Abstract: A blood treatment filter comprising a filter element, an inlet-side flexible container and an outlet-side flexible container, an inlet port, and a tubular outlet port, further comprises: an outlet-side frame sheet disposed between the filter element and the outlet-side flexible container; a first seal portion provided by sealing at least the filter element and the outlet-side frame sheet in a belt-shaped manner; and an annular second seal portion provided to surround the first seal portion, wherein on an outlet side of the filter element, a valley portion is formed at the first seal portion, the outlet port includes a protruding portion that protrudes to an inside of the container, and the protruding portion is provided with an opening at least a part of which overlaps with the first seal portion and which can communicate with a gap region formed by the valley portion.

Abstract: A blood treatment filter comprising a filter element, an inlet-side flexible container and an outlet-side flexible container, an inlet port, and a tubular outlet port, further comprises: an outlet-side frame sheet disposed between the filter element and the outlet-side flexible container; a first seal portion provided by sealing at least the filter element and the outlet-side frame sheet in a belt-shaped manner; and an annular second seal portion provided to surround the first seal portion, wherein on an outlet side of the filter element, a valley portion is formed at the first seal portion, the outlet port includes a protruding portion that protrudes to an inside of the container, and the protruding portion is provided with an opening at least a part of which overlaps with the first seal portion and which can communicate with a gap region formed by the valley portion.

Abstract: Disclosed herein is a single use continuous recovery, flow-through harvest vessel and corresponding method for harvesting culture medium and simultaneously either leaving the microcarrier beads behind in the vessel or flowing microcarrier beads and medium back into a bioreactor.

Abstract: Provided is a membrane module which has a simple and easy structure to restrain its vessel from being increased in costs, and which allows to fabricate the vessel by a simple and easy work, and further to locate an inlet for a fluid, and others at respective predetermined positions of the membrane module.

Abstract: Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments, may include a dialysis machine for transferring dialysate to a patient from a dialysate bag, and a warmer pouch for flowing the dialysate through to heat to a predetermined temperature before flowing into the patient. The dialysate may flow from the dialysate bag through the warmer pouch for pumping into the patient via tubing. A filter may be coupled to the warmer pouch, and the filter may be configured to filter out air content from the dialysate.

Abstract: A venous reservoir including a single inlet line clamp capable of partially or completely restricting blood flow to the venous reservoir. The venous reservoir is provided with a rigid back plate or bracket that can accommodate an inlet line capable of joining to at least one blood inlet port. The rigid back plate or bracket can accommodate a clamp capable of completely or partially closing the inlet line containing both the cardiotomy line and the venous line to manually control the blood flow drained from the patient.

Abstract: In a method for producing a cell concentrate using a cell suspension treatment system including a storage container of a cell suspension, which has a solution inlet port, a circulation outlet port, and a circulation inlet port, a cell suspension treatment device for concentrating the cell suspension by separating liquid from the cell suspension by filtration, the device including a container having a cell suspension introduction port, a cell suspension lead-out port, and a filtrate outlet, which is filled with a hollow fiber separation membrane, a circulation circuit for concentrating the cell suspension while circulating the cell suspension between the storage container and the cell suspension treatment device, a collection container of a cell concentrate obtained by concentration, a collection path for feeding the cell concentrate to the collection container, an injection path for injecting a solution into the solution inlet port of the storage container, and a detecting unit.

Abstract: Methods and systems are provided for a vehicle component cover. In one example, a vehicle component cover may be adapted to conceal vehicle components within an engine compartment, and the cover may include an embedded support structure having a plurality of notched sections. The support structure may deform at the plurality of notched sections to increase an energy absorption characteristic of the vehicle component cover.

Abstract: An air removal device for an intravenous fluid system includes a housing with an inlet for fluid communication with a fluid source, a fluid outlet for fluid communication with a blood vessel of a patient, and an air outlet. The air removal device further includes a disrupting element disposed within the housing in a flow path between the inlet and the fluid outlet, and an air chamber in fluid communication with the air outlet. The disrupting element includes a protrusion extending across the flow path. The flow path includes a first cross-sectional flow area at the inlet, and a second cross-sectional flow area at the protrusion. The second cross-sectional flow area is smaller than the first cross-sectional flow area.

Abstract: A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

Abstract: A syringe for obtaining nano-sized components from a solution includes a barrel having an interior, a needle extending from one end of the barrel, and a plunger received in the interior at an end of the barrel opposite the needle. A filter cartridge is positioned between the needle and the barrel, wherein the filter cartridge maintains at least one membrane having apertures of two distinct size ranges, and wherein operation of the plunger to draw the solution into the barrel allows for retention of nano-sized components of a size between the two distinct size ranges.

Abstract: Multiple embodiments of medical filters are described. For example, this document describes extracorporeal blood filters that have a gradient of filter pore sizes at different portions of the filter element. The gradient of filter pore sizes may enhance the filter's potential for capturing and removing gaseous bubbles that may be present in the blood or other fluid that is flowing through the filter.

Abstract: A surgical access assembly is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath is defined by an open distal end and an open proximal end and includes a hollow body portion therebetween. The obturator is defined by a distal end and a proximal end and the distal end further comprises a tapered distal tip member that terminates in a closed radiused distal tip. The obturator is configured to be received within the outer sheath such that the tapered distal tip member protrudes from the open distal end of the outer sheath when the obturator is in an introducing configuration.

Abstract: A filter for filtering perfusate is integrated with an exterior portion of an organ container. The filter may be used in an apparatus for perfusing an organ. The perfusion apparatus may include an organ container configured to contain an organ, the filter integrated with an exterior portion of the organ container, and another filter. At least the filter integrated with an exterior portion of the organ container may be provided in a sterilized disposable kit.

Abstract: A radioisotope generator system can include a column assembly having a column, an inlet arm, an outlet arm. The column can contain packing material that binds a radioisotope. In addition, the column may define a notch between an open area and a stopper receptacle area in which an opening of the outlet arm is positioned. In some examples, the system includes a Luer lock connection between the outlet arm and a connector tubing. The Luer lock connection can include a male Luer cap and a female Luer cap each comprising tabs configured to line up with or overlap each other so as to indicate when the caps are sufficiently tightened together so as to form a non-leaking lock.

Abstract: Bubble traps for removing bubbles from a stream of liquid and flexible containers comprising such bubble traps are disclosed. The bubble trap includes a containment chamber fluidly coupled to an outlet conduit. At least one grate is disposed between the containment chamber and the outlet conduit. The at least one grate includes a plurality of grate inlets formed in a grate wall and fluidly coupled to the outlet conduit with a plurality of grate conduits such that the containment chamber is fluidly coupled to the outlet conduit. The grate traps bubbles entrained in the stream of liquid flowing from the containment chamber to the outlet conduit in the containment chamber when the bubbles are greater than or equal to a diameter of the grate inlets.

Abstract: The present invention provides novel apparatuses and methods for isolating or recovering a subset of blood cells such as leukocytes and/or circulating tumor cells from blood samples by filtration without changing the intracellular concentration of a therapeutic agent such as an anticancer drug. Contrary to the art, the apparatuses and methods of the present invention advantageously provide cell lysates from recovered cells such as leukocytes and/or circulating tumor cells without substantial dilution of a therapeutic agent such as an anticancer drug.

Abstract: A fluid-storing, filtering, and gas-discharging apparatus (2) comprising a fluid holder (21), a gas detector (23), and a filter (22). The fluid holder (21) has a protruding apex structure and comprises a fluid inlet and a fluid outlet. A gas-discharging pipe in communication with the outside is arranged on the protruding apex of the fluid holder (21). The gas detector (23) is arranged on the gas-discharging pipe. The filter (22) is fixed within the fluid holder (21) and is connected to the fluid outlet. The fluid-storing, filtering, and gas-discharging apparatus (2) uses the fluid holder (21) and the filter (22) to implement the storage and filtration of a working fluid, while at the same time, the fluid holder (21) having the protruding apex structure ensures complete discharging of gases mixed in the working fluid, thus achieves the goals of fluid storage, filtration, and gas discharge, and provides great reliability.

Abstract: Embodiments directed to a degassing device for removing gas bubbles from a liquid drug stream and an ambulatory infusion system are disclosed. The degassing device may comprise an inlet chamber with an inlet opening, an outlet chamber with an outlet opening, and a degassing opening. A hydrophilic membrane and a hydrophobic membrane, wherein the hydrophilic membrane fluidically couples the inlet chamber with the outlet chamber, enabling a transfer of liquid from the inlet chamber to the outlet chamber. The hydrophobic membrane fluidically couples the inlet chamber with the degassing opening, enabling a transfer of gas from the inlet chamber to the degassing opening. The hydrophilic and hydrophobic membranes being joined along a joint to establish a joined membrane, such that a contact line of a liquid-gas phase separation on the joined membrane does not coincide with the joint independent of an orientation of the degassing device with respect to gravity.

Abstract: A medical device includes an elongate metallic hypotube having an open proximal end and an opposed open distal end defining a tubular wall having an open internal diameter and an exterior diameter. The tubular wall has a first flexible portion disposed near the proximal open end and a second portion disposed near the distal open end. The first flexible portion of the hypotube includes a plurality of slots extending through the tubular wall and having a circumferential arc from about 150° to about 300°; and where adjacent slots are axially offset from one and the other from about 30° to about 60°. The medical device may be used as part of an endovascular delivery system.

Abstract: The present invention provides a filter, which includes an enclosure (10) and a filter core (20) mounted inside the enclosure (10). The filter core (20) includes a support (22) and a filtering element (24) entangled with the support (22). The enclosure (10) is of a spherical form and includes: a main body (12), an inlet passage (14) mounted to an upper portion of the main body (12), an outlet passage (16) mounted to a lower portion of the main body (12), and a ventilation tube (18) mounted to a top of the main body (12). The filtering element (24) is set in a spherically-shaped spiral so that the filter core (20) has reduced filtering areas at a top and a bottom ends thereof and an enlarged filtering area at a middle portion. The present invention helps extend the lifespan of the filter. The filter also has a function of gas/liquid separation.

Abstract: A filter assembly is provided. The filter assembly includes a filter cartridge with a containment bag including a vent port and a support housing, including a split lid.

Abstract: A filter cartridge has a shell defining an upper portion with an upper interior volume and a lower portion with a lower interior volume. The cartridge is for use in gravity-fed water treatment systems having an upper untreated supply and a lower filtered container. A hydrophilic porous particulate carbon powder block filter in a polymeric binder is disposed in the cartridge. The filter has a central opening and is open on both ends. The top end of the block is fitted with an air vent tube. The lower end of the block is fitted into a rubber gasket to direct water flow into the lower container. As water flows through the filter cartridge, air is vented through the block filter central opening and out through the vent tube.

Abstract: A fuel filter of an internal combustion engine including a filter housing having a lowermost housing base and a topmost removable housing lid. The filter housing has one raw fuel inlet and one pure fuel outlet. A replaceable annular filter insert mounts there in the filter housing, fuel flowing through it from outside towards inside. The filter subdivides an interior space of the filter housing into a raw zone and a pure zone. A supporting body is arranged in the interior of the annular filter insert, a first flow channel and a second flow channel extending therethrough. The first flow channel connects at one end to the pure zone and at the other end to the pure fuel outlet. The second flow channel connects at one end to the raw zone via a vent throttle or a vent valve and at the other end to a reservoir return in the filter housing.

Abstract: A filter unit including a filter and a housing, in which the filter has an opening on one end side and filters a coating liquid from the outside to the inside of the filter, the housing has, on one end side, an inlet port of the coating liquid, and has, on the other end side, an outlet port of the coating liquid filtered by the filter, the filter is attached to the other end side of the housing so that the opening and the outlet port communicate with each other, and the housing has a release hole through which air is released, the release hole being formed at the other end outside the filter.

Abstract: A top load liquid filter assembly includes a filter lockout mechanism to ensure that the filter base and cover are not connectable unless there is a proper filter cartridge installed therein. The filter system can also include an automatic drain mechanism and a cartridge retention mechanism. One example embodiment further includes an air bleed vent. A filter cartridge usable in the topload liquid filter assembly includes first and second protrusions and cover-gripper members. Methods of use, installing, servicing, and retaining can be practiced.

Abstract: A liquid waste treatment system is described. The system may include a first treatment conduit, a second treatment conduit, and at least one junction pipe disposed there between. In some instances, the system may include an upper junction pipe and a lower junction pipe disposed between a first and a second treatment conduit. In one or more embodiments, the system may be arranged in a substantially linear arrangement, such as a straight trench arrangement or a serial distribution arrangement. The system may reduce the need for additional treatment conduits.

Abstract: A method and device is provided for collecting filterable material to perform assays on a filtration apparatus by applying negative-pressure to the inlet chamber of the filtration apparatus which is independent of negative or positive pressure applied to its fluid path. The negative-pressure applied to the inlet chamber serves to actively aspirate fluid and promote flow into the inlet chamber via the fluid pathway. The negative-pressure applied to the inlet chamber facilitates the use of either negative or positive-pressure based fluid-filtration approaches. Use of the invention improves the functionality and scope of applications that can be performed with enclosed filtration apparatuses.

Abstract: A liquid supply system includes a container containing a liquid, a tank coupled to the container to receive the liquid from the container, and a dispensing mechanism coupled to the tank to receive the liquid to be dispensed. The dispensing mechanism comprises a filter configured to filter the liquid before dispensing. The filter comprises a first gas collection space configured to collect gas accompanying the liquid. The tank is controllably coupled to the first gas collection space of the filter to vent the collected gas from the filter to the tank.

Abstract: A method of injecting fluid into an injection well comprises receiving, by an input device, an input, verifying an authorization to use a filter assembly in response to receiving the input, opening an actuator valve in response to the verifying, actuating a pump in fluid communication with the actuator valve in response to the verifying, receiving a fluid within a filter assembly in response to opening the actuator valve and actuating the pump, wherein the fluid comprises suspended solids, and separating at least a portion of the suspended solids in the fluid within the filter assembly. The pump may be disposed downstream of the filter assembly, and receiving fluid within the filter assembly may comprise drawing fluid into the filter assembly in response to actuating the pump.

Abstract: A filter-deaerator (100) for hydraulic fluid reservoir (102) comprises a chamber (104) that is generally cylindrical and has with a hydraulic fluid inlet (106) at an upper portion (124) thereof that injects hydraulic fluid into the chamber (104) in a direction tangent to an inner wall (108) of the chamber (104). The lower portion (126) of the chamber (104) is configured to be fixed to a hydraulic fluid filter.

Abstract: The disclosed subject matter is directed to a fluid treating system comprising a housing configured with at least one fluid inlet port and at least one fluid outlet port, with at least one fluid treating chamber disposed between and being in flow communication with said at least one fluid inlet port and at least one fluid outlet port, and at least one intermediate chamber disposed between at least one inlet port and at least one of the fluid treating chamber and outlet port. The at least one intermediate chamber is vented to the atmosphere or coupleable to a vacuum source.

Abstract: A solid/fluid separation module and pretreatment apparatus and method enables pretreatment of biomass at high temperature and pressure with the ability to vary residence and processing times.

Abstract: A solid/fluid separation module and pretreatment apparatus and method enables pretreatment of biomass at high temperature and pressure with the ability to vary residence and processing times.

Abstract: A vent assembly is described for use in an extracorporeal fluid unit. A vent structure adjacent to a micro-porous membrane forms the assembly. The vent structure is porous and changes color when the vent structure becomes wet, thereby providing a visual indication that the vent structure has been exposed to liquid.

Abstract: A cartridge top load filter design and filter element useable with the filter are described that allows fluid to be drained from the filter housing, from the exterior of the housing and without first removing the filter element or the housing cover. The draining feature can be manually activated by a knob that is accessible from the exterior of the filter housing adjacent to the removable cover. The draining feature does not require any tools to activate, and provides a “clean service” option of draining fluid before opening the filter housing.

Abstract: The present disclosure generally relates to injection molded thermoplastic single filter media layer and multi-filter media layer filter cartridges that include a novel arrangement of structural features to improve both the quality of the manufacturing process and the integrity of the filter media layer seal and more particularly to a process for manufacturing both single filter media layer and multi-filter media layer filter cartridges and to the single filter media layer and the multi-filter media layer filter cartridges produced thereby and even more particularly to a process for manufacturing a multi-filter media layer filter cartridge without cracking the upper most filter media layer or any filter media layer during the compressing of at least two porous filter media layers between an inlet and an outlet while insuring an effective seal and the multi-filter media layer filter cartridges produced thereby and, yet, more particularly, to single filter media layer and the multi-filter media layer filter car

Abstract: Devices, methods, and systems for obtaining one or more biological fluid components, and reducing red blood cell contamination, using a back-flushable filter device, are disclosed.

Abstract: A filter capsule has a filter housing which, on at least one end face, has an end cap with an air release valve. A protective wall is formed on the end cap at a distance from the air release valve and protrudes beyond the air release valve.

Abstract: An apparatus and a method for filling a container containing a dry powdered salt concentrate for use in dialysis with purified fluid and removing the trapped air or gases generated during the filling of the container, while maintaining the required fluid level in the container and without the need for evacuating gases from the container prior to filling.

Abstract: Embodiments of the invention provide venting and filtration systems with a membrane that is permeable to gas and substantially impermeable liquid. The systems can remove a gas from a liquid entrained with gas. The systems can include a reservoir in fluid communication with the membrane and a liquid outlet. The membrane can help prevent the gas from reaching the liquid outlet.

Abstract: A device for separating blood into individual components and/or groups of components, in the form of a sterilizable system includes a filter arrangement forming inlet and outlet chambers using filter elements arranged therein, and respective receptacles for cellular blood components and for blood plasma. The inlet chamber can be connected to the blood source via a line on the inlet side to conduct the blood and is connected, on the outlet side, to the cellular blood components receptacle. The outlet chamber is connected to the blood plasma receptacle via a line on the outlet side. Thermal sterilization is used to sterilize the device by opening a respective line into the inlet-side line of the inlet chamber, into the inlet chamber and the outlet-side line of the outlet chamber, or into the outlet chamber, the line being connected to the exterior via a hydrophobic or hydrophilic filter.

Abstract: A system and method for concentrating samples. The system can include a first container adapted to contain a sample. The first container can include a first portion and a second portion adapted to be removably coupled to the first portion. The system can further include a second container comprising the second portion and a third portion adapted to be removably coupled to the second portion. The method can include centrifuging the first container in a first orientation toward the second portion of the first container; retaining a concentrate of the sample in the second portion of the first container; and centrifuging the second container in a second orientation toward the third portion of the second container, such that the concentrate retained in the second portion is moved into the third portion of the second container, the second orientation being different from the first orientation.

Abstract: A filter device and a method for the filtration of beer, where, for an improved and simplified filtration, the filter includes a nonfiltrate chamber having a nonfiltrate inlet and a nonfiltrate outlet, wherein the nonfiltrate flows into the nonfiltrate chamber substantially tangentially to the walls thereof, and the bottom of the nonfiltrate chamber is constructed at least partially as a filter. The filter also includes a filtrate chamber underneath the bottom, and a filtrate outlet.

Abstract: A device for continuously, periodically monitoring water for microbial germs, comprising a reactor and at least one reagent feed line into the reactor and at least one metering device for reagents as well as at least one measuring device for detecting the presence of microorganisms, wherein the reactor comprises a reactor chamber and a filtrate chamber, which is separated from said reactor chamber by means of a filter, a water feed line as well as a reagent feed line empty into the reactor chamber and at least one water discharge line leads out of the filtrate chamber, and a controller is set up to use pump/valve means to lead a predefinable quantity of water into the reactor chamber and through the filter as well as to introduce a predefinable quantity of reagent into the reactor chamber.

Abstract: An apparatus for de-aering, oxygenating and controlling a temperature of blood in an extracorporeal blood circuit. The apparatus includes a housing, a manifold body, a heat exchanger, and an oxygenator. A blood inlet tangentially directs blood into a first chamber of the housing. The manifold body is disposed in a second chamber, and includes a core and a plurality of vanes that define channels. The heat exchanger is arranged around the manifold body, and the oxygenator around the heat exchanger. The channels are open to the heat exchanger. An established blood flow path includes rotational flow within the first chamber to separate air from the blood, generally longitudinal flow from the first chamber and along the channels, and generally radial flow through the heat exchanger and the oxygenator. With this construction, gross air removal occurs prior to the blood passing through the heat exchanger and oxygenator.

Abstract: A top load liquid filter assembly includes a filter lockout mechanism to ensure that the filter base and cover are not connectable unless there is a proper filter cartridge installed therein. The filter system can also include an automatic drain mechanism and a cartridge retention mechanism. One example embodiment further includes an air bleed vent. A filter cartridge usable in the topload liquid filter assembly includes first and second protrusions and cover-gripper members. Methods of use, installing, servicing, and retaining can be practiced.

Abstract: A filter assembly is provided. The filter assembly includes a filter cartridge with a containment bag including a vent port and a support housing, including a split lid.

Abstract: The invention relates to a filtration device including a flat filter module and a base housing, on which the flat filter module is placed. A wall of the base housing includes a polymer cellular lightweight construction material, or a fiber composite material.

Abstract: A filter assembly for filtering water from an external source, the filter assembly having a manifold assembly and a filter cartridge. The filter cartridge includes a cartridge engagement means while the manifold includes a manifold engagement means. The cartridge engagement means and manifold engagement means cooperatively interfacing for removable attachment of the filter cartridge to the manifold assembly. The cartridge engagement means and manifold engagement means oriented in a retaining relation during removal of the cartridge filter from the manifold assembly such that any entrained pressure within the cartridge filter is vented while the cartridge engagement means and manifold engagement means are in the retaining relation.