Abstract: Described is a closure adapted to be fit on top of containers such as bottles. In various embodiments, the closure may include an outer skirt and an inner skirt. The closure may be engageable with a container neck. In some embodiments, a region of weakness may be adapted to break and/or deform upon an attempt to remove the closure from the container neck. In some embodiments, after the break and/or deformation, the closure may no longer be engageable with the container neck.

Abstract: Anti-filling device to be attached to the neck of a bottle to be closed by a sealing cap, including attachment means for attachment to the bottleneck, a chamber including a lower lip surrounding a lower orifice and confining a moveable part which forms a valve in conjunction with the lower lip, and an axial distribution duct. The device further includes a moveable axial rod, secured to the anti-filling device, the axial movement of which relative to the device is limited between a low position and a high position, and at least one stopper which is in engagement with the moveable axial rod such that, when the moveable axial rod is located in the low position, the stopper shuts an orifice which is arranged in the chamber. The low position is imposed by a projection attached to the cap, which comes into contact with the moveable axial rod when the cap is attached to the bottleneck.

Abstract: A method for filling and using an infusion bag useful in medicinal and related applications. The infusion bag comprises a bladder having at least two ports, an inlet port and an outlet port. The inlet port includes a valve which can be moved to an open position for filling of the bladder and then moved to a closed position to seal the bladder. The outlet port communicates with a catheter or the like.