Extract Or Material Containing Or Obtained From A Unicellular Fungus As Active Ingredient (e.g., Yeast, Etc.) Patents (Class 424/195.16)
  • Patent number: 7172888
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with lung cancer. The biological compositions can be used to retard the growth of lung cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Grant
    Filed: September 13, 2005
    Date of Patent: February 6, 2007
    Assignee: Ultra Biotech Limited
    Inventor: Ling Yuk Cheung
  • Patent number: 7163813
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with colorectal cancer. The biological compositions can be used to retard the growth of colorectal cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Grant
    Filed: September 13, 2005
    Date of Patent: January 16, 2007
    Assignee: Ultra Biotech Limited
    Inventor: Ling Yuk Cheung
  • Patent number: 7147860
    Abstract: Present invention relates to a method and composition for symptomatic relief of vaginitis. Until the treatment of underlying cause takes effect women suffer from unpleasant symptoms of vaginitis restricting daily routine activities. The symptoms of vaginitis may be incapacitating and are a common reason for visiting the gynecologist and can lead to frustration, embarrassment, anger, lost days from work, marital conflict and loss of ability to enjoy a normal personal, professional and social life.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: December 12, 2006
    Assignee: Centum Research, LLC
    Inventor: Syed Ritzi
  • Patent number: 7074437
    Abstract: The increased level of glucose in blood is the result of the destruction of ? cells of the Islets of Langerhans by autoimmune process in insulin-dependent form of diabetes or a relative lack of insulin in insulin-dependent form of diabetes. Constantly present hyperglycemia in diabetes and a relative lack of insulin aid the development of the neuropathy as a late complication of diabetes. For that purpose, a technical problem was set before the inventor with the request of the reduction of glucose in blood, and stopping of the process of the development of the neuropathy as the consequence of the “long” duration of diabetes. Such a mineral-protein preparation was prepared by which glycemia was successfully regulated, but the process was also stopped by depositing of Ca+ in nerve cells. Those early changes caused by diabetes were successfully stopped, so that the appearance of the neuropathy, as a late complication in diabetes, was postponed.
    Type: Grant
    Filed: July 5, 2002
    Date of Patent: July 11, 2006
    Inventors: Robert Basic, Mirko Hadzija, Boris Subotic
  • Patent number: 7060286
    Abstract: The present invention provides an external preparation for skin which contains, as a major ingredient, oleaginous substances extracted from sporoderm-broken spores from Ganoderma lucidum. The spores are preferably being treated with germination activation. The oleaginous substances are preferred to be extracted by a supercritical fluid-carbon dioxide (SCF-CO2) method. The oleaginous substances prepared by SCF-CO2 is transparent and odorless. They also demonstrates effects on skin smoothening, wrinkles reduction, aging defiance, inflammation lessening, pigmentation lightening, and irritation alleviation. The external preparation can be a cosmetic or a therapeutic composition.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: June 13, 2006
    Inventors: Chee-Keung Chung, Siu-Kan Tong
  • Patent number: 7048933
    Abstract: Remedies for allergic diseases obtained by mixing shoots of plants belonging to the family Pinaceae with water and saccharides followed by spontaneous fermentation. As the plants belonging to the family Pinaceae, is preferable to use plants belonging to the genus Pinus. These remedies, which enable complete recovery in a short administration time without showing any side effects, are useful as remedies for allergic diseases, in particular, asthma and atopic dermatitis. Also, a yeast isolated from these remedies for allergic diseases is provided.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: May 23, 2006
    Assignee: Koji Fukuda
    Inventor: Harui Fukuda
  • Patent number: 6989253
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with testicular cancer. The biological compositions can be used to retard the growth of testicular cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: January 24, 2006
    Assignee: Ultra Biotech Limited
    Inventor: Ling Yuk Cheung
  • Patent number: 6987012
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with colorectal cancer. The biological compositions can be used to retard the growth of colorectal cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: January 17, 2006
    Assignee: Ultra Biotech Limited
    Inventor: Ling Yuk Cheung
  • Patent number: 6984508
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with cervical cancer. The biological compositions can be used to retard the growth of cervical cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: January 10, 2006
    Assignee: Ultra Biotech Limited
    Inventor: Ling Yuk Cheung
  • Patent number: 6984507
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with lung cancer. The biological compositions can be used to retard the growth of lung cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Grant
    Filed: June 11, 2003
    Date of Patent: January 10, 2006
    Assignee: Ultra Biotech Limited
    Inventor: Ling Yuk Cheung
  • Patent number: 6972284
    Abstract: A highly deacetylated chitosan obtained from microbial biomass, a method of obtaining chitosan from microbial biomass, and biomass for making chitosan are disclosed. The method includes providing chitin-containing biomass; reacting the chitin-containing biomass in a caustic solution of greater than 25 percent alkali at a reaction temperature greater than 95° C. for a reaction period of at least 10 hours to convert the chitin in the biomass to chitosan; and separating the chitosan from the caustic solution.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: December 6, 2005
    Assignee: Cargill, Incorporated
    Inventors: Weiyu Fan, John A. Bohlmann, James R. Trinkle, James Donald Steinke, Ki-Oh Hwang, Joseph P. Henning
  • Patent number: 6942860
    Abstract: The present invention is directed to a method for producing a new nematocidal composition particularly useful against plant parasitic nematodes and also a process to prevent damage resulting from nematode infestation. The method for production of the composition involves heating a pH-adjusted fermentation broth of microorganisms to a temperature of at least about 100° C. for at least about 15 minutes. Preferably, the microorganism is Gibberella fujikuroi, Streptomyces erythraeus, Bacillus sphaericus, Bacillus thuringiensis or Fusarium moniliforme.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: September 13, 2005
    Assignee: Valent BioSciences Corporation
    Inventors: Prem Warrior, Daniel Feulner Heiman, Linda Anne Rehberger, Ronald Eugene Johnson, James Russell Hansen, Kevin Allen McVicker
  • Patent number: 6919082
    Abstract: The present invention provides a pharmacological composition as a composition as a raw material capable of preventing or treating the symptoms of inflammatory bowel diseases such as ulcerative colitis, constipation, allergic diseases such as atopic dermatitis, and so on, and which has little side effect and thereby safe, high water dispersibility, and can be ingested easily. A yeast cell wall fraction, which comprises yeast extracts residue and being superior in water dispersibility and swelling properties, is used as an active constituent. As a yeast cell wall fraction, a yeast cell wall fraction obtained with a simple operation of water cleansing of yeast cell after alkali processing yields superior effects for preventing or treating the symptoms of inflammatory bowel diseases such as ulcerative colitis, constipation, allergic diseases such as atopic dermatitis, and so on, as well as such yeast cell wall fraction without foreign taste and odor characteristic to autolysis and suitable for ingestion.
    Type: Grant
    Filed: October 10, 2002
    Date of Patent: July 19, 2005
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Yoshiharu Shirasu, Tomohiko Nakamura, Hideyuki Wakabayashi
  • Patent number: 6858212
    Abstract: Provided is a process of and product resulting from adding a sub-lethal amount of a peroxide, or said peroxide in combination with sub-lethal ultra violet radiation, to a growing culture of a yeast; observing the change in absorbance of the culture at 256 nm as a measure of the injury occurring to the yeast cells, and upon reaching a predetermined absorbance value, purifying the water-soluble yeast extract from the peroxide containing yeast culture. The resulting product has at least 1.5 respiratory units per mg dry weight and has significantly increased amounts of 15, 25 and 55 kilo Daltons (kD) molecular weight products compared to a Live Yeast Cell Derivative as determined by SDS slab gel electrophoresis. This product can be combined with a cosmetically acceptable carrier to provide a composition suitable for topical application to the skin.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: February 22, 2005
    Assignee: Arch Personal Care Products, L.P.
    Inventors: Durant B. Scholz, Derek Parish, Hans Schaeffer
  • Patent number: 6858214
    Abstract: The invention relates to the use of nanoscalar water-soluble ?-(1,3) glucans, which are essentially free from ?-(1,6) links and have particle diameters ranging from 10 to 300 nm for producing cosmetic and/or pharmaceutical preparations. When applied topically, the especially fine dispersion of the particles, compared to prior art glucans, facilitates their rapid penetration of both the stratum corneum of the skin and the keratin fibres of the hair.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: February 22, 2005
    Assignee: Biotec ASA
    Inventors: Christian Kropf, Ute Griesbach, Bernd Fabry, Rolf E. Engstad
  • Publication number: 20040266726
    Abstract: To provide an anticancer composition. More specifically, the anticancer composition according to the present invention was successfully provided by newly finding the fact that a composition comprising a marine yeast-derived ingredient having &bgr;1,3 glucan structure is an unprecedentedly effective IL-12 inducer and further newly discovering that the composition can hold promise of NK and NKT cell activating capabilities as a result of oral administration of a marine yeast-derived ingredient having &bgr;1,3 glucan structure.
    Type: Application
    Filed: May 5, 2004
    Publication date: December 30, 2004
    Inventor: Akikuni Yagita
  • Publication number: 20040253266
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with esophageal cancer. The biological compositions can be used to retard the growth of esophageal cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253258
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with testicular cancer. The biological compositions can be used to retard the growth of testicular cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253252
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with leukemia. The biological compositions can be used to reduce the number of leukemia cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253255
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with nasopharyngeal cancer. The biological compositions can be used to retard the growth of nasopharyngeal cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253264
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with brain cancer. The biological compositions can be used to retard the growth of brain cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253265
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with bladder cancer. The biological compositions can be used to retard the growth of bladder cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253254
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with lung cancer. The biological compositions can be used to retard the growth of lung cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253267
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with breast cancer. The biological compositions can be used to retard the growth of breast cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253268
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with uterine cancer. The biological compositions can be used to retard the growth of uterine cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253262
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with lymphoma. The biological compositions can be used to retard the growth of lymphoma cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253251
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with ovarian cancer. The biological compositions can be used to retard the growth of ovarian cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253256
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with prostate cancer. The biological compositions can be used to retard the growth of prostate cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253257
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with liver cancer. The biological compositions can be used to retard the growth of liver cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253260
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with cervical cancer. The biological compositions can be used to retard the growth of cervical cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253253
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with stomach cancer. The biological compositions can be used to retard the growth of stomach cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253263
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with colorectal cancer. The biological compositions can be used to retard the growth of colorectal cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253259
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with kidney cancer. The biological compositions can be used to retard the growth of kidney cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040253261
    Abstract: The present invention relates to pharmaceutical compositions and dietary supplement comprising yeast cells that can produce a healthful benefit in a subject inflicted with pancreatic cancer. The biological compositions can be used to retard the growth of pancreatic cancer cells and/or prolonging the time of survival of the subject. The invention also relates to methods for manufacturing the biological compositions.
    Type: Application
    Filed: June 11, 2003
    Publication date: December 16, 2004
    Inventor: Ling Yuk Cheung
  • Publication number: 20040247619
    Abstract: A therapeutic herbal composition comprising Saw Palmetto, Bromelain, Willow Herb, Grape Seed Complex, Wild Rosella, Liquorice, Passionfruit Seed and Selenium Yeast is claimed. The composition may be used as a general health promotant but is also useful as a treatment of cancer and inflammation. Prostrate cancer and hyperplasia may be particularly beneficially addressed with the composition. The invention extends to a method of treatment using a composition as described.
    Type: Application
    Filed: July 27, 2004
    Publication date: December 9, 2004
    Inventor: Joanne Hambrook
  • Publication number: 20040247559
    Abstract: A cosmetic material which not only inhibits tyrosinase activity and melanin production but also erases free radicals and activates cells, thereby reliably maintaining white skin. The cosmetic material contains as its active ingredient an extract in aqueous solvent of a yeast of the genus Schizosaccharomyces such as Schizosaccharomyces pombe by 0.05-10 wt %.
    Type: Application
    Filed: June 9, 2004
    Publication date: December 9, 2004
    Inventors: Tanaka Katsumasa, Nagai Tsutomu
  • Publication number: 20040234630
    Abstract: The use of a food portion comprising dry and/or wet distiller's grain for preventing, treating or ameliorating cardiovascular pathologies is described.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 25, 2004
    Inventor: Rajat Sethi
  • Publication number: 20040234545
    Abstract: A therapeutic agent for treating diseases caused by retroviruses is provided. The agent acts by inducing secretion of biological anti-microbial peptides. Specifically, the therapeutic agent is intended to treat retroviral infections and contains as an active ingredient fermentation products produced by yeasts and lactic acid bacteria. Among the diseases caused by retrovirus that can be treated with the therapeutic agent are acquired immune deficiency syndrome (AIDS) and adult T-cell leukemia (ATL) caused by human T-cell lymphotropic virus-I (HTLV-I).
    Type: Application
    Filed: June 29, 2004
    Publication date: November 25, 2004
    Inventor: Hisashi Fujimura
  • Patent number: 6790464
    Abstract: Methods and compositions are disclosed for prevention or treatment of prostate disorders and ameliorating symptoms thereof, including prostatitis, benign prostate hyperplasia and prostatic carcinoma.
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: September 14, 2004
    Assignee: Healthaid Enterprise Pte. Ltd.
    Inventors: Koon Yong Kuok, Hien Ly
  • Publication number: 20040156858
    Abstract: Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.
    Type: Application
    Filed: December 16, 2003
    Publication date: August 12, 2004
    Inventors: Alex Franzusoff, Donald Bellgrau
  • Publication number: 20040151738
    Abstract: A dietetic product belonging to the family of food products, complements or supplements for slimming or anti-obesity and appetite suppressing or satiating food products, complements or supplements containing an efficient dose of food proteins, 70% of which at least are hydrolysed yeast proteins. The invention also concerns the use of the dietetic product in an aesthetic slimming diet. The invention further concerns the use of hydrolysed yeast proteins in the preparation of such a dietetic product.
    Type: Application
    Filed: November 19, 2003
    Publication date: August 5, 2004
    Inventors: Eric Oriol, Gilles Fromentin
  • Publication number: 20040147028
    Abstract: A liposome for fusing with a yeast cell, the liposome characterised in that about 40-50 molar % of the liposome lipid bilayer is phosphatidyl choline (PC), about 10-20 molar % of the liposome lipid bilayer is a cationic amphiphile, about 10 molar % of the liposome lipid bilayer is a sterol and about 30 molar % of the liposome lipid bilayer is phosphatidyl ethanolamine (PE) and/or dioleoylphosphatidylethanolamine (DOPE).
    Type: Application
    Filed: December 11, 2003
    Publication date: July 29, 2004
    Inventor: Michael Patane
  • Patent number: 6750048
    Abstract: The present invention provides a method for extracting lipids from microorganisms without using organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microorganisms by lysing cells and removing water soluble compound and/or materials by washing the lysed cell mixtures with aqueous washing solutions until a substantially non-emulsified lipid is obtained.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: June 15, 2004
    Assignee: Martek Biosciences Corporation
    Inventors: Craig M. Ruecker, Swithin Patrick Adu-peasah, Brian S. Engelhardt, George T. Veeder, III
  • Publication number: 20040109872
    Abstract: Therapeutic compositions and methods for using same for treating skin conditions and diseases are disclosed. Treatable skin conditions and diseases include without limitation acne vulgaris, rosacea, seborrheic dermatitis, eczema (atopic dermatitis), psoriasis, photo-aging and actinic keratosisacne vulgaris, psoriasis, photo-aging and eczema. Therapeutic compositions disclosed are derived from Porifera species, specifically sponges, and more specifically fresh water sponges. One disclosed embodiment is derived from Spongilla species and is formulated with pharmaceutically acceptable excipients.
    Type: Application
    Filed: September 9, 2003
    Publication date: June 10, 2004
    Inventor: Maria Villani
  • Publication number: 20040105870
    Abstract: Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is observed in patients who seldom or never consume alcohol. Nonalcoholic steatohepatitis can lead to serious liver damage, and ultimately cirrhosis. The present invention provides methods and compositions useful for the treatment or alleviation of nonalcoholic steatohepatitis and the pharmaceutical formulations for their administration to a human. Specifically, compositions comprised of lecithin, antioxidants and vitamin B complex are administered parenterally, most preferably by oral administration. Specific therapeutic formulations include admixtures of these compounds and specific dosage formulations include daily oral administrations of these compounds in tablet or powder forms.
    Type: Application
    Filed: November 13, 2003
    Publication date: June 3, 2004
    Inventors: Houn Simon Hsia, David Fan
  • Publication number: 20040101515
    Abstract: Disclosed are gel-based cosmetic and wound-healing formulations, methods for making said formulations, and a method for simultaneously treating and concealing injuries to human skin. In one exemplary embodiment, the cosmetic and wound-healing formulation comprises live yeast cell extract, pigment, and a gel.
    Type: Application
    Filed: May 19, 2003
    Publication date: May 27, 2004
    Inventors: Barry Knapp, Ronald DiSalvo
  • Publication number: 20040096485
    Abstract: Disclosed are methods and products such as wet wipes and absorbents capable of providing a skin health benefit when utilized in the intended fashion. More specifically, the products described herein comprise an agent, such as a botanical extract, which is capable of increasing the activity of sphingomyelinase according to a Sphingomyelinase Activity Screening Test and/or decreasing the activity of ceramidase according to a Ceramidase Activity Screening Test. By increasing the activity of sphingomyelinase and/or decreasing the activity of ceramidase, the agents in combination with the products described herein are able to maintain or increase the level of ceramides in the skin leading to improved skin health.
    Type: Application
    Filed: November 19, 2002
    Publication date: May 20, 2004
    Applicant: Kimberly-Clark Worldwide, Inc.
    Inventors: David W. Koenig, Jamie Joseph Van Gompel
  • Patent number: 6733793
    Abstract: An orally administered, novel dietary supplement or therapeutic composition capable of insulin-like activity in animals, preferably humans, is provided. Contained in the composition are therapeutically effective amounts of vanadyl sulfate, alpha-lipoic acid, taurine, and chromium carnitine. The composition is preferably orally administered on a daily basis for at least about 4 weeks and can be used by normal, healthy individuals as well as diabetics.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: May 11, 2004
    Assignee: MetaProteomics, LLC
    Inventors: Linda M. Pacioretty, John G. Babish
  • Publication number: 20040086526
    Abstract: The invention relates to a process for the production of preparations for stimulating human skin cells and for protection against aging of the skin and the harmful effects of environmental toxins and UV radiation, characterized in that the preparations contain at least one substance which increases the synthesis of energy donors of the mitochondrial respiratory chain and, at the same time, lowers the level of reactive oxygen species (ROS) in the cell metabolism. The invention also relates to the use of cosmetic and/or pharmaceutical preparations containing at least one substance which increases the synthesis of energy donors of the mitochondrial respiratory chain and, at the same time, lowers the level of reactive oxygen species (ROS) in the cell metabolism for stimulating human skin cells and for protection against aging of the skin and against the harmful effects of environmental toxins and UV radiation.
    Type: Application
    Filed: July 16, 2003
    Publication date: May 6, 2004
    Inventors: Louis Danoux, Olga Freis, Gilles Pauly
  • Publication number: 20040081663
    Abstract: A composition for treatment and prevention of cancer including a Monascus fermentation extract as active component. The inventive Monascus extract is produced by liquid fermentation, and includes at least one component with three characteristic ultraviolet absorption peaks at 230, 237 and 246 nm.
    Type: Application
    Filed: May 23, 2003
    Publication date: April 29, 2004
    Inventors: Chun-Min Chang, Ming-Da Hu, Chien-Yang Li, Chih-Chung Yeh