Abstract: A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.

Abstract: An envelope is configured to hold, support, and protect an article such as a blood bag during transportation under cryogenic temperatures. The envelope includes a single piece component (e.g., a monolithic component), including multiple panels that are configured to fold to form an enclosure that surrounds the article such as the blood bag for support and protection of the article such as the blood bag.

Abstract: A pedicle screw assembly including a pedicle screw, a tulip head, a set screw, and a washer; a packaging assembly for a pedicle screw; a pedicle screw screwdriver assembly; and a set packaging assembly are disclosed.

Abstract: An apparatus includes a flexible container and a port. The container includes a first layer coupled to a second layer to define a storage volume within which a tissue specimen can be contained. The first layer has a first stiffness and the second layer has a second stiffness. An edge of the first layer is spaced apart from an edge of the second layer to define an opening into the storage volume. The edges of the first and second layer form a peelable seal that hermetically seals the storage volume such that the first layer can be peeled away from the second layer to expose the storage volume. The port is coupled to the flexible container and allows fluid communication between the storage volume and an external volume.

Abstract: A primary packaging container for pharmaceuticals is provided. The container includes a hollow body, an opening, and a closure. The hollow body has an opening and is made of a cycloolefin polymer or a cycloolefin copolymer. The closure has a puncture region. The closure closes the opening with the puncturing region at the opening. The puncturing region is configured to allow introduction of a cannula into the hollow body and resealing the hollow body upon withdraw of the cannula. The closure has an elastomer that is connected to the hollow body so as to be not separable in a non-destructive manner.

Abstract: A dental implant with an implant extension which are formed along a longitudinal axis: the dental implant has an apical end, a coronal end and a section for receiving; securing an abutment; the implant extension is formed in one piece with the implant; extends away from an end face of the apical end along the longitudinal axis, the implant extension having a first section along the longitudinal axis with an annular constriction which is directly connected to the end face of the apical end of the implant; the implant breaks off from the implant extension at the constriction, along the longitudinal axis following the first section, wherein the second section, splined shaft section being further away from the implant than the first section, perpendicular to the longitudinal axis, an outer annular groove being designed to hold the implant extension by clamping the groove in the direction of the longitudinal axis.

Abstract: The present invention provides methods for treating or preventing asthma and associated conditions in a patient. The methods of the present invention comprise administering to a subject in need thereof a therapeutic composition comprising an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody.

Abstract: Embodiments of devices and methods for collecting gastrointestinal samples using a capsule-shaped device that is swallowed are provided.

Abstract: An end effector for stapling and cutting an anatomical structure includes an anvil, a cartridge, and a blade. The anvil has an anvil face and a plurality of staple pockets positioned on the anvil face. The cartridge has a cartridge face defining a cartridge blade channel, the cartridge being configured to retain a plurality of staples. Each of the plurality of staples comprises a first staple leg, a second staple leg, and a crown connecting the first and second staple legs and having a midpoint. Each of the plurality of staples comprises an open staple configuration and a closed staple configuration where a first portion of the first staple leg and a second portion of the second staple leg are bent relative to the crown such that the first portion of the first staple leg and the second portion of the second staple leg cross the midpoint of the crown.

Abstract: A protective member for a medical instrument includes a body portion having an inner side wall defining an interior, configured to receive at least a portion of the medical instrument. The body portion also includes a first end and a second end, wherein at least one of the first end and the second end is configured to at least partially close the respective first end and/or second end of the body portion. The at least partially closed first end and/or second end is configured to be opened for use of the medical instrument, such that the medical instrument can pass through both the first and second ends of the body portion during use, while the inner side wall surrounds a portion of the medical instrument. The body portion is configured for use during a medical procedure using the medical instrument, for example, as a tissue protector or a drilling guide.

Abstract: An apparatus, including a sterilely sealed package, and an electrode assembly sterilely sealed in the package, wherein the apparatus is configured to enable testing for an open circuit between two electrodes of the electrode assembly with the electrode assembly sterilely sealed in the package.

Abstract: An end effector for use to staple an anatomical structure of a patient during a surgical procedure includes an anvil and a cartridge. The anvil has an anvil face and a first staple pocket defined by the anvil face, where the first staple pocket comprises a first cup and a second cup for staple formation. The cartridge has a first staple and a first driver. The first staple, once deployed by the first driver and deformed by the first staple pocket, has a formed configuration in which a first portion of a first staple leg and a second portion of a second staple leg are bent relative to a crown and cross the midpoint of the crown and one of the first portion and the second portion overlaps the other of the first portion and the second portion.

Abstract: Packaging for a medical implant such as a hernia repair prosthetic material includes a carrier and a stiffener. The hernia repair prosthetic material is placed adjacent to the stiffener within the carrier. The carrier assembly is sealed within an outer pouch, such as a foil pouch, and sterilized. When the carrier is being removed from the pouch in preparation for surgery, the stiffener helps prevent the carrier assembly from contacting non-sterile portions of the pouch.

Abstract: A protecting device is provided, having two plates forming a rectangular protecting body for sandwiching, constraining and protecting a flexible pouch. The two plates are attached together at a peripheral margin. Each plate has an outer surface with ribs provided in a peripheral annular region of a covering part receiving the pouch, along the peripheral margin. The peripheral margin is mounted in supporting parts of a frame and sliding positioning members may be secured to the peripheral margin, so that the peripheral margin is guided and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar, at least at panel parts surrounded by the ribs. This allows for progressive conformational change of the protecting body when filling the pouch with biopharmaceutical product, while facilitating reverse displacement of the peripheral margin during draining operations.

Abstract: An aqueous storage solution for the storage of red blood cells, comprising an aqueous solution and at least one lipid, wherein the at least one lipid is effective in suppressing hemolysis in red blood cells and wherein the at least one lipid is emulsified within the aqueous solution.

Abstract: A freeze/thaw containment system is provided, having a protecting body and a flexible pouch protected by two plates of the protecting body. The two plates are attached together at a peripheral margin and form a rectangular protecting body. The peripheral margin is mounted in supporting parts of a stationary frame and sliding positioning members are secured to the peripheral margin, so that the peripheral margin is guided and allowed to be displaced inwardly during filling of the pouch, while the protecting body extends generally planar to sandwich and constrain the pouch in empty state of the pouch. This way of holding and retaining the protecting body allows for progressive conformational change of the protecting body due to the change in volume of the pouch when filled with a biopharmaceutical product, while facilitating reverse displacement of the peripheral margin during draining operations.

Abstract: A medical package containing a medical article, including: a support element comprising a hollow support tube and a support cap, wherein the support element includes a first chamber configured to enclose the medical article and wherein the support cap includes a support structure configured to hold the medical article captive; a stopper configured to be coupled to the hollow support tube in such a way that the support element has a grip part that protrudes from the stopper, the grip part of the support element configured to be held by a hand of a person; a hollow protective cover configured to be coupled to the stopper in such a way as to delimit, in cooperation with the stopper, a second chamber inside which there extends the grip part of the support element, the hollow protective cover configured to be separated from the stopper, wherein when the hollow protective cover is coupled to the stopper, a part of the stopper protrudes from the hollow protective cover, and is configured to form a grip end of the st

Abstract: A suture anchor comprises a tubular body having an axial bore therethrough and having one or more purchase enhancements on an exterior surface of the body adapted to enhance purchase of the body within a bone hole, such as threads. A lateral port passes through the body from the bore to the exterior surface and is formed of a slot entering the body from its proximal end. A length of suture for attaching soft tissue to bone passes down along the exterior surface over the one or more purchase enhancements, over a distal end of the body, up into the bore through and then back out of the bore and up along the exterior surface over the one or more purchase enhancements.

Abstract: A pharmaceutical product includes a delivery syringe comprising a plastic receptacle and an oxygen-tight envelope which envelopes the delivery syringe in an oxygen-tight manner, wherein the plastic receptacle is filled with an oxygen-sensitive active pharmaceutical ingredient fluid and an inner surface of the plastic receptacle is siliconized at least in sections.

Abstract: Embodiments of the invention are directed to a caddy configured to receive medical implants coupled to respective holders. The medical implants and holders may be oriented and/or located in the caddy based on one or more of size, shape, and other configuration of the medical implants and holders and the openings in the caddy through which the medical implants are received. Another embodiment of the invention incudes a medical implant having an implant body portion and a detachable marking portion that is connected to the implant body portion by a frangible region structured to provide selective separation of the implant body portion from the detachable marking portion upon application of a force or torque to the implant body portion, and the detachable marking portion including one or more markings that correspond to identifying information associated with features or characteristics of the implant body portion.

Abstract: An image surface protection structure of a painting capable of protecting the image surface layer of a painting from dirt and physical damage without impairing the original color or texture of the image surface of the paint layer is provided. An image surface protection structure of a painting comprising: a sealed space having an oxygen concentration of 4% or less, formed from a transparent hard plate and a gas barrier material; a painting placed in the sealed space, with the image surface of it facing the transparent hard plate.

Abstract: A packaging assembly is arranged for holding an article at a predetermined location relative to the packaging assembly in closed and open configurations of the packaging assembly. The packaging assembly includes at least two sections arranged to be secured in place relative to one another in the closed configuration of the packaging assembly, and move relative to one another in the open configuration of the packaging assembly. The at least two sections form an inner surface defining an attachment area for receiving the article. The packaging assembly includes at least one instruction area located along the inner surface and having indicia pointing to features of an article for placement in the packaging assembly and displayed relative to the attachment area.

Abstract: A towel set includes a towel holder and a plurality of towels stacked on one another. Each towel includes an opening, and the towel holder projects through the openings of the towels.

Abstract: A packaging insert configured to engage a portion of a surgical drape for locating the drape on a surgical robot arm, the drape comprising a drive transfer element for transferring drive between the robot arm and a surgical instrument, the packaging insert comprising a body and a retention portion engageable with the drive transfer element for retaining the drive transfer element in a desired position.

Abstract: A packaging system comprising a trough and a packaging element separate therefrom for closing the trough, the packaging trough having an outer cardboard structure folded or formed from corrugated board with an insert of a single or multiple layer plastic film, the inner side of each side wall of the cardboard structure being connected by material means to the insert only in its upper part of the side wall, the insert forming a substantially identically shaped, but loose contact surface with the lower part of the inner side of each side wall down to the base of the packaging trough and the trough having at least one gas venting opening.

Abstract: A press-type cosmetic bottle has a bottle body and a bottle cap. The bottle body comprises a bottle base and a bottle interface which are integrated as a whole. The bottle cap comprises an outer cap, a connector connected to the outer cap, and a middle ring fixed on the connector. The outer cap is provided with a press hole, and a press block is provided in the press hole. The bottle interface is held by the middle ring so that the bottle body is tightly connected to the bottle cap, and thus the bottle cap is not easy to get loose under the impact of an external force. The middle ring is configured to be pressed by the press block to make the middle ring deform, so that the middle ring disengages from the bottle interface, thereby removing the bottle cap from the bottle body.

Abstract: Control of expansion of a depth of field using a birefringent mask is realized in a more preferred aspect. A medical image processing apparatus includes a control unit that performs control so as to generate a corrected image by executing image processing on an image obtained by imaging a subject image of a patient acquired via an optical system including a birefringent mask and an acquisition unit that acquires information regarding an application situation of high-pressure steam sterilization processing on the optical system, in which the control unit controls the image processing according to the application situation of the high-pressure steam sterilization processing.

Abstract: The invention relates to a package (2; 3) for an object, preferably a medical object, the package comprising a bottom shell (21; 31); a top shell (22; 32) having a closure portion (24; 34) referred to as a “cap”, and a connection portion (23; 33) in the form of a hollow body and connected to the closure portion (24) by a hinge (25) to enable the closure portion (24; 34) to tilt relative to the connection portion (23; 33) in order to release access to the inside of the bottom shell (21; 31) through the connection portion (23; 33). The connection portion (23; 33) is provided with a stiffener element (290; 390) and a sealing strip (4; 4?) connects together the edges (241, 231) of the cap (24; 34) and of the connection portion (23; 33) that face each other over the entire length of said edges. Said connection portion (23; 33) of the top shell (22; 32) and of the bottom shell (21; 31) are two parts that are fastened to each other, preferably by bonding.

Abstract: A carrier strip having a plurality of areas for retaining anatomical pathology specimens may have a backing, a cover coupled to the backing along side regions located along opposite longitudinal edges of the carrier strip and along lateral intermediate regions positioned between each of the plurality of areas for retaining anatomical pathology specimens. The carrier strip may be configured to individually retain each of the anatomical pathology specimens in one of the plurality of areas for retaining anatomical pathology specimens between the backing and the cover. Diagnostic studies of anatomical pathology specimens may be facilitated by distributing a digital copy of an image of the specimen may be to a pathologist. A diagnosis may be received from the pathologist based on the digital image of the specimen.

Abstract: The present invention relates to a method for a street view service and an apparatus for performing same method. The method for a street view service may comprise: a step in which a street view service server receives a first path image for a first path from a first image processing apparatus; a step in which the street view service server generates first user provision information for the street view service for the first path on the basis of the first path image; and a step in which the street view service server transmits the first user provision information to a user apparatus.

Abstract: A defibrillator and a cover adhered to the defibrillator is provided. The defibrillator includes: a case; a handle at an upper surface of the case; a display panel at a front face of the case; and a plurality of buttons at the front face of the case. The cover covers the display panel and at least some of the buttons, and the cover includes a flexible plastic film.

Abstract: The lubricating oil composition of the present invention contains a base oil, a 2,6-di-tert-butylphenol (A), and at least one compound (B) selected from a benzotriazole compound and a sorbitan compound.

Abstract: An array of disposable pant-type gender-specific absorbent articles adapted for female and male users. The array has a first subarray including first and second sizes for female users; and a second subarray including third and fourth sizes for male users. Each absorbent article in the array has a transversely elasticised waist portion. At least one of the first and second size absorbent articles has a first circumferential length of the waist portion in a relaxed state and a second circumferential length of the waist portion in an extended state. At least one of the third and fourth size absorbent articles has a third circumferential length of the waist portion in a relaxed state and a fourth circumferential length of the waist portion in an extended state. The first circumferential length is smaller than the third circumferential length, and the second circumferential length is equal to the fourth circumferential length.

Abstract: A flexible package that can include first and second sidewalls. The first and second sidewalls being joined by a bottom portion and seams that define first and second sides. The package can have an opening opposite the bottom portion, a first plurality of magnetic regions, and a second plurality of magnetic regions. The first plurality of magnetic regions can be disposed on the first sidewall near the opening and include discrete magnetic regions. A second plurality of magnetic regions can be disposed on the second sidewall near the access opening and include opposed discrete magnetic regions. The second plurality of magnetic regions being opposite the first plurality of magnetic regions. The discrete magnetic regions and the opposed discrete magnetic regions can be magnetically engageable with a magnetic force to close the opening of the package in a configuration having M petals, where M is an integer from 2 to 8.

Abstract: An enclosure device is disclosed for delivering an implantable sheet-like support or repair device, such as ligament, tendon or other soft tissue support or repair device, to a surgical site. The enclosure device protects the support or repair device from unwanted adhesion and deformation during delivery and facilitates its optimal positioning at the injury or repair site where the support or repair device will be implanted. The enclosure device has a planar body foldable along one or more fold lines into at least two panels configured to contain the repair device between the panels; an optional cutout in one or more panels of the planar body at the panel edge opposite the fold line configured to expose a portion of the repair device; an optional positioning tab extending out from the fold line; and an optional securing mechanism to secure the enclosure device in a folded position. Methods of using the enclosure device are described.

Abstract: A corneal preservation and rehydration device includes a box body and a box lid (1), wherein the box body and the box lid are detachably connected. A corneal bracket (2) is provided in the box body for holding a cornea, wherein a surface of the corneal bracket for placing a cornea is a convex spherical surface (21), and a blocking portion (22) is arranged at the surrounding of the convex spherical surface (21) for preventing a cornea from dropping out.

Abstract: An automated system and method wrap the fastening ties around the body of a continuous stream of facemasks in a facemask production line. The facemasks are oriented such that each facemask has a leading pair of ties and a trailing pair of ties extending from a body in a conveying direction of the production line. At a wrapping station in the production line, the facemask body is subsequently clamped to prevent rotation of the body. The leading and trailing pairs of ties are grasped with a rotation device at each side of the conveyor that rotates around the body to wrap the leading and trailing pairs of ties to wrap around the body.

Abstract: The present application is directed to a packaging for a powdered explosive-detection training aid which may include first and second opposing flexible sheets heat sealed together along less than a periphery thereof and defining a storage compartment therebetween, wherein an unsealed portion of the periphery defines an opening to the storage compartment, wherein at least a portion of the first opposing flexible sheet is a semipermeable material permeable to a vapor emitted from the powdered explosive-detection training aid, with the second opposing flexible sheet being impermeable to the powdered explosive-detection training aid vapor; and a sealing member, wherein the sealing member is secured to the first opposing flexible sheet and, in a closing position, covers the semipermeable portion of the first opposing flexible sheet.

Abstract: The disclosure relates to a disposable hygiene article comprising an absorbent core which has first and second areas. The second area is located centrally in the middle portion of the article and extends longitudinally along a centre axis, transversally and symmetrically in a transverse direction towards each side edge of the core and in a thickness direction of the article. The second area protrudes outwards from a plane of the first area, and covers from 5-15% of a total area of the core. The first area surrounds the second area and covers the remainder of the total area of the core. The second area has grammage higher than grammage of the first area. The second area is integrated with the first area, and the second area is surrounded by a discontinuous embossing pattern which conforms to the shape of the second area of the core.

Abstract: An apparatus and a method are provided for a sterile staple implant kit that a surgeon may unpack and utilize during a surgery. The staple implant kit comprises a group of complementary surgery-specific instruments that are packaged in a sterile state. An instrument tray is configured to preserve the instruments in the sterile state until the staple implant kit is opened during the surgery. The instrument tray is configured to provide the surgeon with easy access to the instruments during the surgery. The staple implant kit comprises at least a staple inserter and a surgical staple suitable for being implanted in parallel holes drilled across a bone fusion or fixation site of a patient. The surgical staple preferably is loaded in a relaxed configuration into the staple inserter. A staple retention clip retains the surgical staple in the staple inserter until the staple is distracted during the surgery.

Abstract: A storage and transportation container for a radome of an aircraft is disclosed having a top wall, and bottom wall that are planar and parallel to one another, and a peripheral wall, wherein the top, bottom, and peripheral walls form an enclosure for supporting the radome within the container. The top wall has a closed curved outline and a surface of a dimension greater than that of the bottom wall having an outline which forms a parallelogram thus making it possible to receive the radome with its curved nose pointing downwards, and wherein the geometry of the container is matched to the form of the radome and of the hold.

Abstract: A “dry” packaging in which a prosthetic heart valve is packaged within a container with hydrogel that can be provided in many forms. Certain embodiments include hydrogel that is preloaded with glycerol or the like. The hydrogel regulates the humidity within the container through a diffusion-driven mechanism if a gradient of humidity between the inside and the outside of the hydrogel exists. Humidity regulation is important to prevent the tissue of the valve structure from drying out. When the partially-hydrated hydrogel is present within container, which is saturated with air of a predefined humidity, the water molecules from the air will be absorbed by the hydrogel if the air humidity is high (i.e. when the thermodynamics favor hydrogel hydration) or vice versa. Various embodiments are configured to also house at least a portion of a delivery device for delivering the prosthetic heart valve.

Abstract: A sanitary product disposal device includes an outer telescopic member and a flexible inner liner for holding a sanitary product to be dispensed. The outer telescopic member is adjustable between a collapsed position and an expanded position. The telescopic member has two sealable ends. The inner liner has a dispensing end at one of the two sealable ends. The dispensing end of the liner is configured to receive a sanitary product. The telescopic member is in the collapsed position before receiving a sanitary product, and in the expanded position after receiving the sanitary product.

Abstract: A reservoir for liquid medicament includes a first boundary portion and a second boundary portion forming at least one cavity to receive the medicament. The first boundary portion is flexible, while the second boundary portion is rigid. At least one of the first and second boundary portions is a transparent boundary portion covered by an opaque cover which is at least partially detachable from the transparent boundary portion.

Abstract: An oxygen-mixing cosmetic container is proposed. In the cosmetic container, the structure of an oxygen supply cap, which is installed beneath an oxygen cap and a cosmetic container body, is improved such that, when the oxygen supply cap is coupled, oxygen is ejected simultaneously, components of the oxygen supply cap are simplified such that, besides reducing the material cost, the same can be assembled more efficiently, and the oxygen capsule, which is mounted on the oxygen supply cap, can be easily replaced.

Abstract: A medical implant packaging assembly having an outer tray, an inner tray and a retainer. An implant which may include a hydrated tissue graft may be positioned within the packaging assembly. The inner tray is formed from a moisture barrier material whereby the implant may be maintained in a hydrated state, even if the implant is not immersed in fluid within the packaging assembly, thereby avoiding need for rehydrating steps that are required for dehydrated and/or cryopreserved implants prior to or during surgery. The outer tray and inner tray and a retainer are also made of transparent materials, enabling medical personnel to view the implant through these packaging components prior to and during surgery.

Abstract: A packaging assembly is arranged for holding an article at a predetermined location relative to the packaging assembly in closed and open configurations of the packaging assembly. The packaging assembly includes at least two sections arranged to be secured in place relative to one another in the closed configuration of the packaging assembly, and move relative to one another in the open configuration of the packaging assembly. The at least two sections form an inner surface defining an attachment area for receiving the article. The packaging assembly includes at least one instruction area located along the inner surface and having indicia pointing to features of an article for placement in the packaging assembly and displayed relative to the attachment area.

Abstract: Instruments and related methods for breaking reduction tabs are disclosed herein, e.g., for breaking reduction tabs of a bone anchor or other implant. In some embodiments, the instrument can be configured to minimize the space needed to operate the instrument. For example, the instrument can be configured to receive a reduction tab that is to be broken while the instrument is coaxially positioned with respect to a bone anchor receiver to which the reduction tab is attached. As another example, the instrument can have a maximum outer transverse dimension that is less than, equal to, or only slightly greater than a corresponding dimension of a bone anchor from which a reduction tab is to be broken. Guide rods for positioning a tab breaker instrument over a reduction tab are also disclosed.

Abstract: A packaging structure for at least one article includes a pair of generally rectangular support structures with front, side, rear, and interior walls. The walls divide the rectangular support structure into a plurality of triangular sections. The front and interior walls contain a least one opening configured to correspond with the configuration of the article to hold and secure the article in place. The packaging structure is created from a rectangular blank made of foldable material that has a plurality of spaced vertical fold lines, panels, and aligned openings each configured to correspond with the configuration of the article. The packaging structure is formed by folding the blank along the fold lines and securing the blank in the folded condition.

Abstract: The invention provides a syringe for dispensing a drug (1), comprising: a rigid syringe body, —a first container (2), in contact with and enclosing the drug; and a second container (3), enclosing the first container, the second container being less gas permeable than the first container, wherein the second container partially or fully forms the rigid syringe body or is held within the rigid syringe body. The invention preserves the drug but allows the drug to be easily accessed without the need for a user to remove a gas barrier structure as a separate action in addition to the other actions needed to deliver the drug.