capable of reacting with hydroxyl and amino groups. The compound features simple synthesis, high reactivity, and ready availability at low cost, and is capable of improving chromatographic separation behaviors of target compounds and enhancing the detection sensitivities of these compounds.Type: ApplicationFiled: February 7, 2024Publication date: August 29, 2024Applicant: FUDAN UNIVERSITYInventors: Huiru TANG, Pengcheng LI
-
Publication number: 20240286997Abstract: The present invention relates to a process for preparing at least one mercaptan, comprising the following steps: i) treatment of a catalyst for the sulfhydrolysis of at least one dialkyl sulfide, preferably a zeolite, said treatment comprising the following steps: 1) heating said catalyst, preferably in the presence of an inert gas; and 2) placing said catalyst in contact with hydrogen sulfide (H2S); and then ii) a sulfhydrolysis reaction in which at least one dialkyl sulfide is reacted with H2S in the presence of said catalyst treated according to step i), to obtain at least one mercaptan; said catalyst being a zeolite.Type: ApplicationFiled: June 20, 2022Publication date: August 29, 2024Applicant: ARKEMA FRANCEInventors: Hélori SALEMBIER, Georges FREMY, Guillaume LAUDUMIEY, Louis CORBEL DEMAILLY
-
Publication number: 20240286998Abstract: The present disclosure relates in one aspect to fluorinated tryptamine compounds, or analogues thereof, and compositions comprising the same. Compounds of the disclosure can be used to treat, prevent, and/or ameliorate a psychiatric disease or disorder in a subject.Type: ApplicationFiled: June 2, 2022Publication date: August 29, 2024Inventors: Jason Wallach, Michael Dybek
-
Publication number: 20240286999Abstract: The present invention provides a new azabicyclo[3.1.0]hexane compound that is represented by the following formula: and that is for use in treating central nervous system (CNS) disorders. In the formula, X represents —C(?)—O— or the like, and R represents H, an optionally substituted C1-C18 alkyl, or the like.Type: ApplicationFiled: June 14, 2022Publication date: August 29, 2024Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Minoru OKADA, Nobuaki ITO, Masakazu SHIBATA
-
Publication number: 20240287000Abstract: An acetylsalicylic acid derivative and an application thereof. The present disclosure relates to the field of chemical pharmaceuticals, and in particular, to a compound shown in formula (I) or pharmaceutically acceptable salts thereof.Type: ApplicationFiled: April 15, 2024Publication date: August 29, 2024Inventor: Jing ZHANG
-
Publication number: 20240287001Abstract: The present invention relates to a crystalline form of compound (I) and a method of making the crystalline form of compound (I). The invention also provides pharmaceutical compositions comprising the crystalline form of compound (I). Furthermore, the invention relates to methods of using this crystalline form of compound (I) as a medicament and in the treatment of a disease involving abnormal levels of glucosylceramide and/or higher levels of glycosphingolipids.Type: ApplicationFiled: October 1, 2021Publication date: August 29, 2024Inventors: Robert Hett, Fritz Blatter, Jennifer Robin, Kyle Landskroner
-
Publication number: 20240287002Abstract: The invention relates to metabolites of cabozantinib (I) as well as uses thereof.Type: ApplicationFiled: April 22, 2024Publication date: August 29, 2024Inventors: Dana T. Aftab, Sriram Naganathan, Wei Xu, Steven Lacy, Linh Nguyen
-
Publication number: 20240287003Abstract: A novel compound of formulae (I) or (II), to the use thereof as a drug, particularly for the treatment of SARS-COV-2, for the treatment of COVID-19 disease and any diseases related to beta-coronaviruses, and for the in vitro application thereof in order to study the interaction with Mpro protease.Type: ApplicationFiled: May 10, 2022Publication date: August 29, 2024Inventors: Saïd EL KAZZOULI, Nadia TOUIL, Elmostafa EL FAHIME, Abdelmoula EL ABBOUCHI, Mouhssine HEMLALI, Nabil EL BRAHMI, Abdelaziz EL ALAOUI, Salim BOUNOU, Mostapha BOUSMINA
-
Publication number: 20240287004Abstract: Provided herein are small molecule inhibitors for the targeting or IRE1 protein family members. Binding may be direct or indirect. Further provided herein are methods of using IRE1 small molecule inhibitors for use in treating or ameliorating cancer in a subject. Moreover, IRE1 small molecule inhibitors described herein are for the treatment of cancer, where the cancer is a solid or hematologic cancer.Type: ApplicationFiled: January 12, 2024Publication date: August 29, 2024Inventors: Joseph P. Vacca, Sarah Elizabeth Bettigole
-
Publication number: 20240287005Abstract: The present invention provides compounds of formula (I): which are useful for long-lasting treatment and control of pests, for example fleas and ticks, in companion animals and livestock, and pharmaceutical compositions and methods of using the same.Type: ApplicationFiled: June 15, 2022Publication date: August 29, 2024Inventors: Pierre DUCRAY, Denise RAGEOT, Andreas TURBERG
-
Publication number: 20240287006Abstract: The present disclosure provides pharmaceutical compositions and drug delivery devices comprising a compound of formula I, II, III, or IV. Methods are provided for inhibiting activity of an E3 ligase, involving contacting the E3 ligase with a compound of formula I, II, III, or IV. The present disclosure provides various treatment methods involving administration of such compounds.Type: ApplicationFiled: June 16, 2022Publication date: August 29, 2024Inventors: Michael Rape, Julia Sabine Schaletzky, Edward Eric Wehri, Andrew Garrett Manford
-
Publication number: 20240287007Abstract: There are described benzamides of the general formula (I) as herbicides. In this formula (I), X, R and Z are radicals such as alkyl and halogen.Type: ApplicationFiled: July 4, 2022Publication date: August 29, 2024Inventors: Hartmut AHRENS, Arnim KÖHN, Harald JAKOBI, Christian WALDRAFF, Elisabeth ASMUS, Birgit BOLLENBACH-WAHL
-
Publication number: 20240287008Abstract: Provided are methods of preparing 3-R-1,4,2-dioxazol-5-one compounds using convenient and efficient methods. Also provided are 3-R-1,4,2-dioxazol-5-one compounds produced using the methods described.Type: ApplicationFiled: April 23, 2024Publication date: August 29, 2024Inventors: David S. Hall, Jeffery Raymond Dahn, Toren Hynes
-
Publication number: 20240287009Abstract: Disclosed herein are addition-polymerizable monomer composition including an amine-derivatized alpha-methyl styrene (ADAMS) monomer according to structure (I) and/or an aminated conjugated aliphatic methylated polyene (ACAMP) monomer according to structure (II): with k, R1, R2, R3, and R4 defined herein. Difunctional monomers of these types with two polymerizable loci and/or two amine loci are also disclosed herein. Further disclosed herein are methods for making such compositions.Type: ApplicationFiled: January 12, 2024Publication date: August 29, 2024Applicant: Infineum International LimitedInventors: Evan A. HAIDASZ, Robert A. Clarkson, Michael A. Collins, BENJAMIN G. N. CHAPPELL
-
Publication number: 20240287010Abstract: Described herein are methods for making intermediates in the production of fragrance ingredients starting from ?-farnesene. In particular, methods for making acetylmethylfarnesol and hydroxy-farnesylacetone are described. Methods for making other intermediates in the process are also described. In addition, compositions comprising intermediates in the process and uses of the intermediates are described.Type: ApplicationFiled: June 21, 2022Publication date: August 29, 2024Inventors: Giacomo PERSIANI, Corinne BAUMGARTNER, Thierry GRANIER, Martin LOVCHIK, Fridtjof SCHROEDER
-
Publication number: 20240287011Abstract: The present invention relates to a method for producing tetrahydrofuran, gamma-butyrolactone, or 1,4-butanediol. Particularly, according to an embodiment of the present invention, by using polyhydroxyalkanoate (PHA), the yield of tetrahydrofuran, gamma-butyrolactone, or 1,4-butanediol which is environmentally friendly due to excellent biodegradability and biocompatibility can be effectively controlled without complicated additional processes.Type: ApplicationFiled: June 22, 2022Publication date: August 29, 2024Applicant: CJ CHEILJEDANG CORPORATIONInventors: Jang-Woo SEO, Jinwoo JEON, Youngsu YOU, Joo Young LEE, Jieun KIM