Flow And Pressure Controlled Patents (Class 236/24.5)
  • Patent number: 6451603
    Abstract: The invention consists of a non-naturally occurring nucleic acid molecule capable of blocking or interfering with a replicative intermediate of a virus, a virusoid, or a viroid. The nucleic acid molecule may contain a ribozyme or a plurality of ribozymes. Alternatively, the nucleic acid molecule may be an antisense nucleic acid molecule. The ribozyme may be a hairpin ribozyme, a hammerhead ribozyme, an RNAase P ribozyme, a minizyme, or other catalytic RNA molecule. The virus may be an animal, a mammalian, a plant, a fungal, a protozoan, a yeast, a bacterial virus, or a human virus. The nucleic acid molecule may be expressed in the cell or it may be preformed and administered ex vivo. The present invention contemplates methods of controlling infection of a pathogenic infectious agent in a plant or animal.
    Type: Grant
    Filed: March 2, 1995
    Date of Patent: September 17, 2002
    Assignee: Gene Shears Pty. Limited
    Inventors: David G. Atkins, Wayne L. Gerlach, Mark J. Young