Abstract: A discrimination system that forms a fluid column and interrogates objects within the fluid column with an excitation source. An optical arrangement collects output electromagnetic radiation emanating from the excited objects disposed within the fluid column and directs the output electromagnetic radiation to a detector. An analyzer reduces the positional dependency of the detected intensity by normalizing the value based on the position of each object.

Abstract: Provided in the disclosure is a photomask for detecting flare degree of lens of exposure machine. The photomask includes a central exposure area and a peripheral area, exposure light of the exposure machine passing through the lens and then penetrating the central exposure area to expose photoresist on a wafer, wherein the entire central exposure area is provided with a shading layer to prevent the exposure light from penetrating; and the peripheral area is provided with a plurality of light-transmitting stripes, and stray light formed after the exposure light passes through the lens penetrates the plurality of light-transmitting stripes to expose the photoresist. Further provided in the disclosure is a method for detecting flare degree of lens of exposure machine by using the photomask. According to the disclosure, a lens flare problem of an exposure machine can be found and solved in time.

Abstract: By way of overview and introduction, various embodiments of the apparatus, systems and methods described herein are directed improved approaches to aligning and standardizing different total spectral radiance factor shapes measured with different instruments. Furthermore, in one or more configurations and approaches, the disclosure presented herein is directed to obtaining a whiteness calibration value for use in sample measurements without the need of UV filter adjustments.

Abstract: A device for fluid analysis including an integrated computational element (ICE), a sample cell that optically interacts the ICE with a sample to generate a computation light associated with a characteristic of the sample, and a fiber sensor that receives the computation light and converts the computation light into a heat, is provided. The fiber sensor is coupled with a detector through an optical link, and is configured to return a portion of probe light through the optical link to the detector based on the heat converted. A method for using the device for performing fluid analysis is provided. A system for fluid analysis including at least one device as above is also provided.

Abstract: This disclosure describes an additive manufacturing system that includes a build plane having a first region and a second region. Multiple energy source can be positioned above the build plane and configured to direct energy into the first and second regions of the build plane. The system includes optical sensors configured to monitor an intensity of light emitted from the energy sources. A processor associated with the additive manufacturing system is configured to adjust the sensor outputs in response to the energy sources coming into close proximity.

Abstract: A gas analysis system includes a spectroscopy assembly coupled to a vehicle. The spectroscopy assembly includes a multiplexer configured to combine a plurality of light beams into a multiplexed light beam, wherein the multiplexer is configured to direct the multiplexed light beam toward a target surface. Additionally, the spectroscopy assembly includes a collection optic configured to receive a reflected multiplexed light beam from the target surface. Further, the spectroscopy assembly includes a controller configured to de-multiplex the multiplexed light beam into a plurality of reflected light beams and determine a spectral intensity of the plurality of reflected light beams.

Abstract: A maturity determination device includes an image capturing device including a plurality of pixels arrayed one-dimensionally or two-dimensionally, the image capturing device performing image capturing of at least a part of a fruit or vegetable product to acquire an image, the plurality of pixels including a plurality of first pixels each including a first light transmission filter selectively transmitting light of a first wavelength band, the intensity of the light of the first wavelength band reflected by the fruit or vegetable product varying in accordance with a maturity level; and a signal processing circuit configured to find an area size ratio of an intensity distribution of the light of the first wavelength band on the basis of a predetermined reference value based on a pixel value obtained from the plurality of first pixels, and to generate maturity determination information in accordance with the area size ratio.

Abstract: Systems and methods for detecting a biological analyte are provided. The biological analyte can be, for example, cortisol. Detection can be achieved without external labels/mediators. Microfluidic systems can be incorporated into the optical sensor for enhanced point-of-care applications. The sensor can be used in a variety of low-power electronics for wearable applications.

Abstract: Detection sensitivity of optical computing devices may be improved by utilizing multiple integrated computational elements in combination with one another. Optical computing devices containing multiple integrated computational elements may comprise: two or more integrated computational elements that are identical to one another and optically interact sequentially with incident electromagnetic radiation, such that at least a portion of the photons from the incident electromagnetic radiation optically interacts with each integrated computational element; wherein the sequential optical interaction of the incident electromagnetic radiation with the two or more integrated computational elements increases a detection sensitivity of the optical computing device relative to that obtained when only one of the integrated computational elements is present; and a detector that receives the photons that have optically interacted with each integrated computational element.

Abstract: The invention relates to an apparatus (1) for producing short synchronous radiation pulses at different wavelengths, particularly to an optically parametric oscillator, comprising at least one pump radiation source (2), preferably a pump laser, for outputting radiation at a pump wavelength, and a resonator (3) having a wavelength-dependent effective resonator length, wherein the resonator (3) has a non-linear wavelength converter (4) for producing radiation at a first and a second wavelength; a dispersive element (5) having a strong wavelength-dependent delay characteristic; and a coupling-out element (6) for at least partially coupling-out the radiation from the resonator (3). In addition, the invention relates to a method for producing short radiation pulses by means of an apparatus (1), particularly an optically parametric oscillator.

Abstract: Provided is a test apparatus including an optical test signal generating section that generates an optical test signal; an optical signal supplying section that supplies the optical test signal to a device under test that is a testing target among a plurality of the devices under test; a first optical switch section that selects, from among optical signals output by the plurality of devices under test, the optical signal output by the device under test that is the testing target; and an optical signal receiving section that receives the selected optical signal.

Abstract: There is described a distributed optical fibre sensor for detecting one or more physical parameters indicative of an environmental influence on a sensor optical fibre, as a function of position along the sensor fibre. The sensor uses probe light pulses of different wavelengths. At least some of the probe light pulses may also be of different pulse lengths. The relative phase bias between interferometric signals in backscattered probe light of different wavelength pulses may also be controlled.

Abstract: Determination of an underlying grid structure that facilitates layout of East Asian text is disclosed. The underlying grid structure includes both a size of character frames and a size of a text block frame. The East Asian text may be obtained from a scan of printed material that has the text formatted according to layout conventions established by the publisher. The text may be reformatted to appear on a display of an electronic device in a manner similar to the formatting in the original scanned document. Reformatting may include reflowing the text in order to fit a greater or lesser number of characters on a line. The reflowing may maintain character spacing from the original document and follow formatting rules against locating certain characters at the start or end of a line.

Abstract: The present invention relates to the sample preparation of nucleic acids for diagnostic purposes. More precisely, the invention provides a process for simultaneously isolating at least a first and a second target nucleic acid from a plurality of different types of fluid samples and optionally amplifying said isolated nucleic acids in a simultaneous manner.

Abstract: A micro-electro-mechanical (MEMS) based surveillance system and a method for using the MEMS based surveillance system are described herein for imaging an object. In one example, the MEMS based surveillance system can record images of an object from four different wavelength regions including visible light, near-infrared light, infrared light, and far infrared light.

Abstract: A sensor device configured to be attached to a drug delivery device and configured to illuminate the drug delivery device when attached, the sensor device having an OLED having a transparent first electrode, a transparent second electrode and a central layer disposed between the first and second electrodes, the central layer comprising at least one organic layer, the at least one organic layer configured to emit light through the transparent first electrode, and an optical sensor arranged to receive light reflected from a surface of the drug delivery device, wherein the central layer of the OLED has a region without the at least one organic layer and wherein the optical sensor is arranged, when the sensor device is attached to the drug delivery device, to view a predetermined area of the surface of the drug delivery device through the region without the at least one organic layer.

Abstract: An atmosphere profiling system is disclosed. The atmosphere profiling system is configured to characterize optical properties of the atmosphere.

Abstract: A method for non-invasively determining a chemical property of an aqueous solution is provided. The method provides the steps of providing a colored solute having a light absorbance spectrum and transmitting light through the colored solute at two different wavelengths. The method further provides the steps of measuring light absorbance of the colored solute at the two different transmitted light wavelengths, and comparing the light absorbance of the colored solute at the two different wavelengths to determine a chemical property of an aqueous solution.

Abstract: A reference harmonic absorption curve of a laser absorption spectrometer can have a reference curve shape derived from a reference signal generated by the detector in response to light passing from the laser light source through a reference gas or gas mixture. The reference gas or gas mixture can include one or more of a target analyte and a background gas expected to be present during analysis of the target analyte. A test harmonic absorption curve having a test curve shape is compared with the reference harmonic absorption curve to detect a difference between the test curve shape and the reference curve shape. Operating and/or analytical parameters of the laser absorption spectrometer are adjusted to correct the test curve shape to reduce the difference between the test curve shape and the reference curve shape.

Abstract: An invention for making productive uses of normally undesirable whiskers is provided. Embodiments of the invention include a variety of apparatuses and methods associated with forming and using whiskers as well as forming whisker compounds is disclosed. For example, whisker detection modules can be created which provide a whisker surveillance capability. The whisker detection modules can further be coupled with a whisker response system such as an alarm or insulating material dispersing system. Another aspect of the invention is providing a variety of environments or microenvironments with regard to a whisker forming structure to affect whisker creation such as maximizing whisker formation. Another example includes provision of a variety of embodiments for manufacturing compounds of whiskers of various metal and metal alloys, including structures and methods is provided. Whisker compounds produced using various embodiments of the invention can be used for various applications.

Abstract: Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.

Abstract: A security document is disclosed which includes an electrical circuit embedded in a document substrate, where the electrical circuit includes a power source with at least one electroactive polymer power generator, and an optical display including at least one electroluminescent display element and at least one nanohole array which forms a layer of the electroluminescent display element. Security features comprising nanohole arrays are also provided. A method of authenticating a security document is disclosed, including illuminating an encoded nanohole array in the security document with a focused light beam or laser light source emitting at least one defined wavelength of incident light, detecting a transmitted portion of the incident light transmitted through the nanohole array with an optoelectronic sensor, analyzing at least one wavelength of the transmitted portion of light to produce a detected signal, and comparing the detected signal with an authentication signal to authenticate the security document.

Abstract: Methods, articles of manufacture, and kits for calibrating fluid delivery systems are provided. A fluid delivery system connected to N input streams, where N is an integer greater than or equal to 2, mixes together fluid from the N input streams to form an output stream. The methods involve obtaining N test solutions, each containing a dye, providing optical absorbances of the test solutions at appropriate wavelengths, injecting the test solutions into the input streams, mixing the test solutions, and measuring the absorbance of the output stream at the same wavelengths. The methods also involve comparing the absorbances of the test solutions with the absorbances of the output stream, which can include calculating ratios and comparing the ratios with target values. The methods can further involve adjusting operation of the fluid delivery system based upon the absorbances. In some embodiments, the dyes have largely non-overlapping absorbance spectra.

Abstract: A spectroscopic sensor and a spectroscopic method of determining a concentration of a sample are disclosed. The sensor is used in connection with a sample cell containing a sample. The sensor includes a coherent light source configured to transmit an interrogation light beam along an optical sample path directed towards the sample. The sensor also includes an in-line reference cell located in the sample path. The sensor also includes a detector having outputs responsive to absorption signals from the sample and the in-line reference cell. The sensor also includes a processor configured to isolate the reference absorption signals from the in-line reference cell and sample absorption signals from the sample cell and generate calibration information based on the reference absorption signals and determine a concentration of the sample based on the sample absorption signals.

Abstract: A method of providing an indication as to the amount of milk remaining in a breast during lactation based on a determined fat content of milk that has been expressed from said breast is disclosed. The method of determining said fat content comprises measuring an optical characteristic of milk following expression and by comparing said measured optical characteristic with data representing a corresponding optical characteristic of a sample of milk having a known fat content to determine the fat content of said expressed milk which is indicative of the amount of milk remaining in the breast.

Abstract: A gas detector including: an assembly of two coaxial parabolic reflective caps having opposite concavities, and a wafer arranged in the focal plane of the two caps, at the center of this focal plane, comprising, back-to-back: a diverging light emitter directed towards the first cap and a light receiver directed towards the second cap, wherein the two caps are distant substantially by the sum of their focal distances plus the thickness of the wafer.

Abstract: There is provided a microparticle measurement apparatus including a first light source configured to irradiate excitation light on a droplet containing a microparticle, the droplet being discharged from an orifice, a second light source configured to irradiate illumination light on the droplet for acquiring an image of the droplet, a light receiving element configured to detect fluorescence generated from the microparticle due to the irradiation of the excitation light, and to acquire an image of the droplet, and a filter member configured to be arranged between the droplet and the light receiving element. The filter member includes a first area through which the fluorescence and the illumination light pass, and a second area that is provided around the first area and that has a wavelength selectivity which lets the fluorescence pass through but blocks the illumination light.

Abstract: In certain embodiments, a system for detecting an agent includes a resonator device configured to receive an agent. The resonator device is also configured to transmit light received from a light source, the transmitted light having an altered peak wavelength due to the presence of the received agent. The system further includes a filter device configured to filter the transmitted light having the altered peak wavelength such that the transmitted light having the altered peak wavelength does not reach one or more detectors of a detector array configured to receive transmitted light not filtered by the filter device. The system further includes a processing system operable to determine that the one or more detectors of the detector array are not generating a signal, the absence of the signal being generated by the one or more detectors of the detector array indicating the presence of the agent.

Abstract: An absorption measurement system, flexibly usable over a large measuring range, for measuring at least one property of a medium reflected in its absorption behavior, especially a property such as an absorption coefficient (?). The absorption measurement system comprises: a measuring chamber filled with the medium in measurement operation, in which radiatable beam paths usable as measuring paths and of different lengths, extend completely through the medium; a transmitting unit, which transmits radiation along the measuring paths through measuring chamber in measurement operation; a measuring and receiving unit, which receives radiation passing through measuring chamber on the measuring paths and measures its radiation intensities dependent on the property of the medium and the lengths of the measuring paths; and a measuring electronics, which determines the property based on the measured radiation intensities and the lengths of measuring paths.

Abstract: A device, system, and method for measuring acetone levels exhaled from a patient and correlating the measured level to a blood glucose concentration.

Abstract: A spectrometer cell can include a spacer, at least one end cap, and at least one mirror with a reflective surface. The end cap can be positioned proximate to a first contact end of the spacer such that the end cap and spacer at least partially enclose an internal volume of the spectrometer cell. The mirror can be secured in place by a mechanical attachment that includes attachment materials that are chemically inert to at least one reactive gas compound. The mechanical attachment can hold an optical axis of the reflective surface in a fixed orientation relative to other components of the spectrometer cell and or a spectrometer device that comprises the spectrometer cell. The mirror can optionally be constructed of a material such as stainless steel, ceramic, or the like. Related methods, articles of manufacture, systems, and the like are described.

Abstract: Methods and apparatuses for measuring a light absorbance are provided. The method measures light absorbance of at least one detection chamber of a microfluidic device, including the detection chamber and at least one reference chamber. The detection chamber may accommodate a test subject. The method includes detecting a plurality of reference transmitted light intensities for the at least one reference chamber and estimating a value between the plurality of reference transmitted light intensities through nonlinear approximation. The estimated value is then applied to light absorbance measurement of the detection chamber to reduce a light absorbance error of the detection chamber.

Abstract: Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.

Abstract: A system, apparatus, and method is provided to remotely measure atmospheric species using a long path differential absorption technique. In one embodiment, a source and a detector are collocated and at the far end of the absorption path a retro-reflector is mounted on a vehicle. The source generates an outgoing laser beam that is transmitted to the retro-reflector and reflected towards the detector as an incoming laser beam, and the detector receives the incoming laser beam that was reflected by the retro-reflector.

Abstract: Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

Abstract: The present invention provides a transmissive density and/or reflective density reference step tablet and methods of using thereof for calibrating a densitometer or the like.

Abstract: An array of light sources (lasers) is positioned so that each of the light sources emits a beam that is directed through a sedimenting column of ground grain. Photodetectors (photodiodes) positioned opposite the light sources receive the light beams emerging from the sedimenting column and convert the beams into electronic signals. A computer processor processes the electronic signals and generates values for protein quality.

Abstract: Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample.

Abstract: An OPO is disclosed capable of rapid frequency tuning by non-mechanical means. The OPO includes a resonant cavity including one or more non-linear crystals in an optical path thereof. A pump laser pulse is transmitted into the resonant cavity simultaneously with a seed beam having a desired wavelength. The output beam from the resonant cavity has the same center wavelength as the seed beam. The wavelength of the seed beam may be modulated at a frequency larger than the pulse rate of the pump laser or larger than the inverse of the pulse duration. The OPO disclosed may be used to perform DIAL analysis wherein intra-pulse modulation of an output beam is used to obtain measurements of absorption at multiple frequencies for each pulse of a pump beam.

Abstract: A process for evaluating a cleaning solution is described. The process includes: (a) subjecting a solution, including a solute and a solvent, to sonic energy to create a sonicated solution; (b) measuring UV absorption of the sonicated solution to produce a sample UV absorbance spectra; (c) obtaining a reference UV absorbance spectra; (d) scaling the reference UV absorbance spectra to the sample UV absorbance spectra at a lower range of the UV spectrum; (e) subtracting from the reference UV absorbance spectra the sample UV absorbance spectra to produce a differential UV spectra; and (f) evaluating at or near a peak of the sample UV absorbance spectra the differential UV absorbance spectra to determine whether the sonicated solution is activated.

Abstract: An optical absorption gas analyzer is provided for determining the concentration of a target gas in a sample, comprising: a chamber for containing the sample in use; an optopair, comprising a light emitting diode (LED) arranged to emit radiation into the chamber and a photovoltaic radiation detector arranged to detect radiation transmitted through the chamber from the LED and to output a corresponding detection signal SS; a temperature sensor arranged in thermal contact with the LED and the photovoltaic radiation detector, and to output a temperature signal T representing the temperature of the optopair; a memory having stored therein data representative of the baseline detection signal ST output by the optopair in the absence of the target gas as a function of the temperature of the optopair across a range of temperatures; and a processor adapted to generate a differential detection signal SA indicative of the concentration of target gas in the sample by retrieving from the memory the baseline detection sign

Abstract: An optical measurement method for high-speed acquisition of integral transformed time domain optical signals is presented. A circuit network is used to generate a modulation signal and a reference signal from a broadband signal such as a pseudo random bit sequence. The integral transformed measurements are obtained by cross correlating the time dependent response to the modulated illumination with the reference signal.

Abstract: Improved scanner designs are provided to improve imaging and reduce errors during the scanning process. Embodiments disclosed include, for example, the use of dual cameras to improve imagery and reduce the scanner enclosure size, synchronized lighting techniques during the scanning sequence, shielded lens for the camera scanner, a scanner enclosed on at least three sides, adjustments to scanner lighting based on the levels of ambient lighting, a combined branding and scanner apparatus, a gimbaled scanner mount, and a tilted platen with stop for document alignment.

Abstract: In certain embodiments, a system for detecting an agent includes a resonator device configured to receive an agent. The resonator device is additionally configured to transmit light received from a light source. The transmitted light has a known characteristic in the absence of the received agent and an altered characteristic in the presence of the received agent. The system further include a lens positioned between the resonator device and a detector array. The lens is configured to focus the transmitted light onto one or more detectors of the detector array, the one or more detectors of the detector array operable to generate a signal corresponding to the transmitted light. The system further includes a processing system operable to determine whether the agent is present based on the signal generated by the one or more detectors of the detector array.

Abstract: The present invention creates a spectrometer (1; 1?) for measuring the concentration of at least one analyte in a fluid sample (2; 2?), with a light source (3; 3?) to generate a light beam (4; 4?), with a photosensor (5; 5?) to receive the light beam (4; 4?), and with a measurement length (6; 6?), in which the fluid sample (2; 2?) can be placed, in the beam path of the light beam (4; 4?), the measurement length (6; 6?) being provided in changeable form.

Abstract: An in vivo drug concentration distribution measuring device for measuring, when a drug having an imaging function is administered, in vivo concentration distribution of the drug is disclosed.

Abstract: A method for detecting a target analyte associated with nano-sized gold- and/or silver-containing detecting labels in a microarray of samples. The labels indicate presence or absence of a target analyte in a sample. The method includes sequentially illuminating at least two sample groups with at least two different monochromatic light beams. The sample groups include (a) a first sample group containing at least one sample potentially containing the target analyte, and (b) a second sample group serving as positive control or negative control. The method also includes (ii) detecting intensity of light reflected, absorbed, or emitted from each of the sample groups when illuminated with each of the monochromatic light beams. (iii) recording groups of values associated with the intensity reflected, absorbed, or emitted light. (iv) comparing the groups of values associated with the sample groups; and (v) determining the presence of the target analyte based on the comparison.

Abstract: Methods and apparatuses for measuring a light absorbance are provided. The method measures light absorbance of at least one detection chamber of a microfluidic device, including the detection chamber and at least one reference chamber. The detection chamber may accommodate a test subject. The method includes detecting a plurality of reference transmitted light intensities for the at least one reference chamber and estimating a value between the plurality of reference transmitted light intensities through nonlinear approximation. The estimated value is then applied to light absorbance measurement of the detection chamber to reduce a light absorbance error of the detection chamber.

Abstract: When assessing the start time of the limulus reaction between biogenous biologically active substances and LAL and using the reaction start time to determine the concentration of the biogenous biologically active substances, in order to exclude the influence of progressive changes which occur regardless of the conditions of the limulus reaction, the strength of transmitted light or scattered light in the liquid mixture of the measurement sample and LAL is detected, the variation (delta) in the transmittance or number of gel particles is acquired at set intervals, and the time when the variation (delta) crosses a threshold value is taken as the reaction start time. Furthermore, the time intervals when acquiring the abovementioned delta are not uniform, and either change over time from the start of measurement as defined by a time function, or multiple sequences with differing time intervals are prepared in advance.

Abstract: A system, apparatus, and method is provided to remotely measure atmospheric species using a long path differential absorption technique. In one embodiment, a source and a detector are collocated and at the far end of the absorption path a retro-reflector is mounted on a vehicle. The source generates an outgoing laser beam that is transmitted to the retro-reflector and reflected towards the detector as an incoming laser beam, and the detector receives the incoming laser beam that was reflected by the retro-reflector.