Abstract: Analyte sensing devices suitable for measuring pH or other analytes are provided in a variety of form factors, including a hand-held device.

Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.

Abstract: A fluid resistance section outside a fuel cell can regulate the reactant flow against the pressure changes in the reaction zones of the electrodes, reducing the fluctuations in reactant flows to the fuel cell electrodes due to dynamic fluctuations in fluid pressure at the fuel cell electrode because of the release of gaseous products. The outside fluidic resistor can have resistance much higher than the resistance of the flow through the electrodes, thus effectively determining the amount of the reactant flow to the electrodes, independent of the electrode areas.

Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.

Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.

Abstract: A system for obtaining a pH measurement comprises a disposable probe and a reusable reader. The disposable probe includes an indicating electrode and a reference electrode. The reader operably engages the disposable probe and provides pH information of a sample. The system is configured to be self-calibrating. The system is constructed and arranged to provide pH information based on the potentiometric measurement of the sample solution based on signals received from the at least one indicating electrode and the at least one reference electrode.

Abstract: This invention prevents leakage of an internal liquid and breakage of a reference electrode resulting from volume expansion of the internal liquid due to the congelation of the internal liquid, and comprises a vessel that forms a sealed space, an internal liquid that is contained in the vessel, an internal electrode that is immersed in the internal liquid, an ion conduction part that is arranged on a wall of the vessel and that electrically connects the internal liquid and a measurement sample, and a volume expansion absorption mechanism 6 at least a part of which is immersed in the internal liquid and that absorbs volume expansion of the internal liquid due to congelation of the internal liquid.

Abstract: Systems, devices, and/or methods for use in passive wireless transmission of one or more parameters such as, e.g., pH, temperature, etc. are described. The systems, devices, and/or methods may use a passive sensor located proximate a material and an interrogator that may be used to interrogate the passive sensor and to receive a signal from the passive sensor representative of the one or more parameters.

Abstract: An electrode for use in a electrochemical sensor comprises carbon modified with a chemically sensitive redox-active compound, excluding an electrode based on carbon having derivatized thereron two redox-active species wherein at least one of said species is selected from anthraquinone, phenanthrenequinone and N,N?-diphenyl-p-phenylenediamine (DPPD). The invention further provides a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material; and a counter electrode, wherein the ratio of the surface area of the working electrode to the surface area of the counter electrode is from 1:10 to 10:1. Also provided is a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material, and a counter electrode, wherein the area of the working electrode is from 500 ?m2 to 0.1 m2. The uses of these electrodes and sensors are also described.

Abstract: A cathodic material for use in an electrochemical sensor comprising: a carbonaceous material and an oxygen reduction catalyst associated with the carbonaceous material; and wherein the cathodic material does not materially exhibit catalytic activity for the oxidation of carbon monoxide. Associated electrochemical sensors may include an anode and cathode that are disposed upon the same or opposite sides of an ion exchange membrane and/or exposed to the same or different gaseous environments.

Abstract: Matrix materials such polymers derivatives to contain a redox active material can be used to form electrodes and probes suitable for use in pH meters and other analyte sensing devices.

Abstract: A sensor device includes first and second electrodes, a coating film and a functional element. The first electrode includes a first metallic material in which either a first passivation film forms on a surface thereof or the first passivation film present on the surface thereof is lost, in association with changes in the pH of a measurement site. The second electrode includes a second metallic material different from the first metallic material, and is spaced apart from the first electrode. The coating film includes a third metallic material different from the first and second metallic materials. The coating film covers at least the first or second electrode. The functional element is configured to measure a difference in electric potential between the first and second electrodes that changes depending on presence or absence of each of the first passivation film and the coating film in association with the changes in pH.

Abstract: Disclosed is a pH and conductivity sensor including a carrier comprising a plurality of conductive tracks and an exposed conductive area defining a reference electrode connected to a first track of said plurality of conductive tracks, a sensing device mounted on the carrier and connected to at least a second track of said plurality of conductive tracks, the sensing device including an exposed surface that is sensitive to H+ concentrations, and a plurality of electrodes adjacent to the exposed surface, an encapsulation covering the carrier, said encapsulation including a first cavity exposing a surface of the sensing device, and a second cavity exposing the exposed conductive area.

Abstract: A low-slope pH electrode (100) is provided according to an embodiment of the invention. The low-slope pH electrode (100) includes an electrode body (102), a pH-sensitive glass (122) fused into the electrode body (102), with the pH-sensitive glass (122) including a predetermined area, and a mask (124) formed over a predetermined portion of the predetermined area of the pH-sensitive glass (122) in order to form a low-slope pH characteristic. At least a portion of an ion exchange performed by the pH-sensitive glass (122) is blocked by the mask (124).

Abstract: An ionic probe is provided according to the invention. The ionic probe includes an active electrode configured to generate a measurement signal for an external test fluid, a first reference electrode configured to generate a first reference signal, and an at least second reference electrode configured to generate at least a second reference signal. The measurement signal is compared to the first reference signal and the at least second reference signal in order to determine an ionic measurement of the external test fluid.

Abstract: A cathodic material for use in an electrochemical sensor comprising: a carbonaceous material and an oxygen reduction catalyst associated with the carbonaceous material; and wherein the cathodic material does not materially exhibit catalytic activity for the oxidation of carbon monoxide. Associated electrochemical sensors may include an anode and cathode that are disposed upon the same or opposite sides of an ion exchange membrane and/or exposed to the same or different gaseous environments.

Abstract: Carbon nanostructures may be protected and functionalized using a layer-by-layer method whereby functional groups on the carbon nanostructure surface may be further derivatized to incorporate additional functional moieties. Exemplary moieties include redox mediator molecules, crown ethers, catalysts, boric acids, carbohydrates, oligonucleotides, DNA or RNA aptamers, peptide aptamers, proteins such as enzymes and antibodies, quantum dots and nanoparticles, cells, cell organelles, or other cellular components. The density of functional groups or functional moieties on carbon nanostructure surfaces may also be controlled as well as the degree of surface hydrophilicity of the nanostructure.

Abstract: Carbon nanostructures may be protected and functionalized using a layer-by-layer method whereby functional groups on the carbon nanostructure surface may be further derivatized to incorporate additional functional moieties. Carbon nanostructures functionalized using such a layer-by-layer method may be used to disperse, sort, separate and purify carbon nanostructures and may be used as sensing elements such as voltammetric, amperometric, and potentiometric pH sensors or as biometric sensing elements and electrodes and intracorporeal sensors and electrodes.

Abstract: A system for measuring a solution pH includes a potentiostat with a working electrode made of an electro-conductive solid polymer transducer, an input to receive the potential to be applied between the working electrode and a reference electrode, and an output to transmit a signal representative of the current flowing between a counter electrode and the working electrode, the three electrodes being immerged into the solution. The system further includes a digital processor connected to a digital to analog converter for generating the potential to be applied between the working and the reference electrodes; and to an analog to digital converter for receiving a digital value representative of the current. The digital processor is adapted to modify the potential to maintain the current inside a predetermined range such that the potential is representative of the solution pH when the current is inside the predetermined range.

Abstract: A system for measuring pH includes a substrate and a sensor medium on the substrate. The sensor medium includes at least one oxidized carbon nanostructure and optionally at least one composition immobilized on the at least one oxidized carbon nanostructure. The at least one composition has at least one property that depends on pH. The system further includes at least one measurement system to measure a property of the sensor medium.

Abstract: An electrochemical sensor device including a sensor chip having an integrated electrochemical sensor element; and a substrate having a first surface on which the sensor chip is mounted, the substrate comprising a reference electrode structure for the integrated electrochemical sensor element, the reference electrode structure connected to the sensor chip via an electrical connection on the first surface of the substrate.

Abstract: The present invention provides a PH value detection device and a method of detecting a PH value of a solution. The PH value detection device may comprise: a first electrode and a second electrode, wherein the first electrode and the second electrode are to be inserted into the solution; a power source for applying a bipolar rectangular potential pulse signal to the first electrode and the second electrode; a current detection means connected between the first electrode and the second electrode for detecting a current I flowing through the first electrode and the second electrode; and a calculating unit for calculating the PH value of the solution, based on the detected current I. By means of the above design of the present invention, the use of the fragile glass electrode and the reference electrode, e.g.

Abstract: A low maintenance reference electrode has a liquid junction body with a multiplicity of micron-sized capillary channels extending through the body for transporting electrolyte to a test solution. A viscosity-increasing agent thickens the electrolyte to limit its flow to a rate on the order of microliters/day so that a few milliliters of electrolyte suffice to provide an extended electrode life.

Abstract: Disclosed is a pH sensor comprising a carrier (10) comprising a plurality of conductive tracks and an exposed conductive area (40) defining a reference electrode connected to one of said conductive tracks; a sensing device (30) mounted on the carrier and connected at least one other of said conductive tracks; an encapsulation (20) covering the carrier, said encapsulation comprising a first cavity (22) exposing a surface (32) of the sensing device and a second cavity (24) exposing the exposed conductive area, said second cavity comprising a reference electrode material (42) and an ion reservoir material (44) sharing at least one ion type with said reference electrode material, the reference electrode material being sandwiched between the exposed conductive area and the ion reservoir material. A method of manufacturing such a pH sensor is also disclosed.

Abstract: An aspect includes a low slope electrode device, including: at least one electrode; at least one container at least partially enclosing the at least one electrode and having at least one ion sensitive region; an external buffer container having at least one separating element that separates said at least one ion sensitive region into: a first ion sensitive area separating an internal buffer solution bathing the at least one electrode and an external sample solution; and a second ion sensitive area separating the internal buffer solution bathing the at least one electrode and an external buffer solution; wherein the at least one separating element, the first ion sensitive area, and the second ion sensitive area establish a charge flow circuit. Other aspects are described and claimed.

Abstract: The present disclosure relates to a sensor for detecting hydrogen ions in an aqueous solution comprising a support, a reference electrode, a working electrode and a counter electrode supported by said support, the reference electrode being made of a material comprising silver and silver chloride, the counter electrode being made of a conductive material. The working electrode comprises a substrate and a layer made of an inherently electrically conductive polymer of the polythiophene or polyaniline (PANI) or polypyrrole class.

Abstract: Systems and methods are provided for a deep sea pH sensor. In one embodiment, a method for manufacturing a pH sensor comprises forming a sensor electrode in a working surface of a die wherein the sensor electrode is able to sense the pH of a liquid and forming at least one isolation groove around the sensor electrode on the working surface of the die, wherein the die has a wide street around the sensor electrode and the at least one isolation groove. The method further comprises mounting the die onto a base and securing a seal on the working surface in the wide street, wherein the seal surrounds the isolation groove, the seal sealing the liquid within the portion of the working surface of the die containing the sensor electrode and the isolation groove, when the pH sensor is subjected to high pressure.

Abstract: One or more charge pumps may be used to amplify the output voltage from a chemically-sensitive pixel that comprises one or more transistors. A charge pump may include a number of track stage switches, a number of boost phase switches and a number of capacitors. The capacitors are in parallel during the track phase and in series during the boost phase, and the total capacitance is divided during the boost phase while the total charge remains fixed. Consequently, the output voltage is pushed up.

Abstract: Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.

Abstract: An electrochemical sensor and a method for using an electrochemical sensor are described where the electrochemical sensor comprises a working electrode having thereon one or more redox species that are sensitive to an analyte to be measured and a polymer coating that provides for interaction between the redox species and the analyte.

Abstract: An electrochemical half cell for application in an electrochemical sensor, wherein a fill electrolyte of the half cell is in contact with an external medium via a liquid junction, characterized in that the liquid junction is controllable as regards its permeability and/or its flow.

Abstract: A potentiometric sensor includes an elongate non-glass, non-metal housing having opposite first and second longitudinal ends and a length extending between the first and second longitudinal ends. The housing defines a lumen extending along the length of the housing. A measuring half-cell assembly is received in the lumen of the housing and secured to the housing. The measuring half-cell assembly includes a glass body having opposite first and second longitudinal ends and a length extending between the first and second ends of the glass body. The second longitudinal end of the glass body is adjacent the second longitudinal end of the housing and a longitudinal extent of the glass body is less than the length of the housing.

Abstract: An electrode for use in a electrochemical sensor comprises carbon modified with a chemically sensitive redox-active compound, excluding an electrode based on carbon having derivatised thereron two redox-active species wherein at least one of said species is selected from anthraquinone, phenanthrenequinone and N,N?-diphenyl-p-phenylenediamine (DPPD). The invention further provides a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material; and a counter electrode, wherein the ratio of the surface area of the working electrode to the surface area of the counter electrode is from 1:10 to 10:1. Also provided is a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material, and a counter electrode, wherein the area of the working electrode is from 500 ?m2 to 0.1 m2. The uses of these electrodes and sensors are also described.

Abstract: The present invention provides an apparatus and method for measuring carbon (any one or all of TC, TOC, or TIC) in a sample matrix. In an embodiment, a method for measuring carbon in a sample composition is provided. The method comprises providing an apparatus comprising a reaction chamber and a diamond coated electrode, wherein the diamond coated electrode is doped with boron. The apparatus further comprises a detector. In addition, the method comprises contacting the sample composition with the electrode. The method further comprises applying an alternating current to the electrode at a sufficient voltage to produce carbon dioxide. Moreover, the method comprises measuring the amount of carbon dioxide produced.

Abstract: A method for operating an ion-sensitive sensor with a measurement circuit which includes an ion-sensitive electrolyte-insulator-semiconductor structure (EIS); wherein the measurement circuit is embodied to issue an output signal which is dependent on ion concentration, especially a pH value, of a measured liquid; and wherein the method comprises the steps of: introducing the ion-sensitive electrolyte-insulator-semiconductor structure into a measured liquid; accelerating charging processes in the region of an insulator layer of the ion-sensitive electrolyte-insulator-semiconductor structure by operating the sensor over a predetermined time span at least a first working point; and dynamically adapting the working point to set a second working point, and registering and processing the output signal of the measurement circuit at the second working point.

Abstract: Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.

Abstract: A cathodic material for use in an electrochemical sensor comprising: a carbonaceous material and an oxygen reduction catalyst associated with the carbonaceous material; and wherein the cathodic material does not materially exhibit catalytic activity for the oxidation of carbon monoxide. Associated electrochemical sensors may include an anode and cathode that are disposed upon the same or opposite sides of an ion exchange membrane and/or exposed to the same or different gaseous environments.

Abstract: The invention relates to a device and a method for performing maintenance on an apparatus. The device has a flow duct with a wall section in which at least one apparatus which projects into the flow duct and which is to be reworked after a certain operating time is arranged. A vessel which is open towards the wall section is arranged to as to be movable relative to the wall section in such a way that in an open position it is arranged at a distance from the apparatus, and in a second position forms, together with the wall section, a sealed volume which is separated from the rest of the flow duct and in which the maintenance of the apparatus is performed.

Abstract: Systems and methods are provided for a deep sea pH sensor. In one embodiment, a method for manufacturing a pH sensor comprises forming a sensor electrode in a working surface of a die wherein the sensor electrode is able to sense the pH of a liquid and forming at least one isolation groove around the sensor electrode on the working surface of the die, wherein the die has a wide street around the sensor electrode and the at least one isolation groove. The method further comprises mounting the die onto a base and securing a seal on the working surface in the wide street, wherein the seal surrounds the isolation groove, the seal sealing the liquid within the portion of the working surface of the die containing the sensor electrode and the isolation groove, when the pH sensor is subjected to high pressure.

Abstract: Provided is an ion sensor with which the concentration of ions in a solution can be determined without any reference electrode. The ion sensor is equipped with: a first electrode plate; a second electrode plate which has been disposed opposite the first electrode plate and has one or multiple openings; an ion-sensitive film continuously formed so that the film is interposed between the first electrode plate and the second electrode plate, blocks up one side of each opening of the second electrode plate, and extends from the end of that side of the opening to the outer surface of the second electrode plate through the inner wall surface of the opening; and a sensor support which supports the second electrode plate so that when the ion concentration of a test solution to be examined is determined, the ion-sensitive film comes into contact with the test solution only in the portions thereof that have been formed in each opening and on the outer surface of the second electrode plate.

Abstract: A multiple-electrode ion meter (100) is provided. The multiple-electrode ion meter (100) includes meter electronics (102) configured to receive a plurality of ionic concentration voltage measurements and generate an ionic concentration measurement from the plurality of ionic concentration voltage measurements and three or more individual electrode units (108) in communication with the meter electronics (102). The three or more electrode units (108) generate the plurality of ionic concentration voltage measurements to the meter electronics (102).

Abstract: An apparatus and method for electrochemical fluid analysis comprises a chamber (1202) having a depth dimension for accommodating a volume of a fluid under test, first and second electrodes (A1) disposed within the chamber and extending along the depth dimension in spaced relation with each other, and a soluble solid, such as an annealed polymer, e.g. EUDRAGIT occupying a lateral gap between the first and second electrodes. The rate of dissolution as monitored by electrochemical impedance spectroscopy (EIS) of the soluble solid within the fluid depends on the chemical concentration of a corresponding analyte present in solution in the fluid. In one embodiment a silicon-based integrated circuit device defining an upper margin includes an array of electrodes disposed along said upper margin to permit direct exposure of the electrode array to the fluid under test. The device is constructed using CMOS technology.

Abstract: Improvements in references electrodes, halogen sensors, pH sensors, TDS sensors, combinations thereof, and related methods.

Abstract: An electrode for use in a electrochemical sensor comprises carbon modified with a chemically sensitive redox-active compound, excluding an electrode based on carbon having derivatised thereron two redox-active species wherein at least one of said species is selected from anthraquinone, phenanthrenequinone and N,N?-diphenyl-p-phenylenediamine (DPPD). The invention further provides a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material; and a counter electrode, wherein the ratio of the surface area of the working electrode to the surface area of the counter electrode is from 1:10 to 10:1. Also provided is a pH sensor comprising: a working electrode comprising carbon modified with a chemically sensitive redox active material, and a counter electrode, wherein the area of the working electrode is from 500 ?m2 to 0.1 m2. The uses of these electrodes and sensors are also described.

Abstract: Glass pH electrode with integrated optical sensor, characterized in that said electrode can be sterilized without substantial alteration of its optical characteristics, in particular in respect to gamma ray irradiation sterilization.

Abstract: The present invention provides a pH sensing apparatus that includes a flexible polymer substrate, one or more amorphous iridium oxide film sensor electrodes disposed on the flexible polymer substrate, and a reference electrode corresponding to each amorphous iridium oxide film sensor electrode. Each reference electrode is disposed on the flexible polymer substrate in close proximity to the corresponding amorphous iridium oxide film sensor electrode. The amorphous iridium oxide film sensor electrodes provide a potential in reference to the reference electrodes that varies according to a pH of a substance contacting the amorphous iridium oxide film sensor electrodes and the reference electrodes.

Abstract: An ionic probe is provided according to the invention. The ionic probe includes an active electrode configured to generate a measurement signal for an external test fluid, a first reference electrode configured to generate a first reference signal, and an at least second reference electrode configured to generate at least a second reference signal. The measurement signal is compared to the first reference signal and the at least second reference signal in order to determine an ionic measurement of the external test fluid.

Abstract: A voltammetric pH sensor, especially for characterising wellbore fluids, comprises a plurality of electrodes with a redox active organic compound attached to an electrode and having at least one functional group convertible electrochemically between reduced and oxidized forms with transfer of at least one proton between the compound and surrounding aqueous phase, wherein the compound has at least one substituent group which promotes hydrogen bonding at a said functional group and thereby increases the reaction rate of proton transfer. The substituent group may form an internal hydrogen bond with a redox-convertible group or may enhance polarity to promote electrostatic interaction with water molecules and reduce activation energy.

Abstract: Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration.

Abstract: A microlectrode comprising a diamond layer formed from electrically non-conducting diamond and containing one or more pins or projections of electrically conducting diamond extending at least partially through the layer of non-conducting diamond presenting areas of electrically conducting diamond.