Beta Branched Fatty Acid Patents (Class 260/DIG44)
  • Asymmetric hydrogenation catalyzed by rhodium complexes of chiral tertiary phosphines
    Patent number: 4115417
    Abstract: A method for the homogeneous catalytic enantioselective hydrogenation of alkyl and alkenyl substituted acrylic acids wherein these acids are selectively hydrogenated at the double bond alpha, beta to the acid function, said hydrogenations are catalyzed by rhodium complexes of chiral tertiary phosphines. This method provides a route to chiral dihydrogeranic acid and other intermediates useful in the synthesis of chiral vitamin E, citronellal, and menthol. Novel chiral tertiary phosphines are also disclosed.
    Type: Grant
    Filed: August 10, 1977
    Date of Patent: September 19, 1978
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Donald Herman Valentine, Jr.
  • Asymmetric synthesis of optically active compounds
    Patent number: 4000169
    Abstract: Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
    Type: Grant
    Filed: January 27, 1975
    Date of Patent: December 28, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ka-Kong Chan, Gabriel Saucy
  • 2,4-Dodecadienoic acid esters and use for insecticides
    Patent number: 3983247
    Abstract: The present invention relates to polyene compounds, a process for their preparation, pesticidal compositions containing same, and a method of providing a locus free from pests using said pesticides, alone or in composition.
    Type: Grant
    Filed: March 18, 1975
    Date of Patent: September 28, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Madhukar Subraya Chodnekar, Ulrich Schwieter, Peter Loeliger, Albert Pfiffner, Milos Suchy, Rene Zurfluh
  • Process for the preparation of tridecadien derivatives
    Patent number: 3957729
    Abstract: A process for preparing 2-cis,6-trans-10,11-epoxy-6-ethyl-3,11-dimethyl-2,6-tridecadien derivatives and mixtures of said 2-cis,6-trans-tridecadienn derivatives with its corresponding 2-trans,6-trans-geometric isomers which are useful in killing and preventing proliferation of insects, by upsetting their hormone balance including intermediates in this process.
    Type: Grant
    Filed: December 5, 1968
    Date of Patent: May 18, 1976
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Frank Ratcliffe Atherton, Albert Pfiffner
  • Organic compounds
    Patent number: 3952035
    Abstract: The invention concerns novel unsaturated fatty acids useful as inhibitors of prostoglandin synthetase.
    Type: Grant
    Filed: April 19, 1974
    Date of Patent: April 20, 1976
    Assignee: Sandoz Ltd., (Sandoz AG)
    Inventors: Eugene Ervin Galantay, Heribert Wagner