Hollow Fiber Or Cylinder Patents (Class 210/500.23)
  • Patent number: 10767280
    Abstract: High permeability curly fibers with enhanced fiber strength are produced by mercerizing cellulosic fibers. The fibers have relatively high values for curl, kink level, wet tensile strength, and bulk density when compared with current fibers. The disclosed fibers can be used in a wide range of applications including paper products such as filters.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 8, 2020
    Assignee: GP CELLULOSE GMBH
    Inventors: Alan Jeffrey Campbell, Sonja McNeil Fields, Danny R. Moore, Stephen Skirius
  • Patent number: 10751671
    Abstract: The porous hollow fiber membrane of the present invention contains a thermoplastic resin, and includes a surface having a surface porosity of 32 to 60% and a fine pore diameter of 300 nm or less, and has a compressive strength of 0.7 MPa or more. The porous hollow fiber membrane of the present invention may include at least two layers, and in this case, the surface of one layer has a thickness of backbone of 0.3 to 20 ?m and a fine pore diameter of 0.3 to 10 ?m, and the surface of the other layer has a surface porosity of 32 to 60% and a fine pore diameter of 0.05 to 0.3 ?m.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: August 25, 2020
    Assignee: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Daisuke Okamura, Yuki Miki, Masatoshi Hashino
  • Patent number: 10717835
    Abstract: A block copolymer, an ion-exchange membrane including the block copolymer and a method of preparing the block copolymer are provided. The block copolymer may include a hydrophobic repeating unit and a hydrophilic repeating unit.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: July 21, 2020
    Assignee: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Byungchan Bae, Sung-Dae Yim, Chang-Soo Kim, Won-Yong Lee, Gu-Gon Park, Tae-Hyun Yang, Seok-Hee Park, Minjin Kim, Young-Jun Sohn, Seung-Gon Kim, Dong Won Shin, Adam Febriy-Anto Nugraha
  • Patent number: 10709612
    Abstract: Odor control articles (10) including hydrophobic polymers of intrinsic porosity (HPIM) and their use in personal care products and hygienic products is disclosed. The odor control article (10) includes a HPIM and a colorant. The odor control article (10) may be applied to a substrate (11), and more specifically to a liquid absorbent member (30), to form an odor-absorbing member (20). The substrate (11) may absorb liquid. The odor-absorbing member (20) may be placed in such products as diapers (200), incontinence pads (60) and refrigerator pads. A method of making an odor control suspension with HPIMs including the use of surfactants is also disclosed. The odor control suspension may also be applied to a substrate (11).
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: July 14, 2020
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Xuedong Song, Davis Dang H. Nhan, John Gavin MacDonald, Richard Arnold Borders
  • Patent number: 10684220
    Abstract: A process of in-situ detection of hollow fiber formation includes immersing a plurality of individual glass fibers in an index-matching material. The index-matching material has a first refractive index that substantially matches a second refractive index of the glass fibers. The process also includes exposing the individual glass fibers to a light source during immersion in the index-matching material. The process further includes utilizing one or more optical components to collect optical data for the individual glass fibers during immersion in the index-matching material. The process also includes determining, based on the optical data, that a particular glass fiber of the plurality of individual glass fibers includes a hollow fiber.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: June 16, 2020
    Assignee: International Business Machines Corporation
    Inventors: Eric J. Campbell, Bruce J. Chamberlin, Sarah K. Czaplewski, Scott B. King, Joseph Kuczynski
  • Patent number: 10661230
    Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: May 26, 2020
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Bernd Krause, Markus Storr, Philipp Herbst, Arnd Wochner, Adriana Boschetti-De-Fierro, Manuel Voigt, Carina Zweigart, Joachim Loercher, Reinhold Buck, Heinrich Behr, Werner Beck
  • Patent number: 10661231
    Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: May 26, 2020
    Assignee: GAMBRO LUNDIA AB
    Inventors: Adriana Boschetti-De-Fierro, Manuel Voigt, Bernd Krause, Markus Hornung, Markus Storr, Heinrich Behr, Werner Beck, Carina Zweigart, Reinhold Buck, Philipp Herbst, Joachim Loercher, Arnd Wochner
  • Patent number: 10639595
    Abstract: A problem to be solved by the present invention is to provide a separation membrane having excellent separation performance, having high membrane strength and high permeation performance, and mainly including a cellulose-based resin. The present invention is concerned with a separation membrane including a cellulose ester, having, in the interior thereof, voids each having a specified structure, and having a tensile elasticity of 1,000 to 6,500 MPa.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: May 5, 2020
    Assignee: TORAY INDUSTRIES, INC.
    Inventors: Koichi Takada, Gohei Yamamura, Ryuichiro Hiranabe, Hiroki Tomioka
  • Patent number: 10604625
    Abstract: A poly(phenylene ether) can be prepared by a method that includes reacting 2,6-dimethylphenol in the presence of toluene, oxygen, copper ion, bromide ion, and N,N?-di-tert-butylethylenediamine to form a poly(phenylene ether). The mole ratio of 2,6-dimethylphenol to copper ion is 160:1 to 300:1, the mole ratio of N,N?-di-tert-butylethylenediamine to copper ion is 1.5:1 to 3:1, and the mole ratio of atomic oxygen to 2,6-dimethylphenol is 0.9:1 to 1.5:1. The process can produce poly(phenylene ether) having a high molecular weight and a high incorporated amine content.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: March 31, 2020
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventor: Madhav Ghanta
  • Patent number: 10589229
    Abstract: A central tube assembly for a filter cartridge and a manufacturing method for the central tube assembly are provided. The central tube assembly includes a first half-tube defines a first flow passage, and having a first water inlet at an end thereof and a water output hole in a side wall thereof a filtering membrane bent to form a first membrane layer and a second membrane layer, the first half-tube being disposed between the first membrane layer and the second membrane layer; an input-water filtering net connected to the first half-tube and disposed between the first membrane layer and the second membrane layer a second half-tube disposed outside of a bending of the filtering membrane, defining a second flow passage, and having a water input hole in a side wall thereof and a first water outlet at an end thereof and a produced-water filtering net.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: March 17, 2020
    Inventors: Guodong Song, Xuegang Cai, Peng Gui
  • Patent number: 10578551
    Abstract: A process of in-situ detection of hollow fiber formation includes immersing a plurality of individual glass fibers in an index-matching material. The index-matching material has a first refractive index that substantially matches a second refractive index of the glass fibers. The process also includes exposing the individual glass fibers to a light source during immersion in the index-matching material. The process further includes utilizing one or more optical components to collect optical data for the individual glass fibers during immersion in the index-matching material. The process also includes determining, based on the optical data, that a particular glass fiber of the plurality of individual glass fibers includes a hollow fiber.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: March 3, 2020
    Assignee: International Business Machines Corporation
    Inventors: Eric J. Campbell, Bruce J. Chamberlin, Sarah K. Czaplewski, Scott B. King, Joseph Kuczynski
  • Patent number: 10478782
    Abstract: Problems that the invention is to solve is to provide a composite hollow fiber membrane being excellent in separation performance and permeation performance, having high membrane strength, and capable of being easily produced, and a method for producing the same. The present invention relates to a composite hollow fiber membrane including at least a layer (A) and a layer (B), in which the composite hollow fiber membrane has an outer diameter of 20 to 350 ?m and an inner diameter of 14 to 250 ?m, the tensile modulus of the composite hollow fiber membrane is from 1,000 to 6,500 MPa, the layer (A) contains a cellulose ester, the thickness of the layer (A) is from 0.01 to 5 ?m, and the open pore ratio HA of the layer (A) and the open pore ratio HB of the layer (B) satisfy HA<HB.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: November 19, 2019
    Assignee: TORAY INDUSTRIES, INC.
    Inventors: Gohei Yamamura, Koichi Takada, Ryuichiro Hiranabe, Hiroki Tomioka
  • Patent number: 10458979
    Abstract: The present invention relates to an artificial cell membrane system comprising at least one membrane protein carrier associated with at least one membrane protein, wherein the at least one membrane protein carrier comprises or consists of a polymeric vesicle or a polymeric planar structure, and a solid support freely suspended in a fluid medium, wherein the at least one membrane protein carrier is attached to a surface of the solid support. A method of forming the artificial cell membrane system, and use of the artificial cell membrane system as a reagent are also provided.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: October 29, 2019
    Assignee: Agency for Science, Technology and Research
    Inventors: Jinting Cheng, Madhavan Nallani
  • Patent number: 10421046
    Abstract: An method of making a porous asymmetric membrane involves dissolving a poly(phenylene ether), poly(phenylene ether) copolymer, polyethersulfone, polysulfone, polyphenylsulfone, polyimide, polyetherimide, polyvinylidene fluoride, or a combination thereof in a water-miscible polar aprotic solvent to provide a membrane-forming composition; and phase-inverting the membrane-forming composition in a first non-solvent composition composed of water, a water-miscible polar aprotic solvent, or a mixture thereof, and a polymer additive dissolved in the first non-solvent composition. The method can be a method of making a hollow fiber by coextrusion through a spinneret having an annulus and a bore, including coextruding the membrane-forming composition through the annulus, and the first non-solvent composition through the bore, into a second non-solvent composition composed of water, a water-miscible polar aprotic solvent, or a mixture thereof to form the hollow fiber.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: September 24, 2019
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Albin Peter Berzinis, Pooja Bajaj, Rachel Elizabeth Halbfinger
  • Patent number: 10406487
    Abstract: Provided is a vinylidene fluoride porous hollow fiber membrane excellent in fouling resistance due to reduced organic substance absorbance, preferably having preferable pore structures to enable to have high permeability, high fractionation performance, and good process controllability. The membrane includes a vinylidene fluoride resin and 0.5 to 10% by weight of a hydrophilic resin, having a ratio Pi/Po of 2.5 to 50 where Pi and Po denote an average pore size on inner surface and an average pore size on outer surface, respectively, and having a pure water permeation rate satisfying the following formula: (FLUXd/FLUXw)×100?40.0 wherein FLUXd represents a pure water permeation rate (L/m2/hr/98 kPa) of the hollow fiber membrane in a dry state, and FLUXw represents a pure water permeation rate (L/m2/hr/98 kPa) of the hollow fiber membrane in a wet state.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: September 10, 2019
    Assignee: KURARAY CO., LTD.
    Inventors: Arata Ishiodori, Kensaku Komatsu, Youhei Yabuno
  • Patent number: 10352835
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: July 16, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, Jr.
  • Patent number: 10322220
    Abstract: A method for extracorporeal blood treatment using a medical device including at least a dialyzer device, with the following steps: start of blood treatment by means of hemodialysis on the basis of default values for the hemodialysis; determination of current values or ratios of at least one blood flow, an ultrafiltration quantity, a substitution quantity or a type of substitution; recording of a therapy progress on the basis of an output signal of a sensor means; determination of a time of formation of a secondary membrane on the dialyzer by determination of a cross rate in the dialyzer device; change from the hemodialysis to a hemodiafiltration with post-dilution after a predetermined period of time has elapsed; and regulation of the substitution quantity during hemodiafiltration with post-dilution. Corresponding tools for carrying out the method are arranged in a device for extracorporeal blood treatment.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: June 18, 2019
    Assignee: B. Braun Avitum AG
    Inventor: Heiko Riemenschneider
  • Patent number: 10319973
    Abstract: To afford a nonaqueous electrolyte secondary battery separator that is not easily curled, a laminated body of the present invention includes: a porous base material containing a polyolefin-based resin as a main component; and a porous layer on at least one surface of the porous base material, the porous layer containing a polyvinylidene fluoride-based resin, the porous film having a lightness (L*) of not less than 83 and not more than 95 and a white index (WI) of not less than 85 and not more than 98, the polyvinylidene fluoride-based resin containing crystal form ? in an amount of not less than 34 mol % with respect to 100 mol % of a total amount of the crystal form ? and crystal form ? contained in the polyvinylidene fluoride-based resin.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: June 11, 2019
    Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Toshihiko Ogata, Junji Suzuki, Chikara Murakami
  • Patent number: 10307513
    Abstract: Provided herein are methods of making a biomimetic hydrogel scaffold comprising a polycation and a polyanion. Also provided are anisotropic biomimetic hydrogel scaffold compositions suitable for use in tissue growth, including bone, muscle, and nerve growth an optionally comprising a carbon allotrope such as graphene. Also provided are methods of producing tissue comprising growing tissue on the biomimetic hydrogel scaffold comprising a polycation and a polyanion.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: June 4, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventor: Shilpa Sant
  • Patent number: 10301585
    Abstract: A filter assembly for separating microcarriers from a fluid medium includes a collapsible container bounding a sterile compartment adapted to hold a fluid. An inlet port is attached to the container through which fluid flows into the compartment. An outlet port is attached to the container through which fluid flows out of the compartment. A filter is disposed within the compartment, the filter dividing the compartment into an inlet chamber that is fluidly coupled with the inlet port and an outlet chamber that is fluidly coupled with the outlet port, the filter allowing a medium to pass therethrough but preventing microcarriers disposed in the medium from passing therethrough.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: May 28, 2019
    Assignee: Life Technologies Corporation
    Inventors: Jeremy K. Larsen, Jon Q. Coleman, David S. Rowley
  • Patent number: 10265453
    Abstract: An artificial, extracorporeal system for liver replacement and/or assistance, comprises a liver dialysis device for conducting hemodialysis on a patient suffering from liver failure. The liver dialysis device comprises a first standard hollow fiber membrane dialyzer which does not allow passage of an essential amount of albumin over the membrane wall and which is perfused with the patient's blood, and a second hollow fiber membrane dialyzer which allows the passage of essential but defined amounts of albumin over the membrane wall and which receives the blood of the first standard hemodialyzer. The filtrate space is closed off from the lumen space of the hollow fibers and is populated by adsorbent material which may comprise one or more different adsorbents.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: April 23, 2019
    Assignee: GAMBRO LUNDIA A.B.
    Inventors: Ralf Flieg, Stephan Aldinger, Markus Storr, Bernd Krause
  • Patent number: 10265663
    Abstract: The present invention relates to a method of forming a polyarylene ether sulfone polymer by converting a reaction mixture (RG) comprising a dihalogen component (A1), a dihydroxy component (B1) and potassium carbonate (C1) having a volume-average particle size of <25 ?m. The present invention further relates to the polyarylene ether sulfone polymers obtainable by said method, to products obtainable from said polyarylene ether sulfone polymer and to membranes formed from said polyarylene ether sulfone polymer.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: April 23, 2019
    Assignee: BASF SE
    Inventors: Martin Weber, Christian Maletzko, Joerg Erbes, Tobias Kortekamp, Bastiaan Bram Pieter Staal, Thomas Heil
  • Patent number: 10265452
    Abstract: The present technology provides microfabricated filtration devices, methods of making such devices, and uses for microfabricated filtration devices. The devices may allow diffusion to occur between two fluids with improved transport resistance characteristics as compared to conventional filtration devices. The devices may include a compound structure that includes a porous membrane overlying a support structure. The support structure may define a cavity and a plurality of recesses formed in a way that can allow modified convective flow of a first fluid to provide improved diffusive transport between the first fluid and a second fluid through the membrane.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: April 23, 2019
    Assignee: The Regents of the University of California
    Inventors: Rishi Kant, Shuvo Roy, Benjamin Chui, Kenneth G. Goldman
  • Patent number: 10252222
    Abstract: A hollow fiber type semipermeable membrane which achieves both water permeability and selectivity in high level and performs efficient treatment using small membrane area utilizing the concentration difference from high concentration liquid having high osmotic pressure. The hollow fiber type semipermeable membrane is characterized in that, when an aqueous solution of 25° C. having NaCl concentration of 35 g/L and pressure of 1.0 MPa is flown into an outer side of the hollow fiber type semipermeable membrane having length of about 70 cm while freshwater of 25° C. having NaCl concentration of 0 g/L is flown into an inner side of one open end of the hollow fiber type semipermeable membrane and discharged from another open end at 10 kPa or less, the permeation flow rate is 30 to 70 L/m2/day. An inner diameter thereof is 50 to 200 ?m; and the hollow ratio thereof is 24 to 42%.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: April 9, 2019
    Assignee: TOYOBO CO., LTD.
    Inventors: Michiko Shimizu, Toshiyuki Yagi, Shinobu Tokimi
  • Patent number: 10232320
    Abstract: The present invention provides a hollow-fiber membrane blood purification device obtained by filling a container with a hollow-fiber membrane, in which the hollow-fiber membrane contains a hydrophobic polymer, a hydrophilic polymer and a lipid-soluble substance; the amount of the lipid-soluble substance on the inner surface of the hollow-fiber membrane is 10 mg/m2 or more and 300 mg/m2 or less; and the oxygen transmission rate of the container is 1.8×10?10 cm3·cm/(cm2·s·cmHg) or less.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: March 19, 2019
    Assignee: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Yosuke Hata, Chiharu Kawano, Ryoko Hori
  • Patent number: 10201648
    Abstract: The present disclosure relates to a filter module for a medical fluid delivery system capable of removing cytokine inducing substances (CIS) from a medical fluid.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: February 12, 2019
    Assignee: GAMBRO LUNDIA AB
    Inventors: Eugenio Lombardo, Stefano Ganzerli, Matteo Manfredini, Marco Morini
  • Patent number: 10159943
    Abstract: The present invention provides a carbon membrane for fluid separation with which a high-pressure fluid can be separated and purified and which has excellent pressure resistance and is less apt to be damaged. The present invention relates to a carbon membrane for fluid separation, including: a core layer which has a co-continuous porous structure; and a skin layer which has substantially no co-continuous porous structure and is formed around the core layer.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: December 25, 2018
    Assignee: Toray Industries, Inc.
    Inventors: Kosaku Takeuchi, Kentaro Tanaka, Takaaki Mihara, Tomoyuki Horiguchi
  • Patent number: 10112000
    Abstract: The present invention relates to a method for reducing a ?-amyloid concentration in blood. Specifically, the present invention relates to a method for reducing a ?-amyloid concentration in blood, comprising the steps of; removing blood out of a body, passing the blood that is removed through a hollow fiber membrane, and returning the blood that is passed through into the body, wherein the blood containing a ?-amyloid-albumin complex is passed through the hollow fiber membrane to allow ?-amyloid to adsorb to the hollow fiber membrane so that the ?-amyloid concentration in blood is reduced.
    Type: Grant
    Filed: July 8, 2011
    Date of Patent: October 30, 2018
    Assignees: ASAHI KASEI MEDICAL CO., LTD., SCHOOL JURIDICAL PERSON FUJITA EDUCATIONAL INSTITUTION
    Inventors: Nobuya Kitaguchi, Kazunori Kawaguchi
  • Patent number: 10046283
    Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 14, 2018
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Takahiko Hariyama, Yasuharu Takaku, Hiroshi Suzuki, Masatsugu Shimomura, Daisuke Ishii, Isao Ohta, Yoshinori Muranaka
  • Patent number: 10010504
    Abstract: The present invention relates to compositions and methods for treatment of proliferative disease. In specific aspects, the present invention relates to compositions including celecoxib and plumbagin in combination; methods for treatment of a proliferative disease including administration of celecoxib and plumbagin in a subject in need thereof; and particularly methods for treatment of skin cancer including administration of celecoxib and plumbagin in a subject in need thereof.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 3, 2018
    Assignee: The Penn State Research Foundation
    Inventors: Gavin P. Robertson, Chandagalu D. Raghavendra Gowda, Arati K. Sharma, Gregory Kardos, Sanjay Singh
  • Patent number: 10005044
    Abstract: The invention relates to a virus filter membrane which can be used for the removal of virus particles including parvovirus. The invention further relates to a method for producing the membrane. The membrane comprises polyacrylonitrile and polyvinylpyrrolidone.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: June 26, 2018
    Assignee: GAMBRO LUNDIA AB
    Inventors: Markus Hornung, Bernd Krause, Johannes Geckeler, Ferdinand Schweiger, Szymon Dutczak, Simon Beiter
  • Patent number: 10006842
    Abstract: Provided is a simple method for producing a cell concentrate (other than human blood) in a short time with neither loss of cells nor an excessive burden on cells. Included is a method for producing a cell concentrate using an inside-out filtration system for processing a cell suspension, the system including: a cell suspension inlet port; a filtrate outlet port; a cell suspension outlet port; and hollow fiber separation membranes provided between the cell suspension inlet port and the cell suspension outlet port, wherein the membranes have a total cross-sectional area of 0.5-1.5 cm2, the membranes have an inside membrane area of 0.2 m2 or less, the suspension is flowed inside the membranes at a linear velocity of 500-1200 cm/min, and the quotient of the division of the initial filtrate flow rate from the filtrate outlet port by the flow rate into the cell suspension inlet port is 0.4-0.7.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: June 26, 2018
    Assignee: KANEKA CORPORATION
    Inventor: Shuhei Taniguchi
  • Patent number: 9968888
    Abstract: The present invention is directed to a method of sealing the free end of a hollow fiber membrane for use in a single header filtration module by dipping the end of the membrane into a low-viscosity light-curable adhesive and curing the adhesive. The invention further encompasses the resulting sealed hollow fiber membrane with a diameter that is only slightly larger than the diameter of the unsealed membrane.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: May 15, 2018
    Assignee: Koch Membrane Systems, Inc.
    Inventors: Taylour Johnson, David Colby
  • Patent number: 9958364
    Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: May 1, 2018
    Assignee: 3M Innovative Properties Company
    Inventors: Jerald K. Rasmussen, Catherine A. Bothof, George W. Griesgraber, Semra Colak Atan, James I. Hembre, Robert T. Fitzsimons, Jr.
  • Patent number: 9951170
    Abstract: A sulfonated polyphosphazene copolymer proton exchange membrane material, and a method for preparing such membrane includes a macromolecule initiator as bromo polyphosphazene is subjected to atom transfer radical polymerization with styrene, yielding a graft copolymer, which is hydrazinolyzed with hydrazine hydrate resulting in a copolymer including a hydroxyl group. The copolymer is reacted with 1,4-butane sultone to yield a sulfonated copolymer finally. The polymer is cross-linked with 2,6-di(hydroxymethyl)-4-methyl phenol (BHMP) as a cross linking agent in the presence of methyl sulfonic acid, yielding cross-linked proton exchange membrane. Such cross-linked graft copolymer membrane has high proton conductivity, low methanol hindrance, and low cost, and has ideal effect when applied in fuel cells as proton exchange membrane material.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: April 24, 2018
    Inventor: Hulin Xu
  • Patent number: 9919250
    Abstract: A filter for the separation of oil and water from oil-water mixtures comprising a porous filter media, wherein the porous filter media has a zwitterionic polymer grafted or coated thereon. The zwitterionic polymers can be formed from zwitterionic monomers, the zwitterionic polymers having positive and negative charges in series on the same side chain; zwitterionic polymers formed from a mixture of cationic and anionic monomers, the zwitterionic polymers having positive and negative charges on two different side chains; and zwitterionic polymers formed from monomers with cationic-anionic pairs, the zwitterionic polymers having positive and negative charges in parallel on the same side chain.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: March 20, 2018
    Assignee: THE UNIVERSITY OF AKRON
    Inventor: Lingyun Liu
  • Patent number: 9902939
    Abstract: A device for culturing, storing and expanding adherent renal cells. The device permits the adhesion and proliferation of the cells and the surface characteristics of the membrane material used in said device further permit the cellular matrix components (EMC). A method for expanding adherent renal cells and methods of using particular membranes for culturing, storing and expanding adherent renal cells. The membranes comprise a copolymer of acrylonitrile and sodium methallyl sulfonate as well as polyethylenimine.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: February 27, 2018
    Assignee: Gambro Lundia AB
    Inventors: David Luttropp, Markus Neubauer, Helmut Geiger, Juergen Bereiter-Hahn, Patrick Baer, Reinhold Deppisch, Doris Deppisch
  • Patent number: 9889410
    Abstract: A tubular braid, a hollow fiber membrane using the same, and a manufacturing method thereof. A hollow fiber membrane can maximize or increase adhesion between a polymer coating film and a tubular braid; significantly reduce degradation of film properties caused by non-uniform coating, that is, reduce leakage; obtain a higher percent rejection; and achieve high water permeability since the hollow fiber membrane has a larger inner diameter.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: February 13, 2018
    Assignee: LOTTE CHEMICAL CORPORATION
    Inventors: Chang Min Seo, Gyeong Mo Lee, Myoung Won Park
  • Patent number: 9863875
    Abstract: A process of in-situ detection of hollow fiber formation includes immersing a plurality of individual glass fibers in an index-matching material. The index-matching material has a first refractive index that substantially matches a second refractive index of the glass fibers. The process also includes exposing the individual glass fibers to a light source during immersion in the index-matching material. The process further includes utilizing one or more optical components to collect optical data for the individual glass fibers during immersion in the index-matching material. The process also includes determining, based on the optical data, that a particular glass fiber of the plurality of individual glass fibers includes a hollow fiber.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: January 9, 2018
    Assignee: International Business Machines Corporation
    Inventors: Eric J. Campbell, Bruce J. Chamberlin, Sarah K. Czaplewski, Scott B. King, Joseph Kuczynski
  • Patent number: 9849427
    Abstract: An object of the present invention is to provide a hollow fiber membrane with enhanced phosphorus-removing performance without impairing antithrombogenicity in order to inhibit in vivo accumulation of phosphate ions in living body that might cause bone metabolism disorders. The present inventors have found that a hollow fiber membrane having a specific membrane structure and a specific membrane composition possesses a very useful range for inner surface charges of the membrane. More particularly, the inventors have discovered that the above object can be achieved in a limited range in which the zeta potential on the inner surface of a hollow fiber membrane measured under given certain conditions is greater than ?3.0 mV but less than 0 mV. This finding has led to the completion of the present invention.
    Type: Grant
    Filed: November 17, 2004
    Date of Patent: December 26, 2017
    Assignee: ASAHI KASEI MEDICAL CO., LTD.
    Inventors: Mariko Kuroda, Masaya Fuke, Masaki Katou
  • Patent number: 9844756
    Abstract: Provided herein are filtration membranes, method of manufacturing said membranes and use of such membranes for the removal of substances from fluids or substances.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: December 19, 2017
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Chad D. Vecitis, Jose Carlos Mierzwa
  • Patent number: 9845380
    Abstract: Disclosed are compositions and methods of preparing ionic polyimides. Also disclosed are methods to tune the properties of the ionic polyimide by designing the components of the ionic polyimide. Additionally, disclosed herein is a composition comprising an ionic polyimide. Also disclosed herein is a composition comprising an ionic polyimide and an ionic liquid. The disclosed compositions can be utilized to capture gases.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: December 19, 2017
    Assignee: The Board of Trustees of The University of Alabama
    Inventors: Jason Edward Bara, Matthew S. Shannon, John David Roveda, Jr., David A. Wallace, Max Simon Mittenthal
  • Patent number: 9827532
    Abstract: A pervaporation membrane may be an acid-resistant polybenzidimazole (PBI) membrane. The acid-resistant PBI membrane may be a PBI membrane chemically modified by a process selected from the group consisting of sulfonation, phosphonation, cross-linking, N-substitution, and/or combinations thereof. The membrane may be thermally stabilized. A method for the dehydration of an acid material may include the steps of: contacting an acidic aqueous solution with a membrane of an acid-resistant polybenzidimazole; taking away a permeate stream rich in water; and taking away a concentrate steam rich in the acid material. The acidic aqueous solution may be acetic acid.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: November 28, 2017
    Assignee: PBI Performance Products, Inc.
    Inventors: Yan Wang, Michael Gruender, Tai-shung Chung
  • Patent number: 9821105
    Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. The nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The montmorillonite, the bentonite, and the other clays may be used in wearable systems, such as a wearable peritoneal dialysis system, in which a dialysis fluid is circulated through a filter with the nanoclay sorbents. Waste products are absorbed by the montmorillonite, the bentonite, and the other clays and the dialysis fluid is recycled to a patient's peritoneum. Using an ion-exchange capability of the montmorillonite, the bentonite, and the other clays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: November 21, 2017
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Rosa H. Yeh, Wei Xie, Hsinjin E. Yang, Michael T. K. Ling, Ying-Cheng Lo
  • Patent number: 9815031
    Abstract: A separation module that includes a porous membrane, where the porous membrane includes a poly(phenylene ether) copolymer containing 10 to 40 mole percent repeat units derived from 2-methyl-6-phenylphenol and 60 to 90 mole percent repeat units derived from 2,6-dimethylphenol; and a block copolymer containing backbone or pendant blocks of poly(C2-4 alkylene oxide). The separation module can be used in devices for wastewater treatment, water purification, desalination, separating water-insoluble oil from oil-containing wastewater, membrane distillation, sugar purification, protein concentration, enzyme recovery, dialysis, liver dialysis, or blood oxygenation.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: November 14, 2017
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Albin Peter Berzinis, Joris de Grooth, Johannes de Brouwer, Meijuan Zhou, Pooja Bajaj, Rachel Elizabeth Halbfinger, Kristi Jean Narang
  • Patent number: 9795927
    Abstract: A carbon molecular sieve (CMS) membrane is made by pyrolyzing a polymeric precursor membrane in a pyrolysis atmosphere containing a sulfur-containing compound.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: October 24, 2017
    Assignee: L'Air Liquide Société Anonyme Pour L'Étude Et L'Exploitation Des Procedes Georges
    Inventors: Henri Chevrel, Benjamin J. Jurcik, Jr., Philippe A. Coignet, Raja Swaidan, Dean W. Kratzer
  • Patent number: 9795932
    Abstract: The purpose of the present invention is to provide a porous hollow fiber membrane that can efficiently separate and remove the substances to be removed such as small-particle virus contained in a solution and, at the same time, useful recovering substances such as protein can be efficiently permeated and the decrease of its transmission rate with elapse of time is small. The porous hollow fiber membrane of the present invention is characterized in that the filtration downstream surface thereof has dot-shaped or slit-shaped pores, the filtration upstream surface thereof is a network structure or a fine particle aggregate structure, the central region of the membrane is composed of a substantially homogeneous structure, the membrane wall is composed of a structure having substantially no macrovoids, the permeability for pure water is 10 to 300 L/(h·m2·bar) and the permeability for a 0.1% by weight solution of bovine ?-globulin is 30 to 100% of the permeability for pure water.
    Type: Grant
    Filed: December 24, 2009
    Date of Patent: October 24, 2017
    Assignee: TOYO BOSEKI KABUSHIKI KAISHA
    Inventors: Hideyuki Yokota, Noriaki Kato, Hirofumi Ogawa, Junsuke Morita
  • Patent number: 9731250
    Abstract: Disclosed is a method for producing a hollow fiber carbon membrane using a hollow fiber carbon membrane-forming material by means of a dry method or dry-wet method comprising a spinning step, a drying step, an infusibilization step, and a carbonization step as basic steps; wherein in the infusibilization step, heat treatment is performed at least two times at different temperatures, with the second temperature being higher than the first temperature. It is preferable that the second heat treatment is performed directly after the first treatment is performed, without once cooling to room temperature. The obtained hollow fiber carbon membrane has improved permeability, without reducing its separation coefficient.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: August 15, 2017
    Assignee: NOK Corporation
    Inventors: Hirokazu Yamamoto, Yusuke Ikawa, Yutaka Koda
  • Patent number: 9725344
    Abstract: A spiral wound filtration assembly including: i) a pressure vessel comprising a feed port, concentrate port and permeate port; ii) at least one spiral wound membrane module comprising at least one membrane envelop wound around a permeate tube which forms a permeate pathway to the permeate port; and iii) a bioreactor having a cylindrical outer periphery extending along an axis (Y) from a first end to a second end, an inlet located near the first end, and an outlet located near the second end; wherein the spiral wound membrane module and bioreactor are serially arranged within the pressure vessel.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: August 8, 2017
    Assignee: Dow Global Technologies LLC
    Inventors: Steven D. Jons, Jon E. Johnson
  • Patent number: 9718031
    Abstract: Disclosed herein is a composite hollow fiber polymer membrane including a porous core layer and a selective sheath layer. The porous core layer includes a polyamide-imide polymer, or a polyetherimide polymer, and the selective sheath layer includes a polyimide polymer, which is prepared from monomers A, B, and C. The monomer A is a dianhydride of the formula wherein X1 and X2 are independently halogenated alkyl group, phenyl or halogen and R1, R2, R3, R4, R5, and R6 are independently H, alkyl, or halogen. The monomer B is a diamino cyclic compound without a carboxylic acid functionality and the monomer C is a diamino cyclic compound with a carboxylic acid functionality. The polyimide polymer further includes covalent ester crosslinks. Also disclosed herein is a method of making the composite polymer membrane and a process for purifying natural gas utilizing the composite polymer membrane.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: August 1, 2017
    Assignees: Chevron U.S.A. Inc., Georgia Tech Research Corporation
    Inventors: Canghai Ma, William John Koros