Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.

Abstract: Method of preparing a keratin-based biomaterial is provided. The method comprises a) reacting keratin with a polymer having at least one of an amine and carboxylic functional group in the presence of a carbodiimide cross-linking agent to form a cross-linked keratin-polymer material; and b) freeze drying the cross-linked keratin-polymer material to form the keratin-based bio-material. A keratin-based biomaterial thus prepared is also provided.

Abstract: The present invention is directed to a fully biodegradable material based on a plant protein. The present invention is also directed to a process method of making a gluten-based biodegradable material by a water induced flocculation step. A fully hydrated gluten dough with or without an additive or/and a filler formed from the flocculation step, which has low viscoelasticity, is further molded into an article with desired shapes under a low shear stress in a relatively low temperature range. A rigid or flexible biodegradable plastic article is obtained by removing extra water at a temperature lower than decomposition temperature of the gluten.

Abstract: Disclosed herein are matrices for isolating a biological macromolecule from a biological sample, the matrix comprising: a biopolymer capable of binding to the biological macromolecule, wherein the biopolymer is about 0% to about 10% dissolvable in water at a pH of about 6 to about 8 and at ambient temperature but is about 10% to 100% dissolvable in a chaotropic solvent or an organic solvent, and wherein the biopolymer is not squid ring teeth protein; and a surfactant, excipient, or combination thereof. Also provided are methods of using, and kits comprising, the matrices. The disclosed matrices aid in collecting and releasing near quantitative amounts of a biological macromolecule from a biological and/or test sample.

Abstract: The disclosure relates to a milk protein hydrol gel, in which at least one protein which is obtained from milk and which can be thermally plasticized, is plasticized using a plasticizing agent, such as for example, water or glycerol at temperatures between room temperature and preferably up to 140° C. by means of mechanical stress and subsequently retreated according to a continuous or discontinuous process to form hydrogels.

Abstract: A plastic molding composition includes a raw powder, gelatin, a polar solvent, and a plasticizer. The raw powder contains at least one of a ceramic particle and a metal particle. The plasticizer reduces the minimum amount of the solvent necessary to give flowability to the composition. The plasticizer is a water-soluble or water-dispersible compound. The plasticizer has a ratio of hydroxyl number to carbon number per molecule in a range from 8% to 100%. The plasticizer is in solid or liquid form. When the plasticizer is in liquid form, the plasticizer has volatility equal to or lower than volatility of water.

Abstract: This invention relates to methods and compositions for preparation of silk-PEGs based biomaterials through crosslinking by chemically reacting active polyethylene glycols (PEGs) possessing different chemical groups (e.g., thiols and maleimides functionalized PEGs) that are additionally stabilized by the beta-sheet formation of silk fibroin. The crosslinked silk-PEGs biomaterials present strong adhesive properties, which are comparable to or better than the current leading PEG-based sealant, depending on the silk concentration in the silk-PEGs biomaterials. In addition, the silk-PEGs based biomaterials are cytocompatible, show decreased swelling behavior and longer degradation times, which make them suitable for hemostatic applications where the current available tissue sealant products can be contraindicated.

Abstract: A composition suitable for making films, wherein the composition contains keratin obtained from avian feathers and at least one OH containing plasticizer. Protein-based films containing at least one protein and at least one OH containing plasticizer, wherein the protein is a protein whose PE value is ?2.5 where PE=(S+T+Y)/C where PE is plasticizer efficiency and where S, T, Y, and C are the amino acids serine, threonine, tyrosine, and cysteine, respectively, in the protein. Preferably the protein is keratin obtained from avian feathers.

Abstract: A non-toxic paint and methods for making same are disclosed herein, such paint being comprised of a vehicle, a kaolin slurry and a pigment dispersion. Specifically, the vehicle is comprised of casein protein and potassium sorbate. Such paints are non-toxic and have a substantially long wet-shelf life.

Abstract: A nongermicidal composition which comprises an aqueous solution of an organic polymer, wherein the solution when applied to a substrate prevents the growth of microorganisms.