Abstract: A water treatment device includes, between at least two flat sheet-shaped grounded electrodes vertically disposed so as to be parallel to each other, a sheet-shaped high-voltage electrode having two edges opposing the respective grounded electrodes. The sheet-shaped high-voltage electrode is supported by a plurality of support members, and thus deformation of the high-voltage electrode in an up/down direction and a horizontal direction is suppressed, and the distance between each edge of the high-voltage electrode and the corresponding grounded electrode, i.e., an electric discharge gap length, can be kept even. Accordingly, uniform electric discharge can be maintained between the high-voltage electrode and the grounded electrode, whereby highly efficient water treatment can be realized.

Abstract: A microfluidic apparatus for separating a droplet of an emulsion in a microfluidic environment is described. The microfluidic apparatus includes a flow cell comprising a first microfluidic channel configured for flowing a first fluid through the flow cell and a second microfluidic channel configured for flowing a stream of a second fluid through the flow cell. The microfluidic apparatus further comprises a first electrode positioned at the first microfluidic channel and a second electrode positioned at the second microfluidic channel on an opposite side of the interface with respect to the first electrode. The first electrode, the second electrode, and the first and second microfluidic channels are configured to generate a non-uniform electric field gradient in the microfluidic apparatus.

Abstract: The present invention relates to a ballast water treatment system and a ballast water treatment method.

Abstract: A device for sensing a property of a fluid comprising a first substrate having formed thereon a sensor configured in use to come into contact with a fluid in order to sense a property of the fluid, and a wireless transmitter for transmitting data over a wireless data link and a second substrate having formed thereon a wireless receiver for receiving data transmitted over said wireless link by said wireless transmitter. The first substrate is fixed to or within said second substrate. Additionally or alternatively, the device comprises a first substrate defining one or more microfluidic structures for receiving a fluid to be sensed and a second substrate comprising or having attached thereto a multiplicity of fluid sensors, the number of sensors being greater than the number of microfluidic structures.

Abstract: The invention achieves a lower noise of a sense signal of a FET-type hydrogen sensor. For solving the above problem, one aspect of a sensor system of the invention includes a reference device and a sensor device configured using FETs on a substrate, and further, well potentials of the reference device and the sensor device are electrically isolated from each other.

Abstract: In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of at least one agent that generates a ligatable terminal 5? phosphate group by removing an adenylate group from a terminal 5? phosphate of a nucleic acid. In some embodiments, an aprataxin enzyme can catalyze removal of an adenylate group from a terminal 5? phosphate of a nucleic acid. In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of an aprataxin enzyme under conditions suitable for ligating nucleic acid ends.

Abstract: A sensor device includes a sensor array and a flow cell in fluid communication with the sensor array. Bias circuitry apply bias arrangements to the sensor array to produce sensor data. Peripheral circuitry coupled to the bias circuitry produces streams of data from the sensor array, the peripheral circuitry having an active mode and an idle mode. Logic to switch the peripheral circuitry between the active mode and the idle mode to control power consumption is provided. A temperature sensor may be included, and the logic can operate with feedback to switch between the active mode and the idle mode to maintain the temperature within an operating range.

Abstract: An array of micro-chambers (220) with individual ion sensitive field effect transistors (ISFETs) (300) disposed therein for monitoring single cell activity in the microarray to determine the presence or absence of microorganisms in a sample (390). In addition to the presence or absence of a single cell, certain further embodiments contemplate monitoring cell behavior. Cell behavior includes the entire range of cell activity as well as cell response to changes in environmental conditions of changes in response due to the addition of sample constituents.

Abstract: The present disclosure provides a liquid treatment device, a liquid treatment method, and a plasma treatment liquid each capable of efficiently generating plasma and treating a liquid in a short time period. A liquid treatment device according to the present disclosure includes a first electrode, a second electrode disposed in a liquid to be treated, an insulator disposed around the first electrode with a space between the first electrode and the insulator, the insulator has an opening portion in a position in contact with the liquid to be treated, a power supply that applies voltage between the first electrode and the second electrode, and a supply device supplying a liquid to the space before the power source applies the voltage.

Abstract: There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using DNA sequencing to identify personalized biomarkers in patients with autoimmune disease and other conditions. Identified biomarkers can be used to determine the disease state for a subject with an autoimmune disease or other condition.

Abstract: A device, apparatus and method for trapping metal ions and detecting metal ion contamination in a solution provide a semiconductor device formed on a semiconductor substrate and including an N-well formed over a P-type substrate and at least a contact portion of the N-well in electrical contact with the solution. When the semiconductor device is optically illuminated, a P/N junction is formed as a result of photovoltaic phenomena. Metal ions from the solution migrate to the contact area due to the voltage created at the P/N junction. The semiconductor device includes a conductive structure with conductive features separated by a gap and therefore in an initially electrically open state. When the ions migrate to the contact area, they precipitate, at least partially bridging the gap and creating conductance through the conductive structure. The conductance may be measured to determine the amount of metal ion contamination.

Abstract: A centralized supply system for electrolyzed oxidizing water comprises a water softener (1), several parallel electrolyzed oxidizing water generators (2) connected, liquid storage tanks (3, 4) and delivery pumps (5, 6). A central controller (10) implements independent control over the several parallel electrolyzed oxidizing water generators (2). Liquid level sensors (9) are mounted in the liquid storage tanks (3, 4) and are connected with the central controller (10) via data collection cables (12). With the detection, determination and calculation for the liquid level signal in the liquid storage tanks (3, 4) using the central controller (10), the volume magnitude and the rate of change of the volume for the liquid in the liquid storage tanks (3, 4) can be exactly obtained in time. The electrolyzed oxidizing water generators (2) are effectively controlled based on above data. An intelligent control method for the system is also provided.

Abstract: A device for displacing a small volume of liquid under the effect of an electric control, including a first substrate with a hydrophobic surface provided with a first electrical conductor, a second electrical conductor positioned facing the first conductor, and a third conductor, forming with the second conductor, a mechanism for analyzing or heating a volume of liquid.

Abstract: This invention relates to microfluidic systems and more particularly to methods and apparatus for accessing the contents of micro droplets (114) in an emulsion stream. A method of accessing the contents of a droplet (114) of an emulsion in a microfluidic system, the method comprising: flowing the emulsion alongside a continuous, non-emulsive stream of second fluid (118) to provide an interface (120) between said emulsion and said stream of second fluid (118); and in embodiments applying one or both of an electric (112a, 112b) and magnetic field across said interface (120) to alter a trajectory of a said droplet (114) of said emulsion to cause said droplet to coalesce with said stream of second fluid (118); and accessing said contents of said droplet (114) in said second stream (118).

Abstract: Described herein are systems, methods, and apparatuses for aggregating microorganism in an aqueous suspension. In particular, are systems, methods, and apparatuses that apply an electrical field to an aqueous suspension comprising microorganisms as the aqueous suspension follows a flow path to cause aggregation of the microorganisms. The electrical field may comprise different types of pulses. In some embodiments, the flow path for the aqueous suspension may vary.

Abstract: In an electrolytic apparatus for removing contaminants from water, a set (110) of spaced apart conductive electrodes (40) in a reaction chamber (54, 112, 114), is arranged in oppositely charged groups of first and second interleaved electrodes with flow paths between them. Non-conductive turbulence inducers (158, 168) on the faces of electrodes (40) are applied to water in the flow paths. One variety is modular elements (158) with stepped increases in width to present a narrow leading edge in the direction of flow. Another variety is a continuous set of wave guides (168) bordering the flow path. Electrodes (40) are selectively powered in patterns creating turbulence, with effective patterns including a first and last electrode powering pattern and a mini-cell electrode powering pattern.

Abstract: A water treatment system provides treated water to a point of use by removing at least a portion of any hardness-causing species contained in water from a water source, such as municipal water, well water, brackish water and water containing foulants. The water treatment system typically receives water from the water source or a point of entry and purifies the water containing at least some undesirable species before delivering the treated water to a point of use. The water treatment system has a pressurized reservoir system in line with an electrochemical device such as an electrodeionization device. The water treatment system can have a controller for adjusting or regulating at least one operating parameter of the treatment system or a component of the water treatment system. The electrochemical device can be operated at a low current and low flow rate to minimize water splitting or polarization, which minimizes scale formation.

Abstract: The plasma-generating apparatus includes a treatment vessel 509 containing to-be-treated water 510, a first electrode 504 and a second electrode 502 within the treatment vessel, a bubble-generating part which generate a bubble 506 such that a surface where conductor of the first electrode 504 is exposed to the to-be-treated water is positioned within the bubble 506, a gas-supplying apparatus 505 which supplies gas to the bubble-generating part, a pulsed power supply 501 connected to the first and the second electrodes 502 and 504, a control apparatus 520 which controls one or both of the gas-supplying apparatus and the power supply such that the voltage is applied between the first and the second electrodes 502 and 504 when at least surface where the conductor of the first electrode 504 is exposed is positioned within the bubble.

Abstract: A system and method for quantifying opaque inhomogeneities within a fluid sample. The system uses an optical lens system to focus a light beam onto a stage where the sample is introduced. The light beam is directed onto the sample in a pattern such that the intensity of transmitted light is measured as a function of path length. A photo detector measures the transmitted light through the sample. Fluctuations in transmitted light intensity are then correlated with detection of opaque inclusions in the sample. The system also includes an automated program which utilizes these optical concentration measurements to determine the fouling potential of visbroken tars, and regulates the introduction of chemical inhibitors into a visbreaker unit to improve the yield of light streams and/or economic value of product.

Abstract: Methods for sampling a liquid flow are provided. The method includes supplying a continuous liquid flow from a continuous flow fluid input source to a surface along a first flow path. The method additionally includes sampling the continuous liquid flow by performing an electric field-based technique to split off a sample droplet from a portion of the liquid flow, whereby the sample droplet is distinct from the liquid flow and controllable independently of the liquid flow, wherein the electric field-based technique is performed by providing a set of electrodes on the surface and selectively biasing the set of electrodes, whereby the sample droplet is formed on one of the set of electrodes.

Abstract: Water treatment, reconditioning, and reclamation systems and methods are described. The systems utilize two treatment vectors. The first treatment vector is created by flowing electrical current through a first conductive rod. The second treatment vector is created by delivering a magnetic pulse by way of a second conductive rod. Water to be treated is exposed to the two vectors simultaneously, which is accomplished by creating relative motion between the conductive rods and the water, either by moving the conductive rods or by moving the water. The electric current of the first treatment vector and the voltage and frequency of the magnetic pulse of the second treatment vector may be reduced as the treatment process proceeds. During treatment, total dissolved solids (TDS) rise and congeal at the top of the water. The congealed TDS are removed from the water. An additional filtering process may be applied.

Abstract: An exemplary, highly integrated, SPM-based system for measuring the conductivity and/or force of substance under programmable engaging/stretching processes is described. A sample bias is applied across two electrodes. A substance to be measured is sandwiched between them. A first electrode is first brought relative to a second electrode (engaging) in programmable pathways that can be described as stretching distance versus time curves. The process of engaging the electrodes continues until a certain current reached, a certain force reached and whichever case happens first. The electrodes are then separated (stretching) in programmable pathways that can be described as stretching distance versus time curves. A periodic modulation can be applied to the engaging/stretching process to realize different stretch pathways. The sample bias across the electrodes is kept constant or swept in a programmable shape over time, described as a voltage-versus time curve.

Abstract: This invention relates to microfluidic systems and more particularly to methods and apparatus for accessing the contents of micro droplets (114) in an emulsion stream. A method of accessing the contents of a droplet (114) of an emulsion in a microfluidic system, the method comprising: flowing the emulsion alongside a continuous, non-emulsive stream of second fluid (118) to provide an interface (120) between said emulsion and said stream of second fluid (118); and in embodiments applying one or both of an electric (112a, 112b) and magnetic field across said interface (120) to alter a trajectory of a said droplet (114) of said emulsion to cause said droplet to coalesce with said stream of second fluid (118); and accessing said contents of said droplet (114) in said second stream (118).

Abstract: A method for solid material detection in a medium includes receiving an exhaust gas downstream with respect to a workpiece from which a photoresist material is removed. An electromagnetic circuit is configured to include the exhaust gas, the exhaust gas is excited with electromagnetic energy and an impedance value of the electromagnetic circuit is determined, wherein the impedance value corresponds to an amount of solid material within the exhaust gas.

Abstract: An embodiment of the invention relates to a device comprising (1) an array of electromagnetic elements comprising coils, metal cores, and metal core heads, and (2) a controller that is adapted to control a current for one or more coils individually, to vary the current for said one or more coils individually, to reverse the current for one or more coils individually, and to generate a specific magnetic flux distribution and gradient across two or more coils; wherein the metal core head is at one end of the coil and the metal core head has a geometry to create a desired magnetic flux, intensity and gradient, in a region of interest between two adjacent coils; further wherein the device is functionally coupled to a fluidic device to concentrate and transport magnetic particles in a fluid without fluidic movement of the fluid.

Abstract: An oil cleaning device is provided with: at least a first electrostatic cleaner comprising at least one voltage source, and at least two metal plates connected to said voltage source; and at least one free radical sensor for determining the content and/or type of free radicals in the oil.

Abstract: A portable apparatus for treating polluted water by electrocoagulation. The apparatus comprising at least two electrodes (1,2). The apparatus also includes a housing (4), electrically isolated from the at least two electrodes (1,2), to which the at least two electrodes (1,2) are fixed spaced apart from one another. When the at least two second electrodes (1,2) are at least partly submerged in the polluted water and provided with an electrical potential, one of the at least two electrodes (2) is sacrificial so as to provide ions to the polluted water.

Abstract: A method of separating gaseous components, heavier liquid components and lighter liquid components of a stream including the steps of conducting the stream between spaced apart electrodes in a treatment vessel, supplying from a voltage source an AC voltage of at least one base frequency F1 to at least one of the electrodes to establish an electric field within the vessel through which the stream passes, modulating the frequency F1 of the AC voltage at a modulation frequency F2, and withdrawing separated gaseous components from an upper portion of the vessel, heavier stream components from a lower portion of the vessel, and lighter liquid components from an intermediate portion of said vessel.

Abstract: Methods for performing microfluidic sampling are provided. The method includes providing a substrate including an arrangement of first, second and third electrodes, wherein the second electrode is interposed between the first and third electrodes. The method additionally includes causing a fluid input to continuously flow to the first electrode and biasing the first, second and third electrodes to a first voltage to cause a portion of the fluid input to spread across the second and third electrodes. The method further includes biasing the second electrode to a second voltage different from the first voltage to form a droplet on the third electrode, the droplet being separate from the fluid input.

Abstract: A portable apparatus for treating polluted water by electrocoagulation. The apparatus comprising at least two electrodes (1,2). The apparatus also includes a housing (4), electrically isolated from the at least two electrodes (1,2), to which the at least two electrodes (1,2) are fixed spaced apart from one another. When the at least two second electrodes (1,2) are at least partly submerged in the polluted water and provided with an electrical potential, one of the at least two electrodes (2) is sacrificial so as to provide ions to the polluted water.

Abstract: Water treatment, reconditioning, and reclamation systems and methods are described. The systems utilize two treatment vectors. The first treatment vector is created by flowing electrical current through a first conductive rod. The second treatment vector is created by delivering a magnetic pulse by way of a second conductive rod. Water to be treated is exposed to the two vectors simultaneously, which is accomplished by creating relative motion between the conductive rods and the water, either by moving the conductive rods or by moving the water. The electric current of the first treatment vector and the voltage and frequency of the magnetic pulse of the second treatment vector may be reduced as the treatment process proceeds. During treatment, total dissolved solids (TDS) rise and congeal at the top of the water. The congealed TDS are removed from the water. An additional filtering process may be applied.

Abstract: Performance of equipment, such as a desalter, in a refinery is monitored in real-time and on-line to minimize fouling of downstream equipment. Using an instrument to measure particles and droplets in-process allows monitoring of the various operations to optimize performance. Such measurement can also be used during crude oil blending to detect asphaltene precipitates that can cause fouling and can be used for monitoring other fouling streams.

Abstract: The present invention discloses a method for measuring the zeta potential at the cylinder's outer surface. In the measuring cell, the cylinder is held coaxially inside a reference tube and a given solution is forced to flow through the annular flow channel between the cylinder and the reference tube. The streaming potential induced by the flow forced with a hydraulic pressure drop is measured to determine the zeta potential, ?m, of the cylinder's outer surface by using the following Equation, E _ ? ? ? P == - D ? ? ? k ? ( ? m + ? ref 2 ) ? F where D is the permittivity, ?ref is the zeta potential of the reference tube, ? is the viscosity of the solution, k is the electric conductivity of the solution, and F is a correction factor for the electrokinetic model. Moreover, this invention also discloses a system for measuring the zeta potential of the cylinder's outer surface.

Abstract: A fluidic device, the fluidic device comprising a planar fluidic conduit for conducting a fluid, wherein the fluidic conduit has a plurality of fluidic disturbance features located along at least a section of the fluidic conduit for disturbing a laminar flow of the fluid along the section.

Abstract: An apparatus and method for electrochemically modifying the retention of a species on a chromatography material is disclosed. The apparatus comprises a housing having an effluent flow channel adapted to permit fluid flow therethrough. The effluent flow channel comprises chromatography material. The apparatus further comprises first and second electrodes positioned such that at least a portion of the chromatography material is disposed between the first and second electrodes, and fluid flow through the apparatus is between, and in contact with, the first and second electrodes.

Abstract: The invention describes a family of sensors for assaying macro-molecules and/or biological cells in solution. Each sensor has the form of a well (a hollow cylinder having a floor but no lid) or a trench whose walls comprise a plurality of GMR or TMR devices. Suitably shaped magnets located below each well's floor pull labeled particles into the well/trench and up against the inner wall where a field gradient orients them for optimum detection. Any unattached labels that happen to also be in the well/trench are removed through suitably sized holes in the floor.

Abstract: Disclosed are an apparatus and a method for detecting particles and microorganisms using a magnetic field. The apparatus comprises a magnetic sensor that is provided at an outside of a passage pipe and measures a magnetic field induced by fluid moving in the passage pipe; an electrode that is provided in the passage pipe so as to apply electric current having a predetermined frequency to the fluid moving in the passage pipe to measure impedance; and a signal processing unit that uses an intensity of the magnetic field measured by the magnetic sensor and the impedance measured by the electrode to determine concentrations of particles and microorganisms included in the fluid.

Abstract: Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.

Abstract: Disclosed herein is an electrostatic fluid filtration system suitable for removing sub micron insoluble contaminants known to cause varnish from fluids such as dielectric fluids. The electrostatic fluid filtration system is configured to remove both water and other contaminants from a target fluid (e.g. a dielectric fluid) and comprises a cabinet, a computer control unit, and one or more substantially cylindrical filtration units, including at least one of a water filtration unit and an electrostatic contaminant filtration unit. In the contaminant filtration unit, the target fluid flows radially through the filtration media that is positioned between the electrode plates in a generally horizontal flow pattern. This forces the target fluid to traverse multiple energy fields in a serpentine fashion and in a single pass through the contaminant filtration unit. After flowing through each layer of the filtration media, the target fluid is discharged from the electrostatic contaminant filtration unit.

Abstract: A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the blood sample.

Abstract: Particle collection, transport, and detection systems are disclosed. The systems are uniquely adapted for collecting or concentrating particles from a flowing medium and then transporting the collected particles to a desired location or for subsequent analysis. Electrostatic traveling wave grids can be used in conjunction with sample concentrators.

Abstract: A method for quantitative evaluation of emulsion stability using Critical Electric Field (CEF) determinations over a range of conditions, such as a range of temperatures, demulsifier compositions, or demulsifier concentrations. The method includes determining the CEF for a series of emulsions that differ substantially only in their internal phase volume ratio. A plot of CEF values as a function of the inverse of the internal phase volume ratio is characterized by a linear slope. Using the slope, a theoretical CEF value can be determined by extrapolating to where the inverse of the internal phase volume ratio is about one. The slope for a given emulsion series is associated with the relative energy barrier to flocculation and the theoretical critical electric field for a given emulsion series is associated with the relative energy barrier to coalescence. Comparative studies are performed using this method.

Abstract: A method of augmenting the separation of immiscible heavier and lighter components of an emulsion including the steps of conducting the emulsion into a treatment vessel, providing an AC voltage source, employing from the source an AC voltage of at least one selected frequency F1 to establish at least one electric filed within the vessel through which the emulsion passes, and cyclically modulating the AC voltage with a method of modulation selected from: (a) amplitude modulation; (b) frequency modulation; and (c) combined amplitude and frequency modulation.

Abstract: A fluid treatment system for reducing odor, bacteria, and biological oxygen demand from a fluid having at least one tube, a control box, and a pump. The at least one tube has a plurality of conductors in electrical communication with the control box. The control box controls the level of electrical communication to the plurality of conductors and the flow rate of the pump. The principle use is for biomass material derived from animals, however other fluids will benefit from this invention. For example, fluids derived from plants and humans will benefit from this application.

Abstract: Particle collection, transport, and detection systems are disclosed. The systems are uniquely adapted for collecting or concentrating particles from a flowing medium and then transporting the collected particles to a desired location or for subsequent analysis. Electrostatic traveling wave grids can be used in conjunction with sample concentrators.

Abstract: A method of augmenting the separation of immiscible heavier and lighter components of an emulsion including the steps of passing the emulsion into a treatment vessel, establishing at least one dual frequency electric field within the vessel and selectably varying the electric field at a frequency F1 modulated in intensity at a frequency F2 where F1 is greater than F2.

Abstract: A device and method for generating drops. The drops are generated by applying an electrical potential to a set of feeding tips which have immiscible or poorly miscible liquids running through them.

Abstract: System for treating fluids, especially water, in a pipe to resist scale deposits from building up in the pipe, includes a field generating coil (10) mounted exteriorly of the pipe, an electronic circuit (14) for energizing the coil to develop an alternating electromagnetic field in the fluid, a sensor (18) for sensing a parameter related to the functioning of the system and for generating a parameter dependant signal, a feed back circuit for feeding back the parameter dependent signal to the electronic circuit to control the circuit, wherein the sensor comprises a field measuring coil (16) mounted exteriorly of the pipe near the field generating coil, the feed back circuit comprises the electronics which together with the measuring coil acts as a field strength meter.

Abstract: This invention relates to methods for reducing the presence of a compound in an ionically conductive material, e.g., for use in iontophoretic devices, wherein the presence of the compound interferes with detecting a selected analyte. Removal of the compound can typically take place either during or after the manufacture of the ionically conductive material or an assembly comprising this material. Also disclosed are methods for generating selectively permeable barriers on the reactive faces of electrodes. Further, this invention relates to hydrogels comprising one or more biocides, as well as assemblies containing such hydrogels.

Abstract: An apparatus that is useful for evaluating and optimizing electrochemical processes and for electrochemically characterizing materials includes a base or substrate carrying a plurality of electrodes, at least one housing member that is secured to the base or substrate to define an electrochemical cell volume for holding an electrolyte in contact with the plurality of electrodes carried on the base, and a counter electrode disposed in the cell volume. The apparatus may be used for rapidly evaluating various parameters that influence electrochemical deposition processes, electrolytic processes and electrochemical cell performance.