Abstract: A stent for vascular interventions having a hybrid open cell geometry. Variants of the stent include bare metal stents and drug-eluting stents. Embodiments of the stent include end projections for radiopaque markers or a discontinuous partial radiopaque coating on low-stress or low-strain regions of the peripheral stent. The stents of the invention are characterized by having thin walls, nested rows of struts, high expansion ratio, high and uniform radial force over entire diametric size and length of device, crush resistance up to and including about 90% of its fully expanded diameter, high fatigue resistance and high corrosion resistance.

Abstract: A pressure vessel has a first end with a first boss, the first boss having a first outer surface. The vessel includes a liner having a second outer surface, a shell disposed over the second outer surface, and a first vent. The first vent is formed onto at least a portion of the first outer surface and at least a portion of the second outer surface. The first vent includes a texture that provides a higher rate of gas flow through the first vent than through a portion of an interface of the liner and shell lacking the texture. In another aspect, a pressure vessel has a first end and a second end, a plurality of first longitudinal vents and a plurality of second longitudinal vents. At least one of first longitudinal vents is circumferentially offset around the pressure vessel from at least one of the second longitudinal vents.

Abstract: A pressure vessel has a first end with a first boss, the first boss having a first outer surface. The vessel includes a liner having a second outer surface, a shell disposed over the second outer surface, and a first vent. The first vent is formed onto at least a portion of the first outer surface and at least a portion of the second outer surface. The first vent includes a texture that provides a higher rate of gas flow through the first vent than through a portion of an interface of the liner and shell lacking the texture. In another aspect, a pressure vessel has a first end and a second end, a plurality of first longitudinal vents and a plurality of second longitudinal vents. At least one of first longitudinal vents is circumferentially offset around the pressure vessel from at least one of the second longitudinal vents.

Abstract: An improvement in drug-eluting stents, and method of their making, are disclosed. The surface of a metal stent is roughened to have a surface roughness of at least about 20 ?in (0.5 ?m) and a surface roughness range of between about 300-700 ?in (7.5-17.5 ?m). The roughened stent surface is covered with a polymer-free coating of a limus drug, to a coating thickness greater than the range of surface roughness of the roughened stent surface.

Abstract: The inventive concepts relate to an apparatus and a method for etching a substrate, a stamp for etching a substrate, and a method for manufacturing the stamp. The method for etching a substrate includes bringing a substrate into contact with a stamp including a pattern on which a metal catalyst is formed, and etching the substrate by a chemical reaction between the metal catalyst and an etching solution.

Abstract: A method of making organic light emitting diode array includes following steps. A base having a number of first electrodes on a surface of the base is provided. A first organic layer is located on the surface of the base to cover the number of first electrodes. A first organic light emitting layer is applied on the first organic layer. A template with a first patterned surface with a number of grooves with different depths is provided. The template is attached on the first organic light emitting layer and separated from each other, wherein a number of protruding structures with different heights is formed. A second organic light emitting layer is deposited on a part of the plurality of protruding structures. A second organic layer is located on the organic light emitting layer. A second electrode is applied to electrically connect to the second organic layer.

Abstract: A method and system for integrated circuit fabrication is disclosed. In an example, the method includes determining a first process parameter of a wafer and a second process parameter of the wafer, the first process parameter and the second process parameter corresponding to different wafer characteristics; determining a variation of a device parameter of the wafer based on the first process parameter and the second process parameter; constructing a model for the device parameter as a function of the first process parameter and the second process parameter based on the determined variation of the device parameter of the wafer; and performing a fabrication process based on the model.

Abstract: A method for manufacturing a gravure plate includes, setting a certain measurement area on a surface of the gravure plate, finding at least one of a spatial volume that is the total of the volume of a space formed by a plurality of cells located in the measurement area and an average depth obtained by dividing the spatial volume by a surface area of the measurement area, and adjusting, based on a relationship between at least one of the spatial volume and the average depth and an application thickness of a printing material after printing, at least one of the spatial volume and the average depth so as to fall within at least one of a specified value range for the spatial volume and a specified value range for the average depth determined in accordance with a target value range for the application thickness.

Abstract: A regular metallic, cylindrical tubular needle cannula (1) is subjected to a metal etching liquid (5) in the inside lumen (11) thereby increasing the inside diameter and enhancing the flow properties while maintaining the outside appearance. The inside diameter is only increased over a controlled length (14) of the full length of the needle cannula (10) leaving sufficient length and wall thickness to also taper the outside diameter if so wanted.

Abstract: A medical device for surgical implantation adapted to serve as a drug delivery system has one or more drug loaded holes with barrier layers to control release or elution of the drug from the holes or to control inward diffusion of fluids into the holes. The barrier layers are non-polymers and are formed from the drug material itself by beam processing. The holes may be in patterns to spatially control drug delivery. Flexible options permit combinations of drugs, variable drug dose per hole, multiple drugs per hole, temporal control of drug release sequence and profile. Methods for forming such a drug delivery system are also disclosed. Gas cluster ion beam and/or accelerated Neutral Beam derived from an accelerated gas cluster ion beam may be employed.

Abstract: A microfluidic mixer including one or more mixer channels, each of the mixer channels having at least one glass surface on which are formed protrusions arranged in a herringbone pattern.

Abstract: The present invention provides a flow-channel device for detecting light emission, which suppresses a noise originating in unnecessary light emission, and can be simply bonded with the use of an organic material. The flow-channel device having a flow channel is structured by the bonding of at least two substrates, wherein at least any one substrate has a first groove which constitutes the flow channel, and a second groove for arranging an adhesive therein which contains an organic material, and a light-shielding layer is provided on an inner wall of the second groove so as to block a light emitted from the second groove from penetrating into the first groove.

Abstract: The present invention discloses a thin film multi-band antenna, which is formed by PVD-Roll to Roll process and is formed of metal-oxide, conductive polymer, conductive glue or CNT. In another aspect, the present invention discloses a manufacturing method of thin film antenna, comprising preparing gel, followed by coating the gel on a substrate to form a transparent thin film. Thermal process is performed to heat the thin film. The gel includes vinyl oxide and metal compounds, wherein the vinyl oxide includes PEO having In(NO)3.3H2O, In(Ac)3, SnCl2.2H2O, or Sn(C2O4) contained thereof.

Abstract: This is structure and method for providing a textured surfaced that can be used in a plurality of systems including ink jet printing. In ink jet printing, the textured surface of this invention controls ink drawback and significantly improves image quality. The textured surface has an average roughness, Ra, of about 0.2 to 1.5 microns, a texture density of about 104-107 pits per cm2, a texture size of about 0.5-5 microns, and a texture depth of about 0.5-10 microns.

Abstract: A method of coating a peripheral surface of a sleeve core with a radiation curable coating liquid including the steps of: supporting a sleeve core in a vertical position coaxial with a coating axis; providing an annular coating collar, supplying the coating liquid to the annular coating collar and moving the annular coating collar along the sleeve core in a vertical direction coaxial with the coating axis, thereby coating a layer of the coating liquid onto the peripheral surface of the sleeve core; wherein the coated layer of the coating liquid is cooled by the peripheral surface of the sleeve core to have a viscosity at the temperature of the peripheral surface of the sleeve core and at a shear rate of 10 s?1 which is larger than a minimum viscosity ?min, with: ? min = d 2 50 wherein d represents the thickness of the coated layer expressed in ?m, and ?min is expressed in mPa·s. Also, a coating device for performing the above coating method.

Abstract: A method of a forming a hollow, drug-eluting medical device includes providing composite member having an outer member and a core member disposed within a lumen of the outer member. The composite member is shaped into a pattern. Openings are formed through the outer member of the composite member. The composite member is processed to remove the core member from the lumen of the outer member without harming the outer member, leaving a hollow tubular member already formed into the desired pattern. The lumen of the outer member is filled with a therapeutic substance.

Abstract: The fragrance slurry pad receives a fragrance in slurry and prints the slurry into a recognizable logo, brand, or word upon a strip. To enhance the marketing impact of fragrance strip advertising and to differentiate among marketers without increase in cost, the present invention is fragrance slurry deposition pads that support and reinforce a marketing message. The preferred embodiment has a brand name, logo, or message etched into a flexographic print pad. The print pad applies the slurry to a strip located beneath a flap. Upon opening the flap, the fragrance slurry appears in a discernible pattern and visible message.

Abstract: To provide an optical element having excellent adhesion to a lamination film, a roller nanoimprint apparatus, and a production method of a mold roller are disclosed. In at least one embodiment of the present invention, an optical element includes a nanostructure film including recesses and protrusions in nanometer size formed continuously on a surface of the nanostructure film and a lamination film laminated on the nanostructure film. The nanostructure film includes a nanostructure-free region free from the recesses and protrusions in nanometer size in both ends along a longitudinal direction of the nanostructure film.

Abstract: An intravascular stent especially suited for implanting in curved arterial portions or ostial regions. The stent can include an end region which is fabricated to have a greater radial strength than the remaining axial length of the stent. Such a stent is particularly suited for use in ostial regions, which require greater support near the end of the stent. The stent alternatively can include sections adjacent the end of the stent with greater bending flexibility than the remaining axial length of the stent. Such a stent is particularly suited for use in curved arteries. The stent can also be constructed with an end that has greater radial strength and sections adjacent the end with greater bending flexibility. Such a stent prevents flaring of the stent end during insertion.

Abstract: Provided is a method of producing a printing plate, especially a gravure plate with cushion properties, which enables direct gravure printing on a hard printing target without using a blanket roll owing to being provided with cushion properties, effects a satisfactory gravure printing on a rough surface such as corrugated cardboard, and is suitable for color-printing a matrix image for forming a color filter on glass for liquid crystal panels or an image on a compact disk or the like. The gravure plate includes a hollow roll provided on the surface thereof with a cushion layer formed of rubber or resin with cushion properties, a copper-plated layer formed on the surface of the cushion layer and formed on the surface thereof with multiple gravure cells, a metal layer formed on the surface of the copper-plated layer, a metal carbide layer formed on the surface of the metal layer, and a diamond-like carbon film for covering the surface of the metal carbide layer.

Abstract: A novel gravure engraving roll that has a surface-reinforcing coating layer being nontoxic and having no danger of pollution generation at all and that excels in printing life; and a process for producing the same. There is provided a gravure engraving roll comprising: a metal hollow roll; a copper plating layer superimposed on the surface of the hollow roll and on its surface furnished with a multiplicity of gravure cells; a metal layer superimposed on the surface of the copper plating layer; a layer of carbide of said metal superimposed on the surface of the metal layer; and a diamond-like carbon coating covering the surface of the metal carbide layer.

Abstract: A nozzle structure is provided comprising a monolithic body having an array of nozzles. The nozzles having openings with sectional openings having heights of about 100 nm or less. The nozzles are generally associated with one or more well structures.

Abstract: The stamp (10) for a lithographic process, such as patterning a surface layer, of the invention has a stamp body (5) with at least a first recess (11) formed therein, which recess defines a first aperture (15) in the printing face (3) of the stamp (10). The first recess (11) narrows with increasing distance to the printing face, while any cross-section of the first recess, when perpendicularly projected on the printing face (3), will lie within the aperture (15). The printing face may comprise small (11, 12) and large apertures (13) as well as small surfaces (14) in between apertures, while it is nevertheless able to produce prints which are accurate replicas of the printing face. Even details on a submicron scale can be adequately printed. The stamp (10) can be manufactured by a method which comprises anisotropic etching of a first body to make a mold and replicating the mold in the printing face (3) of the stamp (10).

Abstract: An aspect of the present invention comprises a unique method of manufacturing and tracking storage vial, tubes, trays, and other containers used in the life and clinical science industries, through the use of 2d, linear, binary, or other alphanumeric information etched into the storage containers. Another aspect of the present invention is a storage container having identifying information etched thereon with a laser. Yet another aspect of the present invention comprises an in-house etching station for a biological or chemical manufacturer/supply company, for creating customer specified identifiers on the storage containers.

Abstract: An implantable medical device, such as a stent or graft, having asperities on a designated region of its outer surface is disclosed. The asperities can serve to improve retention of one or more layers of a coating on the device and to increase the amount of coating that can be carried by the device. The asperities can be formed by using a stream of pressurized grit to roughen the surface. The asperities can also be formed by removing material from the outer surface, for example, by chemical etching with or without a patterned mask. Alternatively, the asperities can be formed by adding material to the outer surface, for example, by welding powder particles to the outer surface or sputtering.

Abstract: A magnet roller includes a rotary sleeve having a given systematic pattern on the outer surface of the sleeve and a magnet provided in the sleeve. This structure transfers toner uniformly along the outer surface of the sleeve. A printer, for instance, employing this magnet roller can print a fine copy.

Abstract: In order to simplify the sequence of creating a mask, in particular for producing a printing plate, and at the same time to improve the quality of the printing plate produced by means of a mask, the use of laser-induced thermal transfer is provided. The structure information is applied directly to the surface of a printing plate carrier during the creation of a mask, by means of a thermal transfer film and a laser image-setting unit, so that by means of the structure information applied, differentiation with regard to image points and non-image points can be carried out directly in order to produce a printing plate.

Abstract: The subject invention relates to a stent with respect to which the occurrence of artifacts in nuclear spin tomography can be reduced or avoided. The subject invention also pertains to the etching of stents, incorporating titanium and/or titanium alloys, that have been processed with tools containing magnetizing components. The subject invention can also be useful for the control of in-stent-restenosis by allowing imaging under nuclear spin tomography to see in-stent-restenosis in the interior of the subject stent.

Abstract: An implantable medical device, such as a stent or graft, having asperities on a designated region of its outer surface is disclosed. The asperities can serve to improve retention of one or more layers of a coating on the device and to increase the amount of coating that can be carried by the device. The asperities can be formed by using a stream of pressurized grit to roughen the surface. The asperities can also be formed by removing material from the outer surface, for example, by chemical etching with or without a patterned mask. Alternatively, the asperities can be formed by adding material to the outer surface, for example, by welding powder particles to the outer surface or sputtering.

Abstract: A microneedle array module is disclosed comprising a multiplicity of microneedles affixed to and protruding outwardly from a front surface of a substrate to form the array, each microneedle of the array having a hollow section which extends through its center to an opening in the tip thereof. A method of fabricating the microneedle array module is also disclosed comprising the steps of: providing etch resistant mask layers to one and another opposite surfaces of a substrate to predetermined thicknesses; patterning the etch resistant mask layer of the one surface for outer dimensions of the microneedles of the array; patterning the etch resistant mask layer of the other surface for inner dimensions of the microneedles of the array; etching unmasked portions of the substrate from one and the other surfaces to first and second predetermined depths, respectively; and removing the mask layers from the one and the other surfaces.

Abstract: Disclosed herewithin is an apparatus for fabricating a stent which involves processing a tubular member whereby no connection points to join the edges of a flat pattern are necessary. The process includes the steps of: a) preparing the surface of a tubular member, b) coating the outside surface of the tubular member with a photo-sensitive resist material, c) placing the tubular member in an apparatus designed to simultaneously rotate the tubular member while passing a specially configured photographic frame negative between a light source and the tubular member, d) exposing the tubular member to a photoresist developer, e) rinsing the excess developer and uncured resist from the exposed tubular member, f) sealing the inner lumen of the tubular member, and g) treating the tubular member with a chemical or electro-chemical process to remove uncovered metal. By modifying the photographic negative, this process can be employed to fabricate a virtually unlimited number of stent designs and configurations.

Abstract: It is an object of the present invention to provide a processing method for preventing elution of lead in a lead-containing copper alloy to prevent lead from eluting from a faucet metal, etc. made of a lead-containing copper alloy, and a drinking water service fitting made of a lead-containing copper alloy in which elution of lead has been prevented. By forming a chromate film on the surface of a lead-containing copper alloy material, it is possible to reduce elution of the lead left in a limited amount on the surface. A drinking water service fitting made of a lead-containing copper alloy is immersed in an alkaline etching solution in a pre-processing step for a nickel chromium plating step to selectively remove lead on the surface of the lead-containing copper alloy material and is then activated in a solution such as sulfuric acid and hydrochloric acid.

Abstract: This invention is directed to an intracorporeal device formed of a high strength Co—Ni—Cr alloy and is particularly suitable for forming a composite product with a pseudoelastic member formed of NiTi alloy. Suitable intracorporeal products include guidewires and stents. The high strength alloy consists essentially of about 28 to about 65% cobalt, about 2 to about 40% nickel, about 5 to about 35% chromium, up to about 12% molybdenum, up to about 20% tungsten, up to about 20% iron and the balance inconsequential amounts of impurities and other alloying constituents, with a preferred alloy composition including about 30 to about 45% cobalt, about 25 to about 37% nickel, about 15 to about 25% chromium and about 5 to about 15% molybdenum. Intravascular devices such as guidewires, stents and the like can be formed of this high strength Co—Ni—Cr alloy.

Abstract: A prosthesis for implantation in a blood vessel includes struts with a cross-section having a flat base with angled edges on the inner surface and chamfered edges on the outer or exterior surface. The base angled edge is substantially a right angle, while the outer or exterior surface has edges that are chamfered with either round or angled chamfers. The chamfers could be manufactured by either machining the chamfer into the stock material, or by tumbling the stent in a tumbler to abrasively wear the edges to form a chamfer.

Abstract: A micro-lithographic apparatus and method for selectively exposing/masking resist material on a non-planer workpiece or filamentary substrate includes a hollow, energy transparent tubular member with a hollow for containing the workpiece. The tubular member is selectively coated with a layer of energy-opaque material to form the desired pattern. The transparent tube and opaque coating selectively expose/mask the resist material on the workpiece. Alternatively, the apparatus and method include an energy opaque tubular member with apertures formed through the walls of the tubular member. The apertures form the desired pattern. The opaque tube with apertures selectively exposes/masks the resist material. The apparatus and method may also include an energy source and a rotating device for rotating the tubular member, with the workpiece disposed therein, to the energy source or rotating energy source around tubular member or have energy source surround tubular member.

Abstract: An implantable prosthesis, for example a stent, is provided having one or more micropatterned microdepots formed in the stent. Depots are formed in the prosthesis via chemical etching and laser fabrication methods, including combinations thereof. They are formed at preselected locations on the body of the prosthesis and have a preselected depth, size, and shape. The depots can have various shapes including a cylindrical, a conical or an inverted-conical shape. Substances such as therapeutic substances, polymeric materials, polymeric materials containing therapeutic substances, radioactive isotopes, and radiopaque materials can be deposited into the depots.

Abstract: The invention describes a capillary optical element with a complex structure of capillaries and a method for its manufacture. To achieve uniform transmission, for example, a lens can be used as a capillary optical element which has a complex structure with channels of different diameter. The channels with the smaller diameter operate effectively at higher energies, channels with intermediate diameters are intended for an intermediate energy range, whereas channels with a large diameter are used in a low energy range. A lens can consist, for example, of three zones: channels with small diameter are used in the central zone, channels with intermediate diameters are used in the intermediate annular zone, and the peripheral zone has channels of large diameters. The number of zones can arbitrary. In addition, a technical process for manufacturing the complex capillary structures is described.

Abstract: The invention relates to a method for making a relief strip, comprising the steps of etching the strip, causing the etched strip to pass through a coloring line, a silicone solution metering unit, to meter a silicone solution on the strip etched portion, introducing the strip into a mold having a plurality of mold cavities of different cross-sections and spacings, therefrom a vacuum metered ink amount is ejected and caused to enter the recess of the material, and causing the strip to further pass through an infrared oven, and finally brushing the strip.

Abstract: Disclosed herewithin is an apparatus for fabricating a stent which involves processing a tubular member whereby no connection points to join the edges of a flat pattern are necessary. The process includes the steps of: a) preparing the surface of a tubular member, b) coating the outside surface of the tubular member with a photo-sensitive resist material, c) placing the tubular member in an apparatus designed to simultaneously rotate the tubular member while passing a specially configured photographic frame negative between a light source and the tubular member, d) exposing the tubular member to a photoresist developer, e) rinsing the excess developer and uncured resist from the exposed tubular member, f) sealing the inner lumen of the tubular member, and g) treating the tubular member with a chemical or electro-chemical process to remove uncovered metal. By modifying the photographic negative, this process can be employed to fabricate a virtually unlimited number of stent designs and configurations.

Abstract: The present invention relates to a method for producing a mold having a micro-textured surface, wherein the mold can be used to form an elastomeric seal having a micro-textured surface. The resulting seal will hold an amount of lubricant that is released with time, the release of the lubricant will result in decreased friction between the seal and a surface contacted by the seal.

Abstract: A process of manufacturing a roll punch used for forming the partition walls on the rear panel of a PDP is disclosed. In the process of this invention, a forming roll is primarily coated with a mask on its external surface. The mask is, thereafter, partially removed from the forming roll, thus forming a plurality of regularly spaced mask-free parts on the forming roll. The forming roll is, thereafter, etched at the mask-free parts using ultrasonic waves within an etching tank, and so a desired roll punch having partition wall forming grooves is produced. This manufacturing process enlarges the width of the lands between the forming grooves of the roll punch, thus allowing an easy arrangement of address electrodes on the rear panel of a PDP. It is also possible to produce a desired highly precise roll punch by properly adjusting the intervals between the mask-free parts of the forming roll.

Abstract: A generally tubular device (e.g., a stent or catheter) for placement in a lumen of a patient's body is made by forming a depressed pattern in an external surface of a mold. The depressed pattern corresponds to a desired shape of the generally tubular device. A material is deposited in the depressed pattern for the material to form the generally tubular device conforming to the depressed pattern. The generally tubular device is separated from the mold.

Abstract: A micro-miniature gas chromatograph column is fabricated by forming matching halves of a circular cross-section spiral microcapillary in two silicon wafers and then bonding the two wafers together using visual or physical alignment methods. Heating wires are deposited on the outside surfaces of each wafer in a spiral or serpentine pattern large enough in area to cover the whole microcapillary area inside the joined wafers. The visual alignment method includes etching through an alignment window in one wafer and a precision-matching alignment target in the other wafer. The two wafers are then bonded together using the window and target. The physical alignment methods include etching through vertical alignment holes in both wafers and then using pins or posts through corresponding vertical alignment holes to force precision alignment during bonding. The pins or posts may be withdrawn after curing of the bond.

Abstract: A process for producing lithographic features in a substrate layer is is described, comprising the steps of lowering a stamp (15) carrying an reactant (14) onto a substrate (10), confining the subsequent reaction to the desired pattern, lifting said stamp and removing the debris of the reaction from the substrate. Preferably, the stamp carries the pattern to be etched or depressions corresponding to such a pattern. Using the described methods, patterns with submicron features can be generated. The method allows a general solution to parallel handling and transfer of materials in a variety of technical fields.

Abstract: A process for manufacturing photopolymer blocks, which are first exposed to UVA radiation and mounted on printing cylinders to in combination form a printing sleeve for carrying out printing in flexography and in dry offset, includes a series of automated steps for manufacturing the printing sleeves. A device for implementing the process includes a series of stations, arranged in line, one after the other, including a storage magazine for receiving the exposed printing sleeves, a solvent-vapor lock, an etching device, a drying device and a storage station for receiving the completed printing sleeves.

Abstract: An improved method of producing a diamond tube by chemical vapor deposition and a hollow support mandrel used therein. The method comprises depositing a diamond film on an outer side of the hollow mandrel by the CVD process. The mandrel is then etched away by subjecting an inner side of the mandrel to the etching action. It was unexpectedly discovered that the etch time is drastically reduced by using the hollow mandrels.

Abstract: Manufacturing processes for apparatus, including slotted hypotube, for use as a catheter, a guidewire, a catheter sheath for use with catheter introducers or a drug infusion catheter/guidewire are disclosed. The manufacturing process includes creating a pattern of slots or apertures in a flexible metallic tubular member, by processes including but not limited to, electrostatic discharge machining (EDM), chemical milling, ablation and laser cutting. These slots or apertures may be cut completely or partially through the wall of the flexible metallic tubular member. These manufacturing processes may include the additional step of encasing the flexible metallic member such that a fluid tight seal is formed around the periphery of the tubular member.

Abstract: A two-wafer microcapillary structure is fabricated by depositing boron nitride (BN) or silicon nitride (Si.sub.3 N.sub.4) on two separate silicon wafers (e.g., crystal-plane silicon with [100] or [110] crystal orientation). Photolithography is used with a photoresist to create exposed areas in the deposition for plasma etching. A slit entry through to the silicon is created along the path desired for the ultimate microcapillary. Acetone is used to remove the photoresist. An isotropic etch, e.g., such as HF/HNO.sub.3 /CH.sub.3 COOH, then erodes away the silicon through the trench opening in the deposition layer. A channel with a half-circular cross section is then formed in the silicon along the line of the trench in the deposition layer. Wet etching is then used to remove the deposition layer. The two silicon wafers are aligned and then bonded together face-to-face to complete the microcapillary.