Abstract: A foldable multi-purpose container filler includes a sheet of material that may be reversibly convertible between a compact form for storage or packaging and an expanded form to fill a container opening (e.g., bag, drinkware, vase, etc.). The container filler includes fold lines or creases that dictate the compact form and the expanded form and allow for reversible conversion between the forms. In addition, the container filler includes connectors for securing the container filler to a container, as well as a base to support the container filler upright on a surface absent a container.

Abstract: A tamper evident package comprises a blister assembly defining at least one cavity, the opening of the at least one cavity being at least partially closed by a membrane. A sleeve housing the blister assembly is provided, the sleeve having a top side and a bottom side, the bottom side having a contact window that is aligned with the cavity. In addition, a package integrity feature is applied to the bottom side and covers the contact window. The package integrity feature is further applied to the membrane covering the cavity through the contact window.

Abstract: A blister package is provided that includes a base made from cyclic olefin copolymer (COC) and a lidding film that includes polyolefin layer(s) or a combination of polyolefin and COC layers, that allows both the lidding film and base to be recycled in a single plastic waste stream.

Abstract: Single oral solid dosage form comprising an immediate release first dosage composition having at least two antibiotic agents and a delayed release second dosage composition having a proton pump inhibitor are provided herein. The single oral solid dosage form according to some aspects of the invention can be used for the treatment of disorders associated with infection by H. pylori or the prevention of recurrence of disorders associated with infection by H. pylori.

Abstract: Child-resistant packaging (1), which comprises at least one blister card (10), known per se, with a carrier film (20) and a cover film (30), wherein the carrier film (20) forms, with at least one blister cavity (25) for receiving a packing product (40), a top side (11) of the blister card (10), and the cover film (30) is connected extensively to the carrier film (20), closes the blister cavity (25) filled with the packing product (40), and forms an underside (12), located opposite the top side (11), of the blister card (10).

Abstract: A blister pack configured to sealingly enclose at least one active member and product includes a backing having a first side and an opposing second side. Each of the first and second side is flat or planar. The blister pack can also include a cover having a first side and an opposing second side. At least a portion of the second side of the cover is adhered to the first side of the backing to form a sealed package for containing product. The cover can include at least one blister. Each blister can have a dome portion and a base portion. The base portion can surround the dome portion. The base portion can extend outwardly beyond the first side of the cover.

Abstract: Disclosed is a method and apparatus for transporting and dispensing medications for a patient according to a medication schedule for the patient. A smart container from a pharmacy is received at the patient's site and the container is checked to make sure that the container was delivered to the correct patient site. The smart container contains a memory device that contains identification information of the patient, dosage and treatment instructions for the patient. This information and the medication were checked for compatibility before the smart container was delivered. The identity of the patient at the patient's site is then checked and the patient performs on or more biometric tests before the medication is dispensed by the smart container. Upon taking the medication and providing video proof thereof, the smart container is returned to the pharmacy.

Abstract: A seal for use with a container for storing and dispensing consumer products is described. The seal includes a cover layer having pre-formed lines of separation defining one or more releasable portions, an adhesive layer on the cover layer, and one or more patches on the adhesive layer. Each patch is associated with a respective one of the releasable portions 6 and consists of a hot melt polymer. The hot melt polymer can be applied to the adhesive layer using a suitable coating or spraying process.

Abstract: A multi-layer film structure for use in forming blister packaging. The multi-layer structure includes a first polymeric layer having a first surface and a second surface, the first polymeric layer comprising a metalized polyethylene teraphthalate, a second polymeric layer having a first surface and a second surface, the first surface of the second polymeric layer disposed adjacent the second surface of the first polymeric layer, the second polymeric layer comprising a cyclic olefin or a homopolymer of chlorotrifluoroethylene, and a third polymeric layer having a first surface and a second surface, the first surface of the third polymeric layer disposed adjacent the second surface of the second polymeric layer, the third polymeric layer comprising polypropylene or polyvinyl chloride. A method of making a multi-layer film structure and a packaging structure are also provided.

Abstract: A container assembly includes an outer cover and a container. The front of the outer cover includes a minor front flap located on an interior surface thereof. The front of the container includes at least one minor exterior flap. The container is received in the open end of the outer cover, The container forms an aperture. The minor front flap of the outer cover and the minor exterior flap of the container are generally aligned in a plane in a closed position of the container assembly to prevent or inhibit opening thereof. The outer cover initially moves with respect to the container by pushing the front of the container and moving the outer cover such that the minor front flap of the outer cover clears the minor exterior flap of the container allowing the container assembly to be moved from the closed position to an open position.

Abstract: A child-resistant medication container assembly that includes a blister card including a plurality of compartments each configured to support a dosage of medication, and a puck including a body portion, a recess that defines a partition wall in the body portion, and a plurality of openings defined in the partition wall. Each opening corresponds to one of the plurality of compartments in the blister card. The assembly further includes a carton including a first wall opposite a second wall. An access opening is defined in the first wall and a plurality of perforations are defined in the second wall. The access opening is sized to provide access to the plurality of compartments, and each perforation corresponds to one of the plurality of compartments in the blister card.

Abstract: A multi-layer product as a seal includes a cover layer having an adhesive layer and a backing layer with a release layer. The cover layer has a first part including one or more releasable portions, each having an associated patch. The backing layer has a pre-formed line of separation that extends across the seal from the first edge to the second edge and separates the backing layer into a first part and a second part. The second part of the backing layer includes at least one removable portion at an edge thereof. Each removable portion is defined by one or more pre-formed lines of separation. The cover layer has a second part including at least one flap portion each of which is substantially coincident with a respective one of the removable portions and defined by one or more pre-formed lines of separation in the second part of the cover layer.

Abstract: Disclosed is a medicament dispenser (1) for delivering a medicament (9, 53) to a user (2), the medical dispenser (1) comprising one or more internal storages (3, 52) for storing one or more medicaments (9, 53); a dispensing unit (10, 101) configured to access said one or more internal storages (3, 52) and dispense the medicament (9; 53) based on a predefined dispensing protocol (18); a control unit (13) comprising a user recognition unit (12, 19), adapted to collect user authentication data (76); and a communication module (14), configured to send/receive said user authentication data (76) and a delivery control data (16) associated to said predefined dispensing protocol (18) to/from a remote server (15); wherein said control unit 5 (13) is configured to enable/disable said dispensing unit (10, 101) based on said user authentication data (76) and said delivery control data (16).

Abstract: An arrayer for constructing a tissue array includes a recipient block holder having an upper face, a void for accommodating a tissue recipient block, and a guide plate configured to engage with the upper surface of the recipient block holder. The guide plate includes an array of through openings aligned with the void of the recipient blocking holder. The recipient block holder and the guide plate are configured to be secured to each other through securing elements. A kit including the arrayer, and punch pens for creating holes in the recipient block and for transferring tissue to the recipient block holder, is also provided. Methods of using the arrayer and the kit are also provided.

Abstract: A packaging comprising: (a) an outer card having one or more cavities; and (b) one or more blister cards housed within the one or more cavities, wherein the one or more blister cards are removable from the one or more cavities so that the one or more blister cards are disposable separate from the outer card.

Abstract: A drug-filled synthetic resin ampule includes an ampule body and a drug 8 filled in the ampule body. The ampule body includes a tip-side sealing portion, a hollow portion, and an annular breakable portion provided between the tip-side sealing portion and the hollow portion. The tip-side sealing portion includes a flat plate portion for grasping formed at an upper portion thereof, and an internal ceiling portion exposed to the interior of the hollow portion. The breakable portion includes an annular smallest diameter portion, and the smallest diameter portion is located near an annular circumferential edge portion of the internal ceiling portion and is located above the annular circumferential edge portion of the internal ceiling portion.

Abstract: A liquid container includes a container portion and a lid. The container portion includes a plurality of storage portions separated by at least one partition rib and storing liquid respectively in an isolated state. The lid bonded with the container portion so as to cover an opening region of the container portion. A plurality of project portions engaging with the partition rib so as to sandwich the partition rib from both sides of the partition rib is integrally molded with the lid. In a state in which the partition rib is engaged with the project portions, a bonding portion is filled with bonding resin so as to seal a cavity between an edge end of the partition rib and the lid and a cavity between an edge end of an outer circumference of the container portion and the lid.

Abstract: Systems and methods for an automated measurement utility are disclosed. Image analysis is used to determine a quantity of items in a stack of items. The quantity of items can be determined further based on item information and location awareness information. The quantity of items can be used to determine resource requirements, predictive workloads, and to improve item processing operations.

Abstract: Eflornithine is an agent that can be used to treat glioma, especially glioma of WHO Grade II or Grade III such as anaplastic glioma. Eflornithine can suppress or prevent mutations in glioma which can cause the glioma to progress to a higher grade. The present invention describes pharmaceutical compositions that contain eflornithine or a derivative, analog, or prodrug thereof. The pharmaceutical compositions can be prepared in a number of dosage forms and may contain another therapeutically active agent or an agent that enhances the therapeutic activity of the elformithine or the derivative, analog, or prodrug thereof. The present invention also describes a kit that includes dosage forms of pharmaceutical compositions according to the present invention.

Abstract: A simple and quick verification of the authenticity of a blister of elements, such as pills in the pharmaceutical industry, is provided. The pills packaged in a blister can be authenticated using mobile imaging devices such as a mobile smartphone. Generally speaking, an image of the pills and their differentiating physical characteristics in the blister is acquired and compared to at least one code which is marked on the blister itself. This code may also be encrypted. A dedicated software application on the mobile smartphone can be used to decrypt the code and compare the code to the image of the pills in the blister, to thereby evaluate authenticity of the blister and its contents.

Abstract: A seal that forms part of a container for storing and dispensing consumer products is provided. The container can be used for the packaging of pills, tablets or capsules, or as a multi-cavity container for organizing and storing mixed medication for subsequent dispensation according to a predefined dosage regimen. The seal includes a cover film and a barrier film. The cover film has pre-formed lines of separation defining a removable portion per cavity. The barrier film is secured to the cover film by a layer of peelable adhesive and has pre-formed lines of separation defining the periphery of a barrier patch per removable portion. The cover film includes a tamper-indicating line of separation close to an edge of the cover film that is designed to tear if an attempt is made to peel the cover film away from the tray to expose one or more of the cavities.

Abstract: A multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber serves to hold an item to be dispensed and is surrounded by a flange. A closure member, in the form of a respective portion of a frangible cover sheet, is adhesively secured to the flange of each compartment unit. Each compartment unit includes at least one foldable tab in a corner of its flange, which can be folded down to enable the closure member to be removed from the compartment unit after the compartment unit is separated from other compartment units of the package.

Abstract: Disclosed is a medication dispensing device adaptable to receive a medication dispensing tray, the tray having a slidable overlapping foil layer to incrementally expose the compartments of the medication dispensing tray. The dispensing device delivers the medication dispensed from the tray compartments to the patient through a funnel and staggered rotatable cup system to individually dispense each of the compartments of the tray.

Abstract: Disclosed are package assemblies and methods of making the same, wherein the assemblies can include, among other elements, an outer carton defining an interior product storage compartment; an inner product support card slidably received within the product storage compartment; the inner support card having a main body portion and one or more flaps; and one or more primary product packages, each being secured to one of the one or more flaps.

Abstract: A rigid holding container has a flexible cover sheet extending over the holding area for sealing the contents. The container has a wide, flat perimeter lip which provides a firm base for the seal between the cover sheet and the container. A breaching bubble is formed in the seal, under the cover and over the perimeter lip. The consumer breaches the bubble by pressing the bubble against the lip between the thumb and forefinger. The pressure compresses the air in the bubble causing the bubble to expand laterally. The expanding bubble breaches along the perimeter of the lip, producing a peel flap of flexible cover material. The consumer pulls the peel flap while holding the rigid container down, to remove the cover sheet.

Abstract: Methods and systems for a drug supply with an associated dosing regimen are described. Sachets may to store at least one pharmaceutical drug. A dosing bag holds at least one sachet and stores a specific pharmaceutical dose. Dosing bag assemblies are formed from one or more than one dosing bag and can be connected together to form a package. A book may be formed to include a plurality of drug containing bags or bag assemblies, which may form pages in the booklet. The dosing bags may be removed from the pages to allow the patient to take the specific pharmaceutical dose with them. alternatively, the dosing bag may be opened in the booklet and the specific pharmaceutical dose may be taken.

Abstract: A cartridge and method to authorize and adjust the operation of an oral care appliance are disclosed. The oral care appliance along with the cartridge may be used for cleaning, whitening, removing plaque, or in other general oral care applications for providing oral care hygiene.

Abstract: A package includes a housing, a container, and a coupling system. The housing defines a first internal volume and includes first lateral walls that define a first through opening further defined by a first edge. The container defines a second internal volume and is configured for housing one or more products. The container includes second lateral walls that define a second through opening further defined by a second edge, the second through opening being configured to permit insertion and withdrawal of the one or more products from the container. The container is adjustable to a first configuration in which the container is at least partially disposed within the housing and a second configuration in which the container is at least partially disposed outside of the first internal volume. The coupling system is configured to secure the container to the housing.

Abstract: An applicator including a body with a hair separator and an application aperture. The hair separator and the application aperture are structured to expose a portion of the animal's skin so that the user can see how much of a treatment is being applied and ensure the treatment is applied substantially to the animal's skin.

Abstract: Devices and methods manually open glass ampules within the devices. One device may include a holder having at least one deformable side wall, a supporting element, and at least one strainer/filter arranged below the holder so that the content of the opened glass ampule may flows therethrough. A first lever of the device may pivot around a first axis and a free end of the first lever may be pressed against the deformable side wall of the holder. A second lever of the device may pivot around a second axis that may divide the second lever into a short lever arm and a long lever arm. The short lever arm may be pressed against the first lever and a glass ampule may be broken open by pressure of the free end of the first lever.

Abstract: Blister package having a novel pull tab construction that enables opening of each individual product cavity of the blister package. The pull tab is formed by breaking off a portion of a base substrate along a notched line that includes a series elongated severed portions extending completely through the thickness of the base substrate, separated by the unsevered (connected) portions. The notched line can be formed in the same mold that is used to form the recessed product cavity of the base substrate, thereby reducing the number of manufacturing steps and equipment, resulting in a significant cost savings during manufacture. The new notch line configuration eliminates the problems of the prior art with score depth achievement and consistency, while providing a reliable breakable line, and enable less brittle (non-PVC) polymers to be used. It also eliminates the problem with knife wear that prevented score depth achievement and consistency with non-PVC materials.

Abstract: The technology disclosed herein includes a packaging apparatus including an outer sleeve, an inner sleeve, and at least one locking mechanism configured to lock the inner sleeve inside the outer sleeve. In some implementations, the locking mechanism is an interior sliding mechanism, which locks the inner sleeve in its entirety in the outer sleeve. In some implementations, the locking mechanism is an interior sliding mechanism, which permits the inner sleeve to move partially out of the outer sleeve. In some implementations, the locking mechanism includes a spring, a tab, a flap, a key, a magnet lock, or other locking component. In some implementations, the inner sleeve includes a pull tab for removal of the inner sleeve from inside the outer sleeve.

Abstract: A pill container has a body, multiple lids, and multiple resilient pushing bars. The body has a front wall, a rear wall, multiple compartments, and multiple locking buttons. The locking button are formed on the front wall of the body and aligned respectively with the compartments. The lids are connected pivotally to the rear wall of the body to selectively close the compartments respectively and are engaged detachably with the locking buttons respectively. Each lid has an inner surface facing a corresponding one of the compartments of the body. The resilient pushing bars are mounted on the rear wall of the body and respectively abut against the inner surfaces of the lids.

Abstract: Disclosed is a medication dispensing tray adapter for attachment to a medication dispensing tray, the tray adapter having a slidable overlapping foil layer to incrementally expose the compartments of the medication dispensing tray. The tray and tray adapter may be combined into a medication dispenser apparatus that delivers the medication dispensed from the tray compartments to the patient.

Abstract: Disclosed are package assemblies and methods of making the same, wherein the assemblies can include, among other elements, an outer carton defining an interior product storage compartment; an inner product support card slidably received within the product storage compartment; the inner support card having a main body portion and one or more flaps; and one or more primary product packages, each being secured to one of the one or more flaps.

Abstract: The present teaching relates to a packaging unit for one or more individually removable products, in particular tablets, including a blister packaging and a bag-type outer packaging, in which the blister packaging is enclosed. The blister packaging is movably arranged in the outer packaging and can be brought into at least one removal position, in which the removal of at least one of the products is enabled. The blister packaging has at least one positioning element, and the outer packaging has at least one receiving element for the positioning element, wherein the positioning element arranged in the receiving element defines the removal position.

Abstract: The present invention encompasses a system which enables arrangements of various shapes and sizes to be packaged for delivery and transport utilizing a standard container. Systems in accordance with the present invention utilize a first and second container each capable of receiving a foam base utilized in the creation of an arrangement of a predetermined size. The first and second containers are of different sizes so that one may nest inside the other. Once nested, the containers form a locking engagement with one another.

Abstract: A child-resistant package is provided having a hollow carton with opposed front and rear walls and a separate blister card having a plurality of separate, spaced-apart hollow blister compartments contained therein. The front wall of the hollow carton comprising a structure including an exterior wall panel having a plurality of openings, gates, or pull tabs and an interior wall panel adhesively secured to the exterior wall panel. The interior wall panel of the front wall has a plurality of chads aligned between the openings and blister compartments. The rear wall of the hollow carton comprising a structure including an exterior wall panel having a plurality of separate, openings and an interior wall panel adhesively secured to the exterior wall panel. The interior wall panel of the rear wall having a plurality of break-away chads located directly between the blister compartments and the openings.

Abstract: A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.

Abstract: An oral care dispenser for dispensing an oral care fluid. The dispenser may include: a housing defining a cavity; a wall in the cavity, the wall dividing the cavity into first and second reservoirs of variable volume, the first reservoir containing an oral care fluid; a first opening in fluid communication with the first reservoir, wherein the oral care fluid is dispensable from the dispenser through the first opening; a second opening in fluid communication with the second reservoir; and an actuator operable to dispense the oral care fluid through the first opening. In an embodiment, the oral care dispenser may form a part of a system that includes an oral care implement, such as a toothbrush.

Abstract: A web of cleaning products and a method of manufacturing the same is disclosed. The web includes a carrier sheet having a plurality of depressions each filled, and in direct contact with, at least one cleaning composition. A plurality of internal lids that correspond with the plurality of depressions are sealed to the carrier sheet in a manner covering the plurality of depressions. Additionally, a plurality of external lids that correspond with the plurality of internal lids are sealed to the carrier sheet and cover the plurality of internal lids. The carrier sheet and external lids may be made of a water-resistant material, and the internal lids may be made of a water-soluble material. In one embodiment, the internal lids may be omitted, and instead the depressions be filled with water-soluble pouches, each of which contains a respective dose of a cleaning composition.

Abstract: A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.

Abstract: Methods and compositions for treating inflammatory bowel disease involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in the absence of the probiotic. The practice of the invention may reduce or eliminate the use of immunosuppressants in the treatment and management of IBD.

Abstract: A medicine packaging PTP sheet capable of protecting a pocket from pressurization by external force in a combined state in which the medicine packaging PTP sheet has a first sheet in which a pocket capable of accommodating a medicine and a projecting convex portion each are projected from the upper surface and a second sheet which is attached to the lower surface of the first sheet and blocks an opening of the pocket. A first distance L1 from the upper surface of the first sheet to the projection end of the convex portion is longer than a second distance L2 from the upper surface of the first sheet to the projection end of the pocket.

Abstract: A blister package including an outer sleeve and a blister receptacle, the blister package having retention panel supporting mechanisms proximate an end of the blister receptacle to support the blister package in the outer sleeve when the blister package is almost completely withdrawn from the outer sleeve and may include one or more locking mechanisms to prevent unwanted opening of the blister package or disengagement of the blister package from the outer sleeve.

Abstract: Disclosed is a tamper resistant blister pack having a paperboard assembly attached to, and surrounding, at least a part of a flange on the blister (window element). An upper ply of the assembly is attached to an upper side of the flange. Additionally, although in some instances not necessary, a lower ply is attached to the lower side of the flange. The plies of the assembly have a paperboard layer, an upper film layer laminated to an upper side of the paperboard layer and a lower film layer laminated to a lower side of the paperboard layer. These layers and their attachment to the blister provide tear resistance without crisscrossing film orientation. Methods of making the pack are also disclosed.

Abstract: Receptacle of gel card type comprising a body, formed in which are several adjacent wells, initially sealed by a cover having a length and a width. The cover has at least one precut between two adjacent wells so as to form at least one cover portion sealing at least one of the wells of the receptacle.

Abstract: Multiple blister pack (1) for button batteries comprising a blister foil (10) designed to provide individual storage cups (12) of center (C) and diameter (D) for receiving a button battery, and individual closure regions (13) for each said individual storage cup (12). Each closure region (13) receives a closure element (4), and the individual storage cups (12) are arranged on the blister foil (10) according to a matrix pattern with at least two columns. Each closure region (13) surrounding each individual storage cup (12) are mutually separated by column and row tearing lines (2,2?). The closure element (4) and/or the closure region (13) is provided with tracking information concerning the battery stored in said individual storage cup (12) and the centers (C) of the individual storage cups (12) are spaced apart of a distance equal to twice the diameter (2*D) of the individual storage cup (12) from each other along each column of said matrix, within a tolerance of 1 millimeter.

Abstract: A multichamber container and a method of preparing medical fluids having concentrates which make a contribution toward the electrical conductivity of the solution and are additionally prepared from concentrates which do not make a contribution toward the electrical conductivity of the solution. The multichamber container is configured by dividing solution components into multiple chambers, so that following the dissolving due to breaking open of the first chamber border of a solution component, which makes a contribution toward the electrical conductivity of the medicinal solution, another chamber border of another solution component which does not make any contribution toward the electrical conductivity of the solution is broken open.

Abstract: The invention relates to a system for opening a medical blister package which is easy and convenient to open for people of all level of ability and dexterity. Its design allows for selective access to the blisters by following a predetermined opening sequence, therefore minimizing involuntary wrong up taking of medicine due to patient errors as wrong sequential opening is not achievable by involuntary mistakes.