Aminopolysaccharide (e.g, Heparin, Glycosamine, Mucopolysaccharide, Chitin, Hyaluronic Acid, Etc.) Patents (Class 106/162.2)
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Patent number: 11220603Abstract: The invention relates to a silicate coating containing (A) at least one compound of the formula (I), where R1 represents H, C1-C4-alkyl, CH2CH2OH, or CH2CH(CH3)OH, (B) at least one silicate binder, (C) if appropriate, one or more polymer binders, (D) if appropriate, further additives usual for the production of silica coatings, and (E) water.Type: GrantFiled: April 18, 2017Date of Patent: January 11, 2022Assignee: Clariant International Ltd.Inventors: Rainer Kupfer, Jesús Pitarch López, Christoph Söffing, Jörg Rüger
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Patent number: 11067514Abstract: A sensor has a transparent polymer aerogel, and sensing materials dispersed into the transparent, polymer aerogel, where the sensing materials change color in response to environmental conditions. A method of forming a sensor includes providing a substrate, forming a polymer aerogel layer on the substrate, and infusing the polymer aerogel layer with sensing molecules.Type: GrantFiled: December 20, 2017Date of Patent: July 20, 2021Assignees: PALO ALTO RESEARCH CENTER INCORPORATED, XEROX CORPORATIONInventors: Gabriel Iftime, Jessica Louis Baker Rivest, George A. Gibson, Eric Cocker, Mahati Chintapalli, Quentin Van Overmeere
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Patent number: 10850003Abstract: A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.Type: GrantFiled: June 1, 2017Date of Patent: December 1, 2020Assignee: Cresilon, Inc.Inventor: Joseph A. Landolina
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Patent number: 10260151Abstract: Provided are a treatment liquid for a trivalent chromium conversion coating, achieving excellent corrosion resistance and scratch resistance without containing a cobalt compound, with high stability and adequate consideration for environmental issues; and a method for treating a metal substrate using the same. Provided is a treatment liquid for a trivalent chromium conversion coating on the surface of a metal substrate comprising: a trivalent chromium compound; titanium lactate; one or more compounds of transition metal other than cobalt; two or more organic acids or organic acid salts, and at least one ion species selected from chloride ions, nitrate ions, and sulfate ions; but no cobalt compound.Type: GrantFiled: December 3, 2015Date of Patent: April 16, 2019Assignee: Nippon Hyomen Kagaku Kabushiki KaishaInventors: Kazuyuki Shinozaki, Mitsuomi Katori, Hiroyuki Kaneta
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Patent number: 10214596Abstract: A process for producing chitin nanocrystals (ChNCs) involves contacting a chitinous material with a sufficient amount of an inorganic persulfate to produce chitin nanocrystals from the chitinous material. The process permits one-spot production of ChNCs from biomasses such as crustaceans, fungi, mushrooms, insects or mixtures thereof. Chitin nanocrystals produced by the process comprise surface carboxylic groups and are not initially deacetylated.Type: GrantFiled: November 12, 2014Date of Patent: February 26, 2019Inventors: John H. Luong, Edmond Lam, Chi Woon Leung, Sabahudin Hrapovic, Keith B. Male
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Patent number: 10010650Abstract: Disclosed is a composite hemocompatible material and a method for producing a composite hemocompatible material. The composite material includes a synthetic substrate and an animal biological tissue. The animal biological tissue is interlinked the synthetic substrate so as to bond the animal biological tissue to the synthetic substrate and form the composite hemocompatible material.Type: GrantFiled: November 7, 2006Date of Patent: July 3, 2018Assignee: CarmatInventors: Antoine Capel, Alain Carpentier, Marion Melot
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Patent number: 9272069Abstract: Described herein is the synthesis of adhesive complex coacervates. The adhesive complex coacervates are composed of a mixture of one or more polycations, one or more polyanions, and one of more multivalent cations. The polycations and polyanions in the adhesice complex coacervate are crosslinked with one another by covalent bonds upon curing. The adhesive complex coacervates have several desirable features when compared to conventional bioadhesives, which are effective in water-based applicatgions. The adhesive complex coacervates described herein exhibit good interfacial tension in water when applied to a substrate (i.e., they spread over the interface rather than being beaded up). Additionally, the ability of the complex coacervate to crosslink intermolecularly increases the cohesive strength of the adhesive complex coacervate. The adhesive complex coacervates have numerous biological applications as bioadhesives and drug delivery devices.Type: GrantFiled: November 13, 2008Date of Patent: March 1, 2016Assignee: University of Utah Research FoundationInventors: Russell Stewart, Hui Shao
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Patent number: 9076999Abstract: A laminating water-based surface treatment agent according to the present invention includes a chitosan derivative, a carboxyl compound having at least one carboxyl group in a molecule, and water. The content mass ratio of the chitosan derivative/the carboxyl compound falls within a range of 1.0/0.5 to 1.0/3.0. The laminating water-based surface treatment agent of the present invention can form an undercoating excellent in HF-resistance, electrolyte resistance, and solvent resistance, and also can sufficiently secure laminating adherence for a long term under more extreme environments required for a packaging material for a battery case or a tab lead for, e.g., a lithium ion secondary battery for automobiles.Type: GrantFiled: April 23, 2013Date of Patent: July 7, 2015Assignee: Showa Denko Packaging Co., Ltd.Inventors: Daisuke Hashimoto, Takurou Watanabe
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Publication number: 20150148909Abstract: A method for treating arthritis of a joint includes identifying a bone lesion in a bone adjacent to the joint; and implanting in the bone a reinforcing member in or adjacent to the bone lesion. A kit for conducting the method includes: (a) at least one reinforcing member having a proximal face adapted to face the joint, a distal face adapted to face away from the joint, and a wedge-shaped edge adapted to pierce bone, wherein the at least one reinforcing member is planar and sterile; and (b) a container adapted to maintain the at least one reinforcing member sterile. Another kit includes: (a) a sterile fluid; (b) a syringe for injecting the fluid into a bone; (c) a curing agent adapted to cure the fluid to polymerize and/or cross-link; and (d) a container adapted to maintain the sterility of contents of the container.Type: ApplicationFiled: August 18, 2014Publication date: May 28, 2015Inventors: Peter F. Sharkey, Charles F. Leinberry
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Patent number: 9023143Abstract: A cast ceiling tile and method for manufacture incorporates chitosan in an amount sufficient to provide improved strength.Type: GrantFiled: December 28, 2011Date of Patent: May 5, 2015Assignee: USG Interiors, LLCInventor: Enrique L. Albarran
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Patent number: 9017469Abstract: It is an object of the present invention to provide a spinning solution for industrial production of pure chitosan fiber and the method for fabricating the same. The method comprises the steps of: step (a): screening a flake chitosan raw material and removing impurities; step (b): putting in a dissolving kettle the screened flake chitosan raw material with a weight which is 3%-8% of the total weight of the spinning solution, sealing the dissolving kettle, and evacuating into vacuum; step (c): adding 0.9%-6% acetic acid solution, and soaking at the room temperature for 40-60 minutes; step (d): uniformly stirring at a rate of 26-60 rpm for 7.5-19 hours under a pressure of ?5000 pa in the dissolving kettle, standing for 1-3 hours, and obtaining a spinning solution.Type: GrantFiled: March 24, 2011Date of Patent: April 28, 2015Assignee: Shandong Huaxing Haici New Materials Co., LtdInventors: Jiacun Zhou, Guangmin Hu
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Publication number: 20150108410Abstract: Binder including (i) a chitosan derivative and (ii) deionized water or 1 vol. % aqueous solution of acetic acid as a dispersant. A method for preparing an electrode of a lithium ion battery by adding the binder to a conductive agent.Type: ApplicationFiled: December 23, 2014Publication date: April 23, 2015Inventors: Lingzhi ZHANG, Lu YUE, Haoxiang ZHONG
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Patent number: 8961675Abstract: An acoustic building material and method for manufacture incorporates chitosan in an amount sufficient to achieve acceptable physical properties with a reduction in binder and to allow the postindustrial/postconsumer content of the building material to be increased. The chitosan also enhances the dewatering of the building material.Type: GrantFiled: November 11, 2011Date of Patent: February 24, 2015Assignee: USG Interiors, LLCInventor: Enrique L. Albarran
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Publication number: 20150000561Abstract: The invention relates to a new hyaluronan derivative according to the general formula (I), the method of preparation thereof, a hydrogel based on the new derivative, method of preparation of the hydrogel and the use of the hydrogel in tissue engineering, cosmetics, medicine or regenerative medicine, especially in the form of scaffolds for the treatment of articular cartilage or bone tissue defects.Type: ApplicationFiled: February 26, 2013Publication date: January 1, 2015Inventors: Lucie Wolfova, Martin Pravda, Marcela Foglarova, Miroslava Nemcova, Krzysztof Niedoba, Vladimir Velebny
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Patent number: 8906881Abstract: Chitosan-based nail formulations are useful to treat nail inflammatory diseases like psoriasis, atopic dermatitis and lichen planus. The chitosan is normally in the form of an amino-polysaccharide derivative, preferably water soluble, such as hydroxypropyl chitosan. The formulation may be a nail lacquer, a spray, a cream, an ointment, a gel, a lotion or a foam and may have a content in chitosan, chitosan derivative or a salt thereof from 0.1 to 25 wt. % with respect to the total weight of the formulation.Type: GrantFiled: February 7, 2008Date of Patent: December 9, 2014Assignee: Polichem SAInventor: Federico Mailland
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Publication number: 20140331894Abstract: The present invention provides a method for preparing a water insoluble gel composition comprising: mixing a water soluble polysaccharide, an epoxy cross-linking agent, an alkaline compound and a solvent; and drying the thus obtained mixture at 1 to 30° C. under vacuum to remove the solvent, and a water insoluble gel composition.Type: ApplicationFiled: November 21, 2012Publication date: November 13, 2014Applicant: AMOREPACIFIC CORPORATIONInventors: Young Chang Ah, Sung Yeon Cho, In Seok Hwang, Sun Young Park, Hyun Ju Ko, Hyuk Kim, Min Jung Kwon, Won Seok Park
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Patent number: 8877170Abstract: The present disclosure relates to implantable medical devices having a non-bioabsorbable substrate and an amphiphilic coating covalently bonded to the substrate for reducing the inflammatory response to the device after implantation.Type: GrantFiled: February 19, 2010Date of Patent: November 4, 2014Assignee: Sofradim ProductionInventors: Sebastien Ladet, Philippe Gravagna
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Publication number: 20140294770Abstract: The present invention features, inter alia, biocompatible compositions that include a poloxamer and one or more additives such as hyaluronic acid, gelatin, fibronectin, or a peptide fragment of fibronectin. The compositions are useful in tissue repair or remodeling, including repair of an injured spinal disc, in drug delivery, in cell culture, and in inhibiting the formation of adhesions.Type: ApplicationFiled: July 5, 2012Publication date: October 2, 2014Applicant: The Research Foundation of State University of New YorkInventors: Raphael Davis, Divya Bhatnagar, Miriam Rafailovich
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Publication number: 20140289986Abstract: A cotton bud with a rod-like grip body and with a bud body that is arranged at least at one free end of the grip body. The rod-like grip body is a biologically degradable extrusion body, and includes natural fibres embedded into a material matrix.Type: ApplicationFiled: June 20, 2012Publication date: October 2, 2014Applicant: ROWEG HOLDING AGInventors: Beat Hani, Christian Rytka, Guy Petignat
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Publication number: 20140287061Abstract: A biocompatible polymeric composition for cross-linking in-situ in a wound is disclosed comprising 1) one or more polyanionic polymers such as alginates or hyaluronates, able to be cross-linked the surface of the wound and 2) one or more polycationic polymers such as chitosan or DEAE-Dextran, that assists in the solidification process as well as speeds up hemostasis without the need for applying pressure. The biocompatible polymeric composition may further comprise a cross-linking agent such as aqueous calcium chloride. The invention encompasses an initial polymeric composition, the solidified matrix cross-linked and integrated at the wound site, including the methods of using, applying, and cross-linking the composition.Type: ApplicationFiled: November 12, 2012Publication date: September 25, 2014Applicant: Suneris, Inc.Inventor: Joseph A. Landolina
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METHOD OF MANUFACTURING SOIL REINFORCED BY MICROBE-BASED BIO-BINDERS AND SOIL PRODUCED BY THE METHOD
Publication number: 20140238267Abstract: The present invention relates to a method of manufacturing soil reinforced by microbe-based bio-binders and soil produced by the method. The bio-binders are not harmful to humans, do not cause environmental pollution and secure sufficiently the soil strength and resistance against wind. According to the method, the soil is prepared by binding sand whose major components are silica and alumina, ureolytic microbes, urea, calcium ion, and polymer fibers, and the content of polymer fibers in sand ranges from 0.05 wt % to 5 wt %. In addition, it is preferable that the microbes provide CaCO3 at a rate at 1˜7×10?9 g CaCO3 ppt cell?1 hr?1 under optimum conditions.Type: ApplicationFiled: November 10, 2011Publication date: August 28, 2014Applicants: LOTTE ENGINEERING & CONSTRUCTION, SOUTH DAKOTA SCHOOL OF MINES AND TECHNOLOGY, ECHO PHILEInventors: Sang Chul Bang, Sookie S. Bang, Seong Rok Choi, Seok Jin Lee, Joo Ho Lee, Jong Sun Kim -
Publication number: 20140242870Abstract: The present invention relates to a composite including chitosan and/or chitin and a catechol-based compound, an organic reinforcing material composition including the composite, a product manufactured by using the organic reinforcing material composition, and a method for preparing a chitosan and/or chitin composite with improved strength, including the step of adding the catechol-based compound to chitosan and/or chitin. The chitosan and/or chitin composite including the catechol-based compound is advantageous in that it is able to maintain high strength in a wet-swollen state by improving the problem of strength reduction due to moisture, compared to the composites containing no catechol-based compound.Type: ApplicationFiled: September 27, 2012Publication date: August 28, 2014Inventors: Dong Soo Hwang, Dong Yeop Oh, Sang Sik Kim, Hyung Joon Cha
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Publication number: 20140242146Abstract: The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution; b) extruding said solution to an extrusion die; c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.Type: ApplicationFiled: May 5, 2014Publication date: August 28, 2014Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON IInventors: Alain DOMARD, Laurent DAVID, Florence DUPASQUIER
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Publication number: 20140205838Abstract: Hydroxyl polymer-containing compositions, especially hydroxyl polymer-containing compositions that can be processed into polymeric structures, especially polymeric structures in the form of fibers are provided.Type: ApplicationFiled: March 26, 2014Publication date: July 24, 2014Applicant: The Procter & Gamble CompanyInventors: Paul Arlen FORSHEY, Gregory Charles GORDON, Larry Neil MACKEY, Mark Ryan RICHARDS
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Publication number: 20140190367Abstract: This invention concerns a biopolymer consisting of a polysaccharide composed of galactose (50-90%), glucose (1-25%), mannose (1-25%) and rhamnose (0.5-20%), which may additionally contain, in trace amounts, xylose, fucose, ribose, arabinose and/or fructose. The galactose-rich polymer also contains non-saccharide components, namely, acyl groups. This invention also concerns a process for the production of the galactose-rich polymer, by microbial fermentation using glycerol or glycerol-rich substrates as carbon source, and recovery of the polymer from the culture broth. From the process for the production of the galactose-rich polymer results the co-production of intracellular biopolymers, namely, polyhydroxyalkanoates.Type: ApplicationFiled: March 5, 2014Publication date: July 10, 2014Applicant: 73100- SETENTA E TRES MIL E CEM, LDA.Inventors: Maria d'Ascencao Carvalho Fernandes De Miranda Reis, Rui Manuel Freitas Oliveira, Cristina Paula Pereira Da Cunha Rodrigues Oliveira, Maria Filomena Andrade De Freitas, Victor Manuel Delgado Alves, Joana Oliveira Pais
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Patent number: 8747539Abstract: There is provided an adhesive comprising chitosan an optionally a crosslinking agent. A method for preparing such an adhesive is also disclosed. A wood-panel made with such an adhesive is also provided. Moreover, a method for manufacturing a wood-based panel is provided. The method comprises preparing a mixture comprising wood, chitosan, optionally a crosslinking agent, and optionally an acid, forming a mat with the mixture, and pressing the mat under heat and pressure so as to obtain the wood-based panel.Type: GrantFiled: May 3, 2012Date of Patent: June 10, 2014Assignees: Uniboard Canada Inc., EXP Services Inc.Inventors: Andre Verville, Yves Charest, Martin Beaulieu, Stephane Chabot, Richard Lepine
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Publication number: 20140142190Abstract: Biodegradable single-phase cohesive hydrogels useful, e.g., for the formulation of viscosupplementation compositions or compositions for filling wrinkles, contain a homogeneous blend of x polymers, which may be identical or different, crosslinked prior to the interpenetration thereof by mixing in the form of a single-phase hydrogel, wherein such crosslinked polymers are insoluble in water and miscible with one another, and x ranges from 2 to 5; in one embodiment, the hydrogels are such that the x polymers have identical or different degrees of crosslinking, at least one of the x polymers having a degree of crosslinking x1 and at least one of the x polymers having a degree of crosslinking x2, with x1 being greater than or equal to x2.Type: ApplicationFiled: January 27, 2014Publication date: May 22, 2014Applicant: Laboratoires VivacyInventors: Estelle Marie Piron, Guy Vitally
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Patent number: 8703924Abstract: This invention relates to a cross-linkable chitosan composition comprising chitosan having a degree of deacetylation between 30 and 75%, wherein the chitosan is randomly deacetylated, and a cross-linking agent, wherein the molar ratio of the cross-linking agent to chitosan is 0.2:1 or less based on the number of functional groups in the cross-linking agent and the number of accessible amino groups in the chitosan. The invention also provides a chitosan hydrogel formed therefrom and uses thereof.Type: GrantFiled: October 30, 2008Date of Patent: April 22, 2014Assignee: Viscogel, ABInventor: Mats Andersson
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Publication number: 20140100436Abstract: An electrode sensor kit for establishing electrical contact with skin comprises at least one contact element and a preparation comprising a mixture of water and at least one lipid for enhancing electrical contact properties between said contact element and the skin, wherein said mixture forms an emulsion, in particular a water-in-oil or an oil-in-water emulsion, having a conductivity of less than 3 mS/cm. An electrode assembly for electrical impedance tomography which comprises said kit is characterized in that (a) said at least one contact element forms an electrode or sensor plate, and (b) said at least one contact element comprises a layer of said preparation.Type: ApplicationFiled: June 7, 2012Publication date: April 10, 2014Applicant: SWISSTOM AGInventors: Josef X. Brunner, Stephan Bohm
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Patent number: 8679437Abstract: The present application discloses a process for preparing silica particles, said process comprising the step of mixing (I) an aqueous phase and (II) an oily phase comprising pre-polymerized tetraalkoxy orthosilicate, one or more alcohols, and optionally one or more polyalkylene glycols, wherein said aqueous phase comprises, in an aqueous solvent, one or more C6-30-alkyl modified polysaccharides, and optionally one or more polyalkylene glycols.Type: GrantFiled: September 23, 2010Date of Patent: March 25, 2014Assignee: FEF Chemicals A/SInventor: Thomas Everdahl
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Publication number: 20140013998Abstract: Enzymatically degradable compositions containing biocompatible polymers reactive with glycosaminoglycan compositions having a first glycosaminoglycan compound having a first degree of acetylation and a second glycosaminoglycan compound having a second degree acetylation different than the first degree of acetylation.Type: ApplicationFiled: March 23, 2012Publication date: January 16, 2014Applicant: Sofradim ProductionInventor: Sébastien Ladet
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Publication number: 20130320271Abstract: This invention relates to a coating formulation for manufacturing an electrode plate, which contains a solution of a hydroxyalkylchitosan and an organic acid and/or its derivative in an aprotic polar solvent, and an active material added to the solution and kneaded with the solution, the electrode plate, a manufacturing process of the electrode plate, a battery, a capacitor, and an undercoating formulation. According to this invention, a coating formulation for manufacturing an electrode plate for a nonaqueous electrolyte secondary battery or an electrode plate for an electric double layer capacitor having excellent adhesion and improved contact resistance between an active material layer and a collector, the electrode plate, its manufacturing process, the battery and the capacitor can be provided.Type: ApplicationFiled: August 5, 2013Publication date: December 5, 2013Applicants: Dainichiseika Color & Chemicals Mfg. Co., Ltd., Kyoritsu Chemical & Co., Ltd.Inventors: Satoshi YAMAZAKI, Takaya Sato, Takanori Sannan, Nobuyuki Kobayashi, Shinya Tsuchida
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Publication number: 20130280593Abstract: A laminating water-based surface treatment agent according to the present invention includes a chitosan derivative, a carboxyl compound having at least one carboxyl group in a molecule, and water. The content mass ratio of the chitosan derivative/the carboxyl compound falls within a range of 1.0/0.5 to 1.0/3.0. The laminating water-based surface treatment agent of the present invention can form an undercoating excellent in HF-resistance, electrolyte resistance, and solvent resistance, and also can sufficiently secure laminating adherence for a long term under more extreme environments required for a packaging material for a battery case or a tab lead for, e.g., a lithium ion secondary battery for automobiles.Type: ApplicationFiled: April 23, 2013Publication date: October 24, 2013Applicant: SHOWA DENKO K.K.Inventors: Daisuke HASHIMOTO, Takurou WATANABE
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Publication number: 20130276669Abstract: An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N-acylchitosan hydrogel.Type: ApplicationFiled: March 26, 2013Publication date: October 24, 2013Inventor: Thomas Freier
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Patent number: 8496748Abstract: The invention relates to a polymer composition formed from a biologically degradable polymer and a material from sea plants and/or shells of sea animals or at least two components selected from the group consisting of saccharides and the derivatives thereof, proteins, amino acids, vitamins and metal ions. The invention additionally relates to a molded article formed from the polymer composition. The molded article may be packaging material or fibrous material, in the form of fibrous material as a mixing component for the production of yarns, and in the form of fibrous material for the production of nonwoven fabrics or woven fabrics.Type: GrantFiled: March 16, 2011Date of Patent: July 30, 2013Assignee: Smartfiber AGInventors: Stefan Zikeli, Thomas Endl, Michael Gert Martl
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Patent number: 8465582Abstract: The present invention relates to a process of using a heat responsive mixture to produce inorganic interconnected 3D open-cell bone substitutes which can be applied in the orthopedic or dental field for treatment of bone damage. The invention provides a simple and easily-controlled process of preparing porous inorganic bone substitute materials.Type: GrantFiled: March 16, 2010Date of Patent: June 18, 2013Assignee: Taipei Medical UniversityInventors: Jen-Chang Yang, Sheng-Yang Lee, Tsuimin Tsai, Hong-Da Wu, Hsin-Tai Hu, Yan-Cheng Yang, Chen-Feng Ma
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Publication number: 20130145958Abstract: It is an object of the present invention to provide a spinning solution for industrial production of pure chitosan fiber and the method for fabricating the same. The method comprises the steps of: step (a): screening a flake chitosan raw material and removing impurities; step (b): putting in a dissolving kettle the screened flake chitosan raw material with a weight which is 3%-8% of the total weight of the spinning solution, sealing the dissolving kettle, and evacuating into vacuum; step (c): adding 0.9%-6% acetic acid solution, and soaking at the room temperature for 40-60 minutes; step (d): uniformly stirring at a rate of 26-60 rpm for 7.5-19 hours under a pressure of ?5000 pa in the dissolving kettle, standing for 1-3 hours, and obtaining a spinning solution.Type: ApplicationFiled: March 24, 2011Publication date: June 13, 2013Applicant: SHANDONG HUAXING HAICI NEW MATERIALS CO., LTD.Inventors: Jiacun Zhou, Guangmin Hu
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Patent number: 8444968Abstract: The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.Type: GrantFiled: December 7, 2006Date of Patent: May 21, 2013Assignee: Isto Technologies, Inc.Inventors: Mitchell S. Seyedin, Matthew Matava
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Publication number: 20120279421Abstract: Thermoplastic polymer compositions comprising starch and articles made therefrom are water stable or may be rendered so. One method of making water stable thermoplastic compositions comprises the steps of mixing destructured starch with polyhydric alcohol and acid, and forming an ester condensation reaction product from at least a portion of the polyhydric alcohol and acid. In some embodiments, a pre-polymer formed from the ester condensation reaction may be provided as a pre-polymer that is mixed with the starch.Type: ApplicationFiled: July 18, 2012Publication date: November 8, 2012Inventors: Isao Noda, Michael M. Satkowski, William M. Allen, JR., James T. Knapmeyer
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Publication number: 20120270046Abstract: Hydroxyl polymer-containing compositions, especially hydroxyl polymer-containing compositions that can be processed into polymeric structures, especially polymeric structures in the form of fibers are provided.Type: ApplicationFiled: July 3, 2012Publication date: October 25, 2012Inventors: Paul Arlen Forshey, Gregory Charles Gordon, Larry Neil Mackey, Mark Ryan Richards
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Publication number: 20120216705Abstract: Disclosed are methods for dissolving biopolymers and synthetic polymers using mixtures of different ionic liquids and compositions comprising the mixture. The methods involve contacting a polymer with a mixture of ionic liquids to provide a composition of polymer and the mixture; the mixture of ionic liquids is prepared by either mixing ionic liquids or by a process comprising reacting ionic liquid precursors in one-pot to form the ionic liquids.Type: ApplicationFiled: November 4, 2010Publication date: August 30, 2012Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMAInventors: Robin D. Rogers, Daniel T. Daly, Gabriela Gurau
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Publication number: 20120171260Abstract: Stents and delivery systems with reduced chemical degradation and methods of sterilizing the same are disclosed.Type: ApplicationFiled: March 12, 2012Publication date: July 5, 2012Applicant: Abbott Cardiovascular Systems Inc.Inventors: Bin Huang, Lothar W. Kleiner, John Stankus
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Publication number: 20120156562Abstract: A water-based slurry composition contains (1) a water-based medium containing at least water as a polar solvent, (2) at least one polymer selected from cellulose derivatives, alginic acid derivatives, starch derivatives, chitin derivatives, chitosan derivatives, polyallylamine and polyvinylamine, (3) a hydrophobic filler, and (4) a polybasic acid or a derivative thereof. The composition has a water content of 30 mass % or higher. An electrode plate for an electricity storage device, and the electricity storage device are also disclosed.Type: ApplicationFiled: August 24, 2010Publication date: June 21, 2012Applicant: DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD.Inventors: Nobuyuki Kobayashi, Takanori Sannan, Shinya Tsuchida, Yoshihiko Iijima
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Publication number: 20120138247Abstract: Hydroxyl polymer-containing compositions, especially hydroxyl polymer-containing compositions that can be processed into polymeric structures, especially polymeric structures in the form of fibers are provided.Type: ApplicationFiled: February 13, 2012Publication date: June 7, 2012Inventors: Paul Arlen Forshey, Gregory Charles Gordon, Larry Neil Mackey, Mark Ryan Richards
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Publication number: 20120053261Abstract: The invention relates to a new biocompatible, biodegradable removable and repositionable adhesive composition, its preparation method and various uses thereof, including its use as surgical aid. The invention also discloses a matrix comprising such composition, such as e.g. a solid support covered, impregnated or saturated by said adhesive composition. Adhesive compositions according to the invention comprise at least one chitin and/or chitosan containing material. In a particular embodiment said adhesive composition further comprises at least one adhesive-enhancing agent whereby said agent is provided in a granular form, and preferably is a chitin and/or chitosan containing material as defined herein. The present adhesive composition and matrix comprising such composition can be used as gluing composition, in particular in wound-healing and/or surgical applications.Type: ApplicationFiled: May 12, 2010Publication date: March 1, 2012Applicant: Kitozyme S.A.Inventor: Laurent Pravata
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Patent number: 8092815Abstract: Provided are articles containing a solid surface material with an antimicrobial agent in a thermoset and/or thermoplastic resin matrix, wherein the antimicrobial agent comprises a chitosan-metal complex.Type: GrantFiled: April 22, 2008Date of Patent: January 10, 2012Assignee: E. I. du Pont de Nemours and CompanyInventor: Subramaniam Sabesan
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Patent number: 8088831Abstract: Disclosed is a cellulose ester film which is suppressed in volatilization of components during film formation, while having high surface flatness, high durability after saponification and good adhesion to a polarizer. Also disclosed is a method for producing such a cellulose ester film by melt forming. Further disclosed are a polarizing plate having high light resistance and high durability, and a liquid crystal display having high image quality. Specifically disclosed is a cellulose ester film characterized by containing a cellulose ester, a compound represented by the general formula (1) below, and a compound represented by the general formula (2) below.Type: GrantFiled: July 3, 2008Date of Patent: January 3, 2012Assignee: Konica Minolta Opto, Inc.Inventors: Takatugu Suzuki, Takayuki Suzuki
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Publication number: 20110129536Abstract: The present invention provides nanocomposite systems made of metallic nanoparticles stabilized with branched cationic polysaccharides, in particular alditolic or aldonic mono- and oligo-saccharidic derivatives of chitosan, and their preparation obtainable with aqueous solutions of these polysaccharides in the presence or absence of reducing agents. The peculiar chemical and physical-chemical features of these polysaccharides allow to form metallic nanoparticles homogeneously dispersed in the polysaccharidic matrix and an effective stabilization thereof. The properties associated with the nanometric dimensions and the presence of biological signals on polymeric chains may be exploited in applications with antimicrobial activities and of molecular biosensors.Type: ApplicationFiled: July 22, 2009Publication date: June 2, 2011Applicant: Universita Degli Studi di TriesteInventors: Ivan Donati, Eleonora Marsich, Andrea Travan, Sergio Paoletti
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Patent number: 7951237Abstract: The invention relates to a polymer composition comprising a biologically degradable polymer and a material from sea plants and/or shells of sea animals or at least two components selected from the group consisting of saccharides and the derivatives thereof, proteins, amino acids, vitamins and metal ions. The invention additionally relates to a molded article comprising said polymer composition. Said molded article may be used packaging material or fibrous material, in the form of fibrous material as mixing component for the production of yarns, and in the form of fibrous material for the production of nonwoven fabrics or woven fabrics.Type: GrantFiled: December 5, 2006Date of Patent: May 31, 2011Assignee: smartfiber AGInventors: Stefan Zikeli, Thomas Endl, Michael Gert Martl
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Patent number: 7888412Abstract: The present invention relates to processes utilizing ionic liquids for the dissolution of various polymers and/or copolymers, the formation of resins and blends, and the reconstitution of polymer and/or copolymer solutions, and the dissolution and blending of “functional additives” and/or various polymers and/or copolymers to form advanced composite materials.Type: GrantFiled: March 24, 2005Date of Patent: February 15, 2011Assignee: Board of Trustees of the University of AlabamaInventors: John D. Holbrey, Richard P. Swatloski, Ji Chen, Dan Daly, Robin D. Rogers