Including Regulating Pressure To Control Constituent Gradient At Membrane Or To Prevent Rupture Of Membrane Patents (Class 210/637)
  • Patent number: 10767457
    Abstract: A frac system that includes a hydraulic energy transfer system configured to exchange pressures between a first fluid and a second fluid.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: September 8, 2020
    Assignee: ENERGY RECOVERY, INC.
    Inventors: Farshad Ghasripoor, Jeremy Grant Martin, Prem Krish, Baji Gobburi
  • Patent number: 10717048
    Abstract: An environmental water system may include an ultrafiltration membrane, a reserves osmosis (RO) system, a waste water tank, a mixer, a total dissolved solids (TDS) controller valve, a connector, and a water tap. The environmental water system can provide pure water which is filtered through the ultrafiltration membrane and RO system. Also, a user can operate the TDS controller valve depending on the actual use requirement so as to have different TDS values of water from the water tap.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: July 21, 2020
    Inventor: Hsiang-Shih Wang
  • Patent number: 10687526
    Abstract: Devices for the preparation of depleted blood products that provide for the depletion of oxygen, carbon dioxide, or oxygen and carbon dioxide are described. In addition, devices for the replenishment of oxygen and other gases to an anaerobic blood product are described. Methods and systems incorporating depletion and addition devices are provided to optimize the preparation, storage and transfusion of blood products to a recipient are described.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: June 23, 2020
    Assignee: Hemanext Inc.
    Inventors: Steven F. Levesque, Thomas R. Ruth
  • Patent number: 10640408
    Abstract: A system for recovery of animal byproducts and providing water reuse from an animal processing plant waste stream. In one embodiment of the invention there is an equalization tank forming part of an animal processing plant that is mechanically filtered to recover animal byproducts from a water mixture in the equalization tank. In another aspect of the invention there is a skimmer tank that contains a skimmer mixture with water and animal byproducts. The system mechanically separates the animal byproducts from the skimmer mixture in a manner that is suitable for human consumption. The system also allows the separated water to be reused in the animal processing plant.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: May 5, 2020
    Assignee: AIR & LIQUID SYSTEMS INC.
    Inventors: James E. Miller, Gordon T. Urquhart
  • Patent number: 10598162
    Abstract: A pump in desalination systems has four cylinders, each having a double acting piston. Each cylinder and piston defines a feed chamber and a recovery chamber. The pistons connect to a common drive. The connection to the common drive is such that the pistons reciprocate in a sequence equally spaced in time. Reciprocating valving for each piston is driven by the common drive to be 90 degrees out of phase with the respective piston. The valving connects the recovery chamber alternately to an inlet manifold for an intake stroke of the piston relative to the recovery chamber, and to an outlet manifold for a discharge stroke of the piston relative to the recovery chamber. A brief period of closure coincides with top dead centre and bottom dead centre of the piston, during which the recovery chamber is blocked off from both the inlet and outlet manifolds. The reciprocating valving is midway between its top dead centre and bottom dead centre during the period of closure.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: March 24, 2020
    Assignee: KATADYN DESALINATION, LLC
    Inventor: Christopher John Dent
  • Patent number: 10449472
    Abstract: Disclosed is a centrifugal filtration apparatus including a casing, a shaft, a stand tube, a rotor, and a stereoscopic filter. The shaft is vertically installed in the casing and guides a fluid to an upper end of the casing. The stand tube rotates about the shaft and sprays the fluid to the upper end of the casing. The rotor rotates along with the stand tube and forms a space in the casing to receive and filter the fluid sprayed from the stand tube. The stereoscopic filter includes a plate member and wire members. The plate member is rolled up around the stand tube and is installed in the rotor. The wire member is installed between layers of the plate member to secure a gap between the layers of the plate member and forms a filter layer to filter the fluid that flows between the layers of the plate member.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: October 22, 2019
    Assignee: Shin Heung Precision Co., Ltd.
    Inventors: Yong Keun Kim, Tae Ja Kim, Seok Jae Yang
  • Patent number: 10329171
    Abstract: A method for treating water including intaking a first amount of water from a first source into a plurality of treatment blocks, treating the first amount of water, outputting aqueous treated water streams from each of the plurality of treatment blocks, separating the aqueous treated water streams from each of the plurality of treatment blocks into aqueous permeate streams and concentrate reject streams, monitoring each of the aqueous permeate streams, controlling the operation of at least one of the plurality of treatment blocks based on predefined water-characteristic tolerances that fall within a predetermined concentration range based on the different qualities of the aqueous permeate streams, outputting a product water stream into an injection water reservoir or blend point, the product water stream including the aqueous permeate stream, intaking a second amount of water from a second source, treating the second amount of water, and discharging the dischargeable water stream.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: June 25, 2019
    Assignee: Water Standard Company (MI)
    Inventor: Lisa Henthorne
  • Patent number: 10324070
    Abstract: A system, module and method for continuous or batch single-pass countercurrent tangential chromatography are disclosed for bind/elute and negative chromatography applications. The system includes binding, washing, elution (for bind/elute), regeneration, and equilibration single-pass modules. The resin slurry flows in a continuous single pass at steady-state through each module, while corresponding buffers flow countercurrent to the slurry facilitating efficient product and impurity extraction. The module and system include retentate pumps for better process robustness and control. A resin tank configured to be reversibly isolated from the single-pass modules facilitates a closed and disposable system.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: June 18, 2019
    Assignee: CHROMATAN INC.
    Inventor: Oleg Shinkazh
  • Patent number: 10307526
    Abstract: A method and a device are disclosed for regulating an ultrafiltration in a dialysis treatment, in which the blood to be ultrafiltered in an extracorporeal blood circulation (109) flows through a blood chamber (110) of a dialyzer (113), which is subdivided by a semipermeable membrane (111) into a blood chamber (110) and a dialysis fluid chamber (108), and dialysis fluid in a dialysis fluid circulation (109) flows through the dialysis fluid chamber (108) of the dialyzer (113).
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: June 4, 2019
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Alexander Heide, Dejan Nikolic, Arne Peters, Christoph Wiktor
  • Patent number: 10280097
    Abstract: Separation processes using osmotically driven membrane systems are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane. Enhanced efficiency may result from using low grade waste heat from industrial or commercial sources. Pre-treatment and post-treatment may also enhance the osmotically driven membrane processes.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: May 7, 2019
    Assignee: Oasys Water LLC
    Inventor: Robert L. McGinnis
  • Patent number: 10166510
    Abstract: A feed of at least one of (a) a source liquid including a solvent with a dissolved impurity and (b) a retentate of the source liquid is pumped in a substantially closed loop through a liquid-separation module. The liquid-separation module includes a membrane that passes at least partially purified solvent to a permeate side of the membrane while diverting the impurity in a retentate on the retentate side of the membrane. The purified solvent is extracted from the permeate side of the membrane; and the retentate from the liquid-separation module is pumped to or through a pressurized reservoir with a variable volume for the feed component and recirculated as a component of the feed. Over time, the volume for the feed is reduced and the pressure applied to the feed in the reservoir is increased to balance against an increasing difference in osmotic pressure across the membrane.
    Type: Grant
    Filed: November 13, 2016
    Date of Patent: January 1, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: David Elan Martin Warsinger, John H. Lienhard, V, Emily Winona Tow, Ronan Killian McGovern, Gregory Parker Thiel
  • Patent number: 10151679
    Abstract: A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 ?m in diameter, and even as small as 2 ?m in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at least one or more of the particles in the stream will penetrate a defective region or regions within the membrane but will not penetrate in the integral region of the membrane. Wetting of the filter is not required.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: December 11, 2018
    Assignee: EMD Millipore Corporation
    Inventors: Salvatore Giglia, David Nhiem, Gabriel Tkacik
  • Patent number: 10119897
    Abstract: A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 ?m in diameter, and even as small as 2 ?m in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at least one or more of the particles in the stream will penetrate a defective region or regions within the membrane but will not penetrate in the integral region of the membrane. Wetting of the filter is not required.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: November 6, 2018
    Assignee: EMD Millipore Corporation
    Inventors: Salvatore Giglia, David Nhiem, Gabriel Tkacik
  • Patent number: 10099991
    Abstract: This invention relates to a process for the separation of dicarboxylic acids from aqueous mixtures of CV8C24 mono- and dicarboxylic acids. In particular this invention relates to a process for the separation and purification of the said mixtures which uses an ultrafiltration stage.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: October 16, 2018
    Assignee: Novamont S.p.A.
    Inventor: Antonio Verdoliva
  • Patent number: 10046278
    Abstract: Methods for controlling a spinning membrane separator so as to limit fouling of the membrane by changing the rotation rate of the spinning membrane in response to the fouling rate, while maintaining a constant outlet cellular concentration. Increasing the spinner rotation rate will increase the strength of the Taylor vortices generated within the separator by the spinning of the membrane, which should reduce fouling of the membrane. The goal of the method is to rotate the spinning membrane at the slowest rate possible without unacceptable fouling. Two specific methods to control fouling are disclosed. In a first, unidirectional method, the spin rate of the membrane is only increased in response to undesirable fouling in order to prevent the fouling from continuing. In a second, bidirectional method, the spin rate of the membrane may be either increased or decreased in response to the measured fouling rate in order to maintain the fouling rate within a desired range.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: August 14, 2018
    Assignee: Fenwal, Inc.
    Inventors: Benjamin E. Kusters, Kyungyoon Min
  • Patent number: 10046100
    Abstract: An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.
    Type: Grant
    Filed: January 7, 2017
    Date of Patent: August 14, 2018
    Assignee: NXSTAGE MEDICAL, INC.
    Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
  • Patent number: 10029211
    Abstract: A process for the regeneration of a membrane wall in a distillation apparatus, wherein a distillation apparatus having one or more evaporation and condensation stages is provided, each evaporation and condensation stage having at least one flow channel conducting a liquid, said flow channel being at least partially confined by a vapor-permeable and liquid-impermeable membrane wall, wherein vapor emerging from the liquid passes through the membrane wall. The liquid is removed from the at least one flow channel, wherein, after the removal of the liquid, the membrane wall is surrounded on both sides by a gas atmosphere, but is still wetted with liquid, and this liquid is removed by adjusting the gas atmosphere surrounding the membrane wall such that the partial pressure of the liquid in the gas atmosphere is lower than the vapor pressure of the liquid wetting the membrane wall.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: July 24, 2018
    Assignee: Major Bravo Limited
    Inventors: Markus Wenzel, Sebastian Büttner, Dominik Weisz, Wolfgang Heinzl
  • Patent number: 9974894
    Abstract: A blood pump system and methods for the use and operation of such a blood system is described, wherein the blood pump system includes an implantable pump and an implantable flow measurement device. A processing device receives indications of a number of pump parameters such as pump voltage, pump current and pump speed. Flow rate is determined based on the pump parameters, and this determined flow rate is compared to the actual flow rate as measured by the flow measurement device. In certain embodiments, the flow measurement device may be periodically energized to make the comparison, then powered off to reduce power consumption. The time period in which the flow measurement device is powered off is based on the difference between the determined and the actual flow rates.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: May 22, 2018
    Assignee: ReliantHeart, Inc.
    Inventor: Gino F. Morello
  • Patent number: 9956527
    Abstract: A guide member for directing gas bubble flow along a membrane surface, the guide member having first and second side edges defining a channel for gas bubbles to flow along, the channel having an open bottom end through which the gas bubbles can enter the channel and an open top end through which the bubbles can exit the channel, and a diverting means adjacent the channel bottom end arranged to direct at least some of the incident gas bubbles in a first direction towards the channel bottom end. A membrane module assembly and a membrane filter system including the guide member.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: May 1, 2018
    Assignee: Bionest Technologies Inc.
    Inventor: Garfield R. Lord
  • Patent number: 9938970
    Abstract: The present invention provides apparatus, including a hydronic sensorless pumping system, that features a signal processor or processing module configured to receive signaling containing information about motor readout values of power and speed, and also about pump and system characteristics equations together with empirical power equations that are constructed by a polynomial best-fit function together with pump affinity laws based upon a pump curve published by a pump manufacturer; and determine corresponding signaling containing information about a pump or system pressure and a flow rate at the motor readout values of power and speed, based upon the signaling received.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: April 10, 2018
    Assignee: Fluid Handling LLC
    Inventors: Andrew A. Cheng, James J. Gu, Graham A. Scott
  • Patent number: 9933407
    Abstract: An apparatus and process of using existing process water sources such as cooling towers, fountains, and waterfalls is provided in which the water sources are utilized as monitoring system for the detection of environmental agents which may be present in the environment. The process water is associated with structures and have an inherent filtering or absorbing capability available in the materials and therefore can be used as a rapid screening tool for quality and quantitative assessment of environmental agents.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: April 3, 2018
    Assignee: SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC
    Inventors: Robin Brigmon, Mark T. Kingsley
  • Patent number: 9739750
    Abstract: An oil removal device for removing oil from a stream (103) of oil-separated sample droplets (104) is disclosed. The oil removal device comprises a sample delivery channel (101) for conducting the stream of sample droplets to an outlet (102). A porous, hydrophobic and oleophilic absorber element (106) is arranged at the outlet of the sample delivery channel so as to absorb the oil phase (105) from the stream of oil-separated sample droplets. The oil removal device can be used in two-dimensional separation techniques such as LC-MS, LC-CE, CE-CE etc.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: August 22, 2017
    Assignee: ETH ZURICH
    Inventors: Andrew DeMello, Fiona Pereira, Niu Xize
  • Patent number: 9726002
    Abstract: A water treatment method includes: withdrawing water from the environment; filtering the withdrawn water in a membrane filtration unit; extracting a production flow from an underground formation containing hydrocarbons; separating and collecting production water from the production flow; filtering the production flow in the membrane filtration unit; collecting a treated water flow from the membrane filtration unit. An installation adapted for applying this method is also provided.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: August 8, 2017
    Assignee: Total S.A.
    Inventors: Samuel Heng, Pierre Pedenaud, Philippe Coffin
  • Patent number: 9649598
    Abstract: The invention provides a process for purifying water containing soluble species capable of forming one or more sparingly soluble salts or minerals, said process comprising feeding a pressurized water stream into a treatment zone having one or more membranes disposed therein, passing said stream along said membrane(s) to recover a permeate and to withdraw a concentrate therefrom while periodically reversing the direction of the flow of said stream in said treatment zone, wherein the periodicity of the flow reversal is such that said one or more membranes are exposed to supersaturation conditions evolving in said water stream for a period of time which is less then the time required for said supersaturated water stream to precipitate one or more of said sparingly soluble salts and/or minerals therefrom.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: May 16, 2017
    Assignee: BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
    Inventors: Jack Gilron, Eliyahu Korin
  • Patent number: 9610393
    Abstract: Extracorporeal blood treatment apparatus and methods including a main treatment unit and an auxiliary treatment unit, along with one or more sensors for determining a parameter related to a pressure drop across the auxiliary treatment unit, and a control unit configured to control a flow regulator at least based on the parameter value.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: April 4, 2017
    Assignee: Gambro Lundia AB
    Inventors: Hiram Rada, Nicolas Semenzato
  • Patent number: 9511326
    Abstract: A cycling ultra-thin channel filtration (cUTF) method, system and module are disclosed for concentration and purification of biomolecules. In one embodiment, a cUTF system includes a cUTF module and a cycle controller to load a feed aliquot of a feed stream into the cUTF module inducing permeation of the feed stream to build a boundary layer by pressurizing the feed stream, to stop permeation and to recover a retentate aliquot in a repeating cycle.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: December 6, 2016
    Assignee: SPF TECHNOLOGIES LLC
    Inventor: Gaston de los Reyes
  • Patent number: 9433900
    Abstract: The present invention relates to a process for the production of hydraulic energy by direct osmosis from two saline solutions having different concentrations made to pass through one or more modules of semipermeable membranes having a double inlet and outlet port, originally designed to execute the process of inverse osmosis, without a requirement to realise any technical modification to said modules of membranes. In this manner, an osmotic potential is produced in the membranes creating a current of solution having a pressure sufficient to produce hydraulic energy. A further object of the present invention is the installation designed to produce hydraulic energy according to the stated procedure and the use thereof, together with a desalination plant and a tertiary waste water treatment plant comprising the installation to produce hydraulic energy.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: September 6, 2016
    Assignee: GS INIMA ENVIRONMENT SA
    Inventor: Antonio Ordonez Fernandez
  • Patent number: 9358278
    Abstract: Precipitated bacterial capsular polysaccharides can be efficiently re-solubilised using alcohols as solvents. The invention provides a process for purifying a bacterial capsular polysaccharide, comprising the steps of (a) precipitation of said polysaccharide, followed by (b) solubilisation of the precipitated polysaccharide using ethanol. CTAB can be used for step (a). The material obtained, preferably following hydrolysis and sizing, can be conjugated to a carrier protein and formulated as a vaccine. Also, in vaccines comprising saccharides from both serogroups A and C, the invention provides that the ratio (w/w) of MenA saccharide:MenC saccharide is >1.
    Type: Grant
    Filed: January 20, 2009
    Date of Patent: June 7, 2016
    Assignee: Novartis AG
    Inventor: Paolo Costantino
  • Patent number: 9333285
    Abstract: A method for the depletion of at least one component of a fluid medium includes increasing the concentration of the at least one component to be depleted before its depletion. An apparatus for the depletion of the at least one component of the fluid medium has a concentration increasing unit for increasing the concentration of the component of the fluid medium to be depleted and a depletion unit disposed downstream thereof and in fluid communication therewith for the subsequent reduction in the concentration of the component to be depleted.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: May 10, 2016
    Assignee: FRESENIUS MEDICAL CARE DEUSTSCHLAND GMBH
    Inventor: Andreas Wuepper
  • Patent number: 9320761
    Abstract: An osteogenic composition suitable for use in bone and soft tissue reparative procedures is provided for herein. Methods for preparing osteogenic composition from blood and bone marrow are also provided for. The osteogenic compositions contain therapeutically effective concentrations of one or more osteogenic agents such as BMP-2, TGF-?, PDGF and VEGF.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: April 26, 2016
    Assignee: Vivex Biomedical, Inc.
    Inventors: Hugo Pedrozo, Shuliang Li, Mark Shuster
  • Patent number: 9285354
    Abstract: A method and device for the detection of low-level harmful substances in a large volume of fluid comprising using a concentrator system to produce a retentate and analyzing the retentate for the presence of at least one harmful substance. The concentrator system performs a method comprising pumping at least 10 liters of fluid from a sample source through a filter. While pumping, the concentrator system diverts retentate from the filter into a container. The concentrator system also recirculates at least part of the retentate in the container again through the filter. The concentrator system controls the speed of the pump with a control system thereby maintaining a fluid pressure less than 25 psi during the pumping of the fluid; monitors the quantity of retentate within the container with a control system, and maintains a reduced volume level of retentate and a target volume of retentate.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: March 15, 2016
    Assignee: The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency
    Inventors: Michael V. Carpenter, Lyle G. Roybal, Alan Lindquist, Vincente Gallardo
  • Patent number: 9266060
    Abstract: An air quality control system (AQCS) useful for processing a gas stream, such as a flue gas stream emitted from a fossil fuel fired boiler, for at least partial removal of acidic and like pollutants therefrom. The air quality control system includes a CDS reactor useful using a reducing agent slurry.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: February 23, 2016
    Assignee: ALSTOM Technology Ltd
    Inventor: Mark Albert Fiedler
  • Patent number: 9266066
    Abstract: Asymmetric microporous membranes with localized asymmetries, devices including the membranes, and methods of making and using the membranes, are disclosed. The asymmetric microporous membranes have a first surface and a second surface and an interior bulk defined by the first and second surfaces, wherein the first surface has at least a first region and a second region, the first region having a first porosity comprising a first mean pore size, and the second region having a second porosity comprising a second mean pore size, wherein the ratio of first mean pore size to the second mean pore size is at least about 5:1.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: February 23, 2016
    Assignee: Pall Corporation
    Inventors: Geoffrey Patrick Larue, Xiaosong Wu, Martin Smith
  • Patent number: 9255280
    Abstract: The present invention relates to novel processes for producing ethanol from citrus waste using suitable solvent extractions to reduce the presence of fermentation inhibiting compounds, such as limonene, from citrus waste. The extraction can be performed before or after the polysaccharides present in aqueous mixtures comprising citrus waste are converted into fermentable sugars.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: February 9, 2016
    Assignee: JJ FLORIDA PROPERTIES LLC
    Inventor: Gregory Loyde Hillyer
  • Patent number: 9138663
    Abstract: A method is provided for changing a property of a sample. A sample, comprising particles suspended within a sample fluid, is introduced into a channel which comprises two walls that are permeable to a flow of fluid. A cross-flow is introduced at a predetermined temperature and of a predetermined chemical composition into the channel through a wall. This cross-flow flows at a first velocity and exits in a first direction through the other wall. An imposed field is applied on the particles in a second direction counter to the first direction of the cross-flow. The imposed field causes the particles to migrate at a second velocity opposite and/or equal to the first velocity of the cross-flow. Particles that are approximately balanced by the first and second velocities travel through the channel and are discharged in a fluid of predetermined chemical composition and at the predetermined temperature of the cross-flow.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: September 22, 2015
    Assignee: California Institute of Technology
    Inventors: Richard C. Flagan, Wilton Mui, Andrew J. Downard
  • Patent number: 9133433
    Abstract: The present invention relates to a process and apparatus for purifying a molecule of interest from a heterogeneous clarified fluid mixture. The apparatus of the invention generally comprises a continuous perfusion fermentation system, a continuous particle removal system integrated with the perfusion fermentation system; and a continuous purification system integrated with the particle removal system, which is maintained under sterile conditions. The process comprises filtering a heterogeneous clarified fluid mixture by continuous ultrafiltration at a specific flow rate below the transition point of the molecule of interest in the pressure-dependent region of the flux versus TMP curve, wherein the specific flow rate is maintained substantially constant throughout the continuous ultrafiltration.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: September 15, 2015
    Assignee: Bayer HealthCare LLC
    Inventors: Jens Holger Vogel, Roberto Giovannini, Konstantin B. Konstantinov, Huong My Nguyen, Paul Wu
  • Patent number: 9126853
    Abstract: Disclosed is a fresh water generator for fresh water production, which is effective to prevent a membrane life from becoming worse by suppressing the load on the membrane of a second semi-permeable membrane treatment facility when the concentrated water produced by the treatment of a first semi-permeable membrane treatment facility, and water to be treated with different osmotic pressure there from are mixed and treated with the second semi-permeable membrane treatment facility by the fresh water generator which comprises a means for storing the concentrated water produced from the first semi-permeable membrane treatment facility and water (B) to be treated, which is separately supplied in a storage tank A and a storage tank B in such a manner that the flow rate (mixture ratio) of the concentrated water to the water (B) to be treated is maintained constant, and supplying the concentrated water and the water (B) to be treated from each of the storage tanks to the second semi-permeable membrane treatment facili
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: September 8, 2015
    Assignee: Toray Industries, Inc.
    Inventors: Hironobu Suzuki, Yuji Tanaka, Hiroo Takabatake, Yoshisuke Nakamura
  • Patent number: 9039899
    Abstract: Separation processes using osmotically driven membrane systems are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane. Enhanced efficiency may result from using low grade waste heat from industrial or commercial sources. Pre-treatment and post-treatment may also enhance the osmotically driven membrane processes.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: May 26, 2015
    Assignee: OASYS WATER, INC.
    Inventor: Robert L. McGinnis
  • Patent number: 9023210
    Abstract: An osmotic power generation system and method for generating osmotic power includes a membrane chamber having a semi-permeable membrane therein defining a first portion and a second portion therein. The system also includes a first pump communicating a first fluid to the first portion and a second pump communicating a second fluid to the second portion. The second fluid has higher total dissolved solids than the first fluid. A second portion energy recovery device is in fluid communication with the second portion. A power generator is in communication with the second portion energy recovery device generating electrical power in response to the second portion energy recovery device and the pressure in the second portion.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: May 5, 2015
    Assignee: Fluid Equipment Development Company, LLC
    Inventor: Eli Oklejas, Jr.
  • Patent number: 8969628
    Abstract: The invention relates to a method for enriching a homogenous catalyst from a process flow comprising said homogenous catalyst as a component, wherein the process flow is conducted over at least one membrane and wherein the membrane wholly or partially comprises a polymer that has planar polymer units connected to one another via a rigid link and wherein the linker is contorted, such that at least one planar polymer unit is connected to at least one second planar polymer unit via the link, in a non-co-planar arrangement. The invention furthermore relates to a method for producing tridecanal.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: March 3, 2015
    Assignee: Evonik Degussa GmbH
    Inventors: Markus Priske, Goetz Baumgarten, Hans-Gerd Lueken, Alfred Kaizik, Klaus-Diether Wiese, Uwe Ernst, Patrick Muhlack
  • Patent number: 8940167
    Abstract: The invention relates to a filter assembly for membrane filtration—of liquids, and more in particular a spiral wound filter assembly with improved filtration performance. Provided is a spiral wound filter assembly comprising a permeate channel (5; 305, 325) for transporting permeate to the permeate outlet (12), said permeate channel being provided with at least one flow restriction (13; 113, 120; 213; 333) in form of check or control valves or ridges, for increasing the pressure in at least part of the permeate channel. The invention further relates to an apparatus comprising such a filter assembly, and to methods for using this apparatus.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: January 27, 2015
    Assignee: Friesland Brands B.V.
    Inventors: Albert van der Padt, Tjeerd Jongsma
  • Patent number: 8900458
    Abstract: A separation apparatus using a membrane for diafiltration, which provides precise fractionation of a target substance by monitoring and regulating permeability of the target substance based on measurement values and analytical values indicating separation status, such as physical values and concentration of a permeate liquid, a circulating liquid and an internal circulating liquid in a membrane device. A diafiltration process including adding a cleaning liquid to an treating liquid which contains multiple target substances and extracting a target substance into the permeate liquid supplied from a membrane separation apparatus to fractionate the target substance from other target substances remaining in a residual liquid.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: December 2, 2014
    Assignee: Tsukishima Kankyo Engineering Ltd.
    Inventor: Yasuhiro Tateishi
  • Patent number: 8894858
    Abstract: A method of filtering a feed liquid in a membrane filtration assembly is provided comprising introducing feed liquid to be treated into a filtration chamber of a membrane filtration system including a membrane module having one or more permeable hollow membranes, the module being located in the filtration chamber, and the filtration chamber having an open upper end located above an upper header of the membrane module and a closed lower end, and feed tank surrounding the filtration chamber. The feed tank may be configured to provide the feed liquid through the open upper end of the filtration chamber, and the feed liquid may be applied to the surface of the membranes within the membrane module and withdrawn from the lumens of the membranes as filtrate.
    Type: Grant
    Filed: July 15, 2014
    Date of Patent: November 25, 2014
    Assignee: Evoqua Water Technologies LLC
    Inventors: David John Cox, Warren Thomas Johnson
  • Publication number: 20140339161
    Abstract: A system for ultrafiltration employs a crossflow filtration module for extracting a fraction from a sample fluid (e.g., blood) and a recirculating permeate loop to produce a concurrent permeate flow through the filtration module to maintain a positive transmembrane pressure at all points of the crossflow filter. Permeate in the recirculating loop is enriched by a processing module and stabilized by removing an enriched fraction thereof. In an embodiment, the enriched fraction is concentrated plasma that is returned to a patient.
    Type: Application
    Filed: October 8, 2012
    Publication date: November 20, 2014
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Edward Leonard, Michael Hill, Cees J.M. Van Rijn, Ilan K. Reich, Levy Amar
  • Patent number: 8881600
    Abstract: In a process for testing filters (4) and (13) of treatment fluid of a hemodiafiltration apparatus (1), each filter has a wet semipermeable membrane (5, 14) which separates a gas-filled first chamber (6 and 15) from a liquid-filled second chamber (7 and 16). The first chambers are pressurised by a pump (19) supplying air, while the second chambers are placed in depression by a drainage pump (17) of used dialysis fluid. A first closed system is formed which includes the first chambers and a second closed system is formed which includes the second chambers. Two pressure gauges (P1 and P2) monitor the pressure in the two closed systems for a predetermined time. The monitoring provides indications relating to the filter integrity.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: November 11, 2014
    Assignee: Gambro Lundia AB
    Inventors: Anna Puppini, Renato Pedrazzi, Mauro Suffritti
  • Publication number: 20140326665
    Abstract: An apparatus, for use with a reverse osmosis system comprising a feed input, a concentrate output, and a permeate output, includes (i) at least one pressure sensor operative to measure a pressure of at least the permeate output of the reverse osmosis system and to generate a signal indicative of the pressure of at least the permeate output of the reverse osmosis system and (ii) at least one controller operative to adjust a speed of at least a first pumping mechanism based at least in part on the signal indicative of the pressure of at least the permeate output of the reverse osmosis system. The first pumping mechanism comprises at least one of: (i) a fluid input coupled to at least the permeate output of the reverse osmosis system; and (ii) a fluid output coupled to at least the feed input of the reverse osmosis system.
    Type: Application
    Filed: May 3, 2013
    Publication date: November 6, 2014
    Applicant: Crestron Electronics, Inc.
    Inventor: George Feldstein
  • Publication number: 20140326666
    Abstract: Apparatus and methods are provided for removing solids from wastewater. The apparatus may include a dissolved solids removal system including a first membrane stack for removing a first portion of dissolved solids from wastewater, the first membrane stack having a first rejection rate and including at least one first membrane having a first operating pressure rating. A first solution unit may be included downstream of the at least one first membrane, the first solution unit being configured to maintain a differential pressure over the at least one first membrane below the first operating pressure rating. The dissolved solids removal system may also include a final membrane stack for removing a final portion of dissolved solids from the wastewater, the final membrane stack being located downstream of the first membrane stack and having a final rejection rate higher than the first rejection rate.
    Type: Application
    Filed: May 3, 2013
    Publication date: November 6, 2014
    Applicant: HYSSOP BRANCH, LLC
    Inventors: Bob R. Drew, David Potter
  • Patent number: 8864996
    Abstract: This invention relates to a process for producing a product stream with improved reduction of Conradson Carbon Residue (“CCR”) and a reduced average boiling point from a heavy hydrocarbon feedstream utilizing a high-pressure, low-energy separation process. The invention may be utilized to reduce the CCR content and reduce the average boiling point in heavy hydrocarbon feedstreams, such as whole crudes, topped crudes, synthetic crude blends, shale oils, bitumen, oil from tar sands, atmospheric resids, vacuum resids, or other heavy hydrocarbon streams. This invention also results in a process with an improved CCR separation efficiency while maintaining permeate flux rates.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: October 21, 2014
    Assignee: Exxonmobil Research and Engineering Company
    Inventors: Daniel P. Leta, Edward W. Corcoran, Brian Erik Henry, James D. Dearth, Kirk C. Nadler, Stephen M. Cundy, Miroslav Petro, Thomas H. McWaid, Li Song, Yan Ying Chan
  • Patent number: 8840790
    Abstract: Systems and methods of controlling fouling during a filtration procedure are described. A plasmapheresis method includes accepting a selection of a plasma flow rate and predicting an estimated procedure end time based at least partially on a plasma collection target volume. The method also includes flowing blood past a membrane and changing a plasma flow rate until the selected plasma flow rate through the membrane is achieved. The method also includes determining an acceptable rate of pressure change with time for respective times to the estimated procedure end time, the acceptable fouling rate limit being associated with a system pressure and adjusting the plasma flow rate based on the determined acceptable rate of pressure change with time.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: September 23, 2014
    Assignee: Fenwal, Inc.
    Inventors: Christopher J. Wegener, Marc N. Weasler, Benjamin E. Kusters, Daniel R. Boggs, Kyungyoon Min
  • Patent number: 8834719
    Abstract: A dialysis machine method includes in an embodiment applying a pneumatic closing pressure to a first valve chamber and arranging a compliance chamber to flex and absorb energy from the pneumatic closing pressure so as to tend to prevent the pneumatic closing pressure from opening an existing closure of a second valve chamber.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: September 16, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Robert W. Childers, Thomas D. Kelly, Rodolfo Roger