Viral Vaccine For Equine Species (e.g., Horses, Etc.) Patents (Class 424/820)
  • Use of bacterium for manufacture of a vaccine
    Patent number: 8084040
    Abstract: The present invention relates to the use of live attenuated bacteria for the manufacture of a vaccine for submucosal administration.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: December 27, 2011
    Assignee: Intervet International B.V.
    Inventors: Antonius Arnoldus Christiaan Jacobs, Daniel G. E. Goovaerts
  • EIA vaccine and diagnostic
    Patent number: 6585978
    Abstract: The invention provides an equine infectious anemia (EIA) vaccine that provides immunity to mammals, especially equines, from infection with equine infectious anemia virus (EIAV) and which allows differentiation between vaccinated and non-vaccinated, but exposed, mammals or equines. Preferably said vaccine encompasses at least one mutation in an EIAV which produces a non-functional gene in the vaccine virus that is always expressed in disease-producing wild-type EIA viruses. Additionally, said EIA vaccine virus cannot cause clinical disease in mammals or spread or shed to other mammals including equines.
    Type: Grant
    Filed: September 9, 2000
    Date of Patent: July 1, 2003
    Assignee: Akzo Nobel
    Inventors: Ronald Montelaro, Bridget Puffer, Feng Li, Charles Issel, Kristina J. Hennessy, Karen K. Brown
  • Live attenuated Venezuelan Equire encephalitis vaccine
    Patent number: 6296854
    Abstract: A live attenuated Venezuelan equine encephalitis virus (VEE) is described which comprises a viral gene rearrangement. This rearranged attenuated virus is useful as vaccine for protection against infection with VEE. Methods of preparing the virus and methods of using the virus are described.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: October 2, 2001
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Peter Pushko, Michael D. Parker, Jonathan F. Smith, Bruce J. Crise
  • Equine herpesvirus-4TK mutant
    Patent number: 6025181
    Abstract: An Equine herpesvirus-4 (EHV-4) mutant which does not produce a functional thymidine kinase due to a deletion and/or insertion in the gene encoding thymidine kinase, the deletion and/or insertion made at a position within the thymidine kinase gene such as to not substantially alter expression of the UL24 gene. Recombinant DNA comprising DNA of the EHV-4 mutant, host cells containing the recombinant DNA, and a process for the preparation of the EHV-4 mutant.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: February 15, 2000
    Assignees: University Court of the University of Glasgow, Equine Virology Research Foundation
    Inventors: David Edward Onions, Lesley Nicolson