Abstract: The invention relates to a contact glass for ophthalmic surgery. Said glass comprises a lens body that is held in a frame and a front lens surface that is designed to be placed against the eye. According to the invention, the front lens surface is concave and follows a surface curvature (K) and an annular gap is formed at the edge of the front lens surface between the lens body and the frame, said gap being used to apply a negative pressure in order to fix the contact glass to the eye. The frame is designed to follow the contour of an imaginary continuation of the surface curvature (K), or at least does not project beyond the latter.

Abstract: The present disclosure provides electroretinography devices configured to detect biopotential signals from an eye of a subject. In some embodiments, the device is configured to prevent the subject's eyelids from closing over the device when placed in contact with the anterior surface of the subject's eye. In some embodiments, the device has a Young's modulus of no more than about 50 MPa. In some embodiments, the device includes a diffusing or refracting element configured to scatter, focus or diverge incident light. In other embodiments, the device includes a void through which incident light can enter the subject's eye without passing through any portion of the device.

Abstract: Single piece ophthalmic inspection devices are provided having a continuous 3-dimensional molded surface preferably made out of plastic. The devices are relatively easier and cheaper to manufacture than existing inspection lenses. The smooth continuous edges are advantages to prevent damage to tissue as well to stop foreign objects accumulating in e.g. the clear regions of the lens. Ergonomic features built into the ophthalmic inspection device provide for superior control of the device on the patient's eye. In addition, textured knurled or grooved surfaces provide desired finger grip and control of the device.

Abstract: This application describes a kit of contact lenses comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order aberration of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.

Abstract: A contact lens assembly has a central lens and a circumscribing flange, the lens having an eye contact surface shaped generally to a radius of curvature of a cornea of an eye. The flange comprises a sterile sponge-like liquid absorbent flexible material having a central aperture for fitting snugly about an outer circumference of the lens and extending radially outward therefrom. The flange may include an inner attachment ring for attachment to the outer circumference of the central contact lens.

Abstract: A contact lens is provided. It is a rigid gas permeable, corneal-scleral progressive, multifocal, vision lens that covers the cornea and a portion of the sclera of an eye. It is particularly beneficial for use on patients who have undergone refractive surgery and/or on patients experiencing presbyopia. The lens is designed to have dual touch contact with an eye. One contact point is the central portion of the cornea and the other contact point is a portion of the sclera.

Abstract: This disclosure relates generally to methods and devices for use in viewing and positioning an eye with a gonio lens system, such as during ocular exams and ocular surgeries. Some embodiments of the gonio lens system can include a gonio lens for viewing one or more tissues and structures of the eye. In addition, the gonio lens system can include one or more positioning features for controlling movement positioning of the eye.

Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

Abstract: This disclosure relates to systems and/or methods for detection of eye blinking by interrogating a passive surface acoustic wave based contact lens using an interrogation signal and interpreting reflections of the interrogation signal from the passive surface acoustic wave based contact lens.

Abstract: Single piece ophthalmic inspection devices are provided having a continuous 3-dimensional molded surface preferably made out of plastic. The devices are relatively easier and cheaper to manufacture than existing inspection lenses. The smooth continuous edges are advantages to prevent damage to tissue as well to stop foreign objects accumulating in e.g. the clear regions of the lens. Ergonomic features are built into the ophthalmic inspection device provide for superior control of the device on the patient's eye. In addition, textured knurled or grooved surface provide desired finger grip and control of the device.

Abstract: A method and system perform physiological monitoring. The system includes a first light source and a plurality of optical waveguide couplers, each of the plurality of optical waveguide couplers being arranged at a different predetermined spatial location on an ocular insert to be placed on an eye. The system also includes a plurality of optical waveguides. Each optical waveguide carries light from a second light source to a respective one of the plurality of optical waveguide couplers and carries a received signal from the respective one of the plurality of optical waveguide couplers. A processor receives the received signal from each of the plurality of optical waveguides and monitors a parameter based on the received signal.

Abstract: The invention provides a method of monitoring the pupil of a subject, wherein a sensor for observing the pupil is arranged between the cornea and the eyelid covering the cornea, the sensor is powered through the eyelid, and the pupil-observation signals delivered by the sensor are collected through the eyelid.

Abstract: A method and system perform physiological monitoring. The system includes a first light source and a plurality of optical waveguide couplers, each of the plurality of optical waveguide couplers being arranged at a different predetermined spatial location on an ocular insert to be placed on an eye. The system also includes a plurality of optical waveguides. Each optical waveguide carries light from a second light source to a respective one of the plurality of optical waveguide couplers and carries a received signal from the respective one of the plurality of optical waveguide couplers. A processor receives the received signal from each of the plurality of optical waveguides and monitors a parameter based on the received signal.

Abstract: A system and method for automated determination of position and movement of a contact lens with respect to a subject wearer's eye based upon a complimentary pair of images, acquired in rapid succession, in which one image of the pair is acquired using light that allows viewing of the pupil and/or limbus through the lens and the other image is acquired using light that is absorbed by the lens to generate an opaque image with a defined edge relative to the surrounding sclera. The images of the pair are acquired in close enough temporal proximity to ensure that eye movement in the interval therebetween is insignificant and both images are in the same approximate reference frame. Thus, the location of the pupil and limbus in one image can be accurately compared with the location of the contact lens edge in the other image.

Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.

Abstract: Methods and systems for changing a property of an eye. A property of the eye can be changed using an aspheric profile for increasing a depth of focus. Aspheric profile generation can include calculating a shape for increasing the focal depth to be rotationally symmetrical.

Abstract: The invention concerns a scanning device for focusing a beam of rays in defined regions of a defined volume, comprising an input optics wherein the beam of rays penetrates first, having at least one first optical element; a focusing optics for focusing the beam of rays exiting from the input optics; and a deflecting device arranged between the first optical element and the focusing optics, for deflecting the beam of rays after it has passed through the first optical element, based on a position of the focus to be adjusted in lateral direction. In order to adjust the position of the focus of the beam of rays in the direction of the beam of rays, and optical element of the input optics can be displaced relative to the deflecting device.

Abstract: A disposable ophthalmic or medical apparatus has a portion with a color changeable dye disposed thereon. The dye changes color after being exposed to oxygen for a controlled and predetermined period of time indicating that the apparatus should no longer be used.

Abstract: An ophthalmoscopic surgical contact lens for placement on an eye of a patient is disclosed. The surgical contact lens includes an optic surrounded by a rim and at least one flange. The optic includes an aspheric anterior surface and a posterior surface having a shape substantially corresponding to the shape of a human cornea. The rim, comprising an edge surrounding the optic, provides the user with a gripping surface conducive to manual positioning and repositioning of the lens against a human eye. The flange may include a plurality of tabs extending from a periphery of the flange, wherein each tab is shaped and configured to conform to the curvature of a human sclera. Various embodiments of the contact lenses disclosed herein facilitate the visualization of structures within the interior of an eye, such as may be necessary during vitreoretinal surgical procedures.

Abstract: The invention pertains to methods, components, and operations of multi-focal intraocular lens systems, including range finding for driving same and for discriminating between multiple objects and varying brightness conditions. The invention also pertains to intraocular photosensors and range-finding methods to be used with intra-ocular lens systems, and components, that provide multi-focal IOL capabilities in dynamic visual environments.

Abstract: Methods of eye gaze tracking are provided using magnetized contact lenses tracked by magnetic sensors and/or reflecting contact lenses tracked by video-based sensors. Tracking information of contact lenses from magnetic sensors and video-based sensors may be used to improve eye tracking and/or combined with other sensor data to improve accuracy. Furthermore, reflective contact lenses improve blink detection while eye gaze tracking is otherwise unimpeded by magnetized contact lenses. Additionally, contact lenses may be adapted for viewing 3D information.

Abstract: System for monitoring at least one biomechanical ophthalmic parameter, the system comprising a measuring device (1) adapted to be placed on or implanted into an eye of a patient for measuring said at least one biomechanical ophthalmic parameter of said eye, a recording device (6) for obtaining from said measuring device (1) measurement data representative of the instant value of said at least one biomechanical ophthalmic parameter of said eye, wherein said recording device is adapted to obtain said measurement data at a predetermined frequency equal to or greater than twice the variation frequency of said at least one biomechanical ophthalmic parameter.

Abstract: A wavefront sensor is integrated with a surgical microscope for allowing a doctor to make repeated wavefront measurements of a patient's eye while the patient remains on an operating table in the surgical position. The device includes a wavefront sensor optically aligned with a surgical microscope such that their fields of view at least partially overlap. The inclusion of lightweight, compact diffractive optical components in the wavefront sensor allows the integrated device to be supported on a balancing mechanism above a patient's head during a surgical procedure. As a result, the need to reposition the device and/or the patient between measuring optical properties of the eye and performing surgical procedures on the eye is eliminated. Many surgical procedures may be improved or enhanced using the integrated device, including but not limited to cataract surgery, Conductive Keratoplasty, Lasik surgery, and corneal corrective surgery.

Abstract: A contact lens having an integrated glucose sensor is provided. The contact lens includes an electrochemical sensor configured to measure the level of glucose in the tear fluid of the eye of the user wearing the contact lens. The electrochemical sensor is powered by radiation off-lens, through an RF antenna or a photovoltaic device mounted on the periphery of the contact lens. The power provided to the contact lens also enables transmission of data from the electrochemical sensor, for example by backscatter communications or optically by an LED mounted to the lens.

Abstract: A device (20) and methods for concurrently taking multiple partially overlapping still or video images (60) of the iridocorneal angle (12) of an eye (1). Device (20) typically comprises a single chassis (100) with an outer surface (101) that approximately matches the curvature of the ocular surface (4). Multiple discrete optical imaging systems (200) are aimed through the cornea (3) and the anterior chamber (17), producing non-coplanar optical paths (21) directed towards corresponding partially overlapping zones (11) of the iridocorneal angle (12). Each system (200) may comprise one or more optical lenses (210, 211), with either fixed or variable position, and a corresponding digital sensor (220) or portion of a larger common shared digital sensor (221).

Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

Abstract: This application describes a kit of contact lenses comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order aberration of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.

Abstract: A phase diversity wavefront sensor includes an optical system including at least one optical element for receiving a light beam; a diffractive optical element having a diffractive pattern defining a filter function, the diffractive optical element being arranged to produce, in conjunction with the optical system, images from the light beam associated with at least two diffraction orders; and a detector for detecting the images and outputting image data corresponding to the detected images. In one embodiment, the optical system, diffractive optical element, and detector are arranged to provide telecentric, pupil plane images of the light beam. A processor receives the image data from the detector, and executes a Gerchberg-Saxton phase retrieval algorithm to measure the wavefront of the light beam.

Abstract: A suspended goniolens system is provided. The suspended goniolens system includes a balance arm with a goniolens disposed at one end and a counterbalance disposed towards an opposing end. The system can position the goniolens in a desired position near a patient's eye and can maintain the desired position without the need to be held in place by a clinician. The suspended goniolens system allows for the clinician to use both hands during treatment of the patient. The goniolens system can be attached to an optical microscope or an adapter engaged with the optical microscope. Methods are also provided for using the goniolens system.

Abstract: The invention proposes a manual measuring appliance (112) and an analytical measuring system (110) which can be used to measure at least one analyte in an eye fluid of an eye (114). The handheld measuring appliance (112) comprises a measuring system (120) and a positioning system (122). The measuring system (120) can measure at least one property of the at least one analyte and/or at least one analyte-dependent change of property of at least one ocular sensor (116) in the eye fluid, and this can be used to infer a concentration of the analyte in the eye fluid. The positioning system (122) is set up to measure a spatial positioning, wherein the spatial positioning comprises a distance between at least one measurement location in the eye (114) and the handheld measuring appliance (112) and also furthermore at least one further positioning co-ordinate.

Abstract: The present invention provides a kit of contact lenses, comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order aberration of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.

Abstract: An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

Abstract: This disclosure relates generally to methods and devices for use in viewing and positioning an eye with a gonio lens system, such as during ocular exams and ocular surgeries. Some embodiments of the gonio lens system can include a gonio lens for viewing one or more tissues and structures of the eye. In addition, the gonio lens system can include one or more positioning features for controlling movement positioning of the eye.

Abstract: Disclosed is a method of determining an appropriately shaped soft contact lens for a subject with an irregular cornea, the method comprising the steps of: inferring or deducing the profile of the cornea over at least a portion thereof: selecting a first choice fitting lens, the selection being based on the profile of the cornea obtained in the preceding step; assessing the fit of the contact lens to the cornea, by investigating each of the following parameters; (i) translational movement of the lens on eye; (ii) rotation of the lens on eye; (iii) centration of the lens on eye; (iv) the perceived comfort of the lens for the subject; (v) the visual acuity of the subject when wearing the lens; and adjusting the choice of fitting lens, if required, according to the assessment and reiterating until a desired fit of lens to the cornea has been obtained.

Abstract: A surgical microscope assembly includes a microscope main objective and microscope imaging optics. The microscope main objective and microscope imaging optics define a viewing beam path that passes from a sample through the microscope main objective and the microscope imaging optics. The assembly includes an optical coherence tomography (OCT) unit having an illumination beam and a collection beam and a beamsplitter between the microscope main objective and the microscope imaging optics. The beamsplitter is configured to direct a portion of light from the microscope main objective to the microscope imaging optics and to direct another portion of light from the microscope main objective to the OCT unit collection beam. The beamsplitter is further configured to direct an illumination beam from the OCT unit to the microscope main objective and to the sample. A beam forming unit is between the OCT unit and the beamsplitter.

Abstract: Disclosed is a method of determining an appropriately shaped soft contact lens for a subject with an irregular cornea, the method comprising the steps of: inferring or deducing the profile of the cornea over at least a portion thereof: selecting a first choice fitting lens, the selection being based on the profile of the cornea obtained in the preceding step; assessing the fit of the contact lens to the cornea, by investigating each of the following parameters; (i) translational movement of the lens on eye; (ii) rotation of the lens on eye; (iii) centration of the lens on eye; (iv) the perceived comfort of the lens for the subject; (v) the visual acuity of the subject when wearing the lens; and adjusting the choice of fitting lens, if required, according to the assessment and reiterating until a desired fit of lens to the cornea has been obtained.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: An ophthalmic is injection molded and/or, compression molded to provide a single use lens. The ophthalmic lens has a larger clear aperture than known lenses of the same type to improve the optical quality of the lens.

Abstract: An ophthalmic apparatus including a supporting device for a patient and an eye treatment device. The apparatus includes a contact element for spatially fixing an eye of the patient with respect to the treatment device, and a positioning device for shifting the supporting device and a contact element relative to each other in order to position the eye, before it is fixed using the contact element, at a predetermined nominal position relative to the contact elements. The ophthalmic apparatus includes a detection device, which records an image of the eye of the patient present on the supporting device and, on the basis of said recorded image, determines an indication concerning a relative shift of the supporting device with respect to the contact element, which shift is required to move the eye to the nominal position by means of the positioning device.

Abstract: Various embodiments relate to ophthalmoscopic devices, systems and methods for viewing the anterior chamber, trabecular meshwork, iris root, scleral spur, and/or related nearby structures in the eye. In some embodiments, devices, systems and/or methods may employ a plurality of gonioscopic optical elements that form a virtual image that can be imaged by a microscope directly in front of a patient (e.g., without tilting the patient's head). Various embodiments described herein may be useful for ophthalmologic diagnoses, treatments, monitoring and/or surgical procedures. Some embodiments include a gonioscopic attachment configured to attach to a conventional gonioscope and redirect light emitted by the gonioscope. Various embodiments described herein can be incorporated into disposable, single-use gonioscopes. Some embodiments include a gonioscopic optical element that is movable with respect to another gonioscopic optical element.

Abstract: Single piece ophthalmic inspection devices are provided having a continuous 3-dimensional molded surface preferably made out of plastic. The devices are relatively easier and cheaper to manufacture than existing inspection lenses. The smooth continuous edges are advantages to prevent damage to tissue as well to stop foreign objects accumulating in e.g. the clear regions of the lens. Ergonomic features are built into the ophthalmic inspection device provide for superior control of the device on the patient's eye. In addition, textured knurled or grooved surface provide desired finger grip and control of the device.

Abstract: The invention relates to a method of determining and selecting a contact lens with an opthalmological device for examining the eyes, the opthalmological device comprising a keratometer and an autorefractometer as well as a data processor, whereby a refractive power of an eye and a topography of a cornea are determined, whereby refraction data describing a refraction of an eye to be examined are obtained, whereby topographic data describing the topography of the cornea of the eye are obtained, and whereby, by using the obtained refraction and topography data, contact lens data are calculated and a contact lens is selected from a database of the opthalmological device. In accordance with an apparatus embodiment of the invention, an opthalmological device for carrying out the method is also described.

Abstract: Methods, devices, and systems establish an optical surface shape that mitigates or treats a vision condition in a patient. An optical surface shape for a particular patient can be determined using a set of patient parameters for the specific patient by using a compound modulation transfer function (CMTF). The compound modulation transfer function can include a combination of modulation transfer functions (MTF's) at a plurality of distinct frequencies.

Abstract: A lens holding ring 50 is held by a string-like body 40a stretched along a surface of an eyeball 1 by being supported by a plurality of cannulas 21, 22 inserted to a sclera 2, and is fixed to the surface of the eyeball 1 by a tensile stress of the string-like body 40a, and in this state, holds a surgery lens 30 on the eyeball. The lens holding ring 50 comprises a lens holder 51 including an opening 52 into which a lens is inserted, and engagement parts 57 provided at positions opposed to each other across the opening 52. Each engagement part has an engagement structure of engaging with the string-like body 40a for fixing the lens holder to the surface of the eyeball so as to interpose the lens holder therein, and has a folded part 58 on the tip of the engagement part for preventing coming-off of the string-like body.

Abstract: An ophthalmic is injection molded and/or, compression molded to provide a single use lens. The ophthalmic lens has a larger clear aperture than known lenses of the same type to improve the optical quality of the lens.

Abstract: An ophthalmoscopic surgical contact lens for placement on an eye of a patient is disclosed. The surgical contact lens includes an optic surrounded by a rim and at least one flange. The optic includes an aspheric anterior surface and a posterior surface having a shape substantially corresponding to the shape of a human cornea. The rim, comprising an edge surrounding the optic, provides the user with a gripping surface conducive to manual positioning and repositioning of the lens against a human eye. The flange may include a plurality of tabs extending from a periphery of the flange, wherein each tab is shaped and configured to conform to the curvature of a human sclera. Various embodiments of the contact lenses disclosed herein facilitate the visualization of structures within the interior of an eye, such as may be necessary during vitreoretinal surgical procedures.

Abstract: The present invention provides a kit of contact lenses, comprising two or more contact lenses having a known higher order aberration for each given lens power. By way of example, the higher order aberration may comprise a spherical aberration, a coma aberration, or a trefoil aberration. A practitioner selects a lens from the kit and applies the lens to a patient's eye and measures a residual higher order aberration of the lens-eye system. In cases where the residual higher order aberration exceeds a predetermined magnitude, the practitioner selects a second lens from the kit, applies the second lens to the patient's eye and measures the residual higher order aberration of the lens-eye system.

Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.

Abstract: This invention discloses an apparatus that is attached to the objective lens of a microscope to split its field of view into at least two. In one embodiment, a mirrored gonio lens is snapped to the objective of an ophthalmic surgical microscope to provide a view of the eye's anterior surface and a view of the eye's anterior chamber.

Abstract: Methods for diagnosis and treatment are provided for a patient having processing difficulties, integration problems, imbalances or abnormal postures. In one embodiment, a patient is identified having retinal signal problems creating at least one negative medical condition. Then, at least a portion of the patient's lacrimal drainage system is blocked or altered. Further, as a result of the diagnosis and treatment, the patient achieves improved retinal signal processing and at least one of the patient's negative medical conditions is improved. Other embodiments include using in combination the Z-Bell Test and/or light blocking or altering devices for diagnosis and treatment.