Abstract: According to an embodiment of the present disclosure, there is provided a laser spectroscopy-based independent device, including: a spectrometer configured to measure a spectrum of generated light which is generated by a laser projected onto a sample; and a disease analysis module configured to determine whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement, which is measured by the spectrometer, wherein the spectrometer is configured to measure spectra of all generated light that is generated from a time when the laser is projected onto the sample.

Abstract: Phase space tomography methods and systems to facilitate the analysis and evaluation of complex, quasi-periodic system by generating computed phase-space tomographic images and mathematical features as a representation of the dynamics of the quasi-periodic cardiac systems. The computed phase-space tomographic images can be presented to a physician to assist in the assessment of presence or non-presence of disease. In some implementations, the phase space tomographic images are used as input to a trained neural network classifier configured to assess for presence or non-presence of pulmonary hypertension, including pulmonary arterial hypertension.

Abstract: A system, device and method for automatically and remotely acquiring sensor data from a wearable patch mounted on a patient. An example device implemented as a wearable patch includes a sensor assembly comprising a plurality of sensors configured to detect a corresponding plurality of sensory modalities and generate electrical signals representing the sensory modalities. A signal converter receives the electrical signals from the plurality of sensors and converts the signals to sensor data signals comprising a data representation of at least one of the electrical signals. A communications interface communicates the sensor data signals to a sensor data processing system.

Abstract: A system for monitoring a patient during MRI imaging to prevent patient burns. The system includes a barrel to provide an MRI image of a patient and an infrared camera to image the patient separately from the MRI image. The infrared camera includes an adjustable field of view and is positionable at a plurality of viewing angles relative to the longitudinal axis of the barrel. The infrared camera is coupled to a processor adapted to monitor the surface temperature of the patient based on the output of the infrared camera. The processor is further adapted to control at least one of the field of view of the infrared camera and/or the viewing angle of the camera during MRI imaging of the patient. The system further includes a patient gown formed of an infrared transmissive material that provides visual concealment for the patient.

Abstract: A physiological information processing apparatus includes a processor and a memory storing computer-readable instructions. When the computer-readable instructions are executed by the processor, the apparatus obtains physiological information data indicative of physiological information of a subject, obtains RR interval data including a plurality of RR intervals based on the physiological information data, identifies an RR interval indicative of arrhythmia, and displays the RR interval data as plotted points on a two-dimensional coordinate system having one axis representing an n-th RR interval and another axis representing an (n+1)-th RR interval. The RR interval data is displayed on the two-dimensional coordinate system such that a visual mode of a plurality of first plotted points associated with the RR interval indicative of arrhythmia and a visual mode of plotted points of the RR interval data other than the plurality of first plotted points are different from each other.

Abstract: Intravascular devices, systems, and methods are disclosed. In some instances, the intravascular device is a guide wire having a polymer jacket applied over communication lines and a core member, where the communication lines have been wrapped around the core member. For example, in some implementations a sensing guide wire includes a proximal portion and a distal portion, the distal portion including: a core member; a plurality of communication lines wrapped around the core member; a polymer jacket formed around the core member and the plurality of communication lines; and a sensing element positioned distal of the polymer jacket and communicatively coupled to the plurality of communication lines. Methods of making, manufacturing, and/or assembling such intravascular devices and associated systems are also provided.

Abstract: A system and method are provided for tracking magnetically-labeled substances, such as transplanted cells, in subjects using magnetic resonance imaging (MRI).

Abstract: In some examples, a processor determines a patient state based on activity of a bioelectrical brain signal of a patient in one or more frequency sub-bands of a frequency band of interest. For example, a processor may determine a patient state based on the power level of a bioelectrical brain signal of the patient in one or more frequency sub-bands of a frequency band, or based on a spectral pattern of a bioelectrical brain signal in a frequency band, such as a shift in a power distribution between sub-bands, a change in the peak frequency within one or more sub-bands, a pattern of the power distribution over one or more frequency sub-bands, or a width or a variability of one or more sub-bands exhibiting a relatively high or low level of activity.

Abstract: A surgical instrument for assessing tissue characteristics such as tissue density and volume is disclosed. The surgical instrument is hand-held and includes transducers adapted for emitting and/or receiving acoustic signals. The surgical instrument utilizes pulse-echo to determine tissue characteristics. The surgical instrument may be utilized to determine such things as the size of a lesion and whether the lesion has been completely removed or filled with graft material.

Abstract: An apparatus for non-invasively estimating a biological component is provided. The apparatus may include: a sensor configured to measure a calibration spectrum for a first duration and measure a biological component estimation spectrum for a second duration, based on light returning from an object; and a processor configured to remove a signal of a biological component from the calibration spectrum to obtain a background spectrum for the first duration, and estimate the biological component, based on the background spectrum and the biological component estimation spectrum, for the second duration in response to a command for measuring the biological component.

Abstract: A surgical instrument includes a rotatable electrical coupling assembly having a first part and a second part that electrically couple and rotate relative to each other. The second part is carried by and rotates with a tube collar coupled to a transducer. A portion of the transducer is inserted through an aperture of the second part, but does not contact the second part. The first part of the assembly may electrically couple to the second part via pogo pins, brush contacts, or ball bearings. Alternatively, the first part may comprise conductive channels formed in the casing. The second part may comprise a rotatable drum with a conductive trace. In some versions, one or more components may comprise MID components. In another version, the rotatable electrical coupling assembly comprises a rotatable PC board and brush contact. Further still, a circuit board may be provided with the transducer inside a transducer casing.

Abstract: A surgical shaft assembly includes a slip ring assembly. The slip ring assembly has a first connector, a first conductor mounted on the first connector, and a first water-proof insulative layer on the first conductor. The slip ring assembly has a second connector rotatable relative to the first connector, a second conductor mounted on the second connector, and a second water-proof insulative layer on the second conductor. The slip ring assembly also has a dielectric layer located between the first water-proof insulative layer and the second water-proof insulative layer. The first conductor and the second conductor are configured to form a capacitive channel therebetween.

Abstract: A method and system for generating pulse oximetry predictive scores for predicting adverse outcomes in preterm infants.

Abstract: A control device 60 of a vehicle drive device comprises a processing part 81 configured to use a trained model using a neural network to calculate at least one output parameter of a vehicle, and a control part 82 configured to control the vehicle drive device. The neural network includes a first input layer to which at least one first input parameter of the vehicle at a first point of time is input, a second input layer to which at least one second input parameter of the vehicle at a second point of time is input, a first hidden layer to which outputs of the first input layer are input, a second hidden layer to which at least one value correlated with the outputs of the first hidden layer, and outputs of the second input layer are input, and an output layer outputting at least one output parameter.

Abstract: A way of indicating a risk for coronary artery disease is disclosed. A first plurality of first sound recordings of heartbeats and second plurality of second sound recording of the ambient background are obtained. A filtering of each first sound recording is performed by using a simultaneously recorded second sound recording. The filtering of each first sound recording involves determining a diastolic period of the heartbeat of the first sound recording, and performing an adaptive filtering of the first sound recording based in the diastolic period of the first sound recording and the simultaneously recorded second sound recording. This is followed by determination of an indication of the risk for coronary artery disease based on the filtered first sound recordings.

Abstract: A method for generating an automated test configured to test a system under test. The system under test has a plurality of operational states, at least one operational state having one or more executable actions associated therewith operable to execute predetermined operations and/or transition the system under test between operational states. The method includes the steps of: defining a model of the system under test comprising a plurality of model states; defining one or more selectable model actions; associating one or more test description sections with one or more model actions; selecting a sequence of model actions; and utilising the test description sections associated with the selected sequence of model actions to define a sequence of operation commands for execution on the system under test as an automated test.

Abstract: A method for defining an automated test is configured to test a system under test. The system under test includes a plurality of operational states, at least one operational state having executable actions associated therewith operable to execute predetermined operations and/or transition the system under test between operational states. The method includes a) defining an executable model of the system under test including a plurality of model states; and b) defining one or more selectable model actions, each model action representative of one or more executable actions on the system under test and configured such that one or more preconditions are assignable thereto. Each model action is configured to be available to be selected unless any preconditions assigned to the respective model action are not satisfied. The model is configured such that a test program is operable to select a sequence of available model actions to define an automated test.

Abstract: Techniques that facilitate monitoring learning performance using neurofeedback are described. In one embodiment, a system is provided that comprises a memory that stores computer-executable components and a processor that executes computer-executable components stored in the memory. In one implementation, the computer-executable components comprise a feedback component that receives first feedback information regarding mental function of a user in association with participation in a learning experience, wherein the first feedback information is captured via a NIRS spectroscopy sensor worn by the user.

Abstract: Systems and methods are disclosed for determining physiological information in a subject. The system includes: a light source positionable along a first location outside of the subject; a photo-sensitive detector positionable along a second location outside of the subject and configured to detect scattered light and generate a signal; a processor having a program and a memory, wherein the processor is operably coupled to the detector and configured to receive and store the signals generated over a period of time; wherein the processor is programmed to derive contrast metrics from the stored signals, calculate a waveform from the contrast metrics, decompose the waveform into basis functions and respective amplitudes, and compare the basis function amplitudes to determine the physiological information.

Abstract: A tissue staining method which comprises: staining a tissue with a staining reagent wherein a biosubstance recognition site is bonded to particles carrying multiple fluorescent substances accumulated therein; in the stained tissue, counting fluorescent points or measuring fluorescent brightness; and evaluating the expression level of a biosubstance, which matches the biosubstance recognition site, in the aforesaid tissue on the basis of the number of the fluorescent points or fluorescent brightness that was measured.

Abstract: An ultrasonic diagnostic device according to an embodiment includes an ultrasonic probe and transformer circuitry. The ultrasonic probe transmits ultrasonic waves to a subject and converts reflection waves reflected by the subject to a reflection wave signal. The transformer circuitry includes an auto transformer that transforms the reflection wave signal at a transformation ratio in accordance with a control signal based on information related to the ultrasonic probe among a plurality of transformation ratios.

Abstract: An apparatus including at least one of a stainer module and a coverslipper module; an imaging module; a storage module; an automated transport module for transporting at least one slide between at least one of the stainer module and the coverslipper module, the imaging module and the storage module; and a controller. A method including processing at least one slide; determining whether an imaging module is available for imaging of a biological specimen on the at least one slide; transporting the at least one slide to the imaging module using an automated transport module; and transporting the at least one slide to a storage module using the automated transport module when it is determined that the imaging module is not available. A system including a processing module for processing at least one slide including a biological specimen thereon. A machine readable medium.

Abstract: A ballistocardiographic method and monitoring system calculates an indicator of the average heart rate of a test subject within a time interval. The test subject may be a fetus inside a mother's belly, or infant lying in the same bed as an adult. The monitoring system comprises a recoil surface and an acceleration sensor in contact with the recoil surface. A control unit identifies in the time domain the characteristics of the adult's heartbeat during the time interval. The output signal is then transformed to the frequency domain across the time interval and the signal is screened with the adult heartbeat characteristics. The indicator is then calculated from the screened signal in the frequency domain. The control unit monitors the indicator of the infant or fetus heart rate and may provide an alert if the indicator value drops very rapidly, or falls below a predetermined threshold value.

Abstract: Embodiments of the invention provide a neurosynaptic system comprising a delay unit for receiving and buffering axonal inputs, and a neural computation unit for generating neuronal outputs by performing a set of computations based on at least one axonal input received by the delay unit. The system further comprises a permutation unit for receiving external inputs to the system, and transmitting external outputs from the system. The permutation unit maps each external input received as either an axonal input to the delay unit or an external output from the system. The permutation unit maps each neuronal output generated by the neural computation unit as either an axonal input to the delay unit or an external output from the system. The neural computation unit comprises multiple electronic neurons, multiple electronic axons, and a plurality of electronic synapse devices interconnecting the neurons with the axons.

Abstract: An input device includes a housing, an operation unit, a vibrating body, a piezoelectric element, a picker, and a signal processing unit. The operation unit is movable relative to the housing. The vibrating body has elasticity. The vibrating body includes a first end partially fixed to the housing, and a second end provided so as to be vibratable. The piezoelectric element is provided to the vibrating body. The piezoelectric element is configured to convert vibration energy of the vibrating body into electrical energy as the vibrating body vibrates. The picker flicks the vibrating body to allow the vibrating body to vibrate in conjunction with the operation unit. The signal processing unit is configured to receive power generated by the piezoelectric element to operate and transmit, through wireless communications, detection information to be generated as the operation unit moves.

Abstract: A physical activity consumption amount calculation unit calculates the consumption amount of physical activity, which is the amount of physical activity consumed by a subject, from biological information acquired by a biological information acquisition unit. A recovery amount calculation unit calculates the amount of recovery, which is the amount of physical activity recovered by the subject, from the biological information acquired by the biological information acquisition unit. A retained physical activity amount calculation unit calculates the amount of retained physical activity, which is the amount of physical activity retained by the subject, from the reference amount of physical activity set by the reference physical activity amount setting unit, the consumption amount of physical activity calculated by the physical activity consumption amount calculation unit, and the amount of recovery calculated by the recovery amount calculation unit.

Abstract: An oscilloscope including an input port for receiving training data including waveforms and corresponding known classifications and a processor for training a plurality of classifiers on the training data. Training includes iteratively applying each classifier to each waveform of the training data to obtain corresponding predicted waveform classifications and comparing the predicted waveform classifications with the known classifications. Classifiers are corrected when predicted waveform classifications does not match the known classifications. Models for each classification are constructed with suggested measurements or actions. Subsequently, live waveform data is captured by the oscilloscope and the classifiers are applied to the live data. When a confidence value for a single classification exceeds a threshold, the waveform data is classified, and suggested measurements or actions are implemented in the oscilloscope based on the classification.

Abstract: Accurate and effective methods for measuring cardiovascular and respiratory parameters are provided. The method for deriving a depth-specific photoplethysmography (PPG) signal from multi-wavelength PPG signals includes choosing light wavelength combinations, calibrating a multi-layer light-tissue interaction model referring to a physiological signal, and generating the depth-specific PPG signal from the multi-wavelength PPG signals based on the calibrated light-tissue interaction model. The disclosed method for cuff-less blood pressure measurement includes recording a physiological signal and multi-wavelength PPG signals of a predetermined body part, deriving the depth-specific PPG signal reflecting the arterial blood volume with the physiological signal as a reference, calculating the pulse transit time (PTT) from the physiological signal and the derived arterial blood PPG signal, and calculating the blood pressure from the calibrated PTT and blood pressure relationship.

Abstract: Devices and methods for determining the position of a device relative to a person using the device, or the position of a part of a user's body relative to the user. One or more thermal sensor may be used to determine the relative position of the device or part of the user's body.

Abstract: Methods and systems for medical diagnosis by machine learning are disclosed. Imaging data obtained from different medical techniques can be used as a training set for a machine learning method, to allow diagnosis of medical conditions in a faster a more efficient manner. A three-dimensional convolutional neural network can be employed to interpret volumetric data available from multiple scans of a patient. The imaging data can be analyzed in real-time to prescribe additional testing while the patient is still within the medical facility.

Abstract: Disclosed herein is a system and method that can be used with any underlying classification technique. The method takes into account both the value of the current feature vector. It is based on evaluating the effect of perturbing each feature by bootstrapping it with the negative samples and measuring the change in the classifier output. To assess the importance of a given feature value in the classified feature vector, a random negatively labeled instance is taken out of the training set and replaces the feature at question with a corresponding feature from this set. Then, by classifying the modified feature vector and comparing its predicted label and classifier output a user is able measure and observe the effect of changing each feature.

Abstract: Provided are a method and systems for performing pulse oximetry. A light signal is emitted for a period of time and a modulated light signal is detected. The modulated light signal includes a red signal and an infrared signal. The modulated light signal is originated by an interaction of the light signal with a pulsatile tissue and a non-pulsatile tissue. The modulated light signal is processed to estimate an oxygen saturation in the pulsatile tissue during the period of time. The processing includes removing a non-pulsatile component resulting from the interaction of the light signal and the non-pulsatile tissue. The non-pulsatile component can be removed by removing a first parameter from an intensity of the infrared signal and a second parameter from an intensity of the red signal. The parameters are pre-determined using a calibration process to reproduce a true value for a ratio used to determine the oxygen saturation.

Abstract: Embodiments of the present invention disclose a method, a computer program product, and a computer system for ranking inclusion and exclusion criteria based on problematic language. A computer receives criteria and identifies semantic entailment between two or more criteria. The computer further identifies inclusionary criteria that appear as exclusionary criteria and exclusionary criteria that is difficult to interpret. The computer additionally identifies criteria having hypothetical, time specific, or complex language. Based on the computer identifying inclusionary criteria that appears as exclusionary criteria, exclusionary criteria that is difficult to interpret, or criteria having hypothetical, time specific, or complex language, the computer ranks the subject criteria based on the identified problematic language and presents the ranked criteria.

Abstract: A system is disclosed using a data-driven approach to objectively measure the diagnostic accuracy and value of diagnostic imaging reports using data captured routinely as part of the electronic health record. The system further utilizes the evaluation of the diagnostic accuracy of individual radiologists (imagers), subspecialty sections, modalities, and entire departments based on a comparison against a “precision diagnosis” rendered by other clinical data sources such as pathology, surgery, laboratory tests, etc.

Abstract: A density region setting unit sets a specific density region having a preset width with respect to a subject region of a radiation image. A compression processing unit performs a dynamic range compression process with respect to the radiation image on the basis of a first compression amount for compressing at least one of the maximum value or the minimum value among pixel values of the subject region into the specific density region and a preset second compression amount for compressing at least one of a high-density region or a low-density region in the specific density region, to generate a dynamic range compression image.

Abstract: A method of classifying a signal waveform under test for appropriate numerical measurement includes acquiring waveform data indicative of the signal waveform under test, analyzing the waveform data, determining a signal waveform type from the analyzed waveform data, and activating an appropriate numerical measurement of the signal waveform under test based upon the determined signal waveform type. There is also provided a test and measurement instrument configured to carry out any of the disclosed methods.

Abstract: A method for use in medical imaging of a patient including, with the patient immobilized with respect to an imaging reference frame, acquiring first digital imaging information including a first region of interest using a first imaging modality; processing the first digital imaging information to identify a feature for analysis; and using a second imaging modality to acquire targeted second imaging information for a second region of interest, the second region of interest corresponding to a subset of the first region of interest, wherein the second region of interest includes the feature for analysis.

Abstract: A system for human-digital media interaction tracking. One example system includes a database that stores information regarding a user's activity history for various different cognitive tasks, and a computing device that receives user behavior information indicating usage by a user of an interactive software program, the interactive software program associated with at least one of the cognitive tasks. The computing device, in response to the receipt of user behavior information indicating usage by the user of the interactive software program, updates the database information regarding the user's activity history for the at least one of the cognitive tasks.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: The invention subject of the application is related to a system which detects movements performed by the hand and converts them to text and/or audio and is comprised of a pair of gloves and at least one data processing module developed to convert sign language used by hearing/speech impaired individuals to spoken language and/or text or to convert hand gestures defined for a particular purpose to audio and/or text.

Abstract: A front-end system collects diagnostically relevant information or data, including pulse waveform information, and optionally timing information, symptom information, and/or diagnostic information. One or more sensors or transducers detect pulse waveforms in a consistent manner, across various subjects and practitioners. A back-end system stores diagnostically relevant information and diagnostic information, typically for a large population of subjects and practitioners. The back-end system generates system generated diagnoses and/or suggested remedial actions based on submitted inquiries or requests. The back-end system can advantageously employ machine learning techniques to identify correlations between defining characteristics or features of pulse waveforms and diagnoses, over a large number of samples submitted by a substantial number of practitioners, for instance of traditional Chinese medicine. The back-end system can also employ primary and/or secondary symptoms in identifying correlations.

Abstract: Systems, devices and methods are described for mounting medical equipment on IV poles, bed rails and other supporting structures in medical facilities including operating rooms and critical care sections. A system including a mounting hanger and corresponding equipment housing is disclosed that allows quick mounting and dismounting of equipment from a supporting structure. The novel structural design of mounting hanger including a symmetrical t-slot feature and a plunger lock allows a piece of equipment to be mounted on a supporting structure in multiple orientations as per the requirement which allows a user to optimize the placement of equipment in the medical environment.

Abstract: A programming equipment (1) for programming (fitting) of a programmable hearing aid (2) comprises means for receiving information on the state of operation of signal processing systems included in the hearing aid. This information is utilized to present a graphical representation of the state of operation of these systems to the person performing the programming. The invention further provides a hearing aid and a method of programming a hearing aid.

Abstract: The present disclosure provides methods of decoding speech from brain activity data. Aspects of the methods include receiving brain speech activity data from a subject, and processing the brain speech activity data to output speech feature data. Also provided are devices and systems for practicing the subject methods.

Abstract: Technologies for detecting a physical assault against a user include one or more clothing sensor modules coupled to a garment of the user. Each clothing sensor module is configured to produce sensor data indicative of the removal of the garment from the user and determine whether a physical assault is presently occurring against the user using an assault detection model with the sensor data as an input to the assault detection model. In response to a determination of the physical assault against the user, the clothing sensor module is configured to alert a trust party.

Abstract: A system and method for pre-operatively optimizing a fit of an orthopedic implant relative to a particular individuals anatomy is provided.

Abstract: In tomosynthesis imaging for obtaining a tomographic image from a plurality of projected images, in a case where a reconstruction condition and the tone conversion condition have been changed, control is performed to determine whether or not to use the changed tone conversion condition for tone conversion processing to be performed on a tomosynthesis image reconstructed in accordance with the changed reconstruction condition.

Abstract: This disclosure relates generally to health management, and more particularly to a method and system for artificial intelligence based diagnostic and prognostic health management of host systems. In an embodiment, the system includes a memory to store instructions, and a neural network controller coupled to the memory. The neural network controller is configured by the instructions to monitor a plurality of unique patterns generated in real-time. The plurality of system parameters is indicative of a system-level performance of the host system. The neural network controller is configured by the instructions to compare the plurality of unique patterns with a plurality of predetermined patterns corresponding to the plurality of system parameters to detect potential anomalies in the host system and one or more subsystems of the plurality of subsystems, where the one or more subsystems are responsible for contributing to the potential anomalies in the host system.

Abstract: An article of handwear for grasping a medical device in a medical environment includes a base adapted to be worn by a hand of a wearer. A sensor assembly is carried by the base. The sensor assembly is adapted to sense a force applied by the hand of the wearer, via the article of handwear, to the medical device. The sensor assembly is adapted to provide information regarding at least one shear component of the forces sensed by the sensor assembly.

Abstract: A system and methods for detecting particles and soluble chemical entities in body fluids consists of a system consisting of a microscopic apparatus, a sample chamber and reagents and methods used to detect, classify and enumerate particles and chemical entities in body fluids. Body fluids containing particles combined with reagents sediment to the bottom of a viewing chamber bringing them into the focal place of a digital microscopic detector. Particles identified as areas within a captured digital image that absorb or emit electromagnetic radiation can be further classified based on additional absorbed or emitted electromagnetic radiation within the predefined areas of the first digital image. Soluble chemical entities in body fluids are detected and concentrations determined using transmitted or emitted electromagnetic radiation using known chemical or antibody reactions, making the microscopic device a general purpose detector for in vitro determinations using body fluids.