With Individual Article Container Or Support Patents (Class 210/361)
  • Patent number: 11654631
    Abstract: The present disclosure is related to a processing carrier module comprising a carrier layer and a container. The carrier layer comprises a carrier surface, a first lateral surface, and a second lateral surface. The first lateral surface is connected to carrier surface and has at least one first protruding structure. The second lateral surface is connected to carrier surface and has at least one second protruding structure. The first lateral surface is opposite to the second lateral surface. The container comprises at least one first fastening structure and at least one second fastening structure. The first fastening structure and the second fastening structure are respectively disposed on opposite sides of the container. The first fastening structure engages with the first protruding structure, and the second fastening structure engages with the second protruding structure.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: May 23, 2023
    Assignee: TPK Glass Solutions (Xiamen) Inc.
    Inventors: Feng Ming Chen, Zhi Min Shao, Jin Run Lin
  • Patent number: 11338283
    Abstract: A kit for centrifugal isolation of a fraction of interest from a multi-component composition according to density, comprising: a separation chamber (200) having an inlet (210) for introducing the multi-component composition and a base through-hole (220); characterized in that the separation chamber (200) comprises: an inlet section (211) communicating with the inlet (210), a base section (212) communicating with the base through-hole (220), wherein the inlet section (211) and the base section (212) communicate with each other via a necked duct (230) for detaching the inlet section (211) and the base section (212) at the necked duct (230), wherein the separation chamber (200) has a form of a syringe in which the inlet of the separation chamber (200) is connectable with an extension nozzle or needle (215) for drawing the multi-component composition, and wherein the kit further comprises a plunger (240) for embedding and being slidably moved within the base section (212) of the separation chamber (200), wherein
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: May 24, 2022
    Inventors: Dominik Olbrzymek, Jakub Olbrzymek
  • Patent number: 11243513
    Abstract: Transport of physical objects is controlled based on scanning of encoded images. In one approach, an encoded image on a physical object is scanned to obtain parameters. The parameters include specifications for a product to be made by a manufacturing process. One or more rules are generated using the parameters and then stored in a database. The database is queried to determine whether the product conforms to the one or more rules. For example, the query may include data regarding characteristics of the final product and/or the manufacturing process. In response to determining that the product conforms to the rules, the product is transported to a distribution facility.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: February 8, 2022
    Assignee: Micron Technology, Inc.
    Inventor: Giuseppe Principato
  • Patent number: 11147418
    Abstract: A fryer includes a cooking chamber for holding a cooking medium at least one heating element positioned within the cooking chamber, and a chain conveyor for selectively advancing food product through the cooking chamber along a movement path. The chain conveyor includes first and second chains coupled together by a plurality of baskets extending therebetween. The movement path includes a series of legs, including a first leg wherein the food product moves substantially vertically from above the cooking medium to a greatest depth within the cooking medium and including a second leg subsequent to the first leg wherein the food product moves substantially horizontally at the greatest depth within the cooking medium. Automated filtering systems and methods for removing debris from cooking medium are also provided.
    Type: Grant
    Filed: April 4, 2018
    Date of Patent: October 19, 2021
    Assignee: Henny Penny Corporation
    Inventors: William M. Casey, Charles Leader, Robert Panning, Bruce Miller
  • Patent number: 11022622
    Abstract: The invention provides a high-throughput screening system based on multi-manipulators, and belongs to the field of biotechnology and detection equipment. A high-throughput screening system based on multi-manipulators, comprises of the first manipulator, sampler, pipette, plate washer, microplate reader, the second manipulator, centrifuge, deep-well plate library, waste shallow-well plate barrel, shallow-well plate library, waste needle plate barrel, needle library, waste deep-well plate barrel, collection box. The present invention is a combination of microbiology and mechanics. The aim of the invention is to realize the automation and intelligentization of the high throughput screening experiment, effectively improve the experimental accuracy, reliability and efficiency. It contributes to the development of high throughput screening technology for microorganisms and drugs.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: June 1, 2021
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jingwen Zhou, Jian Chen, Meng Ning, Guocheng Du, Weizhu Zeng, Xiaomei Cao, Qiuju Zhang, Jun Fang
  • Patent number: 10947132
    Abstract: A photocatalytic reaction unit for removing dissolved metals from a wastewater stream, including a photocatalytic reaction vessel having an inlet and an outlet for providing passage of the wastewater stream into and out of the photocatalytic reaction vessel; a photocatalyst for mixing with the wastewater stream; and an ultraviolet light source for emitting ultraviolet light into the photocatalytic reaction vessel.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: March 16, 2021
    Assignee: CARBONXT, INC.
    Inventors: David W. Mazyek, Heather McKenna, Christine O. Valcarce
  • Patent number: 10941055
    Abstract: According to the present disclosure, a photoelectrochemical cell for wastewater treatment is disclosed. A method of fabricating such a photoelectrochemical cell is also disclosed.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: March 9, 2021
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Olivier Patrick Lefebvre, Emmanuel Mousset, Zuxin Wang
  • Patent number: 10871427
    Abstract: A biological liquid collection vessel is adapted to contain a biological liquid to be centrifuged. The collection vessel has a vessel body having an open upper end and a closed lower end, a continuous wall, a target area at the upper end, and a solids area at the lower end that is connected to the target area. The target area is extended in length. In some embodiments, a volume capacity of both of the target area and the solids area are configured so that a red blood cell portion of the centrifuged biological liquid (e.g., blood) is substantially contained in the solids area, and the serum or plasma portion of the centrifuged biological liquid is substantially contained in the target area. Methods of and systems using the liquid collection vessels are provided, as are other aspects.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: December 22, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Alex Hsu, Scott Salmon, Radu Saftoiu
  • Patent number: 10760115
    Abstract: A specimen disrupting apparatus includes: a drive unit that rotates the lower portion of a container having a solution that includes a specimen, a great number of small diameter beads, and a large diameter bead stored therein; and a control unit that controls the drive unit. The control unit controls the drive unit such that the lower portion of the container rotates at two or more different rotational speeds which are changed continuously.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: September 1, 2020
    Assignee: FUJIFILM WAKO PURE CHEMICAL CORPORATION
    Inventors: Akito Yoneda, Tomohisa Kawabata, Yoichi Endo, Daisuke Hibe, Mikio Tsuyuki, Tatsuyuki Denawa
  • Patent number: 10267712
    Abstract: A centrifugal smearing device including a sealed rotating container that houses a chamber with a slide glass removably attached for holding a liquid sample to smear cells with a centrifugal force onto the slide glass, and a base housing the sealed rotating container and including rotational driving means for rotating the sealed rotating container, the sealed rotating container includes a main body capable of housing the chamber and a lid for closing an upper surface opening portion of the main body, a seal portion for sealing a space between the main body and the end face of the upper face opening portion is provided on an outer circumferential edge of the lid, and a scattering protection wall is formed at an inside of the seal portion so as to protrude downward to hide the seal portion from inside so that a liquid does not scatter onto the seal portion.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: April 23, 2019
    Assignees: SAKURA SEIKI CO., LTD., SAKURA FINETEK JAPAN CO., LTD.
    Inventors: Matsumi Toya, Tadashi Toufukuji
  • Patent number: 9829418
    Abstract: The present invention addresses the problem of providing a centrifugal smearing device and a sealed rotating container in which liquid components do not leak to an outside of the sealed rotating container. To solve this problem, in a centrifugal smearing device (30) including a sealed rotating container (34) that houses a chamber (10) with a slide glass removably attached for holding the liquid sample to smear cells in the liquid sample with a centrifugal force onto the slide glass, and a base (31) housing the sealed rotating container (34) and including rotational driving means (32) for rotating the sealed rotating container (34), the sealed rotating container (34) includes a main body (40) capable of housing the chamber (10) and a lid (42) for closing an upper surface opening portion of the main body (40), and has a storage section (46) for storing liquid scattered from the chamber (10) during being centrifuged, formed on an inside face of the main body (40).
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: November 28, 2017
    Assignees: SAKURA SEIKI CO., LTD., SAKURA FINETEK JAPAN CO., LTD.
    Inventors: Matsumi Toya, Tetsu Nagabayashi
  • Patent number: 9649579
    Abstract: A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: May 16, 2017
    Assignees: Hanuman LLC, Biomet Biologics, LLC
    Inventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
  • Patent number: 9629342
    Abstract: A beekeeping apparatus includes a bottom side having an arcuate groove defined therein, the arcuate groove being sized and dimensioned to correspond to the rim of a repository; and a top side including a recessed area defined therein, the recessed area being sized and dimensioned to correspond to a beekeeping frame, and a plurality of generally rectangular openings defined through the recessed area, the rectangular openings each being sized and dimensioned to receive and retain a portion of a beekeeping frame, and collectively being sized and dimensioned to receive and retain portions of different sizes of beekeeping frames.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: April 25, 2017
    Inventor: Vallie Hayden McMahon, III
  • Patent number: 8950586
    Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: February 10, 2015
    Assignee: Hanuman LLC
    Inventors: Randel Dorian, Richard W. Storrs, Scott R. King
  • Patent number: 8764992
    Abstract: A method of fractionating a dispersion of oxidic nanoparticles wherein at least one step of the method is a membrane crossflow filtration step, the flow of the dispersion over the membrane being brought about by means of driven rotating parts; and dispersions of oxidic nanoparticles that are obtainable by the method.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: July 1, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Roland Wursche, Goetz Baumgarten, Wolfgang Lortz, Michael Kroell
  • Patent number: 8545428
    Abstract: Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed either by pump or passively by gravity feed, through various filtration elements from a fluid source to a treatment fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment which provides multiple benefits and liabilities to overcome, as discussed herein. Mechanisms for preparing pure water for infusion or medicaments are described such as elimination of chlorine and colloidal aluminum. Also various control mechanisms to help avoid contamination are describe.
    Type: Grant
    Filed: September 5, 2012
    Date of Patent: October 1, 2013
    Assignee: Nxstage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Brian C. Green, Dennis M. Treu, Christopher S. McDowell, Goetz Friederichs
  • Patent number: 8474630
    Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: July 2, 2013
    Assignee: Hanuman, LLC
    Inventors: Randel Dorian, Scott R. King, Richard Wood Storrs
  • Patent number: 8187477
    Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: May 29, 2012
    Assignees: Hanuman, LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Scott R. King, Richard W. Storrs
  • Patent number: 8167139
    Abstract: The invention includes compositions of stem and progenitor cells recovered from bone marrow or cord blood containing most of the viable CD34+ cells and substantially depleted of red blood cells resident in the original sample, without any xenobiotic additives to aid cell separation. The invention also includes a system and method for preparing the compositions. The system includes a bag set and a processing device, which utilizes an optical sensor, microcontroller, servo motor, accelerometer, load cell, and battery. The system and method utilize centrifugation to stratify the cells into layers and then separate and transfer the stem cells into a stem cell bag. The processing device's microcontroller receives input from the device's accelerometer, load cell and optical sensor to direct the metering valve in the bag set to open and close to permit the transfer of as many stems cells as possible with as few red cells as possible.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: May 1, 2012
    Assignee: ThermoGenesis Corp.
    Inventors: Philip H. Coelho, Bruce A. Baker, John R. Chapman, Junzhi Li, Prince Emmanuel, Robert S. Childers
  • Patent number: 8151996
    Abstract: Contemplated whole blood separators tubes include a curable composition with a density intermediate to the density of serum and the cell-containing fraction. After centrifugation, the curable composition is located between the serum and the cell-containing fraction and preferably irradiated with UV light to initiate a curing reaction in which the curable composition solidifies to a barrier that is immobilized and resistant to breakdown at freezing temperatures and extended storage.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: April 10, 2012
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 8087516
    Abstract: A new device, method, and system are disclosed that provide for removal of undesired materials from a contaminated fluid. Materials present in the fluids are kept in motion in one or more filter cassettes that include disc aerators that improve contact times with the sorbents and that rotate the filter media to pump contaminated water through the filter media for treatment of the contaminated fluids. The device and system provide containment of sorbent fines that keeps the filter media free from clogging.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: January 3, 2012
    Assignee: Battelle Memorial Institute
    Inventor: Henry O. Pate
  • Patent number: 8066127
    Abstract: An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. The sensor may be reading one or more of the following characteristics: infrared, optics, density, weight, radioactive, fluorescence, color, magnetism, ultrasonic, capacitance wherein the characteristic is inherent in the blood and blood component or is an additive. Each component may then be separated into its own storage container. The preferred sensors include optics and weight.
    Type: Grant
    Filed: August 16, 2005
    Date of Patent: November 29, 2011
    Assignee: ThermoGenesis Corp.
    Inventors: Philip H. Coelho, Eric Sommer, Richard Klosinski, Jim Hobbs, Bruce Baker, Brian Malone
  • Patent number: 8057377
    Abstract: A bag loader for loading and unloading at least one satellite bag into and from the central compartment of a rotor of an apparatus for separating a composite liquid into at least two components comprises an upper part for removably securing an upper portion of at least one satellite bag; a lower part comprising a receptacle; and an intermediate part connecting the upper part to the lower part and exposing an intermediate portion of a satellite bag.
    Type: Grant
    Filed: August 14, 2006
    Date of Patent: November 15, 2011
    Assignee: CaridianBCT, Inc
    Inventors: Brian M. Holmes, Johan-Petter Hagström, Charles L. Hake
  • Patent number: 7837884
    Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: November 23, 2010
    Assignee: Hanuman, LLC
    Inventors: Randel Dorian, Scott R. King, Richard Wood Storrs
  • Patent number: 7780861
    Abstract: Contemplated whole blood separators tubes include a curable composition with a density intermediate to the density of serum and the cell-containing fraction. After centrifugation, the curable composition is located between the serum and the cell-containing fraction and preferably irradiated with UV light to initiate a curing reaction in which the curable composition solidifies to a barrier that is immobilized and resistant to breakdown at freezing temperatures and extended storage.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: August 24, 2010
    Assignee: The Regents of University of California
    Inventor: Jane Emerson
  • Patent number: 7470371
    Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Platelets are then removed from the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: December 30, 2008
    Assignee: Hanuman LLC
    Inventors: Randel Dorian, Scott R. King, Richard Wood Storrs
  • Patent number: 6616507
    Abstract: A centrifugal honey extractor comprising: (a) a frame supporting apparatus (12), and (b) an outer support structure (10). The outer support structure (10) provides vertical and lateral support for a removable flexible membrane (26) which becomes the inner wall of the outer support structure (10) and the surface which collects the honey as it is flung outwardly by centrifugal force from the honeycomb. The frame supporting apparatus (12) is constructed with a rigid annular cylinder center support (12d), which provides a non-flexible rotating apparatus that can be supported entirely by the top of the outer support structure (10). During operation the extracted honey will collect against the removable flexible membrane (26) where it will flow downwardly and through the outlet opening (32) in the bottom of the outer support structure (10). After the honey extraction operation the removable flexible membrane (26) is discarded eliminating the cleaning of the outer container.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: September 9, 2003
    Inventor: Frederick J. Swaney
  • Patent number: 6375855
    Abstract: A device for concentrating and/or purifying macromolecules in a solution has a concentration chamber (1) with a sample reservoir (2) for a liquid sample to be processed, a filter (3) for filtering the liquid sample, and a filtrate container (4) for collecting the filtrate. A gas pressure differential is created and maintained across the filter and a sealing cap (5) for the sample reservoir (2), which has an opening (6) for permitting gas flow in one direction and blocking aerosol or liquid flow in an opposed direction. The present invention also provides apparatus and methods employing the device.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: April 23, 2002
    Assignee: Vivascience, AG
    Inventor: Vincenzo Vassarotti
  • Patent number: 6077431
    Abstract: A process is disclosed which comprises the steps of: slurrying sludge to be treated; applying ultrasonic radiation to the slurry to decompose dioxins contained in the sludge in a reaction field developed by the application of the ultrasonic radiation and to transfer pollutants including the resulting decomposition products from a solid phase to a liquid phase of the slurry; and separating the slurry into the liquid phase containing the pollutants and the solid phase free from dioxins by solid-liquid separation means.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: June 20, 2000
    Assignee: Kubota Corporation
    Inventors: Toshio Kawanishi, Yasuo Horii, Koichi Nakagawa
  • Patent number: 6029569
    Abstract: An improved method and apparatus for the removal of solid contaminants which utilizes at least one rotating mesh screen container designed to pass the food therethrough while trapping the solid contaminant. The rotation of the cylindrically-shaped mesh screen causes the food to pass through because of the centrifugal force. The addition of a second mesh or membrane-like placed around the first screen but rotated in the opposite direction is also utilized to trap solid contaminants which are large enough to be trapped by the mesh screen when it is not oriented so as to pass through the screens along its length. Different spacings in mesh and different rotation velocities are utilized to change contaminant screen characteristics.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: February 29, 2000
    Inventor: Scott Packer
  • Patent number: 5961842
    Abstract: Blood separation systems and methods employ a rotating chamber. The chamber includes an inlet region where whole blood enters for centrifugal separation into packed red blood cells, a plasma constituent, and an interface carrying mononuclear cells between the packed red blood cells and the plasma constituent. The packed red blood cells in the chamber have a hematocrit value H.sub.PRBC. A controller operates in a first mode to convey whole blood into the inlet region while removing packed red blood cells and the plasma constituent from the chamber and while maintaining the interface within the chamber. The controller also operates in the first mode to maintain a set H.sub.PRBC by conveying packed red blood cells into the inlet region.
    Type: Grant
    Filed: July 1, 1997
    Date of Patent: October 5, 1999
    Assignee: Baxter International Inc.
    Inventors: Kyungyoon Min, Richard I Brown, Robert J Cantu, Daniel F Bischof, William H Cork
  • Patent number: 5942129
    Abstract: There is provided an apparatus and method for using a centrifuge to apply a treatment liquid, such as a fixative agent, to a specimen undergoing centrifugation analysis. There is provided a centrifuge sample chamber with a mounting flange for engagement with a microscope slide, so that specimen material is centrifuged to the slide for inspection. The sample chamber has an upper cavity and a lower specimen holding portion which are connected by a fluid passage. The specimen holding portion ideally includes a lower cavity with a lower leg extending down therefrom for holding the specimen prior to centrifugation. An upper hollow leg in communication with the upper cavity holds the treatment liquid while the chamber is at rest prior to centrifugation. Activation of the centrifuge tilts the chamber to incline the upper and lower legs, so that the treatment liquid flows into, and is held within, the upper cavity by centrifugal force.
    Type: Grant
    Filed: July 17, 1997
    Date of Patent: August 24, 1999
    Assignee: Shandon, Inc.
    Inventor: William J. Hayes
  • Patent number: 5914145
    Abstract: A method for the removal of solid contaminants which utilizes two rotating mesh screen containers designed to pass the food therethrough while trapping the solid contaminant. The rotation of the first cylindrically-shaped mesh screen causes the food to pass through because of the centrifugal force leaving behind a portion of the solid contaminants. The second mesh or membrane-like placed around the first screen but rotated in the opposite direction is also utilized to trap solid contaminants which are large enough to be trapped by the mesh screen when it is not oriented so as to pass through the screens along its length. Different spacings in mesh and different rotation velocities are utilized to change contaminant screen characteristics.
    Type: Grant
    Filed: July 30, 1997
    Date of Patent: June 22, 1999
    Inventor: Scott Packer
  • Patent number: 5770069
    Abstract: A method and apparatus for sterile separation of a fluid into components, for washing of a material, and for preparing a washed, separated material for refrigerated storage includes rotating the fluid or material in a multi-chambered container to accomplish a centrifuging operation. An apparatus embodying the invention may include an elongated, collapsible container having plural chambers connected in series by necks. The multi-chambered container may be formed of a single flexible bag having plural chambers. Alternately, the container may comprise plural flexible bags, each of which comprises one or more of the chambers of the container. A chamber of the container may be separated into plural sections by partition walls, each of the sections of the chamber being connected to an adjacent chamber by a separate branch of a neck between the chambers.
    Type: Grant
    Filed: February 21, 1997
    Date of Patent: June 23, 1998
    Assignee: Organ, Inc.
    Inventor: Harold T. Meryman
  • Patent number: 5750025
    Abstract: An extracorporeal blood processing system is disclosed which includes a disposable for an apheresis system. The disposable can include a blood processing vessel and a contoured support. The blood processing vessel includes sidewalls to define the vessel and a blood inlet port and a blood component outlet port. The support is provided proximate to the blood component outlet port and exteriorly relative to the fluid-containing volume of the blood processing vessel. The support may be contoured to direct the desired blood component types(s) toward the blood component outlet port and is in an overlapping relation with the exterior surface of the blood processing vessel. The support and part of an adjacent channel wall collectively define a generally funnel-shaped collect well that collects blood components flowing thereby.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 12, 1998
    Assignee: Cobe Laboratories, Inc.
    Inventors: Brian M. Holmes, Jeffrey J. Blakeslee, Victor D. Dolecek
  • Patent number: 5750039
    Abstract: Systems and methods centrifugally separate mono nuclear cells from whole blood in a separation chamber. The systems and methods control the exit hematocrit value of red blood cells separated in the chamber by recirculating a portion of the red blood cells removed from the chamber for mixing whole blood entering the separation chamber. The systems and methods also control the entry hematocrit value of whole blood entering the separation chamber by recirculating a portion of the plasma constituent removed from the separation chamber for mixing whole blood entering the separation chamber.
    Type: Grant
    Filed: November 8, 1996
    Date of Patent: May 12, 1998
    Assignee: Baxter International Inc.
    Inventors: Richard I. Brown, Kyungyoon Min
  • Patent number: 5675905
    Abstract: An apparatus and method for the drying of produce and particularly leafy vegetables. A spin dryer (100) is provided which releasably receives and holds a plurality of manually liftable field baskets (21). A turntable assembly (110) is rotatably mounted to a stationary support structure (105) and operatively coupled to a drive assembly (121). Turntable (110) is adapted to hold a plurality of baskets (21) preferably with the baskets (21) positioned on their sides with their perforated bottom walls (24) facing outwardly and away from the turntable spin axis (14). Produce pieces (22) are preferably stacked in baskets (21) in a parallel vertical orientation with their stems (31) proximate the bottom walls (24) of the baskets (21).
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: October 14, 1997
    Assignee: The Great Northern Equipment Company LLC
    Inventor: John Hougham
  • Patent number: 5578269
    Abstract: A blood analysis system or instrument, generally, including an incubator station, a sample and reagent holding station, a pipette assembly, a centrifuge, an analysis station, and a transport assembly. Generally, the incubation station holds containers while reagents and fluids are being dispensed in those containers, and, if desired, for incubating the containers. The sample and reagent holding station holds samples and a plurality of reagents, and the pipette assembly transfers fluids from that sample and reagent holding station to containers in the incubation station. The centrifuge is provided for centrifuging the container, and the analysis station is provided to analyze the containers optically to identify reactions therein. The transport assembly carries the containers between the incubator station, the centrifuge, and the analysis station.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: November 26, 1996
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Mykola Yaremko, Rosemary Chachowski, Marcel Frischknecht, Gregor Batliner, Linus Flueler, Marco Forster, Martin Gander, Beat Gretener, Walter Imfeld, Hansjoerg Kunz, Martin Kuster, Karl Puchegger
  • Patent number: 5573678
    Abstract: Systems and methods for separating mono nuclear cells from whole blood rotate a separation chamber about a rotational axis. The systems and methods introduce whole blood into a first region of the chamber during its rotation to separate the whole blood into a plasma constituent, red blood cells, and an interface between the red blood cells and the plasma constituent. The interface carries mono nuclear cells. While conveying whole blood into the first region, the systems and methods collect the plasma constituent in the first region, while also collecting the red blood cells in a second region of the chamber spaced from the inlet region. The systems and methods create, while conveying whole blood into the inlet region, a back flow of plasma constituent along the interface from the second region toward the inlet region. This back flow of plasma maintains a high-relative hematocrit in the second region and a low-relative hematocrit in the inlet region.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 12, 1996
    Assignee: Baxter International Inc.
    Inventors: Richard I. Brown, Kyungyoon Min
  • Patent number: 5482626
    Abstract: A liquid sample filtration apparatus includes: a) a module retaining filter elements; b) a filter clamping and fluid injection apparatus positioned relative to the module to engage a filter element thereon, and includes a pair of first and second opposing engageable members to sealing engage a filter element therebetween; c) an inlet tube connected to an opposing engageable member; d) an outlet tube connected to an opposing engageable member; e) a motor to move the module relative to the filter clamping and injection apparatus to register filter elements on the module to the clamping and injection apparatus; and f) a motor associated with the filter clamping and injection apparatus to move the opposing engageable members into substantial sealing fluid communication relative to a filter element on the module.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: January 9, 1996
    Assignee: Lockheed Idaho Technologies Company
    Inventors: Brent C. Lohnes, Terry D. Turner, Kerry M. Klingler, Michael L. Clark
  • Patent number: 5466371
    Abstract: A cytocentrifugation device of the type disclosed by the copending Stokes-Quirante U.S. application Ser. No. 07/788,310 (U.S. Pat. No. 5,252,228 on Oct. 12, 1993) is improved by the provision of elongate, rounded projections on and protruding from the clamping face of the delivery conduit flange at the delivery end of such conduit and the flattening of the otherwise rounded and flange contacting end faces of the clamping arms. Further improvements include a floating mounting for the clamping arms so as to ensure even clamping of the annular area of the absorption pad marginal to the absorption pad opening confronting the cell deposition area of the microscope slide that is otherwise covered by the absorption pad, and the provision for positively, properly aligning the several items to be clamped together during operation of the cytocentrifuge apparatus.
    Type: Grant
    Filed: October 8, 1993
    Date of Patent: November 14, 1995
    Assignee: Wescor, Inc.
    Inventors: Wayne K. Barlow, Carmelo G. Quirante
  • Patent number: 5433850
    Abstract: An adaptor for a honey extractor which is normally manually operable by hand cranking a drive shaft allows it to be operated by a power drill. The adaptor engages the drive shaft axially of the honey extractor after removal of the handle which is used fo manual operation to connect the drive shaft to a power drill. The adaptor is conveniently a socket to engage an end of the drive shaft,the socket having a prong for insertion in the chuck of a power drill.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: July 18, 1995
    Inventor: Thomas P. Murray
  • Patent number: 5380435
    Abstract: A cytocentrifugation device, rotor, and apparatus are improved by providing the device with a plurality of liquid-receiving chambers arranged serially along and opening into an elongate conduit leading to and terminating within a filter-pad-holder so that a filter-pad-prewetting liquid can be passed along such conduit and into a liquid-flow opening of a filter pad held by such holder in advance of passage along said conduit and through such liquid-flow opening in the filter pad of a cell-carrying liquid sample during a centrifugation run of the apparatus. Retention of prewetting liquid in the filter pad around the sample liquid flow helps to prevent loss of cells to the filter pad. Various other structural modifications of the cytocentrifugation device and filter pads used therewith also help to prevent loss of cells to the filter pad.
    Type: Grant
    Filed: August 11, 1993
    Date of Patent: January 10, 1995
    Assignee: Wescor, Inc.
    Inventors: Barry O. Stokes, Carmelo G. Quirante
  • Patent number: 5376267
    Abstract: A cytocentrifugation device, rotor, and apparatus are improved by providing the device with a plurality of liquid-receiving chambers arranged serially along and opening into an elongate conduit leading to and terminating within a filter-pad-holder so that a filter-pad-prewetting liquid can be passed along such conduit and into a liquid-flow opening of a filter pad held by such holder in advance of passage along said conduit and through such liquid-flow opening in the filter pad of a cell-carrying liquid sample during a centrifugation run of the apparatus. Retention of prewetting liquid in the filter pad around the sample liquid flow helps to prevent loss of cells to the filter pad. Various other structural modifications of the cytocentrifugation device and filter pads used therewith also help to prevent loss of cells to the filter pad.
    Type: Grant
    Filed: August 11, 1993
    Date of Patent: December 27, 1994
    Assignee: Wescor, Inc.
    Inventors: Barry O. Stokes, Carmelo G. Quirante
  • Patent number: 5370802
    Abstract: Systems and methods for separating a suspension of plasma and platelets from whole blood rotate a chamber about an axis to create within the chamber a low-G zone radially close to the axis and a high-G zone spaced radially further from the axis than the low-G zone. The systems and methods introduce whole blood into an inlet region of the chamber to initiate separation of red blood cells toward the high-G zone of the inlet region. This creates a strong flow of plasma that moves radially toward the low-G zone of the inlet region and elutes platelets into suspension with it. The systems and methods direct the radial flow of plasma and eluted platelets within the inlet region to a port in the inlet region for transport out of the chamber. The systems and methods also drag the interface into this radial plasma flow, eluting even the largest of platelets into suspension for collection.
    Type: Grant
    Filed: October 22, 1992
    Date of Patent: December 6, 1994
    Assignee: Baxter International Inc.
    Inventor: Richard I. Brown
  • Patent number: 5368171
    Abstract: An apparatus for cleaning substrates used in critical environments with stringent end-product cleanliness requirements in a single process using microwave-energized and centrifuged dense fluids. One or more dense fluids are mixed with one or more chemical or physical agents and are simultaneously subjected to microwave radiation and centrifugal force to remove deeply recessed contaminants from internal and external surfaces of intricately arranged or formulated substrates such as biomaterials, spent activated carbon, elastomerics, surgical aids, or dental implants. Subsequently, cleaned substrates are simultaneously subjected to microwave radiation and centrifugal force under vacuum to remove residual volatile contaminants. Additionally, the cleaned and sterilized substrates are contacted with chemical or physical agents to provide enhanced cleaning and to provide new and improved substrate properties such as increased electrical insulation, conductivity, or biocompatibility.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: November 29, 1994
    Inventor: David P. Jackson
  • Patent number: 5322620
    Abstract: A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.
    Type: Grant
    Filed: August 21, 1991
    Date of Patent: June 21, 1994
    Assignee: Baxter International Inc.
    Inventors: Richard I. Brown, Sidney Smith, David E. Cerny, John T. Foley
  • Patent number: 5256314
    Abstract: Device for measuring off of a volume of a flowable material, comprising a centrifugable reservoir provided with a bottom, side-walls and an entrance opposite the bottom, and an occludable aperture which is spaced between the bottom and entrance both when the aperture is open and when the aperture is closed. The aperture can be closed for collecting an overmeasure of the material in the reservoir pressed towards the bottom thereof during a first centrifuge run and can be opened for discharging the excess volume of the material during a second centrifuge run such that an exactly predetermined volume of the material is retained in the reservoir between the aperture and the bottom.
    Type: Grant
    Filed: December 13, 1991
    Date of Patent: October 26, 1993
    Inventor: Oscar M. J. Driessen
  • Patent number: 5252228
    Abstract: Cytocentrifugation apparatus is improved by providing centrifuging devices with a plurality of liquid-receiving chambers arranged serially along and opening into an elongate conduit leading to and terminating within a filter-pad-holder so that a filter-pad-prewetting liquid can be passed along such conduit and into a liquid-flow opening of a filter pad held by such holder in advance of passage along said conduit and through such liquid-flow opening in the filter pad of a cell-carrying liquid sample during a centrifugation run of the apparatus. Retention of prewetting liquid in the filter pad around the sample liquid flow helps to prevent loss of cells to the filter pad. Various other structural modifications of the cytocentrifugation device and filter pads used therewith also help to prevent loss of cells to the filter pad.
    Type: Grant
    Filed: November 5, 1991
    Date of Patent: October 12, 1993
    Assignee: Wescor, Inc.
    Inventors: Barry O. Stokes, Carmelo G. Quirante
  • Patent number: 5104526
    Abstract: A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: April 14, 1992
    Assignee: Baxter International Inc.
    Inventors: Richard I. Brown, Sidney Smith, David E. Cerny, John T. Foley