Abstract: A disposable skin-worn device for the transdermal delivery at least one dose of charged therapeutic substances, including granisetron, by iontophoresis, the device comprising a donor reservoir containing an amount of a therapeutic substance to be delivered transdermally by iontophoresis, a counter reservoir, a source of electric power connected in a circuit between the donor reservoir and the counter reservoir and a control system for controlling current flow in the circuit to enable at least one dose of the therapeutic substance to be delivered transdermally by iontophoresis and wherein the control system includes a control element selected from the group consisting of a sensor activated by an external signal and a switch.

Abstract: A tote having both a caddy and a removable mini caddy is disclosed. The removable mini caddy attaches to the caddy with a series of guide walls and guide rails that allow the removable mini caddy to be cooperatively received by the caddy. The handle of the removable mini caddy nests with the handle of the caddy while they are attached, providing the user with a single handled tote that is easy to transport and use while still having the convenience of an extra tote where objects can be temporarily removed and then replaced without the need for transferring the objects from one tote to another. The removable mini caddy may be easily removed and then replaced within the caddy while remaining securely in place during use and transport.