Aminopolysaccharide (e.g, Heparin, Glycosamine, Mucopolysaccharide, Chitin, Hyaluronic Acid, Etc.) Patents (Class 106/162.2)
  • Patent number: 11220603
    Abstract: The invention relates to a silicate coating containing (A) at least one compound of the formula (I), where R1 represents H, C1-C4-alkyl, CH2CH2OH, or CH2CH(CH3)OH, (B) at least one silicate binder, (C) if appropriate, one or more polymer binders, (D) if appropriate, further additives usual for the production of silica coatings, and (E) water.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: January 11, 2022
    Assignee: Clariant International Ltd.
    Inventors: Rainer Kupfer, Jesús Pitarch López, Christoph Söffing, Jörg Rüger
  • Patent number: 11067514
    Abstract: A sensor has a transparent polymer aerogel, and sensing materials dispersed into the transparent, polymer aerogel, where the sensing materials change color in response to environmental conditions. A method of forming a sensor includes providing a substrate, forming a polymer aerogel layer on the substrate, and infusing the polymer aerogel layer with sensing molecules.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: July 20, 2021
    Assignees: PALO ALTO RESEARCH CENTER INCORPORATED, XEROX CORPORATION
    Inventors: Gabriel Iftime, Jessica Louis Baker Rivest, George A. Gibson, Eric Cocker, Mahati Chintapalli, Quentin Van Overmeere
  • Patent number: 10850003
    Abstract: A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: December 1, 2020
    Assignee: Cresilon, Inc.
    Inventor: Joseph A. Landolina
  • Patent number: 10260151
    Abstract: Provided are a treatment liquid for a trivalent chromium conversion coating, achieving excellent corrosion resistance and scratch resistance without containing a cobalt compound, with high stability and adequate consideration for environmental issues; and a method for treating a metal substrate using the same. Provided is a treatment liquid for a trivalent chromium conversion coating on the surface of a metal substrate comprising: a trivalent chromium compound; titanium lactate; one or more compounds of transition metal other than cobalt; two or more organic acids or organic acid salts, and at least one ion species selected from chloride ions, nitrate ions, and sulfate ions; but no cobalt compound.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: April 16, 2019
    Assignee: Nippon Hyomen Kagaku Kabushiki Kaisha
    Inventors: Kazuyuki Shinozaki, Mitsuomi Katori, Hiroyuki Kaneta
  • Patent number: 10214596
    Abstract: A process for producing chitin nanocrystals (ChNCs) involves contacting a chitinous material with a sufficient amount of an inorganic persulfate to produce chitin nanocrystals from the chitinous material. The process permits one-spot production of ChNCs from biomasses such as crustaceans, fungi, mushrooms, insects or mixtures thereof. Chitin nanocrystals produced by the process comprise surface carboxylic groups and are not initially deacetylated.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: February 26, 2019
    Inventors: John H. Luong, Edmond Lam, Chi Woon Leung, Sabahudin Hrapovic, Keith B. Male
  • Patent number: 10010650
    Abstract: Disclosed is a composite hemocompatible material and a method for producing a composite hemocompatible material. The composite material includes a synthetic substrate and an animal biological tissue. The animal biological tissue is interlinked the synthetic substrate so as to bond the animal biological tissue to the synthetic substrate and form the composite hemocompatible material.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: July 3, 2018
    Assignee: Carmat
    Inventors: Antoine Capel, Alain Carpentier, Marion Melot
  • Patent number: 9272069
    Abstract: Described herein is the synthesis of adhesive complex coacervates. The adhesive complex coacervates are composed of a mixture of one or more polycations, one or more polyanions, and one of more multivalent cations. The polycations and polyanions in the adhesice complex coacervate are crosslinked with one another by covalent bonds upon curing. The adhesive complex coacervates have several desirable features when compared to conventional bioadhesives, which are effective in water-based applicatgions. The adhesive complex coacervates described herein exhibit good interfacial tension in water when applied to a substrate (i.e., they spread over the interface rather than being beaded up). Additionally, the ability of the complex coacervate to crosslink intermolecularly increases the cohesive strength of the adhesive complex coacervate. The adhesive complex coacervates have numerous biological applications as bioadhesives and drug delivery devices.
    Type: Grant
    Filed: November 13, 2008
    Date of Patent: March 1, 2016
    Assignee: University of Utah Research Foundation
    Inventors: Russell Stewart, Hui Shao
  • Patent number: 9076999
    Abstract: A laminating water-based surface treatment agent according to the present invention includes a chitosan derivative, a carboxyl compound having at least one carboxyl group in a molecule, and water. The content mass ratio of the chitosan derivative/the carboxyl compound falls within a range of 1.0/0.5 to 1.0/3.0. The laminating water-based surface treatment agent of the present invention can form an undercoating excellent in HF-resistance, electrolyte resistance, and solvent resistance, and also can sufficiently secure laminating adherence for a long term under more extreme environments required for a packaging material for a battery case or a tab lead for, e.g., a lithium ion secondary battery for automobiles.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: July 7, 2015
    Assignee: Showa Denko Packaging Co., Ltd.
    Inventors: Daisuke Hashimoto, Takurou Watanabe
  • Publication number: 20150148909
    Abstract: A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.
    Type: Application
    Filed: August 18, 2014
    Publication date: May 28, 2015
    Inventors: Peter F. Sharkey, Charles F. Leinberry
  • Patent number: 9023143
    Abstract: A cast ceiling tile and method for manufacture incorporates chitosan in an amount sufficient to provide improved strength.
    Type: Grant
    Filed: December 28, 2011
    Date of Patent: May 5, 2015
    Assignee: USG Interiors, LLC
    Inventor: Enrique L. Albarran
  • Patent number: 9017469
    Abstract: It is an object of the present invention to provide a spinning solution for industrial production of pure chitosan fiber and the method for fabricating the same. The method comprises the steps of: step (a): screening a flake chitosan raw material and removing impurities; step (b): putting in a dissolving kettle the screened flake chitosan raw material with a weight which is 3%-8% of the total weight of the spinning solution, sealing the dissolving kettle, and evacuating into vacuum; step (c): adding 0.9%-6% acetic acid solution, and soaking at the room temperature for 40-60 minutes; step (d): uniformly stirring at a rate of 26-60 rpm for 7.5-19 hours under a pressure of ?5000 pa in the dissolving kettle, standing for 1-3 hours, and obtaining a spinning solution.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: April 28, 2015
    Assignee: Shandong Huaxing Haici New Materials Co., Ltd
    Inventors: Jiacun Zhou, Guangmin Hu
  • Publication number: 20150108410
    Abstract: Binder including (i) a chitosan derivative and (ii) deionized water or 1 vol. % aqueous solution of acetic acid as a dispersant. A method for preparing an electrode of a lithium ion battery by adding the binder to a conductive agent.
    Type: Application
    Filed: December 23, 2014
    Publication date: April 23, 2015
    Inventors: Lingzhi ZHANG, Lu YUE, Haoxiang ZHONG
  • Patent number: 8961675
    Abstract: An acoustic building material and method for manufacture incorporates chitosan in an amount sufficient to achieve acceptable physical properties with a reduction in binder and to allow the postindustrial/postconsumer content of the building material to be increased. The chitosan also enhances the dewatering of the building material.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: February 24, 2015
    Assignee: USG Interiors, LLC
    Inventor: Enrique L. Albarran
  • Publication number: 20150000561
    Abstract: The invention relates to a new hyaluronan derivative according to the general formula (I), the method of preparation thereof, a hydrogel based on the new derivative, method of preparation of the hydrogel and the use of the hydrogel in tissue engineering, cosmetics, medicine or regenerative medicine, especially in the form of scaffolds for the treatment of articular cartilage or bone tissue defects.
    Type: Application
    Filed: February 26, 2013
    Publication date: January 1, 2015
    Inventors: Lucie Wolfova, Martin Pravda, Marcela Foglarova, Miroslava Nemcova, Krzysztof Niedoba, Vladimir Velebny
  • Patent number: 8906881
    Abstract: Chitosan-based nail formulations are useful to treat nail inflammatory diseases like psoriasis, atopic dermatitis and lichen planus. The chitosan is normally in the form of an amino-polysaccharide derivative, preferably water soluble, such as hydroxypropyl chitosan. The formulation may be a nail lacquer, a spray, a cream, an ointment, a gel, a lotion or a foam and may have a content in chitosan, chitosan derivative or a salt thereof from 0.1 to 25 wt. % with respect to the total weight of the formulation.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: December 9, 2014
    Assignee: Polichem SA
    Inventor: Federico Mailland
  • Publication number: 20140331894
    Abstract: The present invention provides a method for preparing a water insoluble gel composition comprising: mixing a water soluble polysaccharide, an epoxy cross-linking agent, an alkaline compound and a solvent; and drying the thus obtained mixture at 1 to 30° C. under vacuum to remove the solvent, and a water insoluble gel composition.
    Type: Application
    Filed: November 21, 2012
    Publication date: November 13, 2014
    Applicant: AMOREPACIFIC CORPORATION
    Inventors: Young Chang Ah, Sung Yeon Cho, In Seok Hwang, Sun Young Park, Hyun Ju Ko, Hyuk Kim, Min Jung Kwon, Won Seok Park
  • Patent number: 8877170
    Abstract: The present disclosure relates to implantable medical devices having a non-bioabsorbable substrate and an amphiphilic coating covalently bonded to the substrate for reducing the inflammatory response to the device after implantation.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: November 4, 2014
    Assignee: Sofradim Production
    Inventors: Sebastien Ladet, Philippe Gravagna
  • Publication number: 20140289986
    Abstract: A cotton bud with a rod-like grip body and with a bud body that is arranged at least at one free end of the grip body. The rod-like grip body is a biologically degradable extrusion body, and includes natural fibres embedded into a material matrix.
    Type: Application
    Filed: June 20, 2012
    Publication date: October 2, 2014
    Applicant: ROWEG HOLDING AG
    Inventors: Beat Hani, Christian Rytka, Guy Petignat
  • Publication number: 20140294770
    Abstract: The present invention features, inter alia, biocompatible compositions that include a poloxamer and one or more additives such as hyaluronic acid, gelatin, fibronectin, or a peptide fragment of fibronectin. The compositions are useful in tissue repair or remodeling, including repair of an injured spinal disc, in drug delivery, in cell culture, and in inhibiting the formation of adhesions.
    Type: Application
    Filed: July 5, 2012
    Publication date: October 2, 2014
    Applicant: The Research Foundation of State University of New York
    Inventors: Raphael Davis, Divya Bhatnagar, Miriam Rafailovich
  • Publication number: 20140287061
    Abstract: A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.
    Type: Application
    Filed: November 12, 2012
    Publication date: September 25, 2014
    Applicant: Suneris, Inc.
    Inventor: Joseph A. Landolina
  • Publication number: 20140242870
    Abstract: The present invention relates to a composite including chitosan and/or chitin and a catechol-based compound, an organic reinforcing material composition including the composite, a product manufactured by using the organic reinforcing material composition, and a method for preparing a chitosan and/or chitin composite with improved strength, including the step of adding the catechol-based compound to chitosan and/or chitin. The chitosan and/or chitin composite including the catechol-based compound is advantageous in that it is able to maintain high strength in a wet-swollen state by improving the problem of strength reduction due to moisture, compared to the composites containing no catechol-based compound.
    Type: Application
    Filed: September 27, 2012
    Publication date: August 28, 2014
    Inventors: Dong Soo Hwang, Dong Yeop Oh, Sang Sik Kim, Hyung Joon Cha
  • Publication number: 20140238267
    Abstract: The present invention relates to a method of manufacturing soil reinforced by microbe-based bio-binders and soil produced by the method. The bio-binders are not harmful to humans, do not cause environmental pollution and secure sufficiently the soil strength and resistance against wind. According to the method, the soil is prepared by binding sand whose major components are silica and alumina, ureolytic microbes, urea, calcium ion, and polymer fibers, and the content of polymer fibers in sand ranges from 0.05 wt % to 5 wt %. In addition, it is preferable that the microbes provide CaCO3 at a rate at 1˜7×10?9 g CaCO3 ppt cell?1 hr?1 under optimum conditions.
    Type: Application
    Filed: November 10, 2011
    Publication date: August 28, 2014
    Applicants: LOTTE ENGINEERING & CONSTRUCTION, SOUTH DAKOTA SCHOOL OF MINES AND TECHNOLOGY, ECHO PHILE
    Inventors: Sang Chul Bang, Sookie S. Bang, Seong Rok Choi, Seok Jin Lee, Joo Ho Lee, Jong Sun Kim
  • Publication number: 20140242146
    Abstract: The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.
    Type: Application
    Filed: May 5, 2014
    Publication date: August 28, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON I
    Inventors: Alain DOMARD, Laurent DAVID, Florence DUPASQUIER
  • Publication number: 20140205838
    Abstract: Hydroxyl polymer-containing compositions, especially hydroxyl polymer-containing compositions that can be processed into polymeric structures, especially polymeric structures in the form of fibers are provided.
    Type: Application
    Filed: March 26, 2014
    Publication date: July 24, 2014
    Applicant: The Procter & Gamble Company
    Inventors: Paul Arlen FORSHEY, Gregory Charles GORDON, Larry Neil MACKEY, Mark Ryan RICHARDS
  • Publication number: 20140190367
    Abstract: This invention concerns a biopolymer consisting of a polysaccharide composed of galactose (50-90%), glucose (1-25%), mannose (1-25%) and rhamnose (0.5-20%), which may additionally contain, in trace amounts, xylose, fucose, ribose, arabinose and/or fructose. The galactose-rich polymer also contains non-saccharide components, namely, acyl groups. This invention also concerns a process for the production of the galactose-rich polymer, by microbial fermentation using glycerol or glycerol-rich substrates as carbon source, and recovery of the polymer from the culture broth. From the process for the production of the galactose-rich polymer results the co-production of intracellular biopolymers, namely, polyhydroxyalkanoates.
    Type: Application
    Filed: March 5, 2014
    Publication date: July 10, 2014
    Applicant: 73100- SETENTA E TRES MIL E CEM, LDA.
    Inventors: Maria d'Ascencao Carvalho Fernandes De Miranda Reis, Rui Manuel Freitas Oliveira, Cristina Paula Pereira Da Cunha Rodrigues Oliveira, Maria Filomena Andrade De Freitas, Victor Manuel Delgado Alves, Joana Oliveira Pais
  • Patent number: 8747539
    Abstract: There is provided an adhesive comprising chitosan an optionally a crosslinking agent. A method for preparing such an adhesive is also disclosed. A wood-panel made with such an adhesive is also provided. Moreover, a method for manufacturing a wood-based panel is provided. The method comprises preparing a mixture comprising wood, chitosan, optionally a crosslinking agent, and optionally an acid, forming a mat with the mixture, and pressing the mat under heat and pressure so as to obtain the wood-based panel.
    Type: Grant
    Filed: May 3, 2012
    Date of Patent: June 10, 2014
    Assignees: Uniboard Canada Inc., EXP Services Inc.
    Inventors: Andre Verville, Yves Charest, Martin Beaulieu, Stephane Chabot, Richard Lepine
  • Publication number: 20140142190
    Abstract: Biodegradable single-phase cohesive hydrogels useful, e.g., for the formulation of viscosupplementation compositions or compositions for filling wrinkles, contain a homogeneous blend of x polymers, which may be identical or different, crosslinked prior to the interpenetration thereof by mixing in the form of a single-phase hydrogel, wherein such crosslinked polymers are insoluble in water and miscible with one another, and x ranges from 2 to 5; in one embodiment, the hydrogels are such that the x polymers have identical or different degrees of crosslinking, at least one of the x polymers having a degree of crosslinking x1 and at least one of the x polymers having a degree of crosslinking x2, with x1 being greater than or equal to x2.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: Laboratoires Vivacy
    Inventors: Estelle Marie Piron, Guy Vitally
  • Patent number: 8703924
    Abstract: This invention relates to a cross-linkable chitosan composition comprising chitosan having a degree of deacetylation between 30 and 75%, wherein the chitosan is randomly deacetylated, and a cross-linking agent, wherein the molar ratio of the cross-linking agent to chitosan is 0.2:1 or less based on the number of functional groups in the cross-linking agent and the number of accessible amino groups in the chitosan. The invention also provides a chitosan hydrogel formed therefrom and uses thereof.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: April 22, 2014
    Assignee: Viscogel, AB
    Inventor: Mats Andersson
  • Publication number: 20140100436
    Abstract: An electrode sensor kit for establishing electrical contact with skin comprises at least one contact element and a preparation comprising a mixture of water and at least one lipid for enhancing electrical contact properties between said contact element and the skin, wherein said mixture forms an emulsion, in particular a water-in-oil or an oil-in-water emulsion, having a conductivity of less than 3 mS/cm. An electrode assembly for electrical impedance tomography which comprises said kit is characterized in that (a) said at least one contact element forms an electrode or sensor plate, and (b) said at least one contact element comprises a layer of said preparation.
    Type: Application
    Filed: June 7, 2012
    Publication date: April 10, 2014
    Applicant: SWISSTOM AG
    Inventors: Josef X. Brunner, Stephan Bohm
  • Patent number: 8679437
    Abstract: The present application discloses a process for preparing silica particles, said process comprising the step of mixing (I) an aqueous phase and (II) an oily phase comprising pre-polymerized tetraalkoxy orthosilicate, one or more alcohols, and optionally one or more polyalkylene glycols, wherein said aqueous phase comprises, in an aqueous solvent, one or more C6-30-alkyl modified polysaccharides, and optionally one or more polyalkylene glycols.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: March 25, 2014
    Assignee: FEF Chemicals A/S
    Inventor: Thomas Everdahl
  • Publication number: 20140013998
    Abstract: Enzymatically degradable compositions containing biocompatible polymers reactive with glycosaminoglycan compositions having a first glycosaminoglycan compound having a first degree of acetylation and a second glycosaminoglycan compound having a second degree acetylation different than the first degree of acetylation.
    Type: Application
    Filed: March 23, 2012
    Publication date: January 16, 2014
    Applicant: Sofradim Production
    Inventor: Sébastien Ladet
  • Publication number: 20130320271
    Abstract: This invention relates to a coating formulation for manufacturing an electrode plate, which contains a solution of a hydroxyalkylchitosan and an organic acid and/or its derivative in an aprotic polar solvent, and an active material added to the solution and kneaded with the solution, the electrode plate, a manufacturing process of the electrode plate, a battery, a capacitor, and an undercoating formulation. According to this invention, a coating formulation for manufacturing an electrode plate for a nonaqueous electrolyte secondary battery or an electrode plate for an electric double layer capacitor having excellent adhesion and improved contact resistance between an active material layer and a collector, the electrode plate, its manufacturing process, the battery and the capacitor can be provided.
    Type: Application
    Filed: August 5, 2013
    Publication date: December 5, 2013
    Applicants: Dainichiseika Color & Chemicals Mfg. Co., Ltd., Kyoritsu Chemical & Co., Ltd.
    Inventors: Satoshi YAMAZAKI, Takaya Sato, Takanori Sannan, Nobuyuki Kobayashi, Shinya Tsuchida
  • Publication number: 20130276669
    Abstract: An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N-acylchitosan hydrogel.
    Type: Application
    Filed: March 26, 2013
    Publication date: October 24, 2013
    Inventor: Thomas Freier
  • Publication number: 20130280593
    Abstract: A laminating water-based surface treatment agent according to the present invention includes a chitosan derivative, a carboxyl compound having at least one carboxyl group in a molecule, and water. The content mass ratio of the chitosan derivative/the carboxyl compound falls within a range of 1.0/0.5 to 1.0/3.0. The laminating water-based surface treatment agent of the present invention can form an undercoating excellent in HF-resistance, electrolyte resistance, and solvent resistance, and also can sufficiently secure laminating adherence for a long term under more extreme environments required for a packaging material for a battery case or a tab lead for, e.g., a lithium ion secondary battery for automobiles.
    Type: Application
    Filed: April 23, 2013
    Publication date: October 24, 2013
    Applicant: SHOWA DENKO K.K.
    Inventors: Daisuke HASHIMOTO, Takurou WATANABE
  • Patent number: 8496748
    Abstract: The invention relates to a polymer composition formed from a biologically degradable polymer and a material from sea plants and/or shells of sea animals or at least two components selected from the group consisting of saccharides and the derivatives thereof, proteins, amino acids, vitamins and metal ions. The invention additionally relates to a molded article formed from the polymer composition. The molded article may be packaging material or fibrous material, in the form of fibrous material as a mixing component for the production of yarns, and in the form of fibrous material for the production of nonwoven fabrics or woven fabrics.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: July 30, 2013
    Assignee: Smartfiber AG
    Inventors: Stefan Zikeli, Thomas Endl, Michael Gert Martl
  • Patent number: 8465582
    Abstract: The present invention relates to a process of using a heat responsive mixture to produce inorganic interconnected 3D open-cell bone substitutes which can be applied in the orthopedic or dental field for treatment of bone damage. The invention provides a simple and easily-controlled process of preparing porous inorganic bone substitute materials.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: June 18, 2013
    Assignee: Taipei Medical University
    Inventors: Jen-Chang Yang, Sheng-Yang Lee, Tsuimin Tsai, Hong-Da Wu, Hsin-Tai Hu, Yan-Cheng Yang, Chen-Feng Ma
  • Publication number: 20130145958
    Abstract: It is an object of the present invention to provide a spinning solution for industrial production of pure chitosan fiber and the method for fabricating the same. The method comprises the steps of: step (a): screening a flake chitosan raw material and removing impurities; step (b): putting in a dissolving kettle the screened flake chitosan raw material with a weight which is 3%-8% of the total weight of the spinning solution, sealing the dissolving kettle, and evacuating into vacuum; step (c): adding 0.9%-6% acetic acid solution, and soaking at the room temperature for 40-60 minutes; step (d): uniformly stirring at a rate of 26-60 rpm for 7.5-19 hours under a pressure of ?5000 pa in the dissolving kettle, standing for 1-3 hours, and obtaining a spinning solution.
    Type: Application
    Filed: March 24, 2011
    Publication date: June 13, 2013
    Applicant: SHANDONG HUAXING HAICI NEW MATERIALS CO., LTD.
    Inventors: Jiacun Zhou, Guangmin Hu
  • Patent number: 8444968
    Abstract: The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: May 21, 2013
    Assignee: Isto Technologies, Inc.
    Inventors: Mitchell S. Seyedin, Matthew Matava
  • Publication number: 20120279421
    Abstract: Thermoplastic polymer compositions comprising starch and articles made therefrom are water stable or may be rendered so. One method of making water stable thermoplastic compositions comprises the steps of mixing destructured starch with polyhydric alcohol and acid, and forming an ester condensation reaction product from at least a portion of the polyhydric alcohol and acid. In some embodiments, a pre-polymer formed from the ester condensation reaction may be provided as a pre-polymer that is mixed with the starch.
    Type: Application
    Filed: July 18, 2012
    Publication date: November 8, 2012
    Inventors: Isao Noda, Michael M. Satkowski, William M. Allen, JR., James T. Knapmeyer
  • Publication number: 20120270046
    Abstract: Hydroxyl polymer-containing compositions, especially hydroxyl polymer-containing compositions that can be processed into polymeric structures, especially polymeric structures in the form of fibers are provided.
    Type: Application
    Filed: July 3, 2012
    Publication date: October 25, 2012
    Inventors: Paul Arlen Forshey, Gregory Charles Gordon, Larry Neil Mackey, Mark Ryan Richards
  • Publication number: 20120216705
    Abstract: Disclosed are methods for dissolving biopolymers and synthetic polymers using mixtures of different ionic liquids and compositions comprising the mixture. The methods involve contacting a polymer with a mixture of ionic liquids to provide a composition of polymer and the mixture; the mixture of ionic liquids is prepared by either mixing ionic liquids or by a process comprising reacting ionic liquid precursors in one-pot to form the ionic liquids.
    Type: Application
    Filed: November 4, 2010
    Publication date: August 30, 2012
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA
    Inventors: Robin D. Rogers, Daniel T. Daly, Gabriela Gurau
  • Publication number: 20120171260
    Abstract: Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.
    Type: Application
    Filed: March 12, 2012
    Publication date: July 5, 2012
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Bin Huang, Lothar W. Kleiner, John Stankus
  • Publication number: 20120156562
    Abstract: A water-based slurry composition contains (1) a water-based medium containing at least water as a polar solvent, (2) at least one polymer selected from cellulose derivatives, alginic acid derivatives, starch derivatives, chitin derivatives, chitosan derivatives, polyallylamine and polyvinylamine, (3) a hydrophobic filler, and (4) a polybasic acid or a derivative thereof. The composition has a water content of 30 mass % or higher. An electrode plate for an electricity storage device, and the electricity storage device are also disclosed.
    Type: Application
    Filed: August 24, 2010
    Publication date: June 21, 2012
    Applicant: DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD.
    Inventors: Nobuyuki Kobayashi, Takanori Sannan, Shinya Tsuchida, Yoshihiko Iijima
  • Publication number: 20120138247
    Abstract: Hydroxyl polymer-containing compositions, especially hydroxyl polymer-containing compositions that can be processed into polymeric structures, especially polymeric structures in the form of fibers are provided.
    Type: Application
    Filed: February 13, 2012
    Publication date: June 7, 2012
    Inventors: Paul Arlen Forshey, Gregory Charles Gordon, Larry Neil Mackey, Mark Ryan Richards
  • Publication number: 20120053261
    Abstract: The invention relates to a new biocompatible, biodegradable removable and repositionable adhesive composition, its preparation method and various uses thereof, including its use as surgical aid. The invention also discloses a matrix comprising such composition, such as e.g. a solid support covered, impregnated or saturated by said adhesive composition. Adhesive compositions according to the invention comprise at least one chitin and/or chitosan containing material. In a particular embodiment said adhesive composition further comprises at least one adhesive-enhancing agent whereby said agent is provided in a granular form, and preferably is a chitin and/or chitosan containing material as defined herein. The present adhesive composition and matrix comprising such composition can be used as gluing composition, in particular in wound-healing and/or surgical applications.
    Type: Application
    Filed: May 12, 2010
    Publication date: March 1, 2012
    Applicant: Kitozyme S.A.
    Inventor: Laurent Pravata
  • Patent number: 8092815
    Abstract: Provided are articles containing a solid surface material with an antimicrobial agent in a thermoset and/or thermoplastic resin matrix, wherein the antimicrobial agent comprises a chitosan-metal complex.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: January 10, 2012
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Subramaniam Sabesan
  • Patent number: 8088831
    Abstract: Disclosed is a cellulose ester film which is suppressed in volatilization of components during film formation, while having high surface flatness, high durability after saponification and good adhesion to a polarizer. Also disclosed is a method for producing such a cellulose ester film by melt forming. Further disclosed are a polarizing plate having high light resistance and high durability, and a liquid crystal display having high image quality. Specifically disclosed is a cellulose ester film characterized by containing a cellulose ester, a compound represented by the general formula (1) below, and a compound represented by the general formula (2) below.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: January 3, 2012
    Assignee: Konica Minolta Opto, Inc.
    Inventors: Takatugu Suzuki, Takayuki Suzuki
  • Publication number: 20110129536
    Abstract: The present invention provides nanocomposite systems made of metallic nanoparticles stabilized with branched cationic polysaccharides, in particular alditolic or aldonic mono- and oligo-saccharidic derivatives of chitosan, and their preparation obtainable with aqueous solutions of these polysaccharides in the presence or absence of reducing agents. The peculiar chemical and physical-chemical features of these polysaccharides allow to form metallic nanoparticles homogeneously dispersed in the polysaccharidic matrix and an effective stabilization thereof. The properties associated with the nanometric dimensions and the presence of biological signals on polymeric chains may be exploited in applications with antimicrobial activities and of molecular biosensors.
    Type: Application
    Filed: July 22, 2009
    Publication date: June 2, 2011
    Applicant: Universita Degli Studi di Trieste
    Inventors: Ivan Donati, Eleonora Marsich, Andrea Travan, Sergio Paoletti
  • Patent number: 7951237
    Abstract: The invention relates to a polymer composition comprising a biologically degradable polymer and a material from sea plants and/or shells of sea animals or at least two components selected from the group consisting of saccharides and the derivatives thereof, proteins, amino acids, vitamins and metal ions. The invention additionally relates to a molded article comprising said polymer composition. Said molded article may be used packaging material or fibrous material, in the form of fibrous material as mixing component for the production of yarns, and in the form of fibrous material for the production of nonwoven fabrics or woven fabrics.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: May 31, 2011
    Assignee: smartfiber AG
    Inventors: Stefan Zikeli, Thomas Endl, Michael Gert Martl
  • Patent number: 7888412
    Abstract: The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and/or copolymers, the formation of resins and blends, and the reconstitution of polymer and/or copolymer solutions, and the dissolution and blending of “functional additives” and/or various polymers and/or copolymers to form advanced composite materials.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: February 15, 2011
    Assignee: Board of Trustees of the University of Alabama
    Inventors: John D. Holbrey, Richard P. Swatloski, Ji Chen, Dan Daly, Robin D. Rogers