Abstract: The present invention relates to dental instruments having video capabilities. Specifically, the present invention relates to a dental instrument having a video camera for viewing a user's or patient's mouth when utilizing the dental instrument. More specifically, the dental instrument provides video output to a wireless device, such as a smart phone, tablet computer or other like computer. Methods of using the same are further provided.

Abstract: The technology relates to video laryngoscopes with improved illumination. An example laryngoscope includes a display; a handle; an arm extending distally from the handle; a camera positioned at a distal end of the arm; a light source positioned at the distal end of the arm; and a unibody plug positioned at the distal end of the arm, the unibody plug. The unibody plug includes a light guide formed of a solid transparent material having an entry surface at a proximal end of the light guide and an exit surface at a distal end of the light guide, wherein the entry surface is adjacent the light source; and a frame that defines an air gap around at least 70% of a length of the light guide.

Abstract: An access assembly for a surgical instrument, including: a tube member, a proximal sealing device connecting the surgical instrument to a proximal end of the tube member in a sealed manner, a distal end member connected with the tube member, a fluid supply passage for providing the fluid to the access assembly and a fluid discharge passage for the access assembly to discharge the fluid. The distal end member includes: a tubular housing connected with a distal end of the tube member; and a plurality of sealing valves arranged at a distal end of the tubular housing and configured to open and seal a distal end of the access assembly. At least one sealing valve includes a nozzle for ejecting a fluid, a fluid inlet for receiving the fluid, and a distal end member fluid channel for fluidly communicating the fluid inlet and the nozzle.

Abstract: Provided is a system and method for sensory testing of a user. The method includes: initializing probability matrices based on knowledge of a sensory field; iteratively performing trials at locations in the sensory field until termination criteria have been met, where each trial is conducted at a particular location in the sensory field by providing a particular intensity of a stimulus to the user, each trial including: receiving a result that includes an indication from the user in response to the stimulus; transforming a set of psychometric functions using the result; updating the probability matrices by multiplying the probability matrices by the set of transformed psychometric functions; and generating updated probability distributions of sensory field estimates for locations in the sensory field using the updated probability matrices; determining statistical measures that describe the updated probability distributions; and outputting the statistical measures as estimates of the sensory field.

Abstract: A digital color vision deficiency testing system is disclosed. The system includes an application for providing a plurality of user interfaces for performing color vision testing. A user interface provides, for example, a color matrix having a central color matrix, including a plurality of color combinations, an inner matrix, and an outer matrix. For testing, a user selects a color and, for example selects an interactive marker (i.e., finger, stylus, or mouse) across the central color matrix to dynamically change the color of the inner matrix to match with the color of the outer matrix, wherein the RGB, RGBA, HEX, HSV, HSL, YUV/YCBCR, CIELAB, HSLA, and/or CMYK values are recorded when the user lifts the marker or clicks the mouse (i.e., stops movement). A plurality of iterations is performed and then, the recorded values are compared with stored threshold values for providing an accuracy result to indicate color vision deficiency.

Abstract: An apparatus for measuring a blood flow parameter in a blood vessel, including: an interferometric data collection apparatus including a light source and a sensor coupled to a controller, the controller being configured to: direct the light source toward a proximal side of a blood vessel; obtain interferometric data from a tissue adjacent to and outside of a distal side of the blood vessel opposite the proximal side; determine a signal modulation rate based on the interferometric data; and estimate a blood flow parameter in the blood vessel based on the signal modulation rate.

Abstract: A display system can include a head-mounted display configured to project light to an eye of a user to display virtual image content at different amounts of divergence and collimation. The display system can include an inward-facing imaging system possibly comprising a plurality of cameras that image the user's eye and glints thereon and processing electronics that are in communication with the inward-facing imaging system and that are configured to obtain an estimate of a center of cornea of the user's eye using data derived from the glint images. The display system may use spherical and aspheric cornea models to estimate a location of the corneal center of the user's eye.

Abstract: Systems and methods for detecting multiple physical features is described herein. The method may include receiving a sensor signal from a single optical sensor proximate to a measurement region, determining a plurality of sensor responses from the sensor signal, and generating a plurality of measurement signals from the plurality of sensor responses. Each of the measurement signals may correspond to a different respective physical signal of the measurement region.

Abstract: A display device including: display pixels arranged in a display area of a display panel; light sensing pixels arranged in the display area; a display scan driver configured to drive the display pixels to emit light; a light sensing scan driver configured to drive the light sensing pixels to sense light; and a main driving circuit configured to measure a user's biometric information using light sensing signals received from the light sensing pixels, wherein the main driving circuit displays a preset user behavior guidance program screen during a measurement period of biometric information to guide a user's biometric signal detection process, and displays user behavior guidance information and the biometric information measurement result using the biometric signal in real time.

Abstract: A dental and facial imaging device includes an adjustable arm, an image sensor mounted on a first end of the adjustable arm and an adjustable patient positioning arm mounted on a second end of the adjustable arm. A distance between the adjustable patient positioning arm and the image sensor is adjustable based on an adjustable length of the adjustable arm. A position indicator scale of the adjustable arm includes multiple notches for calibrating the distance between the adjustable patient positioning arm and the image sensor. The adjustable patient positioning arm includes a patient teeth supporting device and a patient chin rest which are positioned at a fixed coordinate reference relative to the image sensor to capture an image of a patient's teeth. The fixed coordinate reference corresponds to co-ordinates of multiple anatomical planes associated with the patient teeth supporting device and a patient chin rest relative to the image sensor.

Abstract: This invention in one aspect relates to an acousto-mechanic sensor includes at least one inertial measurement unit (IMU) for operably detecting vibratory and motion signatures of physiological processes; and a plurality of electronic components comprising a microcontroller unit coupled to the at least one IMU for receiving data from the at least one IU and processing the received data, and a wireless communication system for wireless data transmission. The novel acousto-mechanic sensor has broad applications ranging from the assessing the efficacy of drugs for conditions that cause itch to monitoring disease severity and treatment response.

Abstract: The present disclosure relates to a body extremity temperature change monitoring system and method. More specifically, the present disclosure relates to a body extremity temperature change monitoring system and method, which can monitor a temperature change by recognizing a body extremity and measuring the body temperature of the recognized body extremity. The body extremity temperature change monitoring system comprises: an image data acquisition unit that acquires body extremity image data including a hand or a foot; a segmented area generation unit; and a body extremity temperature map generation unit that generates a body extremity temperature map using temperature data for each of the segmented areas, wherein the body extremity is defined to include base parts having a palm and a foot sole, and branch parts having fingers and toes.

Abstract: The present disclosure relates to a cervical body temperature change monitoring system and method, in which a cervical body temperature change can be monitored by measuring body temperatures of the cervical vertebra before and after treatment and analyzing the measurement results. A cervical body temperature change monitoring system may include: a cervical vertebral area processing unit that determines whether the cervical vertebra is recognized using at least one pressure sensor and performs segmentation on cervical vertebra recognition area to generate a plurality of segmented areas; a temperature distribution analysis unit that measures a body temperature in the cervical vertebra recognition area using at least one temperature sensor and generates a temperature distribution map; and a body temperature change measurement unit that derives a treatment effect by using the map.

Abstract: A method for differentiating between tissue states or types including receiving a sequence of thermal data of a tissue, wherein the sequence is sampled at at least one location of the tissue while the tissue is being thermally disturbed, deriving from the thermal data at least one tissue-related thermal variable associated with each of the tissue locations, segmenting the tissue into segments comprising the locations having corresponding the at least one thermal variable and generating an output indicating the tissue segments. The disclosure also includes a system and computer product for differentiating between tissue states or types.

Abstract: The devices and methods generally relate to vibratable sensors for measuring ambient fluid pressure, in particular implantable sensors. The devices and methods are suited to implantation within the body to monitor physiological conditions, such as portal and/or hepatic venous blood pressure, and allow frequent, remote interrogation of venous pressure. The sensor devices are relatively small compared to conventional devices for measuring fluid pressure and can be implanted in the portohepatic venous system, whereas conventional devices are too large. The small size of the device is accomplished by using a thick sensor membrane, compared to conventional devices, and by limiting the size of additional elements of the device relative to the size of the sensor membrane. The thicker sensor member also obviates the need for multiple sensor arrays and maintains the accuracy and robustness of the sensor device. A data capture, processing, and display system provides a pressure measurement reading.

Abstract: There is disclosed a blood pressure measuring device (BPMD) for obtaining an indication of a person's blood pressure via the person's finger by means of an inflatable bladder. Blood pressure may be determined without the use of any electromagnetic radiation, such as miniature dynamic light sensing (mDLS).

Abstract: A method for determining whether a signal is periodic is provided and performed by a processing device. In the method, a signal S is sampled at a time interval t to obtain (k+1) signal values S(t0+i·t), wherein i=0˜k,A 2D dot plot on an XY plane is generated, wherein the coordinates (x, y) of each point in the two-dimensional dot plot are (SPPG (10+i·t), SPPG (t0+(1+1)·t), wherein i=0˜(k?1); The degree of dispersion of the 2D dot plot is calculated. The relative relationship between the degree of dispersion and a feature of a periodic signal is determined and a determination result is generated.

Abstract: Exemplary embodiments provide an optical penile blood flow measuring technology for the monitoring of neurological and vascular function of structures at surgical risk. The measuring principle is to rely on optical absorption properties of blood components for penile blood flow monitoring. Certain embodiments use different wavelengths to measure changes in hemoglobin concentrations and are particularly advantageous in continuous, autonomous monitoring with real-time feedback to surgeons for potential intervention and decision-making in a timely manner. The measurements results can be used to provide real-time feedback to surgeons operating on the patient, or for off-line analysis and evaluation.

Abstract: A wearable device includes an attachment structure, at least one turntable operably connected to the attachment structure, and a pair of insulatively spaced-apart electrodes affixed to the at least one turntable and structured to contact a skin surface of a user. The turntable and electrodes may form parts of an electrodermal activity (EDA) sensor operably connected to the attachment structure. Use of the turntable enables a rotational orientation of the electrodes to be adjusted so as to achieve maximum available area overlap with eccrine glands located in the skin of a user in contact with the electrodes. This maximum available area overlap may provide a best available S/N ratio for an EDA signal generated based on electrode current transmission through the user's skin.

Abstract: A physical assessment system is provided that can set appropriate target values for the index of user's body and show the relationship between the index values of the user and the target values. The body assessment system (100) comprises: a body composition estimation section (54) that estimates body composition values for one or more items of the user based on the bioelectrical impedance of one or more body parts of the user; an index value acquisition section (56) that acquires the index value of the user based on one or more body composition values for an index to asses the body for a predetermined purpose; he target value acquisition section (57) that calculates target values for each user according to the physical characteristics of the user for each index; and a screen information generation section (59) that generates screen information showing the relationship between the index value and the target value.

Abstract: A method for performing patient-specific B1 field shimming in a magnetic resonance imaging system includes obtaining patient information of a patient to be imaged by the magnetic resonance imaging system. The method further includes determining an orientation of a projection based on the obtained patient information. The method also includes acquiring B1 projection data, using the magnetic resonance imaging system, along the determined orientation of the projection. In addition, the method includes determining a set of B1 shimming parameters based on the acquired B1 projection data.

Abstract: A method for patient table positioning using a patient table of a magnetic resonance device that is movable within a patient receiving area, wherein the patient table has at least two degrees of freedom with respect to its movement within the patient receiving area. Initially, the patient table is positioned within the patient receiving area in a first patient table position and first magnetic resonance data from the patient is captured. The first magnetic resonance data is used to determine a position of a region of interest and to ascertain a second patient table position, wherein in the second patient table position, the region of interest has a minimum possible distance from an isocenter. This is followed by positioning in the second patient table position, wherein at least two degrees of freedom are available to the patient table for movement into the at least one second patient table position.

Abstract: A local coil for a magnetic resonance apparatus, including: at least one antenna designed to receive radio frequency signals in a frequency and power range of a magnetic resonance measurement; a holding element designed to hold the at least one antenna in a position that is appropriate for application on a diagnostically relevant body region of a patient, wherein the at least one antenna is mechanically connected to the holding element; a base element, wherein a first end of the holding element is mechanically connected to the base element and wherein a second end of the holding element opposite the first end is free-floating; and a guide system that is mechanically connected to the base element and the holding element, and is designed to position the holding element variably with respect to the base element.

Abstract: Apparatus, systems, and methods are provided for localizing lesions within a patient's body, e.g., within a breast. The system may include one or more markers implantable within or around the target tissue region, and a probe for transmitting and receiving electromagnetic signals to detect the one or more markers. During use, the marker(s) are into a target tissue region, and the probe is placed against the patient's skin to detect and localize the marker(s). A tissue specimen, including the lesion and the marker(s), is then removed from the target tissue region based at least in part on the localization information from the probe.

Abstract: Various embodiments are described herein for a device, system, and method for identifying a location of an ingestible device within a gastrointestinal tract of a body. In some embodiments, the ingestible device includes a sensing unit with an axial optical sensing sub-unit located proximal to at least one end of the device, and a radial optical sensing sub-unit located proximal to a radial wall of the device, and may autonomously identify a location within the gastrointestinal tract. In some embodiments, the ingestible device includes optical illumination sources and detectors that operate at a plurality of different wavelengths, and may discern regions of a gastrointestinal tract by using the reflection properties of organ tissue and occasional particulates. In some embodiments, the ingestible device may sample fluid or release medicament based on a detected device location.

Abstract: Electric equipment includes: a command input unit to which a switching command is input contactlessly from an outside; and a mode switcher to switch an electric circuit between a normal operation mode and a sleep mode in response to the switching command. The normal operation mode includes the normal operation mode in an unlocked state and the normal operation mode in a locked state in which switching to the sleep mode is prohibited. The switching command includes: a first switching command for switching to the sleep mode, a second switching command for switching to the normal operation mode in the unlocked state, and a third switching command for switching to the normal operation mode in the locked state, having a longer input time than the second switching command. The switching command uses magnetism, light, or a sound wave as a carrier. The command input unit includes a carrier detection sensor.

Abstract: A wireless circuit includes a housing, such as a hermetic housing, and at least one antenna coil wound about a coil axis within the housing. The coil axis may be substantially parallel to at least one wall of the housing, wherein the wall parallel to the coil axis is substantially thinner than other walls of the housing.

Abstract: In some examples, a capnography filtration device includes a housing, a filter member, and a gas-permeable hydrophobic barrier. The housing may define a housing lumen extending from a first housing end to a second housing end. The filter member may be positioned within the housing and extend at least partially along the housing lumen. The filter member may include a hydrophilic material defining a filter lumen configured to receive exhalation introduced into the capnography filtration device. The gas-permeable hydrophobic barrier may be positioned within the housing lumen and configured to allow passage of dry gases from the exhalation through an outlet of the capnography filtration device and resist passage of moisture and liquid. In some examples, a method includes introducing exhalation from a patient into the device, absorbing moisture and liquid from the exhalation into the filter member, and flowing dried exhalation from the device to a capnography monitor.

Abstract: A body shape analysis device, includes a model storage unit to store three-dimensional homologous models for body shapes with a three-dimensional coordinate group indicating an anatomical feature of a body, a measurement data acquirer to acquire, as measurement data, a three-dimensional coordinate group indicating an anatomical feature corresponding to the three-dimensional homologous model of a body shape of a measurement subject, and an evaluation determination unit to determine, among the three-dimensional homologous models, a three-dimensional homologous model similar to a body shape of the measurement subject by evaluating similarity in coordinates between a three-dimensional coordinate group indicating an anatomical feature in the measurement data and a three-dimensional coordinate group indicating an anatomical feature in each of the three-dimensional homologous models.

Abstract: Systems and methods for prompting a user to perform an exercise and monitoring the exercise are provided. Multiple independent sensors or sensor systems may be used to calculate energy expenditure. Various criteria may be used to manually or automatically select the independent sensor or sensor system or combination that will be used with the energy expenditure calculations.

Abstract: Neuromuscular monitoring is described that uses a novel lead assembly and a monitor that can select the appropriate electrodes on the lead assembly and calibrate the stimulation signals applied to the patient through the lead assembly. The monitoring can also set a noise floor value to reduce the likelihood of an erroneous train of four ratio.

Abstract: An insertion needle structure includes a needle sharp and a needle body. The needle body is integrally connected to the needle sharp and has a receiving space for receiving the biosensor. The needle body includes a base wall, two side walls, two slope sections and two curved connecting sections. The side walls are located at two sides of the base wall, respectively, the side walls are at least partially nonparallel, and each of the side walls is at least partially flat. Each of the slope sections is connected between each of the side walls and the needle sharp, and each of the slope sections is curved. Each of the curved connecting sections is connected between each of the side walls and the base wall and between each of the slope sections and the base wall. The needle sharp extends from the base wall and the curved connecting sections.

Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.

Abstract: A device includes a glucose monitor comprising at least one sensor electrode configured to sense signals indicative of interstitial glucose level of a patient. The device also includes a memory and one or more processors implemented in circuitry and in communication with the memory. The one or more processors are configured to cause delivery of a cleaning electrical current to the at least one sensor electrode. The cleaning electrical current is one or more electrochemical cleaning pulses configured to at least partially remove, in vivo and from the sensor electrode, excipients associated with the delivery of a fluid that includes insulin.

Abstract: Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes at least one light source configured to strike a target area of a sample, at least one light detector positioned to receive light from the at least one light source and to generate an output signal, having a time dependent current, which is indicative of the power of light detected, a processor configured to receive the output signal from the at least one light detector based on the received output signal, calculate the attenuance attributable to blood in a sample present in the target area with a ratio factor, eliminate effect of uncertainty caused by temperature dependent detector response of the at least one light detector, and then determine a blood glucose level associated with a sample present in the target area based on the calculated attenuance with the processor.

Abstract: A medical system comprising: an analyte sensor for receiving an analyte signal corresponding to an analyte concentration of a user; a health monitor device comprising a display unit and in communication with the analyte sensor, the health monitor device comprising a processor and memory communicably coupled to the processor, the memory including instructions stored therein that, when executed by the processor, cause the processor to: receive the analyte signal from the analyte sensor; determine the analyte concentration based on the analyte signal; calculate a recommended medication dosage based on the analyte concentration; associate a current parameter type with the recommended medication dosage; associate the current parameter type to at least one corresponding stored historical parameter type associated with a historical medication dosage; and display, on the display unit, the recommended medication dosage and the historical medication dosage.

Abstract: Provided is a continuous blood glucose measurement body attachment unit, which is manufactured in an assembled state in an applicator to minimize separate additional operations, such that the body attachment unit can be attached to the body with only a simple operation of the applicator and, particularly, the body attachment unit has a wireless communication chip to be capable of communicating with an external terminal, thereby enabling simple and convenient usage without an additional operation in which a separate transmitter must be connected and enabling maintenance to be more easily performed, and after the body attachment unit is attached to the body, an operation starts by the control of a user, such that an operation start time point can be adjusted to an appropriate time point according to the needs of the user, and an operation can start in a stabilized state, such that blood glucose can be accurately measured.

Abstract: Provided is a continuous blood glucose measurement body attachment unit, which is manufactured in an assembled state in an applicator to minimize separate additional operations, such that the body attachment unit can be attached to the body with only a simple operation of the applicator and, particularly, the body attachment unit has a wireless communication chip to be capable of communicating with an external terminal, thereby enabling simple and convenient usage without an additional operation in which a separate transmitter must be connected and enabling maintenance to be more easily performed, and after the body attachment unit is attached to the body, an operation starts by the control of a user, such that an operation start time point can be adjusted to an appropriate time point according to the needs of the user, and an operation can start in a stabilized state, such that blood glucose can be accurately measured.

Abstract: A surgical elevator has an oximeter sensor at its tip, which allows measuring of oxygen saturation of a tissue.

Abstract: An assembly for delivering an analyte sensor comprising a sensor control device. The sensor control device comprises an electronics housing with a shell having a first aperture and a first interface, and a mount having a second aperture and second interface, wherein the housing has an interior space. The two interfaces define a first sterile barrier. The housing also comprises a first mating member, a circuit board, and an analyte sensor. The assembly also comprises an applicator to deliver the sensor, and comprising a housing and a cap removably coupled to the housing to seal the applicator's interior, a sharp hub, and a second mating member extending within the first or second aperture, which mates with the first mating member to define a second sterile barrier. The sensor control device also comprises a collimator, a third sterile barrier, and a fourth sterile barrier which define a sterilization zone.

Abstract: Overlapping data streams and sensor transitions is described. In accordance with the described techniques, a first data stream of first analyte measurements is received, at a computing device and during an overlap period, from a first analyte sensor worn by a user and a second data stream of second analyte measurements is received, at the computing device and during the overlap period, from a second analyte sensor worn by the user. The first data stream and the second data stream are received concurrently during the overlap period. A combined analyte measurement is generated based on the first analyte measurements and the second analyte measurements. In one or more implementations, the combined analyte measurement is generated as a weighted average of the first analyte measurements and the second analyte measurements. The combined analyte measurement is then output on a display of the computing device.

Abstract: A device for detecting or identifying diseases or disorders in a human subject by collecting biological sample from the human subject comprises a pump unit, a first unit, a second unit, a gas permeable filter, and a collector. The first unit comprises a first chamber and a gas sensor unit. The second unit comprises a second chamber, an outlet portion and an inlet portion. The gas permeable filter is disposed in an upstream region of the second chamber. The collector is disposed in a downstream region of the second chamber. The pump unit is configured, when activated, to create a negative pressure in a gas flow pathway provided between the first chamber and second chamber through the outlet portion, thereby allowing an ambient gas stream forcedly flows from an exterior through the inlet portion into the second chamber and the first chamber.

Abstract: In some examples, a kit includes a pulse oximetry sensor patch and a stretchable pressure backing configured to be applied to a region of a patient's skin. An assembly may include the stretchable pressure backing securing the pulse oximetry sensor patch against the patient's skin. The stretchable pressure backing is configured to stretch across the pulse oximetry sensor patch from an unstretched length to a stretched length. When in its stretched length, the stretchable pressure backing is configured to press the pulse oximetry sensor patch against the patient's skin to apply pressure to reduce venous pulsations in the region of the patient's skin. An example technique includes applying the pulse oximetry sensor patch to the patient's skin and stretching the stretchable pressure backing across the pulse oximetry sensor patch to its stretched length to apply pressure to the pulse oximetry sensor patch to reduce venous pulsations.

Abstract: A biometric measurement device including a photodiode array having a number of photodiodes and at least one polarization filter covering at least one of the photodiodes. The biometric measurement device also includes a light-emitting diode array having a number of light-emitting diodes proximate to the photodiode array, a non-volatile memory device, and a processor in electronic communication with the non-volatile memory device. The photodiode array is configured to receive a reflected waveform from light emitted from the light-emitting diode array, and the processor is configured to determine at least one physiological parameter based on a pulsatile (AC) component and a static (DC) component of the reflected waveform. The light-emitting diodes may emit polarized light.

Abstract: The present disclosure provides analyte sensors comprising a sensor tail substrate having a lower portion and configured for insertion into a tissue; a first working electrode disposed on the lower portion of the sensor tail substrate; a first sensing layer disposed upon a surface of the first working electrode; and a membrane disposed over at least the sensing layer; wherein the membrane comprises 20% to 50% by weight of a silver salt. The present disclosure also provides methods of using such analyte sensors for detecting one or more analytes present in a biological sample and methods of manufacturing the analyte sensors.

Abstract: Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.

Abstract: Provided herein is a blood draw device including a housing defining a housing lumen and an inner volume proximal to the housing lumen, a coupling device, a catheter tube movably received within the housing, and an advancement member movable relative to the housing to move the catheter tube between a first position where the catheter tube is disposed within the housing and a second position where a distal end of the catheter tube is disposed beyond the distal end of the housing. A first port is provided on the housing, in fluid communication with the housing lumen, and a second port is provided proximally from the housing, in fluid communication with the catheter tube. A seal is positioned in the housing lumen proximal to the first port, with the catheter tube proximal to the seal when in the first position and extending through the seal when in the second position.

Abstract: Provided herein is an instrument delivery device including an instrument, a housing having a proximal end and a distal end and defining an inner volume configured to movably receive the instrument, a coupling device positioned at the distal end of the housing and including a lock configured to couple the housing to a proximal connector of the catheter assembly, and an advancement member configured to move relative to the housing to move the instrument between a first position and a second position. A scrubbing cap is engaged with the lock that includes a scrubbing insert, a housing having a connector portion configured to engage with the lock, a holder portion configured to retain the scrubbing insert therein, and a seal that seals the scrubbing insert within the holder portion. The scrubbing cap is engaged with the lock so as to be removable from the instrument delivery device.

Abstract: Provided herein is a system including a container assembly having a cap and defining a reservoir, and a fluid access assembly having a housing defining an interior, a fluid access component, and a fluid connector component, the housing having a distal end and a proximal end, the fluid access component extending from the housing distal end into the interior of the housing, the fluid access component defining a lumen, the fluid connector component disposed on the distal end of the housing. A scrubbing cap is provided at or adjacent a distal end of the fluid access assembly, with the scrubbing cap having a scrubbing insert and a housing defining a cavity configured to retain the scrubbing insert therein.

Abstract: Exemplary embodiments include a sample collection device having a tube with an inner seal producing a sequestered lower compartment. In certain embodiments, the sequestered compartment may have a stabilizing reagent. The device may also have a cap suited towards the sample type being stored in the tube. In some cases, the cap may pierce the inner seal to allow a liquid sample to mix with the stabilizing reagent. In the case of liquid samples, a funnel may be used to aid in the deposition of the sample. In other cases, a swab or similar collection tool can be inserted into the tube, piercing the inner seal, and the cap will retain the swab in the cap. The device can be used for the collection of saliva, swab, or other samples at home without clinical supervision. The samples can be transported and stored for further analysis of the sample for DNA, RNA, or other biological components.