Pressure Infusion Patents (Class 128/DIG12)
  • Patent number: 5006112
    Abstract: To prevent engagement and disengagement of the drive elements of a syringe pump, a clutch element (17) is used which permanently engages with the screw spindle (14). The clutch element (17), which may be formed of two cog wheels (18a, 18b) or of a nut, is alternatively blocked or released by brake elements (21). The brake elements are actuated by an actuation button (9) via a brake tube (15) and a pivoting lever (24). Since the clutch element (17) is permanently engaged to the screw spindle (14) there is no mechanical play upon initiation of the dispensing process.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: April 9, 1991
    Assignee: MTS Schweinfurt GmbH
    Inventor: Dieter Metzner
  • Patent number: 5002055
    Abstract: An apparatus for the biofeedback control of body functions is proposed having at least one sensor for detecting biological body functions, a data memory for storing comparison values, a control unit or microprocessor (9, 16) and a therapy member, the control means (9, 16) activating the therapy system as a function of the measured values detected by the sensor and the comparison values. The therapy systems has a pump for the intravenous, intra-arterial, oral or intraluminal administration and a drug reservoir connected to the pump. The control unit and/or therapy means is provided with a memory, which stores the therapy objectives for the body functions with associated drug doses as a function of the detected measured values and comparison values.
    Type: Grant
    Filed: September 30, 1988
    Date of Patent: March 26, 1991
    Assignee: Mic Medical Instruments Corporation
    Inventors: Hans S. Merki, Rolf-Rainer C. Dries
  • Patent number: 5000739
    Abstract: A programmable pump with three separate components: a driver, a reservoir and a tubing set connector. The driver provides an electromechanical assembly causing fluid to flow from the reservoir. The driver can be programmed for varying flow rates and alternating on/off delivery cycles through the control of switches externalized on the driver face. The reservoir is designed as a separate component. The driven side of the reservoir is the bottom. The top of the reservoir includes a port, and the bottom includes a septum for filling by a needle. The tubing set connector subsequently mounts into the port connector of the reservoir. The tubing set connector provides the interface to any standard luer-type tubing set which then connects to a needle for infusion. The circuitry is hardware logic programmable circuitry.
    Type: Grant
    Filed: July 12, 1988
    Date of Patent: March 19, 1991
    Assignee: Pinewood Medical, Inc.
    Inventors: Andrzej Kulisz, Robert Kendig, Jeffrey Williams
  • Patent number: 4998570
    Abstract: A filling device for filling an injection syringe is provided which enables the user to count the intake dosage by means of a sound indicator which may be mechanical, electrical or an electronic sound device. The filling device includes a moveable syringe holder to which is attached a removable syringe that is connectable to a medicinal bottle. The filling device mounts a gear which is moveable one notch at a time to actuate a linear gear to which the syringe is mounted. The device is connected to a microprocessor controlled voice chip device to obtain a suitable voice readout indicating the amount of liquid medicinal uptake by the syringe.
    Type: Grant
    Filed: November 22, 1989
    Date of Patent: March 12, 1991
    Assignee: Pavel Jordan & Associates
    Inventor: Bernard Strong
  • Patent number: 4997420
    Abstract: A portable drug delivery device for delivering a drug in liquid or fluid form at a constant and self-regulated rate to a patient comprises a syringe having spring loaded piston reciprocal in a cylinder having a reverse taper to pressurize the drug to be dispensed. The reverse taper on the cylinder results in decreasing friction on the piston as the piston moves in the cylinder during a dispensing cycle, and is designed to compensate for the decreasing force exerted on the piston by the expanding spring. A length of tubing connected to the syringe conveys the drug to a needle or other device for administering the drug to a patient, and a restrictor in the length of tubing impedes flow of the drug to achieve a desired flow rate. The restrictor may be sized to achieve any desired flow rate, and in a preferred form of the invention comprises a laser-burned hole in a fitting attached to the outlet end of the length of tubing.
    Type: Grant
    Filed: December 28, 1989
    Date of Patent: March 5, 1991
    Inventor: Robert J. LeFevre
  • Patent number: 4995432
    Abstract: Dosage equipment, which includes a peristaltic pump for the dosage of liquid. The set of hoses (17) of the peristaltic pump includes an upper piece (18) and a lower piece (19). The body of the pump includes an attaching piece (13), to which the upper piece and the lower piece can be attached.
    Type: Grant
    Filed: October 13, 1988
    Date of Patent: February 26, 1991
    Assignee: Labsystems Oy
    Inventors: Jukka Tervamaki, Mauno Heinonen, Matti Priha, Juha Koivisto
  • Patent number: 4988337
    Abstract: Disclosed is a syringe pump apparatus adapted to have a syringe mounted thereon so as to supply in a specified amount per specified unit of time an aqueous solution such as medication within the syringe. A first shaft is fixed to a slider for causing a piston portion of the syringe to operate. Between this slider and a drive motor there are provided a block and a second shaft, the block being provided with an overload detecting mechanism. When the movement of the slider is forcedly stopped during a time period in which the slider is being moved through driving of the drive motor, the resulting load is transmitted to the first shaft in response to the forced stoppage of the slider. In accordance with this load, the overload detecting mechanism detects the state of overload of the slider. Then, when the value detected has exceeded a specified value, the drive motor is stopped by a drive halting mechanism.
    Type: Grant
    Filed: August 8, 1989
    Date of Patent: January 29, 1991
    Assignee: Terumo Kabushiki Kaisha
    Inventor: Yoshio Ito
  • Patent number: 4976696
    Abstract: A syringe pump comprises a housing and a retainer mounted thereon for receiving a syringe. The syringe to be received is of the type including a barrel for holding liquid medication and a plunger movably positioned in the barrel for expelling the liquid medication therefrom. A driver is movably mounted on the housing for engagement with the plunger and for pushing the plunger into the barrel to thereby force the liquid medication out of the barrel. A control mechanism within the housing regulates the movement of the driver against the plunger. This thereby regulates delivery of the liquid medication from the barrel. Depressible actuation buttons or switches are mounted on the housing for manual access by a user. These switches are associated with the control mechanism to permit the user to select one or more functions under which the control mechanism is to operate. The actuation switches include an electrically conductive material positioned to contact the control mechanism when depressed by the user.
    Type: Grant
    Filed: June 16, 1989
    Date of Patent: December 11, 1990
    Assignee: Becton, Dickinson and Company
    Inventors: George Sanderson, Robert J. Strowe
  • Patent number: 4969873
    Abstract: Septum for implantable devices for dispensing active substances, for example medicaments, to the body of the patient. The septum is inserted as a cover of a medicament chamber into the associated opening by means of one or more clamping members, the septum (22; 36; 10) being formed annularly with part (32) of the apparatus wall disposed within the septum and connected fixedly to the remaining housing (31).
    Type: Grant
    Filed: June 22, 1989
    Date of Patent: November 13, 1990
    Assignee: Annemarie Schlogl Gesellschaft m.b.H. & Co., KG
    Inventors: Bernd Steinbach, Leopold Schlogl
  • Patent number: 4968301
    Abstract: A disposable IV infusion device for ambulatory patients comprises a disk-shaped cover plate and a disk-shaped impeller plate which are interconnected by a stretched membrane that joins the edge of the cover plate with the edge of the impeller plate. The effect of the membrane is to urge the plates into juxtaposition. A fluid port is formed on the cover plate for fluid communication through the port with a collapsible fluid chamber established between the plates. Fluid, when injected into the chamber between the plates, is subsequently expelled through the port for controlled infusion to a patient as the membrane pulls the plates toward each other to collapse the chamber.
    Type: Grant
    Filed: February 2, 1989
    Date of Patent: November 6, 1990
    Assignee: Imed Corporation
    Inventors: Giorgio di Palma, Victor L. Bartholomew
  • Patent number: 4955860
    Abstract: Volumetric pump for use in the parenteral perfusion of solutions without the need for the substitution or inclusion of additional elements in traditionally used dropper systems. The pump consists of a rigid chamber (1) containing a bag (2) with the solution to be perfused and is set up in a common volume formed by a liquid or gaseous interface with another chamber (3) to which it is connected, acting as a pump or pumping agent, and equipped with a distendable membrane (4), which acts on the walls of the bag (2), extracting the residual air by means of suction through the duct (8) which has a valve (5). The solution then passes through a connection tube (6) and is perfused. There is a stopcock (7) in the passage connecting the compartments (1) and (3), and the system is equipped with timers (9) which enable the selected flow to be determined and a servomechanism (10) to ensure greater precision.
    Type: Grant
    Filed: April 11, 1988
    Date of Patent: September 11, 1990
    Inventor: Miguel M. Ruano
  • Patent number: 4954046
    Abstract: A linear peristaltic pump includes a mechanism for maintaining linear flow of fluid through an I.V. tube. The mechanism comprises a casing carrying a rotatable camshaft having a plurality of cams spaced therealong in helical arrangement and a plurality of fingers coupled to the camshaft. A housing for establishing linear reciprocal movement of the fingers in response to rotation of the shaft establishes a moving zone of occlusion along a tube held against the fingers. Aligning means are included for establishing an axis of rotation of the camshaft which is slightly tilted with respect to the tube. This is accomplished by raising or lowering the upstream or the downstream end of the camshaft to prevent unwanted pressure from building up in the tube to reduce pulsatile flow and maintain linear flow. The aligning mechanism comprises a generally cylindrical bushing having an eccentric hole therethrough for carrying the hinged connection between the casing and the housing.
    Type: Grant
    Filed: December 8, 1989
    Date of Patent: September 4, 1990
    Assignee: IMED Corporation
    Inventors: Ronald D. Irvin, David Burkett, David E. Kaplan, Ronald J. Harvey
  • Patent number: 4952124
    Abstract: A medicine injector includes a finger pump which comprises an injection tube containing a liquid medicine and a plurality of fingers adapted to move in a specified sequence to compress this tube. The widths of these fingers are effectively varied by simultaneously compressing the tube with specified two or more of these fingers. This has the effect of increasing the amount of liquid which can be ejected out of the tube and to minimize the effects of a backflow.
    Type: Grant
    Filed: March 24, 1986
    Date of Patent: August 28, 1990
    Assignee: Sharp Kabushiki Kaisha
    Inventor: Mitsuji Ogami
  • Patent number: 4950245
    Abstract: A pump housing which contains a plurality of linear peristaltic pumps and receives a fluid source cartridge. The cartridge is provided with retaining knobs for engaging retaining holes in the front end of the pump housing. A cartridge further contains a tab at its rear end for engaging a locking mechanism in the pump housing. The cartridge contains linear fluid conduits which align with the linear peristaltic pumps for pumping fluid from the fluid source pouches within the cartridge. Each pump is individually controlled by a programmable controller within the pump.
    Type: Grant
    Filed: July 8, 1988
    Date of Patent: August 21, 1990
    Assignee: I-Flow Corporation
    Inventors: Eric W. Brown, Charles Kienholz, Steve Busak
  • Patent number: 4938751
    Abstract: Elastomeric bladders having improved resistance to spontaneous rupture when inflated are made by vulcanizing a homogeneous mixture of synthetic polyisoprene having 90% to 98% cis-1,4 linkages, 3 to 10 phr fumed silicon dioxide, and vulcanizing agent while simultaneously forming the mixture into hollow cylindrical bodies. After being formed the bodies are solvent extracted to remove unreacted vulcanizing agent and the degradation products of the vulcanizing agent. Following the solvent extraction about 0.2 to 2 phr of a nontoxic, nonleachable antioxidant are imbibed into the bodies by contacting the bodies with a liquid solution of the antioxidant.
    Type: Grant
    Filed: July 21, 1988
    Date of Patent: July 3, 1990
    Assignee: Alza Corporation
    Inventors: Harold M. Leeper, George V. Guittard
  • Patent number: 4936831
    Abstract: A filter arrangement is inserted in a medication track of an implantable dosage device between a medication reservoir and the medication dosage pump, characterized by the arrangement being fashioned of at least two-ply membrane filter, whose first membrane is composed of non-woven polypropylene fiber-fleece oriented opposite the flow direction of the medication and the second membrane being arranged downstream of the first membrane and being composed of a polypropylene fabric.
    Type: Grant
    Filed: July 10, 1989
    Date of Patent: June 26, 1990
    Assignee: Siemens Aktiengesellschaft
    Inventors: Peter Jaehrling, Eugen Schweikert
  • Patent number: 4936832
    Abstract: A compact disposable delivery system is provided which includes a disposable fluid infusion device for infusing fluid under pressure, a restrictor for controlling the fluid flow, a disposable pressure transducer to receive the pressurized fluid, a catheter connected to the transducer to deliver blood pressure pulses thereto and a recording device electronically connected with the transducer to receive the blood pressure pulses. The fluid infusion device includes a piston which is slidably in the housing under the biasing force of a stretched elastomeric tubing.
    Type: Grant
    Filed: July 10, 1989
    Date of Patent: June 26, 1990
    Inventor: Vincent L. Vaillancourt
  • Patent number: 4934336
    Abstract: An apparatus and method for warming intravenous equipment is disclosed. The apparatus includes at least one warming device comprised of insulated wrap material having at least one removable and reusable heat pack supported along an inner insulated surface of the wrap material. The apparatus releasably encloses intravenous equipment such as I.V. bags and/or I.V. tubing. Two such warming devices can be attached together in series so that one warming device warms the I.V. bag while the other warms a substantial length of I.V. tubing. A flexible insulated strip of material is detachably connected to the wrap material and is used to insulate portions of the I.V. infusion equipment which must be easily accessible and which are neither required nor intended to be heated. The apparatus has particular use for warming intravenous equipment used in routine or emergency pre-hospital situations, especially in cold environments.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: June 19, 1990
    Inventor: Steven J. White
  • Patent number: 4931050
    Abstract: A variable flow constant pressure implantable pump employs an in-line needle restrictor having a variable insertion distance in a capillary. The degree of insertion determines the effective restriction within the capillary. The restrictor may be repositioned following implantation to vary the drug delivery rate by changing the effective restriction in the capillary. Various couplings may be used such that an auxiliary or bolus port delivers infusate directly into the outlet catheter so that medication from the main chamber does not pass through the auxiliary chamber. A combination of double lumen catheters and T-connectors are employed to provide parallel infusion paths.
    Type: Grant
    Filed: April 13, 1988
    Date of Patent: June 5, 1990
    Assignee: Shiley Infusaid Inc.
    Inventor: Samir F. Idriss
  • Patent number: 4921487
    Abstract: A casing holds a syringe that contains a medicine, such as insulin, which may be driven out of the syringe by a plunger into a catheter attached to a human body. The power for the plunger drive mechanism is provided by a spiral spring mounted in the casing. A clockwork movement, regulated by a step electrical motor, controls the speed of the drive mechanism. A microprocessor controls the speed of the step electrical motor which regulates the clockwork movement. All of the components are contained in a casing which has an opening to allow the position of the plunger in the syringe to be seen from outside the casing.
    Type: Grant
    Filed: September 21, 1988
    Date of Patent: May 1, 1990
    Assignee: Compagnie Financiere Saint. Nicolas
    Inventors: Jacques Buffet, Jean-Paul Buffet, Jean Piani, Francois Paravisini
  • Patent number: 4915693
    Abstract: Disclosed is an elastomeric bladder infusion pump which may be used for delivering a pharmaceutically active material to a patient at a substantially constant flow rate. A unitary internal stress member or mandrel is disposed within the bladder, prestressing the bladder in both the axial and radial dimensions.
    Type: Grant
    Filed: September 2, 1988
    Date of Patent: April 10, 1990
    Assignee: Baxter International, Inc.
    Inventor: Stephen R. Hessel
  • Patent number: 4908017
    Abstract: Failsafe apparatus and method are disclosed for controlling fluid flow from syringes. One or more syringes are positioned so that the piston of each syringe is caused to be precisely displaced to thereby safely deliver medicament from the syringe to a patient. To effect movement of each piston, a rack is provided, either as a part of the piston or secured thereto, and longitudinal movement of each rack is effected by rotating an associated pinion gear that is connected with a pulse-driven, stepper motor utilized in a power-efficient electromechanical configuration, with the operation of the stepper motor being accomplished through dual-redundant state machines controlled by a pre-programmed memory unit, and with the apparatus being repeatedly subjected to a plurality of error checks and data integrity verifications to assure continued proper operation.
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: March 13, 1990
    Assignee: Ivion Corporation
    Inventors: David C. Howson, Michael W. Fellinger, John A. Popken, Richard M. Altobellis, Bennett J. Scharf, Walter E. Oshetski
  • Patent number: 4904239
    Abstract: An infusor (10) is disclosed for dispensing a liquid under pressure at a predetermined flow rate. The infusor (10) includes a housing (12) containing an elastomeric bladder (16) for receiving the liquid under pressure. The liquid is delivered from the bladder to a patient through tubing (36). A non-adjustable, preselected flow regulator (38) includes a capillary bore (48). The flow regulator (38) is disposed at the distal end of the tubing (36), such that the tubing may be primed quickly, in a time period virtually unaffected by the flow regulator (38). Distal placement of the flow regulator (38) results in a more constant temperature, and thus a more constant flow rate, of fluid flowing through the flow regulator.
    Type: Grant
    Filed: May 2, 1988
    Date of Patent: February 27, 1990
    Assignee: Baxter International Inc.
    Inventors: David A. Winchell, Derek Walsh
  • Patent number: 4902278
    Abstract: A prime mover module used in a fluid delivery micropump, especially for pharmaceutical purposes, transports an electrochemically active material, such as oxygen, at a steady rate across an ion exchange cell to apply external pressure to a collapsible reservoir and expel fluid therefrom. An air-actuated battery, such as a zinc-air battery, which is located in the module in a fixed closed circuit with the cell and which shares one of its electrodes with the cell, is activated by peeling off an adhesive tape covering air inlet ports to thereby establish a voltage gradient acrosss the cell and control the rate at which fluid is expelled from the reservoir in accordance with the value of a resistor in the cell/battery circuit. The reservoir is filled or refilled by inserting a vented needle into an air bleed port while discharging a fluid-filled syringe inserted into a fluid injection port.
    Type: Grant
    Filed: February 18, 1987
    Date of Patent: February 20, 1990
    Assignee: IVAC Corporation
    Inventors: Henri J. R. Maget, Paul K. Krejci
  • Patent number: 4900305
    Abstract: A pulsed liquid injection device for injection of predetermined dosage volumes of medication at predetermined intervals of time over an extended period is described. A relatively large supply of medication is maintained in a bag under pressure, and metered portions thereof are released at time intervals by an electronically controlled metering device. The metering device includes a simple valve arrangement containing three flexible resilient elements arranged and controlled in such a way as to provide shut off of medication supply in the event of a malfunction, either electrical or mechanical.
    Type: Grant
    Filed: June 27, 1988
    Date of Patent: February 13, 1990
    Assignee: Queen's University at Kingston
    Inventors: Timothy J. N. Smith, Alois J. van Eyken, Charles A. Mulvenna
  • Patent number: 4898582
    Abstract: A portable infusion device assembly, having two side-by-side compartments, the first containing the drug or agent to be infused and an osmotic pump, and the second containing the driving liquid for the pump. The two chambers are separated during storage by a barrier. When the barrier is ruptured, the driving fluid is carried by means of a wick to the osmotic pump. The drug is then forced out of the device by the pressure developed by the osmotic pump. The assembly is characterized by a very flat profile, and is light, comfortable, and inconspicuous in use.
    Type: Grant
    Filed: August 9, 1988
    Date of Patent: February 6, 1990
    Assignee: Pharmetrix Corporation
    Inventor: Rolf A. Faste
  • Patent number: 4898579
    Abstract: An infusion pump for administering fluid from a fluid source to a patient comprises a base member having an electric motor for driving a fluid pump housed within a cassette detachably mountable on the base and connectable to the motor. The cassette houses a reciprocative piston and cylinder assembly which both pumps fluid to the patient while simultaneously drawing fluid from the fluid source so as to maintain a continuous flow rate of fluid to the patient. The cassette also houses deformably closable pairs of tubes connecting each of the pump's two fluid chambers to the cassette inlet and outlet respectively to provide the necessary valving to produce continuous flow in cooperation with the reciprocative piston and cylinder assembly.
    Type: Grant
    Filed: June 3, 1988
    Date of Patent: February 6, 1990
    Assignee: Pump Controller Corporation
    Inventors: Leroy E. Groshong, Judson C. Groshong, R. James Brawn, deceased
  • Patent number: 4886499
    Abstract: The portable appliance is of use for the subcutaneous or intradermal injection of a liquid formulation of an active principle and it comprises in combination: a supply vessel for the formulation; an injection needle adapted to communicate with the vessel; pump means for emptying the vessel through the injection needle; securing means for securing the appliance to an appropriate part of the patient's body; and needle-driving means for shooting the injection needle into the patient's skin.
    Type: Grant
    Filed: December 4, 1987
    Date of Patent: December 12, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Giorgio Cirelli, Hans Steffen, Christian Surber
  • Patent number: 4878896
    Abstract: A cassette identification system for use with a medication infusion system having disposable cassettes which are mounted onto a main pump unit is disclosed which uses an optical sensor module to read the identifying bits from the cassette. The identification indicia contained on the cassette each either pass light through a portion of the cassette, or diffuse the light to prevent it from passing through the cassette. The optical module is mounted on the main pump unit, and includes light sources and sensors for each of the identification indicia on the cassette; the system may use either redundant or non-redundant coding for identifying the cassettes.
    Type: Grant
    Filed: December 1, 1987
    Date of Patent: November 7, 1989
    Assignee: Pacesetter Infusion, Ltd.
    Inventors: Michi E. Garrison, John P. Pelmulder
  • Patent number: 4874359
    Abstract: A modular, power augmented medical infusion apparatus to provide rapid transfusion of relatively large quantities of blood, blood components, colloid, and fluids to patients. All components of the infuser that contact blood are sterlie, disposable, and easily assembled. Disassembled or partially assembled the components are also easily transportable. The major components comprise a pair of filtered cardiotomy reservoirs, an air embolus sensor, a modular double roller pump, a heat exchanger, a bubble trap-filter and disposable fluid conduits. The bubble trap-filter is located in the distal most location of the recirculating loop just upstream of the Y-connector to the patient and the air sensor just downstream of the cardiotomy reservoir in the proximal location of the recirculating loop.
    Type: Grant
    Filed: December 14, 1987
    Date of Patent: October 17, 1989
    Inventors: Frederick R. White, Roy E. Bolles
  • Patent number: 4871351
    Abstract: An implantable medication delivery system comprising an implantable unit with a refillable reservoir, a catheter connected thereto, and a pumping mechanism activated by a microcomputer or microprocessor for pumping medication from the reservoir through the catheter into the body. The implantable medication unit receives information and control commands via a telemetry link from an external controller unit having a microprocessor. The external controller receives feedback in the form of intermittent sampling of blood using enzyme strips and a reflectance meter and/or additional sensor(s) which measure(s) physiological parameter(s) such as heart rate or blood pressure or temperature or skin resistivity. The feedback information is processed by the external unit in accordance with a mathematical model of the patient and the relevant parameters are transmitted to the implanted unit which adjusts its delivery profile according to a prescribed algorithm.
    Type: Grant
    Filed: August 26, 1987
    Date of Patent: October 3, 1989
    Inventor: Vladimir Feingold
  • Patent number: 4867744
    Abstract: A peristaltic pump equipped with a series of rollers eccentrically mounted upon a drive shaft, the pump also includes an elastomeric fluid delivery tube supported to extend in a direction parallel with the axis of the drive shaft. Each roller has a generally cylindrical outer surface equipped with a concentric annular rim that projects radially outwardly beyond the cylindrical surface and is rounded and smoothly tapered when viewed in longitudinal section. The rims of successive rollers are equally spaced and the rim diameter of each eccentric roller is sufficiently large to occlude a section of the tube when that roller is at its perigee with respect to the tube, at which time the adjacent cylindrical surface of the same roller also engages the tube but causes only limited non-occlusive deformation of that tube. The apparatus is particularly useful as a blood pump.
    Type: Grant
    Filed: May 21, 1987
    Date of Patent: September 19, 1989
    Assignee: Baxter International Inc.
    Inventor: Alexander S. Borsanyi
  • Patent number: 4850972
    Abstract: A multiple channel medication infusion system is disclosed which has a plurality of disposable pump cassettes mounted on a single main pump unit, thereby making the system compact and resulting in an economic system. The system has a printer which may be connected to the main pump unit to provide a printed record of system operation. Several modes are accessible to set up and program the system, to monitor actual system performance, and to test the system or display warnings indicating system malfunctions or that new cassettes should be installed.
    Type: Grant
    Filed: January 16, 1987
    Date of Patent: July 25, 1989
    Assignee: Pacesetter Infusion, Ltd.
    Inventors: Joseph H. Schulman, Lanny A. Gorton
  • Patent number: 4846797
    Abstract: A syringe positioning device is disclosed for enhancing control of fluid flow from a syringe. A disposable unit that includes a syringe and rack mounted on a retaining clip is positionable on a drive unit so that, when so positioned, the piston of the syringe is precisely displaced to deliver medicament from the syringe to a patient. A non-disposable unit is also disclosed onto which a syringe and piston can be positioned so that the device thereafter also provides precise medicament delivery. The longitudinal movement of the rack is effected by rotating the pinion gear that is connected with a pulse-driven, power efficient stepper motor, with the operation of the stepper motor being controlled by a pre-programmed memory unit. A hinged rack is also disclosed, as is a one-way ball drive unit.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: July 11, 1989
    Assignee: Intelligent Medicine, Inc.
    Inventors: David C. Howson, Michael W. Fellinger, John A. Popken, Richard M. Altobellis
  • Patent number: 4838857
    Abstract: A medication infusion device comprises a retainer for holding a medication-containing receptacle of the type which is actuatable to expel the contents of medication therefrom. A sensor is included for sensing a characteristic related to the amount of medication within the receptacle. A timing device allows the selection of the period of time over which the contents of the receptacle are to be expelled. A control mechanism, associated with the sensor and the timing device, actuates the receptacle to expel its contents at a controlled rate over the selected period of time.
    Type: Grant
    Filed: February 9, 1987
    Date of Patent: June 13, 1989
    Assignee: Becton, Dickinson and Company
    Inventors: Robert J. Strowe, Floyd V. Edwards, Carl M. Stern
  • Patent number: 4838887
    Abstract: An implantable valve accumulator pump for the delivery of medication is disclosed. The implantable pump comprises a drug reservoir maintained a constant pressure vapor. The medication metering assembly comprises a fixed volume accumulator positioned between a pair of valves. The valves alternately open and close to admit medication from the reservoir into the accumulator and to dispense a precise volume spike to an outlet catheter. In order to minimize dead volume and insure complete discharge, the accumulator employs a titanium diaphragm seated in one position by a recessed stop and in the discharge position by a spacer plate having a groove pattern. The unit is externally programmed.
    Type: Grant
    Filed: December 15, 1987
    Date of Patent: June 13, 1989
    Assignee: Shiley Infusaid Inc.
    Inventor: Samir F. Idriss
  • Patent number: 4838860
    Abstract: An infusion pump for administering fluid from a fluid source to a patient comprises a base member having an electric motor for driving a fluid pump housed within a cassette detachably mountable on the base and connectable to the motor. The cassette houses a reciprocative piston and cylinder assembly which both pumps fluid to the patient while simultaneously drawing fluid from the fluid source so as to maintain a continuous flow rate of fluid to the patient. The cassette also houses deformably closable pairs of tubes connecting each of the pump's two fluid chambers to the cassette inlet and outlet respectively to provide the necessary valving to produce continuous flow in cooperation with the reciprocative piston and cylinder assembly.
    Type: Grant
    Filed: June 26, 1987
    Date of Patent: June 13, 1989
    Assignee: Pump Controller Corporation
    Inventors: Leroy E. Groshong, Judson C. Groshong, R. James Brawn, deceased
  • Patent number: 4820273
    Abstract: A flexible rubber bladder is disposed between a concave surface of a molded plastic base and a mirror image surface of a perforated molded plastic barrier, all enveloped by a molded plastic cover sealed to the base and defining a large volume cavity filled with inert gas under pressure. Injection of medication through a septum in the base fills a reservoir defined by the bladder and concave base surface and compresses the gas as the bladder moves to and against the barrier surface whereby the pressure exerted on the bladder forces medication through a metering outlet in the base and through an attached catheter to the infusion site. The free end of the catheter may be connected to a plastic protective cage for accumulating medication as droplets to dispense medication in bolus quantities.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: April 11, 1989
    Assignee: Eaton Corporation
    Inventor: Robert H. Reinicke
  • Patent number: 4813937
    Abstract: There are depicted two embodiments of an ambulatory disposable infusion delivery system in which fluid (drug) is fed to a substantially transparent receiving and retaining housing which has indicia markings conventionally applied to indicate quantity. The inflow of fluid causes an elastomeric member attached to a piston, which is slideable in a bore in this housing, to be moved, thus stretching this member. This tension provides an energy source (force) to push the fluid out of the bore when the connected tubing line is opened. The housing is provied with a discharge fluid conduit and a restrictor controlling the rate of flow. In both embodiments, the housing has a barrel with a substantially constant bore. The slideable piston in this bore has a resilient outer portion with at least two ribs providing sealing action while having a low coefficient of friction.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: March 21, 1989
    Inventor: Vincent L. Vaillancourt
  • Patent number: 4810243
    Abstract: Device and method are disclosed for effecting application of a therapeutic agent. A removable programmable element is used to control operation of a delivery unit, which unit delivers the therapeutic agent to the patient. The programmable element is programmed, while removed from the delivery unit, by a computer that is operationally independent of the delivery unit to insure the integrity of subsequent delivery of the therapeutic agent to the patient by the delivery unit. The delivery unit requires no microprocessor and can include a plurality of channels for effecting independent delivery of therapeutic agents in each channel under the control of the programmable element. The programmable element is programmed with respect to available protocol informaton, including patient history, needs and tolerances, as well as therapeutic agent parameters, to thereby establish a flow profile that is customized for a particular patient during each moment of each day.
    Type: Grant
    Filed: June 29, 1987
    Date of Patent: March 7, 1989
    Assignee: Intelligent Medicine, Inc.
    Inventor: David C. Howson
  • Patent number: 4808167
    Abstract: A disposable cassette for use with a main infusion pump unit is disclosed which contains both a disposable pump and a battery, thereby requiring the simultaneous replacement of both the pump and the battery. The controller contained in the main pump unit includes a timer which prevents the cassette from being used for longer than a predetermined time, which is substantially less than the life of the battery. An interlock prevents a cassette from being reinstalled following a single use.
    Type: Grant
    Filed: January 16, 1987
    Date of Patent: February 28, 1989
    Assignee: Pacesetter Infusion, Ltd.
    Inventors: Alfred E. Mann, Joseph H. Schulman
  • Patent number: 4808161
    Abstract: A system is provided for controlling flow of a first fluid through a line. Dispensing means isolates a region of the first fluid in the line from effects of pressure in the line outside of the region and repetitively dispenses into and out of the region volume increments of first fluid. Measurement fluid housing means houses measurement fluid in communication with the region such that the dispensing of increments of first fluid into or out of the region causes a change in the measurement fluid pressure. Displacement means displaces a predetermined volume increment of measurement fluid into and out of the measurement fluid housing means, such that displacement of the predetermined volume increment causes a change in the measurement fluid pressure when the region is isolated by the dispensing means. Pressure measurement means measures changes in measurement fluid pressure.
    Type: Grant
    Filed: March 5, 1987
    Date of Patent: February 28, 1989
    Inventor: Dean L. Kamen
  • Patent number: 4798589
    Abstract: The present invention is directed to an improved cassette for use in an intravenous infusion pump. The cassette of the present invention includes a cassette body which is capable of being removably secured within a volumetric pump. The cassette body has a volumetric chamber of predetermined volume which is placed in communication with an inlet and an outlet. The volumetric cassette includes an inlet corridor through which fluid may flow into the cassette. The inlet corridor in turn flows into a central corridor which leads directly to the volumetric chamber. The cassette also includes an outlet corridor which is also in communication with the central corridor and, in turn, the volumetric chamber. Fluid will, therefore, exit the volumetric chamber through the outlet corridor by way of the central corridor. The outlet corridor is then connected to the patient infusion line. The cassette of the present invention also includes a plunger which reciprocates within the interior of the volumetric chamber.
    Type: Grant
    Filed: June 15, 1987
    Date of Patent: January 17, 1989
    Assignee: Fisher Scientific Group Inc.
    Inventor: Gus G. Tseo
  • Patent number: 4781688
    Abstract: A dispensing device for a liquid medicament has a cylindrical support formed on a base which receives an application part fitted into this support and costituting a projection from a cover. An annular reservoir braced against the support is pressed inwardly by a prestressed annular body which can be formed integrally with the reservoir of silicone rubber to drive a liquid medicament through the passage formed in the application part into the body at a constant rate.
    Type: Grant
    Filed: April 6, 1987
    Date of Patent: November 1, 1988
    Assignee: Herwig Thoma
    Inventors: Herwig Thoma, Michael Krotlinger
  • Patent number: 4772263
    Abstract: An implantable infusion pump (20) for infusing drugs or other chemicals or solutions into the body. A flexible spring diaphragm (25) forms an outer back wall portion (26) of a housing (22) of the infusion pump (20). The spring diaphragm (25) applies substantially constant force over a range of displacement and communicating internal body pressure to the drug chamber (30) so as to maintain a substantially uniform pressure difference between the drug chamber (30) and the internal body pressure.
    Type: Grant
    Filed: September 23, 1987
    Date of Patent: September 20, 1988
    Assignee: Regents of the University of Minnesota
    Inventors: Frank D. Dorman, Henry Buchwald
  • Patent number: 4758228
    Abstract: A medical infusion pump includes a housing (10), a pump assembly (30), a bubble sensor assembly (120), a pressure sensor assembly (140) and a flow control assembly (180). The pump assembly includes a ring (26) with teeth (44) and a wheel (46) mounted for eccentric rotation within the ring. The pumping action is developed by the rotation of the wheel which continuously closes a portion of tubing (36) against one or two teeth as it goes through the pumping cycle. The bubble sensor includes a pair of sensor blocks (124) defining a generally V-shaped trough for cradling a portion of the tubing. The pressure sensor assembly detects pressure variations by movement of a diaphragm (168) coupled to a magnet (162) which is operatively coupled to a Hall effect circuit (160). The flow control assembly includes a thumb wheel (196) having a cam groove (197) interacting with a valve stem (199) for controlling the fluid flow through an orifice and associated valve seat (194).
    Type: Grant
    Filed: November 17, 1986
    Date of Patent: July 19, 1988
    Assignee: Centaur Sciences, Inc.
    Inventor: David R. Williams
  • Patent number: 4755168
    Abstract: A medical drainage and irrigation system employs a reversible peristaltic pump to perform both drainage and irrigation. A motor control system independently controls the duty cycle and flow rate during drainage and irrigation using an electronic control to transfer the pumping direction between drainage and irrigation. A loop comprising a flow control valve assembly and external tubes connected thereto may be removed as an assembly for cleaning or discard.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: July 5, 1988
    Inventors: Pat Romanelli, Robert Romanelli
  • Patent number: 4749109
    Abstract: An infusion pump has a removable reservoir including a piston and drive member. The drive member is an internally threaded elongated portion of the piston. A motor rotates a short drive screw, which engages the threads of the drive member to displace the piston in the reservoir. In one embodiment the piston is attached to the drive member by a severable central stem which breaks away to allow engagement with the drive screw. With the stem severed, the piston cannot be retracted, or the reservoir refilled. Other safety features are shown for locking the displaced piston in the reservoir. A digital metering system has a safety circuit to prevent dangerous failure modes of the rotation sensor and motor drive systems.
    Type: Grant
    Filed: September 25, 1986
    Date of Patent: June 7, 1988
    Inventor: Dean L. Kamen
  • Patent number: 4747832
    Abstract: Disclosed is an implantable device for the injection of fluid into a patient's body. The device includes a non-invasive external part which magnetically cooperates with the implanted portion through a magnetic field. The device is entirely mechanical and is capable of delivering both a continuous dose of fluid as well as instantaneous dose of fluid. The mechanism comprises a fluid reservoir, a catheter, an elastic means, a regulating means, a magnetic drive means, a gear transmission means and a flow adjustment means.
    Type: Grant
    Filed: May 16, 1986
    Date of Patent: May 31, 1988
    Inventor: Jacques Buffet
  • Patent number: 4747826
    Abstract: The subject invention relates to a novel system for rapid, venous infusion of a physiologic fluid, such as blood, into a patient, comprising in combination a reservoir for the physiologic fluid having an inlet port for receiving the physiologic fluid and an outlet port for dispensing the physiologic fluid, an infusion pump to propel the physiologic fluid through the system, a heating/cooling unit to control the temperature of the physiologic fluid, a sensor to monitor the pressure of the physiologic fluid, one or move cannula for infusing the physiologic fluid into the venous system of the patient, and flexible conduits connecting the components of the system to the physiologic fluid to and from each of the components of the system.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: May 31, 1988
    Assignee: University of Pittsburgh
    Inventor: John J. Sassano