Abstract: A non-nicotine e-vaping device may include a non-nicotine pod assembly and a device body. The non-nicotine pod assembly has upstream and downstream ends and is configured to hold a non-nicotine pre-vapor formulation. The upstream end may define at least one upstream recess, and the downstream end may define at least one downstream recess. The device body defines a through hole configured to receive the non-nicotine pod assembly. The through hole includes an upstream sidewall and a downstream sidewall. The upstream sidewall may include at least one upstream protrusion, and the downstream sidewall may include at least one downstream protrusion. The at least one upstream protrusion and the at least one downstream protrusion may be configured to engage with the at least one upstream recess and the at least one downstream recess, respectively, so as to retain the non-nicotine pod assembly within the through hole of the device body.

Abstract: Dry powder inhalers are described. The dry powder inhaler includes an air inlet, a reservoir and an airway assembly. A mouthpiece airway is connected to a first airway of the airway assembly. An airway head is attached to the airway assembly and it extends into the reservoir cavity. In certain embodiments, the airway head has a sharpened or beveled edge. At least one airway assembly opening is present in the airway assembly for connecting the reservoir cavity to the first airway. Methods for dispensing dry powder into an airway of a dry powder inhaler and inhaling dry powder from a dry powder inhaler is also disclosed. Embodiments of a dry powder inhaler having a two-stage air movement are also described.

Abstract: The invention relates to a device for olfactory stimulation of a patient with a plurality of scents, said device comprising: —a source (2) of a carrier gas (G); —a plurality of scent odorization circuits, each odorization circuit (4) comprising: —a container (18) containing an odorous volatile substance (V), —a container inlet line (26), provided with a container inlet valve (28), connecting an inlet (30) of said container with said source of carrier gas, and —a container outlet line (36), provided with a container outlet valve (38), connecting an outlet (40) of said container with an exit line (12); —a control unit (8), configured to control said container inlet valve and container outlet valve according to a medical protocol.

Abstract: An adjustable tracheostoma valve includes a housing having a first opening that is adapted to open to a tracheostoma and a second opening that opens to ambient. The housing includes a lower housing portion defining the first opening and an upper housing portion movably attached to the lower housing portion and defining the second opening. A closure member is disposed in the housing and adapted to close the second opening. A flexible membrane includes a first region connected to the closure member and a plurality of spiral shaped legs extending from the first region and connected to the housing. The upper and lower housings are axially adjustable relative to one another to adjust an amount of air flow through the valve that would cause closure of the closure member. A heat and moisture exchanger is disposed in the housing between the first opening and the second opening.

Abstract: An access system has a scanner that scans a unique identifier to access a location. A display receives an input. An automated dispenser dispenses at least one scent on each hand of an individual responsive to a control signal. A processor controls access to the location. A memory stores a set of instructions that configures the processor to receive the unique identifier from the scanner, actuate the automated dispenser to dispense the at least one scent responsive to receipt of the unique identifier, receive the response input based on the scents detected by the individual of the at least one scent, determine a passing result or a failing result responsive to the received response input and an expected response based on the dispensed at least one scent, enable access to the location responsive to a passing result and deny access to the controlled access location responsive to a failing result.

Abstract: A rescue tube comprising a tube having a first and second end, a one-way valve and a ported double swivel elbow; wherein the one-way valve and ported double swivel elbow are connected to one another, and the one-way valve is attached to the tube.

Abstract: A mouthpiece for a handheld inhaler is disclosed. A housing of the mouthpiece includes an inlet, an outlet opening, and a channel extending through the housing connecting the inlet and the outlet opening for directing an aerosol from the inlet to the outlet opening. An anterior portion of the housing (4) is configured for placement in the mouth of a patient. The anterior portion of the housing is configured to direct the outlet opening upwardly in the patient's oral cavity when in the mouth of the patient. Other embodiments include an outlet opening placed closer to the upper side of the housing than to the lower side of the housing. Further, an inhaler having a mouthpiece is disclosed.

Abstract: A snow burial survival mask has an exhaust tube connected to a headgear. An intake port of the exhaust tube is positioned adjacent to a breathing portion of the headgear in order to intake exhaled carbon dioxide (CO2)-rich air. An air pump connected to the exhaust tube pump the exhaled air from the intake port to an exhaust port away from the user's face, extending survival time in a snow burial situation. At least one burial detection sensor such as a motion sensor, light sensor and/or CO2 sensor is configured to activate the air pump based on detection of a burial event.

Abstract: A valve structure for treating a patient suffering from obstructive sleep apnea is provided. The valve structure is connected to an air flow generator and connected to a mask that covers at least the nostrils of a patient. The valve structure includes a housing with an inlet pressure port connected to the air flow generator, and an ambient pressure port. Within the housing is an expiratory membrane, an expiratory valve seat, an inspiratory membrane, an inlet pressure valve seat, an inspiratory valve seat, and an inspiratory membrane segmentation structure configured to segment the movement of the inspiratory membrane into at least a first portion and a second portion. An expiratory valve in fluid connection with the inlet pressure port is formed by the expiratory membrane and the expiratory valve seat. An inlet pressure valve is formed by the inlet pressure valve seat and the first portion of the inspiratory membrane.

Abstract: An apparatus, module, methods and systems for automated, standardized assessment and analysis of a human olfactory system's odor detection ability as an indicator or predictor of cognitive impairment or change in cognitive health, and other health conditions such as diabetes. Notably, the present invention is operable for use across all age groups of humans and provides quantitative detection and analysis of a human olfactory system's detection ability compared to a relevant demographic population.

Abstract: Methods are provided for non-invasive early screening of a subject for a neurodegenerative disorder, by analyzing one or more parameters associated with the neurodegenerative disorder.

Abstract: The invention relates to a flow controlled valve system. The flow controlled valve may be incorporated into a pre-filled, small-volume nebulizer assembly with a T-connector. The flow controlled valve allows different airflow characteristics in each direction. The flow controlled valve also facilitates breathing physiotherapy by creating different airflow resistances during inhalation and exhalation.

Abstract: The invention relates to a method of identifying a fragrance sample using functional Magnetic Resonance Imaging to assess the ability of said fragrance sample to elicit a reward through the dopaminergic pathway; a fragrance sample identified by the method, and a method for preparing an accord or a fully formulated fragrance.

Abstract: A stabilizer arm for a BVM resuscitator and method of use is disclosed. The stabilizer arm provides necessary support to the reservoir bag to enable the user to exert downward pressure on the BVM resuscitator while simultaneously squeezing the reservoir bag, and creates force that is focused, directed, and realized at the mask of the assembly. Due to presence of stabilizer arm, this pressure pushes the facial mask downward to assist in forming a tight mask to face seal. The stabilizer arm may be internal, external or integrated into the reservoir bag wall of the BVM resuscitator and may be retro-fitted or original equipment manufactured. The external stabilizer arm may be designed to engage the outlet port neck of the BVM resuscitator with an open collar or a closed collar. The internal stabilizer arm may be configured to fit BVM resuscitators having single piece or multiple piece outlet valve design.

Abstract: The present invention comprises an insufflated air inlet (2a), an outlet (3a) for said insufflated air provided at the lower end of an air conveying tube (3) designed to penetrate the throat of the victim through the mouth, at least a first one-way valve (4) interposed between said air inlet (2a) and air outlet (3a) to allow the flow of air from said inlet (2a) to said outlet (3a) and prevent the flow of a fluid exhaled by the victim in the opposite direction, the body of said valve (4) including an outlet aperture (4a) for the exit of the fluid exhaled by the victim, and characterized in that the upper end of said insufflated air conveying tube (3) comprises a portion (3b) of tube (3) which is configured for internally receiving the body of said valve (4), the wall of said tube (3) including at least one outer hole (6) communicating with the aperture (4a) of the body of the valve (4) to allow discharging the fluid exhaled by the victim to the outside.

Abstract: A respiratory mask assembly for delivering breathable gas to a patient includes a frame having a main body and a side frame member provided on each lateral side of the main body. Each side frame member includes an integrally formed first connector portion. A headgear assembly is removably attachable to the frame. The headgear assembly has a second connector portion adapted to be removably coupled with the first connector portion provided on the frame. The second connector portion is manually movable to a releasing position to detach the headgear assembly from the frame. The headgear assembly is rotationally adjustable with respect to the frame.

Abstract: The present invention comprises an insufflated air inlet (2a), an outlet (3a) for said insufflated air provided at the lower end of an air conveying tube (3) designed to penetrate the throat of the victim through the mouth, at least a first one-way valve (4) interposed between said air inlet (2a) and air outlet (3a) to allow the flow of air from said inlet (2a) to said outlet (3a) and prevent the flow of a fluid exhaled by the victim in the opposite direction, the body of said valve (4) including an outlet aperture (4a) for the exit of the fluid exhaled by the victim, and characterized in that the upper end of said insufflated air conveying tube (3) comprises a portion (3b) of tube (3) which is configured for internally receiving the body of said valve (4), the wall of said tube (3) including at least one outer hole (6) communicating with the aperture (4a) of the body of the valve (4) to allow discharging the fluid exhaled by the victim to the outside.

Abstract: Aerosolizing delivery apparatuses can include cartridges configured to be detachably connected to a delivery device. The cartridges can include: a housing defining a reservoir and a cartridge outlet, the cartridge outlet configured to permit fluid communication between the reservoir and an exterior of the cartridge. A surface of the housing can be configured to define a bypass port between the housing and a surface of the delivery device when the cartridge is assembled with the delivery device.

Abstract: A mouth-to-mouth resuscitation device comprising a straight blow-in tube having a proximal side and a distal side, a filter and one way valve on the proximal side for receiving exhaled breath from a mouth of a rescuer, an opening at the distal side for delivering the exhaled breath into the throat of a victim, an inflatable bladder surrounding the straight blow-in tube which, when inflated, assumes a donut shape which has a diameter of about 1.5? to 2.5?, the bladder located on the straight blow-in tube between about 0.75? and 2.0? from the distal opening, an inflation tube in fluid communication with the inside of the inflatable bladder.

Abstract: A flow regulation vent includes a fixed portion adapted to engage a gas supply conduit and a spring force biased movable portion connected by a hinge to the fixed portion and flowingly connected to the pressurized gas supply. The fixed portion includes a gas flow orifice. The movable portion is pivotally movable between 1) a relaxed position, whereby at a specified minimum operating pressure, the movable portion is pivoted by the spring force away from the fixed portion to a position to establish a first gas washout flow area between the movable portion and the gas flow orifice; and 2) a fully pressurized position, whereby at a specified maximum operating pressure, the pressurized gas offsets the spring force to pivot the movable portion to a position adjacent the fixed portion to establish a minimum gas washout flow area between the movable portion and the gas flow orifice.

Abstract: Inhalant anesthetics are developed with a number of properties including rapid onset and recovery, controllability, and, ideally, a broad safety profile. The efficacy of these agents is measured by their ability to create anesthesia within the framework of the other desirable properties. The instant invention focuses on the dosage level where analgesia occurs but amnesia or lack of consciousness does not. In addition to identifying the dosage level where pain is sharply reduced or eliminated but awareness remains, a delivery system for safe and effective delivery of the agent is described.

Abstract: The apparatus is equipped with cover unit (1) fixed to a head portion of worker so as to cover at least the regions of nose and mouth of the worker, the cover unit capable of trapping the worker's breath. The cover unit has an exhaust opening and an air supply opening. Further, the apparatus is equipped with moisture recycle unit (2) fitted to the worker so as to simultaneously carry out the two processes consisting of the adsorption process of introducing moist air, effecting adsorption of the water contained in the air on an adsorbent and emitting dry air and the regeneration process of introducing dry air, effecting evaporation of the water adsorbed on the adsorbent into the dry air and emitting moist air. Still further, the apparatus is equipped with exhaust hose (3) connecting the exhaust opening of the cover unit to the moisture recycle unit and with air supply hose (4) connecting the moisture recycle unit to the air supply opening of the cover unit.

Abstract: A method for regulating gas flows into and out of a patient includes repetitively forcing respiratory gases out of the lungs. Respiratory gases are prevented from entering back into the lungs during a time between when respiratory gases are forced out of the lungs. Periodically, an oxygen-containing gas is supplied to the lungs.

Abstract: The present invention relates to a respiration valve (401) for performing respiration tests on e.g. humans, consisting of at least three ports, a first mouth port (402) and two breathing ports (403, 404). The breathing ports (403, 404) comprise pneumatic pinch valves consisting of a channel (101) with a flexible wall (201) to be used for the flow of material and molded as an integrated part of a surrounding chamber (102). The flexible wall (201) comprises two opposing angularly interconnected wall segments (202) which are angularly connected at interconnection points (203) and which flexible wall (201) is pinched by a pressure from fluid, such as air, introduced into the chamber (102). The cross sectional shape corresponds in one embodiment approximately to a elongated hexagon. The construction of the respiration valve (401) comprising these pneumatic pinch is valves enables a very small, light, hygienic, and safe yet inexpensive construction with a long life expectancy.

Abstract: A mouth-to-mouth resuscitation device comprising a straight blow-in tube having a proximal side and a distal side, a filter and one way valve on the proximal side for receiving exhaled breath from a mouth of a rescuer, an opening at the distal side for delivering the exhaled breath into the throat of a victim, an inflatable bladder surrounding the straight blow-in tube which, when inflated, assumes a donut shape which has a diameter of about 1.5? to 2.5?, the bladder located on the straight blow-in tube between about 0.75? and 2.0? from the distal opening, an inflation tube in fluid communication with the inside of the inflatable bladder.

Abstract: A cardiopulmonary resuscitation device that combines ventilation of a patient's lungs with chest compressions on the patient's sternum area. The device includes a self-inflating bag having an outlet port through which the content of the bag is forced when bag is compressed; target indicia on the bag to indicate the proper position of the bag on the patient's sternum area and to indicate the proper location on the bag for applying force to the top side thereof; a face mask for placement over the patient's mouth and nose; and a tube extending from the bag to the face mask. The device may include indicia for indicating the amount of pressure applied to the self-inflating bag, and a backboard including belt/motor structure for providing repeated and rapid chest compression and forced ventilation of the patient's lungs.

Abstract: A diaphragm valve is provided, in which there is improved sealing of a closing cover (15) against the valve housing (3). The seal includes a cylindrical sealing washer (25), which is connected to the valve housing (3) in one piece and into which a cylindrical wall section (18) of the closing cover (15) can be inserted with press fit.

Abstract: According to one aspect of the present invention, an aerosol inhalation system includes a first conduit member for delivering medication in the form of aerosol particles to a patient. The system also includes a first device in fluid communication with the first holding chamber for producing the aerosol particles and being sealingly yet releasably received within an adapter that forms an entrance into a first holding chamber. The adapter has a compressible material disposed thereon which is at least partially compressed by insertion of the first device to form the seal between the first device and the adapter, thereby creating a closed system that is therefore capable of delivering a fixed concentration of the medication to the patient due to a valve of the valve mechanism being closed when the patient inhales and the medication is delivered to the patient.

Abstract: In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

Abstract: An apparatus and system for transferring a liquid, such as a liquid anesthetic, from a reservoir to a machine while minimizing the release of the liquid to the surrounding environment. The apparatus can include a frame member defining a frame passage extending from a first end of the frame member to a second end of the frame member and a nozzle connected to the frame member. The nozzle can be moveable between a first position and a second position relative to the frame member, and can define a plug member configured to block the second end of the frame passage when the nozzle is in the first position. The apparatus can further include a biasing member connected to the frame member and the nozzle.

Abstract: In one embodiment, the invention provides a medical method for treating a person and comprises repeatedly compressing the person's chest. While repeatedly compressing the person's chest, the method further includes repeatedly delivering a positive pressure breath to the person and extracting respiratory gases from the person's airway using a vacuum following the positive pressure breath to create an intrathoracic vacuum to lower pressures in the thorax and to enhance blood flow back to the heart.

Abstract: The present invention pertains to a valved holding chamber suitable for use in an aerosol medication delivery system. The valved holding chamber includes a housing and a mouthpiece coupled to the housing. A one-way valve assembly is coupled to the housing, the mouthpiece, or both so that fluid flows in a first direction from the housing to the mouthpiece passes through the valve assembly but does not pass back into the housing. The valve assembly includes a conical flange disposed such that the conical flange tapers in the first direction to smooth the fluid flow in the first direction toward the patient. In a further embodiment, the mouthpiece includes an exhaust port defined in a conical collar portion of the mouthpiece, and an exhaust valve element is disposed over the exhaust port to provide a one-way flow of fluid from within the mouthpiece to ambient atmosphere via the exhaust port.

Abstract: The invention relates to the use of pressurised metered dose inhalers (MDIs) having part or all of their internal surfaces consisting of stainless steel, anodised aluminium or lined with an inert organic coating; and to compositions to be delivered with said MDIs.

Abstract: An arrangement and method is provided for controlling operational characteristics of medical equipment. A pressure sensor associated with the caregiver is arranged to sense changes in air pressure that correspond to breathing activity of the caregiver. The pressure sensor may comprise a neckband, headset, or the like. In the arrangement shown, a headset that is worn by the caregiver includes a disposable tube connected to a pressure transducer such that the pressure sensor senses changes in air pressure in the tube. An open end of the tube is positioned near the mouth of the caregiver to receive changes in airflow from the caregiver's mouth. The pressure sensor is in communication with a controller associated with the ventilator. The controller is arranged to control at least one operational parameter of the ventilator, such as the delivery of respiratory support to the patient pr actuation of an oxygen flush valve on the ventilator, based upon the changes in air pressure sensed by the pressure sensor.

Abstract: A method for regulating gas flows into and out of a patient includes repetitively forcing respiratory gases out of the lungs. Respiratory gases are prevented from entering back into the lungs during a time between when respiratory gases are forced out of the lungs. Periodically, an oxygen-containing gas is supplied to the lungs.

Abstract: A mouth to mouth resuscitator device for use by a rescuer for resuscitating a victim, the device comprising a sheet of flexible material having a top surface and an undersurface, the sheet forming a mouth opening, a hollow substantially rigid tube having an external surface, a first end, a second end and a tube length between the first and second ends, a tube passage aligned at least in part with the mouth opening, the tube extending from the undersurface of the sheet to the second end and a self closing one-way valve located within the tube passage to restrict flow from the second end to the first end of the tube and to allow flow from the first end to the second end when a rescuer exhales air into the mouth opening, wherein the external surface of the tube forms at least one recess at a location along the tube length, the recess for receiving a victim's teeth.

Abstract: A respiratory mask includes: a mask cap defining a chamber and a through-hole in fluid communication with the chamber; and a valve unit including a hollow valve body that projects in an axial direction from a periphery of the through-hole in the mask cap and that is formed with a valve seat which defines a valve opening in the valve body. The valve unit further includes an abutting plate that is securely connected to the valve body, and a single-piece elastic block body that is formed with a shoulder abutting sealingly against the valve seat, and that has a bottom end abutting against the abutting plate. The elastic block body is elastically compressible in the axial direction so as to be deformed in the axial direction to thereby space the shoulder apart from the valve seat when pressed by an external force.

Abstract: The present invention provides a sterilizing facemask with a multi-layer filter, which discloses a first sterilizing layer and a second sterilizing layer. The first sterilizing layer uses ultraviolet light or visible light in external light for providing hydroxyl free radicals to sterilize inhaled air. Because the second sterilizing layer is inside of the facemask, there is no light provided. The second sterilizing layer inactivates the enzyme of bacteria's sulfhydryl group to sterilize exhaled air. In addition, in accordance with types of germs carried by users, the material of the second sterilizing layer can be further modified to ensure that the exhaled air is sterilized.

Abstract: A sterilizing facemask with a multi-layer filter discloses a first sterilizing layer and a second sterilizing layer. The first sterilizing layer provides inhaled aseptic air such as using ultraviolet light or visible light in external light hydroxyl free radicals to sterilize. The second sterilizing layer provides exhaled aseptic air from human such as using inactivated the enzyme of bacteria's sulfhydryl group to sterilize. In addition, in accordance with types of germs carried by users, the material of the second sterilizing layer can be further modified to ensure that the exhaled air is sterilized.

Abstract: A device for manipulating intrathoracic pressures comprises a compressible bag structure, and an interface member coupled to the bag structure. A one way forward valve is coupled to the bag structure to permit respiratory gas to flow to the patient when the bag structure is compressed. A one way exit valve is employed to allow respiratory gases to be pulled from the person's airway upon decompression of the bag structure to produce a negative intrathoracic pressure.

Abstract: A system controls and manages administration of a therapeutic gas, such as NO, O2, or the like, to a patient. The system includes an equalizing valve and a reservoir.

Abstract: A metered dose spray device administers medicine contained therein to the buccal cavity within a user's mouth upon actuation of the device. A metered dose spray device comprising an insulin solution is also provided.

Abstract: In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

Abstract: In one embodiment, a method for modulating a person's autonomic function comprises interfacing a valve system to the person's airway, the valve system being configured to decrease or prevent respiratory gas flow to the person's lungs during at least a portion of an inhalation event. The person is permitted to inhale and exhale through the valve system, wherein during inhalation the valve system functions to produce a vacuum within the thorax to transiently decrease intrathoracic pressure and thereby modulate the person's autonomic function.

Abstract: In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

Abstract: In one embodiment, the invention provides a device for decreasing intracranial or intraocular pressures. The device comprises a housing having an inlet opening and an outlet opening that is adapted to be interfaced with a person's airway. The device further includes a valve system that is operable to regulate respiratory gas flows through the housing and into the person's lungs during spontaneous or artificial inspiration. The valve system assists in lowering intrathoracic pressures during each inspiration to repetitively lower pressures in the venous blood vessels that transport blood out of the head to thereby reduce intracranial or intraocular pressures.

Abstract: A cardiopulmonary resuscitation device and method that combines artificial, emergency ventilation of a patient's lungs with chest compressions on the patient's sternum area. The device includes a self-inflating bag having a top side, a bottom side, and an outlet port through which the content of the bag is forced when the top side of the bag is pushed toward the bottom side of the bag; target indicia on the self-inflating bag to indicate the proper position of the self-inflating bag on the patient's sternum area and to indicate the proper location on the self-inflating bag for applying force to the top side of the self-inflating bag; a face mask for placement over the patient's mouth and nose; and a tube extending from the outlet port of the self-inflating bag to the face mask.

Abstract: An inflatable resuscitation face mask comprising a top sheet joined to a bottom sheet to form an inflatable pocket which when inflated forms a raised body having an apex and a lower perimeter, wherein inflation means is provided on the mask and an opening at the apex allows air to be administered through the opening to an area underneath the inflated mask.

Abstract: A method for increasing circulation in a breathing person utilizes a valve system that is interfaced to the person's airway and is configured to decrease or prevent respiratory gas flow to the person's lungs during at least a portion of an inhalation event. The person is permitted to inhale and exhale through the valve system. During inhalation, the valve system functions to produce a vacuum within the thorax to increase blood flow back to the right heart of the person, thereby increasing cardiac output and blood circulation.

Abstract: A device for manipulating intrathoracic pressures comprises a compressible bag structure, and an interface member coupled to the bag structure. A one way forward valve is coupled to the bag structure to permit respiratory gas to flow to the patient when the bag structure is compressed. A one way exit valve is employed to allow respiratory gases to be pulled from the person's airway upon decompression of the bag structure to produce a negative intrathoracic pressure.