Abstract: A method for selectively removing leukocytes from a suspension which also contains platelets, such as a platelet concentrate or whole blood. The method includes passing the suspension through a filter which includes a polysaccharide-type coating. The coating may include one or more of hydroxypropylmethyl cellulose, hydroxybutylmethyl cellulose, dextran and hydroxyethyl starch. Also provided is a filter for selectively removing leukocytes from a suspension which also contains platelets. The filter includes a substrate which is coated with a polysaccharide-type composition.

Abstract: A ceramic composite comprising ceramic fibers and glass microparticles bound together as a porous matrix with a ceramic binder provides baffles for cryogenic fluids in a storage container.

Abstract: The invention provides a leukodepletion filter including a plurality of glass fiber filter pads, and a plurality of non-woven polyester fiber filter pads, sealed within a filter housing.

Abstract: The present invention provides a method and apparatus for separating a blood sample having a volume of up to about 20 milliliters into cellular and acellular fractions. The apparatus includes a housing divided by a fibrous filter into a blood sample collection chamber having a volume of at least about 1 milliliter and a serum sample collection chamber. The fibrous filter has a pore size of less than about 3 microns, and is coated with a mixture including between about 1-40 wt/vol % mannitol and between about 0.1-15 wt/vol % of plasma fraction protein (or an animal or vegetable equivalent thereof). The coating causes the cellular fraction to be trapped by the small pores, leaving the cellular fraction intact on the fibrous filter while the acellular fraction passes through the filter for collection in unaltered form from the serum sample collection chamber.

Abstract: The invention aims to provide an apparatus for purifying water containing organic halides therein improved so as to substantially achieve perfect removal of organic halides from water which has conventionally been considered to be impossible. The object set forth above is achieved, according to the invention, by an apparatus for purifying water containing organic halides therein characterized in that particles, fibers, nonwoven fabric, porous body or sintered body containing hydroxycarboxylic acid or polymer thereof having a chemical structure expressed by general formula: ##STR1## where R1-R6 are identical or different and represent hydrogen atom, hydroxyl-, carboxyl-, amino-, cyano- or alkyl-group having 1-5 carbons, p represents a natural number 1-10, and q and r represent an integer 0-10) as a main ingredient is used as organic halide adsorbent; and a residual concentration of organic halides in water can be decreased to the order of ppb.

Abstract: The invention provides a sheet filter medium having autogenously bonded uncrimped conjugate fibers which contain a polyolefin and another thermoplastic polymer that have different melting points. The filter medium has a density between about 0.07 g/cm.sup.3 and about 0.2 g/cm.sup.3. The invention additionally provides a three-dimensionally thermoformed filter medium that has a density between about 0.07 g/cm.sup.3 and about 0.5 g/cm.sup.3.

Abstract: A chemically charged-modified filter for removing charged, micron to sub-micron sized particles from an aqueous liquid, the filter being composed of a filter sheet having a plurality of individual exposed surfaces, at least a portion of which having a surface energy of less than about 45 dynes per centimeter; amphiphilic macromolecules adsorbed onto at least some individual exposed surfaces having a surface energy of less than about 45 dynes per centimeter; and chemical charge modifiers incorporated onto at least a portion of the amphiphilic macromolecules; so that when said charge-modified substrate is in contact with the aqueous liquid containing the charged, micron to sub-micron sized particles, said particles are adsorbed onto the chemically charge-modified filter.

Abstract: A tobacco filter material containing fibers which have a core and a surface layer which surrounds the core, wherein the core comprises a non-esterified cellulose and the surface layer comprises a cellulose ester. The fiber may be (A) a cellulose fiber coated with a cellulose ester or (B) a fibrous cellulose derivative with its surface layer esterified by an organic acid and having an average degree of substitution of not more than 1.5. Wood pulp can be used as the cellulose fiber and the amount of the cellulose ester in the coated cellulose (A) is 0.1% by weight or more. The cellulose derivative (B) has its surface layer esterified with an organic acid and retains a non-esterified core portion. This cellulose derivative may be obtained, for example, by the non-catalytic liquid phase treatment of a cellulose fiber with an organic acid and an organic acid anhydride or halide.

Abstract: Melt-blown fibrous webs having a uniform structure for use in processing biological fluids are disclosed.

Abstract: A homogeneous mixture of a base and a binder material or fiber that is compressed to form a mat or sheet of selected porosity. The binder material has at least a surface with a melting temperature lower than that of the base fiber. The sheet is formed into a selected geometric shape and thermally fused to bind the base fiber into a porous filter element. The preferred shape is a helically wound tube of plural sheets, each sheet being self-overlapped and compressed to overlap another sheet. Each sheet preferably heated and compressed individually and the sheets may be selected to have different porosities and densities. The binder fiber is selected from the group consisting of thermoplastic and resin, and the base fiber is selected from the group consisting of thermoplastic and natural.

Abstract: A method for removing leukocytes from a leukocyte-containing suspension comprising passing said suspension through a filter including a nitrocellulose membrane having a pore size of 5-15 .mu.m.

Abstract: The present invention relates to a filter including a filter element having a sucession of inner connected pleats. The pleats have successive pleat tips which define an outer boundary of the filter element. Covering the entire outer boundary of the filter element is a permeable generally inelastic sheet which extends across successive pleat tips. The sheet is adhesively affixed to the pleat tips for maintaining spacing of the pleats. The sheet comprises of plurality of randomly arranged plastic filaments which are bonded to each other junctions between the filaments and define a plurality of randomly spaced and shaped opening for allowing substantially unrestricted flow of a fluid through the sheet.

Abstract: Novel blood cell fractionation means utilizes conventional filters coated with high molecular weight polyethylene oxide derivatives crosslinked to prevent leaching from filter surfaces. These fractionation means have a special efficacy in binding white blood cells from whole blood while simultaneously allowing red cells and platelets to pass in the effluent phase.

Abstract: A plate fiber with high odor and toxin removing and water absorbing capacity and its manufacturing processes includes a catalyzer I such as hydrochloric acid, a catalyzer II such as formalin, a vegetable starch, PVA, and active carbon. The materials are orderly processed through mixing, stirring and being coated on a plate fiber. Then the plate fiber passes through a foaming step, an acid removing step, a cooling step, a washing and compressing step, a drying step, becoming a plate filter washable and able to remove odor and toxin sufficiently and absorb water.

Abstract: A filtering medium in the form of a sheet of paper for filters for fluids in general, wherein the paper impregnating agent is an aqueous emulsion of:an anionic aqueous disperse system of a copolymer based on n-butylacrylate-styrene.Dosage: 20%-50% by weight;an aqueous disperse system of a copolymer which can be thermally cross-linked and is based on butyl acrylate and acrylonitrile.Dosage: 30%-70% by weight;an aqueous disperse system of melamine-formaldehyde resin, etherified with methanol.Dosage: 1%-20% by weight;an aqueous disperse system of fluorocarbon resin.Dosage: 5%-40% by weight;an aqueous emulsion of organopolysiloxane.Dosage: 0%-15% by weight.

Abstract: The present invention relates to a method and to a device for separating plasma from whole blood. The method and device utilize a permeable non-glass fiber matrix containing a polyol which is capable of clumping red blood cells. The matrix, in the absence of such a polyol, would otherwise be porous to red blood cells. The polyol-containing matrix has a first surface and a second surface such that a whole blood sample which is applied to the first surface flows directionally toward the second surface. Plasma separated from whole blood becomes available at the second surface of the matrix and can be tested for the presence of a particular analyte, such as glucose or fructosamine, as provided by multi-layer test devices of the present invention.

Abstract: Leucocyte depletion filter assemblies decrease the leucocyte content of a leucocyte-containing liquid at a flow rate of greater than about 25 milliliters per minute. These filter assemblies are suitable for use in an extracorporeal circuit. Methods for removing leucocytes and other deleterious matter are also disclosed.

Abstract: A filter element (10) comprises a porous, thick-walled, integral, self-supporting, resin impregnated and bonded fibrous, tubular filter structure (11) having a hollow core (15); an inner shell (20) of a first large pore size porous media adjacent the hollow core and forming the majority of the filter structure; and an outer shell (21) of a second small pore size porous media, finer than the first porous media and adjacent the inner shell, the first and second porous media being resin impregnated and bonded.

Abstract: An adsorbent filter for removing caffeine from liquids. The filter is composed of a liquid permeable matrix of fibrous material having individual exposed surfaces; and a distribution of adsorbent clay minerals attached to individual exposed surfaces of the fibrous material by substantially non-transient bonding, so that passage of a liquid having a caffeine concentration ranging from about 20 to about 100 mg per 100 mL of liquid through the matrix for a contact time of less than about 2 minutes results in at least a 40 percent reduction in the caffeine concentration of the liquid. The matrix of fibrous material may be selected from woven fabrics, knit fabrics and nonwoven fabrics. The adsorbent clay minerals include, for example, sodium bentonite clays, calcium bentonite clays, acidified bentonite clays, and modified bentonite clays containing a flocculating agent.

Abstract: A leukodepletion filter is provided including glass fiber filter pads and non-woven polyester fiber filter pads sealed within a filter housing. The filter is designed such that a fluid, such as whole blood, packed red blood cells, platelets or plasma, is conducted through the glass fiber filter pads before the non-woven polyester fiber filter pads. A method is further provided for leukodepleting a body fluid by filtering the body fluid through glass fiber filter pads and also filtering the body fluid through non-woven polyester fiber filter pads. After filtering, the body fluid is collected.

Abstract: The present invention relates to a method and to a device for separating plasma from whole blood. The method and device utilize a permeable non-glass fiber matrix containing a polyol which is capable of clumping red blood cells. The matrix, in the absence of such a polyol, would otherwise be porous to red blood cells. The polyol-containing matrix has a first surface and a second surface such that a whole blood sample which is applied to the first surface flows directionally toward the second surface. Plasma separated from whole blood becomes available at the second surface of the matrix and can be tested for the presence of a particular analyte, such as glucose or fructosamine, as provided by multi-layer test devices of the present invention.

Abstract: Disposable paper filters suitable for removal of contaminants from fluids such as water or air are disclosed. Specific embodiments include single-ply and multi-ply filters in which metal removal additives and/or halogen and organic contaminant removal additives have been distributed during the manufacturing process. Special manufacturing methods for producing such composite filters are also described.

Abstract: A high efficiency and high capacity filter medium including a top layer of fibrous felt material, an intermediate layer of melt-blown material, and a substrate layer needled together into an integrated layer of filter material. The substrate layer is formed of a layer of composite fiber including a group of melt-blown fibers interspersed between groups of spun-bonded fibers. Alternatively, the substrate layer is formed of spun-bonded material.

Abstract: A cylindrical filter is disclosed which comprises a wound up layer of a fibrous aggregate comprising melt-adhesive composite fibers bonded each other through the melt of a melt-adhesive component in the composite fibers and a layer of non-woven fabric of glass fibers, the layer of non-woven fabric is arranged on the outer surface of the wound up layer of the fibrous aggregate, and glass fibers have a smaller diameter than that of the melt-adhesive composite fibers. The cylindrical filter has an excellent filter rating and filter life.

Abstract: The present invention provides a polymeric, particularly aramid, fibrous nonwoven web having a relatively small pore size. The present inventive fibrous nonwoven web preferably has a high titer reduction with respect to bacteria such as Pseudomonas diminuta and viruses as exemplified by PR772 coliphage. The present invention further provides a method of filtering a fluid by passing a fluid through the present inventive fibrous nonwoven web, as well as a filter element incorporating the present inventive fibrous nonwoven web.

Abstract: A method for removing leukocytes from a leukocyte-containing suspension comprising passing said suspension through a filter including a nitrocellulose membrane having a pore size of 5-15 .mu.m.

Abstract: An efficient method removes oxidants from fluids (gases and liquids, particularly air) by means of solid phase extraction or reaction. The solid phase extraction or reaction medium comprises a porous, preferably fibrous, polymeric, membrane or web in which are incorporated oxidant scavenger particulates. Typical oxidants removed in the method include ozone, oxides of nitrogen, halogen, and peroxides. The method of the invention protects organic analytes in analytical applications and removes oxidants in remediation applications by use of oxidant scavenger particles in porous membranes.

Abstract: A sheet article for solid phase extraction or solid phase reaction has at least one sorptive polymer pulp at least one of sorptive and reactive particulate. The article can be used in a method of separating an analyte from a fluid by passing a fluid containing an analyte through a sheet article containing poly(p- or m-phenylenephthalamide) pulp and solid phase particles.

Abstract: Filtration medium is formed of a mass of nonwoven melt blown support and filtration fibers which are integrally co-located with one another. The support fibers have, on average, relatively larger diameters as compared to the filtration fibers which are integrally co-located therewith. Preferably, the filtration medium is disposed within at least one annular zone of a filtration element, for example, a disposable cylindrical filter cartridge having an axially elongate central hollow passageway which is surrounded by the filtration media. A depth filter cartridge in accordance with the present invention may thus be formed having one or more additional filtration zones (which additional filtration zones may or may not respectively be provided with integrally co-located support fibers) in annular relationship to one another.

Abstract: A gas plasma treated porous medium and method of using such a medium to separate or remove materials such as components of biological fluids.

Abstract: The present invention provides an apparatus for separating a relatively large volume of blood into cellular and acellular fractions without the need for centrifugation. The apparatus comprises a housing divided by a fibrous filter into a blood sample collection chamber having a volume of at least about 1 milliliter and a serum sample collection chamber. The fibrous filter has a pore size of less than about 3 microns, and is coated with a mixture of mannitol and plasma fraction protein (or an animal or vegetable equivalent thereof). The coating causes the cellular fraction to be trapped by the small pores, leaving the cellular fraction intact on the fibrous filter while the acellular fraction passes through the filter for collection in unaltered form from the serum sample collection chamber.

Abstract: The present invention provides a supported fibrous web assembly comprising a support material adhered to a nonwoven web of multicomponent fibers comprising a first polymer and a second polymer such that the second polymer is present on at least a portion of the surface of the multicomponent fibers and has a softening temperature below the softening temperatures of the first polymer and the support material, wherein the supported fibrous web assembly has a water flow rate of at least about 20% of the water flow rate of the nonwoven web of multicomponent fibers alone. The present inventive supported fibrous web assembly can further comprise a second fibrous web, which is adhered to the nonwoven web of multicomponent fibers such that the nonwoven web of multicomponent fibers is positioned between the second fibrous web and the support material, and wherein the supported fibrous web assembly has a water flow rate of at least about 20% of the water flow rate of the second fibrous web alone.

Abstract: Novel blood cell fractionation means utilizes conventional filters coated with high molecular weight polyethylene oxide derivatives crosslinked to prevent leaching from filter surfaces. These fractionation means have a special efficacy in binding white blood cells from whole blood while simultaneously allowing red cells and platelets to pass in the effluent phase.

Abstract: Filter devices for simultaneously removing leukocytes and methylene blue from whole blood or blood fractions are disclosed. One type of device comprises (1) a housing surrounding (2) activated carbon and (3) a mechanically stable polymeric material which may optionally be modified to attach a ligand for leukocytes. General methods for removing leukocytes and methylene blue from blood and plasma are also disclosed.

Abstract: A system for collecting and processing donated blood comprises a first porous medium interposed between a blood collection bag and a satellite bag and a second porous medium interposed between the blood collection bag and another satellite bag. The porous media are leucocyte depletion media. The system may also include one or more of the following: a red cell barrier medium, a separation medium, a gas inlet, and a gas outlet. The system can be used to centrifuge whole blood into one or more components, and includes a means for protecting the system during centrifugation.

Abstract: The present invention provides a method of preparing a support for a filtration medium comprising passing a sheet of nonwoven fibrous polymeric material having first and second sides through a calender which comprises a nondeformable roll and a resilient roll, the nondeformable roll being maintained at a temperature below the melting temperature of the material, so as to increase the smoothness of the first side of the material which contacted the resilient roll. A filtration medium support material prepared in accordance with the method of the present invention, as well as a filter comprising a filtration medium and that filtration medium support material, are also provided by the present invention.

Abstract: There is provided a fiber bed for removing liquid aerosols and soluble solids from a gas stream in a fiber bed mist eliminator. The fiber bed is in the form of a flexible mat having a void fraction of greater than about 0.89 and greater than about 700 net collection targets. The mat includes a layer of collecting fibers having an average fiber diameter between about 1 and about 5 .mu.m. The collecting fibers are stabilized by a plurality of stabilizing fibers which penetrate into and are disposed interstitially within the collecting fiber layer. The improved fiber bed of the present invention is field-replaceable and, by utilizing fibers having a small average diameter, the thickness of the fiber bed may be reduced.

Abstract: The invention concerns a filter material particularly useful in the manufacture of tea bags, coffee bags, coffee filters and the like. The filter material includes an at least two layer non-woven substrate material wherein the two layers are essentially planar and superimposed, one layer is composed of natural fibers and one layer is composed of synthetic fibers. The synthetic fiber layer includes a plurality of individual plastic fibers which are deposited in a heated state on the natural fiber layer. The plastic fibers fuse with each other and also fuse with the natural fibers of the other layer. The filter material provides the particular advantage, due to the deposition of the individual plastic fibers on the natural fibers, of covering or closing a large number of pores or ducts in the natural fiber layer.

Abstract: A composite membrane is provided which includes a base material and an ion exchange resin. The base material has a microstructure characterized by nodes interconnected by fibrils, or a microstructure characterized by fibrils with no nodes present. The ion exchange resin substantially impregnates the membrane such that the membrane is essentially air impermeable.

Abstract: Disclosure describes ball-like structures formed from bundled, crimped fibers rounded around a central portion thereof as a core, the core being formed with a molten-fused structure and having the following stipulations:(a) a density of the molten-fused structure is not less than 75% based on a density of the crimped fibers forming the ball-like structures.(b) a length of the molten-fused structure is 5 to 50% based on a diameter of the ball-like structures, and(c) a withdrawing strength of a crimped fiber strand connected with the molten-fused structure is not less than 50% based on a linear strength of the crimped fiber strand itself used for the ball-like structures.

Abstract: Composite articles are useful for separating mercury from fluids. The composite articles can be porous supports comprising an inert substrate having immobilized thereon finely divided gold optionally in combination with a tin salt coating. The porous support can be a particulate or porous fibrous webs. Alternatively, the composite articles can comprise a porous fibrous membrane having enmeshed therein the aforementioned porous supports which can be in particulate or fibrous forms. The method for separating elemental, ionic, or organic mercury in fluids comprises the step of contacting and passing a fluid containing mercury through a support comprising a porous, high surface area, inert substrate on which is immobilized finely divided elemental gold at a controlled rate for a time sufficient for the mercury to sorb to the elemental gold and to provide an immobilized gold-mercury amalgam on the support. If a tin salt also is immobilized on the inert substrate, mercury-tin salt can also be formed.

Abstract: Disposable paper filters suitable for removal of contaminants from fluids such as water or air are disclosed. Specific embodiments include single-ply and multi-ply filters in which metal removal additives and/or halogen and organic contaminant removal additives have been distributed during the manufacturing process. Special manufacturing methods for producing such composite filters are also described.

Abstract: Apparatus for washing-down serigraphical frames by means of a cleaning liquid comprises a sing-like unit having V or U-shaped ends, in which unit the serigraphical frames are placed, a scavenging hose with affixed brush, a filter section, a circulation pump, a sludge discharge system and a recirculation system for liquid. The filter section comprises a filter tray having V or U shaped cross-sections and a loosely fitted recovable filter mat of a chemically resistant material, preferably a polyester coating glass fibre material or polypropylene, with optimum surface. The collected sludge is discharged at intervals through the bottom of the tank unit, the unit cleaning liquid is recirculated continuously after filtration and added with fresh cleaning liquid. The apparatus is equipped with a double-acting suction system for vapours from the cleaning liquid and involves substantial advantages to the working environment.

Abstract: A device for processing donated blood comprises a porous medium interposed between the collection bag and a satellite bag into which a component separated by centrifugation can be expressed, the filter element preferably having a CWST of about 70 to about 115 dynes/cm. The porous medium blocks red blood cells, but allows platelets to pass therethrough.

Abstract: A wool filter for a dust-proof mask is disclosed, in which wool fibers are mixed with chemical resin film slitting yarns so as to manufacture a non-woven fabric, thereby doubling the electrostatic force to improve the dust filtering function. In manufacturing the wool filter for a dust-proof mask, 40 to 90 weight % of wool yarns is uniformly mixed with 10 to 60 weight % of chemical resin film slitting yarns, preferably polyolefinic resin film slitting yarns.

Abstract: A method of preparing paper for filter bags, the method of the type comprising a step during which a non-woven paper is prepared comprising two superposed layers, namely a layer based on synthetic fibers and a layer of cellulose fibers, by a technique which is known per se, wherein the method includes a subsequent step of subjecting the non-woven paper to a calendering operation between a support structure and a heated cylinder having projections. The present invention also provides apparatus for implementing the method and products obtained in this manner.

Abstract: The invention is a demineralization apparatus comprising an anode chamber disposed at one end of a vessel having an anode at the inside of the anode chamber. A cathode chamber is disposed at the other end of the vessel, having a cathode at the inside of the cathode chamber. At lease one diluting chamber and at least one concentrating chamber are located alternately between the anode chamber and the cathode chamber. The diluting chamber has an anion exchange membrane on the anode chamber side and a cation exchange membrane on the cathode chamber side. The diluting chamber has an inlet for water to be treated and an outlet for demineralized water. The concentrating chamber has an inlet for water and an outlet for ion-concentrated water. The diluting chamber contains a cloth comprising a mixture of strongly acidic cation exchange fibers, strongly basic anion exchange fibers and ionically inactive synthetic fibers. Preferably, the mixture contains from 20 to 70% by weight ionically inactive synthetic fibers.

Abstract: A filtering medium which is unchanged in the maximum pore size even when heating sterilization, high temperature filtration, etc. are carried out, yet has a high tensile strength, can be processed into pleat-form and also is applied to high precision filtration, is provided, which filtering medium is a product having a non-woven fabric composed of 20 to 80% by weight of lower melting point microfine fibers and 80 to 20% by weight of higher melting point microfine fibers having a melting point higher by 10.degree. C. or higher than that of the lower melting point microfine fibers, the respective fibers being hot-melt-adhered to one another through the lower melting point microfine fibers, hot-melt-adhered to a hot-melt-adhesive net, and having a maximum pore size of 120 .mu.m.

Abstract: In a mechanical cell for blending elastomer particles and solution into uniform mixtures, a solid core with an entrance surface, an exit surface spaced apart from and substantially parallel to the entrance surface, and a plurality of minute core passageways therebetween for flow of an elastomer-containing hydrocarbon solution from the entrance surface to the exit surface, the passageways have a characteristic dimension of predetermined size to reduce globules of elastomer to small particles distributed evenly in liquid hydrocarbon solution without plugging the passageways. Typically the passageways have a characteristic dimension of predetermined size to reduce globules of elastomer selected from the group consisting of natural rubber, styrene-butadiene rubber, polybutadiene rubber, polyisoprene, a nitrile rubber, and a copolymer of a 1,4-conjugated diene and a vinyl aromatic monomer, to small particles distributed evenly in liquid hydrocarbon solution comprising a vinyl aromatic monomer.

Abstract: A high efficiency leucocyte-depletion filter for use with packed red cell concentrate derived from freshly drawn blood comprises a fibrous filter medium with a pore size of from about 0.5 to less than 3.6 .mu.m and a CWST of from 53 to about 80. The filter is preferably used in conjunction with a gel prefilter and, optionally, a microaggregate filter so as to minimize clogging. In a preferred embodiment, the voids volume is about 60% to about 85%.