Abstract: A fluid dispensing container is provided. The container includes a container body formed from a first flexible material defining an interior cavity. The container includes a membrane formed from a second flexible material and a seal coupling the membrane to the inner surface of the container body. The membrane divides the interior cavity into a contents chamber and a dispensing chamber, and the membrane and the seal are configured to be fluid tight to maintain fluid within the contents chamber prior to rupture of the membrane. The rupture stress of the second flexible material is less than the rupture stress of the first flexible material such that, as fluid pressure within the contents chamber increases, the membrane is configured to rupture without the container body rupturing.

Abstract: A container assembly includes a container body having a side wall encircling an axis, and a metal end for attachment to an upper edge of the side wall via heat-sealing. The outer peripheral region is shaped prior to application to the container body such that an annular channel is defined between an inner chuck wall and an outer chuck wall of the metal end. The metal end is pushed straight onto the side wall such that the upper edge of the side wall is received into the channel. The surfaces of the side wall and the opposing surfaces of the chuck walls have heat-sealable material thereon. The metal end is heated to melt and fuse the heat-sealable layers, thereby sealing the metal end onto the side wall. The metal end is shaped such that the free edge of the outer chuck wall is not exposed.

Abstract: The present invention relates to a rigid plastics-material internal container (12) from a thermoplastic plastics material for a pallet container (10) or a similar large-volume retainer for storing and for transporting liquid or free-flowing filling materials, having a flexible inliner (28) from a thin-walled plastics-material or composite-material film that is inserted into the rigid plastics-material internal container (12). For filling and removal at the base, the thin-walled inliner (28) at the base side has at least one filling and removal connector (42), said filling and removal connector (42) at the front being fixedly welded into a corresponding filling and removal connector (32) at the base side of the rigid plastics-material internal container (12).

Abstract: The present invention relates to a flexible tank wherein liquid can be stored and which can transport liquid from one location to another location by means of a vehicle and having a lower compartment and an upper compartment positioned one above the other. As an improvement, said flexible tank comprises at least one tank body formed by at least one flexible wall joined in a manner forming a flexible pipe-like form and at least one folding region having at least one first folding line and at least one second folding line provided such that a passage throttle is defined in between.

Abstract: A collection liner for a medical or a surgical operation includes a closed flexible bag portion. The closed flexible bag portion has a width direction (W) and a length direction (L). The closed flexible bag portion includes an upper part of the bag portion in the length direction and a lower part of the bag portion in the length direction. The lower part of the bag portion is folded inside the upper part of the bag portion in such a manner that the entire lower volume of the lower part is upside down inside the upper part.

Abstract: A flavoring condiment sauce for food comprised of about 19%-21% lemon juice, about 19%-21% water, about 12%-14% minced garlic, about 12%-14% butter or margarine, about 12%-14% onion, about 0.15%-0.5% Abodo sauce, about 2%-3% garlic powder, about 0.15%-0.5% seasoning salt, about 6%-8% black pepper, about 1%-2% crushed red pepper, and about 8%-10% Accent salt.

Abstract: A flexible pouch for two-component products includes a front panel, a back panel and a pair of side seals. An upper compartment is formed between the front panel, the back panel, one of the pair of side seals, an intermediate side seal and a bottom frangible seal. A lower compartment is formed beneath the upper compartment between the front panel and the back panel. A vertical passage extends between the intermediate side seal and another of the pair of side seals from the lower compartment to an opening. Rupture of the bottom frangible seal provides a fluid passageway from the upper compartment to the lower compartment.

Abstract: Embodiments include a package for containing and dispensing a product. The package includes first and second layers; a product seal zone where the first layer is joined to the second layer, the product seal zone having an inner perimeter that defines an unsealed pouch area for containing the product and an outer perimeter; and a header zone adjacent to the outer perimeter of the product seal zone. The header zone includes a first tab; a second tab; a first tab-cut in the first layer within an unsealed portion of the header zone; and a second tab-cut in the second layer within the unsealed portion of the header zone. Other embodiments are also included herein.

Abstract: A container body of the sheet container is composed of a sheet member given by lamination of a plurality of film layers, and has a plurality of surface-like parts; the plurality of surface-like parts include a first surface-like part and a second surface-like part that adjoin and cross each other; the sheet member has a filler enclosing part in which a filler is enclosed between the plurality of film layers; the filler enclosing part includes an intermediate extending part laid across the first surface-like part and the second surface-like part, and a first adjoining part and a second adjoining part that individually adjoin both sides of the intermediate extending part; and the intermediate extending part extending more further from the second surface-like part than the first adjoining part and the second adjoining part extend.

Abstract: There is provided a 3D printing build material container (1). The container (1) comprises a reservoir (3) and a reinforcement structure (4). The reservoir is to hold build material. The reinforcement structure is attached to the reservoir at at least one selected location. The reservoir and reinforcement structure are to permit reconfiguration of the container from a relatively flat configuration to an in-use configuration in which the reservoir is tillable with build material.

Abstract: An elongated tubular housing adapted to receive an adjustable external compression device introduced on one end of the tubular housing distal from the opening releasing the contents, and retained in position by a member engaging a grooved strip that is integrated with and/or retained on the housing surface material with a strip surface of like material, providing a reliable, economic and functional outer compression member retention apparatus and method. Further embodiments according to the present invention include a dispenser having regions provided for ease and comfort of gripping, grooved strip end-stop to retain compression device, and grooved strip dimensional and placement details to provide functional, manufacturable and economic material dispenser.

Abstract: The invention disclosed herein is a system for dispensing storage or fogging oil into the cylinders of internal combustion engines prior to putting the engines up for storage, during storage, or when removing the engine from storage. The system includes a dispensing adapter for closing off the spark plug hole of an engine cylinder, the dispensing adapter including threads of different sizes and diameters to accommodate common spark plug thread sizes. The dispensing adapter may also be used to temporarily plug a spark plug hole when a spark plug is removed from an engine.

Abstract: Disclosed herein are embodiments of hydration bladders that include flexible wall portions along with relatively more rigid structural portions that are shaped to help define the shape of the bladder and can also help a user grip and manipulate the bladder. The structural portions can also support or incorporate other bladder features, such as inlet ports, caps, outlet ports, valves, tubes, attachment points, graphic designs, and/or other features. Some embodiments include an outlet tube that is retractable and extendable through an upper port at the top of the bladder.

Abstract: A dispensing system, a flexible bag or pouch for use therewith, and methods for filling a dispensing bottle with a flowable product and dispensing the same are disclosed. The system includes a flexible bag and a dispensing bottle. The flowable product is located in the bag. The bag includes a first end and a second end. The bottle includes an interior chamber, a squeezable sidewall surrounding the chamber and a bottom cap including a dispensing valve. The bag is disposed in the chamber with the second end opened to form an open mouth, whereupon the flowable product is in communication with the dispensing valve. Squeezing of the bottle's sidewall applies pressure to the flowable product to cause it to be dispensed out of the bottle through dispensing valve.

Abstract: Improvements in a single serve point of consumption beverage dispensing valve is disclosed. The valve includes a fresh water input fitting, a carbonated water inlet fitting a vacuum pump that transfers concentrated from a flavor bullet and diffuses the concentrate with water an optionally carbonation to provide a consistent mixture. The flavor bullet manifold is self-cleaning to eliminate flavor cross-contamination. An initiation lever starts the mixing, diffusion and dispensing that is monitored and controlled with a micro water flow metering system that controls flow solenoids and dispensing of the mixed beverage.

Abstract: The laminated tube container has a tube body that includes a light blocking layer between an innermost layer and an outermost layer made of resin. The tube body has a butted portion in which both side edges of a laminated sheet constituting the tube body butt against each other and a reinforcing tape portion provided on an inner surface of the tube body along the butted portion. The reinforcing tape portion has a pair of resin layers and an intermediate layer that includes an aluminum layer and is disposed between the pair of resin layers.

Abstract: A flexible pouch for receiving flowable products that includes a fitment having a spout to allow the flowable products to be discharged from the pouch. The flexible pouch is formed from a top and a bottom web of material. A sealant strip is attached to a top edge of each of the top and bottom webs of material. A fitment having a canoe and spout is positioned such that the canoe is positioned between the first and second sealant strips. The height of the canoe and the width of the first and second sealing strips are the same to minimize the amount of sealant material. The first and second sealant strips are sealed to each other along the entire width of the flexible pouch to entrap the canoe of the fitment between the top and bottom webs.

Abstract: The application relates to a pouch assembly (100) containing a liquid being an aqueous urea solution for use in a selective catalytic reduction system for treating the exhaust gases of an internal combustion engine of a vehicle and for transferring the liquid to a liquid tank of the vehicle from the outside of the liquid tank, the pouch assembly (100) comprising a flexible pouch (1) and a spout (2) attached thereto having a base (21) extending axially through an opening (111) provided in a wall of the pouch (1) and being attached to the opening (111), a top end (22) being configured for insertion in the inside passage of the filling neck (3) of the liquid tank during the filling of the liquid tank, and a body (23) that extends between the base (21) and the top end (22) of the spout (2), the body (23) having an elongated shape, and the body (23) at least partially extending in the inside passage of the filling neck (3) of the liquid tank during the filling of the liquid tank, the base (21), the top end (22) an

Abstract: Embodiments include a package for containing and dispensing a product. The package includes first and second layers; a product seal zone where the first layer is joined to the second layer, the product seal zone having an inner perimeter that defines an unsealed pouch area for containing the product and an outer perimeter; and a header zone adjacent to the outer perimeter of the product seal zone. The header zone includes a first tab; a second tab; a first tab-cut in the first layer within an unsealed portion of the header zone; and a second tab-cut in the second layer within the unsealed portion of the header zone. Other embodiments are also included herein.

Abstract: A force detector includes a support, fluid bags, a contact portion, a detector, and a computer. The contact portion is opposite to a side on which the fluid bags are in contact with the support and is adjacent to the fluid bags. The computer obtains information regarding the internal pressures of the fluid bags from the detector. Upon application of an external force to the contact portion from an object, the computer calculates a force acting in a tangential direction on a contact surface between the object and the contact portion based on a difference between the internal pressures of the fluid bags.

Abstract: A tube for dispensing product includes a closed first end, an open second end opposing the closed first end, and a side wall extending between the closed first end and the open second end. The side wall and the closed first end define an interior portion to hold product. The side wall of the tube includes internal threads extending inwardly from the side wall adjacent to the open second end. The various elements of the tube may include interlocking features to seal the tube from outside fluids.

Abstract: The application relates to a pouch assembly (100) for containing a liquid being an aqueous urea solution for use in a selective catalytic reduction system for treating the exhaust gases of an internal combustion engine of a vehicle and for transferring the liquid to a liquid tank of the vehicle from the outside of the liquid tank, the pouch assembly (100) comprising a flexible pouch (1) and a spout (2) attached thereto having a base (21) extending axially through an opening (111) provided in a wall of the pouch (1) and being attached to the opening (111), a top end (22) being configured for insertion in the inside passage of the filling neck (3) of the liquid tank of the vehicle during the filling of the liquid tank, and a body (23) that extends between the base and the top end (22) of the spout (2), the body (23) having an elongated shape, and the body (23) at least partially extending in the inside passage of the filling neck (3) of the liquid tank during the filling of the liquid tank, the base (21), the t

Abstract: Methods and devices for orally administering fluids and medical instrumentation to individuals for the promotion of health are disclosed. An apparatus is described comprising a cartridge including a cartridge body defining a reservoir and a cartridge spout extending proximally from the cartridge body and terminating at an aperture. A cartridge seal is attached to a proximal tip of the cartridge spout, wherein the cartridge seal hermetically seals the liquid within the cartridge, and wherein the cartridge seal is detachable from the proximal tip of the cartridge spout and permanently coupled to the cartridge at a location distal to the cartridge spout. A proximal cartridge seal portion is positioned proximal to the location of permanent coupling and is moveable away from the cartridge aperture once the cartridge seal is detached from the proximal tip of the cartridge spout.

Abstract: The beauty or skin-care treatment may be a single use system for providing a manicure or pedicure treatment or other beauty or skin-care service. Each primary packaging that may be provided with the beauty or skin-care treatment may contain a beauty or skin-care product that may be used in providing the treatments. The beauty or skin-care treatment may include multiple primary packages in the form of single-serve packaging provided collectively as a set. The set may be housed in the secondary packaging and packaged together to form a multi-step treatment. The beauty or skin-care products contained in the single-serve packaging may be made of ingredients beneficial to the skin and may include products to aid in sanitizing, exfoliating, nourishing, hydrating and moisturizing the skin.

Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.

Abstract: A method of manufacturing a seamless, non-wicking containment bladder includes providing yarn materials, coating the yarn materials with a precursor protective coating, loading the yarn materials into an additive manufacturing process, depositing the yarn materials in pre-selected amounts and locations to form a desired structure, forming and heat-setting, and coating the seamless bladder.

Abstract: A squeeze tube includes a fluid-discharge container and a fluid-discharge closure mated to the fluid-storage container. The fluid-discharge closure is coupled to one end of the fluid-storage container and configured to discharge selectively fluid stored in a product-storage region formed in the fluid-storage container.

Abstract: The present disclosure provides a cutlery dispenser for dispensing wrapped cutlery. The cutlery dispenser may include a case configured to expand from a compact configuration into an expanded configuration. The cutlery dispenser also may include a wrapped cutlery band disposed within the case and configured to be dispensed therefrom. The present disclosure also provides a method for dispensing wrapped cutlery. The method may include the step of providing a cutlery dispenser including a case and a wrapped cutlery band disposed within the case. The method also may include the step of expanding the case from a compact configuration into an expanded configuration. The method further may include the step of dispensing at least a portion of the wrapped cutlery band from the case.

Abstract: The present disclosure provides a flexible pouch. In an embodiment, the flexible pouch includes opposing flexible films. The opposing flexible films define a common peripheral edge. The flexible pouch includes a microcapillary strip sealed between the opposing flexible films. A first side of the microcapillary strip is located at a first side of the common peripheral edge. A second side of the microcapillary strip is located at a second side of the common peripheral edge. A peripheral seal extends along at least a portion of the common peripheral edge. The peripheral seal includes a sealed microcapillary segment.

Abstract: The invention firstly relates to a print head of a continuous ink jet printer, comprising a first reservoir (12) and a second reservoir (22), arranged on either side of least one jet ejection nozzle (30, 301-30n) to which they are connected, and a first actuator (16, 161-16n) for applying a 1st pressure to the ink of the, or coming from the, 1st reservoir, and a second actuator (26, 261-26n) for applying a 2nd pressure to the ink of the, or coming from the, 2nd reservoir, and a controller for controlling these first and second actuators, said controller being programmed to apply a variable difference between these 2 pressures.

Abstract: A package having a sanitary dispenser is depicted and described. The package generally includes a dispenser that is sealed from environmental contaminants by a feature or portion of the package. The sealed dispenser portion of the package is accessed prior to use and the user is able to access the contents of the package through the sanitary dispenser. The dispenser may be inverted prior to use and deployed prior to use. A frangible portion may be provided to the dispenser. The dispenser may be re-sealable in the package. A straw may further be provided to the dispenser and be deployable by the user for access to the package contents.

Abstract: A combination of a container made out of rolled laminated plastic or rolled laminated metal, combined with a child-resistant locking assembly between the container and a cap removably affixed to the container. The container includes a closed rear end, a front wall and a flexible sidewall between the closed rear end and the front. The cap includes a central post inserted into a dispensing opening in a dispensing nozzle of the contain to reduce the possibility of contents in the container seeping out of the dispensing nozzle after the sealing cap is affixed to the nozzle.

Abstract: Various embodiments of pressure regulated beverage cartridges are disclosed. In some embodiments, a system includes a cartridge and a beverage preparation machine. The cartridge and machine can be configured such that, when the cartridge is received in the machine, a pressure of less than a limit value is maintained in the cartridge during the beverage preparation process, which can improve the flavor of certain beverages, such as brewed coffee beverages.

Abstract: A container is provided to contain a liquid to be used in a liquid dispenser that is space-saving and enables checking of the amount of remaining liquid, a refilling operation, and maintenance to be readily performed. A stock solution container in which a concentrated stock solution is to be contained and that is to be used in a beverage dispenser to eject a beverage constituted by the concentrated stock solution and a diluent includes: a containing portion having a bag shape and is to contain the concentrated stock solution; and an ejecting portion for ejecting the concentrated stock solution to the outside, the ejecting portion being provided to protrude from the containing portion. An ejection port is provided at a leading end of the ejecting portion, and the concentrated stock solution is ejected from the ejection port as the containing portion deforms based on an external force.

Abstract: A pouring nozzle is made from a packaging laminate film which is excellent in the tear-opening property and improves lowering of a liquid draining property in pouring. A method forms a tear-inducing flaw for opening a packaging laminate film suitable for use in a package bag for housing and keeping a liquid packed material. A pouring nozzle is made from a packaging laminate film having a laminate structure of not less than three layers including a base film layer and non-oriented sealant layers laminated on front and rear surface sides of the base film layer and having a pouring path at its central portion. A tear-inducing flaw is formed by irradiating a laser beam across the pouring path and to a position where a portion of at least one of the non-oriented sealant layers on the front and rear surface sides of the base film layer is displaced by pushing.

Abstract: A fluid monitoring assembly includes a segment of tubing having a wall defining a lumen through which the fluid passes and a sensor at least partially embedded within a wall of the tubing. The assembly includes a housing having first and second portions connected to one another at a hinge, the housing defining an interior portion configured to hold the segment of tubing and the sensor. The housing may be opened and closed as needed using a fastener.

Abstract: A package bag made by a packaging laminate film and provided midway between both side portions with a back-lined portion and a filling space of a liquid packing material, wherein the back-lined portion is sealed on its peripheral edge with an outer edge seal part, an inner edge seal part, an upper edge seal part and a lower edge seal part, while an internal side of these seal parts is defined by a partition wall of these seal parts into a self-supporting stable portion and a pouring path communicating to a pouring port disposed in the outer edge seal part; and the inner edge seal part is provided with a first easy-peelable portion separating the self-supporting stable portion and the filling space and a second easy-peelable portion separating the pouring path and the filling space, and the first easy-peelable portion is preferentially peeled by pushing the filling space.

Abstract: An apparatus and method for inserting prosthesis implants into a patient pocket. The apparatus has three openings including a prosthesis opening and two implant insertion openings. The apparatus prevents infection; eases insertion and placement; and reduces complications. In use, the first implant insertion end of the bellow is placed through the patient incision while allowing the bellow to be manipulated to force the first implant into a surgical pocket of a patient. Then the bellow is rotated 180 degrees so that the second implant insertion end becomes the opening through which the second implant is inserted into the second incision while allowing the bellow to be manipulated to force the second implant into a surgical pocket.

Abstract: A squeezable container is disclosed for holding and dispensing a flowable product like yogurt. The container generally includes a flexible and collapsible pouch body having an internal space for storing the flowable product, an external spout fitment attached to the outside of the dispensing end of the pouch body and through which the product can be dispensed, and a cap on the spout fitment, which can be opened by the user to dispense the product and closed to reseal the container. The cap includes a self-closing valve, and is configured to support the container in a cap-down orientation.

Abstract: A reclosable flexible package is described that includes an inner film layer, an outer film layer laminated to the inner film layer, and reclose region defined in a portion of package film layers. The reclose region includes pressure sensitive adhesive disposed between the inner and outer film layers. A number of cut lines are provided in the outer film layer in the reclose region, such that the user, by manipulating the package film layers at the reclose region, can reveal the underlying layer of pressure sensitive adhesive. Once the pressure sensitive adhesive of the reclose region is exposed, the action of the user can serve to adhere the pressure sensitive adhesive to itself and/or other portions of the film, such that the package is cinched in the area of the reclose region and maintains the remnants of the package contents within the reclosed package for later use.

Abstract: A flexible package including a package body including a first side-surface film and a second side-surface film sealed in a peripheral portion. The package body has sealed portions formed in side edge portions such that a non-sealed portion is formed in at least one of the sealed portions. The non-sealed portion has a gas injection portion containing a gas which has a specific heat at constant volume of 0.67 kJ/kg·deg or higher at 0° C. and 1 atm. The gas injection portion has a diameter of from 3 to 50 mm and is formed such that a repelling force is from 4 to 30 N at 23° C. and 1 atm when an entire gas injection portion is nipped from both sides of the first and second side-surface films and squeezed until a nipped gas injection portion has a width equal to a half of the diameter of the gas injection portion.

Abstract: A container for pourable foodstuffs has a base, a side wall connected to the base and surrounding a storage chamber. An elastic cuff is connected with a first end to the side wall and has a second end with an opening. The cuff width decreases from first to second end along a longitudinal container axis. The elastic cuff can be pushed into and pulled out of the storage chamber. A sealing element shaped as a stopper can be inserted into the opening for closing the container and has a shank portion matched in shape and size to the opening such that sealing abutment of a shank portion surface against surfaces of the elastic cuff adjoining the cuff opening is established in a contact region of the shank portion when the stopper is inserted. The shank portion has an end with a thickened portion thicker than the contact region.

Abstract: A fluid monitoring assembly includes a segment of tubing having a wall defining a lumen through which the fluid passes and a sensor at least partially embedded within a wall of the tubing. The assembly includes a housing having first and second portions connected to one another at a hinge, the housing defining an interior portion configured to hold the segment of tubing and the sensor. The housing may be opened and closed as needed using a fastener.

Abstract: A metering valve assembly for closing the housing of an aerosol generator includes a valve body (3) provided with a transfer chamber (31) in which is housed a valve (5) movable between a closed position and an open position, and a reservoir (4) in contact with the transfer chamber, constituted by a rigid wall (41), a flexible membrane (42), a planar peripheral edge (411) for attaching the flexible membrane and a bottom wall (413) inside the peripheral edge. A spring element (43) inside the reservoir is constituted by a curved plate having a convex face toward the flexible membrane and designed to deform toward the bottom wall (413) and to allow the flexible membrane (42) to move closer to the rigid wall when the valve is in the open position and to return to its initial shape as soon as the valve returns to the closed position.

Abstract: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

Abstract: A device for packaging and dispensing pasty products, includes a rigid bottle (1) bearing a pump body (2) mounted on a ring (3) that is fixed in the neck of the rigid bottle (1), having a lower peripheral annular stop rib (8) that engages with a clip-fastening collar (12) borne by the pump body in order to fix the pump body (2) to the ring (3). This ring (3) is secured to the neck of a pouch (4) that has a deformable and flexible wall and contains the product to be dispensed, the pump body (2) bearing, above the clip-fastening collar (12), a seal (5) accommodated in an annular groove (6) in the pump body. At least the stop rib or the clip-fastening collar (8, 12) is provided with at least one vent hole (11).

Abstract: A food container is disclosed that includes a food compartment and a seal-on cover. The food compartment has an outer rim that circumscribes a volume. The food compartment outer rim has tear tab guides that extend outward from the rim. The seal-on cover has a peripheral edge with two portions, the first portion is connected to the rim and the second portion is not connected to the rim and extends past the outer rim forming an overhang. The extended tear tab guides are located adjacent to the overhang and direct the user as to where the tear line begins at the overhang and extends to an opposite side of the peripheral edge. When a user pulls on the overhang, the seal-on cover tears along the tear line and exposes a portion of the volume.

Abstract: The device for containing fluid substance to be dispensed by manually operated pump, for associating with a rigid container neck, includes a bag having body and neck from which connection flange extends transversally, and a ring cap including bag first connector having an annular connection body, presenting a longitudinal symmetry axis. The annular connection body has a lower portion having a diameter smaller than the bag flange external diameter, and bigger than or equal to the bag neck external diameter; and an upper portion having an annular seat open on the top, having a rest surface lying horizontally for the connection flange. The connection body includes a substantially cylindrical wall and a guide element to guide at least a portion of the flange from a lower free edge of the connection body to the annular seat and prevent the flange (4) from slipping out of the annular seat.

Abstract: A patterned thermoplastic elastomer (TPE) film for fabricating a liquid-filled blister, has a blister-sized cavity in fluid communication with a microfluidic channel via a gating region.

Abstract: A drug delivery device (50) is provided comprising a drug reservoir (10) and a piston (11). The drug reservoir (10) is provided for comprising a drug and comprises a flexible wall (22) and a dispensing hole (15) for dispensing the drug into an environment of the drug de delivery device (50). The piston (11) is provide for pressing against the flexible wall (22) to compress the drug reservoir (10) for pushing an amount of the drug through the dispensing hole (15). An adhesion interface (51) between a surface of the piston (11) and the flexible wall (22) prevents sliding between the surface of the piston (11) and the flexible wall (22).