Proportionate Feed Means Patents (Class 210/101)
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Patent number: 9695074Abstract: A device for generating high pressure ozone water by using a low pressure ozone gas source includes an ozone gas and water mixture bucket. A water inlet of the ozone gas and water mixture bucket is connected with a tap water inlet through a pipe system and a water inlet solenoid valve. A water outlet of the ozone gas and water mixture bucket is connected with a water outlet through the pipe system and a water outlet one-way valve. An ozone gas inlet of the ozone gas and water mixture bucket is connected with an ozone inlet through the pipe system and an ozone gas inlet one-way valve. The ozone gas and water mixture bucket is provided with an off-gas outlet. The off-gas outlet is connected with a discharge outlet through the off-gas destruct bucket. The water inlet solenoid valve is connected with a power control unit.Type: GrantFiled: August 4, 2015Date of Patent: July 4, 2017Assignee: BIOTEK ENVIRONMENTAL SCIENCE LTD.Inventor: Mingyung Hsu
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Patent number: 9682182Abstract: Provided is a dialysate supply unit and a blood dialyzing apparatus including the dialysate supply unit for supplying dialysate of a dialysate tank to a hemodialyzer and collecting dialysate passing through the hemodialyzer in an effluent tank. The dialysate supply unit includes a dialysate pump, an effluent pump, a first flow-blocking valve, a second flow-blocking valve, and a flow-blocking valve driver. The dialysate pump connects the dialysate tank and the hemodialyzer and the effluent pump connects the hemodialyzer and the effluent tank. The first flow-blocking valve alternately blocks a dialysate outflow tube connecting the hemodialyzer and the dialysate pump and an effluent inflow tube connecting the hemodialyzer and the effluent pump. The second flow-blocking valve alternately blocks a dialysate inflow tube connecting the dialysate pump and the dialysate tank and an effluent outflow tube connecting the effluent pump and the effluent tank. The flow-blocking valve driver drives the flow-blocking valve.Type: GrantFiled: April 3, 2014Date of Patent: June 20, 2017Inventor: Taebeom Cho
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Patent number: 9649419Abstract: A portable hemodialysis system is provided including a disposable cartridge and a reused dialysis machine. The disposable cartridge includes a dialysate flow path and a blood flow path which flow in opposite directions through a dialyzer. The disposable cartridge includes a filter for removing waste products from the dialysate. The reused dialysis machine possesses a reservoir for dialysate, various sensors including a reservoir level sensor assembly, and a processor connected to the various sensors for controlling and monitoring hemodialysis treatment. The reservoir level sensor assembly includes a vertically extending electrode array for transmitting electrical signals to the processor detecting whether the reservoir possesses sufficient dialysate for therapy, and for detecting whether there is a fault condition during therapy such as a loss of dialysate in the reservoir or an increase in fluid in the reservoir which may indicate a failure in the dialysis membrane.Type: GrantFiled: June 29, 2015Date of Patent: May 16, 2017Assignee: EASYDIAL, INC.Inventors: Renato Giordano, Rodney Corder
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Patent number: 9643103Abstract: A method of preparing a liquid mixture for use in a liquid chromatography system is provided. The mixture comprises one or more acids, one or more bases, one or more salts, and one or more solvents, and the method comprises the steps of: i) calculating pH and/or salt concentration at a particular time t from a user-determined gradient function; and ii) based on the values obtained in step (i), calculating percent acid, percent base, percent salt and percent solvent in the liquid mixture at time t. A liquid chromatography system incorporating such method is also provided.Type: GrantFiled: May 24, 2011Date of Patent: May 9, 2017Assignee: Waters Technologies CorporationInventors: Richard W. Andrews, John Heden, Michael Jackson, John Lamoureux, Guo-Zhong Li, Barry Sunray, Thomas E. Wheat
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Patent number: 9631618Abstract: A device for determining a leakage of fluid in a piston pump, wherein the piston pump comprises a piston arranged in such a manner that it can reciprocate in a piston chamber for delivering fluid, wherein the device comprises a control unit for controlling the piston in such a manner that the piston executes two piston chamber evacuation processes with different evacuation times, in each case for at least partial evacuating of fluid located in the piston chamber, and a determination unit for determining the leakage based on a comparison of fluid quantities evacuated from the piston chamber in the two piston chamber evacuation processes.Type: GrantFiled: April 2, 2015Date of Patent: April 25, 2017Assignee: Agilent Technologies, Inc.Inventors: Konstantin Shoykhet, Klaus Witt
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Patent number: 9618485Abstract: In a high performance liquid chromatography system, wherein a mobile phase is driven through a stationary phase for separating compounds of a sample fluid comprised in the mobile phase, a flow rate of the mobile phase is controlled in dependence on a variation in a control value in the system.Type: GrantFiled: November 12, 2007Date of Patent: April 11, 2017Assignee: Agilent Technology, Inc.Inventor: Klaus Witt
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Patent number: 9580677Abstract: Provided are an apparatus for filtering a fluid, the apparatus including a first flow channel and a second flow channel which are connected to each other in a fluid communicable manner via a filtration medium, and a method of isolating particles using the apparatus.Type: GrantFiled: February 4, 2014Date of Patent: February 28, 2017Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Hun-joo Lee, Jong-myeon Park
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Patent number: 9475714Abstract: A method of treating wastewater in a wastewater treatment system is disclosed. The wastewater treatment system receives an influent of the wastewater and having at least a first bioreactor and a second bioreactor each having therein bacteria for treating the waste material. The method comprises: monitoring a load parameter being indicative of a load on the second bioreactor; responsively to a monitored value of the load parameter, controlling at least one flow rate selected from the group consisting of (i) a flow rate from the influent to the second bioreactor through the first bioreactor, and (ii) a flow rate from the influent directly to the second bioreactor, so as to maintain a generally constant and predetermined load on the second bioreactor.Type: GrantFiled: July 4, 2012Date of Patent: October 25, 2016Assignee: Biological Petroleum Cleaning Ltd.Inventors: David Amir, Amir Kleinstern, Gili Bittan-Banin
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Patent number: 9434626Abstract: A water conditioning system that both softens and improves the smell of water by removing dissolved ferrous iron and hydrogen sulfide from the water includes: a water softening tank, a cation exchange media situated in the water softening tank, a brine tank, a programmable control valve which regulates flow through the system and the periodic rejuvenation of the cation exchange media using flow from the brine tank, a valve that assists in providing a flow of aerated, pressurized water to the system, and an adapter with a bottom portion and a flow control valve that control the volume of the gaseous pocket that is created in the top portion of the water softening tank.Type: GrantFiled: September 22, 2012Date of Patent: September 6, 2016Inventor: Scott R. Handy
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Patent number: 9393504Abstract: A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate and precise flow delivery at capillary (<0.1 mL/min) and nano-scale (<1 ?L/min) HPLC flow rates.Type: GrantFiled: January 22, 2014Date of Patent: July 19, 2016Assignee: Waters Technologies CorporationInventors: Geoff C. Gerhardt, Joseph A. Luongo
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Patent number: 9360006Abstract: A method for controlling operation of a pump unit, where the pump unit includes a primary piston pump having a primary piston and a secondary piston pump having a secondary piston. The primary piston pump is fluidically connected with the secondary piston pump. The primary piston pump includes an inlet valve and an outlet valve, and the pump unit operates periodically according to a pump cycle. The method includes determining a fluid pressure of fluid dispensed by the pump unit, and performing a closed loop control of a position of the primary piston in dependence on the fluid pressure of the fluid dispensed by the pump unit during a first time interval of the pump cycle.Type: GrantFiled: May 4, 2012Date of Patent: June 7, 2016Assignee: Agilent Technologies, Inc.Inventors: Philip Herzog, Konstantin Choikhet, Klaus Witt, Herbert Anderer
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Patent number: 9243629Abstract: A pump for use in high pressure liquid chromatography includes a housing with a pump head at one end and an axially-movable, high-pressure piston with a small-diameter plunger reciprocating within the pump head to move fluid from an inlet through an outlet at high pressure. An attached motor rotates a circular cam fixed off center on the motor shaft to reciprocate the piston that has an inner end in engaging contact with the cam periphery. An axially-aligned, torque-compensating piston is provided and has an inner end biased by spring force against the cam opposite the high-pressure piston. A large-diameter piston head may be fixed to the outer end of the torque-compensating piston and slidably mounted within a cylinder defined at the housing end opposite the pump head. The outer end of the piston head is open to ambient atmosphere.Type: GrantFiled: March 15, 2013Date of Patent: January 26, 2016Assignee: SIELC Technologies CorporationInventor: Yury Zelechonok
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Patent number: 9138693Abstract: The present invention relates to an automated solution preparation apparatus having containers for holding solid reagents, a dispensing mechanism for dispensing the reagents to a balance, a supply for providing liquid to rinse the reagents from the balance into a chamber where additional liquids can be added, and a manifold connected to the chamber for dispensing the solution into receptacles. The chamber can have probes for monitoring properties of the solution, and heating and cooling jackets for adjusting the solution temperature. The present invention also relates to a method for using the automated solution preparation apparatus to prepare solutions of different concentrations and properties by dispensing reagents from containers into a weighing zone, where each reagent is separately weighed and rinsed from the weighing zone into a chamber, diluting the reagents with additional liquid solvent to prepare the solution and discharging the solution from the chamber into receptacles.Type: GrantFiled: March 21, 2012Date of Patent: September 22, 2015Inventor: Salah M. Aouad
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Patent number: 9034179Abstract: A method and device for the cleaning of spiral wound membranes. In the device two or more spiral wound membranes are included in series in pressure tubes. The membranes are cleaned by longitudinal rinsing with water, in which a well-dissolvable gas has been dissolved. In the device for the purification of an aqueous fluid with spiral wound membranes, the membranes can be longitudinal rinsed with water, in which a well-dissolvable gas has been dissolved. As gas that is well-dissolvable preferably CO2 gas or a mixture of gasses is used.Type: GrantFiled: February 10, 2010Date of Patent: May 19, 2015Assignees: WE CONSULT VIANEN B.V., VITENS N.V.Inventors: Leo Peter Wessels, Walterus Gijsbertus Joseph Van Der Meer
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Patent number: 8992778Abstract: Embodiments of the present invention feature methods and apparatus for performing chromatographic separations. The invention feature methods and control means in the form of computer programs and software that control the formation of a concentration gradient at two or more total flow rates, with an elution period occurring in a slow flow rate and at least other portions of the gradient occurring during a fast total flow rate.Type: GrantFiled: February 5, 2007Date of Patent: March 31, 2015Assignee: Waters Technologies CorporationInventor: Hongji Liu
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Patent number: 8961783Abstract: A method of liquid chromatography includes providing one or more solvent reservoirs, providing a solvent pump, drawing one or more solvents into the pump in response to a pressure drop that promotes outgassing of the solvents, and dispersing outgassed bubbles into smaller bubbles to promote re-dissolution of the gas. A liquid-chromatography apparatus includes at least two solvent reservoirs, a pump, at least one bubble-dispersing unit that receives a pressurized flow of proportioned solvents from the pump, and a control unit. The control unit includes a processor and a memory that stores instructions; the control unit controls proportioning of solvents to obtain a preselected solvent composition, and pumping at flow rates to support preparative-scale or process-scale liquid chromatography.Type: GrantFiled: September 8, 2009Date of Patent: February 24, 2015Assignee: Waters Technologies CorporationInventors: Joshua A. Shreve, Michael R. Jackson
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Publication number: 20150034536Abstract: An apparatus for extracorporeal treatment of fluid and a process of setting up a medical apparatus for the delivery or collection of fluids are disclosed. According to the apparatus and the process, a control unit (10) is configured calculate set values of two or more of the fluid flow rates by imposing that an emptying time of containers of fresh fluid (16, 20, 21, 26) and/or a filling time of a waste container is substantially same as, or multiple of the emptying time of one or more of the other containers of fresh fluid.Type: ApplicationFiled: August 22, 2012Publication date: February 5, 2015Applicant: GAMBRO LUNDIA ABInventors: Hiram Rada, Dominique Pouchoulin, Georges Vantard, Alain Frugier
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Publication number: 20150034537Abstract: This invention is for an automatic drinking water enhancement apparatus consisting of a storage reservoir for water enhancement liquid connected to a positive displacement pump that will pump said water enhancement liquid proportional to the drinking water supply flow rate, and a merging and mixing means to combine the two streams, and an output leading to the dispenser to the user. The positive displacement pump may be powered by the drinking water stream flow and pressure, or by an electric motor with suitable electronic or computerized controls and sensors to drive the motor and infusion pump speed proportional to the filtered water flow rate, or as otherwise controlled. Fixed and variable control of the water enhancement liquid concentration in the output drinking water stream are included.Type: ApplicationFiled: July 30, 2013Publication date: February 5, 2015Inventor: David Warren Parish, SR.
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Patent number: 8932460Abstract: The present invention aims at providing a preparative separation/purification system for vaporizing an eluate in a short period of time, while enhancing the efficiency of collecting the target substance by accelerating the initiation of collecting the eluate.Type: GrantFiled: February 10, 2011Date of Patent: January 13, 2015Assignee: Shimadzu CorporationInventors: Tomoyuki Yamazaki, Przemyslaw Stasica, Bob Boughtflower
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Patent number: 8894848Abstract: The present invention relates to a water-filter device. This is distinguished by the provision of an adjusting medium (5) of which the volume and/or the structure change/changes by way of a liquid (6) which is in contact with the adjusting mechanism (1) and/or has flowed through the adjusting mechanism (1).Type: GrantFiled: December 21, 2007Date of Patent: November 25, 2014Assignee: Aquis Wasser-Luft-Systeme GmbH, Lindau, Zweigniederlassung RebsteinInventor: Roland Scholz
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Patent number: 8883013Abstract: The present invention relates to a treatment installation of aqueous fluid, in particular to ensure elimination of organic micropollutants and natural organic matter, comprising a single reactor (10) for treatment of aqueous fluid by contact with a fluidized bed of coagulated and flocculated powdered activated carbon, operating in ascending flow, said reactor being equipped with injection means of new powdered activated carbon, coagulant and polymer, arranged to define three distinct operating zones in the reactor: a first arranged zone (A) at the base of the reactor to ensure intake and homogeneous distribution of the aqueous fluid pre-treated by contact with coagulant and polymer, a second zone, surmounting the first, constituted by the fluidized bed of coagulated and flocculated powdered activated carbon (B), and a third zone (C), arranged in the top part of the reactor for separation and recovery of the purified aqueous liquid.Type: GrantFiled: June 9, 2010Date of Patent: November 11, 2014Assignee: SaurInventor: Jean Perot
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Publication number: 20140319032Abstract: A compact and portable liquid concentrator and contaminant scrubber includes a gas inlet, a gas exit and a flow corridor connecting the gas inlet and the gas exit, wherein the flow corridor includes a narrowed portion that accelerates the gas through the flow corridor. A liquid inlet injects liquid into the gas stream at a point prior to the narrowed portion so that the gas-liquid mixture is thoroughly mixed within the flow corridor, causing a portion of the liquid to be evaporated. A demister or fluid scrubber downstream of the narrowed portion removes entrained liquid droplets from the gas stream and re-circulates the removed liquid to the liquid inlet through a re-circulating circuit. A reagent may be mixed with the liquid to react with contaminants in the liquid.Type: ApplicationFiled: July 7, 2014Publication date: October 30, 2014Applicant: Heartland Technology Partners LLCInventors: Bernard F. Duesel, JR., Michael J. Rutsch, Craig Clerkin
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Patent number: 8871088Abstract: The present invention provides a liquid delivery device for liquid chromatographs which, by performing liquid delivery at an accurate flow rate with limited pulsation, gives accurate results of analysis. The present invention, with a view to preventing erroneous operation due to errors in measurements at the time of judgment of completion of compression of liquid, establishes the judgment point before the pressure measured by a cylinder pressure detector agrees with the pressure measured by a discharge pressure detector and also calculates the point of completion of compression. Control in this manner prevents pressure fluctuation. It also calculates for control the point of completion of compression from the history of compression performed previously.Type: GrantFiled: November 3, 2010Date of Patent: October 28, 2014Assignee: Hitachi High-Technologies CorporationInventors: Hironori Kaji, Hiroyuki Wada, Masato Fukuda
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Patent number: 8852443Abstract: Various “no filter, no run” fuel filtration designs are described that include a variable restriction orifice (VRO) designed to vary the amount of fluid, for example fuel, that reaches a fluid outlet. The VRO has a fully open position at which a maximum non-zero fluid flow is permitted, and a fully closed position at which a limited amount of fluid can flow to the outlet. In the case of diesel fuel, the amount of fuel flow permitted at the fully closed position provides lubrication of downstream fuel system components, for example the fuel pump, but is insufficient to permit engine operation.Type: GrantFiled: September 12, 2007Date of Patent: October 7, 2014Assignee: Cummins Filtration IP, Inc.Inventors: Todd Forrest, J. Bruce Schelkopf, Ted S. Loftis, Barry Verdegan, Wassem Abdalla, Mark Wieczorek, Gérard Malgorn, Charles W. Hawkins, Chad Thomas, Joe Saxon, Mark Johnson, Naren Shaam
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Publication number: 20140224736Abstract: A method and a device are disclosed for controlling or regulating an ultrafiltration in a dialysis treatment in which blood to be ultrafiltered flows in an extracorporeal blood circulation (109) through a blood chamber (110) of a dialyzer (113), which is divided by a semipermeable membrane (111) into the blood chamber (110) and a dialysis fluid chamber (108), and dialysis fluid in a dialysis fluid circulation (109) flows through the dialysis fluid chamber (108) of the dialyzer (113). The device has a blood pump (115) for creating a blood flow in the extracorporeal blood circulation (112), a dialysis fluid pump (107) for creating a dialysis fluid flow in the dialysis fluid circulation (109), a balancing device (104) for setting up a fluid balance in the dialysis fluid circulation between an inflow (106) and an outflow (105) of the dialysis fluid chamber (113) as a measure of the ultrafiltration, and a regulating unit (101) for regulating the blood pump (115) and/or the dialysis fluid pump (107).Type: ApplicationFiled: February 12, 2014Publication date: August 14, 2014Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Alexander HEIDE, Dejan NIKOLIC, Arne PETERS, Christoph WIKTOR
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Publication number: 20140227134Abstract: The invention relates to an arrangement (10, 100) for removing carbon dioxide from an extracorporeal flow of blood and/or for oxygenating the extracorporeal flow of blood. The arrangement (10, 100) comprises an oxygenator (12), a first gas storage tank (24) in which a first gas is contained and at least a second gas storage tank (24) in which a second gas is contained. Further the device (10, 100) has a gas mixing unit for mixing a purge gas from the first and the second gas and an electronic control unit (30) for controlling the gas mixing unit (50). The control unit (30) comprises an input unit (40) by means of which the content of the first gas in the purge gas is adjustable by an operator, wherein the control unit (30) controls the gas mixing unit (50) such that the purge gas has the adjusted content of the first gas.Type: ApplicationFiled: July 27, 2012Publication date: August 14, 2014Applicant: Maquet Vertrieb und Service Deutschland GmbHInventors: Thilo Joost, Rainer Kobrich
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Publication number: 20140217029Abstract: A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD) that has a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the flow path.Type: ApplicationFiled: February 1, 2013Publication date: August 7, 2014Applicant: MEDTRONIC, INC.Inventors: Thomas E. Meyer, David B. Lura, Bryant J. Pudil, Martin T. Gerber
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Patent number: 8715510Abstract: An apparatus and methods for measuring the concentration of an additive are disclosed. The apparatus comprises a treatment stream (1) and a dosing stream (2). An additive is added to the dosing stream using a metering device (3). In some embodiments, the dosing stream is mixed after adding the additive using a first mixing device (4). Downstream from the metering device and the mixing device, the concentration of the additive in the dosing stream is measured using a monitor flow cell (5). In some embodiments, the dosing stream and treatment stream are combined (6) and mixed using a second mixing device (7). The concentration of the additive in the treatment stream can be calculated as a function of the volumetric flow rate ratio of the dosing stream to the treatment stream and the measured concentration of the additive in the dosing stream.Type: GrantFiled: December 14, 2011Date of Patent: May 6, 2014Assignee: Ferrate Treatment Technologies, LLCInventors: Luke J. Daly, Craig S. Alig
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Patent number: 8709241Abstract: A control unit for a softening device, comprising a primary inlet for untreated water, a primary outlet for blended water, a sensor for determining the water hardness of the untreated water WHraw, or the blended water WHblend, a secondary outlet, a secondary inlet, a bypass line, a blending means which can be automatically adjusted for mixing a blended water flow Vblend(t) from a first partial flow (V(t)part1soft of the secondary inlet and a second partial flow V(t)part2raw of the bypass line, and an electronic control means, wherein the control means is designed to readjust the adjustment position of the blending means by means of the determined water hardness in such a fashion that the water hardness in the blended water flow Vblend(t) is adjusted to a predetermined desired value, enables partial softening of water on the basis of fully automatic blending, thereby utilizing already existing softening devices.Type: GrantFiled: July 9, 2009Date of Patent: April 29, 2014Assignee: Judo Wasseraufbereitung GmbHInventors: Carsten Dopslaff, Ralf Soecknick, Klaus Neidhardt, Alexander Haug, Siegfried Melcher
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Patent number: 8696915Abstract: A method of treating water in order to minimize scaling and biomass buildup in water conduits or containers in which the treated water is used includes pressurizing and optionally filtering ambient air, processing the pressurized ambient air in a chamber including at least one ultraviolet light source operated to generate an output flow mixture of pressurized air and reactive oxygen species (ROS) gas, mixing the pressurized ROS/gas output mixture to realize a flow of water/pressurized ROS gas/air mixture and outputting the flow of water/pressurized ROS gas/air mixture as the treated water process product. The process includes generating reactive oxygen species (ROS) gas in the pressurized ROS/gas output mixture including at least one of Super Oxide (O2?), Peroxide (—O2—), Hydro peroxide (HO2?), Hydroxyl Radicals (OH.), Ozone (O3?) and Molecular Oxygen (O2).Type: GrantFiled: April 28, 2011Date of Patent: April 15, 2014Assignee: Cascade Water ServicesInventors: Eugene Klochkoff, Clive Ling, Steven Lerman
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Patent number: 8691086Abstract: A reverse osmosis system and method of operating the same includes a first pump receiving feed fluid at a first pressure and increasingly pressurizing the feed fluid to a second pressure higher than the first pressure. A membrane housing having an inlet, a membrane, a permeate outlet and a brine outlet. The inlet receiving feed fluid. A hydraulic energy management integration system (HEMI) having a turbine portion, a pump portion and a motor. The brine outlet fluid is in fluid communication with the turbine portion. The reverse osmosis system also includes a second pump and a controller controlling the motor to retard rotation of the HEMI while the first pump increasingly pressurizes the feed fluid to the second pressure.Type: GrantFiled: February 14, 2011Date of Patent: April 8, 2014Assignee: Fluid Equipment Development Company, LLCInventor: Eli Oklejas, Jr.
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Publication number: 20140083943Abstract: A device and method for detecting recirculation for an extracorporeal blood treatment apparatus and an apparatus with a device for detecting recirculation are based on targeted haemodilution by administration of a substituate bolus, causing a pressure change in venous and arterial branches of the extracorporeal circuit due to a viscosity change of flowing fluid. Recirculation is detected based on detection of the pressure change. The device includes a control unit cooperating with a device for conveying blood and a device for supplying substituate. The control unit provides an operating mode for detecting recirculation, in which blood flow rate is reduced during administration of a substituate bolus. With simultaneous substituate bolus administration and reduction of blood flow rate, the composition of fluid flow is optimised for detection of recirculation, so that fairly large pressure changes result in venous and arterial branches, thereby improving sensitivity and reliability of the measurement method.Type: ApplicationFiled: September 20, 2013Publication date: March 27, 2014Inventor: Thomas Nuernberger
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Patent number: 8679332Abstract: A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system without relying on a nano-scale sensor in the operating flow path. A main flow sensor is disposed in the main flow path between the pump and a flow-divider. A waste flow sensor is disposed in the waste flow path downstream of the splitter. The output signal of the waste flow sensor is subtracted from the output signal of the main flow sensor in a difference circuit. The difference signal is divided by the output signal from the main flow sensor in a divider circuit. The output of the divider circuit represents an empirical split ratio of the flow-divider and is independent of media composition.Type: GrantFiled: December 19, 2007Date of Patent: March 25, 2014Assignee: Waters Technology CorporationInventors: Geoff C. Gerhardt, Keith Fadgen
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Patent number: 8679333Abstract: A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate and precise flow delivery at capillary (<0.1 mL/min) and nano-scale (<1 ?L/min) HPLC flow rates.Type: GrantFiled: January 25, 2010Date of Patent: March 25, 2014Assignee: Waters Technologies CorporationInventors: Geoff C. Gerhardt, Joseph A. Luongo
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Patent number: 8673144Abstract: A liquid sample is prepared at a preparation site and then processed, e.g. in an HPLC column. The sample is prepared and conveyed to the device at a flow rate which is substantially less than the flow rate through the device. The different flow rates are preferably provided by variable rate working fluid supplies which drive the sample from the preparation site and through the device.Type: GrantFiled: November 24, 2009Date of Patent: March 18, 2014Assignee: DH Technologies Development Pte. Ltd.Inventors: David W. Neyer, David J. Rakestraw, Jason E. Rehm
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Patent number: 8658034Abstract: A mobile phase delivery device for use with high pressure liquid chromatography includes a manifold having a plurality of inlets, wherein each inlet is fluidly coupled with a solvent source. The manifold further has a mobile phase outlet that outputs a mobile phase, composed of solvent or solvent mixture, onto an analytical line. The device further includes at least one pump for delivering solvent to the manifold, and a fluid branch in the manifold that is located at a point downstream of the plurality of inlets, and is fluidly coupled with at least one of a pressure sensor and a purge valve.Type: GrantFiled: September 2, 2012Date of Patent: February 25, 2014Assignee: Bruker Michrom, Inc.Inventors: Kerry Nugent, David Kennedy
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Publication number: 20140014591Abstract: This disclosure is directed to the regulated injection of a chemical(s), solution(s) or material(s) hereafter referred to as chemicals into stormwater runoff, other surface waters or other fluid streams to promote the removal of a pollutant(s) or to alter the properties of the water. Specifically, and depending upon the types of chemicals injected, the physical, chemical and/or biological properties of the water can be altered. The invention provides a passive system to alter stormwater runoff or other surfaces. The system may be deployed at a remote site, such as a construction site, and implemented with minimal or zero external power requirements.Type: ApplicationFiled: May 24, 2013Publication date: January 16, 2014Inventors: Jason Robert Vogel, Daniel Eugene Storm, Billy J. Barfield, Wayne Ray Kiner, Karl Michael Garbrecht
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Patent number: 8628670Abstract: A method of treating water in order to minimize scaling and biomass buildup in water conduits or containers in which the treated water is used includes processing ambient air in a chamber including at least one ultraviolet light source to generate an output flow mixture of air and reactive oxygen species (ROS) gasses, controlling the at least one ultraviolet light source, a flow rate of the output flow mixture and an ROS gas ratio in the output flow mixture, mixing a water flow with the output flow mixture to realize a flow of water/ROS gas mixture and outputting the flow of water/ROS gas mixture as the treated water. Preferably, the processing includes generating reactive oxygen species (ROS) gasses in the output flow mixture including at least one of Super Oxide (O2?) Peroxide (—O2—), Hydroperoxide (HO2?), Hydroxyl Radicals (OH.), Ozone (O3?) and Molecular Oxygen (O2).Type: GrantFiled: July 19, 2010Date of Patent: January 14, 2014Assignee: Cascade Water ServicesInventors: Eugene Klochkoff, Clive Ling, Steven Lerman
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Patent number: 8623202Abstract: A method and system for wastewater treatment comprising a first treatment zone (11) fluidly connected to one or more further treatment zones (12, 13, 14), a membrane module (16) comprising a filter membrane positioned in or fluidly connected to the further treatment zone (14), a gravity settling device (15) fluidly connected to the first treatment zone (11) to receive overflow therefrom; and a flow control device (23) between the first treatment zone (11) and the gravity settling device (15) to control the flow of liquid therebetween.Type: GrantFiled: October 17, 2012Date of Patent: January 7, 2014Assignee: Siemens Water Technologies LLCInventor: Dennis J. Barnes
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Patent number: 8617393Abstract: A method and a device for supply of a dialyser in a dialysis unit with dialysis fluid is disclosed. At least one dialysis fluid concentrate is mixed with water to produce the dialysis fluid. The dialysis fluid concentrate is prepared in a reservoir unit in a given amount. A control and arithmetic unit calculates the dialysis fluid rate (Qd) such that, after a given treatment time (TB) has passed, a given residual amount of dialysis fluid concentrate or no residual amount remains in the reservoir unit. It is preferable to empty the reservoir unit by the end of treatment.Type: GrantFiled: June 14, 2013Date of Patent: December 31, 2013Assignee: Fresenius Medical Care Deutschland GmbHInventors: Gerard Remkes, Gerhard Wiesen
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Patent number: 8568586Abstract: The present invention provides automated systems and methods for monitoring column performance in process chromatography, and applications thereof. In an embodiment, column performance is monitored by generating a plurality of process values such as, for example, conductivity values or pH values with a detector during a chromatography step transition between a first mobile phase liquid and a second mobile phase liquid. The process values are transformed to form transformed process values in which noise present in the process values is suppressed. Column performance parameters are calculated based on the transformed process values and displayed during movement of the second mobile phase liquid through the chromatography column.Type: GrantFiled: January 23, 2009Date of Patent: October 29, 2013Assignee: Biogen Idec MA Inc.Inventors: Paul Cunnien, Joydeep Ganguly, Basav Ghosh, Asif Ladiwala, Robert Song, Jorg Thommes
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Publication number: 20130248450Abstract: A fluid filtration system comprising a cross-flow filter is arranged to permit a first pump to recirculate part of the retentate of the filter to the inlet of the cross-flow filter and a second pump to return part of the permeate to the inlet of the cross-flow filter. A third pump is configured supply source fluid to the inlet of the filter. The flow path between the second pump and the cross-flow filter inlet may include an adsorption filter that may selectively remove contaminants, toxins, or pathogens in the permeate. A controller may control the first, second and third pumps to provide predetermined flow ratios among the fluid flow paths of the system in order to achieve a desired filtration level. This system may be applicable to the removal of harmful substances from blood, by first separating the plasma from the blood and then removing harmful substances from the plasma.Type: ApplicationFiled: September 14, 2012Publication date: September 26, 2013Applicant: DEKA Products Limited PartnershipInventors: Rodney S. Kenley, Ryan K. LaRocque, Andrew A. Schnellinger
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Publication number: 20130248444Abstract: A method is disclosed for scaling control in a membrane system operation. The method can be performed by a model in the control system of a plant. The method can include selecting one or more antiscalants corresponding to one or more components of the scale, based on one or more of feed water condition, membrane material, membrane fouling status and a kinetic study relating to a reaction between the antiscalants and the components of the scale. The composition of one or more selected antiscalants can be estimated based on an overall scaling rate constant.Type: ApplicationFiled: May 14, 2013Publication date: September 26, 2013Applicant: ABB RESEARCH LTDInventors: Senthilmurugan SUBBIAH, Srinivas Mekapati, Mohan S. Kumar
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Publication number: 20130213890Abstract: Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module.Type: ApplicationFiled: August 15, 2012Publication date: August 22, 2013Applicant: Medtronic, Inc.Inventors: Thomas D. Kelly, SuPing Lyu, Bryant J. Pudil, Thomas E. Meyer
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Patent number: 8496824Abstract: A method and a device for supply of a dialyser in a dialysis unit with dialysis fluid is disclosed. At least one dialysis fluid concentrate is mixed with water to produce the dialysis fluid. The dialysis fluid concentrate is prepared in a reservoir unit in a given amount. A control and arithmetic unit calculates the dialysis fluid rate (Qd) such that, after a given treatment time (TB) has passed, a given residual amount of dialysis fluid concentrate or no residual amount remains in the reservoir unit. It is preferable to empty the reservoir unit by the end of treatment.Type: GrantFiled: January 14, 2004Date of Patent: July 30, 2013Assignee: Fresenius Medical Care Deutschland GmbHInventors: Gerard Remkes, Gerhard Wiesen
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Patent number: 8486196Abstract: Because an evaporating apparatus for use in an MOCVD film deposition system has a structure in which a plurality of gas passages brings in a gas from the upper direction, the apparatus has a difficulty to position a jet nozzle, and the apparatus is incapable of accurately controlling the pressure and flow rate of a carrier gas mixed with a raw material solution to be issued into an evaporating unit, and it is thus difficult to highly accurately control the composition of MOCVD films. A plurality of gas passages is arranged on a flat, disk-shaped plate. With this configuration, the accurate positioning of the jet nozzle can be made easier, and the composition of MOCVD films can be controlled highly accurately.Type: GrantFiled: May 15, 2008Date of Patent: July 16, 2013Assignees: Kabushiki Kaisha Watanabe ShokoInventors: Masayuki Toda, Masaki Kusuhara, Masaru Umeda, Mitsuru Fukagawa
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Patent number: 8425779Abstract: In a method for converting fluctuating energy into a stable energy supply, the fluctuating energy is derived from the group of solar energy, wind power, waves or water currents, this energy being delivered to a first pump being integrated in a pressure circuit for delivering stable energy and the pressure circuit comprising a pressure amplifier with a double-cone device being driven by the liquid flow circulated by the first pump. This allows the stabilization of fluctuating energy to be used e.g. in desalination plants without supplemental storage energy and without reverting to electric current conversion.Type: GrantFiled: March 6, 2007Date of Patent: April 23, 2013Assignee: DCT Double-Cone Technology AGInventor: John Stark
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Patent number: 8409442Abstract: A system for treating fractionated water from an oil and gas well. The system comprising a filter system, a diffusive membrane system, a plurality of membrane sensors, and at least one membrane controller. The filter system is fluidly connected to the diffusive membrane system, wherein the filter system comprises a plurality of straining filter banks. The diffusive membrane system comprises a plurality of membrane banks each having an inlet and an outlet. The plurality of membrane sensors are positioned at the outlet of each of the plurality of membrane banks, and the plurality of membrane sensors are configured to detect the total dissolved solids level at the outlet of each of the plurality of membrane banks.Type: GrantFiled: April 30, 2010Date of Patent: April 2, 2013Assignee: NG Innovations, Inc.Inventor: Donald W. Booth
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Publication number: 20130056419Abstract: A medical dialysis system including a filtration system configured to filter a water stream, a water purification system configured to purify the water stream in a non-batch process, a mixing system, and a dialyzer system. The mixing system includes a supply of dialysate components, a conductivity sensor positioned within a fluid pathway through which the water stream flows, and a control mechanism having a pump configured to control an amount of the one or more dialysate components added to the water stream from the supply. The mixing system can produce a stream of dialysate from mixing the one or more dialysate components with the water stream in a non-batch process. The dialyzer system includes a dialyzer, a plurality of pumps capable of pumping the stream of dialysate across the dialyzer, and another conductivity sensor positioned downstream of the dialyzer within a fluid pathway through which the water stream flows.Type: ApplicationFiled: August 29, 2012Publication date: March 7, 2013Inventor: James R. Curtis
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Patent number: 8382075Abstract: An air stripper in the form of an submerged gas evaporator or a submerged gas reactor that includes a vessel, a gas delivery tube partially disposed within the vessel to deliver a gas into the vessel and a contaminated liquid inlet that provides a contaminated liquid to the vessel at a rate sufficient to maintain a controlled constant level of process fluid within the vessel. A weir is disposed within the vessel adjacent the gas delivery tube to form a first fluid circulation path between a first weir end and a wall of the vessel and a second fluid circulation path between a second weir end and an upper end of the vessel. During operation, gas introduced through the tube mixes with the process fluid and the combined gas and fluid flow at a high rate with a high degree of turbulence along the first and second circulation paths defined around the weir, thereby promoting vigorous mixing and intimate contact between the gas and the process fluid.Type: GrantFiled: January 19, 2007Date of Patent: February 26, 2013Assignee: Heartland Technology Partners, LLCInventors: Bernard F. Duesel, Jr., Michael J. Rutsch