Abstract: A method of treating a disorder in an eye, for example, an aqueous deficient dry eye state, phacoanaphylactic endophthalmitis, or uveitis, is provided. The method generally includes administering a therapeutically effective amount of a certain cyclosporin A derivative topically to the affected eye. The derivative may be administered as a solution, suspension or ointment in a pharmaceutically acceptable excipient.

Abstract: A form of administration for applying pharmaceutical substances, auxiliary substances and diagnostic agents including a flexible carrier which is water repellant or is rendered water repellant, having a preparation in the form of a lyophilizate adhering to the carrier. The preparation contains a medicament and a hydrophilic polymer which can swell or is water-soluble. During application, the preparation is detached from the carrier for the purpose of application by rehydration of the preparation on contact with liquid.

Abstract: Pharmaceutical preparations are described, comprised of salts of hyaluronic acid with a basic anesthetic containing aliphatics and/or amino groups, particularly salts with benzydamine or bupivacaine.

Abstract: An ophthalmic composition for prophylaxis and/or treatment of keratoconjunctivitis sicca, which is locally administered to the eyes and which comprises, as an effective component, at least one member selected from the group consisting of vitamin D, active vitamin D, and active vitamin D analogues.

Abstract: In vivo polymerizable intraocular lens compositions which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the unsaturated fluorophobic ends. The compositions are preferably cured by UV photoinitiation and are useful in repairing torn or detached retinal tissue or forming intraocular lenses in situ.

Abstract: The present invention is directed to a lubricant for contact lenses or dry eye or to provide relief from eye irritation. In particular, the composition contains a biguanide preservative in combination with polyvinylpyrollidone. An ophthalmic solution containing such a combination of components can be applied, in the form of droplets, to the eye or to contact lens in the eye. In one embodiment of the invention, the composition is used as a universal lubricant, meaning that the same solution can be used with or without contact lenses, depending on the needs of the user, whether in the context of a contact-lens care or general eye care.

Abstract: An agent for contact lenses, which comprises an aqueous medium and synthetic smectites particulates consisting essentially of primary particles having a particle size of at most 200 nm, dispersed in the aqueous medium.

Abstract: Ophthalmic drug delivery vehicles which are administrable as a liquid and which gel upon contact with the eyes are disclosed. The vehicles contain xanthan gum.

Abstract: A process for the preparation of biologically active silicon compounds by hydrolysis of a precursor which produces a compound which prevents the formation of polymers from the silicon hydrolyzed bonds.