Sampler Type Patents (Class 141/130)
  • Patent number: 10401372
    Abstract: The present teachings provide apparatuses and methods for automated handling of samples, e.g., biological or chemical samples. The apparatuses and the methods of the present teachings allow automated performance of various sample manipulation steps without manual intervention. In a preferred embodiment, the present teachings provide apparatuses and methods for automated enrichment of templated beads produced by PCR.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: September 3, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Kristopher Barbee, Maximilian Carpino, Ray Wheeling, Nicholas Peter Bajka
  • Patent number: 10365291
    Abstract: The present invention is in the field of automated analyzers and relates to a method for transferring a liquid volume in an analyzer. This involves the tip of a pipetting needle touching a wall of a tilted reaction vessel during the dispensing of liquid.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: July 30, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventor: Thorsten Michels
  • Patent number: 10350604
    Abstract: Covers for microwells, the covers comprising open portions to allow a pipette access to one or more wells and impermeable portions which prevent the liquids from getting into wells shielded by the impermeable portion. The open portions and impermeable portions are preferably arranged and sized to align with alternating rows of wells in a particular microplate. Preferred covers are movably positioned on the microplate and comprise alignment adjusting members for adjusting the alignment of the cover with a microplate. Automated dispensing apparatus for use with microplates and microwell covers comprises a programmable controller, and suitable interfaces which allow the apparatus to be programmed, and which control a dispensing head such that pipettes are moved in the desired manner in order to take advantage of the protective features of the microwell covers. The apparatus also preferably comprises at least one transfer mechanism for moving a cover relative to a microplate at a dispensing station.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: July 16, 2019
    Assignee: Biochemical Diagnostics, Inc.
    Inventor: Allen I. Panetz
  • Patent number: 10324102
    Abstract: Automated apparatus and methods for dispensing fluids into microplates utilizing microwell covers, the covers comprising open portions to allow a pipette access to one or more wells and impermeable portions which prevent the fluids from getting into wells shielded by the impermeable portion. The open portions and impermeable portions are preferably arranged and sized to align with alternating rows of wells in a particular microplate. Preferred covers are movably positioned on the microplate. Automated dispensing apparatus for use with microplates and microwell covers comprises a programmable controller, and suitable interfaces which allow the apparatus to be programmed, and which control a dispensing head such that pipettes are moved in the desired manner in order to take advantage of the protective features of the microwell covers. The apparatus also preferably comprises at least one transfer mechanism for moving a cover relative to a microplate at a dispensing station.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: June 18, 2019
    Assignee: Biochemical Diagnostics, Inc.
    Inventor: Allen I Panetz
  • Patent number: 10138046
    Abstract: A negative pressure storage container includes a container cover, a container body, a rotary device, a gear transmission mechanism and a vacuum pump so arranged that rotating the rotary device drives a driving gear of a transmission gear set of the gear transmission mechanism to rotate an eccentric wheel, causing a link to reciprocate a reciprocating piston of a vacuum pump in creating a negative pressure in the container body. When the negative pressure reaches a certain level, the bottom wall of a plastic inner cover member of the container cover is forced to curve and to carry the driving gear away from the rotary device; at this time, and thus, the rotary device runs idle at this time, preventing overloading the transmission gear set and prolonging the service life of the gear transmission mechanism.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: November 27, 2018
    Assignee: Shin Hung Yih Technology Co., Ltd.
    Inventor: Yi-Hung Ho
  • Patent number: 10139840
    Abstract: A system for fluid dispensing control includes a fluid dispensing control device, a fluid dispenser, and a fluid flow meter, such that an intelligent parameterization of the dispensing system includes process variables, which characterize system behavior. The parameterization is used in convergence schemes for attaining defined fluid dispensing targets. Further, the parameterization is used to attain a consistent volumetric fluid dispensing by utilizing feedback controls. A fluid dispensing device includes a processor, a non-transitory memory, an input/output, a dispensing controller, a flow monitor, a parameterization manager, and a data bus. Also disclosed is a method for fluid dispensing control, including: a parameter sweep, logging system response data, processing response data, calculating system response function, calculating dispensing parameters, assessing intrinsic variation, determining variation band, controlling fluid dispense process response, and normalizing mass/volume fluid flow.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: November 27, 2018
    Inventor: Horatio Quinones
  • Patent number: 10094748
    Abstract: A specimen transfer device having high flexibility is implemented, where a specimen can be transferred between carriers purposed for different kinds of conveyance without decreasing processing speed for the specimen. A plurality of trays that can retain specimen carriers of a transfer destination is provided, and these trays can be freely grouped, and therefore, while a carrier is fed from a tray, a specimen is automatically executed to a carrier in a different tray.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: October 9, 2018
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Masashi Akutsu, Naoto Tsujimura, Kenichi Takahashi, Hiroshi Ohga, Osamu Watabe
  • Patent number: 10036691
    Abstract: A dispensing unit that sucks and discharges a blood specimen via a nozzle. A liquid level-measuring unit that measures the liquid level height. A serum volume-estimating unit that estimates the volume of the serum separated in the blood specimen, on the basis of the total blood volume, said total blood volume corresponding to the volume of the blood specimen and having been derived from the liquid level height, and a hematocrit value. A residual volume-estimating unit that calculates the volume of the serum remaining after suction, on the basis of the serum volume estimated by the serum volume-estimating unit and the volume of the serum that is going to be sucked by the dispensing unit. A controller that controls the suction procedure of the dispensing unit so that the estimated residual volume is not less than the desired volume of the serum to be left in the blood collection tube.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: July 31, 2018
    Assignee: Hitachi, Ltd.
    Inventors: Hitomi Katagi, Haruki Shimokawabe
  • Patent number: 10031051
    Abstract: A device for collecting a sample and for depositing the sample in a sample-receiving port of a measuring apparatus comprises a first connection element (8) with three connections for fluid, and a second connection element (7), and a hollow needle (5) for collecting and depositing the sample. A first feed line (9) for a first washing liquid is connected via a first pump to a first connection for fluid of the first connection element (8). A second feed line (10) for a second washing liquid is connected via a second pump to a second connection for fluid of the first connection element (8). A connection for fluid of the second connection element (7) is connected to the third connection for fluid of the first connection element (8), and the second connection element (7) is connected to a dosing device (1) and to the hollow needle (5). A valve (2) is arranged between the third connection for fluid of the first connection element (8) and the second connection element (7).
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: July 24, 2018
    Assignee: CTC ANALYTICS AG
    Inventors: Werner Doebelin, Thomas Maetzke, Chris C. E. Van Tilburg
  • Patent number: 9910110
    Abstract: A medical imaging device is presented. The medical image device includes a detection unit and a housing unit that surrounds the detection unit. The housing unit has at least one casing shell. The at least one casing shell includes a netlike supporting structure unit and an elastic spring-mass unit. The netlike supporting structure unit is at least partially embedded within the elastic spring-mass unit.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: March 6, 2018
    Assignee: Siemens Healthcare GmbH
    Inventor: Bernd Maciejewski
  • Patent number: 9902027
    Abstract: An instrument changing assembly includes a magazine having one or more probe assembly stations. The assembly further includes at least one probe change tool including a receptacle socket. One or more probe assemblies are retained within the one or more probe assembly stations. The one or more probe assemblies each include a probe receptacle including a probe retention recess and a common socket fitting configured for complementary fitting with a common receptacle socket. The probe change tool is configured to install or extract the respective probes from a mechanical testing instrument according to the complementary fit between the common socket fitting and the common receptacle socket of the probe assemblies. Alternatively, the instrument changing assembly includes an instrument array housing including a plurality of instruments. Each of the one or more instruments (probe and transducer combination) are deployed relative to the instrument array housing with an instrument deployment actuator.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: February 27, 2018
    Assignee: Hysitron, Inc.
    Inventors: Rajiv Dama, Svetlana Zigelman
  • Patent number: 9880076
    Abstract: A compound sampling system has a guiding assembly extending along a sampling path and a shuttle unit having a displacement mechanism engageable to the guiding assembly and configured to displace the shuttle unit onto the guiding assembly. The shuttle unit also includes at least one sampling component configured to monitor a gaseous substance and collect sampling data relative to the compound in the gaseous substance. The sampling system further includes a control system in communication with the shuttle unit. The control system includes a controller communicably coupled to the displacement mechanism and controlling the displacement of the shuttle unit along the sampling path. A method of sampling a compound uses the sampling system.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: January 30, 2018
    Assignee: MORIN ENERTECH INC.
    Inventor: Frédéric Potvin
  • Patent number: 9846172
    Abstract: Automated apparatus and methods for dispensing fluids into microplates utilizing microwell covers, the covers comprising open portions to allow a pipette access to one or more wells and impermeable portions which prevent the fluids from getting into wells shielded by the impermeable portion. The open portions and impermeable portions are preferably arranged and sized to align with alternating rows of wells in a particular microplate. Preferred covers are movably positioned on the microplate. Automated dispensing apparatus for use with microplates and microwell covers comprises a programmable controller, and suitable interfaces which allow the apparatus to be programmed, and which control a dispensing head such that pipettes are moved in the desired manner in order to take advantage of the protective features of the microwell covers. The apparatus also preferably comprises at least one transfer mechanism for moving a cover relative to a microplate at a dispensing station.
    Type: Grant
    Filed: August 9, 2014
    Date of Patent: December 19, 2017
    Assignee: Biochemical Diagnostics, Inc.
    Inventor: Allen I. Panetz
  • Patent number: 9827164
    Abstract: A machine for preparing substances for intravenous application includes: an initial container reception zone, a final container reception zone and a substance transfer circuit which includes a set of substance extraction devices, each of which is connected to a flexible tube connected to a device for introducing a substance into the final container by means of a peristaltic pump. The initial container reception zone and the vector of extraction devices are capable of relative movement along a horizontal axis and/or the final container reception zone and the vector of introduction devices are capable of relative movement along a horizontal axis.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: November 28, 2017
    Assignee: KIRO GRIFOLS, S.L.
    Inventors: Borja Lizari Illarramendi, Naiara Telleria Garay, Ana Belen Barrio Jimenez, Ainara Fol Ruiz De Loizaga
  • Patent number: 9790033
    Abstract: A main drive mechanism provided with a main motor drives a rack on a first main path and a rack on a second main path simultaneously in the forward direction or simultaneously in the reverse direction. The rack is sent along a first auxiliary path by a first auxiliary drive mechanism. Then the rack is further sent in the forward direction along the second main path by the main drive mechanism. Once the rack leaves the first receiving region, the first claw member of the first auxiliary drive mechanism is sent to a retraction position and the rack is driven by the main drive mechanism in the reverse direction. The first claw member is then sent to an engagement position on the first main transportation path, the main drive mechanism is driven for transport in the forward direction, and the rack and the first claw member engage each other.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: October 17, 2017
    Assignee: HITACHI, LTD.
    Inventors: Tomonori Hanaya, Takahiro Yokoyama
  • Patent number: 9746486
    Abstract: The present application provides a sample rack conveying apparatus, a sample rack conveying pipeline, and a sample rack conveying method. The sample rack conveying apparatus includes a track, a detector and dual-channel track switching areas. The detector provided at an outside of the analysis areas to detect whether there is a test tube or not. The dual-channel track switching areas are defined at two ends of the track and positions between every two analysis areas. The track includes an outer track and a parallel inner track. The inner track defines at least two analysis areas. The dual-channel track switching areas include two parallel connecting channels. The connecting channels are moved along a direction perpendicular to the track to transfer the tracks between the inner track and the outer track.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: August 29, 2017
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Chang-Yin Yan, Li-Jian Hu, Jun-Hui Zheng
  • Patent number: 9658144
    Abstract: Systems, methods, and sampling probes for chemically testing a liquid sample are provided. In accordance with one embodiment of the present disclosure, a system generally includes a sample container for containing a liquid, wherein the liquid includes a chemical compound of interest and a reducing agent, and a non-corrosive sampling probe comprising a first channel for delivering a flow of gas to the liquid sample, and a second channel for purging sample fluid from the sample container, wherein at least a portion of the sampling probe is in contact with the liquid.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: May 23, 2017
    Assignee: Brooks Rand Inc
    Inventors: Colin Davies, Paul Danilchik, Steve Gunther
  • Patent number: 9528660
    Abstract: A supercritical fluid extraction system including a housing, motor, linkage assembly, and carriage coupled to the linkage. A piston assembly includes a piston housing with a chamber, back check valve, and piston coupled to the carriage and movable within the piston housing. The piston assembly includes a fluid inlet fluidly communicating with the chamber, and receives, compresses, and expels fluid into an exit fluid line. An intake manifold receives fluid and provides an inlet pathway to the fluid inlet. A single-pass flow path fluidly connects the exit fluid line and a collection chamber, extending through the exit fluid line, a compression chamber, a flow modulator assembly, and the collection chamber. The fluid extracts liquid from solid material within the compression chamber when at a minimum pressure within the compression chamber, passes through the flow modulator assembly and precipitates the extracted liquid into the collection chamber when below the minimum pressure.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: December 27, 2016
    Inventor: Thomas Kotsiopoulos
  • Patent number: 9518897
    Abstract: An exhaust sampling system for an engine is provided. The exhaust sampling system may include a source of exhaust gas, an exhaust collection unit including at least one collection bag that selectively receives the exhaust gas, and a first sample probe in fluid communication with the source of exhaust gas that selectively supplies the at least one collection bag with the exhaust gas at an extraction rate. The exhaust sampling system may also include a controller that permits flow of the exhaust gas from the first sample probe to the at least one collection bag in a first state and prevents flow of the exhaust gas from the first sample probe to the at least one collection bag in a second state. The controller may control the extraction rate of the first sample probe based on a time during a test phase at which the engine is switched to an ON state.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: December 13, 2016
    Assignee: AVL TEST SYSTEMS, INC.
    Inventors: James Patrick Williamson, William Martin Silvis
  • Patent number: 9506941
    Abstract: A rotating holder to invert Petri dishes by 180° and to loosen the bottom from the cover, which has two positions to accommodate Petri dishes. By inverting the rotating holder around a rotation axis, the Petri dishes are reversed and inverted in the two positions. Thus the bottom of the upper Petri dish will be lowered and be engaged by a gripper.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: November 29, 2016
    Assignee: LICONIC AG
    Inventor: Cosmas G. Malin
  • Patent number: 9442047
    Abstract: A segmented sampling apparatus is designed to extract a sample from a source and deliver the sample to a collector for storage or analysis. The sample is extracted from the source at a sample withdrawal or extraction rate but is delivered to the collector at a faster rate. Air is injected into or drawn into the apparatus which allows for an expedited sample delivery rate.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: September 13, 2016
    Assignee: Flownamics Analytical Instruments, Inc.
    Inventor: Michael J. Biksacky
  • Patent number: 9415404
    Abstract: A method and apparatus for dispensing a fluid. In one illustrative embodiment, an apparatus may comprise a housing comprising a chamber, a dispensing device, and a nozzle system. The housing may be configured to receive the fluid. The housing may be configured to increase a tendency of the fluid to flow within the chamber. The dispensing device may be configured to move the fluid in the chamber towards an exit of the chamber such that the fluid is dispensed through the exit of the chamber. The nozzle system may be configured to control an exit pressure of the fluid that is dispensed through the nozzle system.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: August 16, 2016
    Assignee: THE BOEING COMPANY
    Inventors: Chin H. Toh, Trent Rob Logan
  • Patent number: 9352865
    Abstract: A device for filling a flexible container and a method thereof are disclosed. The device may include a pressurizing chamber and an evacuation chamber. A first displacement piston is sealingly and slideably arranged within the pressurizing chamber to define an inner volume within the pressurizing chamber that is fluidly connected to a pressurizing conduit. A second displacement piston is sealingly and slideably arranged within the evacuation chamber to define an inner volume within the evacuation chamber that is fluidly connected to an evacuation conduit. A reservoir adapter is fluidly connected to the pressurizing conduit and connects to a liquid reservoir. A container adapter is fluidly connected to the evacuation conduit and connects with a flexible container. A transfer conduit is fluidly connected to the reservoir adapter and the container adapter. A valve fluidly connects the container adapter to the evacuation conduit or the transfer conduit.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: May 31, 2016
    Assignee: Roche Diagnostics International AG
    Inventors: Florian Kuehni, Christoph Huwiler, Martin Wyss
  • Patent number: 9296542
    Abstract: A vacuum storage container includes a container housing, a drawer mounted in the container housing and movable between a closed position and an open position, a rotary knob pivotally mounted in a door cover of the drawer, clockwork coupled to the rotary knob, a drive gear affixed to the rotary knob, a transmission gear set rotatable by the drive gear, an eccentric wheel rotatable by the transmission gear set, a pumping pump mounted in the drawer and coupled to the eccentric wheel for creating a vacuum in the container housing, an ejection mechanism adapted for ejecting the drawer out of the container housing, and an operating member control mechanism adapted for locking the drawer to the container housing and operable to unlock the drawer for enabling the drawer to be ejected out of the container housing by the ejection mechanism.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: March 29, 2016
    Assignee: SHIN HUNG YIH TECHNOLOGY CO. LTD.
    Inventor: Yi-Hung Ho
  • Patent number: 9022079
    Abstract: A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: May 5, 2015
    Assignee: MedInstill Development LLC
    Inventors: Daniel Py, Norbert Assion, Nathaniel Houle, Debashis Sahoo, M. Jeffrey Willey, Eric E. Hartman, John Guthy
  • Patent number: 8726944
    Abstract: A method in a fraction collector for accurate positioning of a dispensing device with respect to wells of a micro plate in which prior to the dispensing a sensing device is moved over the micro plate the sensing device being able to detect the number of walls between the wells in the rows and columns of the micro plate.
    Type: Grant
    Filed: April 22, 2009
    Date of Patent: May 20, 2014
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Johan L. Carlsson, Hakan Frojdh, Pia Liljedahl, Lars Rosengren, Johan Svensson, S. Fredrik Svensson, Bengt Asberg
  • Patent number: 8561376
    Abstract: The disclosure relates to a device for dispensing a prescribed product in a Petri dish, the device comprising pistons, a transfer member with lid-bearing openings and a dish bottom, and a dispensor. According to the disclosure, the transfer member is a shuttle capable of translation relative to the base according to a direct reciprocating movement of the bearing openings between either of first and second stop positions, the dispensor being arranged so as to dispense the product above the inner opening and under the upper opening at the bottom of the dish when the openings are in a position selected from the first and second stop positions.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: October 22, 2013
    Assignee: AES Chemunex
    Inventor: Nicolas Brelivet
  • Patent number: 8479784
    Abstract: A filling line for filling a number of containers. The filing line may include a continuous conveyor, one or more micro-ingredient dosers positioned about the continuous conveyor, and one or more macro-ingredient stations positioned along the continuous conveyor.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: July 9, 2013
    Assignee: The Coca-Cola Company
    Inventors: James E. Goldman, James LeSage, Donald E. Gruben, Kevin L. Reid, Jonathan Kirschner, Nilang Patel
  • Patent number: 8448674
    Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a resealable stopper or portion and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the resealable portion and chamber for sterilizing the container. The previously sterilized containers are then transported through another sterilizing chamber, such as an e-beam chamber, to sterilize the penetrable surface. A filling member is moved into engagement with the resealable portion to pierce the sterilized penetrable surface of the resealable portion and inject the substance through the filling member and into the chamber of the container. Energy is then transmitted onto the stopper to hermetically re-seal the penetration in the resealable portion.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: May 28, 2013
    Assignee: Medical Instill Technologies, Inc.
    Inventor: Daniel Py
  • Patent number: 8408256
    Abstract: Apparatus for filling containers having stoppers that are penetrable for filling the containers with a substance, and thermally resealable for thermally sealing the resulting hole. A container support supports at least one such container in a substantially fixed position during filling and resealing. A manifold drivingly mounted over the container support comprises (1) a cartridge including a filling needle for penetrating the resealable stopper and introducing a substance therethrough into the container, a mount for mounting the cartridge on the manifold, and a removable cover releasably coupled to the mount for covering the filling needle during transportation, installation and/or removal of the cartridge from the manifold. The manifold includes a thermal source for heating a penetrated region of the stopper and, sealing the hole.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: April 2, 2013
    Assignee: Medical Instill Technologies, Inc.
    Inventor: Daniel Py
  • Patent number: 8386070
    Abstract: In a preferred implementation, an automated pharmacy admixture system (APAS) prepares intermediary IV bags as drug sources for creating highly diluted patient doses in syringes. During the compounding process the APAS may align needles with a vial seal opening so as to ensure repeated entry through the same vial puncture site via precise control of needle position, needle bevel orientation, and needle entry speed. These techniques can in certain implementations substantially improve bung pressure sealing and reduced particulate generation. The APAS optionally creates drug order queues for incoming drug orders wherein the orders can be sorted by priority, drug type or patient location. A phantom queue can be combined with the incoming drug order queues to include frequently used medicaments to minimize operator loading of the APAS.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: February 26, 2013
    Assignee: Intelligent Hospital Systems, Ltd
    Inventors: Walter W. Eliuk, Ronald H. Rob, Lance R. Mlodzinski, Alex H. Reinhardt, Thom Doherty, Dustin Deck
  • Patent number: 8273009
    Abstract: A device for aspirating sample media into a pipette for use in a micro-manipulation procedure includes a ring member having an opening sized for receiving a digit of an operator, and an aspirating bulb engaged with the ring member. The aspirating bulb has an open end sized for receiving an end of the pipette, and includes a compressible chamber capable of creating a suction force suitable for aspirating the sample media into the pipette. The aspirating bulb is oriented along the ring member such that the chamber is compressible by a digit on the same hand of the operator as the digit receivable in the ring member.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: September 25, 2012
    Assignee: Cook Medical Technologies LLC
    Inventors: Dustin John Arabia, Chad E. Unger
  • Patent number: 8245740
    Abstract: A device for positioning a component thereof along x- and y-axes of the device is provided. The device includes first and second motors, a carriage containing the component to be positioned, a lead screw to position the carriage along a first axis of the device, and a keyed shaft to position component to be positioned along a second axis of the device. The first motor drives the lead screw and the second motor drives the flatted shaft. In some embodiments described herein, the flatted shaft turns a first pulley, which is connected to a second pulley by a belt. The component to be positioned is attached to the belt and moves along a second axis of the device as the belt moves.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: August 21, 2012
    Assignee: Alfa Wassermann, Inc.
    Inventors: Marcus J. Horn, Blaine Marsh
  • Patent number: 8163238
    Abstract: An automated micro-well plate handling device for removing a micro-well plate from within a vertically stacked plurality of micro-well plates and transferring the removable micro-well plate to a receiving area. A vertical storage device for storing the vertically stacked plurality of micro-well plates creates a vertical clearance space between the vertically stacked micro-well plates. A shovel slides into the vertical clearance space underneath the micro-well plate that is being removed. The shovel then removes the micro-well plate from the vertical storage device and places the micro-well plate at a transfer station. A gripper then grabs the micro-well plate from the transfer station and transfers the micro-well plate to a receiving area. In a preferred embodiment, the automated micro-well plate handling device is controlled via a computer network.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: April 24, 2012
    Assignee: Let 's Go Robotics, Inc.
    Inventors: Brian L. Ganz, Nicholas P. Pratte, Anthony L. Moore, Chinapong Songchan
  • Patent number: 7905257
    Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a heat resealable stopper and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the stopper and chamber for sterilizing the container. The previously sterilized containers are then transported through another sterilizing chamber, such as an e-beam chamber, to sterilize the penetrable surface. A needle is moved into engagement with the stopper to pierce the sterilized penetrable surface of the stopper and inject the substance through the needle and into the chamber of the container. Laser energy is then transmitted onto the penetrated surface of the stopper to fuse the stopper material and hermetically re-seal the stopper.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: March 15, 2011
    Inventor: Daniel Py
  • Patent number: 7886579
    Abstract: A portable sampler for use in an explosion-endangered area, having a housing, in which at least the following components are arranged: a pump unit having a first drive unit, a sensor for determining the amount of sample supplied from the pump unit, a control unit, which controls the taking of a desired amount of sample and the filling thereof into at least one container, and at least one power supply unit, which provides the power for driving the first drive unit, the sensor and the control unit, The following components: the control unit, the power supply unit, the first drive unit and the sensor, are modularly constructed, and each such module is embodied such that it satisfies a specified ignition protection type.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: February 15, 2011
    Assignee: Endress + Hauser Wetzer GmbH + Co. KG
    Inventors: Peter Zinth, Wolfgang Steidle, Tobias Stuckl
  • Publication number: 20100229999
    Abstract: A method, system and apparatus for an automated sample introduction system, utilizing a demountable direct injection high efficiency nebulizer (d-DIHEN) is provided which incorporates an inductively coupled plasma optical emission spectrometer (ICP-OES) for the measurement of the phosphorus content in acid-digested nucleotides and deoxyribonucleic acid (DNA). The solution uptake rate and volume are reduced from 170 ?L min?1 to 30 ?L min?1 and 10 mL to 2.4 mL, respectively, thereby reducing the required DNA sample mass for solutions containing 3 ?g?1 P from 300 ?g to 72 ?g DNA, in comparison to previous analyses in our lab using a glass, concentric nebulizer with cyclonic spray chamber arrangement. The use of direct injection also improves P (I) 213.617 nm sensitivity by a factor of 4 on average.
    Type: Application
    Filed: March 10, 2010
    Publication date: September 16, 2010
    Inventors: Ryan G. Brennan, Savelas A. Rabb
  • Patent number: 7783383
    Abstract: In a preferred embodiment, an automated Pharmacy Admixture System (APAS) may include a manipulator system to transport medical containers such as bags, vials, or syringes in a compounding chamber regulated to a pressure below atmospheric pressure. In a preferred implementation, the manipulator system is configured to grasp and convey syringes, IV bags, and vials of varying shapes and sizes from a storage system in an adjacent chamber regulated at a pressure above atmospheric pressure. Various embodiments may include a controller adapted to actuate the manipulator system to bring a fill port of an IV bag, vial, or syringe into register with a filling port at a fluid transfer station in the chamber. A preferred implementation includes a sanitization system that can substantially sanitize a bung on a fill port of a vial or IV bag in preparation for transport to the fluid transfer station.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: August 24, 2010
    Assignee: Intelligent Hospital Systems Ltd.
    Inventors: Walter W. Eliuk, Ronald H. Rob, Lance R. Mlodzinski, Alex H. Reinhardt, Thom Doherty
  • Publication number: 20090277286
    Abstract: A rack for preparing samples for analysis is provided. The rack includes a frame, a sliding assembly, a first and a second receptacle mounted in the frame underneath the sliding assembly; and means for selectively connecting each receptacle with a vacuum source. The sliding assembly is mounted for sliding in the frame and is provided with a plate having a plurality of columns for receiving samples through an upper opening of the columns. The sliding assembly is movable between a first position above the first receptacle and a second position above the second receptacle. The sliding assembly is provided with engagement means for a needle, wherein the engagement means are located outside the columns.
    Type: Application
    Filed: July 21, 2009
    Publication date: November 12, 2009
    Inventor: Michel Kubacki
  • Patent number: 7610943
    Abstract: Systems and methods are provided for dispensing portions of viscous material, such as the viscous materials used to form crystals of membrane proteins or soluble proteins. A liquid under pressure is used to divide the viscous materials into portions. The divided viscous material portions can optionally be deposited into are receptacle.
    Type: Grant
    Filed: June 8, 2005
    Date of Patent: November 3, 2009
    Assignee: Emerald Biosystems, Inc.
    Inventors: Peter Nollert, Alexandrina Muntianu, Robert C. Haushalter, Dean Allyn Hopkins, Jr.
  • Patent number: 7608456
    Abstract: In a microplate processing apparatus that removes lid (11) of microplate (10) conveyed by microplate conveying mechanism (3), performs a dispensing process by dispensing head (8), and attaches lid (11) after the dispensing process is completed, lid (11) removed by lid removing mechanism (6) at second position (P2), is conveyed to fourth position (P4) located downstream, in advance of microplate (10) with this lid (11) having been attached, by microplate conveying mechanism (3), to be retained by lid attaching mechanism (9), and then is attached to microplate (10) having been conveyed to fourth position (P4), after the dispensing process is completed.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: October 27, 2009
    Assignee: Panasonic Corporation
    Inventors: Akira Higuchi, Eiji Watanabe
  • Patent number: 7556066
    Abstract: A sterile filling machine and related method are provided for sterile filling a container with a substance. The container includes a heat resealable stopper and a chamber for receiving the substance therein. The sealed, empty containers are subjected to radiation capable of penetrating through the stopper and chamber for sterilizing the container. The previously sterilized containers are then transported through another sterilizing chamber, such as an e-beam chamber, to sterilize the penetrable surface. A needle is moved into engagement with the stopper to pierce the sterilized penetrable surface of the stopper and inject the substance through the needle and into the chamber of the container. Laser energy is then transmitted onto the penetrated surface of the stopper to fuse the stopper material and hermetically re-seal the stopper.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: July 7, 2009
    Assignee: Medical Instill Technologies, Inc.
    Inventor: Daniel Py
  • Publication number: 20090090433
    Abstract: The invention is directed to a dispensing unit suitable to precise! dispense material in powder and/or granular form. The dispensing device comprises a gate valve opening sealingly closed by a blend. A control unit, which is interconnected to a scaling device, controls the opening of the gate valve opening by the position of the blend. The precise amount of the material is adjusted in relation to the signal of the scaling device.
    Type: Application
    Filed: April 13, 2006
    Publication date: April 9, 2009
    Applicant: Symyx Technologies Europe SA
    Inventors: Loic Pluvinage, Antonio Valella, Gian-Luigi Berini, Pascal Courtin
  • Patent number: 7503356
    Abstract: There is provided a low-cost liquid supply apparatus using a system in which a liquid nozzle is moved, the apparatus being configured so that the installation area of the apparatus is small, a liquid vessel can be installed or removed easily without being hindered by equipment for moving the liquid nozzle, and further the number of parts is small. The liquid nozzle is attached to an arm capable of being turned reversibly around a turning shaft, and the movement of the liquid nozzle is controlled by the turning angle of the arm for either one axis of the X-axis and the Y-axis and is controlled by changing the length of the arm from the turning shaft for the other axis.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: March 17, 2009
    Assignee: Uniflows Co., Ltd.
    Inventor: Hideyuki Morikawa
  • Patent number: 7485465
    Abstract: In a microplate processing apparatus that removes lid (11) of microplate (10) conveyed by microplate conveying mechanism (3) to perform a dispensing process by dispensing head (8), and that attaches lid (11) after the dispensing process is completed, lid (11) removed by lid removing mechanism (6) at first position (P1) is conveyed to third position (P3) located downstream, by microplate conveying mechanism (3), to be held by lid attaching mechanism (9), and then lid (11) is attached to microplate (10) having been conveyed to third position (P3), after the dispensing process is completed, while microplate (10) with this lid (11) having been attached is being lifted to processing position (P4) above microplate conveying mechanism (3), by microplate stage (12).
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: February 3, 2009
    Assignee: Panasonic Corporation
    Inventors: Akira Higuchi, Eiji Watanabe
  • Patent number: 7452510
    Abstract: A multi-well microfiltration apparatus and method are provided and feature a manual touch-off system for transferring pendent drops hanging from discharge-conduits of a discharge-conduit array to respective receiving wells or receiving holes of a corresponding receiving array, with minimum or no cross-contamination between the discharge conduits, or the receiving wells or receiving holes. The manual touch-off is achieved by manually shifting a carriage that supports one of the arrays, into a position whereat pendent drops of fluid hanging from the distal ends of the discharge conduits contact the inner sidewalls of the corresponding receiving wells or receiving holes of the receiving array.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: November 18, 2008
    Assignee: Applied Biosystems Inc.
    Inventors: Todd A. Weinfield, Gary Lim, Donald R. Sandell, Kevin S. Bodner, Mark Borodkin, Mark Oldham, Jon Hoshizaki
  • Patent number: 7365343
    Abstract: Apparatus for introducing a medicament into containers, especially vials, in which the containers are passed through an enclosure and exposed therein to a sterilising electron beam. The containers are then conveyed to a filling station situated outside the enclosure at which a wall part of the container is punctured with a filling needle and medicament introduced into the container via the needle then withdrawing the needle. Preferred apparatus also includes means for heat sealing the puncture site. A corresponding process is disclosed.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: April 29, 2008
    Assignee: GlaxoSmithKline Biologicals s.a.
    Inventors: Jacques Thilly, Christian Vandecasserie
  • Patent number: 7318461
    Abstract: The container carrier serves to hold containers for fluid samples. For the transport of the sample containers, the container carrier, which is directly but detachably connected with a cover part during the dispensation of fluid samples into the sample containers, is separated from the cover part, with the sample containers remaining in the container carrier in transport. A transport cap is provided for closing the container carrier in transport, particularly in a fluid-tight manner.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: January 15, 2008
    Assignee: Endress + Hauser Wetzer GmbH + Co. KG
    Inventor: Robert Zeller
  • Patent number: 7308913
    Abstract: A liquid filling apparatus includes a discharge head having a cavity for storing liquid, a nozzle communicated with the cavity, and a discharge device for discharging liquid stored in the cavity through the nozzle. In addition, the apparatus includes a liquid supply section which supplies the liquid to the nozzle of the discharge head by contacting the liquid with the nozzle, and a suction device connected to a cavity side of the discharge head, which draws liquid supplied from the liquid supply section to inside the cavity, by suction from the nozzle via the cavity.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: December 18, 2007
    Assignee: Seiko Epson Corporation
    Inventors: Nobuko Watanabe, Takeo Kawase, Hirotsuna Miura
  • Patent number: 7270158
    Abstract: An apparatus is provided for needle filling and thermally resealing containers having stoppers that are needle penetrable for filling the containers with a substance, and are thermally resealable for thermally sealing a needle hole in the stopper upon withdrawal of a needle therefrom. A container support of the apparatus supports at least one container having a resealable stopper in a substantially fixed position during needle filling and thermally resealing a needle hole in the stopper upon withdrawal of a needle therefrom.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: September 18, 2007
    Assignee: Medical Instill Technologies, Inc.
    Inventor: Daniel Py