Deuterium-containing Patents (Class 423/647.7)
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Patent number: 10940437Abstract: A liquid phase catalytic exchange column with a catalyst is configured to receive hydrogen gas. The system uses the catalyst to exchange the hydrogen gas with the tritiated source yielding HT gas and tritiated water. The system monitors tritium content of the tritiated water. When a predetermined tritium level is detected, the tritiated water is released. The system also includes a gaseous permeation system comprising a permeable barrier for the selective extraction of gases.Type: GrantFiled: June 2, 2016Date of Patent: March 9, 2021Assignee: Veolia Nuclear Solutions, Inc.Inventors: Mark S. Denton, Gaetan Bonhomme, Wesley L. Bratton, Nicephore Bonnet
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Patent number: 9455056Abstract: A method of collecting 3He from a nuclear reactor may include the steps of a) providing heavy water at least part of which is exposed to a neutron flux of the reactor, b) providing a cover gas in fluid communication with the heavy water, c) operating the nuclear reactor whereby thermal neutron activation of deuterium in the heavy water produces tritium (3H) and at least some of the tritium produces 3He gas by ?? decay and at least a portion of the 3He gas escapes from the heavy water and mixes with the cover gas, d) extracting an outlet gas stream, the outlet gas stream comprising a mixture of the cover gas and the 3He gas and e) separating the 3He gas from the outlet gas stream.Type: GrantFiled: March 28, 2013Date of Patent: September 27, 2016Assignee: Atomic Energy of Canada Limited/Énergie Atomique du Canada LimitéeInventors: Bhaskar Sur, Lakshman Rodrigo, Richard Didsbury
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Publication number: 20150034500Abstract: A metal organic framework (MOF) includes a coordination product of a metal ion and an at least bidentate organic ligand, where the metal ion and the organic ligand are selected to provide a deliverable adsorption capacity of at least 70 g/l for an electronic gas. A porous organic polymer (POP) includes polymerization product from at least a plurality of organic monomers, where the organic monomers are selected to provide a deliverable adsorption capacity of at least 70 g/l for an electronic gas.Type: ApplicationFiled: August 4, 2014Publication date: February 5, 2015Inventors: Han Sung KIM, Mitchell Hugh WESTON, Patrick FULLER, Paul Wai-Man SIU
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Publication number: 20150025264Abstract: Objects are to provide efficient methods for producing hydrogen or heavy hydrogens and for hydrogenating (protiating, deuterating or tritiating) an organic compound, and to provide an equipment and the like used therefor. A method for producing hydrogen or heavy hydrogens, containing subjecting water or heavy water to mechanochemical reaction in the presence of a catalyst metal, in which an energy density of a rotational acceleration of 75 G or more is applied to water or heavy water for 25 minutes or more, a method for producing a hydrogenated (protiated, deuterated or tritiated) organic compound, a method for hydrogenating (protiating, deuterating or tritiating) an organic compound, a method for dehalogenating an organic compound having halogen, and a ball for mechanochemical reaction are provided.Type: ApplicationFiled: February 8, 2013Publication date: January 22, 2015Applicant: Shiono Chemical Co., Ltd.Inventors: Hironao Sajiki, Yasunari Monguchi, Yoshinari Sawama, Shinichi Kondo, Yasushi Sasai
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Publication number: 20140363369Abstract: An object is to provide a process for providing hydrogen or heavy hydrogens conveniently without the necessity of large-scale equipment and a process capable of performing hydrogenation (protiation, deuteration or tritiation) reaction conveniently without the use of an expensive reagent and a special catalyst. The production process includes a process for producing hydrogen or heavy hydrogens, containing subjecting water or heavy water to mechanochemical reaction in the presence of a catalyst metal, and a process for producing a hydrogenated (protiated, deuterated or tritiated) organic compound, containing subjecting an organic compound and water or heavy water to mechanochemical reaction in the presence of a catalyst metal.Type: ApplicationFiled: August 14, 2014Publication date: December 11, 2014Applicant: Shiono Chemical Co., Ltd.Inventors: Hironao SAJIKI, Yasunari MONGUCHI, Yoshinari SAWAMA, Shinichi KONDO
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Patent number: 8801963Abstract: The present invention relates to a process for the preparation of stannane and deuterostannane by reacting a stannic halide with lithium aluminum hydride or aluminum deuteride respectively in a polydentate solvent.Type: GrantFiled: August 10, 2011Date of Patent: August 12, 2014Assignee: Voltaix, LLCInventor: Cole J. Ritter, III
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Publication number: 20140099252Abstract: An approach for supplying hydrogen and/or deuterium to LENR and E-Cat based energy generating systems includes receiving a source material that is rich in hydrogen and/or deuterium. A gaseous form of at least one of those elements is extracted from the source material via electrochemical dissociation, hydrocarbon recovery, or a suitable mechanical process. The gaseous form of the element is preferably filtered to remove water vapor and other impurities before being pressurized and supplied to the energy generating system. Advantages of the approach include enhanced safety and system portability due to elimination of a need for pressurized gas storage tanks.Type: ApplicationFiled: October 9, 2012Publication date: April 10, 2014Inventors: Marc Kenneth Chason, Daniel Roman Gamota, Rick Latella
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Patent number: 8592487Abstract: This invention relates to novel compounds that are hydroxyethylamino sulfonamide derivatives and pharmaceutically acceptable salts thereof. More specifically, this invention relates to novel hydroxyethylamino sulfonamide derivatives that are derivatives of darunavir. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering a human immunodeficiency virus (HIV) protease inhibitor, such as darunavir.Type: GrantFiled: April 28, 2009Date of Patent: November 26, 2013Assignee: Concert Pharmaceuticals, Inc.Inventor: Scott L. Harbeson
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Patent number: 8470073Abstract: The apparatus and process for separating hydrogen isotopes is provided using dual columns, each column having an opposite hydrogen isotopic effect such that when a hydrogen isotope mixture feedstock is cycled between the two respective columns, two different hydrogen isotopes are separated from the feedstock.Type: GrantFiled: September 15, 2010Date of Patent: June 25, 2013Assignee: Savannah River Nuclear Solutions, LLCInventors: Leung K. Heung, Henry T. Sessions, Xin Xiao
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Patent number: 8440165Abstract: A method includes operating a gas loading system with a source of one or more isotopes of hydrogen, a gas loading chamber containing a number of metallic nanoparticles, the metallic nanoparticles being selected to provide for a predetermined hydrogen cluster formation density, a vacuum system, and a valve system in communication with the gas loading chamber, the source of one or more isotopes of hydrogen and the vacuum system; providing the gas loading chamber with a first quantity of the one or more isotopes of hydrogen from the source of one or more isotopes of hydrogen; monitoring an operating temperature; and cycling a loading pressure of the gas loading chamber using the source of one or more isotopes of hydrogen in response to providing the gas loading chamber and monitoring the operating temperature.Type: GrantFiled: March 7, 2012Date of Patent: May 14, 2013Assignee: NPL Associates, Inc.Inventors: George H. Miley, Xiaoling Yang
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Patent number: 8313726Abstract: A gas generator includes a processing vessel defining a processing space and holding a support body therein, an evacuation system evacuating the processing space; a metal oxide film of a perovskite structure containing oxygen defects formed on the support body, a source gas supplying port supplying a source gas containing molecules of a source compound of carbon dioxide or water into the processing space, a gas outlet port for extracting a product gas containing molecules of a product compound in which oxygen atoms are removed from said source compound, and a heating part heating the support body.Type: GrantFiled: November 9, 2011Date of Patent: November 20, 2012Assignee: Fujitsu LimitedInventors: John David Baniecki, Masatoshi Ishii, Kazuaki Kurihara, Kazunori Yamanaka
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Publication number: 20120164063Abstract: A method includes operating a gas loading system with a source of one or more isotopes of hydrogen, a gas loading chamber containing a number of metallic nanoparticles, the metallic nanoparticles being selected to provide for a predetermined hydrogen cluster formation density, a vacuum system, and a valve system in communication with the gas loading chamber, the source of one or more isotopes of hydrogen and the vacuum system; providing the gas loading chamber with a first quantity of the one or more isotopes of hydrogen from the source of one or more isotopes of hydrogen; monitoring an operating temperature; and cycling a loading pressure of the gas loading chamber using the source of one or more isotopes of hydrogen in response to providing the gas loading chamber and monitoring the operating temperature.Type: ApplicationFiled: March 7, 2012Publication date: June 28, 2012Inventors: George H. Miley, Xiaoling Yang
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Patent number: 7815890Abstract: A diffusion based process for tritium removal from water by tritium transfer from water to an elemental hydrogen stream, followed by a membrane diffusion cascade for tritium stripping and enrichment, and final tritium enrichment by one or more thermal diffusion columns. The combination of process steps takes advantage of membrane diffusion's large throughput capability at low tritium concentration with the simplicity of thermal diffusion for small throughput final tritium enrichment. The membrane diffusion stages use supported or unsupported microporous or hydrogen permeable metal membranes (such as Pd/Ag alloy). The diffusion process is compatible with any front-end process to transfer tritium from tritiated water to elemental hydrogen. The process may be designed and operated at low pressure, with small gas inventory, and no inherent overpressure hazard.Type: GrantFiled: October 11, 2005Date of Patent: October 19, 2010Assignee: Special Separations Application, Inc.Inventor: Anthony Busigin
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Patent number: 7745665Abstract: Disclosed herein are substituted phenethylamine alpha adrenergic receptor modulators of Formula I, process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.Type: GrantFiled: June 3, 2008Date of Patent: June 29, 2010Assignee: Auspex Pharmaceuticals, Inc.Inventors: Thomas G. Gant, Sepehr Sarshar
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Publication number: 20090130016Abstract: Provided is a thermionic cathode doped with an increased binding energy hydrogen species and a method of making the doped thermionic cathode.Type: ApplicationFiled: May 21, 2008Publication date: May 21, 2009Inventor: Randell L. Mills
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Publication number: 20080299217Abstract: The present application describes deuterium-enriched bifeprunox, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.Type: ApplicationFiled: June 1, 2007Publication date: December 4, 2008Applicant: PROTIA, LLCInventor: Anthony W. Czarnik
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Publication number: 20080299219Abstract: The present application describes deuterium-enriched oxybutynin, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.Type: ApplicationFiled: June 1, 2007Publication date: December 4, 2008Applicant: PROTIA, LLCInventor: Anthony W. Czarnik
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Publication number: 20080299216Abstract: The present application describes deuterium-enriched aripiprazole, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.Type: ApplicationFiled: June 1, 2007Publication date: December 4, 2008Applicant: PROTIA, LLCInventor: Anthony W. Czarnik
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Publication number: 20080299218Abstract: The present application describes deuterium-enriched valsartan, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.Type: ApplicationFiled: June 1, 2007Publication date: December 4, 2008Applicant: PROTIA, LLCInventor: Anthony W. Czarnik
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Publication number: 20080299215Abstract: The present application describes deuterium-enriched lestaurtinib, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.Type: ApplicationFiled: May 29, 2007Publication date: December 4, 2008Applicant: PROTIA, LLCInventor: Anthony W. Czarnik
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Publication number: 20080145303Abstract: [PROBLEMS] To provide a method for producing heavy hydrogen gas, which enables heavy hydrogen gas to be efficiently produced from a deuterated solvent as a reaction substrate. [MEANS FOR SOLVING PROBLEMS] (1) A method for producing heavy hydrogen gas, comprising bringing a deuterated solvent into contact with hydrogen gas under pressure in the coexistence with a catalyst selected from a palladium catalyst, a platinum catalyst, a nickel catalyst, a cobalt catalyst, an iridium catalyst, and a rhodium catalyst and a ruthenium catalyst which are not coordinated with a ligand, and (2) a catalytic deuteration method of a compound having a reducible functional group, comprising bringing the heavy hydrogen gas obtained by the above (1) into contact with the compound having a reducible functional group in the coexistence with a catalytic reduction catalyst.Type: ApplicationFiled: January 16, 2006Publication date: June 19, 2008Applicant: WAKO PURE CHEMICAL INDUSSRIES, LTD.Inventors: Kosaku Hirota, Hironao Sajiki, Nobuhiro Ito
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Patent number: 7153486Abstract: A method to catalyze hydrogen isotope exchange between water and hydrogen in which the water and hydrogen are contacted with a wetproofed catalyst, the catalyst having a hydrophobic porous matrix which has dispersed therein catalytically active platinum and at least one other metal which is chromium or titanium.Type: GrantFiled: September 28, 2004Date of Patent: December 26, 2006Assignees: Atomic Energy of Canada Limited, Energie Atomique Du Canada LimiteeInventors: Jintong Li, Sam Suppiah, Keith Kutchcoskie
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Patent number: 7033568Abstract: A palladium hydride superconductor, PdyHx where yHx is 1Hx, 2Hx, or 3Hx, having a critical temperature Tc?11K and stoichiometric ratio x?1. The critical temperature is proportional to a power of the stoichiometric ratio, which is stable over periods exceeding 24 hours, temperature variations from 4K to 400K, and pressures down to 1 mbar. The palladium hydride is coated with a stabilizing material such as a metal, metal oxide, ceramic, or polymer that can bond to palladium. It can be made by electrochemically loading a palladium lattice with isotopic hydrogen in an electrolytic solution, by allowing isotopic hydrogen to diffuse into a palladium thin film in a pressure chamber, or by injecting isotopic hydrogen into a palladium thin film in a vacuum chamber. The stabilizing material can be electrochemically bonded to the surface of the palladium hydride, or deposited using chemical vapor deposition or molecular beam epitaxy.Type: GrantFiled: March 12, 2001Date of Patent: April 25, 2006Inventor: Paolo Tripodi
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Patent number: 6221331Abstract: A synthetic route for forming lithium trisubstituted borohydride compounds comprises the step of reacting a processed lithium hydride reactant with a trisubstituted borane wherein the reaction is maintained for a period of time in a temperature range of approximately 15° C. to approximately 42° C. A method of synthesizing LiH comprises the step of reacting an alkyl lithium (for example, n-butyl lithium) with hydrogen in the presence of tetrahydrofuran. The reaction temperature is preferably maintained in the range of approximately −78° C. to approximately 25° C.Type: GrantFiled: January 24, 2000Date of Patent: April 24, 2001Assignee: Mine Safety Appliances CompanyInventors: Elizabeth R. Burkhardt, Christopher P. Sutton, Joerg Bruening, David F. Rouda