By Inspection With Agitation Or Rotation Patents (Class 356/426)
  • Patent number: 10661276
    Abstract: Devices and methods for handling liquids are provided. The devices and methods make use of centrifugal forces to drive liquid flow and facilitate one or more of the mixing, metering and sequencing of liquids, for example on a microfluidic device.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: May 26, 2020
    Assignee: Biosurfit, S.A.
    Inventors: Tania Moura Pires De Andrade Tenreiro, Luis Miguel Dias Martins, Fábio Miguel Rolo Pereira, Nuno Alexandre Esteves Reis
  • Patent number: 10540567
    Abstract: Disclosed are a bin-picking system and a bin-picking method. A bin-picking system includes a transformable bin-picking box; a supporting unit configured to support the bottom part of the bin-picking box and be movable upward and downward; and a control unit configured to change an alignment of at least one bin-picking candidate object by transforming the bin-picking box by controlling a movement of the supporting unit if no bin-picking target object is detected from the at least one bin-picking candidate object existing inside bin-picking box and placed on the supporting unit to facilitate detection of a bin-picking target object and bin-picking.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: January 21, 2020
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Kye-Kyung Kim, Sang-Seung Kang, Jae-Yeon Lee, Jae-Hong Kim, Joong-Bae Kim, Sung-Woong Shin
  • Patent number: 9965835
    Abstract: A method and system are disclosed. The method may include determining a histogram of intensity values for pixels in image sensor data in which the histogram is bimodal. The method may include determining a breakpoint between the two modes. The histogram may include a first distribution of intensity values below the breakpoint and a second distribution of intensity values above the breakpoint. The method may include generating output intensity values. Generating output intensity values may include compressing the first distribution of intensity values of the pixels with intensity values below the breakpoint, stretching the second distribution of intensity values of the pixels with intensity values above the breakpoint, and generating an output image based on the output intensity values.
    Type: Grant
    Filed: November 28, 2014
    Date of Patent: May 8, 2018
    Assignee: Axis AB
    Inventors: Fredrik Svensson, Per Kannermark, Andreas Nilsson
  • Patent number: 8953870
    Abstract: A surface inspection device includes an image generator for generating a digital image achieved by imaging an inner surface of a bore which is subjected to a boring work, a line extraction processor for extracting a line along a horizontal direction set to a line extraction direction from the digital image, for determining the state of the inner surface of the bore based on the line extracted by the line extraction processor. The line extraction processor extracts lines along the line detection direction from respective digital images before and after rotation which are achieved by rotating the digital image once or over plural times every predetermined angle while the line extraction direction is fixed, and the estimating unit determines the state of the inner surface of the bore based on the lines extracted from the respective digital images before and after the rotation.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: February 10, 2015
    Assignee: Honda Motor Co., Ltd.
    Inventors: Satoshi Oikawa, Satoshi Nojo
  • Patent number: 8730465
    Abstract: A defect inspecting apparatus inspects defects of a sample having a pattern formed on the surface. The defect inspecting apparatus is provided with a stage which has a sample placed thereon and linearly moves and turns; a light source; an illuminating optical system, which selects a discretionary wavelength region from the light source and epi-illuminates the sample surface through a polarizer and an objective lens; a detecting optical system, which obtains a pupil image, by passing through reflection light applied by the illuminating optical system from the surface of the sample through the objective lens and an analyzer which satisfies the cross-nichols conditions with the polarizer; and a detecting section which detects defects of the sample by comparing the obtained pupil image with a previously stored pupil image. Conformity of the pattern on a substrate to be inspected can be judged in a short time.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: May 20, 2014
    Assignee: Nikon Corporation
    Inventors: Kazumasa Endo, Daisaku Mochida, Toru Yoshikawa, Hiromasa Shibata, Akitoshi Kawai
  • Patent number: 8701512
    Abstract: Disclosed herein is a cell for testing microbeads, used for testing microbeads each formed in a cylindrical shape having an upper surface and a lower surface opposite to and substantially parallel to each other and a side surface continuous with the upper and lower surfaces, at least one of the upper surface and the lower surface being provided with an identification pattern, the cell including: a support substrate; and a cover disposed opposite to the support substrate, wherein a space between the support substrate and the cover forms a containing space in which to dispose the microbeads, and the distance between the support substrate and the cover is greater than the thickness of the microbeads and smaller than twice the thickness of the microbeads.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: April 22, 2014
    Assignee: Sony Corporation
    Inventors: Naohisa Sakamoto, Noriyuki Kishii, Kazumine Ito
  • Patent number: 8599370
    Abstract: A defect inspecting apparatus inspects defects of a sample having a pattern formed on the surface. The defect inspecting apparatus is provided with a stage which has a sample placed thereon and linearly moves and turns; a light source; an illuminating optical system, which selects a discretionary wavelength region from the light source and epi-illuminates the sample surface through a polarizer and an objective lens; a detecting optical system, which obtains a pupil image, by passing through reflection light applied by the illuminating optical system from the surface of the sample through the objective lens and an analyzer which satisfies the cross-nichols conditions with the polarizer; and a detecting section which detects defects of the sample by comparing the obtained pupil image with a previously stored pupil image. Conformity of the pattern on a substrate to be inspected can be judged in a short time.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: December 3, 2013
    Assignee: Nikon Corporation
    Inventors: Kazumasa Endo, Daisaku Mochida, Toru Yoshikawa, Hiromasa Shibata, Akitoshi Kawai
  • Patent number: 8537359
    Abstract: An object detector apparatus. The object detector apparatus comprises a receiver which is configured to receive a signal from an object having a repetitive motion, in which the signal repeats at a frequency that is dependent on the frequency of the repetitive motion of the object. The object detector apparatus further comprises an analyzer which is configured to sample a signal received by the receiver according to a first set of sampling parameters into a first sampled data set, and to produce an output based on a comparison of the first sampled data set with at least one previously sampled data set. The analyzer is also operable to sample a signal received by the receiver using a second set of sampling parameters which differs to the first set of sampling parameters into a second sampled data set, and to produce an output based on a comparison of the second sampled data set with at least one previously sampled data set.
    Type: Grant
    Filed: December 10, 2007
    Date of Patent: September 17, 2013
    Assignee: Renishaw PLC
    Inventors: Victor Gordon Stimpson, William Kenneth Davies, Benjamin Jason Merrifield, William Martin Barnard
  • Publication number: 20130220038
    Abstract: A method testing physical properties of bulk powder materials uses acceleration forces induce a change in physical configuration of a powder sample. Various different properties may be determined by relationships between the applied acceleration and the associated detected change in configuration event. In various embodiments powder strength, friction angle, or other properties may be determined. Novel methods and devices are provided.
    Type: Application
    Filed: December 18, 2012
    Publication date: August 29, 2013
    Applicant: Johanson Holdings LLC
    Inventor: Johanson Holdings LLC
  • Patent number: 8520193
    Abstract: Method for irradiating granules, in the case of which the granules are arranged in a sample container (2) and are irradiated with an irradiation lamp (3), the granules being periodically mixed during the irradiation such that different surfaces of the granules are irradiated. It is preferred to make use for the irradiation of a device which comprises a. at least one irradiation lamp (3), and b. at least one sample container (2) for the granules to be irradiated, the sample container being connected to a drive so that the sample container can be moved during the irradiation and the granules can be mixed.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: August 27, 2013
    Assignee: EVONIK DEGUSSA GmbH
    Inventors: Marisa Cruz, Rainer Fuchs, Frank Dieter Kuhn
  • Patent number: 8493557
    Abstract: A surface inspecting apparatus rotates a semiconductor wafer 100 (inspection object) as a main scan while translating the semiconductor wafer 100 as an auxiliary scan, illuminates the surface of the semiconductor wafer 100 with illuminating light 21, thereby forms an illumination spot 3 as the illumination area of the illuminating light 21, detects scattered or diffracted or reflected light from the illumination spot, and detects a foreign object existing on the surface of the semiconductor wafer 100 or in a part of the semiconductor wafer 100 in the vicinity of the surface based on the result of the detection. In the surface inspecting apparatus, the translation speed of the auxiliary scan is controlled according to the distance from the rotation center of the semiconductor wafer 100 in the main scan to the illumination spot.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: July 23, 2013
    Assignee: Hitachi High-Technologies Corporation
    Inventor: Shigeru Matsui
  • Patent number: 8355129
    Abstract: A method bulk strength of powders uses acceleration forces to compact the powder into a small conical test cell that is rotated at high speed. Once the material is consolidated to a prescribed condition, the rotation is stopped, the outlet of the cell is exposed, and the cell is rotated again at increasing acceleration until material freely exits the cell. The forces generated on the powder in the cell are determined and used to compute the cohesive strength of the bulk material.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: January 15, 2013
    Inventor: Kerry Johanson
  • Patent number: 8263955
    Abstract: Sensors can be used to obtain encoded sensing results from objects that have nonuniform relative motion. A photosensor or impedance-based sensor, for example, can obtain sensing results from objects that have relative motion within a sensing region relative to the sensor, with the relative motion being, for example, periodically varying, randomly varying, chirp-varying, or modulated relative motion that completes at least one modulation cycle within the sensing region. Relative motion can be caused by varying objects' speed and/or direction or by controlling flow of fluid carrying objects, movement of a channel, movement of a support structure, movement of a sensor, and/or pattern movement. A fluidic implementation can include shaped channel wall parts and/or a displacement component causing time-varying lateral displacement.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: September 11, 2012
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Peter Kiesel, Markus Beck, Michael Bassler, Noble M. Johnson
  • Publication number: 20120154809
    Abstract: A method bulk strength of powders uses acceleration forces to compact the powder into a small conical test cell that is rotated at high speed. Once the material is consolidated to a prescribed condition, the rotation is stopped, the outlet of the cell is exposed, and the cell is rotated again at increasing acceleration until material freely exits the cell. The forces generated on the powder in the cell are determined and used to compute the cohesive strength of the bulk material.
    Type: Application
    Filed: February 23, 2012
    Publication date: June 21, 2012
    Applicant: JOHANSON HOLDINGS LLC
    Inventor: Kerry Johanson
  • Patent number: 8064730
    Abstract: A method to determine a rotation of a substrate with respect to the patterning device without using a reference mark on the substrate is presented. At least two structures having corresponding features and present on the substrate, e.g. previously projected patterns, are imaged with a known position with respect to a measurement coordinate system. A distance vector between the at least two structures is determined. From the distance vector, a rotation angle is calculated. In an embodiment of the invention, there is provided a method to estimate a position of the substrate from the acquired image(s). A position is measured and used as a reference position for subsequent substrates of which the rotation angle is to be determined.
    Type: Grant
    Filed: September 8, 2004
    Date of Patent: November 22, 2011
    Assignee: ASML Netherlands B.V.
    Inventors: Raimond Visser, Leo Wilhelmus Maria Kuipers
  • Patent number: 8000515
    Abstract: A method and a device for inspecting surface coatings on workpieces, in particular of lacquer coatings, using an image capture and/or image processing system. The image capture and/or image processing system is designed to measure and/or process electromagnetic radiation from surface coating and/or a layer beneath it which is at least partially outside of the visible wavelength range.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: August 16, 2011
    Assignee: Robert Bosch GmbH
    Inventors: Thomas Brinz, Jane Lewis, Markus Tiefenbacher, Thomas Geiger, Tobias Burk
  • Patent number: 7997847
    Abstract: Systems and methods that process a plurality of surgical instruments for cleaning and/or packaging. A device identifies a robot-ready insert having a predetermined configuration for accepting at least one type of surgical instrument. The surgical instruments are identified and oriented according to type using an automated apparatus. Specialized tools are also provided for automatically opening and closing surgical instruments, flipping instruments and assisting in the processing and maintenance of surgical instruments. The automated apparatus then places each of the surgical instrument types in one or more predetermined areas of the insert, configured to accept a predetermined set of surgical instrument types.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: August 16, 2011
    Assignee: Robotic Systems & Technologies, Inc.
    Inventors: Michael R. Treat, David Michael Brady, Russell Baker, Jack M. Kaplan, David Berk
  • Patent number: 7957008
    Abstract: An optical-type rotational body position detection apparatus includes a body being rotational in a predetermined angle at each predetermined time interval to cross an optical axis between fixed light emitting and detecting units, including a standard position hole on a rotational locus crossing the axis, and configured such that after rotating the body at one interval from a standard position at which the hole coincides with the axis, a periphery of the hole is positioned outside the periphery at the standard position. The apparatus further includes a restriction unit on a support to cross the axis and to permit light passing and to restrict a diameter of the passing light. The restriction unit restricts the diameter of the passing light to be smaller than a minimum distance within a positional displacement tolerable error range of the hole after the predetermined angled rotation of the body.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: June 7, 2011
    Assignee: Casio Computer Co., Ltd.
    Inventor: Hiroyuki Hosobuchi
  • Patent number: 7710571
    Abstract: The invention relates to a spectroscopy system and improved membrane formation techniques. The system has at least one light source operable to generate a source beam and a prism having a rear surface. A support block is disposed on the rear surface of the prism. The support block is formed with at least one sample well having a center and defines a substantially vertical rear cell surface having a center. The source beam is aimed at the sample well. A syringe filled with a membrane solution and having a needle with a distal end disposed in front of the sample well. The distal end is aimed at a point above the center of the rear cell surface. The syringe is operable to eject a steady stream of membrane solution from the needle onto the circular rear cell surface thereby forming a membrane defining at least a portion of a layer under test. The membrane has a substantially uniform thickness that covers substantially the entire rear cell surface.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: May 4, 2010
    Assignee: Wyatt Technology Corporation
    Inventors: Glen Ramsay, David Anafi
  • Patent number: 7689003
    Abstract: An inspection apparatus (10) applying two dimensional nondestructive examination images onto a three dimensional solid model of a component (12) to display a virtual component (73) that may be manipulated to perform a nondestructive inspection. The two dimensional nondestructive examination images may be acquired from a plurality of views of the component in order to provide full coverage of the surface to be inspected, with appropriate stitching of images in regions of overlap between adjacent views. The two dimensional images (62) may be color or black and white photographs or ultraviolet or infrared images, for example. Multiple types of nondestructive examination images, results of inspection data evaluations, and design, operational and/or maintenance information may be displayed separately or jointly on the three dimensional solid model.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: March 30, 2010
    Assignee: Siemens Energy, Inc.
    Inventors: Robert E. Shannon, Clifford Hatcher, Claudio Laloni, Frank Forster, Fredrick M. Davis
  • Patent number: 7684054
    Abstract: A system and method are disclosed for inspecting a component having a length, a width, and an axis. The system includes a fixture for holding the component, a light source disposed on one side of the component, and an optical detector disposed on the other side of the component. In the preferred embodiment, the detector has a field of view wider than the width of the component, thereby enabling the detector to image a portion of the outer edges of the component. A translation stage is operative to move the light source and detector in unison along the length of the component and a processor, in communication with the detector and the translation stage, is operative to: a) receive electrical signals representative of the outer profile imaged by the detector; b) move the translation stage incrementally along the length of the component; and c) record the outer profile imaged by the detector at each increment and form a composite profile of the component.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: March 23, 2010
    Assignee: GII Acquisition, LLC
    Inventor: David Crowther
  • Patent number: 7667827
    Abstract: A system and method for monitoring the vibrations of a machine that includes a reflective patch affixed to the machine and a vibration detection unit including an optics module. The optics module may be positioned remotely from the machine such that the optics module transmits an electromagnetic beam to the reflective patch and reflected from the reflective patch to the optics module. The optics module demodulates the electromagnetic beam to determine the vibration of the machine.
    Type: Grant
    Filed: February 1, 2006
    Date of Patent: February 23, 2010
    Assignee: General Electric Company
    Inventors: Matthew Allen Nelson, Naresh Sundaram Iyer, John Erik Hershey, Charles Erklin Seeley, Piero Patrone Bonissone, Kai Frank Goebel
  • Patent number: 7580137
    Abstract: A method of determining one or more physical properties of a rolled smoking article is disclosed, the method comprising disposing a rolled smoking article within a field of view, illuminating the field of view, imaging the rolled smoking article to form an image, and analyzing the image to determine one or more physical properties of the rolled smoking article. Preferably the image is a digital image, which may be electronically processed to determine the physical properties. The physical properties may include the length of the rolled smoking article, or its mean diameter, ovality, circumference, roundness or shape. Also disclosed is an apparatus for performing such method comprising imaging means defining the field of view, means for positioning a smoking article in the field of view, illuminating means for illuminating the field of view, and processing means for processing the image to determine one more physical properties.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: August 25, 2009
    Assignee: Molins PLC
    Inventors: Ronald F. Wilson, Gary J. Pitt, Timothy G. Irons, William A. H. Everitt
  • Publication number: 20080158562
    Abstract: A process and device for dynamic measurement of the axial deformation of a rotating hollow shaft (10), a glass fiber segment (16) of a fiber optic sensor (18) being attached securely to a section of the inside wall of the hollow shaft (10) extending in axial alignment with the shaft. A light signal produced by a light source (24) is injected into the glass fiber segment (16), and the light signal being detected by a detector (28) after passing through the glass fiber segment (16). Axial deformation of the section of the inside wall of the hollow shaft (10) is ascertained by determining axial deformation of the glass fiber segment (16) from the change of at least one parameter of the light signal that occurs when the light signal passes through the glass fiber segment (16).
    Type: Application
    Filed: December 17, 2007
    Publication date: July 3, 2008
    Applicant: PRUEFTECHNIK DIETER BUSCH AG
    Inventor: Edwin BECKER
  • Patent number: 7274812
    Abstract: In an image processing device capable of collectively estimating an object based upon results of plural times of inspection, regions (1(1)) and (1(2)) to be photographed are defined on opposite end portions of an object (w). When an image of the left end portion of the object (w) is captured in response to a first trigger, the image processing device acquires corresponding image data, and the length (x1) of a projection extending in the x-direction at the left end of the object (w). When an image of the right end portion of the object (2) is next captured in response to a second trigger, the image processing device captures corresponding image data and measures the length (x2) of a projection extending in the x-direction at the right end of the work (w). Thereafter, the device finds the sum (x1+x2) of the lengths (x1, x2) inside, and outputs a result externally.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: September 25, 2007
    Assignee: Keyence Corporation
    Inventor: Kazuhito Saeki
  • Patent number: 7064314
    Abstract: A concrete-dispensing counter for ready mix trucks for measuring the volume of concrete discharged by a ready mix concrete truck. The concrete-dispensing counter for ready mix trucks includes a prime mover having a drum being rotatably mounted thereupon and also having a discharge chute through which cement is dispensed from the drum; and also includes a light emitting/reflecting assembly being mounted to the prime mover and including a plurality of light reflectors being spacedly attached about an exterior of the drum opposite to the discharge chute and also including a light-emitting member and a light-detecting member being mounted to the prime mover; and further includes a microprocessor being connected to the light-emitting and the light-detecting members; and also includes a concrete-dispensing sensor being attached to the discharge chute and to the light emitting/reflecting assembly and to the microprocessor for actuating the light emitting/reflecting assembly and the microprocessor.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: June 20, 2006
    Inventors: Jerome Poole, Anthony Poole, Jr., Lonita Poole
  • Patent number: 7057718
    Abstract: A method and a device of inspection of the transparent bottom of a bottle or similar item by using an optical system which shows the bottom of the bottle, for recording by a camera, in front of a surface which is illuminated by an illumination device, and the surface being located at a distance from the bottom of the bottle, whereby foreign bodies in the bottle can be detected. The illuminated surface can be the liquid level surface in the bottle, the bottom of foam in the bottle, or the bottom of the bottle closure member. The surface in the bottle can be illuminated from below or above the bottle.
    Type: Grant
    Filed: July 4, 2002
    Date of Patent: June 6, 2006
    Assignee: Krones AG
    Inventor: Rainer Kwirandt
  • Patent number: 6984526
    Abstract: A method and apparatus for characterizing the type of a blood sample and a variety of blood components are provided wherein a transmission spectrum of the sample is collected over a predetermined wavelength range. For blood typing, this spectrum is then compared with a set of control spectra collected from control blood samples having known blood types, from which the type of the blood sample can be determined. Further methods and apparatus are provided for determining the viability of and for cross matching a platelet unit. Additional method and apparatus permit analysis of the sample for the presence of a contaminant. Particles can also be counted in the sample, even when present in low concentrations, including white blood cell.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: January 10, 2006
    Assignee: University of South Florida
    Inventors: Luis Humberto Garcia-Rubio, Robert Potter, German Leparc, Sharyn Orton, Yvette Mattley, Christina Bacon
  • Patent number: 6775013
    Abstract: The degree to which a rotating object like a machine tool spindle undesirably wobbles in directions both transverse and parallel to its axis of rotation is measured preferably by providing a laser beam or other beam energy source which directs the beam toward a beam reflecting surface, most advantageously a curved surface, like a spherical or cylindrical surface. The reflecting surface is most advantageously formed by a spherical body mounted for adjustment in a plane perpendicular to the rotating axis involved, so that the center of the curved surface can be positioned as close as possible to the axis involved before error measurements are taken. In such case, the distance the beam traverses between the beam source and the point on the curved surface struck by the beam is a measure of the degree to which the spindle undesirably wobbles in directions both transverse to and parallel to the spindle axis.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: August 10, 2004
    Assignee: Optodyne, Inc.
    Inventor: Charles Wang
  • Patent number: 6653152
    Abstract: An optical assaying method and system having a movable sensor is described. In one aspect, the present invention is a sensing system having a rotating sensor disk coated with indicator dyes sensitized to a variety of substances. In this configuration the sensing system further includes a detector for sensing spectral changes in light received from one or more of the indicator dyes. In another aspect, the present invention is a sensing system having a surface plasmon resonance sensor disk having grooves extending radially from a center of the disk. In yet another aspect, the present invention is a sensing system including a diffraction anomaly sensor disk having a dielectric layer that varies in thickness. The present invention allows for construction of an inexpensive sensing system that is capable of easily detecting a variety of substances either in a sample or a surrounding environment.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: November 25, 2003
    Assignee: Imation Corp.
    Inventor: William A. Challener
  • Patent number: 6586172
    Abstract: The present invention relates to a method and apparatus for effective inactivation of micro-organisms in fluids with relatively high absorbance so as to limit damage. The apparatus has a large diameter passage (2) flow-through UV radiation system with a static mixer system (11) providing an intensive fluid flow mixing within an irradiation area in which the fluid flow is controlled to provide a flow rate not less than a minimum flow rate corresponding to a maximum fluid residence time within said irradiation area required for efficient mixing, and a maximum flow rate providing a minimum residence time for effective inactivation.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: July 1, 2003
    Assignee: Iatros Limited
    Inventors: Andrew Gunn, Ian David Cameron, Duncan Stephen Pepper, Shirley Lynn MacDonald, Qiangyi Li
  • Patent number: 6468807
    Abstract: The invention relates to a method for carrying out mixing in a thin liquid layer, which is arranged between essentially parallel walls at a capillary distance from each other. The mixing is carried out by subjecting the walls to a motion essentially in the plane of the liquid layer, balancing the motion against the capillary force exerted by the walls on the liquid, and selecting the interface between the liquid layer and the surrounding medium so that it functions as an elastic membrane. The invention also concerns a cuvette which is designed for mixing according to the method.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: October 22, 2002
    Assignee: Hemocue AB
    Inventors: Johnny Svensson, Bertil Nilsson, Per Olsson, Lars Jansson
  • Patent number: 6441890
    Abstract: Centrifuged material layer volumes are measured and quantified during centrifugation of the material layers contained in a sample tube in a centrifuge assembly, which sample tube is disposed on a centrifuge platen. The material layers in the sample tube are periodically illuminated during centrifugation by a pulsed light source which differentially excites one or more fluorescent dyes or stains which are admixed with the sample being analyzed. This kinetic procedure is particularly useful in performing differential blood cell and platelet counts. A fluorscent target reference device is positioned on the centrifuge platen along with a detectable platen position sensor. The centrifuge assembly includes a processor controller which receives information from the platen position sensor, and from the target reference device, and which controls operation of the light source.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: August 27, 2002
    Inventor: Stephen C. Wardlaw
  • Patent number: 6388740
    Abstract: Centrifuged material layer volumes are measured and quantified during centrifugation of the material layers contained in a sample tube in a centrifuge assembly, which sample tube is disposed on a centrifuge platen. The material layers in the sample tube are periodically illuminated during centrifugation by a pulsed light source which differentially excites one or more fluorescent dyes or stains which are admixed with the sample being analyzed. This kinetic procedure is particularly useful in performing differential blood cell and platelet counts. A fluorscent target reference device is positioned on the centrifuge platen along with a detectable platen position sensor. The centrifuge assembly includes a processor controller which receives information from the platen position sensor, and from the target reference device, and which controls operation of the light source.
    Type: Grant
    Filed: June 22, 1999
    Date of Patent: May 14, 2002
    Inventor: Stephen C. Wardlaw
  • Patent number: 6326213
    Abstract: A fluorescent fiber-optic biosensor system using ultrasonic concentration of particles and cells for the detection of Salmonella typhimurium. A biosensor test chamber serves as an ultrasonic standing-wave cell that allows microspheres or cells to be concentrated in parallel layers or in a column along the axis of the cell. A fiber probe along the axis delivers laser excitation to fluorescent-labeled antibodies of Salmonella and collects the fluorescent signal. The Salmonella-antibody complexes are moved acoustically to the axis of the cell, increasing the fluorescent signal. Alternatively, the Salmonella-labelled antibody complexes attach to unlabeled antibodies that have been immobilized on the surface of polystyrene microspheres. This entire structure can be manipulated acoustically and the increase in the fluorescent signal, which can be an order of magnitude, indicates the presence of Salmonella.
    Type: Grant
    Filed: February 9, 1998
    Date of Patent: December 4, 2001
    Assignee: The Boards of Govenors for Higher Education, State of Rhode Island and Providence Plantations
    Inventors: Stephen V. Letcher, A. Garth Rand, Chonghua Zhou
  • Patent number: 6317209
    Abstract: An apparatus for making automated measurements of an optical property of a sample includes a first stage which is movable along a predetermined line, a second stage for holding the sample, and a third stage which is movable along a predetermined line, correspondingly to the motion of the first stage. A light source is mounted on the first stage, and a light detector is mounted on the third stage. The second stage rotates the sample to a selected rotary position. The apparatus also includes a controller for coordinating movement of the first, second, and third stages such that the light source, the sample, and the light detector are optically aligned.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: November 13, 2001
    Assignee: Corning Incorporated
    Inventor: Richard S. Priestley
  • Patent number: 6306670
    Abstract: A system for flipping a semiconductor workpiece on its thin edge for microscope inspection of a workpiece facet is disclosed. The system has a holding device attached to a handling block. The holding device picks a workpiece by one of its thin edges. The edge of the workpiece may be attached to the holding device by vacuum. Then an operator rotates the handling block ninety degrees, which in turn rotates the holding device and workpiece ninety degrees. After rotation, one of the workpiece facets faces upward and perpendicular to the microscope for proper inspection of the facet.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: October 23, 2001
    Assignee: Lucent Technologies Inc.
    Inventors: Joseph Michael Freund, George John Przybylek, Dennis Mark Romero, John W. Stayt
  • Patent number: 6300142
    Abstract: A apparatus for assaying glycated proteins and other analytes in biological samples such as blood, in which a sample is presented to the apparatus, includes an inlet port between moveable between first and second inlets, such that the inlet can be brought into liquid communication with each inlet in turn. The inlet port accommodates a filter or binder. The apparatus also includes a microprocessor operable via a key pad, at least one light emitter and at least one light detector, a display and driver, and an A to D converter, and is operatively connected to a power source.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: October 9, 2001
    Assignee: Provalis Diagnostics LTD
    Inventors: David Andrewes, John Worthington Attridge, David Griffiths, John Phillip Vessey, John Anthony Odell, Felix Fernando, Anthony Stevenson, Mark Gresswell, John Curtis, David Alan Percival
  • Patent number: 6277653
    Abstract: An optical assaying method and system having a movable sensor is described. In one aspect, the present invention is a sensing system having a rotating sensor disk coated with indicator dyes sensitized to a variety of substances. In this configuration the sensing system further includes a detector for sensing spectral changes in light received from one or more of the indicator dyes. In another aspect, the present invention is a sensing system having a surface plasmon resonance sensor disk having grooves extending radially from a center of the disk. In yet another aspect, the present invention is a sensing system including a diffraction anomaly sensor disk having a dielectric layer that varies in thickness. The present invention allows for construction of an inexpensive sensing system that is capable of easily detecting a variety of substances either in a sample or a surrounding environment.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: August 21, 2001
    Assignee: Imation Corp.
    Inventors: William A. Challener, Richard R. Ollmann
  • Patent number: 6245578
    Abstract: An analytical apparatus comprises a biosensor device (3) which forms the base of a sample chamber. A stirrer (8) extends into the sample chamber and moves within the chamber so as to homogenize a sample contained within the chamber in contact with the biosensor (3). Movement of the stirrer (8) is preferably reciprocal movement along an axis perpendicular to the surface of the biosensor (3).
    Type: Grant
    Filed: February 23, 1998
    Date of Patent: June 12, 2001
    Assignee: Fisons PLC
    Inventor: James Oscar Molloy
  • Patent number: 6242267
    Abstract: An apparatus and method for rapidly analyzing samples for analytes of interest by an homogeneous immunofluorescence assay. The apparatus includes a sample test cartridge having a high control sample section, a low control sample section, and at least one test sample section. Each of these sections contain at least one pre-loaded reagent housed in a well within the cartridge wherein the low control sample section contains a known low amount of an analyte of interest and the high control sample section contains a known high amount of an analyte of interest. The cartridge includes a biosensor comprising a planar waveguide having first and second parallel plane surfaces and an edge extending between them, the edge having a receiving region for receiving a light beam.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: June 5, 2001
    Assignee: University of Utah Research Foundation
    Inventors: James N. Herron, Douglas A. Christensen, Scott D. Miles
  • Patent number: 6091503
    Abstract: A mechanical property such as axial acceleration of an injection molded resin disc substrate or an optical disc comprising the same is determined by measuring a variation in radius or diameter of the substrate or disc in its circumferential direction, and determining the mechanical property of the substrate or disc from the measurement.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: July 18, 2000
    Assignee: TDK Corporation
    Inventors: Isamu Kuribayashi, Hideki Hirata
  • Patent number: 6064475
    Abstract: An apparatus and method for determining local de-focus problems on a real time basis in a wafer exposure system. The distance of a wafer from an objective lens and rotation of the wafer about two orthogonal axis at each field position is adjusted to achieve optimum focus for each field of the wafer. The rotational data is fed to a computer and analyzed to determine if any of the rotational angles or if the difference between individual rotational angle and the mean rotational angle exceed critical angles. If any of the critical angles are exceeded local de-focus will occur and the exposure system must be checked for defects. If none of the critical angles are exceeded processing continues with the next wafer. The comparison of the rotational angles to the critical angles is performed for each wafer before continuing with the next wafer so that problems are discovered on a real time basis.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: May 16, 2000
    Assignee: Taiwan Semiconductor Manufacturing Company
    Inventors: Hung-Chih Chen, Yao-Chanet Chu, Tzu-Yu Lin, Chih-Chien Hung
  • Patent number: 6049388
    Abstract: A spectroscopic fluid sample cell for the transmission and detection of radiation with the key components being a housing; a centripetal acceleration chamber formed by the housing and extending through the housing for circulating a fluid through the housing over a curvilinear flow path about a rotational axis; a pair of windows aligned along a common axis intersecting a portion of the chamber and parallel to the rotational axis; a fluid inlet and a fluid outlet in communication with the centripetal acceleration chamber; and a flow director positioned in the housing to induce centripetal acceleration on fluid passing through the chamber and establish a radial composition gradient across the fluid chamber has been developed.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: April 11, 2000
    Assignee: UOP LLC
    Inventors: Brian K. Masterson, Terry R. Todd
  • Patent number: 6031933
    Abstract: The outer appearance of a golf ball (1) having a multiplicity of dimples (9) in its surface is inspected for detecting a defect (10) on the ball surface, by illuminating light to the golf ball (1), rotating the golf ball at a constant speed in one direction, operating a line sensor camera (4) to take a series of plurality of line images of the ball surface along a line (b) perpendicular to the rotational direction (a), the camera delivering image data including the line images, constructing a two-dimensional image from the image data, converting a brightness change appearing in the two-dimensional image in the rotational direction of the ball into a variation per preset unit, and subjecting the resulting variation data to binary processing on the basis of a threshold set between the variation associated with the dimple (9) and the variation associated with the defect (10), thereby detecting whether or not the defect (10) is present.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: February 29, 2000
    Assignee: Bridgestone Sports Co., Ltd.
    Inventor: Hiroki Kumagai
  • Patent number: 6025906
    Abstract: Methods and apparatus for detecting air/cladding and core/cladding interfaces of blanks (13) used to produce optical waveguide fibers are provided. A beam of coherent light (30) is scanning across the blank (13) and spatial light intensity patterns produced thereby (FIG. 5) are detected and analyzed. Air/cladding interfaces correspond to a decrease in the width of a unimodal spatial light intensity pattern as the beam moves towards the center of the blank (FIGS. 5A and 5B). Core/cladding interfaces correspond to the onset of an at least bimodal spatial light intensity pattern as the beam moves towards the center of the blank (FIGS. 5D and 5E). By rotating the blank and repeating the measurement process at two or more angular positions, concentricity and ellipticity values for a blank can be determined.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: February 15, 2000
    Assignee: Corning Incorporated
    Inventors: Jerry L. Hepburn, Franziska L. Lorey, David A. Pastel, Robert S. Wagner
  • Patent number: 5994150
    Abstract: An optical assaying method and system having a movable sensor is described. In one aspect, the present invention is a sensing system having a rotating sensor disk coated with indicator dyes sensitized to a variety of substances. In this configuration the sensing system further includes a detector for sensing spectral changes in light received from one or more of the indicator dyes. In another aspect, the present invention is a sensing system having a surface plasmon resonance sensor disk having grooves extending radially from a center of the disk. In yet another aspect, the present invention is a sensing system including a diffraction anomaly sensor disk having a dielectric layer that varies in thickness. The present invention allows for construction of an inexpensive sensing system that is capable of easily detecting a variety of substances either in a sample or a surrounding environment.
    Type: Grant
    Filed: November 19, 1997
    Date of Patent: November 30, 1999
    Assignee: Imation Corp.
    Inventors: William A. Challener, Richard R. Ollmann
  • Patent number: 5978091
    Abstract: An apparatus for measuring the height and diameter of laser-zone texture bumps on a rigid magnetic disk substrate is disclosed. The apparatus has a disk holder for supporting and rotating the substrate, and an optical beam-source assembly for directing a focused laser beam on the substrate, and for shifting the position of the beam's illumination spot on the substrate in a tracking (radial) direction. An optical detection assembly in the apparatus measures the deflection of the laser beam due to specular reflection of the beam by laser-zone texture bumps, as a function of time, in both scanning (circumferential) and tracking directions.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: November 2, 1999
    Assignee: HMT Technology Corporation
    Inventors: Peter C. Jann, Marco A. Krumbuegel, Reginald Lee, Ming M. Yang
  • Patent number: 5923431
    Abstract: A spectroscopic fluid sample apparatus for the transmission and detection of radiation with the key components being a housing; a helical bore formed by the housing and extending through the housing for conducting the sample fluid through the bore to induce centripetal acceleration on the sample fluid and establish a radial composition gradient across the sample fluid in the bore; a fluid inlet and a fluid outlet each in fluid communication with the helical bore; and a spectroscopic sample interface in fluid communication with the fluid outlet has been developed.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: July 13, 1999
    Assignee: UOP LLC
    Inventors: Brian K. Masterson, Terry R. Todd
  • Patent number: 5854682
    Abstract: The present invention provides a new synchronized optical method for measuring surface pressure on rotating objects such as propellers or other rotating objects. The technique is based on the phenomenon of oxygen quenching of luminescence coatings and synchronized optical imaging. A surface coating, referred to as a pressure sensitive paint (PSP), is formed by mixing photo-luminescence molecules in an oxygen permeable polymer. The luminescence excited by an appropriate light source decreases as the oxygen concentration rises due to quenching. As a result, the luminescence intensity of light emitted from the coating varies as a function of the partial pressure of oxygen. A digital camera measures the luminescence intensity distribution over the object and the pressure distribution can be computed.
    Type: Grant
    Filed: May 1, 1997
    Date of Patent: December 29, 1998
    Inventor: Xijia Gu