Pneumatic Or Liquid Stream Feeding Item Patents (Class 209/906)
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Patent number: 8657121Abstract: Disclosed herein is a microchip including a substrate and a sample flow path within the substrate. The sample flow path includes a changing flow path and a microtube connected to the changing flow path. The changing flow path is configured to change a cross sectional shape of the sample flow path from a quadrangular shape at a first end to a circular shape at a second end. The microtube is connected to the second end of the changing flow path and is disposed within the substrate.Type: GrantFiled: April 28, 2011Date of Patent: February 25, 2014Assignee: Sony CorporationInventors: Masataka Shinoda, Takeshi Matsui, Akiko Tsuji, Takeshi Yamasaki, Shoji Akiyama
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Patent number: 8567608Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: July 8, 2009Date of Patent: October 29, 2013Assignee: Cytonome/ST, LLCInventors: Manish Deshpande, John Gilbert
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Patent number: 8408399Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: June 13, 2011Date of Patent: April 2, 2013Inventors: Sebastian Böhm, John R. Gilbert, Manish Deshpande
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Patent number: 8387803Abstract: A particle sorting cell (10) comprises a cavity (12), an inlet (16) of a fluid flow (14) into the cavity, a first outlet (18) of a first part (22) of the fluid flow out from the cavity and a second outlet (20) of a second part (24) of the fluid flow out from the cavity. The second outlet is displaced from the first outlet in a first direction (Y) transverse to the flow direction (X). An acoustic generator (40) is arranged to apply an acoustic standing wave. The standing wave is transverse to the flow direction as well as to the first direction. A controller (42) is arranged to control a selective operation of the acoustic generator in dependence of an input data signal (44) associated with a particle (32) comprised in the fluid flow. The particle (32) can selectively be separated into the first outlet or the second outlet.Type: GrantFiled: August 26, 2008Date of Patent: March 5, 2013Assignee: GE Healthcare Bio-Sciences ABInventors: Sara Thorslund, Linda Johansson
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Patent number: 8281935Abstract: An automated machine is used to handle and manipulate individual pieces of particulate matter. The particulate matter is contained in a bin. The machine operates to pick single individual pieces of the particulate matter from the bin. The picked individual pieces are then conveyed for further handling. Pneumatic transport is primarily used for the conveying operation. One aspect of the handling involves individually weighing each piece of the picked particulate matters. Another aspect of the handling involves sorting the individual pieces of particulate matter into a plurality of receptacles. Yet another aspect of the handling involves both weighing and then sorting the individual pieces of particulate matter, wherein the sorting operation may be performed based upon the measured weight of each piece.Type: GrantFiled: April 29, 2011Date of Patent: October 9, 2012Assignee: Monsanto Technology LLCInventor: Kevin L. Deppermann
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Patent number: 8061527Abstract: A grain classifying device for accurately classifying the grains of uniform length, and an adhesive containing grains classified by the device and capable of connecting electrodes under a low pressure and being applicable to electrodes arranged in fine pitches. The grain classifying device (1) includes a dispersing means (2) for dispersing a plurality of grains (P). A grain orienting means (3) orients each of the dispersed grains in a transfer direction (X) of the grains (P) while spacing the grains apart from one another in the transfer direction (X) of the grains. A grain length measuring means (4) measures the length of each of the grains (P) oriented in the transfer direction (X). A grain separation means (5) separates the grains (P) having a predetermined length based on data related to the lengths of the measured grains (P).Type: GrantFiled: September 22, 2006Date of Patent: November 22, 2011Assignee: Sumitomo Electric Industries, Ltd.Inventors: Keiji Koyama, Tetsuya Kuwabara, Masaru Haga, Hideki Kashihara
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Patent number: 8047381Abstract: A grain classifying device for accurately classifying the grains of uniform length, and an adhesive containing grains classified by the device and capable of connecting electrodes under a low pressure and being applicable to electrodes arranged in fine pitches. The grain classifying device (1) includes a dispersing means (2) for dispersing a plurality of grains (P). A grain orienting means (3) orients each of the dispersed grains in a transfer direction (X) of the grains (P) while spacing the grains apart from one another in the transfer direction (X) of the grains. A grain length measuring means (4) measures the length of each of the grains (P) oriented in the transfer direction (X). A grain separation means (5) separates the grains (P) having a predetermined length based on data related to the lengths of the measured grains (P).Type: GrantFiled: June 17, 2010Date of Patent: November 1, 2011Assignee: Sumitomo Electric Industries, Ltd.Inventors: Keiji Koyama, Tetsuya Kuwabara, Masaru Haga, Hideki Kashihara
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Patent number: 8002117Abstract: A method and apparatus for sorting a gas-driven stream of generally flat and light-weight articles of varying dimensions execute a, preferably optical, inspection and upon so finding a non-conforming article remove the latter from the stream. In particular, the inspection and the sorting are executed during a substantially straight movement of the articles. The removing is executed through gas driving in a direction substantially transverse to the straight movement. Advantageously, the inspection is preceded by orienting the articles through a centrifugal force that orients said articles against an inclined wall in a transition to the vertical movement. Also airflow means (83,84) can be used to confine the articles in a thin layer.Type: GrantFiled: October 19, 2005Date of Patent: August 23, 2011Assignee: Comas, S.p.A.Inventors: Thomas Marinus Antonius Van de Laak, Mario Martin, Robertus Cornelis Van Hoek
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Patent number: 7963399Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: August 7, 2009Date of Patent: June 21, 2011Assignee: Cytonome/ST, LLCInventors: Sebastian Böhm, John R. Gilbert, Manish Deshpande
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Patent number: 7934600Abstract: An automated machine is used to handle and manipulate individual pieces of particulate matter. The particulate matter is contained in a bin. The machine operates to pick single individual pieces of the particulate matter from the bin. The picked individual pieces are then conveyed for further handling. Pneumatic transport is primarily used for the conveying operation. One aspect of the handling involves individually weighing each piece of the picked particulate matters. Another aspect of the handling involves sorting the individual pieces of particulate matter into a plurality of receptacles. Yet another aspect of the handling involves both weighing and then sorting the individual pieces of particulate matter, wherein the sorting operation may be performed based upon the measured weight of each piece.Type: GrantFiled: March 15, 2006Date of Patent: May 3, 2011Assignee: Monsanto Technology LLCInventor: Kevin L. Deppermann
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Patent number: 7741574Abstract: A separator and related separation methods are for intended use in separating particles having a selected charge from a particle mixture entrained in or carried by a fluid flow. The separator comprises a tubular, elongated body for receiving the fluid flow. At least one and preferably a pair of electrodes may be provided to create an electric field in at least a portion of the body through which the fluid flow passes, and at least one partition defines first and second channels for receiving the flow downstream of the portion of the body including the electric field. In one embodiment, the electrode is oriented such that a direction of gravity acting on particles having a selected charge passing through the electric field directs the selectively charged particles towards the first or second electrode. A system may incorporate the separator, along with a diffuser.Type: GrantFiled: May 2, 2006Date of Patent: June 22, 2010Assignee: University of Kentucky Research FoundationInventors: John M. Stencel, Tapiwa Zabron Gurupira
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Patent number: 7584857Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: August 7, 2006Date of Patent: September 8, 2009Assignee: Cytonome/ST, LLCInventors: Sebastian Böhm, John R. Gilbert, Manish Deshpande
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Patent number: 7553110Abstract: An appearance inspecting apparatus includes a parts feeder aligning rubber stoppers in tandem by torsionally vibrating a bowl having a spiral track formed therein, an air conveying portion conveying the rubber stoppers aligned in tandem by blowing compressed air thereto, first and second conveying tables conveying rubber stoppers by suction-holding a surface not to be inspected of the rubber stoppers, an inspecting portion inspecting a surface to be inspected of the rubber stoppers conveyed by the first and second conveying tables, and a selecting portion sorting out rubber stoppers that are determined to be defective, in accordance with the result of inspection by the inspecting portion. Objects to be inspected having a complicated shape are aligned preliminarily by using a vibration parts feeder, while highly accurate appearance inspection is conducted.Type: GrantFiled: January 6, 2003Date of Patent: June 30, 2009Assignee: Daiichi Jitsugyo Viswill Co. Ltd.Inventors: Mitsuhiro Minami, Koji Tsutsumi, Hiroki Makino, Norio Oita
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Patent number: 7497334Abstract: A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.Type: GrantFiled: December 7, 2007Date of Patent: March 3, 2009Assignee: Hewlett-Packard Development Company, L.P.Inventors: David Tyvoll, Winthrop D. Childers, Paul Crivelli
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Patent number: 7389879Abstract: A device for sorting particles. The device may include a channel structure that defines a channel having an inlet and first and second outlets. The device also may include first and second transport mechanisms. The first transport mechanism may be configured to create a particle stream of first particles and one or more second particles. Each particle may move along the channel from the inlet toward the first outlet and may be disposed in a fluid supported by the channel structure. The second transport mechanism may be configured to be pulse-activated to selectively move at least one of the second particles from the particle stream and toward the second outlet.Type: GrantFiled: January 21, 2004Date of Patent: June 24, 2008Assignee: Hewlett-Packard Development Company, L.P.Inventors: David Tyvoll, Winthrop D. Childers, Paul Crivelli
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Patent number: 7232687Abstract: An optical illumination and monitoring subsystem controls the operation of a flow cytometer having a carrier fluid that flows along a channel coupled to a droplet generator, which controls a point at which droplets break off from the carrier fluid, and a droplet sorter that is operative to cause selected droplets to be sorted along one or more droplet travel paths. The subsystem is operative to illuminate a respective droplet monitoring location along each of one or more droplet travel paths with a respective beam of light, such as that sourced from a common laser. In response to backscatter reflection from a droplet passing through the respective beam of light at a respective droplet monitoring location, the amplitude of the beam of light is increased. Then the droplet is monitored for the presence of a particle therein exhibiting detectable fluorescence as a result of the increase in the amplitude of the respective beam of light.Type: GrantFiled: April 7, 2004Date of Patent: June 19, 2007Assignee: Beckman Coulter, Inc.Inventors: Todd P. Lary, Robert C. Burr, Christopher W. Snow
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Patent number: 7157274Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: September 16, 2003Date of Patent: January 2, 2007Assignee: Cytonome, Inc.Inventors: Sebastian Böhm, John R. Gilbert, Manish Deshpande
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Patent number: 7104405Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: September 13, 2004Date of Patent: September 12, 2006Assignee: Cytonome, Inc.Inventors: Sebastian Böhm, John R. Gilbert, Manish Deshpande
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Patent number: 6976590Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: December 23, 2002Date of Patent: December 20, 2005Assignee: Cytonome, Inc.Inventors: Manish Deshpande, John Gilbert
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Patent number: 6822180Abstract: A microchip comprises a flow pass in which a solution containing particles can flow, and a deflection mechanism for deflecting a portion of the particles as the particles flow through the flow pass.Type: GrantFiled: December 6, 2001Date of Patent: November 23, 2004Assignee: Minolta Co., Ltd.Inventors: Yasuhisa Fujii, Yusuhiro Sando
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Patent number: 6808075Abstract: A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.Type: GrantFiled: June 24, 2002Date of Patent: October 26, 2004Assignee: Cytonome, Inc.Inventors: Sebastian Böhm, John R. Gilbert, Manish Deshpande
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Patent number: 6659284Abstract: A process, a means of transferring mineable material from any number of sources to a number of devices capable of separating out values from that mineable material. See (FIG. 1) the mineable material enters the hose (1), the hose (1) being under vacuum, and is transferred in a flow of air to the upper portion of a hopper (2). The hopper (2) is also under vacuum. The flow of air leaves the upper portion of the hopper (2) through hose (4), which is connected, to a vacuum blower (5). The mineable material, being heavier than air is deposited in the hopper (2). The mineable material is removed from the bottom of the hopper (2) by means of a variable speed drive screw conveyor (3) and is transferred to a separation device (8). The level of heavy mineable material (6) contained in the hopper (2), along with the mineable material contained in the screw conveyor (3) causes a seal against the force of vacuum and allows the mineable material to enter and be removed from hopper (2) simultaneously if desired.Type: GrantFiled: March 4, 2002Date of Patent: December 9, 2003Inventor: H. Glenn McCray
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Patent number: 6646218Abstract: An article sorting apparatus and method is disclosed and which conveys a mixture of articles on a conveyor belt and through an inspection zone, and which includes at least one illumination source emitting red, green, and infrared radiation for illuminating the articles in the inspection zone; a detector system for sensing the red, green, and infrared radiation reflected from the articles in the inspection zone, and which generates red data, green data, and infrared data; a processor receiving the red data, green data, and infrared data and which generates article sorting data; and a sorter responsive to the sorting data for separating the articles into acceptable articles and unacceptable articles.Type: GrantFiled: December 18, 2001Date of Patent: November 11, 2003Assignee: Key Technology, Inc.Inventors: Duncan Campbell, Todd Hoffman, Cliff Leidecker, H. Parks Squyres
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Patent number: 6634834Abstract: A process and apparatus for effecting the transportation of sulfur pellets with the recovery of sulfur fines is disclosed. This is accomplished by a combination of steps and apparatus which include pumping water from a water supply into solid sulfur pellets with a jet-venturi/eductor pumping system to produce a sulfur water slurry containing sulfur pellets and sulfur fines, pumping the sulfur water slurry with one or more rotating disk/boundary layer pumps to a series of static screens to remove large lumps and impurities, a sulfur fines slurry, and a washed sulfur pellet slurry, contacting the sulfur pellet slurry with a dewatering disk to remove substantially all the remaining water, transporting the dewatered sulfur pellets to storage, pumping the sulfur fines slurry to a hydrocyclone to separate all the water from the sulfur fines, recycling the recovered water to said water supply following the addition of an alkaline neutralizing agent when needed, and recovering the sulfur fines.Type: GrantFiled: April 2, 2002Date of Patent: October 21, 2003Inventor: Gerard E. d'Aquin
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Patent number: 6527125Abstract: A system for delivering the same or differing controllable amounts of washing liquid to several flights of a spiral separator including a housing, a plurality of spaced members having a respective generally vertical passage communicating with fluid in the housing and permitting fluid to flow therethrough. A plurality of fluid passageways respectively communicate with the members to provide the same or differing amounts of liquid to each of the flights. The distributor housing may include a central liquid receiving chamber, a plurality of spaced compartments located in proximity with the chamber, a plurality of passages throughwhich fluid flows into fluid passageways respectively coupled to the compartments, a single flow controller rotatable therein to expose different portions of said passages at every rotation thereby varying the liquid flow to each compartment.Type: GrantFiled: June 15, 2001Date of Patent: March 4, 2003Assignee: Outokumpu OyjInventor: Timo U. Niitti
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Patent number: 6482652Abstract: An automated particle sorter having a fluid flow path, which places single biological particles in an optical cuvette. An exciting light irradiation system having a light source emits a source of light through the cuvette. The light excites a fluorescent substance present on the particle, and the emitted light is detected by a light detection apparatus containing at least two detection elements for measuring the fluorescence emitted from the fluorescent substance. A light separation element separates the fluorescence from the exciting light. A data processor compares the signal received from the fluorescent light; and from the background autofluorescent signal, and according to pre-set parameters, controls the position of a collection conduit between two set points. The first being a collection set point for the collection of objects having a first phenotype and the second being a set point for the collection of objects having a second phenotype.Type: GrantFiled: March 21, 2001Date of Patent: November 19, 2002Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Eileen Furlong, David Profitt, Matthew Scott
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Patent number: 6372506Abstract: An apparatus and method for verifying the drop delay in a flow cytometer, which is indicative of the time that elapses from a moment at which a particle of interest is detected at an interrogation point in the flow of cytometer to the moment at which a sorting condition, such as a charging potential, is applied in response to the detection to a droplet forming at a droplet forming location in the flow cytometer. The apparatus and method analyzes the content of the droplets formed by the flow cytometer, and based on the analysis, provides an indication as to whether the drop delay time at which the flow cytometer is operating is correct. Specifically, the charging potential should be applied to the droplet containing the detected particle of interest. The content of the droplets can be analyzed at the droplet formation point, or at a location downstream of the droplet formation point, to detect the presence or absence of a particle of interest that was detected at the interrogation point in the flow cytometer.Type: GrantFiled: July 2, 1999Date of Patent: April 16, 2002Assignee: Becton, Dickinson and CompanyInventor: Pierce Owen Norton
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Patent number: 6163000Abstract: An inspecting sorting machine for finished products of plastic film capacitor, includes a pneumatic pump, an automatic feeding table, a main inspecting machine, a central processing unit, a number of measuring gauges, a charging and discharging power supply and a motor transmission mechanism,the pneumatic pump is used with several pneumatic cylinders for a number of material-falling stations of the main inspecting machine to force capacitors to fall down,the automatic feeding table has at least two electromagnetic vibration type automatic feeding plates so that capacitors which are to be inspected are transported to a linear feeding unit of the inspecting main machine;the main inspecting machine includes a feeding plate with four claws, a main testing plate, a fixture plate, a full foot mechanism, a predicting mechanism, an insulation impedance testing point and a high low frequency capacity consumption testing mechanism which are all driven by the motor transmission mechanism which is mounted behind the inspType: GrantFiled: April 19, 1999Date of Patent: December 19, 2000Inventor: Robert S. Huang
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Patent number: 6015049Abstract: An apparatus for the grading of fish into various size categories, utilizing a series of panels with progressively smaller spaces between grading bars on the panels. The panels are attached to a panel box that may be raised or lowered within a holding vat. Water constantly flows through the holding vat, up through the panel box, and out over a spillway at the top front of the holding vat. By raising the panel box, the largest fish are forced out of the holding vat and down the spillway by the grading bars on the panels inside the panel box. Smaller fish swim through the grading bars on the panels with wider spaces between grading bars, and are not forced out of the holding vat until a lower panel with narrower spaces between grading bars is raised to the edge of the spillway. The constant flow of water up and toward the spillway causes the fish to instinctively swim downward and align themselves parallel to the grading bars and keeps the fish oxygenated during the grading process.Type: GrantFiled: August 31, 1998Date of Patent: January 18, 2000Assignee: The Board of Trustees of the University of ArkansasInventor: David L. Heikes
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Patent number: 5998212Abstract: This invention relates to a method and apparatus for flexibly controlling sorting decisions for a flow cytometer or similar instrument at a purity vs. yield ratio of sorted particles, particularly at high event rates. The system monitors distances between sequential objects to determine if they are in close enough proximity to be within a single resolution unit of the sorting device. The "friend" or "foe" status of neighboring events is considered by this system in dealing with detected "coincident" events. The system operates on information of the desirability to sort the object, i.e. droplet, based upon the properties of the individual object. A storage and retrieval method is provided for making the information available at the time a sort operation based on a sorting logic condition is performed. Accordingly, an easily reconfigurable mode of operation control is provided to allow customized sorting strategies, based on the needs of individual applications or experiments.Type: GrantFiled: August 26, 1996Date of Patent: December 7, 1999Assignee: University of Texas Medical Branch at GalvestonInventors: Mark A. Corio, James F. Leary
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Patent number: 5916449Abstract: A method and an arrangement by which separating liquid streams, such as occur for example in cell sorters, are monitored automatically. An image of the separating liquid streams is recorded and the position of a separation point at which the drops separate from a column of liquid is found using image analysis methods. Various solution possibilities are indicated for the suitable preparation of the image information for easier processing.Type: GrantFiled: December 3, 1996Date of Patent: June 29, 1999Assignee: Siemens AktiengesellschaftInventors: Joachim Ellwart, Ingolf Karls
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Patent number: 5909813Abstract: A force field separator which can utilize either electric or magnetic fields to separate materials which are sensitive to those forces. As an electrostatic precipitator it produces higher separation efficiencies with smaller equipment and lower cost. As a magnetic separator it separates paramagnetic and diamagnetic materials with lower strength fields. It employs small sectional area rods which generate high field gradients between adjacent rods which are oriented at an angle to the flow direction inside an elongate housing which contains the fluid stream. The separation forces are a resultant of the force propelling the fluid through the housing and the field forces produced by the field gradients. The resultant force direction is towards multiple openings along the outside length of the housing where a separate plenum flow of separated materials is created.Type: GrantFiled: January 13, 1997Date of Patent: June 8, 1999Assignee: Lift Feeder Inc.Inventor: Ceil Stelzer
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Patent number: 5837200Abstract: The sorting device is able to sort biological objects, particularly cells or viruses, in liquids as a function of physically measurable criteria or properties. The sorting apparatus is provided with a feed inlet (1) for the biological liquid which branches into a microstructured system of multi-parallel main channels (3) and sorting modules (4) each with a switch unit for distribution to two different outlet channels (19,20). Inside a sorting module (4), at least one sensor (9,10) is arranged on each main channel, and a sorting actuator (12) controlled by the relevant sensor is arranged on each switch unit (11). Finally, each outlet channel (20) is connected to a collecting channel (6) for the unselected biological cells or viruses, and each outlet channel (19) is connected to a collecting channel (5) for the selected cells or viruses. If the cells or viruses are magnetically marked, it is possible to dispense with the sensor (9,10) on the main channels (3).Type: GrantFiled: May 24, 1996Date of Patent: November 17, 1998Assignee: Bayer AktiengesellschaftInventors: Edgar Diessel, Walter Weichel
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Patent number: 5804143Abstract: A system for sorting particles is arranged such that the presence or absence of multiple parameters is determined for each particle in a flow of particles, and a logic condition is determined based on the multiple parameters. Thereafter, particles are outputted from the system when the logic condition is present. Accordingly, multiparameter high-speed measurements of a rare subpopulation of particles (e.g. biological cells) can be made amidst a larger population of particles with differing characteristics. When attached to a multiparameter flow cytometer/cell sorter and microcomputer, the system allows multiparameter analysis of cells at rates in excess of 100,000 cells/sec. This system can be an outboard module attached to a commercially available or home-built flow cytometer.Type: GrantFiled: August 23, 1996Date of Patent: September 8, 1998Assignee: University of Texas Medical Branch at GalvestonInventors: James F. Leary, Mark A. Corio, Scott R. McLaughlin
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Patent number: 5695070Abstract: A unit for sampling and quality controlling tobacco items, in particular cigarettes, wherein a sample item, fed by a first conveyor along a first given path, is transferred automatically by a selectively operated spoon-shaped diverter along a second path to a second conveyor tangent to the first path. The sample item is fed to a support in which it is supported in facing relation to an optical control device. The sample item is inspected in the support and the optical control device emits signals as a function of the surface characteristics of the sample item.Type: GrantFiled: May 10, 1995Date of Patent: December 9, 1997Assignee: G.D Societa' Per AzioniInventor: Fiorenzo Draghetti
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Patent number: 5667080Abstract: A hand-held jeweler's vacuum comprises an elongated vacuum member with an opening at one end, motor drive means located at the other end and an aperture in the bottom of the elongated member. A detachable box member is mounted beneath the aperture to receive stones and metal pieces. Internally, a mesh filter and a vacuum filter are positioned in the intake path at approximately a 45 degree angle to the air flow and a pre-determined distance apart. In operation, the vacuum picks up metal and stones which are stopped by the mesh filter and the vacuum filter from proceeding through the vacuum filter and the stones and metals fall into the box. The stones and metals can the be removed while other particles are collected in the storage space beyond the filters. The invention permits the salvage of small stones and precious metals which otherwise would be lost during the manufacturing process.Type: GrantFiled: July 17, 1995Date of Patent: September 16, 1997Inventor: Stanley Klein
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Patent number: 5550058Abstract: This invention relates to a method and apparatus for flexibly controlling sorting decisions for a flow cytometer or similar instrument at a purity vs. yield ratio of sorted particles, particularly at high event rates. The system monitors distances between sequential objects to determine if they are in close enough proximity to be within a single resolution unit of the sorting device. The "friend" or "foe" status of neighboring events is considered by this system in dealing with detected "coincident" events. The system operates on information of the desirability to sort the object, i.e. droplet, based upon the properties of the individual object. A storage and retrieval method is provided for making the information available at the time a sort operation based on a sorting logic condition is performed. Accordingly, an easily reconfigurable mode of operation control is provided to allow customized sorting strategies, based on the needs of individual applications or experiments.Type: GrantFiled: December 15, 1992Date of Patent: August 27, 1996Assignee: University of RochesterInventors: Mark A. Corio, James F. Leary
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Patent number: 5382370Abstract: A process for continuously separating relatively coarse particles from a suspension of a mixture of particles in a liquid wherein the suspension is caused to pass through a screening medium which is rotating in its own plane so that the coarse particles are retained on the surface of the screening medium; characterized in that atmospheric pressure above the screening medium is caused to be in excess of the pressure below that medium.Type: GrantFiled: April 7, 1993Date of Patent: January 17, 1995Assignee: ECC International Ltd.Inventors: Thomas R. Jones, Reginald L. Phillips, Hugh R. Falcon-Steward
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Patent number: 5273162Abstract: A method and apparatus for separating high density materials from less dense materials suspended in a fluid within a conduit. A pump generates carrier fluid motion which is fed through the conduit. Solids from a placer deposit are mixed with the carrier fluid and induced through a suction hose, then into two positively sloped separating chambers that are arranged in tandem in the conduit. The first separating chamber is cylindrical in shape, and motion of the fluid through the chamber is linear. The second separating chamber's cross section shape is rectangular, with a parabolic flow path. The second stage separator floor is variably banked, with the angle of bank and curvature increasing toward the discharge end. Solids, that are mixed with the carrier fluid, are forced along the flow path by dynamic drag of the fluid. Less dense solids travel up the positive slope at a greater velocity than more dense solids. The larger and slower moving dense solids are trapped in two sumps in the first chamber.Type: GrantFiled: September 25, 1992Date of Patent: December 28, 1993Assignee: GAPC CorporationInventor: James W. Riherd
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Patent number: 5199576Abstract: This invention relates to a method and apparatus for flexibly controlling sorting decisions for a flow cytometer or similar instrument at a purity vs. yield ratio of sorted particles, particularly at high event rates. The system monitors distances between sequential objects to determine if they are in close enough proximity to be within a single resolution unit of the sorting device. The "friend" or "foe" status of neighboring events is considered by this system in dealing with detected "coincident" events. The system operates on information of the desirability to sort the object, i.e. droplet, based upon the properties of the individual object. A storage and retrieval method is provided for making the information available at the time a sort operation based on a sorting logic condition is performed. Accordingly, an easily reconfigurable mode of operation control is provided to allow customized sorting strategies, based on the needs of individual applications or experiments.Type: GrantFiled: April 5, 1991Date of Patent: April 6, 1993Assignee: University of RochesterInventors: Mark A. Corio, James F. Leary
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Patent number: 5180065Abstract: This invention measures the properties of individual particles in particle-suspended liquid by an optical technique or the like, causes the particle-suspended liquid to fall while separating the liquid into droplets containing the individual particles therein, and causes liquid droplets discharged from a nozzle to collide with the droplets from a direction differing from the direction of fall, in conformity with the properties of the particles discriminated by the measurement, so as to change the direction of fall of the falling droplets, thereby fractionating the particles.Type: GrantFiled: October 11, 1990Date of Patent: January 19, 1993Assignee: Canon Kabushiki KaishaInventors: Yoshiyuki Touge, Yoshito Yoneyama
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Patent number: 5143224Abstract: A method for separating diamonds from associated gangue in a diamondiferous material. The method comprises the steps of mixing the diamondiferous material with water to form a slurry and passing the slurry through laser radiation of known wavelength in the infra red part of the electromagnetic spectrum to cause Raman spectral scattering of the radiation from the slurry. The scattered radiation is collected and filtered to isolate diamond-relevant radiation and the filtered radiation is analyzed to determine whether it is indicative of the presence of diamond. Finally, on the basis of such analysis, high diamond content slurry is separated from low diamond content slurry.Type: GrantFiled: March 11, 1991Date of Patent: September 1, 1992Assignee: Turret Holdings LimitedInventor: Steven P. Burchell
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Patent number: 5101978Abstract: A fluidic sorting device for the separation of two or more visually diffet materials or materials which react differently to an externally applied force. These materials are suspended in a fluid. The device comprises a fluidic logic element to which a machine vision apparatus is connected. The machine vision apparatus may be programmed to identify specific particulate materials. The machine vision apparatus captures an image of a particle or material, interprets the image, then makes subsequent value judgements, and decides as to whether the particle is to be separated out. The decision of the machine vision apparatus controls a fluidic logic element which facilitates the separation of the particles or materials. The machine vision apparatus may, optionally, comprise a counter. The novelty of the invention lies with the combination of fluidics with a machine vision apparatus.Type: GrantFiled: November 27, 1989Date of Patent: April 7, 1992Assignee: The United States of America as represented by the Secretary of the ArmyInventor: Ira A. Marcus
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Patent number: 5034122Abstract: A bar grid is formed with multiple vertical rods supporting multiple horizontal roll formed elements with a flange at a front edge of each element. The grid is mounted in a water effluent stream on each side of a solid filter screen or grinder and funnels solid material down to the compactor without buildup of solids on the grid screen.Type: GrantFiled: July 20, 1990Date of Patent: July 23, 1991Assignee: Wiesemann Enterprises, Inc.Inventor: Bruce O. Wiesemann
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Patent number: 4981580Abstract: A coincidence arbitration system for a sorting cytomteter which detects and sorts particles using a flow chamber and a stream of droplets. Those droplets containing selected particles are sorted by selectively applying a charge thereto and passing the droplets through deflection plates. After detection, the particle data is delayed and analyzed to make sort decisions. The delay is for a period of one and one fourth droplet time periods less than the time the particle is formed into a droplet. At the time the command is issued creating the charge on the droplet to be formed, the coincidence arbitration circuit looks four quarter droplet times ahead and behind of the event to determine whether a coincidence is occurring, and if so, whether the coincidence is with a similar type of particle or a different type of particle. Based on this information, appropriated sort or no-sort commands are issued.Type: GrantFiled: May 1, 1989Date of Patent: January 1, 1991Assignee: Coulter CorporationInventor: Robert E. Auer
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Patent number: 4976356Abstract: A method of optically checking the appearances of chips and sorting the chips comprises the steps of feeding chips onto chip-passage body to cause the chips to run on the chip-passage body in a predetermined direction; during the running of the chips on the chip-passage body, individually separating the chips to stop the chips one by one at each of two predetermined checking positions; irradiating light obliquely and straightly with respect to a chip at one of the predetermined checking positions to pick up an optical image of one of undersurface and top surface sides of the chip as a video signal by means of a first TV camera; irradiating light obliquely and straightly with respect to the chip at the other of the predetermined checking positions to pick up an optical image of the other of the undersurface and top surface sides of the chip as a video signal by means of a second TV camera; sending the video signals to image processing sections, each of which includes at least an analog-to-digital conversion unType: GrantFiled: February 28, 1989Date of Patent: December 11, 1990Assignee: TDK CorporationInventors: Touru Mizuno, Yasuhiko Kitajima
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Patent number: 4936465Abstract: A method and apparatus for controlling flows of fluids, suspensions, gases, aerosols, and for sorting individual particles, flowing in transporter ducts of a flow-through duct system, using for control of the flow and hence, for dispensing and sorting processes, a pressure increase for a short time interval, at the entrances of preselected ducts having a value so that the flow of the fluid or gas to be dispensed comes to a stop at these entrances and is thus constrained together with the particle to flow into ducts where the pressure increase does not take place during the same dispensing/sorting phase. The momentary pressure increase is caused at the ducts either by injection of another fluid or gas through the injection duct, corresponding to these ducts, or by generation of a gas bubble or vapor between electrodes situated at the entrance of these ducts.Type: GrantFiled: September 15, 1989Date of Patent: June 26, 1990Inventor: Tibor Zold
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Patent number: 4859120Abstract: A pneumatic conveying system for conveying articles to be conveyed, which are successively discharged from an assembling machine, to a plurality of conveying positions. In this pneumatic conveying system, pneumatic conveying and conveyor conveying are combinedly used, whereby conveying for a relatively long distance is effected by pneumatic conveying low in cost per unit conveying distance, and conveying for distributing the articles to be conveyed to the plurality of conveying positions is effected by conveyor conveying easy in distributing. Furthermore, transfer from the pneumatic conveying of the articles to be conveyed to the conveyor conveying is made smooth, and flaw control measure and blocking preventive measure for the articles to be conveyed are applied.Type: GrantFiled: January 15, 1988Date of Patent: August 22, 1989Assignee: Fuji Photo Film Co., Ltd.Inventors: Yukihiro Tsubata, Masaru Shiino
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Patent number: 4849999Abstract: The invention includes an apparatus for and method of moving textile articles such as pieces of laundry or the like comprising an enclosed passageway having two opposing open ends, and at least one bend between the two open ends; a vacuum source coupled with one of the two open ends and developing a subatmospheric pressure along the passageway and at the other open end of the passageway to draw textile articles into the other open end and through the passageway to the one open end; and a sensor located at the one bend and sensing textile articles drawn through the passageway. The sensor is coupled with an appropriate counter for accumulating a count of successive textile articles drawn through the passageway. A delay circuit is included between the sensor and the accumulator to inhibit successive detector outputs for a selectable but fixed time period, regardless of the size of the textile articles being passed and counted.Type: GrantFiled: August 31, 1987Date of Patent: July 18, 1989Assignee: Markman and AssociatesInventors: Jerry W. Humphreys, Michael S. Radler
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Patent number: 4823396Abstract: A device is provided for automatically inspecting a fastener for defects prior to its installation in an assembly operation. The fastener is propelled by air or gravity along a feed line. The inspection device is connected in the feed line and has a cam member that is positionable into the fastener's path of travel for blocking it at a certain position. A television camera produces a video image of the stopped fastener, which shows the fastener's actual dimensions. A computer then compares the actual dimensions with the fastener's desired, which are prestored in the computer's memory. If the two substantially match, the fastener is known to be acceptable for installation.Type: GrantFiled: July 21, 1987Date of Patent: April 18, 1989Assignee: The Boeing CompanyInventor: Douglas Thompson