Abstract: The present disclosure provides a clean-and-care appliance, and a transducer device and a pressure alarm mechanism therefor. The transducer device according to the present disclosure comprises a transducer, and an elastic assembly comprises at least one proximal elastic member and at least one distal elastic member; the proximal elastic member and the distal elastic member are respectively provided with a first edge and a second edge; the first edge is fixedly connected to a driving shaft to move along with the driving shaft, and the second edge forms a fixed edge when the proximal elastic member and the distal elastic member are elastically deformed; the plane of the proximal elastic member forms a first angle with respect to a median plane of a rack, and the plane of the distal elastic member forms a second angle with respect to the median plane.

Abstract: An apparatus includes a toothbrush head having a stem, an appliance brush, and a body configured to be releasably coupled with either one of the toothbrush head and the appliance brush. The body includes an extension and at least a portion of a side of the extension is configured to be covered by the stem when the toothbrush head is coupled with the body. The appliance brush is configured to couple to the extension when the toothbrush head is not coupled with the body.

Abstract: A bodily fluid transporting unit that includes a container with a syringe housing and a refrigerant pack in the container. The container is covered by a lid and the engagement of the container and the lid results in an air-tight and moisture-tight bodily fluid transporting unit.

Abstract: The present invention relates to a device (1) for containing animals and keeping them asleep during their irradiation by a proton beam. The animals are located in compartments (21) and kept asleep with an anesthetic gas provided to them by a dispenser (3). The device (1) is sealed, which prevents escape from the animals and leakage of anesthetic gas.

Abstract: An auxiliary pressure device for stress urinary incontinence includes: an expansion body with a structure for insertion into the vagina, a first state before insertion into the vagina, and a second state after insertion into the vagina; an adjustment system for maintaining and/or releasing the first state of the expansion body; and a force application part connected to the expansion body, with a traction structure for the user to apply force to move the expansion body out of the vagina. The auxiliary pressure device includes an adjustment system. The adjustment system improves the convenience of the expansion body entering the vagina through the imparting of the first state and the comfort during insertion into the vagina, and the positional stability of the expansion body in the vagina to avoid discomfort caused by position changes during use, as well as embarrassment caused by accidental falling off, minimizing the doctor's intervention.

Abstract: Provided is a medical device formed entirely from or formed partially from a polymer, e.g., a polysaccharide such as chitosan. In some embodiments, the medical device may be formed as a tubular member formed from a sheet of a chitosan material. This chitosan tube may be used to wrap around tissue, such as a nerve or tendon to help with the regeneration or healing process of the nerve or tendon, as applicable.

Abstract: An operation device configured to be joined with a proximal portion of a treatment device having a lumen through which a wire extending from an indwelling unit indwelling in a living body lumen to the outside of the body, and includes: a housing including a joining portion to which the treatment device can be joined; and an action unit that is disposed on the proximal side of the joining portion, and the action unit is brought into contact with the wire extending from the treatment device, to apply, to the wire, a moving force for the wire to move in the longitudinal axis direction.

Abstract: A system and method of remote guidance and alignment for endovascular fenestration of a vascular prothesis placed intraluminally that includes a flexible magnetic guide sheath having a magnetic distal end. An implantable magnetic stent for intraluminal placement in proximal end of a target artery providing magnetic guidance outside the endovascular aortic stent graft prothesis for accurate aperture formation in the vascular prothesis for subsequent placement of covered branch stents thereto.

Abstract: Devices, systems and/or methods for repairing soft tissue adjacent a soft tissue repair site. In one embodiment, a repair device configured to couple to soft tissue is provided. The repair device includes a capture portion and an anchor portion. The capture portion configured to extend with radial portions. The anchor portion includes a base with multiple legs extending therefrom. The multiple legs are configured to move from a linear position to a formed position such that, in the formed position, the multiple legs couple to structure of the capture portion.

Abstract: Disclosed herein are intraocular lenses comprising an optic portion and at least one haptic having a proximal end coupled to the optic portion and a distal end. The haptic comprising a haptic lumen extending through at least part of the haptic. The haptic can comprise one or more haptic isolators disposed within the haptic lumen. The one or more haptic isolators can be configured to counteract or reduce unintended shape changes caused by an external energy directed at the haptic.

Abstract: Disclosed herein are intraocular lenses with features that counteract the effects of anterior capsular contraction and methods for implanting such intraocular lenses. In some embodiments, the intraocular lenses can comprise an optic fluid chamber and a haptic having a haptic fluid lumen in fluid communication with the optic fluid chamber. The haptic fluid lumen can comprise a thickened anterior portion such that a thickness of the anterior haptic wall of the haptic is greater than the thickness of the posterior haptic wall. Moreover, the intraocular lenses can comprise one or more support columns disposed within the haptic fluid lumen. The support columns and/or the thickened anterior portion of the haptic can maintain a shape of the haptic fluid lumen in response to forces applied to the haptic as a result of anterior capsular contraction.

Abstract: Methods, devices and systems for anchoring and/or sealing a heart valve prosthesis and, in particular, a mitral valve prosthesis (202). Inflatable elements (204, 206) are used to seal and anchor the mitral valve prosthesis (202) and/or other elements associated with repairing a native mitral valve.

Abstract: A prosthetic heart valve includes a sealing feature coupled to the inner frame at a coupling point and extending between the coupling point and a point of the outer frame that is radially outward of the coupling point in a direction substantially orthogonal to the longitudinal axis, the sealing feature comprising a plurality of layers.

Abstract: A prosthetic heart valve includes a frame made of a plastically expandable material and including an inflow end, an outflow end, and a central portion between the inflow end and the outflow end. The frame is radially collapsible and expandable. The inflow end includes a plurality of circumferentially extending first strut members having a first strut width and forming a first angle between adjacent first strut members, and the central portion includes a plurality of circumferentially extending second strut members having a second strut width and forming a second angle between adjacent second strut members. A plurality of leaflets is positioned within the frame and configured to regulate blood flow through the prosthetic heart valve. The first strut width of the first strut members at the inflow end of the frame is greater than the second strut width of the second strut members in the central portion of the frame.

Abstract: A prosthetic heart valve for implantation within a native atrioventricular heart valve. The prosthetic heart valve includes a self-expanding frame having an annular main body and a valve member disposed within the main body. The prosthetic heart valve includes an atrial sealing member formed by a fabric cover and a plurality of arms that are arranged side-by-side in a circumferential direction around the main body. The atrial sealing member extends radially outwardly from the main body and a peripheral portion of the atrial sealing member curves upwardly for conforming to surrounding native anatomy. The prosthetic heart valve further includes one or more ventricular anchors extending from the main body for capturing native leaflet tissue and thereby securing the prosthetic heart valve within the native atrioventricular heart valve.

Abstract: Certain examples of the disclosure concern a prosthetic device. The prosthetic device can include a radially compressible and expandable frame and a screw actuator coupled to the frame and configured to be rotated to radially expand the frame from a radially compressed state to a radially expanded state. The frame can include two or more pairs of first markers and second markers. The pairs of first and second markers can be circumferentially spaced apart from each other. The first and second markers of each pair can be axially aligned and axially movable relative to one another as the frame radially expands. Positions of the first and second markers can be configured so that a difference in axial distances between respective pairs of the first markers and second markers can indicate a degree of evenness of the frame's radial expansion.

Abstract: The present disclosure describes devices, systems, and methods for intravascularly delivering an intravascular device to a targeted cardiac valve. In one aspect, a medical device includes a body and a plurality of positional markers positioned on the body, the plurality of positional markers being defined in part by at least one cutout and having at least one parameter selected such that the plurality of positional markers vibrates, in response to an ultrasound signal, at a resonant frequency.

Abstract: A prosthetic heart valve delivery device can include an engagement mechanism that can securely engage with and reliably release a heart valve prosthesis carried thereby. The delivery device can have a docking area defining a longitudinal axis and an engagement wire extending along the longitudinal axis. The engagement wire can have an engaged position in which the engagement wire extends through the docking area to engage with the heart valve prosthesis. The engagement wire can also be moved to a disengaged position to permit disengagement of the heart valve prosthesis from the docking area.

Abstract: A delivery apparatus for a prosthetic heart valve includes a handle with at least one rotatable knob. A pull body is disposed within the cavity and operatively coupled to the knob such that rotation of the knob results in movement of the pull body within the cavity and along a longitudinal axis of the handle. An actuation assembly that can releasably engage an actuator of the prosthetic heart valve includes a sleeve member. An end portion of the sleeve member is disposed within the cavity of the handle and coupled to the pull body such that movement of the pull body by rotation of the knob axially displaces the sleeve member relative to the handle. The sleeve member can be axially displaced to release the actuation assembly from engagement with an actuator of the prosthetic heart valve.

Abstract: Some embodiments of the present disclosure provide a method and system for transcatheter chordae tendineae repair. The method includes: transvascular entering into an atrium of a heart; advancing a leaflet implant from an atrial side of a leaflet of the heart to a corresponding ventricular side, so as to fix the leaflet to a suture attached to the leaflet implant, where a proximal end of the suture extends out of a body to connect with a ventricular implant; delivering the ventricular implant from the atrium to a corresponding ventricle, and anchoring the ventricular implant to ventricular tissue of the corresponding ventricle; adjusting the suture to an appropriate tension; and actuating the ventricular implant to retain the suture at the ventricular implant under the appropriate tension.

Abstract: An articulating implant holder system for heart valve repair or replacement has an implant configured to be secured to a heart valve annulus, an implant holder secured to the implant, an articulating handle assembly comprising a handle, a swivel pivotably secured to the handle at a first location and a connector pivotably secured to the swivel at a second location, an actuating cable secured between the handle and the connector to cause the swivel to move from a first position to a second position, and a latch removably secured to the implant holder. A plurality of sizer heads are configured to correspond to different sizes of heart valve annuluses and each of the plurality of sizer heads has a latching feature. A latching feature of the swivel is configured to removably snap on to the latching feature of each of the plurality of sizer heads and is configured to permanently snap on to the latch.

Abstract: A personalized implant for bone replacement comprises an implant body as a reconstruction of a bone portion. The implant body comprises a closed cavity and a solid impervious layer of material defining an outside surface of the implant body exposed to an exterior of the implant. The solid impervious layer fully encloses the closed cavity inside the implant body. The closed hollow interior can comprise an open support structure to reinforce the solid outside layer.

Abstract: Various implementations include a method for treating a bone defect of a first bone structure and a second bone structure of a patient. The method includes positioning a biodegradable scaffold within a passage of a biodegradable sleeve, wherein the passage extends from a first end to a second end of the biodegradable sleeve, wherein a geometry of the biodegradable sleeve induces strain on a portion of the biodegradable scaffold when a force is applied to the biodegradable sleeve; and positioning the biodegradable sleeve along the first bone structure and the second bone structure to span the bone defect.

Abstract: The disclosure includes methods and systems for making orthopedic connections where there is unique adjustability to the connection. Illustratively, one embodiment provides a connecting assembly for connecting a plurality of orthopedic components. Such connecting assemblies can include a first orthopedic component that provides a female bore. Additionally, the assembly can include a second orthopedic component that can be or include a male-type connecting member that is positionable in the bore of the first orthopedic component. In one preferred form, the male-type connecting member will be a quasi-spherical member. The quasi-spherical member can include a textured outer surface, e.g., for contacting one or more walls or surfaces in the bore in a fashion that removably locks or helps to removably lock or fix the quasi-spherical member in the bore.

Abstract: An implant adapted to be attached to an implant receiving surface in a joint of a patient is provided. The implant includes a bone contacting surface, and at least one implant peg extending from the bone contacting surface, wherein both the bone contacting surface and a part of a surface area of the implant peg includes an osseointegrating structure, such as e.g. a lattice structure or a random lattice structure.

Abstract: A computer-implemented bone-implant system evaluation method for application of mesh-free analysis of a bone-implant system for evaluation of performance of a bone-implant system for an implant implanted within the bone structure at an anatomical site, said method comprising (i) receiving a set of bone structure data set, wherein set of bone structure data includes data indicative of the bone structure at an anatomical site; (ii) inputting an implant data set and inputting the position of the implant data set, wherein the implant is selected based upon the biomechanical requirements for the anatomical site and the position and of the implant data set is indicative of the position of the implant with respect to the anatomical site, wherein implant data set includes data representative of the geometry and materials properties of the implant; (iii) creating a bone-implant model, wherein said bone implant-model includes a mesh-free model of trabecular bone at the anatomical site wherein the bone-implant model is

Abstract: A preconfigured, customizable intraoperative mold for the assembly of implants having uniform coating(s). One or more plugs are adapted to prevent incursion of coating material into engineered or other openings in the implant. The dimensions of these plugs, or other standoffs, is chosen to control spacing of the implant away from the interior surfaces of the mold. The plugs and/or standoffs thus further control a thickness, profile, distribution, types, or other configuration of the coating materials.

Abstract: A method for repairing a bone defect of a patient includes providing a ceramic scaffold configured for filling the bone defect, loading the scaffold with growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation, placing the ceramic scaffold with the growth factor transduced cells in or across the bone defect, and stabilizing the ceramic scaffold with the growth factor transduced cells in the patient until the bone defect is healed. An assembly for repairing a bone defect includes a ceramic scaffold configured for spanning the bone defect and a culture of live growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation loaded onto the ceramic scaffold.

Abstract: The invention relates to traumatic surgery and orthopedics and is intended for hip acetabular replacement. In a spherical cup of an acetabular implant, in the region of the apex of a hemisphere, a through opening is provided for osteoplasty of the acetabular floor, and the spherical segment of the surface between the edge of the rim of the cup and an opening for a screw for fastening in the ilium is larger than the spherical segments of the surface between said edge and openings for screws for fastening in the pubis and the ischium, thus forming a supporting ledge in the region of the body of the ilium. Said ledge can be extended into the region of an outer spherical surface of the cup which is formed by an angle ? in a range of 1°-30° between diametral planes and which is adjacent to the equatorial plane of the hemisphere.

Abstract: A device provides a variety of fracture fixation options should a fracture occur after total hip arthroplasty or total knee arthroplasty, and provides associated methods and apparatus for application of provided fixation. The ability to pre-engineer fracture fixation contingent solutions into femoral or tibial components provides for a distinct clinical advantage in the planning and execution for periprosthetic fracture fixation. Said methods and apparatus include targeting devices which allow for intimate association of fixed angle locking screws in pre-drilled holes in an existing prosthetic, femoral nail, or other components including additional fixation components. Such apparatus and methods further include the use of alignment devices and other components to allow for ease of repair of fractures utilizing the pre-engineered solutions.

Abstract: An orthopaedic knee prosthesis includes a femoral component having a metal base with a polymer articular layer molded thereto. A method for making a metal-reinforced femoral component of an orthopaedic knee prosthesis is also disclosed.

Abstract: A patella implant for knee arthroplasty includes a cap and a base. The cap has an articulating surface and a plurality of first connection members. The base is to be attached to the backside of a patella of a patient. The base includes a cap support mounted to the cap. The cap support includes a plurality of first connection recesses. Each first connection member of the cap is disposed in a corresponding one of the first connection recesses of the cap support to mount the cap to the base.

Abstract: Spinal surgical procedures for implanting intervertebral devices, and associated devices and systems are described herein. A representative spinal surgical procedure can include gaining access to a diseased disc of a spine of a patient via a minimally-invasive a lateral, transpedicular, transfacet, or transforaminal access pathway. Various instruments can be inserted through the trocar to (i) remove some or all of the diseased disc, (ii) expand a disc space around the diseased disc, (iii) insert an intervertebral device into the disc space, and/or (iv) fill the intervertebral device with a fill material. Each of the aforementioned steps can be performed through the minimally-invasive access pathway provided by the trocar. This can minimize disruption to the flesh of the patient—minimizing patient pain and recovery time.

Abstract: An implant system comprising a staple and a cage is disclosed. The implant system is secured to the bone by moving the staple rotationally and longitudinally whereby tines of the staple and opposing tines frictionally and mechanically engage or embed themselves in the bone side walls. For vertebral applications, the cage defines an upper surface plane, a lower surface plane and a cage surface angle between these two planes whereby the cage surface angle may alter an endplate surface plane of one or more vertebral body when the cage is implanted in a vertebral body. Implant systems may be configured for use as an interbody or intrabody implant system. The implant system may also be configured for use in arthrodesis procedures with other joints within the body. The implant system may further comprise an anchor frame or plate to further secure the cage and staple to the anatomy.

Abstract: An expandable implant includes an upper main support of bone, a lower main support coupled to the upper main support, the lower main support comprising a first coupling feature and a second coupling feature being substantially parallel to the first coupling feature, and a control assembly configured to control relative movement between the upper main support and the lower main support, the control assembly including a first control member configured to engage the upper main support and the lower main support and interface with the first coupling feature a second control member configured to engage the upper main support and the lower main support and interface with the second coupling feature, and a control shaft configured to be received by the first control member and the second control member, wherein manipulation of the control shaft causes relative movement between the upper main support and the lower main support.

Abstract: An interbody spinal cage comprising: a body portion comprising a superior side, an inferior side and at least one lateral side connecting the superior side and the inferior side; and at least one endplate portion coupled to the superior side or the inferior side of the body portion, the at least one endplate portion comprising a unibody structure and operable to be fixedly coupled to an anatomical structure of a patient and decoupled from the superior side or the inferior side of the body portion.

Abstract: A bone fusion method, system and device for insertion between bones that are to be fused together in order to replace degenerated discs and/or bones, for example, the vertebrae of a spinal column. The bone fusion device includes a body and an extendable plate. The bone fusion device is able to be inserted between or replace the vertebrae by using a minimally invasive procedure wherein the dimensions and/or other characteristics of the bone fusion device are selectable based on the type of minimally invasive procedure.

Abstract: An expandable spinal implant is provided having a frame with a distal wall for retaining an expansion plug such that bone growth promoting material may be Introduced to a proximal portion of the implant after expansion. Various implants, systems and methods are disclosed.

Abstract: An orthopaedic surgical instrument for extracting an implanted femoral stem component includes a clamping jaw configured to the clamp the femoral component in the instrument's extraction loop. A leaf spring applies a spring bias to the clamped femoral component. A method of using an orthopaedic surgical instrument to extract an implanted femoral component is also disclosed.

Abstract: The invention is defined by the claims set forth herein; however, briefly, the invention herein is an extractor for a human femoral component with a trunnion neck comprising, a plurality of extractor sections, including a first section with a first axis, a second section with a second axis, and a third section with a third axis; a body with a threaded hole defined therein that is provided with a clamping body section and a central body section, a pivoting member with first end, a second end, and a pivot hole defined thereinbetween that includes a clamping structure located at the second end that is shaped to clamp the trunnion neck of the femoral component; and a pivot that secures the pivoting member to the body by extending through the pivot hole defined in the pivoting member and the pivot hole defined in the fulcrum structure of the body.

Abstract: The present invention provides an expandable fusion device capable of being installed inside an intervertebral disc space to maintain normal disc spacing and restore spinal stability, thereby facilitating an intervertebral fusion. In one embodiment, the fusion device includes a body portion, a first endplate, and a second endplate, the first and second endplates capable of being moved in a direction away from the body portion into an expanded configuration or capable of being moved towards the body portion into an unexpanded configuration. The fusion device is capable of being deployed and installed in both configurations.

Abstract: The invention relates to a casting mold for producing a hip joint spacer, which comprises a head element comprising an upper shell and a lower shell, optionally a neck element, and a stem element, which comprises an upper shell and a lower shell, wherein the casting mold has a latching element, and an upper shell and a lower shell of the head element and/or of the stem element can be connected to one another by means of the latching element.

Abstract: Various aspects of this disclosure relate to a prosthetic cover comprising an array of sensors, which transmit signals to an array of electrodes in a liner that fits over a residual limb of an amputee. Different interactions with the prosthetic cover cause different activation of the electrodes to transmit electrical current through different areas of the residual limb and modulate neurons differently within the residual limb. Various aspects of this disclosure also relate to a prosthetic liner with a substrate that includes electrodes for transcutaneous electrical nerve stimulation and/or electronic muscle stimulation for a residual limb.

Abstract: The inventive technology disclosed herein relates to a novel compression cell device and methods of use thereof comprises: an adaptable compression prosthetic device that may be configured to adaptably secure a residual limb using one or more of compression cells, that may further incorporate a thermal indicator system to identify areas of high and low residual limb engagement with the cells: adaptable compression socket that may be configured to adaptably secure a residual limb using one or more of said novel compression cells that may be further secured in a compression slot and secured by one or more compression cords that is responsive to an compression actuator: said adaptable compression socket that may be further include a thermal surface.

Abstract: A prosthetic device includes a polymer lattice structure. The lattice structure includes a first surface arranged to face toward a residual limb, a second surface arranged to face away from the residual limb, a thickness between the first and second surfaces, and a variable lattice density across the thickness.

Abstract: A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.

Abstract: A vascular prosthesis (e.g., stent), and packaging and delivery system to selectively deliver a vascular prosthesis are described. In some embodiments, the vascular prosthesis utilizes a low porosity and high porosity section, and the packaging and delivery system allows the prosthesis to be delivered such that the position of the low porosity and high porosity sections of the prosthesis can vary.

Abstract: A bidirectional twistable stent is disclosed. The stent comprises a cylinder-shaped stent body having a plurality of axially arranged rows of struts encircling a central lumen and a plurality of flex connectors that connect at least two adjacent rows of struts in such a manner that allows the stent to be twisted clockwise or counter clockwise without causing deformation of any struts in the stent body. Also disclosed are the method of making the stent, method of using the stent, and a kit containing the stent.

Abstract: Embodiments are directed in part to endovascular prostheses and methods of deploying same. Embodiments may be directed more specifically to stent grafts and methods of positioning and deploying such devices within the body of a patient.

Abstract: A stent graft crimping device for radially constricting a stent graft includes a rigid cylinder defining a slot extending parallel to a longitudinal axis of a flexible sheet having a straight edge and a second edge and extending within the rigid cylinder to define a pocket. In a method of use, a stent graft can be positioned within the pocket and radially constricted by pulling on the second edge of the flexible sheet while the straight edge, having a raised component, remains at the slot defined by the rigid cylinder. The stent graft crimping device can be employed independently or as a system in combination with components of a stent graft delivery device.