For Ion Exclusion Patents (Class 127/46.3)
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Patent number: 9732108Abstract: The present invention relates to a novel family of alkylated halogenated di- and trisaccharides which exhibit pharmaceutical efficacy in the areas of permeation enhancers, anti-microbial effects, anti-fugal effects, facilitation of diagnostic procedures. The invention further includes methods of treatment and diagnostic kits.Type: GrantFiled: November 4, 2013Date of Patent: August 15, 2017Inventor: Bahram Memarzadeh
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Patent number: 9233342Abstract: The invention provides an organic-inorganic porous membrane which includes metal organic silica nano-particles impregnated in a polymer. The polymer includes a property of generating porous membrane using a phase inversion technique. The invention also provides a method for preparing the organic-inorganic porous membrane.Type: GrantFiled: November 13, 2013Date of Patent: January 12, 2016Assignee: King Abdulaziz City for Science and Technology (KACST)Inventors: Nezar Hassan Mohamed Khdary, Mamdouh Abdelsalam
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Patent number: 9180089Abstract: A composition capable of attenuating platelet hyperactivation and associated methods for administering the same to a subject, the composition comprising an aqueous solution containing from about 0.1% to about 7.0% by weight of a glycosaminoglycan and from about 1.0% to about 32% by weight of a neutral polysaccharide.Type: GrantFiled: September 21, 2010Date of Patent: November 10, 2015Assignee: GLenpharma ABInventors: Peter Byron Buckley, Konrad Messmer, Mark William Phillips
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Patent number: 8414706Abstract: The process according to the invention, for producing sugar products from fruits, comprising the steps of: i) demineralizing and decolorizing a fruit juice so as to bring its solid content to comprise from 99% wt to 99.99% wt of a mixture of saccharides, alcohols and flavonoids; iii) separating by chromatography the demineralized and decolorized fruit juice so as to obtain a glucose-enriched fraction or a fructose-enriched fraction from the fruit juice. The solid content of the glucose-enriched fraction comprises at least from 70% wt to 99.99% wt of glucose; the solid content of the fructose-enriched fraction comprises from 70% wt to 99.99% wt of fructose. The low content of anions and cations of the fruit juice to be is treated by chromatography greatly increase the yield of the chromatographic treatment and the purity of the glucose- and fructose-enriched fractions obtained through it.Type: GrantFiled: September 7, 2010Date of Patent: April 9, 2013Assignee: Cantine Foraci S.R.L.Inventors: Fabio Foraci, Pietro Foraci, Alessandro Foraci
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Patent number: 8283139Abstract: Disclosed is a method of producing xylitol using a hydrolysate containing xylose and arabinose prepared from byproducts of tropical fruit biomass and more precisely, a method of producing xylitol which includes the steps of producing xylose and arabinose by the pretreatment of tropical fruit biomass byproducts including coconut shell, palm shell and oil palm empty fruit bunch (OPEFB) via acid (0.2-5%) hydrolysis and an electrodialysis and an ionic purification; and producing xylitol with high yield based on repeated batch fermentation using a hydrolysate containing xylose and arabinose as a carbon source. In addition, the present invention relates to an active carbon produced by carbonization and activation of a hydrolysate remainder of a tropical fruit shell, the byproduct of xylose and arabinose production, at a certain temperature and a preparation method of the same.Type: GrantFiled: January 25, 2008Date of Patent: October 9, 2012Assignee: CJ Cheiljedang CorporationInventors: Seung-won Park, Joo-hang Lee, Taek-beom Kim, Jung-hoon Kim, Seong-bo Kim, Sang-hoon Song, Kang-pyo Lee, Seung-bae Ji, Dong-hoon Lee, Kang-deug Lee
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Patent number: 8192629Abstract: The present invention relates to a chromatographic separation process for fractionating betaine-containing solutions by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The process provides improved separation capacity and separation efficiency without affecting the yield or purity of betaine or other products. The process can especially be applied to sequential SMB separation systems.Type: GrantFiled: February 24, 2010Date of Patent: June 5, 2012Assignee: Danisco A/SInventors: Jyrki Airaksinen, Heikki Heikkilä, Jari Lewandowski, Kari Laiho
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Patent number: 7959811Abstract: The present invention relates to a chromatographic separation process for fractionating solutions containing sugars, sugar alcohols, sugar acids and/or betaine by utilizing fractions comprising parts of the separation profile as a substituent of the eluent in a novel and inventive manner. The starting solutions are typically multicomponent plant-based extracts and hydrolysates, stillages, and fermentation products and derivatives thereof. The process prow vides improved separation capacity and separation efficiency without affecting the yield or purity of product components, such as sugars, sugar alcohols, sugar acids, and betaine. The process can especially be applied to sequential SMB separation systems.Type: GrantFiled: February 24, 2010Date of Patent: June 14, 2011Assignee: Danisco A/SInventors: Jyrki Airaksinen, Heikki Heikkilä, Jari Lewandowski, Kari Laiho, Päivi Sarmala
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Patent number: 7718070Abstract: A process for obtaining one or more than one salt of an organic acid(s), or organic acid(s), from an aqueous sugar stream comprising one or more than one mineral acid and the organic acid(s) is provided. The process comprises introducing the aqueous sugar stream to a separation system comprising one or more beds of anion exchange resin and obtaining a stream therefrom comprising the sugar. The one or more beds of anion exchange resin are then regenerated in one or more stages to produce at least one product stream comprising the organic acid, a salt of the organic acid, or a combination thereof, and a separate outlet stream comprising the mineral acid, a salt of the mineral acid, or a combination thereof. The product stream is then recovered. The separation may be conducted with two separation units, or using a single anion exchange unit.Type: GrantFiled: July 6, 2007Date of Patent: May 18, 2010Assignee: Iogen Energy CorporationInventor: Daphne Mahnon
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Patent number: 7674381Abstract: Method for preparing highly pure L-iditol, consisting in subjecting a mixture of L-iditol and of L-sorbose to a chromatographic treatment, in such a way as to obtain at least two fractions, one of which is highly enriched in L-iditol and the other of which is highly enriched in L-sorbose.Type: GrantFiled: October 17, 2005Date of Patent: March 9, 2010Assignee: Roquette FreresInventor: Patrick Fuertes
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Patent number: 7361273Abstract: The present invention relates to a method of separating sugars and sugar alcohols from each other. More particularly the present invention relates to the use of a weakly basic anion exchange resin in a chromatographic separation process. The advantage of the present invention compared with the prior art is that it is especially suitable for separating reducing sugars in acidic conditions as well as for example in weakly acidic conditions. The method using chromatographic separation comprises at least one step where a weakly basic anion exchange resin is used in a chromatographic column or in a part of a column.Type: GrantFiled: March 26, 2003Date of Patent: April 22, 2008Assignee: SaniscoSweetners OyInventors: Heikki Heikkilä, Päivi Sarmala, Ari Kärki, Nina Nurmi, Hannu Paananen
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Publication number: 20080041366Abstract: A process for obtaining one or more than one salt of an organic acid(s), or organic acid(s), from an aqueous sugar stream comprising one or more than one mineral acid and the organic acid(s) is provided. The process comprises introducing the aqueous sugar stream to a separation system comprising one or more beds of anion exchange resin and obtaining a stream therefrom comprising the sugar. The one or more beds of anion exchange resin are then regenerated in one or more stages to produce at least one product stream comprising the organic acid, a salt of the organic acid, or a combination thereof, and a separate outlet stream comprising the mineral acid, a salt of the mineral acid, or a combination thereof. The product stream is then recovered. The separation may be conducted with two separation units, or using a single anion exchange unit.Type: ApplicationFiled: July 6, 2007Publication date: February 21, 2008Applicant: IOGEN ENERGY CORPORATIONInventor: Daphne Wahnon
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Patent number: 7314528Abstract: The invention relates to removing crystallization inhibitors from a solution comprising one or more reducing sugars by nanofiltration, hydrolysis and/or chromatography. The reducing sugars are typically selected from fructose and xylose.Type: GrantFiled: January 22, 2007Date of Patent: January 1, 2008Assignee: Danisco Sweeteners OyInventors: Hannu Koivikko, Minna Kaarto, Heikki Heikkilä, Mirja Lindroos, Juha Nurmi
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Patent number: 7229558Abstract: A method for fractionating a solution into two or more fractions. More particularly the invention relates to a method for fractionating a solution by a chromatographic simulated moving bed (SMB) process in which the dissolved substances present in the feedstock are separated in the partial packed beds, and the formed separation profile is circulated more than once or less than once through the chromatographic separation loop during one cycle.Type: GrantFiled: January 11, 2005Date of Patent: June 12, 2007Assignee: Danisco Sweeteners OyInventors: Heikki Heikkilä, Jari Lewandowski, Jarmo Kuisma
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Patent number: 7022239Abstract: The present invention relates to a method of fractionating liquid mixtures or solutions, comprising the steps of subjecting a feed in the form of a liquid mixture or solution to a first chromatographic separation, thereby recovering at least a fraction (A) and a fraction (B) both containing a first component or product, subjecting a mixture or solution derived from or comprising said fraction (A) to a second chromatographic separation, thereby recovering at least a fraction (C) rich in said first component or product and subjecting a mixture or solution derived from or comprising said fraction (B) to a third chromatographic separation, thereby recovering at least a fraction (D) also rich in said first component or product, and whereby at least two fractions are recovered from the second and third chromatographic separations.Type: GrantFiled: March 14, 2003Date of Patent: April 4, 2006Assignee: Danisco Sweeteners OyInventors: Heikki Heikkilä, Jarmo Kuisma, Jari Lewandowski, Hannu Paananen, Vili Ravanko, Jukka Rinne
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Patent number: 6987183Abstract: The present invention is directed to a method comprising a multistep process for recovering one or more monosaccharides from a solution containing at least two monosaccharides selected from the group consisting of rhamnose, arabinose, xylose and mixtures thereof by using chromatographic separation comprising at least one step, where a weak acid cation exchange resin is used for the chromatographic separation.Type: GrantFiled: September 28, 2001Date of Patent: January 17, 2006Assignee: Danisco Sweeteners OyInventors: Heikki Heikkila, Juho Jumppanen, Ve{grave over (s)}a Kurula, Vili Ravanko, Tiina Tervala, Nina Mayra
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Patent number: 6896811Abstract: A method for fractionating a solution into two or more fractions. More particularly the invention relates to a method for fractionating a solution by a chromatographic simulated moving bed (SMB) process in which the dissolved substances present in the feedstock are separated in the partial packed beds, and the formed separation profile is circulated more than once or less than once through the chromatographic separation loop during one cycle.Type: GrantFiled: May 9, 2002Date of Patent: May 24, 2005Assignee: Danisco Sweeteners OyInventors: Heikki Heikkilä, Jari Lewandowski, Jarmo Kuisma
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Patent number: 6663780Abstract: The invention relates to a method for the fractionation of molasses using a chromatographic simulated moving bed system with two or more loops in which the liquid flow can be effected in a system comprising at least two chromatographic partial packing material beds. In the method of the invention, product(s) are recovered during a process comprising one or more of the following phases: a feeding phase of molasses, an eluting phase and a recycling phase. The liquid present in the partial packing material beds with their dry solids profile can be recycled in the recycling phase in one or more loops comprising one or more partial packing material beds.Type: GrantFiled: January 31, 2002Date of Patent: December 16, 2003Assignee: Danisco Finland OyInventors: Heikki Heikkila, Jari Lewandowski, Hannu Paananen, Jarmo Kuisma, Goran Hyoky, Kaj-Erik Monten
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Patent number: 6649066Abstract: The invention relates to a method for the fractionation of molasses using a chromatographic simulated moving bed system in which the liquid flow is effected in a single direction in a system comprising at least two chromatographic partial packing material beds. In the method of the invention, the product or products are recovered during a multi-step sequence comprising the following phases: feeding phase of molasses, eluting phase and recycling phase. The liquid present in the partial packing material beds with their dry solids profile is recycled in the recycling phase in a loop comprising one, two or several partial packing material, beds.Type: GrantFiled: December 13, 2000Date of Patent: November 18, 2003Assignee: Danisco Finland OyInventors: Heikki Heikkila, Göran Hyöky, Jarmo Kuisma
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Patent number: 6451123Abstract: Improved separations of xylose, mannose, galactose, arabinose, glucose, xylitol, arabitol; sorbitol, galactitol, or mannitol (and other monosaccharides and sugar alcohols) from other sugars and sugar alcohols may be achieved by chromatography over hydroxyl-form anion exchange surfaces prepared from anion exchange resins at relatively low hydroxyl concentrations. When a strong base anion exchange resin, such as a chloride-form strong base anion exchange resin, is conditioned with a low concentration of hydroxyl (for example, an NaOH solution with a concentration between 0.1 and 1000 mM, most preferably between 1 and 10 mM), the conditioned resin separates a number of sugars and sugar alcohols from one another, while still allowing ready desorption from the resin.Type: GrantFiled: January 11, 2000Date of Patent: September 17, 2002Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Michael Saska, Feng Chen
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Patent number: 6419828Abstract: A method for separating acid and sugars obtained from liquids resulting from the acid hydrolysis of a material containing at least one of cellulose and hemicellulose is disclosed, comprising adding the liquids to a separation unit comprising a bed of anionic exchange or exclusion chromatographic material whereby the acid is adsorbed onto the chromatographic material, thereby producing a series of first fractions comprising sugar solutions and a later series of fractions comprising acid solutions. A process for an economical, energy efficient production of ethanol from municipal solid waste and other cellulosic feedstocks is also disclosed.Type: GrantFiled: October 23, 2000Date of Patent: July 16, 2002Assignee: Controlled Environmental Systems CorporationInventor: Lawrence J. Russo, Jr.
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Patent number: 6391204Abstract: A method for separating acid and sugars obtained from liquids resulting from the acid hydrolysis of a material containing at least one of cellulose and hemicellulose is disclosed, comprising adding the liquids to a separation unit comprising a bed of anionic exchange or exclusion chromatographic material whereby the acid is adsorbed onto the chromatographic material, thereby producing a series of first fractions comprising sugar solutions and a later series of fractions comprising acid solutions. A process for an economical, energy efficient production of ethanol from municipal solid waste and other cellulosic feedstocks is also disclosed.Type: GrantFiled: July 16, 1999Date of Patent: May 21, 2002Assignee: Controlled Environmental Systems CorporationInventor: Lawrence J. Russo, Jr.
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Patent number: 6383540Abstract: A method of treating whey for demineralization purposes, the method comprising a stage of separating out salts by transfer through electrodialysis or nanofiltration membranes, wherein, upstream from this separation stage, the method comprises in succession at least one step of exchanging divalent cations for protons and at least one step of exchanging divalent anions for chloride ions.Type: GrantFiled: May 3, 2000Date of Patent: May 7, 2002Assignee: Eurodia Industrie S.A.Inventor: Roland Noel
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Patent number: 6224683Abstract: In demineralization of a beet sugar solution before boiling as the starting solution with a simulated moving bed chromatographic separator comprising a plurality of packed column units packed with a strongly acidic cation exchange resin in a salt form having an average grain size of 300 to 500 &mgr;m and a uniformity coefficient of at most 1.Type: GrantFiled: October 4, 1999Date of Patent: May 1, 2001Assignee: Organo CorporationInventors: Kouji Tanikawa, Fumihiko Matsuda, Kikuzo Kaneko, Makoto Tomizawa, Takayuki Masuda
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Patent number: 6200390Abstract: A “block” of betaine is displaced from the circulation loop of an ion exclusion system configured as an SMB without disturbing the normal operation of the system. In practice, a betaine-concentrated fraction is withdrawn (17) from the circulating loop of the SMB while an equal volume of water is introduced (15) to the loop. The circulation loop thereby continues without disruption.Type: GrantFiled: September 14, 1999Date of Patent: March 13, 2001Assignee: Amalgamated Research, Inc.Inventors: Michael M. Kearney, Kenneth R. Peterson, Michael W. Mumm
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Patent number: 6187204Abstract: The invention relates to a method for the fractionation of molasses using a chromatographic simulated moving bed system in which the liquid flow is effected in a single direction in a system comprising at least two chromatographic partial packing material beds. In the method of the invention, the product or products are recovered during a multi-step sequence comprising the following phases: feeding phase of molasses, eluting phase and recycling phase. The liquid present in the partial packing material beds with their dry solids profile is recycled in the recycling phase in a loop comprising one, two or several partial packing material beds.Type: GrantFiled: August 13, 1999Date of Patent: February 13, 2001Assignee: Danisco Finland OyInventors: Heikki Heikkild, Göran Hyöky, Jarmo Kuisma