For Experimental Purposes Patents (Class 119/417)
  • Patent number: 10542926
    Abstract: Described herein are various apparatus and systems useful in sensory discrimination. Through the use of a multi-well sample plate, the high-throughput analysis apparatus and method allow for rapid sensory discrimination of a large number of samples.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: January 28, 2020
    Assignee: OPERTECH BIO, INC.
    Inventors: R. Kyle Palmer, F. Raymond Salemme
  • Patent number: 10492462
    Abstract: An animal carrier has a top, bottom, front, back and sides forming a chamber, and a door. Fixed slots are formed in the sides with shiftable panels overlying the sides. The panels have shiftable slots with shiftable blockers between the slots. an enlarged opening in the front has horizontal edges extending from the top and bottom and vertical edges extending from the sides. A vertically disposed shiftable plate within the chamber is adapted to advance to expel the animal patient from the chamber. Wheels and associated fans function to create an airflow to minimize a force to move the system along a floor. A drainboard is positioned within the chamber on the bottom for draining urine to a collection zone. A slot above the collection zone is for removable receipt of a test slip for clinical analysis of the urine.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: December 3, 2019
    Inventor: Thomas Paul Cogley
  • Patent number: 10455806
    Abstract: A device and method of keeping litter in an animal cage away from equipment in an animal cage. Embodiments comprise two or more walls to define three zones in an animal cage: an equipment zone, a channel zone, and an outsize zone. The channel zone connects the outside zone with the equipment zone. Baffles in the channel zone permit access by animals but block some fraction of litter from passing from the outsize zone into the equipment zone. Embodiments include a weighing scale in the equipment zone. Embodiments include shapes that constrain devices or equipment to predetermined locations within a cage. Embodiments include methods of use and use in a vivarium.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: October 29, 2019
    Assignee: Vium Inc.
    Inventors: Kevin Harada, Joe Betts-Lacroix, Gordon Bryce Jensen
  • Patent number: 10448612
    Abstract: Provided are animal containment systems and components, including single-use animal containment cages and modular rack units. Also provided are methods for assembling and using components of the animal containment systems.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: October 22, 2019
    Assignee: Innovive, Inc.
    Inventors: Dee L. Conger, Thomas M. Perazzo
  • Patent number: 10416084
    Abstract: A test pad comprising multiple urine attribute patches and urine detection patches in a BAYER pattern is described. The test pad is suitable for automated urine analysis of multiple animals in a cage. Generalized detection patches may be arranged adjacent to and surrounding each individual test patch for a specific urine attribute. First, fresh urine is detected in a detection patch with a camera; a timer is started; then adjacent urine attribute patches are read. Once a test patch has been used once it is disregarded for future analysis.
    Type: Grant
    Filed: February 16, 2019
    Date of Patent: September 17, 2019
    Assignee: Vium, Inc.
    Inventors: Jonathan Betts-Lacroix, Laura R. Schaevitz, Kyle Howard Heath
  • Patent number: 10300246
    Abstract: A method and system for placing a device enabled for endovascular navigation, specifically a PICC catheter, and more broadly any device which is manipulated in over the wire or monorail fashion. Variants of the system comprise a guidewire for navigating through a patient's vasculature, having an electromagnetic (EM) based tracking components at or near the a leading end of the guidewire; an EM positioning field generator configured on a reference gantry; a computer and display configured to output position information of the guidewire leading end; and a servomotor delivery system actuator, mechanically coupled to the guidewire and configured for controlling the position of the guidewire.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: May 28, 2019
    Inventor: Jaywant Philip Parmar
  • Patent number: 9877460
    Abstract: It is an object of the present invention to provide an animal urinary function measuring device and an animal urinary function measuring method each with high accuracy in sampling a urine amount of an animal. There are provided an accommodating portion which accommodates an animal other than humans, a collecting portion which is provided below the accommodating portion and collects urine discharged by the animal in the accommodating portion, a reticulated portion which is provided below the accommodating portion, allows the passage of the urine of the animal into the collecting portion, collects an object other than the urine, and whose wire diameter of a net thereof being not more than 0.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: January 30, 2018
    Assignee: LSI MEDIENCE CORPORATION
    Inventors: Ryoji Mizumachi, Hiroaki Fukuda
  • Patent number: 9789480
    Abstract: An aseptic manipulation system comprises first and second operation chambers, an aseptic manipulation chamber, and a control unit. The control unit controls the ventilation of the first operation chamber for more than a first specified number of times, after an object is introduced into the first operation chamber, and ventilates the second operation chamber for more than a second specified number of times that is greater than the first specified number of times, after the object is transferred into the second operation chamber from the first chamber.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: October 17, 2017
    Assignee: SHIBUYA CORPORATION
    Inventors: Takuya Funazuka, Masaharu Shomura
  • Patent number: 9706752
    Abstract: Provided are animal containment systems and components, including single-use animal containment cages and modular rack units. Also provided are methods for assembling and using components of the animal containment systems.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: July 18, 2017
    Assignee: INNOVIVE, INC.
    Inventors: Dee L. Conger, Thomas M. Perazzo, Matthew D. d'Artenay, Francesca McGuffie
  • Patent number: 9561002
    Abstract: The present invention relates to a system device and method for monitoring infant oral motor kinetics (OMK), which can be used to assess the functional significance of the different sucking components, i.e., the plasticity of infant sucking skills in relation to their oral feeding performance, at a particular time, during the developmental period and/or during preventive or therapeutic intervention programs. It is a unique system and apparatus that provides a means to study the nonnutritive and/or nutritive sucking skills, i.e., the Suction and/or Expression components of sucking, of infants in the natural setting, i.e., during a normal feeding session.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: February 7, 2017
    Inventor: Chantal Lau
  • Patent number: 9521826
    Abstract: A system for housetraining pets through the use of separated sleeping and waste areas contained within a pet cage. The cage encloses a waste tray section that runs along the floor of the cage, which holds an absorbent pad, secured by improved retention clips, for collecting pet waste that can be removed and replaced when soiled. A bedding area made of up a rectilinear frame covered in bedding material is raised above the floor of the cage by engaging frame extensions with perforations in the exterior of the cage. The system and associated method serve to aid in conditioning a pet for proper housetraining while the pet is confined to a cage.
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: December 20, 2016
    Inventors: Gary Rybka, Michael Schoeff
  • Patent number: 9468192
    Abstract: An enclosure (1) for small animals, the enclosure comprising: an internal wall (17) that divides a space within the enclosure (1) into first (5) and second (7) regions, and a passageway (13) mounted in said internal wall (17) to extend between said regions (5, 7) so that an animal within the enclosure can pass between the first and second regions of the space; wherein the passageway (13) is movable relative to said internal wall (17) between a first operating mode in which an animal within the enclosure is able to pass between said regions and a second operating mode in which the animal is obstructed from passing between said regions.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: October 18, 2016
    Assignee: HEBE STUDIO LIMITED
    Inventors: Simon Nicholls, James Tuthill, Johannes Paul, William Windham
  • Patent number: 9155283
    Abstract: Provided herein are slidable “drawer” animal containment systems that allow for ready access to contained animals. In certain embodiments, the animal containment systems include disposable cages, and the systems are ventilated in some embodiments.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: October 13, 2015
    Assignee: INNOVIVE, INC.
    Inventors: Dee L. Conger, Francesca McGuffie, Thomas M. Perazzo, Matthew D. D'Artenay
  • Publication number: 20150128871
    Abstract: When a primate is t restrained by a movable partition wall, friction with vertical bars of a lattice of the partition wall causing damages on roots of limbs of the primate is alleviated to reduce or solve such damages. In a primate restraint device comprising a containing body having both side surfaces, a top surface and a bottom surface, a rear surface door capable of opening and shutting the rear surface side of the containing body, and a partition wall formed movably frontward and rearward in the containing body and capable of being fixed at a desired position in the containing body, some sites among vertical bar members of the partition wall, with which roots of limbs of the primate are brought into contact while the limbs are forced to protrude frontward and restrained, are covered with protective cylinders which are rotatable with respect to the vertical bar members.
    Type: Application
    Filed: October 1, 2012
    Publication date: May 14, 2015
    Applicant: SHIN NIPPON BIOMEDICAL LABORATORIES, LTD.
    Inventors: Ryoichi Nagata, Masatoshi Kashima, Hiroaki Magotani
  • Publication number: 20150128872
    Abstract: A rodent cage for housing a rodent comprises a cage body having an open bottom end and an open top end defined by integral sidewalls. An interior surface of each sidewall is adapted to carry a channel. The top end of at least one sidewall terminates below the channel to slidably accept a top panel within the channel. The top panel has at least one opening therein for passage of laboratory equipment. A tray having a bottom and upwardly extending integral tray sidewalls is proportioned so that the cage body rests within the tray during use. The cage body further includes a floor of parallel spaced rods such that bedding housed within the cage body passes through the spaces between the rods while the rodent remains within the cage body when the cage body is removed from the tray. The rodent cage is constructed of a non-permeable clear acrylic plastic.
    Type: Application
    Filed: November 12, 2013
    Publication date: May 14, 2015
    Inventors: Steven T. Marsh, Norman C. Wang
  • Publication number: 20150122194
    Abstract: A modular assembly set system for use in modular constructions suitable for behavioral research made of a polycarbonate, acrylic or other material walls with magnetic edges, joints and parts with a support base (floor) made of magnetically active metal sheet glued over a plastic inert polymer surface (or one of similar inert properties). The system comprises a multi piece set that allows to build different mazes or structures for use in behavioral, memory and health sciences studies. The magnetic edges of the walls along with joints and other pieces attaches to the metal base (floor) and permits to modularly build any configuration. The use of this device can be extended to virtually any kind of modular construction (toys, provisional constructions, stands and other low weight assembly). The walls and floor set can be used many times, and assemble and disassemble as required.
    Type: Application
    Filed: November 4, 2014
    Publication date: May 7, 2015
    Inventor: CLAUDIO ALFREDO DE LA ROSA
  • Patent number: 8985056
    Abstract: A detecting platform for holding a tiny insect includes a main body forming a containing space, which passes through the main body and is surrounded by side walls of the main body. A first side wall and a second side wall of the side walls are opposite to each other, and the area of the second side wall is smaller than that of the first side wall. The main body forms a first opening and a second opening passing through the first side wall and the second side wall respectively for the tiny insects entering and leaving the containing space. A bottom plate covers a first through surface of the containing space to form a bottom surface and a detecting area is configured thereon to holding the tiny insects. Accordingly, the tiny insects can stay on the detecting area so as to detect the characteristics of the tiny insects expediently.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: March 24, 2015
    Assignee: National Tsing Hua University
    Inventors: Rong-Shun Chen, Jhih-Shun Yang, Yu-Ching Lin, Hung-Yin Tsai, Chien-Hung Lin, Hong Hocheng, Li-An Chu
  • Patent number: 8977517
    Abstract: System and methods to evaluate and administer drugs. The present invention instantaneously identifies the effects that drugs, including appetite-affecting agents, have on animals. Data is collected automatically and analyzed and further organized to identify feeding patterns and the effect an appetite-affecting agent has on those feeding patterns. The present invention includes a system for data management, including a program with a data acquisition phase and a data analyzing phase to determine the feeding patterns of animals to aid in the evaluation of appetite-affecting drug efficacy.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: March 10, 2015
    Assignee: Creighton University
    Inventor: Roger D. Reidelberger
  • Patent number: 8918163
    Abstract: The invention facilitates transport of an immobilized, anesthetized small animal across multiple single-modality or multiple-modality imaging workstations at the same or different physical locations without loss of subject positional information. The animal holder is compatible with preclinical animal imaging stations such as micro-CT, micro-MR, micro-PET, micro-SPECT, and FMT. The animal holder is configured to be accommodated by (for example, fit within) individual imaging chambers of such instruments and is fabricated from materials that are compliant with all of the imaging modalities used. In certain embodiments, an integrated set of fiducial marker wells accommodates the dispensing of markers that are picked up by several modalities simultaneously in multiple planes. The fiducial markers then are aligned in standard image processing or image analysis software with simple image translation and rotation operations, without the need for more advanced scaling, distortion or other operations.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: December 23, 2014
    Assignee: VisEn Medical, Inc.
    Inventors: Wael I. Yared, Andrew K. Wilson
  • Publication number: 20140322462
    Abstract: The present invention relates to a polymer composition (C) comprising at least one polyaryletherketone (PAEK), at least one polyphenylsulfone (PPSU), at least one polysulfone (PSU) and glass fibers having an elastic modulus of at least 76 GPa as measured according to ASTM D2343. Polymer composition (C) is very well suited for the manufacture of articles useful in areas as various as plumbing and electronics.
    Type: Application
    Filed: December 18, 2012
    Publication date: October 30, 2014
    Applicant: SOLVAY SPECIALTY POLYMERS USA, LLC.
    Inventors: Keshav Gautam, Mohammad Jamal El-Hibri
  • Publication number: 20140305378
    Abstract: An animal kennel comprises front, rear, top, bottom, and opposite side walls that collectively define a cavity. At least a portion of the cavity has a horizontal cross-section that is bordered by the front, rear, and opposite side walls. The cross-section has a front portion and a rear portion. The front portion is narrower between the opposite side walls than the rear portion. A majority of each of the front, rear, top, bottom and opposite side walls is formed of a material that is translucent and radiolucent.
    Type: Application
    Filed: April 15, 2013
    Publication date: October 16, 2014
    Inventors: Teresa E. Lever, Joan Coates, Mitchell Allen, Laila Al-Khashti
  • Patent number: 8862201
    Abstract: Investigation of in vivo models of disease requires imaging studies involving single subjects in single imaging sessions, serial imaging of individuals or groups of subjects, and integration of data across diverse and heterogeneous experimental methodologies. Each type of experiment is preferably supported by various feature sets that can be rigorously applied to produce quantitative, reproducible results. Current imaging scanners are not equipped with standardized capability that supports an automated and scientifically rigorous workflow suited to hypothesis testing. An imaging system includes a research workstation at which a user can design, execute, study, and report imaging plans. Flexibility that comes along with a modular design of the system allows the user to customize workflow parameters for more robust hypothesis testing.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: October 14, 2014
    Assignee: Koninklijke Philips N.V.
    Inventors: Lyubomir Zagorchev, Andrew Buckler, Eric Jean
  • Patent number: 8851016
    Abstract: A breeding cage for experimental animals is composed of a box body and a cover body covered with the box body. A side of the cover body is disposed with an air intake valve and an air vent valve. A partition is disposed in the cover body to allow an inside of the cover body to define a drainage channel. Fresh air enters from the air intake valve and is then downwardly introduced into the box body through the drainage channel and pushes air originally within the box body to exhaust it away from the air vent valve to allow air within the box body to perform circulation.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: October 7, 2014
    Assignee: Rung Shin Plastic Industrial Co., Ltd.
    Inventor: Jung Yu Lin
  • Patent number: 8851017
    Abstract: An imaging system that allows for unhindered access to a sample to be imaged. A housing structure is configured with a drawer having a platform. The platform may be configured to hold a sample, such as an animal, and/or the platform may be configured to mate with a sample holding member, such as a removable carrying tray for holding the sample. The drawer presents the platform to an imaging device or system internal to the housing when in a closed, or imaging, state. When in an extended state, the drawer presents the platform external to the housing to allow unobstructed manipulation of a sample on the drawer platform (or on the sample holding member on the platform). When used, a sample holding member such as a removable carrying tray may be docked with the drawer platform, and various interconnects, such as gas ports and electrical connectors, on the sample holding member engage with corresponding elements on the platform when docked.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: October 7, 2014
    Assignee: LI-COR, Inc.
    Inventors: Andrew George Ragatz, Donald Thomas Lamb
  • Patent number: 8844470
    Abstract: An animal handling system (AMS), useful for positioning an immobilized animal in a predefined configuration, including: a proximal portion, held outside a medical device, comprises at least one inner shaft, and at least one outer shaft, the at least one outer shaft telescopically maneuverable along the at least one inner shaft to provide a telescopic mechanism of variable (proximal-) length, the proximal portion; and a distal portion comprising a configurable encapsulatable life support system (ELSS), the ELSS is rotatable and/or linearly reciprocatable along the main longitudinal axis of the shafts by means of the maneuverable telescopic mechanism of the proximal portion. The proximal portion further comprising indicia indicating the linear displacement and rotation of the ELSS of the distal portion, such that the ELSS is accurately and reversibly configured within the medical device to optimized animal analyses.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: September 30, 2014
    Assignee: Aspect Imaging Ltd
    Inventors: Uri Rapoport, Itzchak Rabinovitz
  • Patent number: 8807084
    Abstract: An animal handling system for use in a magnetic resonance device (MRD) device, including: a first elongated enclosure having a proximal end, a distal open end and a first geometry, and a second elongated enclosure having a proximal end, a distal open end and a second geometry. The first geometry comprises a first cross-sectional area that is larger than a second cross-sectional area of the second geometry. The first elongated enclosure is inserted into a first input port of the MRD device and the second elongated enclosure is inserted in a second input port of the MRD device diametrically opposite to first input port. When the first elongated enclosure and the second elongated enclosure are inserted into the respective input ports, the second elongated enclosure slides into the first elongated enclosure through the open distal end of the first elongated enclosure.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: August 19, 2014
    Assignee: Aspect Imaging Ltd.
    Inventors: Uri Rapoport, Itzchak Rabinovitz
  • Publication number: 20140158062
    Abstract: An animal handling system for use in an MRD device, including: a first elongated enclosure having a proximal end, a distal open end and a first geometry, and a second first elongated enclosure having a proximal end, a distal open end and a second geometry. The first second geometry comprises a first cross-sectional area which is larger than a second cross-sectional area of the second geometry. The first elongated enclosure is inserted into a first input port of the MRD device and the second elongated enclosure is inserted in a second input port of the MRD device diametrically opposite to second input port, such that on insertion of the first elongated enclosure into the first input port and insertion of the second elongated enclosure into the second input, the second elongated enclosure slides into the first elongated enclosure through the open distal end of the first elongated enclosure.
    Type: Application
    Filed: February 18, 2014
    Publication date: June 12, 2014
    Applicant: ASPECT IMAGING LTD.
    Inventors: Uri Rapoport, Itzchak Rabinovitz
  • Publication number: 20140109838
    Abstract: A method for facilitating the delivery of water to a plurality of cage level barrier-type cages, for housing animals for an animal study, the method including; providing a plurality of cage level barrier-type cages for an animal study at a laboratory facility site, and disposing a bag forming apparatus at a clean side of a laboratory washroom at the laboratory facility site, wherein the bag forming apparatus is capable of providing sealed bags of water for use in the cage level barrier-type cages. The method can further include providing bag material to the laboratory facility site.
    Type: Application
    Filed: October 19, 2012
    Publication date: April 24, 2014
    Applicant: HYDROPAC/LAB PRODUCTS, INC.
    Inventors: George S. Gabriel, Neil E. Campbell, Chinsoo Park
  • Patent number: 8689739
    Abstract: The present disclosure provides a system and method for displaying animals in temperature controlled enclosures.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: April 8, 2014
    Assignee: United Pet Group, Inc.
    Inventors: Stanley J. Owens, Chad W. Robbins, Joseph M. Flora, Douglas R. Carr, John Von Buelow
  • Patent number: 8683957
    Abstract: A movement analysis device for rodents capable of variably adjusting a space where a rodent is placed in order to stimulate the behavior of the rodent so that motor functions of the rodent can be analyzed more effectively. The movement analysis device for rodents includes a body including a pair of side plates distanced from each other with a predetermined gap and a connector plate connecting one ends of the side plates together, the connector plate having a slit extending from one to the other one of the side plates; and an adjustment unit including an adjustment plate configured insertable between the side plates of the body and into the slit of the connector plate of the body and a support plate extending to a height reaching from a bottom to the slit to support the adjustment plate at one portion thereof. The support plate is semi-cylindrically shaped to form a cylindrical space together with the connector plate.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: April 1, 2014
    Assignee: Seoul National University Industry Foundation
    Inventors: Kyu-Chang Wang, Sun-Ha Paek, Byung-Woo Yoon, Se-Pil Park, Do-Hun Lee
  • Patent number: 8660633
    Abstract: In a small animal imaging system (10) at least one modality (12) and a docking station (36) are provided. The docking station (36) provides a workspace (47) and docking ports (48) for preparation and holding of anesthetized animals that are awaiting imaging. For the duplication of positions, a subject mold (26) is provided that holds the subject in a reproducible position on a subject bed (16). Vital signs monitoring is also provided for subjects awaiting scans. The bed (16) includes fiducials (28) to aid in registration of like modality images and different modality images. A capsule (14) can encapsulate a single bed (16), or for tandem imaging, the capsule can encapsulate multiple-bed configurations, such as two, three, or four beds (16). For better positioning and ease of user access, a positioner (34) positions the capsule (14) from the rear of the modality (12).
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: February 25, 2014
    Assignee: Koninklijke Philips N.V.
    Inventors: Lyubomir Zagorchev, Andrew Buckler, Eric Jean, Antonio T. Latto
  • Patent number: 8590487
    Abstract: An enclosure or burrow restrains an awake animal during an imaging procedure. A tubular body, made from a radiolucent material that does not attenuate x-rays or gamma rays, accepts an awake animal. A proximal end of the body includes an attachment surface that corresponds to an attachment surface of an optically transparent and optically uniform window. An anti-reflective coating may be applied to an inner surface, an outer surface, or both surfaces of the window. Since the window is a separate element of the enclosure and it is not integrally formed as part of the body, it can be made with optically uniform thickness properties for improved motion tracking of markers on the animal with a camera during the imaging procedure. The motion tracking information is then used to compensate for animal movement in the image.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: November 26, 2013
    Assignee: UT-Battelle, LLC
    Inventor: James S. Goddard, Jr.
  • Publication number: 20130284109
    Abstract: Methods, apparatuses and systems for convenient management of animals within a rodent containment cage system that includes labeling components, receiving data, associating the data, reporting the data and/or associations and locating components within the cage system. The management of the system may be self-contained, networked through a controller, local server and/or main server.
    Type: Application
    Filed: June 28, 2013
    Publication date: October 31, 2013
    Inventors: Dee L. Conger, Cory J. Spivey, Michael A. Roes, Francesca McGuffie, Leroy Jenson
  • Patent number: 8561574
    Abstract: Embodiments of the invention include methods and apparatuses relating to animal specimen collection and animal specimen collection stations. In an embodiment, multiple chambers each contain a single animal, and wells on a removable floor on each of the chambers may collect animal specimens. The wells may be dimensioned with a depth and width such that the animals may not disturb, contact, or contaminate specimens contained within a well.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: October 22, 2013
    Assignee: Vanderbilt University
    Inventors: Elena E. Tchekneva, Mikhail M. Dikov, Veronika Kadkina, Dina Polosukhina
  • Publication number: 20130228134
    Abstract: Methods, apparatuses and systems for convenient management of animals within a rodent containment cage system that includes labeling components, receiving data, associating the data, reporting the data and/or associations and locating components within the cage system. The management of the system may be self-contained, networked through a controller, local server and/or main server.
    Type: Application
    Filed: February 25, 2013
    Publication date: September 5, 2013
    Applicant: Innovive, Inc.
    Inventors: Dee L. Conger, Cory Spivey, Michael A. Roes, Francesca McGuffie, Leroy Jenson
  • Patent number: 8522721
    Abstract: A method and apparatus that detects a condition of a cage for housing laboratory animals includes providing an animal cage including a base part and a top and cage means for automatically detecting at least one of at least one bedding condition corresponding to a humidity level or an occurring flooding condition. At least one of the resistance or the impedance of material between said pair of electrodes is determined using one of direct current (DC) or alternating current (AC). At least one of the bedding condition or the flooding condition is measured based on a rate of one or more changes of one of a resistance or an impedance of said material between said electrodes.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: September 3, 2013
    Assignee: Tecniplast S.p.A.
    Inventors: Pietro Bernardini, Giovanni Malnati
  • Publication number: 20130206077
    Abstract: An apparatus for testing and researching aquatic species is provided. The apparatus includes a housing rack for housing a tank. The apparatus further includes one or more dividers for dividing the at least one tank into one or more compartments. The apparatus further includes a collection channel and a downspout in each compartment for draining of water from each compartment. The apparatus further includes one or more lids for covering the one or more compartments.
    Type: Application
    Filed: February 13, 2013
    Publication date: August 15, 2013
    Applicant: R&D Aquatics, LLC
    Inventor: R&D Aquatics, LLC
  • Patent number: 8485133
    Abstract: A mobile platform arrangement includes a first (mobile) platform and a second (support) platform. Both are flat-bottomed members, wherein the support platform is preferably, but not exclusively, provided with sidewalls and wherein a diameter of the support platform exceeds an outer diameter of the mobile platform at least twice. The mobile platform is advantageously positioned onto and/or within the support platform. The top surface of the support platform is provided with a friction reducing surface structure. The mobile platform is therefore adjusted to perform gliding motion along and/or over the friction reducing surface, wherein acceleration necessary for performing gliding motion is imposed to the mobile platform by an external force, provided by movement of an experimental animal within the mobile platform. The mobile platform arrangement in addition may include a mechanism for securing a conscious wake and able to move experimental animal, including a head adapter and corresponding mount.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: July 16, 2013
    Assignee: Neurotar Oy
    Inventors: Sergey Osmekhin, Leonard Khirug
  • Publication number: 20130118411
    Abstract: Disclosed herein are devices, systems, and methods for measuring an electropharyngeogram (EPG) in living organisms. In some embodiments, the devices and systems disclosed herein include an array for sorting and immobilizing an organism (such as a nematode) for measurement of an EPG and/or optical imaging. Also disclosed are methods for identifying therapeutic or toxic compounds utilizing the disclosed devices and systems. In some embodiments, the methods include screening for compounds with anthelmintic activity, toxicity (for example HERG channel blockers), or candidate drugs for treatment of a variety of human and/or animal diseases.
    Type: Application
    Filed: November 9, 2012
    Publication date: May 16, 2013
    Applicants: University of Oregon
    Inventor: The State of Oregon Acting by and through the State Board of Higher E
  • Publication number: 20120312245
    Abstract: A breeding cage for experimental animals is composed of a box body and a cover body covered with the box body. A side of the cover body is disposed with an air intake valve and an air vent valve. A partition is disposed in the cover body to allow an inside of the cover body to define a drainage channel. Fresh air enters from the air intake valve and is then downwardly introduced into the box body through the drainage channel and pushes air originally within the box body to exhaust it away from the air vent valve to allow air within the box body to perform circulation.
    Type: Application
    Filed: June 8, 2011
    Publication date: December 13, 2012
    Applicant: RUNG SHIN PLASTIC INDUSTRIAL CO., LTD.
    Inventor: Jung Yu Lin
  • Patent number: 8327807
    Abstract: A laboratory specimen sealed within a chamber on an animal holder may be injected or otherwise administered material such as drugs and radioactive imagining materials from the ambient, or outside the chamber, through a sealed catheter assembly. The animal holder can be mounted on imaging machines such as MRI, X-ray, PET, CT and like imaging machines. Biologically contaminated animals are isolated within the chamber from the ambient, yet may be injected from outside the chamber thereby protecting lab technicians from contamination and isolating the animal from additional contamination from an ambient environment, such as an imaging laboratory.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: December 11, 2012
    Inventor: Chris D. Chiodo
  • Patent number: 8327804
    Abstract: A measurement object holder that holds a measurement object in an optical measurement instrument, wherein the optical measurement instrument takes, as the measurement object, a living body in which isotropic scattering of light occurs inside and receives light emitted from the measurement object is disclosed. The measurement object holder includes a block that is formed in a predetermined outer shape by a material having optical properties in which the isotropic scattering of light occurs inside; and a cavity portion that is formed inside the block, that has an inner shape following the outer shape of the measurement object and in which the measurement object is accommodated.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: December 11, 2012
    Assignee: FUJIFILM Corporation
    Inventors: Yukio Yamada, Hitoshi Shimizu, Takeshi Kimura
  • Patent number: 8291865
    Abstract: A method for facilitating the delivery of water to a plurality of cage level barrier-type cages, for housing animals for an animal study, the method including providing a plurality of cage level barrier-type cages for an animal study at a laboratory facility site, and disposing a bag forming apparatus at a clean side of a laboratory washroom at the laboratory facility site, wherein the bag forming apparatus is capable of providing sealed bags of water for use in the cage level barrier-type cages. The method can further include providing bag material to the laboratory facility site.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: October 23, 2012
    Assignee: Hydropac/Lab Products, Inc.
    Inventors: George S. Gabriel, Neil E. Campbell, Chinsoo Park
  • Publication number: 20120234255
    Abstract: A method and apparatus that detects a condition of a cage for housing laboratory animals includes providing an animal cage including a base part and a top and cage means for automatically detecting at leats one of at least one bedding condition corresponding to a humidity level or an occurring flooding condition. At least one of the resistance or the impedance of material between said pair of electrodes is determined using one of direct current (DC) or alternating current (AC). At least one of the bedding condition or the flooding condition is measured based on a rate of oen or more changes of one of a resistance or an impedance of said material between said electrodes.
    Type: Application
    Filed: March 16, 2012
    Publication date: September 20, 2012
    Applicant: TECNIPLAST S.P.A.
    Inventors: Pietro BERNARDINI, Giovanni MALNATI
  • Publication number: 20120180731
    Abstract: In one aspect, the present invention provides a housing system for conducting high throughput animal experiments. The housing system includes a home cage, at least one rotatable turnstile enclosed by housing to form two or more isolation chambers, a means for animal identification, and one or more action stations functionally coupled to one or more isolation chambers. The turnstile includes a plurality of one or more separation members rotatable about a vertical axis, each isolation chamber bounded by one or more separation members. The action stations contain one or more devices facilitating completion of at least one animal-directed or experimentor-initiated action. In a preferred embodiment, the home cage is sufficiently sized to house a plurality of small animals, such as mice. Tunnel passageways may be connected to the home cage, including one or more tunnel passageways containing a rotatable turnstile.
    Type: Application
    Filed: June 8, 2010
    Publication date: July 19, 2012
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Joseph P. Garner, Michelle Murphy Niedziela, Edward A. Fox
  • Patent number: 8220415
    Abstract: An imaging system that allows for unhindered access to a sample to be imaged. A housing structure is configured with a drawer having a platform. The platform may be configured to hold a sample, such as an animal, and/or the platform may be configured to mate with a sample holding member, such as a removable carrying tray for holding the sample. The drawer presents the platform to an imaging device or system internal to the housing when in a closed, or imaging, state. When in an extended state, the drawer presents the platform external to the housing to allow unobstructed manipulation of a sample on the drawer platform (or on the sample holding member on the platform). When used, a sample holding member such as a removable carrying tray may be docked with the drawer platform, and various interconnects, such as gas ports and electrical connectors, on the sample holding member engage with corresponding elements on the platform when docked.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: July 17, 2012
    Assignee: LI-COR, Inc.
    Inventors: Andrew George Ragatz, Donald Thomas Lamb
  • Patent number: 8205612
    Abstract: Dry powder aerosol generators and related methods are provided. The dry powder aerosol generator includes a dispersion chamber having an internal cavity therein capable of receiving a dry powdered drug. The dispersion chamber includes a dosing port defined therein that is in fluid communication with the internal cavity. A dosing chamber for receiving a test subject is attachable to the dosing port, such that, when an airflow is created within the internal cavity, any dry powdered drug contained therein may fluidize and travel into the dosing chamber to provide opportunity for inhalation of the dry powdered drug by a test subject contained within the dosing chamber.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: June 26, 2012
    Assignee: The University of North Carolina at Chapel Hill, NC
    Inventors: Anthony J. Hickey, Hugh D. C. Smyth, Martin J. Telko
  • Patent number: 8181603
    Abstract: An apparatus and method for changing laboratory animal cages wherein the apparatus includes at least one seat, of which receives a cage having a lid. The seat is provided with a mechanical system configured to pick and lift the lid.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: May 22, 2012
    Assignee: Tecniplast S.p.A.
    Inventors: Giovanni Tartaglia, Giovanni Frangelli
  • Patent number: 8171887
    Abstract: Provided are animal containment systems and components, including single-use animal containment cages and modular rack units. Also provided are methods for assembling and using components of the animal containment systems.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: May 8, 2012
    Assignee: Innovive Inc.
    Inventors: Dee L. Conger, Thomas M. Perazzo, Matthew D. d'Artenay
  • Patent number: 8161910
    Abstract: The present invention relates to an integrated RFID card holder, cage, lid or rack and system for collecting census, inventorying, and tracking of animal cages, lids, card holders, racks, and other related equipment. Preferably, the card holder is comprised of an RF transparent material such as plastic. During operation, a RFID reader reads each integrated RFID card holder attached to an animal cage for virtually linking the cage to an animal rack in effect assigning a parking spot to each animal cage within an animal cage rack system. The integrated RFID card holder can be determined to be in a room when the Received Signal Strength Indicator (RSSI) is the highest comparing multiple reads from one or many antennas.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: April 24, 2012
    Assignee: Allentown Caging & Equipment Co., Inc.
    Inventors: Michael A. Coiro, Sr., Steven J. Miller, Tom Schupsky