Abstract: The invention relates to a dialysis machine having a fluid system that has an inflow line for providing fresh dialyzing solution to a dialyzer and an outflow line for removing used dialyzing solution from the dialyzer, wherein the fluid system has a balancing system arranged between the inflow and outflow lines to balance the fluid volumes flowing through the lines, and wherein the fluid system has an ultrafiltration line that branches off from the outflow line between the dialyzer and the balancing system and has an ultrafiltration pump to be able to remove a defined volume of used dialyzing solution from the balance, and wherein an additional balancing chamber is provided that is arranged in a section of the inflow line disposed between the balancing system and the dialyzer or in a section of the outflow line disposed between the dialyzer and the branching of the ultrafiltration line.

Abstract: Systems relate to a reusable console system that can be used with a plurality of different types of disposable cassettes. The cassettes may be structured for different therapies, different fluid volumes, among others, or a combination thereof. The disposable cassette may include a plurality of fluid circuits. Each circuit may include a pump chamber disposed along the path. The disposable cassette and the panel of a console may be configured to mate so that each of the one or more actuators of the console align with a pump chamber of the disposable cassette. The console may be configured to control a flow of the fluid in the path in the cassette when the disposable cassette is mated on the panel. Because the console can be mated with different cassettes, the system can efficiently and accurately deliver different medical fluid therapies and/or different patient populations (e.g., pediatric and adult).

Abstract: The invention relates to a device (10) for degassing dialysis concentrates for automatic density measurement in mixing systems, comprising: an overflowable filter element (53), wherein the overflowable filter element (53) converts gas bubble-laden dialysis concentrate at the input end into a gas bubble-free dialysis concentrate at the output end. The invention also relates to a mixing system (M) having a device (10) according to the invention and a method for degassing dialysis concentrates for automatic density measurement in mixing systems (M), comprising the steps: Introducing (100) the dialysis concentrate laden with gas bubbles into the overflowable filter element (53), Filtering out (200) gases, Diverting (300) the gas bubble-free dialysis concentrate, Measuring (400) the density of the gas bubble-free dialysis concentrate.

Abstract: A process for a therapeutic bladder pressure estimator is operative with a pump connected, in sequence, to a first hose, a supply pressure sensor, a second hose, a bladder having an inlet coupled to the second hose, a bladder outlet coupled to a third hose of substantially equal length to the second hose, a return pressure sensor, and a fourth hose coupled to the return pressure sensor and returning fluid from the pump to the reservoir. The process forms an error signal from the difference between a setpoint and the average of the supply and return pressures. A head pressure measurement may be done by turning the pump off after a steady state reading is made.

Abstract: A dialysate mixing machine may be configured to make dialysate on demand using, among other things, a plurality of concentrates in solid tablet form. For example, a prescription may be received by the dialysate mixing machine indicating the particular chemical constituents and amounts of each chemical constituent to be included in the dialysate. Based on the prescription, the dialysate mixing machine can determine the number of tablets required for each chemical constituent (and, e.g., the required amounts of other chemical constituents that are not in tablet form). The tablets are automatically dispensed and mixed with purified water, bicarbonate, and sodium chloride in a mixing chamber to produce the dialysate according to the prescription. The dialysate mixing machine may be used with and/or coupled to a dialysis machine (e.g., a hemodialysis (HD) machine designed for home use) to provide the dialysate on demand for a dialysis treatment.

Abstract: Dialyzer systems can consolidate multiple technologies and functionalities of blood treatment systems in a significantly integrated fashion. For example, this disclosure describes dialyzer systems that include a magnetically driven and magnetically levitating pump rotor integrated into the dialyzer. Such a dialyzer can be used with treatment modules that include a magnetic field-generating pump drive unit. In some embodiments, the dialyzers include pressure sensor chambers with flexible membranes with which corresponding pressure transducers of the treatment modules can interface to detect arterial and/or venous pressures.

Abstract: A conductivity measurement device includes first and second conductivity measurement flow channels positioned in a fluid circuit and fluidly linked for fluid flow between the first and second conductivity measurement flow channels. A controller having a current source connected to the first and second conductivity channels applies alternating voltages at frequencies that are different, each being respective to one of the first and second conductivity cells.

Abstract: A sorbent cartridge that has at least one sensor located within the sorbent cartridge.

Abstract: A hemodialysis system is disclosed. The hemodialysis system includes a disposable set including a blood pumping tube, a fresh dialysate pumping tube, and a spent dialysate pumping tube. The hemodialysis system also includes a dialysis instrument including a blood pump head, a fresh dialysate pump head, a spent dialysate pump head, a first motor positioned and arranged to operate the blood pump head, a second motor positioned and arranged to operate the fresh dialysate pump head, and a third motor positioned and arranged to operate the spent dialysate pump head. When the disposable set is loaded into the dialysis instrument, the blood pumping tube comes into registry with the blood pump head, the fresh dialysate pumping tube comes into registry with the fresh dialysate pump head, and spent dialysate pumping tube comes into registry with the spent dialysate pump head.

Abstract: A sorbent canister utilized when performing a dialysis treatment during hemodialysis (HD) or peritoneal dialysis (PD) is provided. The sorbent canister includes inlet and outlet ports that include a threaded interface for connection to inlet and outlet tubes for circulation of dialysate through the sorbent canister. Upon disconnection from a dialysis machine, a pressure relief cap can be threaded onto the threaded interface to seal the fluid in the sorbent canister while allowing for off-gases to be expelled when a pressure within the sorbent canister exceeds a threshold pressure, thereby preventing a rupture in the canister body. In one embodiment, the pressure relief cap includes a deformable insert with a hole formed therein that is closed in an uncompressed state and opened in a compressed state. In another embodiment, the pressure relief cap includes a diaphragm that mates with a feature of the inlet or outlet port.

Abstract: Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

Abstract: A sterile fluid pathway connector includes a piercing member, a connector hub, and a pierceable seal; wherein at least a portion of the pierceable seal is configured to move from a first position in which the piercing member is retained within a sterile cavity between the pierceable seal and the connector hub, to a second position in which the pierceable seal has been penetrated by the piercing member. A filter may be utilized to enclose the sterile cavity from the outside environment. Such fluid pathway connections may be integrated into a fluid container having a barrel and a plunger seal. The components of the fluid pathway connector may further be capable of transmitting a signal to the user upon completion of fluid delivery, for example, upon contact between the plunger seal and the pierceable seal. A fluid delivery pump includes such integrated fluid pathway connectors and fluid containers.

Abstract: A pressure controller for a fluidic bladder has in sequence a pump, a first fluid line, a supply pressure sensor, a second fluid line, a bladder having an inlet coupled to the second fluid line, a bladder outlet coupled to a third fluid line of substantially equal length to the second fluid line, a return pressure sensor, and a fourth fluid line coupled to the return pressure sensor and returning fluid from the pump to the reservoir. A pressure estimate is formed by averaging the supply pressure and return pressure. The pressure controller receives a setpoint pressure as a command and data over a wireless channel, and computes a head pressure offset by turning the pump off and measuring the supply and return pressures.

Abstract: A device and method for monitoring an access to a patient, an extracorporeal blood circuit and/or a dialyzing fluid system includes a centrifugal pump for conveying blood or dialyzing fluid instead of an occluding pump. Centrifugal pumps bring about a large change in flow rate by even a small change in pressure difference across the pump. The device includes a measuring unit for measuring the flow rate of blood or dialyzing fluid conveyed by the centrifugal pump, and a control and computing unit configured to determine an incorrect vascular access or malfunction if a change in measured flow rate Q is more than a predetermined amount. For example, a small drop in pressure in the venous blood line leads to a marked increase in the flow rate of the centrifugal pump, which is used as a basis for the detection of an incorrect vascular access.

Abstract: A sterile container including at least one hollow fiber filter module, especially dialyzer, which is accommodated in a hermetically sealed holding volume of a primary package and includes a blood compartment delimited by a blood inlet opening and a blood outlet opening, wherein a plurality of hollow fiber filter modules is arranged in the primary package and the sterile barrier of the blood compartment of each hollow fiber filter module inside the primary package is implemented by caps which close the blood inlet opening and the blood outlet opening of each hollow fiber filter module. A method of manufacturing such sterile container is also disclosed.

Abstract: A flowmeter (5) is provided having a housing (28) configured to accept a flow of a process material. A diaphragm (18) is disposed in the housing (28), and is deformable by the flow of the process material. A sensor (48) is configured to detect a deformation in the diaphragm (18), and the flowmeter (5) is configured to measure the flow of the process material.

Abstract: A dialysis monitor with a treatment fluid path configured to provide treatment fluid to a dialyzer when dialysis treatment is performed by the dialysis monitor is provided. A battery unit is connected to a controller and at least a portion of the functional elements of the dialysis monitor in order to provide back-up power should the supply of external power be discontinued. Energy of the battery unit is used to provide energy to the heater in preparation for and/or at least partly during thermal disinfection of the treatment fluid path or when starting up the preparation of treatment fluid thereby shortening the time required for the thermal disinfection and the starting up of the preparation of treatment fluid, respectively.

Abstract: A fluid preparation system has a sealed sterilized fluid circuit with a sealed sterilized container with a conductivity sensor in communication with an interior of said container. Further, at least one sealed connector is adapted for adding fluid to said container, and at least one sealed connector is adapted for removing fluid from said container. The conductivity sensor is contained in a test line in communication with said interior and is adapted to be connected to a source of suction thereby to draw a sample of contents of said container. Furthermore, the test line may have a check valve to prevent ingress of contaminants into said container, and the sealed connector is adapted for adding fluid to said container and may have an inline sterile filter. Furthermore, the system may have a controller that controls pumping actuators.

Abstract: Provided is a temperature-based dialysate regeneration device for regulating a temperature of dialysate discharged from a hemodialyzer to remove uremic toxins and waste therefrom, the temperature-based dialysate regeneration device including: a Joule-Thomson refrigerator, including a compressor, condenser, expander and evaporator, an adsorbent column, and a dialysate heat exchanger in which heat transfer occurs between dialysates. The refrigerant used for the JT refrigerator may be a mixture of two or more refrigerants to enhance the heat transfer generated by the latent heat in the evaporator and the condenser.

Abstract: An infusion system includes a double action infusion pump. The pump includes a cylinder and a reciprocating piston received within the cylinder, the reciprocating piston separating a first pump chamber from a second pump chamber of the cylinder. A reciprocating motor is coupled with the reciprocating piston, and the first and second pump chambers alternate between filling and evacuating conditions with reciprocation of the reciprocating piston through operation of the reciprocating motor, and the speed of reciprocation is varied to provide a continuous output of fluid between the first and second pump chambers. A fluid source and a catheter are optionally coupled with the double action infusion pump. The catheter includes one or more infusion ports near a catheter distal portion, and the one or more infusion ports receive and expel the continuous output of fluid from the double action infusion pump.

Abstract: An infusion system includes a double action infusion pump. The pump includes a cylinder and a reciprocating piston received within the cylinder, the reciprocating piston separating a first pump chamber from a second pump chamber of the cylinder. A reciprocating motor is coupled with the reciprocating piston, and the first and second pump chambers alternate between filling and evacuating conditions with reciprocation of the reciprocating piston through operation of the reciprocating motor, and the speed of reciprocation is varied to provide a continuous output of fluid between the first and second pump chambers. A fluid source and a catheter are optionally coupled with the double action infusion pump. The catheter includes one or more infusion ports near a catheter distal portion, and the one or more infusion ports receive and expel the continuous output of fluid from the double action infusion pump.

Abstract: Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end.

Abstract: Dialysis systems including a water treatment unit preferably of the osmosis type, a drain line, and a heat exchanger are disclosed. A water supply line is connected to an outlet of the water treatment unit. The water supply line includes branch connections to which dialyzers are selectively fluid-coupled. Used-up dialysis fluid can be discharged from fluid-coupled dialyzers through the drain line. The heat exchanger, which is external to the dialyzers, connected on one side to the water supply line directly upstream of the branch connections and on the other side to the drain line.

Abstract: A dialysis machine that includes a valve member having a deformable area configured to deform outwardly away when pressurized fluid is introduced into the valve member. The valve member is configured so that, when a dialysis fluid cassette is disposed in a cassette compartment of the dialysis machine and pressurized fluid is introduced into the valve member, the deformable area obstructs a fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough.

Abstract: A dialysis machine useful in hemodialysis can process or treat a reverse osmosis water flow received through the machine to prepare a dialysate. The machine can include an additive source to introduce an additive, such as bicarbonate, to the reverse osmosis water flow. The machine can include a sensor in fluid communication with the additive introduction point that can measure the conductivity or similar characteristic of the solution. During a first time period when additive is actively introduced to the reverse osmosis water flow, the sensor can measure a relatively high conductivity value. During a second time period when additive is not introduced to the reverse osmosis water flow, the sensor can measure a relatively low conductivity value. The dialysis machine can include a controller that processes these measurements to assist control and operation of the machine.

Abstract: Methods include monitoring blood pH or electrolyte levels and setting initial fluid parameters, such as dialysate fluid parameters or replacement fluid parameters, for a blood fluid removal session based the monitored data. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.

Abstract: Illustrative embodiments of microdevices and methods of manufacturing such microdevices are disclosed. In at least one illustrative embodiment, a method of manufacturing one or more microdevices may include forming a liquid dispersion containing cellulose nanocrystals (CNC), depositing the liquid dispersion containing the CNC on a substrate, drying the liquid dispersion containing the CNC to form a solid film on the substrate, where the liquid dispersion contains a sufficient concentration of CNC to form a continuous solid film having a controlled microstructure, and processing the solid film to form the one or more microdevices on the substrate.

Abstract: The present invention constitutes dialysate formulations that are suitable for use in preparing dialysate solutions for use in batch and/or proportioning systems and for improving dialysis efficiency by reducing or preventing clotting of the dialysis flow paths. The dialysate chemical formulations for one batch of dialysate comprise an acid concentrate stored in a first vessel, and a citrate-containing bicarbonate concentrate stored in a second vessel. The contents of the first and second vessels are emptied into a dialysate preparation tank and mixed with water to form a batch quantity of dialysate solution. Alternately, a dry acid and/or a dry citrate-containing base concentrates are dissolved separately in measured quantities of water to form liquid concentrates which are then used in conjunction with a proportioning machine to generate on-line a final dialysis solution stream.

Abstract: The present invention relates to a means of dialysis for removing protein-bound substances from a biological fluid, especially blood or blood plasma, which contains at least one means for solubilizing protein-binding substances to be removed into the biological fluid and/or dialysis fluid, and to a process for removing protein-bound substances from a biological fluid.

Abstract: A blood circuit assembly for a dialysis unit may include an organizing tray, a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient, an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit, a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit, and a pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient.

Abstract: A dialysis system includes a fresh dialysis fluid membrane pump; a spent dialysis fluid membrane pump; a first balance chamber having a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid membrane pump and a spent dialysis fluid compartment connected fluidly to the spent dialysis fluid membrane pump; a second balance chamber having a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid membrane pump and a spent dialysis fluid compartment connected fluidly to the spent dialysis fluid membrane pump; and a dialysis fluid cassette, wherein at least one of the fresh dialysis fluid membrane pump, the spent dialysis fluid membrane pump, the first balance chamber and the second balance chamber includes a fluid receiving portion provided in the dialysis fluid cassette.

Abstract: The invention is directed to a method of determining a dosage of phosphorus binder for a patient undergoing dialysis treatment to achieve a pre-dialysis serum phosphorus concentration within a desired concentration range while achieving a desired net accumulation of calcium. The method includes determining the dosage of phosphorus binder that will achieve pre-dialysis serum phosphorus concentration of the patient that is within the desired concentration range while accounting for the change in the amount of phosphorus removed by the dialysis treatment when the pre-dialysis serum phosphorus concentration of the patient is within the desired concentration range, determining a dialysate calcium concentration that will result in the desired net accumulation of calcium over a complete dialysis cycle, and dialyzing the patient with a dialysate containing a calcium concentration based upon that determination.

Abstract: Provided is a valuable-metal recovery method for recovering metals from lithium ion batteries using comparatively simple equipment and without using a cumbersome process. In said method, a positive electrode material from lithium ion batteries, containing lithium and a transition metal, is dissolved in an acidic solution, thereby generating lithium ions and ions of the transition metal in the acidic solution. Said acidic solution and a recovery liquid are then made to flow with an anion-permeable membrane interposed therebetween, causing the lithium ions to permeate from the acidic solution to recovery solution. Lithium ions are then recovered from the recovery liquid containing dissolved lithium ions.

Abstract: A hemodialysis machine comprising a dialysate flow path for delivering a flow of dialysate solution through a dialyser, the flow path including a flow balancer for achieving a balance in the dialysate solution flow volume observed between an inlet and an outlet of the dialyser over the course of a treatment, the flow balancer comprising a first flow balance pump having an inlet valve and an outlet valve and a second flow balance pump having an inlet valve and an outlet valve, wherein the flow path further includes a flow restrictor means downstream of the flow balance pumps to reduce the pressure difference across the valves in the dialysate flow path.

Abstract: A dialysis machine includes a blood circuit, a dialysate circuit, and a dialyzer placed in communication with the blood circuit and the dialysate circuit. The dialysis machine includes a priming sequence in which dialysate is used to prime a first portion of the dialysate circuit and a physiologically compatible solution, other than dialysate, is used to prime a second portion of the dialysate circuit, the dialyzer and the blood circuit.

Abstract: A dialysis machine that includes a valve member having a deformable area configured to deform outwardly away when pressurized fluid is introduced into the valve member. The valve member is configured so that, when a dialysis fluid cassette is disposed in a cassette compartment of the dialysis machine and pressurized fluid is introduced into the valve member, the deformable area obstructs a fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough.

Abstract: A dialysate regeneration chamber is provided. In one embodiment, the dialysate regeneration chamber may include a toxin trap configured to selectively trap toxins and repel select cations. In another embodiment, generating a toxin trap may include oxidizing an activated carbon fiber and attaching a fatty acid to the oxidized activated carbon fiber to generate an ion-selective barrier, wherein the fatty acid extends away from the activated carbon fiber.

Abstract: This disclosure relates to early detection of low bicarbonate level. In certain aspects, a method includes receiving a first signal from a conductivity detector connected to a line through which a solution of salt concentrate and fluid flows and determining a first conductivity of the solution based on the first signal. The method also includes receiving a second signal from the conductivity detector at a time after receiving the first signal, determining a second conductivity of the solution based on the second signal, and determining whether the second conductivity is less than the first conductivity by at least a threshold amount.

Abstract: This disclosure generally relates to dialysis systems and related methods. In one aspect of the invention, a dialysis system includes a device configured so that a medical fluid can pass therethrough, and the device is adapted to remove one or more substances from the medical fluid as the medical fluid passes through the device. The dialysis system can also include a sodium control system adapted to alter a sodium concentration of the medical fluid.

Abstract: A dialyzer composed of: first and second dialyzation chambers, and an intermediate chamber interposed between the first and second dialyzation chambers. Each dialyzation chamber has opposed first and second ends and contains a filter member that separates the chamber into a blood compartment and a dialysate compartment. Each of the compartments extends between first and second ends. Each of the chambers has a respective one of a blood inlet or outlet and a dialysate inlet or outlet arranged so that blood and dialysate flow in counter-current to one another in both chambers. The intermediate chamber is connected to form a dialysate-free blood flow passage between the blood compartments.

Abstract: A blood circuit capable of automatically performing priming for safe treatments. The blood circuit includes: a hemofilter (56) purifying blood; a blood removal line that has an end connected to an inlet of the hemofilter (56) and that includes a first blood removal line (84), a second blood removal line (88), and a third blood removal line (89); a blood return line that has an end connected to an outlet of the hemofilter (56) and that includes the first blood return line (92) and the second blood return line (94); and an anticoagulant (bypass) line (90) reducing a difference between (a) a pressure of a priming fluid flowing in the blood removal line and (b) a pressure of the priming fluid flowing in the blood return line.

Abstract: An apparatus for purifying body fluid with solution including a casing having first and second input and output ports and dual safety or check valves monolithically formed with the casing that operate in conjunction with a dialysis machine or other apparatus used in hemodialysis is disclosed. The dual safety valves are configured at the input and output ports of a dialyzer such that the apparatus allows body fluid to move in one direction. This configuration prevents the reverse flow of body fluid back into the apparatus. A method for purifying body fluid with solution using an apparatus is further disclosed.

Abstract: A dialysis service box for centralized control and plumbing arrangement of a dialysis machine is disclosed. The dialysis service box includes a plumbing arrangement having a supply inlet for supplying a fluid to the dialysis machine, a backflow preventer for preventing retrograde flow through the plumbing arrangement, a trap primer for maintaining a trap seal designed to prevent waste gases from flowing into the dialysis service box and a waste connection for allowing waste from the dialysis machine to exit. The dialysis service box can be universally installed to operate, control and adjust any dialysis machine that requires supply connection, waste connection, backflow preventer and trap primer, or any combination of the foregoing.

Abstract: A dialysis cell is provided for the measurement of free thyroxine. The dialysis cell preferably includes a polyhedral housing including a top, a bottom and four sides. The dialysis cell is made up of a buffer portion and serum portion. The buffer portion includes a cavity and the serum portion includes a cavity which, when the buffer portion and serum portion are assembled together, form a central chamber. The central chamber is divided by a vertically aligned dialysis membrane held in place by two O-rings. Buffer is introduced into the dialysis cell's buffer portion through a buffer inlet extending from the dialysis cell's top side to the buffer portion's cavity. Similarly, serum is introduced into the serum portion through an inlet which extends from an opening formed on the dialysis cell's top to the serum portion's cavity.

Abstract: The present application relates to a molecular exchange device (1) for use with an analysis and control apparatus and a method of manufacturing a molecular exchange device.

Abstract: An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine.

Abstract: Dialysis treatment devices and methods for removing urea from dialysis waste streams are provided. In a general embodiment, the present disclosure provides a dialysis treatment device including: 1) a first filter having a filtration membrane, 2) a urea removal unit having urease and in fluid communication with the first filter, and 3) a second filter having an ion rejection membrane and in fluid communication with the first filter and the urea removal unit.

Abstract: A method and device are provided for determining the transmembrane pressure during an extracorporeal blood treatment in which blood flows at a defined blood flow rate through an arterial blood conduit of an extracorporeal blood circuit into the inlet of a first chamber of a dialyzer, which is divided by a semipermeable membrane into the first chamber and a second chamber, and flows through a venous blood conduit from the outlet of the first chamber of the dialyzer, while dialysis liquid flows through a dialysis liquid supply conduit into the inlet of the second chamber of the dialyzer and flows through a dialaysis liquid discharge conduit from the outlet of the second chamber of the dialyzer.

Abstract: A dialysis machine, in particular a peritoneal dialysis machine, to which a fluid system having a multi-chamber container with at least two chambers with individual solutions separated by a partition arrangement to be opened mechanically can be coupled includes a controller and at least one sensor for the determination of a measured variable in the fluid system. The controller has an apparatus for the automatic checking of the proper opening of the partition arrangement with reference to the measured variable determined by the sensor.

Abstract: A kidney failure treatment system includes: (i) a dialysate supply; (ii) a weighing device; a control container coupled operably to the weighing device; (iii) a diffusion membrane; (iv) a drain; first and second pumps; (v) a first fluid conduit coupled fluidly to the dialysate supply and the diffusion membrane, the first fluid conduit coupled operably to the first pump; (vi) a second fluid conduit coupled fluidly to the control container and the drain, the second fluid conduit coupled operably to the first pump; and (vii) a third fluid conduit coupled fluidly to the diffusion membrane and the control conduit, the third fluid conduit coupled operably to the second pump.