Abstract: The present invention relates to a linker of the following formula (I) or a salt thereof: (I). The present invention relates to a linker-drug conjugate of the following formula (II) or a salt thereof: (II). The present invention relates also to a binding unit-drug corrugate, such as an antibody-drug conjugate, of the following formula (III) or (IV) or a salt thereof: (III), (IV), as well as a pharmaceutical composition comprising such a binding unit-drug corrugate and its use in the treatment of cancer.

Abstract: A method of limiting the spread of the norovirus within a cruise ship comprising: identifying a surface within a common area of a cruise ship that passengers are likely to touch; and applying a silane quaternary ammonium ion or salt thereof to the surface. The common area can be an elevator and the surface an elevator button. The common area can be a stairway and the surface a handrail. The common area can be a casino. The common area can be a dining room. The common area can be a walkway and the surface a handrail. The silane quaternary ammonium ion or salt thereof can be 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium ion, 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium chloride, 3-(trihydroxysilyl)propyldimethyloctadecyl ammonium ion, or 3-(trihydroxysilyl)propyldimethyloctadecyl ammonium chloride. Applying the silane quaternary ammonium ion or salt thereof to the surface comprises applying a solution including the silane quaternary ammonium ion or salt thereof and a solvent.

Abstract: The present disclosure relates to antimicrobial, antiviral or biocide coatings, coated objects and coating methods including a first component and a second component where the first component can provide persistent antimicrobial, antiviral or biocide kill (e.g. physically ruptures the cell membrane of the microorganism to kill upon contact).

Abstract: An aqueous fabric spray composition, comprising: a. 1-10 w.t. % silicone, wherein the silicone is in the form of an emulsion, the emulsion having a particle size of 1 nm to 150 nm b. Free perfume, having an emulsion particle size of 1 nm to 30 ?m.

Abstract: Disclosed herein are aqueous coating compositions containing an anionically stabilized polymer, one or more derivatized polyamines, and a volatile base. Coating compositions can farther include one or more additional copolymers, which may or may not be anionically stabilized, and/or additional additives, including pigments, defoamers, pigment dispersing agents, thickeners, surfactants, and combinations thereof. By incorporating a derivatized polyamine, such as an alkoxylated polyamine, the setting time of the coating compositions can be decreased. Also provided are coatings formed from the coating compositions described herein, as well as methods of forming these coatings.

Abstract: The invention relates to a biocidal composition containing 5-chlorine-2-methylisothiazolin-3-one and at least one other component selected from the group consisting of 1,2-benzisothiazolin-3-one, 2-bromine-2-nitropropane-1,3-diol and zinc. The claimed biocidal composition is characterized in that it contains methyl-4-isothiazolin-3-one in the region of between 0-2 wt. %, in relation to the total proportion of 5-chlorine-2-methyl-4-isothiazolin-3-ones. The invention also relates to the use of the claimed biocidal compositions for conserving technical products.

Abstract: The present invention relates to a method for producing copper ammonia solutions by reacting a cuprous oxide with ammonia, carbon dioxide and an oxidant. The resulting copper-containing solution can then be used to formulate a variety of wood preserving products.

Abstract: A composition for artificial marble, of the present invention comprises: a binder resin; an inorganic filler excluding zinc oxide; and zinc oxide, wherein the zinc oxide has a size ratio (B/A), in which peak A is a 370 nm to 390 nm region and peak B is a 450 nm to 600 nm region, of approximately 0.01 to 1 during photoluminescence measurement, and has a BET surface area of approximately 10 m2/g or less.

Abstract: The present invention relates to a solution for resisting destruction of living plants and a related method. A solution including a buffered amine oxide admixed with at least one material selected from the group consisting of insecticides and fungicides is applied to the living plant and provides a synergistically effective greater resistance to living plant deterioration than any of the individual buffered amine oxide, insecticides and fungicides achieve. A related method is disclosed.

Abstract: A method for manufacturing an organism adhesion reduction paint includes a first process of gelling a raw material composition that includes polyvinyl alcohol and at least one of a hydroxyl group-containing inorganic compound or an inorganic oxide; a second process of drying and subsequently pulverizing a resulting product in the first process to thereby obtain a composite gel fine powder; and a third process of adding the composite gel fine powder to a main component of a two-component urethane paint and stirring, to thereby prepare a main component of the organism adhesion reduction paint, and also adding a curing agent immediately before use.

Abstract: With the binder produced according to the invention, a number of coating products can be produced which adhere to plastics directly and without any chemical or physical pretreatment. Base coats, high-gloss lacquers, metallic lacquers, clear lacquers and effect lacquers can be produced which can be applied directly on plastics; this is an absolute novelty because pretreatment is no longer required. With the binder according to the invention it is also possible to formulate adhesives which guarantee very good bonding between plastics themselves and also paperboard packaging. The invention relates to the binder as well as base coats based on them, one-coat lacquers and adhesives.

Abstract: The present invention relates to a photocatalyst composition having visible light activity for hydrogen production through water splitting. More particularly, the present invention discloses a photocatalyst composition comprising a zinc oxide nanoparticles and a conjugated organic moiety selected from the group consisting of oligothiophenes, azo dyes, and perylenes.

Abstract: An antimicrobial and algicidal agent for cooling water system contains an antimicrobial agent and an isothiazolone-based compound that effectively kill and remove the algae grown in the cooling water system.

Abstract: Disclosed herein are aqueous coating compositions containing an anionically stabilized polymer, one or more derivatized polyamines, and a volatile base. Coating compositions can further include one or more additional copolymers, which may or may not be anionically stabilized, and/or additional additives, including pigments, defoamers, pigment dispersing agents, thickeners, surfactants, and combinations thereof. By incorporating a derivatized polyamine, such as an alkoxylated polyamine, the setting time of the coating compositions can be decreased. Also provided are coatings formed from the coating compositions described herein, as well as methods of forming these coatings.

Abstract: This application relates to methods and compositions for cleaning and disinfecting unclean surfaces that are contaminated, typically with bacteria, viruses, yeast and molds. Broadly speaking contaminated surfaces includes hard and soft surfaces such as those found in household environments, in industrial environments, and hospitals, as well as surfaces of food products such as fruits, vegetables and meat. Further, the compositions can be prepared with naturally occurring components that are classified as generally considered as safe (GRAS) by the US FDA and/or comply with National Organic Production (NOP) standards of the USDA and can therefore be used in situations where such a classification is required such as organic food production.

Abstract: A high quality paint formulation comprises water, latex polymer, pigment, and a quaternary ammonium compound. The high quality paint is capable of killing gram positive bacteria, gram negative bacteria at a rate of greater than 3 logs within 2 hours of application of bacteria to a painted surface. The high quality paint is also capable of inactivating viruses.

Abstract: A high quality paint comprises water, latex polymer, pigment, and biocidal agent. The coating provided by the high quality paint may be capable of killing gram positive bacteria, gram negative bacteria at a rate of greater than 3 logs within 2 hours of application of bacteria to a painted surface. The coating provided by the high quality of paint may be capable of continuing to kill gram positive bacteria, gram negative bacteria at a rate of greater than 1 log within 2 hours even after repeated contamination of the surface. The coating provided by the high quality paint may be capable of delivering residual killing of gram positive bacteria, gram negative bacteria for up to 48 months. The coating provided by the high quality paint may also be capable of inactivating viruses.

Abstract: A high quality paint formulation comprises water, latex polymer, pigment, and a quaternary ammonium compound. The high quality paint is capable of killing gram positive bacteria, gram negative bacteria at a rate of greater than 3 logs within 2 hours of application of bacteria to a painted surface. The high quality paint is also capable of inactivating viruses.

Abstract: Supramolecular polymers or materials that exhibit high stiffness and can efficiently be healed. The supramolecular materials polymer is based on monomers having three or more same or different binding sites that permit non-covalent, directional interactions between multiple monomer molecules. The properties of the supramolecular networks formed from the monomers are governed by cross-linked architecture and the large weight-fraction of the binding motif. The material in one embodiment forms a disordered glass, which in spite of the low-molecular weight of the building block, displays typical polymeric behavior. The material exhibits high stiffness and offers excellent coating and adhesive properties. On account of reversible dissociation and the formation of a low-viscosity liquid upon application of an optical stimulus or thermal stimulus or both, rapid healing as well as (de)bonding are possible.

Abstract: A paint system contains an anti-fouling metal oxide and a fumed silica, wherein the fumed silica has a BET surface area of 150 to 400 m2/g, a tamped density of 100 to 300 g/l and a thickening of less than 500 mPas.

Abstract: The invention relates to an aqueous coating composition comprising a compound having reactive groups A, and a quaternary ammonium compound according to Formula I, II or III wherein R1 is an alkyl, alkenyl, alkylaryl or arylalkyl group having from 5 to 50 carbon atoms; R2 is a C1-C100 hydrocarbyl group, optionally containing heteroatoms; R3 and R4 are alkylene groups having from 1 to 4 carbon atoms; R5 and R6 are H or C1-C100 hydrocarbyl group, optionally containing heteroatoms; R7 is a C1-C100 hydrocarbyl group, optionally containing heteroatoms; R8 is a C1-C100 hydrocarbyl group, optionally containing heteroatoms; R9 is H or a methyl group; Z is a substituent containing at least one reactive group B which is capable of reacting with the reactive group A; X? is an anion; y is 0 or 1; a is 0 or 1; and the sum of y and a is 1 or 2 and m is an integer from 1 to 30, preferably between 1 and 10, or between 2 and 6 n is an integer from 0-30, preferably between 1 and 10, or 2 and 6 T is a monomer unit; U is a mo

Abstract: Disclosed herein are methods for preventing biofilm formation on a surface. The present disclosure also relates to anti-biofilm forming agents, to methods of producing and using them, and to anti-fouling coatings produced therefrom.

Abstract: The invention pertains to an antimicrobial disinfecting composition including: a) 0.1-1 wt. % of each of at least one food allowed organic acid or a salt thereof; b) 0.1-1 wt. % of each of at least one amine oxide amphoteric surfactant, the composition having a total surfactant content which does not exceed 8 wt. %, wherein the total amount of betaine amphoteric surfactants in the composition is in the range of 0-75 wt. % of the total amount of amine oxide amphoteric surfactant. The composition is particularly suitable for use on skin or mucous membranes. On the one hand it shows good disinfecting properties, but on the other hand it does not lead to any use precautions or hazard or warning statements on the product label.

Abstract: A granularized sulfonated humate powder material is provided that includes a sulfonated cationic humate composed of at least one of humic acid, fulvic acid, or a combination thereof in the form of granules of from 0.1 to 6 millimeters in size. The humate powder material is water soluble with limited dusting and the ability to form a concentrated solution for application. A process of formulating the sulfonated potassium humate powder in granular form includes a lignin or lignosulfonate being metered into a powder of sulfonated potassium humate to allow for granulation without a solubilizing the powder by matching a lignin particle size to a particle sizing of said powder. The lignin or lignosulfonate and the powder are mixed into the granular form with a granule size of 0.1 to 6 millimeters.

Abstract: The invention relates to an aqueous coating composition comprising a compound having reactive groups A, and a quaternary ammonium compound according to Formula I, II or III wherein R1 is an alkyl, alkenyl, alkylaryl or arylalkyl group having from 5 to 50 carbon atoms; R2 is a C1-C100 hydrocarbyl group, optionally containing heteroatoms; R3 and R4 are alkylene groups having from 1 to 4 carbon atoms; R5 and R6 are H or C1-C100 hydrocarbyl group, optionally containing heteroatoms; R7 is a C1-C100 hydrocarbyl group, optionally containing heteroatoms; R8 is a C1-C100 hydrocarbyl group, optionally containing heteroatoms; R9 is H or a methyl group; Z is a substituent containing at least one reactive group B which is capable of reacting with the reactive group A; X? is an anion; y is 0 or 1; a is 0 or 1; and the sum of y and a is 1 or 2 and m is an integer from 1 to 30, preferably between 1 and 10, or between 2 and 6 n is an integer from 0-30, preferably between 1 and 10, or 2 and 6 T is a monomer unit; U is a m

Abstract: Corrosion inhibition systems, including coated substrates, coating materials and corrosion inhibition compounds, and methods of making the same are disclosed. These systems and methods include corrosion inhibition compounds that are responsive to corrosion at a surface, releasing active inhibitor groups upon a corrosion stimulus. The active inhibitor groups are selected to block corrosion at the surface by inhibiting oxidation reactions, reduction reactions and/or by forming a passivation layer.

Abstract: The present invention provides a method of manufacturing a phosphor for a light-emitting diode, including filling a phosphor frame in which phosphor models are formed in an engraving form with a fluorescent material solution including a fluorescent material that converts light provided by the light-emitting diode into white light by changing a wavelength of the light provided by the light-emitting diode, polishing a top surface of the phosphor frame filled with the fluorescent material solution, and drying the phosphor frame filled with the fluorescent material solution and polished.

Abstract: A cuprous oxide particle dispersion liquid includes: cuprous oxide particles; 20 to 100 parts by mass of a phosphate ester-based anionic surfactant per 100 parts by mass of the cuprous oxide particles; and 500 to 10000 parts by mass of an organic solvent per 100 parts by mass of the cuprous oxide particles. The cuprous oxide particles have an average primary particle diameter of 2 nm to 80 nm and have an average secondary particle diameter of 50 nm to 150 nm, the average secondary particle diameter being measured by dynamic light scattering using cumulant analysis. A coating agent composition includes the cuprous oxide particle dispersion liquid and a binder resin, wherein the cuprous oxide particles are contained in a range from 0.1 to 50 parts by mass in 100 parts by mass of a non-volatile matter content of the coating agent composition. An antibacterial/antiviral member includes a substrate and a coating film formed on the substrate and containing the coating agent composition.

Abstract: A synergistic antimicrobial composition containing flurochloridone and 3-Iodo-2-propynyl-butylcarbamate is provided. Also provided is a method of inhibiting the growth of or controlling the growth of microorganisms in a building material by adding such a synergistic antimicrobial composition. Also provided is a coating composition containing such a synergistic antimicrobial composition, and a dry film made from such a coating composition.

Abstract: A high quality paint formulation comprises water, latex polymer, pigment, and a quaternary ammonium compound. The high quality paint is capable of killing gram positive bacteria, gram negative bacteria at a rate of greater than 3 logs within 2 hours of application of bacteria to a painted surface. The high quality paint is also capable of inactivating viruses.

Abstract: A method of protecting wood through enhanced penetration of wood preservatives includes providing a solution including (a) at least one amine oxide, (b) at least one organic wood preservative and (c) a non-borate buffering based agent. The solution has a pH of 5 to 12.4 and preferably about 7 to 10. The solution is applied to the surface of the wood after which, with or without intervening storage, the materials are activated to effect enhanced penetration of the organic wood preservative into the wood. One may effect application at a solution temperature of about 30° C. to 75° C. and preferably about 50° C. to 60° C. to effect activation at a higher temperature and high relative humidity. In a preferred practice, the wood may be heated before and/or after application of the solution. The solution is also disclosed as a product.

Abstract: A wood preservative includes injectable particles comprising one or more sparingly soluble copper salts. The copper-based particles are sufficiently insoluble so as to not be easily removed by leaching but are sufficiently soluble to exhibit toxicity to primary organisms primarily responsible for the decay of the wood. Exemplary particles contain for example copper hydroxide, basic copper carbonate, copper carbonate, basic copper sulfates including particularly tribasic copper sulfate, basic copper nitrates, copper oxychlorides, copper borates, basic copper borates, and mixtures thereof. The particles typically have a size distribution in which at least 50% of particles have a diameter smaller than 0.25 ?m, 0.2 ?m, or 0.15 ?m. At least about 20% and even more than 75% of the weight of the particles may be composed of the substantially crystalline copper salt. Wood or a wood product may be impregnated with copper based particles of the invention.

Abstract: A marking system comprises a substrate having a surface coated with a color-triggering developer and a deactivating ink composition; and a marking composition comprising at least one color precursor. At least one “non-color developing portion” of the surface is coated with both the color-triggering developer and the deactivating ink composition, and at least one “color-developing portion” of the surface is coated with the color-triggering developer and is not coated with the deactivating ink composition. Color development occurs at the color-developing portion(s) and does not occur at the non-color developing portion(s) upon application of the marking composition to the surface of the substrate.

Abstract: The invention relates to a method of neutralizing paints, that includes adding at least one associative neutralizing agent to a formulation such as a pigment concentrate, a white paint base or paint. The associative neutralizing agent includes at least one neutralizing group N and at least one nitrogenous associative group A bonded together by at least one “spacer” group Sp. The invention also relates to pigment concentrates and to paints containing at least one such associative neutralizing agent.

Abstract: The copolymer of styrene and methylmethacrylate containing reduced graphene oxide/silver nanoparticles (PS-PMMA/RGO/AgNPs) nanocomposite were prepared via in situ bulk polymerization method using two different preparation techniques. In the first approach, a mixture of graphene oxide (GO), styrene (S) and methylmethacrylate monomers (MMA) were polymerized using a bulk polymerization method with a free radical initiator. After the addition silver nitrate (AgNO3), the product was reduced via microwave irradiation (MWI) in presence of the reducing agent hydrazine hydrate (HH), to obtain R-(GO-(PS-PMMA))/AgNPs nanocomposite. This nanocomposite was then used to create a material that had antimicrobial properties to be used in medical devices or medical related implants.

Abstract: Hydrophilic coating compositions and methods to make and use the compositions are disclosed. The compositions include a photocatalytic pigment material made up of an inorganic pigment and a monomeric anti-oxidants and free radical scavenger that is contacted to the surface of the inorganic pigment.

Abstract: An aqueous liquid solution containing soluble salts of coloring metals—particularly manganese and ferric iron along with a sugar source and fulvic and/or humic acid can be readily applied to galvanized metal surfaces impart a natural color tone to such surfaces. In this manner the visibility manmade structures like fences and guardrails is quickly and easily reduced and readily blended into the natural background. The liquid solution can be readily sprayed on galvanized surfaces. When the ambient temperature is warm natural color will develop two-three weeks.

Abstract: Ink for use in a printer for forming coating or a colored ink on a substrate is disclosed. The coating or colored image provides antibacterial and antifungal protection. The inks include a mixture of solvent and a silver sulfate biocide having a concentration range of 0.0005 to 0.5 weight %.

Abstract: A composition for reducing bacterial biofilm formation after endodontic therapy comprising water, ethanol, benzalkonium chloride, citric acid, and Triton X-100. A method of making a composition for reducing bacterial biofilm A method for reducing bacterial biofilm formation after a dental procedure.

Abstract: Disclosed herein is a reinforced composition comprising: 55 to 80 wt % of a compatibilized blend of a polyphthalamide and a poly(phenylene ether) wherein said compatibilized blend is formed from a mixture of polyphthalamide and poly(phenylene ether) in a ratio of between 1.5:1 and 7.0:1, and a functionalizing agent in an amount sufficient to effect compatibilization; and 20 to 45 wt % of a nylon glass fiber, wherein the composition contains less than 0.1 wt % of phosphinates and less than 0.1 wt % of impact modifiers and weight percent is based on the total weight of the composition.

Abstract: An antimicrobial composition comprising an organic antimicrobial component (K) and at least one metal salt component (M) and also, where appropriate, a solvent (L) and further auxiliary components, which comprises as organic component (K) at least one compound of the general formula (I) where the radicals independently have for example the following meanings: R1 is a branched or unbranched alkyl radical having 1 to 12 carbon atoms, R2 is a branched or unbranched alkyl radical having 1 to 12 carbon atoms, R3 is a branched or unbranched alkyl radical having 1 to 12 carbon atoms, R4 is a branched or unbranched alkyl radical having 1 to 18 carbon atoms, R5 is a branched or unbranched alkyl radical having 1 to 18 carbon atoms, R6 is a branched or unbranched alkyl radical having 8 to 18 carbon atoms; n is an integer from 1 to 6, and which comprises as metal salt component (M) at least one salt of a di- to pentavalent metal, is useful for durable finishing of textiles.

Abstract: An ink composition is disclosed herein. The ink composition includes from about 5 wt % to about 25 wt % of a co-solvent; from about 0.025 wt % to about 0.2 wt % of i) a chelating agent represented by formula 1, wherein R? is a carboxylic acid functional group or a carboxylate salt functional group and n>2; ii) a chelating agent represented by formula 2:, wherein R is a carboxylic acid functional group or a carboxylate salt functional group, m is greater than or equal to 1, x is greater than or equal to 2, y is greater than or equal to 1, and z is greater than or equal to 2; iii) a chelating agent represented by formula 3, wherein any of r, s, t, or u is a sulfonic acid functional group or a sulfonate functional group; or iv) combinations of any of i, ii, and iii. The ink composition also includes a balance of water.

Abstract: A powder and gel concentrate for a sealing solution is provided. The concentrate is comprised of a biocide, dye and acid buffer. This concentrate can be hydrated or dissolved using standard tap (mineralized) water to produce a sealing solution. The acid buffer keeps the minerals in the tap water suspended in solution, thereby preventing the solid scale (mineral build-up) that would otherwise clog the filters of a sealing system.

Abstract: The present invention relates to an antibacterial portland cement which essentially comprises clinker (A), gypsum (B), mineral additive (C) and at least one antibacterial agent (D); which is used in every field wherein cement-aggregate-water combination is present together such as tile production, forming construction materials, and which enables the product in which it is used to have resistance against mold, fungus and bacteria.

Abstract: Clay composite sheets, mats, films or membranes without polymers. Methods of preparing clay composite sheets, mats, films or membranes without using polymers in the method. Methods of using clay composite sheets, mats, films or membranes prepared without using polymers. Antimicrobial dressing having organo-modified clay product. Transdermal delivery of drugs using organo-modified clay product and methods.

Abstract: The presently claimed invention provides a coating solution for an antibacterial coating, and a method for synthesizing the coating solution. The coating solution comprises ethanol, nitric acid, titanium tetraisopropoxide, water, and silver nitrate. Furthermore, a coating method for deposition of the antibacterial coating is also provided. The antibacterial coating of the present invention is effective in providing antibacterial function, easy to be manufactured, and durable.

Abstract: The present invention teaches a three-step method for an aqua based chemical composition for flame retardation. The composition comprises: Sodium Borate, Boric Acid, Guanylurea Phosphate, Hydrogen Peroxide, Magnesium Chloride, and Sodium Silicate. The referenced salts are dissolved in distilled water, and the resultant flame retarding solution is coated on substrate surfaces to be protected against flame retardation. The flame retarding composition solution from step-1 alone may be used on non-prepared substrate surfaces. The flame retarding composition solution fully satisfies the Federal Aviation Regulation (FAR) 25.853(a) vertical burn test, and Federal Aviation Regulation (FAR) 25.853(d) heat release test. The utility of the present invention extends to numerous commercial and non-commercial applications.

Abstract: Aqueous oil-in-water emulsion comprising from 1 to 70% by weight, based on the total weight of the emulsion, of functional alkoxysilanes and/or condensed oligomers thereof and/or organoalkoxysiloxanes, at least one emulsifier and water, wherein the emulsion has a pH of from 5 to 9 and preferably a mean droplet size of the disperse phase of ?0.5 ?m, and the width of the droplet size distribution, expressed as the span (Formula I), is from 0.6 to 1.2. The preparation of the emulsions having the desired droplet size distribution is carried out in apparatuses having at least one pressure stage at a pressure of from 2 to 15 MPa. The emulsion can be used for hydrophobicizing porous mineral building materials.

Abstract: Compositions having a plurality of nanoparticles and nano-sheets are disclosed. Methods of making and using the compositions are also disclosed.

Abstract: Hydrophilic, biocidal coating compositions and methods to make and use the compositions are disclosed. The coatings include compounds with quaternary amine polyethylene glycol groups and polyaminoalkyl biguanide groups as substituents. The compounds when incorporated in paints provide hydrophilic, self-cleaning and biocidal property to the coating.