With Positron Source Patents (Class 250/363.03)
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Patent number: 12153175Abstract: A method for processing positron emission tomography data is provided, this method includes: obtaining a first coordinate and a second coordinate respectively corresponding to two ends of a response line to be processed; determining corresponding dimensional coordinates of the response line to be processed in a sinogram based on the first coordinate and the second coordinate; and generating the sinogram corresponding to the response line to be processed based on the dimensional coordinates. According to this method, the amount of calculation of system matrix is reduced, the accuracy of position information of the generated response line is improved, and the accuracy of generated sinogram is improved accordingly.Type: GrantFiled: May 25, 2022Date of Patent: November 26, 2024Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCESInventors: Zhanli Hu, Yongfeng Yang, Chunhui Zhang, Zhonghua Kuang, Xiaohui Wang, San Wu, Dong Liang, Xin Liu, Hairong Zheng
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Patent number: 12131410Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an imaging method (100). The method includes: receiving imaging data on a frame by frame basis for frames along an axial direction with neighboring frames overlapping along the axial direction wherein the frames include at least a volume (k) and a succeeding volume (k+1) at least partially overlapping the volume (k) along the axial direction; and generating an image of the volume (k) using an iterative image reconstruction process in which an iteration of the iterative image reconstruction process includes: computing a local penalty function for suppressing noise over the volume (k) including reducing the value of the local penalty function in an overlap region; generating an update image of the volume (k) using imaging data from the volume (k) and further using the local penalty function.Type: GrantFiled: November 15, 2019Date of Patent: October 29, 2024Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Andriy Andreyev, Xiyun Song, Ravindra Mohan Manjeshwar
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Patent number: 12100117Abstract: A computer-implemented method is disclosed for image stitching for a plurality of digital images of an infrastructure surface for defect detection. The method includes providing a plurality of partial digital images of an infrastructure surface. The method includes extracting global positioning system meta-data from data corresponding to the partial digital images. The method includes determining feature descriptions of features in the one or more partial digital images. The method includes executing a scheduled processing sequence for the partial digital images based on the extracted global positioning system meta-data including determining an affinity matrix using the feature descriptions of adjacent partial digital images to incrementally position each of the partial digital images such that an overview image of the infrastructure surface is produced by iteratively digitally stitching the plurality of partial digital images together.Type: GrantFiled: March 15, 2021Date of Patent: September 24, 2024Assignee: International Business Machines CorporationInventors: Florian Michael Scheidegger, Dhruti Nilesh Shah, Adelmo Cristiano Innocenza Malossi
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Patent number: 12086990Abstract: A system and method for simultaneous imaging of multiple positron emission tomography (PET) tracers in which digital data including PET information associated with at least two time points is received, where the digital data is generated by PET scans of a region of interest of a physiologic body which has been administered at least two PET tracers that differ from one another at least in their radioactive decay constant. At least one set of output digital data is determined based on the radioactive decay constants of each PET tracer, the at least one set of output digital data corresponding to at least one of the at least two PET tracers. The determination of at least one set of output digital data includes at least one of regularizing to account for statistical noise, preconditioning the digital data to be more amenable to signal separation, applying feature preservation techniques, or accounting for late tracer kinetics.Type: GrantFiled: April 23, 2024Date of Patent: September 10, 2024Assignee: MultiFunctional Imaging LLCInventor: Dan J. Kadrmas
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Patent number: 12078766Abstract: A device for the detection of gamma rays presents a high resolution in the three-dimensional position of the impact of the gamma ray within one or more scintillation crystal blocks coupled to an array of photosensors, for the determination of the impact energy of said gamma ray, the determination of the instant in time when said impact occurred, the interaction depth and the determination of the time-of-flight. Advantageously, in said device, the scintillation crystal detection blocks are optically isolated, in such a way that the scintillation light can only exit said blocks via the output region; and the scintillation crystal detection blocks and the array of photosensors are disposed in direct optical coupling.Type: GrantFiled: January 20, 2021Date of Patent: September 3, 2024Assignees: UNIVERSITAT POLITECNICA DE VALENCIA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Jose Maria Benlloch Baviera, Antonio Javier Gonzalez Martinez, Victor Ilisie, John Barrio Toala, Efthymios Lamprou
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Patent number: 12020447Abstract: A non-transitory recording medium storing a computer readable program that causes a computer to perform position aligning, accuracy calculating, and image combining. The position aligning is performing position alignment of other frame images with respect to one reference frame image selected from among multiple frame images that form a dynamic image. The accuracy calculating is calculating an accuracy of the position alignment for each pixel of each of the other frame images. The image combining is combining the reference frame image with the other frame images after the position alignment to generate one composite still image. In the image combining, the computer performs weighting and generates the one composite still image, the weighting being processing of changing a composition ratio between the other frame images for each pixel according to the accuracy calculated by the accuracy calculating.Type: GrantFiled: May 26, 2021Date of Patent: June 25, 2024Assignee: KONICA MINOLTA, INC.Inventor: Haruhiko Miyazaki
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Patent number: 11995824Abstract: Systems and methods for determining at least one correction parameter for a Positron Emission Tomography (PET) scanner including a plurality of detector units is provided. For each of the plurality of detector units, the methods may include determining, based on scan data of one or more scans of a phantom at a plurality of positions, a first sum of coincidence events detected by the detector unit. The methods may further include determining a second sum of coincidence events that are expected to be detected by the detector unit and determining, based on the first sum of coincidence events and the second sum of coincidence events, at least one correction parameter associated with the detector unit. The phantom may be moved to the plurality of positions along an axis of a field of view of the PET scanner during the one or more scans.Type: GrantFiled: May 7, 2020Date of Patent: May 28, 2024Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Songsong Tang, Yong Zhao, Xin Fan
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Patent number: 11963813Abstract: A PET imaging system, with parallel detector rings sharing a common axis (e.g., rings with one or more detector elements in the axial direction and two or more detector elements in the transaxial direction), may have an adaptive axial and/or transaxial FOV by employing a sparse detector configuration and adapting the size of axial gaps between rings and/or the size of transaxial gaps between detector elements in each ring. The axial FOV may be dynamic, enabling PET data acquisition in multiple modes (e.g., “retracted” with detector rings in a compact configuration, and “extended” with detector rings extended for longer axial FOV). The transaxial FOV may be dynamic, enabling an adaptive detector ring diameter for different body part contours. The sparse detector ring configurations may be used to extend the scanner axial and/or transaxial FOV, or retain the current system's FOV with half the number of (or otherwise fewer) detector elements.Type: GrantFiled: December 12, 2019Date of Patent: April 23, 2024Assignee: CORNELL UNIVERSITYInventors: Sadek Nehmeh, Nikolaos A. Karakatsanis
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Patent number: 11925498Abstract: The present disclosure relates to reconstructing an image.Type: GrantFiled: September 29, 2020Date of Patent: March 12, 2024Assignee: Shenyang Intelligent Neuclear Medical Technology Co., Ltd.Inventors: Rumei Zhang, Long Yang, Peng Gao, Guodong Liang, Jun Zhang
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Patent number: 11867841Abstract: One example device comprises a plurality of emitters including at least a first emitter and a second emitter. The first emitter emits light that illuminates a first portion of a field-of-view (FOV) of the device. The second emitter emits light that illuminates a second portion of the FOV. The device also comprises a controller that obtains a scan of the FOV. The controller causes each emitter of the plurality of emitters to emit a respective light pulse during an emission time period associated with the scan. The controller causes the first emitter to emit a first-emitter light pulse at a first-emitter time offset from a start time of the emission time period. The controller causes the second emitter to emit a second-emitter light pulse at a second-emitter time offset from the start time of the emission time period.Type: GrantFiled: December 29, 2022Date of Patent: January 9, 2024Assignee: Waymo LLCInventors: Michael Marx, Pierre-Yves Droz
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Patent number: 11854450Abstract: A display device includes a display panel including a plurality of pixels, a data driver configured to provide data signals to the plurality of pixels, a scan driver configured to provide scan signals to the plurality of pixels, and a controller configured to control the data driver and the scan driver. The controller includes a volatile age memory configured to store accumulated degradation amounts for the plurality of pixels, and an internal age memory configured to store backup accumulated degradation amounts generated based on the accumulated degradation amounts. The controller is further configured to compensate input image data by selectively using the accumulated degradation amounts of the volatile age memory or the backup accumulated degradation amounts of the internal age memory.Type: GrantFiled: July 20, 2021Date of Patent: December 26, 2023Assignee: SAMSUNG DISPLAY CO., LTD.Inventors: Jongman Kim, Hyungkeun Park
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Patent number: 11816815Abstract: A computer-implemented method for provision of a correction algorithm for an x-ray image that was recorded with an x-ray source emitting an x-ray radiation field, a filter facility spatially modulating an x-ray radiation dose, and an x-ray detector is provided. The correction algorithm includes a trained first processing function that, from first input data that includes at least one first physical parameter describing the x-ray radiation field and/or the measurement and at least one second physical parameter describing the spatial modulation of the filter facility, determines first output data. The first output data includes a mask for brightness compensation with regard to the spatial modulation of the filter facility in the x-ray image. The method includes providing first training data, providing an autoencoder for masks, and training of the autoencoder using the first training data. The method also includes determining an assignment rule, and providing the trained first processing function.Type: GrantFiled: June 21, 2022Date of Patent: November 14, 2023Assignee: Siemens Healthcare GmbHInventors: Sai Gokul Hariharan, Heiko Rohdjeß
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Patent number: 11755062Abstract: A processing system includes a digital processing unit programmable as a function of a firmware stored to a non-volatile memory and a resource connected to the digital processing unit via a communication system. The processing system also includes a time reference circuit including a first digital counter circuit to generate, in response to a clock signal, a system time signal including a plurality of bits indicative of a time tick-count, and a time base distribution circuit to generate a time base signal by selecting a subset of the bits of the system time signal, wherein the time base signal is provided to the resource. The resource detects a given event, stores the time base signal to a register in response to the event, and signals the event to the digital processing unit. The digital processing unit reads, via the communication system, the time base signal from the register.Type: GrantFiled: September 20, 2022Date of Patent: September 12, 2023Assignee: STMICROELECTRONICS APPLICATION GMBHInventor: Rolf Nandlinger
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Patent number: 11733410Abstract: A method for detecting potential faults in a cooling system that cools a detector electronic assembly (DEA) of a positron emission tomography (PET) imaging system having a plurality of PET detector rings each including a plurality of PET detectors having an associated DEA. The method includes verifying continuity of coolant lines in a coolant flow path of a DEA and calculating a flow rate through a coolant flow path of a DEA. Selected circuit board temperature sensors are used to detect temperature values that serve as surrogates for temperature change of a coolant. Further, the selected temperature sensors are located on hardware that is replicated on different points or locations on the flow path such that the temperature sensors have similar performance characteristics and are of like kind.Type: GrantFiled: November 9, 2020Date of Patent: August 22, 2023Assignee: Siemens Medical Solutions USA, Inc.Inventor: John Keller
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Patent number: 11707243Abstract: Multiple interactions, such as Compton scattering, inside a PET detector are used to predict an incident photon's direction for identifying true coincidence events versus scatter/random coincidence events by creating a cone shaped shell projection defining a range of possible flight directions for the incident photon. The disclosed techniques can be used as prior information to improve the image reconstruction process. The disclosed techniques can be implemented in a LYSO/SiPM-based layer stacked detector, which can precisely register multiple interactions' 3D position.Type: GrantFiled: April 14, 2021Date of Patent: July 25, 2023Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Liang Cai, Wenyuan Qi, Xiaochun Lai, Peng Peng
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Patent number: 11704846Abstract: The disclosure relates to a system and method for image reconstruction. The method may include the steps of: obtaining raw data corresponding to radiation rays within a volume, determining a radiation ray passing a plurality of voxels, grouping the voxels into a plurality of subsets such that at least some subset of voxels are sequentially loaded into a memory, and performing a calculation relating to the sequentially loaded voxels. The radiation ray may be determined based on the raw data. The calculation may be performed by a plurality of processing threads in a parallel hardware architecture. A processing thread may correspond to a subset of voxels.Type: GrantFiled: June 7, 2021Date of Patent: July 18, 2023Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yang Lv, Yu Ding
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Patent number: 11592585Abstract: The present disclosure relates to a PET detector and a PET frame. The PET detector may include a plurality of detector modules and a plurality of installing modules configured to install the plurality of detector modules. The plurality of installing modules may be coupled together to form a detector ring. The PET frame may include a detector stabilizing cylinder configured to stabilize a detector and a fixing support configured to support the detector stabilizing cylinder. The detector stabilizing cylinder may be rotatably fixed on the fixing support.Type: GrantFiled: April 18, 2022Date of Patent: February 28, 2023Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Huawei Jiang, Huaifang Jiang
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Patent number: 11557188Abstract: A system, device and method facilitate accurate detection of gunshot events through spectrum analysis of impulse signals and/or evaluating impulse signal exponential decay amplitude and time values. In various embodiments, the device and system employ an acoustic sensor, one or more high-pass and low-pass filters, a threshold detector, a differentiator, a decay waveform shape generator, one or more comparators and one or more timers to facilitate detection of gunshot events and/or components of gunshot events.Type: GrantFiled: April 7, 2022Date of Patent: January 17, 2023Assignee: Halo Smart Solutions, Inc.Inventors: David Antar, Paul Galburt, Frank L. Jacovino, David Rayna
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Patent number: 11529108Abstract: A positron emission tomography (PET) technique that can enhance the image resolution and system sensitivity of a clinical PET/CT scanner for imaging a whole body or a target region of a subject is provided. The system includes a detector array and a detector panel. The detector array includes an array of gamma ray detectors defining a field of view of a scanner and configured to detect at least one coincidence event. The detector panel includes an array of gamma ray detectors having a higher intrinsic spatial resolution than the detector array and positioned in closer proximity to a patient table than the detector array. The detector panel is positioned outside the field of view defined by the detector array during at least a portion of scanning by the PET system. The detector panel is configured to detect at least one coincidence event in cooperation with the detector array.Type: GrantFiled: November 27, 2019Date of Patent: December 20, 2022Assignee: Washington UniversityInventors: Yuan-Chuan Tai, Joseph O'Sullivan, Ke Li, Qiang Wang
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Patent number: 11428829Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100) to reconstruct list mode data acquired over a frame acquisition time using a plurality of radiation detectors (17) in which the events of the list mode data is timestamped.Type: GrantFiled: January 30, 2019Date of Patent: August 30, 2022Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Xiyun Song, Chuanyong Bai, Jinghan Ye, Andriy Andreyev, Zhiqiang Hu
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Patent number: 11402521Abstract: An imaging system based on an imaging device and/or a cooling system is provided. The imaging system may include a control module, an imaging device, and/or a cooling system. The imaging device may include a first portion and a second portion. The cooling system may include a cooling module configured to generate a cooling medium, and/or a cooling medium passage configured to spread the cooling medium. The cooling medium passage may belong to a closed loop. At least part of the cooling system may be located within the imaging device such that the cooling medium may be in direct contact with the at least part of the imaging device.Type: GrantFiled: November 25, 2019Date of Patent: August 2, 2022Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Weiping Liu, Yixing Sun
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Patent number: 11385362Abstract: The invention provides a novel arrangement of photon sensors on a scintillation-crystal based gamma-ray detector that takes advantage of total internal reflection of scintillation light within the scintillation detector substrate. The present invention provides improved spatial resolution including depth-of-interaction (DOI) resolution while preserving energy resolution and detection efficiency, which is especially useful in small-animal or human positron emission tomography (PET) or other techniques that depend on high-energy gamma-ray detection. Moreover, the new geometry helps reduce the total number of readout channels required and eliminates the need to do complicated and repetitive cutting and polishing operations to form pixelated crystal arrays as is the standard in current PET detector modules.Type: GrantFiled: October 26, 2017Date of Patent: July 12, 2022Assignee: Arizona Board of Regents on behalf of the University of ArizonaInventors: Lars Furenlid, Xin Li
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Patent number: 11382586Abstract: Systems and methods are provided for evaluating tissue for abnormal glucose uptake within a region of interest within a patient. A PET scanner obtains PET imagery including the region of interest and at least part of the liver. An SUV calculator calculates a first set of SUVs representing the region of interest and a second set SUVs representing the liver from the set of at least one PET image. A standardization component calculates a correction value as a function of the second set of SUVs and applies the correction value to either a decision threshold associated with the region of interest or the first set of SUVs. A diagnosis component compares the first set of SUVs to the decision threshold to determine if the glucose uptake within the region of interest is abnormal. A display provides the determination to a user.Type: GrantFiled: August 14, 2015Date of Patent: July 12, 2022Inventor: Richard R. Black
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Patent number: 11324472Abstract: A method of estimating energy-based scatter content in PET list-mode data is provided.Type: GrantFiled: June 16, 2020Date of Patent: May 10, 2022Assignee: Siemens Medical Solutions USA, Inc.Inventor: James Hamill
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Patent number: 11322333Abstract: A scintillator assembly including an entrance surface for receiving charged particles into the scintillator assembly, the charged particles including first charged particles at a first energy level and second charged particles at a second energy level. A first scintillator structure configured for receiving the first charged particles and generating a corresponding first signal formed of first photons with a first wavelength of ?1, a second scintillator structure configured for receiving the second charged particles and generating a corresponding second signal of second photons with a second wavelength of ?2, and an emitting surface for egress of a combined signal from the scintillator assembly, the combined signal including the first and second photons, and at least one beam splitter for receiving the combined signal and separating the combined signal to first and second photons.Type: GrantFiled: May 6, 2021Date of Patent: May 3, 2022Assignee: EL-MUL TECHNOLOGIES LTDInventors: Dmitry Shur, Eli Cheifetz, Armin Schon
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Patent number: 11311255Abstract: Medical detectors and medical imaging devices are provided. In one aspect, a medical detector includes: a photoelectric conversion device, a first crystal array layer disposed over the photoelectric conversion device, and a second crystal array layer disposed over the first crystal layer. The first crystal array layer includes a plurality of first scintillation crystals arranged in a first crystal array, and a first coupling medium being filled between every adjacent two of the first scintillation crystals. The second crystal array layer includes a plurality of second scintillation crystals arranged in a second crystal array, and a second coupling medium being filled between every adjacent two of the second scintillation crystals. A light transmittance of the second coupling medium is different from a light transmittance of the first coupling medium.Type: GrantFiled: July 17, 2020Date of Patent: April 26, 2022Assignee: Shanghai Neusoft Medical Technology Co., Ltd.Inventors: Xi Wang, Xinying Li, Jian Zhao, Baowei Xu, Guodong Liang
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Patent number: 11307316Abstract: The present disclosure relates to a PET detector and a PET frame. The PET detector may include a plurality of detector modules and a plurality of installing modules configured to install the plurality of detector modules. The plurality of installing modules may be coupled together to form a detector ring. The PET frame may include a detector stabilizing cylinder configured to stabilize a detector and a fixing support configured to support the detector stabilizing cylinder. The detector stabilizing cylinder may be rotatably fixed on the fixing support.Type: GrantFiled: January 11, 2020Date of Patent: April 19, 2022Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Huawei Jiang, Huaifang Jiang
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Patent number: 11307136Abstract: The disclosed scanner for detecting a decay time of light emitted by a luminescent material has a control unit operable to adapt the drive current, or the value of the drive voltage, powering its light source to accordingly adapt the intensity of excitation light delivered to the luminescent material so that its high sensitivity light sensor can reliably measure the luminescence light emitted in response to the excitation light, and thus accurately determine a corresponding decay time value.Type: GrantFiled: December 13, 2018Date of Patent: April 19, 2022Assignee: SICPA HOLDING SAInventors: Frédéric Pierson, Joël Bonny, Samuel Brügger, Daniel Zahnd
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Patent number: 11302163Abstract: A system, device and method facilitate accurate detection of gunshot events through spectrum analysis of impulse signals and/or evaluating impulse signal exponential decay amplitude and time values. In various embodiments, the device and system employ an acoustic sensor, one or more high-pass and low-pass filters, a threshold detector, a differentiator, a decay waveform shape generator, one or more comparators and one or more timers to facilitate detection of gunshot events and/or components of gunshot events.Type: GrantFiled: September 10, 2021Date of Patent: April 12, 2022Assignee: Halo Smart Solutions, Inc.Inventors: David Antar, Paul Galburt, Frank L. Jacovino, David Rayna
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Patent number: 11300695Abstract: A Time-Resolved PET imaging system for producing an event-by-event, real-time, high resolution, three-dimensional positron emission tomographic images without performing sinogram formation or image reconstruction. The third dimension is provided by measuring the ?T between the arrival times of gamma rays from a positron event being detected by two cooperating detectors. In order to determine the location of a positron event along the lines of response, the measurement includes a fast scintillator, constant fraction discriminator and the digital intervalometer. The arrival time of each photon in the annihilation process is recorded with respect to a clock frequency with picosecond resolution. This approach requires significantly fewer positron events, thus requiring fewer detectors, thereby resulting in an gamma event-by-gamma event, real-time TPET imaging system that is more efficient and more economical to produce than conventional PET systems.Type: GrantFiled: June 7, 2021Date of Patent: April 12, 2022Inventors: Ronald Nutt, Lynda J. Nutt
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Patent number: 11288847Abstract: Methods for simulating, and correcting for, doubly scattered annihilation gamma-ray photons in both time-of-flight (TOF) and non-TOF positron emission tomography scan data are disclosed.Type: GrantFiled: October 10, 2019Date of Patent: March 29, 2022Assignee: Siemens Medical Solutions USA, Inc.Inventors: Charles C. Watson, Jicun Hu, Chuanyu Zhou
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Patent number: 11280921Abstract: A time correction device for a PET system comprises a detector ring, a ring-shaped prosthesis, and detection, data acquisition, data coincidence, time shift calculation, data correction application modules. Center of the ring-shaped prosthesis overlaps with axial and radial center of the detector ring. The detection module is located in ring-shaped prosthesis. Center of the detection module is at the center of the ring-shaped prosthesis. The data acquisition module comprises data gathering and energy filtering modules connected to each other. The data gathering module comprises detectors and the detection module. The energy filtering module connects to the data gathering module receiving single-event time information. The data coincidence module is connects to the energy filtering module receiving the single-event time information. Time shift calculation module connects to the data coincidence module providing a shift value of the detectors.Type: GrantFiled: August 28, 2017Date of Patent: March 22, 2022Assignee: RAYCAN TECHNOLOGY CO., LTD (SU ZHOU)Inventors: Ming Niu, Tong Liu, Qingguo Xie
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Patent number: 11277905Abstract: A radiation imaging apparatus comprises a sensor unit including two sensor boards stacked together, a base supporting the sensor unit, an electrical component on an opposite side to the sensor unit relative to the base, and a heat insulation member including a portion located between the electrical component and the sensor unit. A heat conductivity of the heat insulation member is lower than a heat conductivity of the base.Type: GrantFiled: June 20, 2019Date of Patent: March 15, 2022Assignee: CANON KABUSHIKI KAISHAInventors: Kazumi Nagano, Keiichi Nomura, Shinichi Takeda, Tomoyuki Oike
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Patent number: 11249201Abstract: A scintillator material includes a matrix phase and scintillator parts dispersed in the matrix phase. The scintillator parts contain fine particles of single crystal. According to the above aspect, since the scintillator parts containing the fine particles of single crystal are dispersed in the matrix phase, it is possible to reduce an influence from an environment.Type: GrantFiled: October 5, 2018Date of Patent: February 15, 2022Assignee: KOITO MANUFACTURING CO., LTD.Inventor: Hisayoshi Daicho
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Patent number: 11234677Abstract: The invention concerns a detecting apparatus (12) comprising:—at least two sensors (24, 26, 28), with at least one sensor (24) being an ultrasound transducer adapted to produce ultrasound waves, and—a positioning device (16) defining several compartments (22), each compartment (22) being adapted to hold a sensor (24, 26, 28) and each compartment (22) being located at predetermined location, the positioning device (16) comprising a holder adapted to be fixed on the skull of a subject, the positioning device (16) being adapted to be maintained on the head of the subject using the holder.Type: GrantFiled: June 9, 2016Date of Patent: February 1, 2022Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie (Paris 6), Université Paris Diderot—Pris 7, Ecole Superieure de Physique et de Chimie Industrielles de la Ville de ParisInventors: Jean-Luc Gennisson, Mickaël Tanter, Thomas Deffieux, Mathieu Pernot
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Patent number: 11213264Abstract: A positron emission tomography (PET) assembly includes an annular housing and an annular scintillator disposed within the annular housing. The annular scintillator includes an annular, substantially continuous crystal scintillator tube configured to absorb ionizing radiation and to emit light energy. A plurality of photo detectors are annularly disposed around the annular scintillator within the annular housing and configured to detect the emitted light energy.Type: GrantFiled: November 23, 2016Date of Patent: January 4, 2022Assignee: University of Virginia Patent FoundationInventors: Stuart S. Berr, Stanislaw Majewski, JosE Maria Benlloch Baviera, Antonio Javier Gonzalez Martinez
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Patent number: 11185297Abstract: A detector module system for positron emission tomography including a plurality of gamma ray detector modules. Each pair of one detector module and one interconnection element includes mutually engaging locking means for releasably connecting the detector module to the interconnection element. Further each interconnection element includes locking means for releasably connecting at least two detector modules to said interconnection element. Further each of said gamma ray detector modules includes a sensor adapted to detect gamma radiation occurring from short-lived radionuclides radiating from a body and to generate a radiation output corresponding to the detected gamma radiation, and the detector module system comprises a processing circuitry adapted to receive said radiation output from each of the gamma ray detector modules and to generate a resulting radiation representation for the positron emission tomography event, based on the received radiation output.Type: GrantFiled: October 25, 2019Date of Patent: November 30, 2021Assignee: TERAPET LTD.Inventors: Christina Vallgren, Marcus Palm
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Patent number: 11166684Abstract: A variable PET apparatus allows structural changes of detector modules in transversal and longitudinal directions to correspond to various imaging purposes and a cross-sectional diameter of a subject while maintaining an arrangement of the detector modules to be close to a true circle. The variable PET apparatus includes: a gantry having an opening on a longitudinal axis; and detector modules supported on the gantry and arranged a predetermined distance apart from each other such that a detection ring is configured with a diameter in a circumferential direction, wherein the gantry is driven by a gantry drive member, and the detector modules are driven by a detector module drive member. According to the present invention, structural changes of the detector modules in the PET apparatus is possible to correspond to a cross-sectional diameter of a subject without additional devices, thereby improving the spatial resolution and sensitivity.Type: GrantFiled: October 31, 2017Date of Patent: November 9, 2021Assignees: Gachon University of Industry-Academic Cooperation Foundation, GIL Medical CenterInventors: Seong-Ho Seo, Sang-Yoon Lee, Jun-Young Chung, Ji-Hye Lee
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Patent number: 11154262Abstract: Detector heads in a gantry of a medical imaging apparatus are pivotally-coupled to mounting rails oriented axially about the gantry's axial centerline. Radial alignment blocks facilitate alignment and fixation of detector faces circumferentially transverse and normal to a radius projecting from the gantry's axial centerline. A column of detector heads on a common rail are separated by axial stop blocks, for precise axial separation. Abutting detector heads on a common mounting rail are slaved to another previously transverse-aligned detector through a common, shared radial alignment block. Plural, stacked gantry backplanes are fabricated simultaneously, assuring common circumferential and radial co-registration of plural mounting rails relative to the axial centerline of the gantry. Adjustable orientation of the detector heads compensates for tolerance stack up during final assembly of the gantry, so that the detector heads are mutually aligned in a uniform grid of axial columns and circumferential rows.Type: GrantFiled: June 25, 2020Date of Patent: October 26, 2021Assignee: Siemens Medical Solutions USA, Inc.Inventors: James L. Corbeil, Nicholas Gullette, Jeffrey Bostrom
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Patent number: 11150364Abstract: A crystal array, a detector, a medical detection device and a method for manufacturing a crystal array are provided. The crystal array includes a plurality of crystals arranged in an array, each of the crystals having a light incident surface, a light exit surface, and a connection surface connecting the light incident surface to the light exit surface, where the connection surface of at least one of two adjacent crystals includes a rough surface and a smooth surface connected to the rough surface, and the rough surface and the smooth surface are arranged along a length direction of the crystal.Type: GrantFiled: April 27, 2020Date of Patent: October 19, 2021Assignee: Shanghai Neusoft Medical Technology Co., Ltd.Inventors: Xinying Li, Xi Wang, Jian Zhao, Baowei Xu, Guodong Liang
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Patent number: 11145778Abstract: An optical system may include a substrate and a plurality of silicon photomultipliers (SiPMs) monolithically integrated with the substrate. Each SiPM may include a plurality of single photon avalanche diodes (SPADs). The optical system also includes an aperture array having a plurality of apertures. The plurality of SiPMs and the aperture array are aligned so as to define a plurality of receiver channels. Each receiver channel includes a respective SiPM of the plurality of SiPMs optically coupled to a respective aperture of the plurality of apertures.Type: GrantFiled: September 20, 2019Date of Patent: October 12, 2021Assignee: Waymo LLCInventors: Caner Onal, Pierre-Yves Droz, Nirav Dharia
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Patent number: 11096634Abstract: Systems and methods include acquisition of data representing true coincidences and scatter coincidences detected by the plurality of detectors, allocation of the data into respective ones of a plurality of energy ranges, determination of a baseline response associated with each of a subset of the plurality of energy ranges, generation of data representing expected true coincidences associated with each of the subset of the plurality of energy ranges based on the data allocated to each of the subset of the plurality of energy ranges and the baseline response associated with each of the subset of the plurality of energy ranges, determination of a raw scatter estimate based on the data representing expected true coincidences associated with each of the subset of the plurality of energy ranges and the data allocated to each of the subset of the plurality of energy ranges, and reconstruction of an image based on the raw scatter estimate and the data representing true coincidences and scatter coincidences.Type: GrantFiled: June 16, 2020Date of Patent: August 24, 2021Assignee: Siemens Medical Solutions USA, Inc.Inventor: Harshali Bal
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Patent number: 11096633Abstract: A positron emission tomography scanner includes a plurality of gamma-ray detector rings that form a bore through which an imaging subject is translated, each of the plurality of gamma-ray detector rings being in a first axial position, and processing circuitry configured to receive attenuation data associated with a plurality of transaxial slices of the imaging subject, determine a second axial position of each of the plurality of gamma-ray detector rings based on the received attenuation data, and adjust a position of each of the plurality of gamma-ray detector rings from the first axial position to the second axial position. The processing circuitry may further be configured to calculate an attenuation metric based on the received attenuation data, and determine the second axial position such that the attenuation metric calculated for each pair of adjacent gamma-ray detector rings is equal.Type: GrantFiled: May 27, 2020Date of Patent: August 24, 2021Assignee: CANON MEDICAL SYSTEMS CORPORATIONInventors: Wenyuan Qi, Yi Qiang, Evren Asma, Jeffrey Kolthammer
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Patent number: 11058391Abstract: A method for determining a correction profile of an imaging device may include obtaining first data relating to the imaging device; comparing the first data and a first condition; obtaining, based on the comparison, a first correction profile relating to the imaging device; and calibrating, based on the first correction profile, the imaging device.Type: GrantFiled: December 30, 2018Date of Patent: July 13, 2021Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yixing Sun, Shitao Liu
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Patent number: 11058371Abstract: A method of PET image reconstruction is provided that includes obtaining intra-patient tissue activity distribution and photon attenuation map data using a PET/MRI scanner, and implementing a Maximum Likelihood Expectation Maximization (MLEM) method in conjunction with a specific set of latent random variables, using an appropriately programmed computer and graphics processing unit, wherein the set of latent random variables comprises the numbers of photon pairs emitted from an electron-positron annihilation inside a voxel that arrive into two given voxels along a Line of Response (LOR), where the set of latent random variables results in a separable joint emission activity and a photon attenuation distribution likelihood function.Type: GrantFiled: October 30, 2014Date of Patent: July 13, 2021Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Alexander Mihlin, Craig S. Levin
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Patent number: 11061151Abstract: A positron emission tomography (PET) detector array includes an enclosing radiation detector array (10) comprising radiation detector elements (14, 16) effective for detecting 511 keV radiation emanating from inside the radiation detector array. The radiation detector pixels of the cylindrical radiation detector array include both higher speed radiation detector elements (14) and lower speed radiation detector elements (16). The lower speed radiation detector pixels have a temporal resolution that is coarser than a temporal resolution of the higher speed radiation detector pixels.Type: GrantFiled: December 4, 2017Date of Patent: July 13, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Chuanyong Bai, Andriy Andreyev, Bin Zhang, Zhiqiang Hu
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Patent number: 11051773Abstract: A system is provided that includes at least one detector and a processing unit. The at least one detector is configured to acquire imaging information. The processing unit is operably coupled to the at least one detector, and is configured to acquire the imaging information from the at least one detector. The processing unit is configured to acquire patient scanning information for an imaging operation, determine a target activity based on the patient scanning information, determine a target time for performing the imaging operation corresponding to the target activity, perform the imaging operation at the target time to acquire targeted imaging information; and reconstruct an image using the targeted imaging information.Type: GrantFiled: December 4, 2017Date of Patent: July 6, 2021Assignee: GENERAL ELECTRIC COMPANYInventors: Nitin Jain, Charles Stearns, Savitha V S
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Patent number: 11041819Abstract: A visual test system for a secondary generation or decomposition of a hydrate includes a hydrate conveying device, a computerized tomography (CT) imaging device, a temperature control device, a pressure control device and a flow control device. The hydrate conveying device includes an annular pipeline structure composed of a plurality of straight pipeline sections and a plurality of curved pipeline sections. The straight pipeline section is able to rotate around an axis thereof under the drive of a pipeline driving device. The CT imaging device is used to perform a three-dimensional (3D) detection inside the pipeline, and includes a turntable, a ray source and a detector. The ray source is able to rotate under the drive of the turntable driving device. The temperature control device, the pressure control device and the flow control device are used to control a gas-liquid mixture's temperature, pressure and flow rate, respectively.Type: GrantFiled: March 2, 2021Date of Patent: June 22, 2021Assignee: INSTITUTE OF GEOLOGY AND GEOPHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Xiao Li, Bo Zheng, Shouding Li, Jianming He, Zhaobin Zhang, Tianqiao Mao, Guanfang Li, Yanfang Wu
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Patent number: 11031210Abstract: A scintillator assembly including an entrance surface for receiving charged particles into the scintillator assembly, the charged particles including first charged particles at a first energy level and second charged particles at a second energy level. A first scintillator structure configured for receiving the first charged particles and generating a corresponding first signal formed of first photons with a first wavelength of ?1, a second scintillator structure configured for receiving the second charged particles and generating a corresponding second signal of second photons with a second wavelength of ?2, and an emitting surface for egress of a combined signal from the scintillator assembly, the combined signal including the first and second photons, and at least one beam splitter for receiving the combined signal and separating the combined signal to first and second photons.Type: GrantFiled: March 6, 2020Date of Patent: June 8, 2021Assignee: EL-MUL TECHNOLOGIES LTD.Inventors: Dmitry Shur, Eli Cheifetz, Armin Schon
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Patent number: 11017540Abstract: In some aspects, the techniques described herein relate to systems, methods, and computer readable media for data pre-processing for stereo-temporal image sequences to improve three-dimensional data reconstruction. In some aspects, the techniques described herein relate to systems, methods, and computer readable media for improved correspondence refinement for image areas affected by oversaturation. In some aspects, the techniques described herein relate to systems, methods, and computer readable media configured to fill missing correspondences to improve three-dimensional (3-D) reconstruction. The techniques include identifying image points without correspondences, using existing correspondences and/or other information to generate approximated correspondences, and cross-checking the approximated correspondences to determine whether the approximated correspondences should be used for the image processing.Type: GrantFiled: April 23, 2019Date of Patent: May 25, 2021Assignee: Cognex CorporationInventor: Marcus Große