Treatment Of Live Animal Patents (Class 426/2)
  • Patent number: 12290084
    Abstract: A composition for improving intestinal beneficial bacteria in companion animals, includes barley sprout extract powder, broccoli sprout extract powder, omega-3 fatty acid, zeolite powder, arginine powder, glutathione powder, chlorella powder, green leaf mussel extract powder, brown rice (unpolished rice) enzyme powder, Kamut enzyme powder, plantago seed (psyllium) husk powder, Clostridium butyricum strain Miyairi, N-acetylglucosamine, epigallocatechin-3-gallate and croscarmellose sodium, as active ingredients, and may promote the activation of intestinal beneficial bacteria through edible feeding, thereby contributing to health improvement.
    Type: Grant
    Filed: October 31, 2024
    Date of Patent: May 6, 2025
    Inventor: Tae Yoon Kim
  • Patent number: 12285454
    Abstract: The present invention discloses an anti-aging Chinese herb extract, an extraction method and a use thereof. The ginseng-Astragalus membranaceus extract of the present invention comprises 20 to 30% of astragaloside, 1 to 5% of ginsenoside Rg1, 2 to 6% of ginsenoside Re, 0.2 to 0.5% of ginsenoside Rb1. There are 17 characteristic peaks in high-performance liquid chromatography fingerprints of the extract. The extract can effectively improve activity of telomerase, delay cell aging, and can be applied to preparation of an anti-aging product.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: April 29, 2025
    Assignee: HEALTH LIFE BIOSCIENCES INC
    Inventors: Jin Chen, Yunyan He, Jun Su, Ai Li
  • Patent number: 12280040
    Abstract: Ectoparasite infestations in fish farming can pose significant challenges and issues for aquaculture operations. This disclosure generally relates to treatment or control of ectoparasite infestations (such as sea lice infestations) on fish (such as salmonids) using a particular dosing regimen of an isoxazoline. In particular, the dosing regimen includes oral administration of the active ingredient: (S)-3-methyl-N-(2-oxo-2-(prop-2-yn-1-ylamino) ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl) thiophene-2-carboxamide, including salts, or N-oxide, or solvates thereof, of structural formula The active ingredient may be administered at a dosage (i.e., in a dose) of from about 0.025 mg/kg/d to about 0.250 mg/kg/d. The dosing regimen may include oral administration from about 3 to about 10 consecutive days.
    Type: Grant
    Filed: September 13, 2024
    Date of Patent: April 22, 2025
    Assignee: EVAH Atlantic Inc.
    Inventor: Lisa Michele Phillips
  • Patent number: 12187672
    Abstract: Disclosed are a novel 1,2-diacylglycerol compound that useful for improving, preventing or treating inflammation-related diseases by inhibiting overexpression of various inflammatory cytokines such as IL-4 and IL-6 or chemokine CXCL8 related to the migration of inflammatory cells, a method for preparing the same, and an immunomodulator containing the same as an active ingredient. The 1,2-diacylglycerol compound is represented by Chemical Formula 2 in the patent specification.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: January 7, 2025
    Assignee: ENZYCHEM LIFESCIENCES CORPORATION
    Inventors: Ki Young Sohn, Jae Wha Kim, Sun Young Yoon, Chang Hyun Yoo, Jin Seon Jeong
  • Patent number: 12178226
    Abstract: Showb here is a process for preparing a concentrated liquid composition (such as a broth) from poultry or other meat sources without the use of any enzymes. The resultant composition may have high content of solids but are pumpable or pourable and have relatively long shelf life at room temperature. Also shown are methods of extracting proteins from raw poultry or other meat sources at relatively low temperatures. Methods of making a high protein curd is also shown.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: December 31, 2024
    Assignee: INTERNATIONAL DEHYDRATED FOODS, INC.
    Inventors: Roger Lynn Dake, Nancy Lewis
  • Patent number: 12178228
    Abstract: A thickening powder promotes safe swallowing of a composition by an individual with dysphagia and can be used in methods of treating dysphagia, promoting safe swallowing of a composition, and mitigating a risk of aspiration during swallowing of a composition. The powder contains beta-glucan and maltodextrin in an amount that is neutral toward or enhances the extensional properties of the composition. Optionally the thickening powder can also include a low molecular weight carbohydrate such as sucrose or lactose. The powder can be diluted in a liquid comprising at least one of water or milk to form at least a portion of a composition such as a nutritional product and to improve the cohesiveness of the composition.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: December 31, 2024
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Giulia Marchesini, Jan Engmann, Christoph Widmer, Thibaut Dutter
  • Patent number: 12167738
    Abstract: The present invention relates to a method for providing an individualized nutritionally complete diet for an animal, in particular an animal with one or more pathological condition(s). The present invention also relates to a device for providing an individualized nutritionally complete diet for an animal, having means adapted to execute the steps of the method. The present invention also relates to a computer program to cause the device to execute the steps of the method. A computer-readable medium having stored thereon the computer program is further provided. Kits and compositions are further provided.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: December 17, 2024
    Assignee: MARS, INCORPORATED
    Inventors: Jean-Baptiste Roche, Claude Ecochard, Sally Perea
  • Patent number: 12161615
    Abstract: The invention provides a food supplement comprising chromium and the five amino acids leucine, isoleucine, valine, threonine and lysine, wherein leucine, isoleucine, valine, threonine and lysine are the only amino acids present in the food supplement, and wherein the sum content of the five amino acids is from 1.75 to 3.5 g per dose of the food supplement, and wherein the content of chromium is from 4.5 to 61 ?g per dose of the food supplement. A food composition comprising the food supplement, as well as the five amino acids for use in a method of treating, controlling or preventing diseases or conditions related to the metabolic syndrome, treating or controlling diabetes, treating, controlling or preventing obesity, promoting satiety, promoting weight loss, or promoting maintenance of a healthy bodyweight, by lowering postprandial glycaemia, and preferably also by lowering postprandial insulin secretion, are also provided.
    Type: Grant
    Filed: June 22, 2023
    Date of Patent: December 10, 2024
    Assignee: DOUBLEGOOD AB
    Inventors: Rickard Öste, Elin Östman, Inger Björck
  • Patent number: 12163966
    Abstract: A method is provided, comprising feeding a cat a foodstuff comprising a protein to fat ratio of 1:0.27 to 1:0.63 on a gram:gram as fed or dry matter basis, and measuring the level of glucose-dependent insulinotropic polypeptide (GIP) in a blood sample from the cat before and after feeding the foodstuff. A reduction in GIP levels and/or maintaining low levels of GIP post-prandially is indicative of a foodstuff useful in preventing accumulation of and/or reducing body fat in a cat and therefore controlling the body weight of a cat.
    Type: Grant
    Filed: November 25, 2019
    Date of Patent: December 10, 2024
    Assignee: Mars, Incorporated
    Inventors: Janet Alexander, Penelope Morris, Adrian Hewson-Hughes
  • Patent number: 12108776
    Abstract: The present invention is related to feed granules comprising a feed enzyme and a zinc salt of an organic acid.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: October 8, 2024
    Assignee: Novozymes A/S
    Inventors: Erik Marcussen, Poul Erik Jensen
  • Patent number: 12111302
    Abstract: A diagnostic assay to determine a percentage rumen undegraded protein in a food product by comparing the percentage of modified protein content to the total crude protein content of the food product. The total crude protein content extracted from a food product sample prior to conducting gel electrophoresis to separate modified protein content from the total crude protein content. The gel band intensities of the separated protein contents analyzed to enumerate a ratio that is used to derive a correlated percentage numen undegraded protein for a given food product sample. The diagnostic assay capable of being provided onsite for quick, cost-efficient and accurate results.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: October 8, 2024
    Assignee: Novita Nutrition, LLC
    Inventors: Keith E. Bruinsma, Donald L. Endres, Andrew James Manning, Kurt M. Swenson
  • Patent number: 12091623
    Abstract: A fuel additive composition comprising an anthocyanidin; an amino acid; and a catalyst. The anthocyanidin may comprise delphinidin chloride. The amino acid may comprise aspartic acid, leucine acid, glutamic acid, a non-natural amino acid, or a combination thereof. Embodiments of the present invention also relate to a method for making of fuel additive, the method comprising: providing an anthocyanidin; contacting the anthocyanidin with an amino acid to form an anthocyanidin-amino acid mixture; contacting the anthocyanidin-amino acid mixture with a catalyst. The method may further comprise contacting the anthocyanidin-amino acid mixture with ethanol and/or an acid. The method may further comprise adjusting the pH of the anthocyanidin-amino acid mixture to less than 7.
    Type: Grant
    Filed: September 29, 2023
    Date of Patent: September 17, 2024
    Inventor: Clifton Ray Taylor
  • Patent number: 12070480
    Abstract: The invention relates to various compositions for improving exercise performance and/or recovery. The invention also relates to methods of using these compositions and kits including these compositions to improve exercise performance and/or recovery.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: August 27, 2024
    Assignee: Beachbody, LLC
    Inventors: Nima Alamdari, Michael Wilson, May Lam
  • Patent number: 12070048
    Abstract: A method of producing a hybrid foodstuff is provided. The method comprises combining a plant-originated substance with an amount of cultured animal cells so as to enhance a meat organoleptic and/or meat nutritional property in the hybrid foodstuff, wherein the animal cells do not form a tissue, and wherein the amount is below 30% (w/w) of the hybrid foodstuff.
    Type: Grant
    Filed: December 14, 2022
    Date of Patent: August 27, 2024
    Assignee: SuperMeat the Essence of Meat Ltd.
    Inventors: Ido Savir, Shir Friedman, Koby Barak
  • Patent number: 11926855
    Abstract: An enzyme composition containing a protease combination or a protease mixture having neutral metalloprotease and serine alkaline protease activity, and an amylase. Feed compositions, additives and formulations containing the enzyme composition in methods for improving digestibility of proteins in an animal diet or animal feed, as well as optimizing the nutritional value of an animal diet or animal feed.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: March 12, 2024
    Assignee: Kerry Group Services International Limited
    Inventors: Niall Higgins, Jacques Georis, Sara Llamas Moya, Nathan Marshall, Derek Carr, Rachel Maloney, Laura Guaras
  • Patent number: 11819040
    Abstract: Methods for providing dietary calcium to livestock and other animals and the compositions for use in providing dietary calcium to livestock are disclosed. Kits to provide the animal with a desired amount of supplemental calcium during normal watering is also disclosed.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: November 21, 2023
    Assignee: DSM IP ASSETS B.V.
    Inventors: Aaron Cowiesen, Jose-Otavio Sorbara
  • Patent number: 11801272
    Abstract: The present invention relates to Bacillus strains which improves health and performance of production animals. The invention further relates to compositions comprising the Bacillus strains.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: October 31, 2023
    Assignee: Novozymes A/S
    Inventors: Derrick Lewis, Marianne Thorup Cohn, Adam Nelson, Preben Nielsen
  • Patent number: 11802834
    Abstract: Various embodiments disclosed relate to methods of predicting neutral detergent fiber digestibility (NDFD) properties of a feedstuff sample. A method of predicting neutral detergent fiber digestibility (NDFD) properties of a feedstuff sample includes collecting a near-infrared spectrum of the feedstuff sample to provide NIR data of the feedstuff sample. The method also includes predicting NDFD of the sample at an elapsed time, NDFD rate of the sample, and/or NDFD extent of the sample from the NIR data using a NIR/NDFD calibration model. Various embodiments provide a method of developing the NIR/NDFD calibration model using in vitro gas production (IVGP). Various embodiments provide a method of predicting digestibility of the feedstuff sample for an animal at a rumen passage rate (eNDF).
    Type: Grant
    Filed: October 27, 2021
    Date of Patent: October 31, 2023
    Assignee: CAN TECHNOLOGIES, INC.
    Inventors: Kelly Curran Koski, Gladys Ethel Margaria, Pam Paumen, Kathryn L. Plaisance, Vivian Adele Schouten, Guillermo Fernando Schroeder, Paul R. Score, Yan Sun
  • Patent number: 11780876
    Abstract: A method of preparing a complete protein by the addition of essential amino acids to an incomplete protein can include calculating an amount of each essential amino acid to be added to an incomplete protein and adding the calculated amount of each essential amino acid to the incomplete protein. The calculations can be done using a particular equation, described herein.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: October 10, 2023
    Inventor: Arthur Merrill Zemach
  • Patent number: 11638433
    Abstract: A process for extraction of crude oil from distillers dried grain solubles and/or distillers dried grains using a solvent extraction process and producing corn distillers meal that may be used as an animal feed supplement is disclosed. The corn distillers meal may be used as a crude protein supplement for use in a livestock feed diet, poultry feed diet, aquatic feed diet or the like. The solvent extracted crude oil may be suitable for other processes, including oleochemical processing for personal care and home care products, biodiesel production, and/or renewable diesel production from hydro-treating the extracted oil to make green diesel fuel.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: May 2, 2023
    Assignee: Novita Nutrition, LLC
    Inventors: Keith Bruinsma, Donald Endres, Steven J. Furcich
  • Patent number: 11627749
    Abstract: Disclosed embodiments concern a composition and/or combination, and a method of administering the same as a feed, or to supplement the feed of, aquatic animals, particularly for aquaculture. Disclosed composition and/or combination embodiments may comprise glucan, silica, mineral clay, mannans, yucca, quillaja, a probiotic, and/or an adhesive agent. The adhesive agent may be selected particularly to facilitate administration to aquatic species. In certain embodiments the adhesive agent comprises an oil, such as soy oil, or a syrup, such as molasses, or combinations thereof. In some embodiments the composition and/or combination may further comprise polyphenol, an antimicrobial, and/or a vaccine. Also disclosed is a method for promoting growth and/or immune function in aquatic animals.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: April 18, 2023
    Assignee: Omnigen Research, LLC
    Inventors: Ra'anan Ariav, Neil E. Forsberg, Steven B. Puntenney
  • Patent number: 11606960
    Abstract: A pet food containing naturally occurring copper that can be used as a prophylactic diet to prevent and/or reduce copper storage disease, dilated cardiomyopathy, adverse gastrointestinal food reactions, and/or food allergies in pets is provided. A method for forming this pet food containing naturally occurring copper includes: providing a formula selected from the group consisting of chicken meal, corn gluten, duck, rabbit, venison, fish, peas, potato, barley, rice, corn, and any combinations thereof; and adding one or more ingredients having a naturally occurring copper source to provide a naturally occurring copper concentration in the pet food composition from about 7.3 ppm to about 25.0 ppm, adjusted for a dry matter basis.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 21, 2023
    Assignee: The Scoop Pet Food Manufacturing LLC
    Inventors: Philip Van Vranken, Timothy Glen Vande Giessen
  • Patent number: 11607398
    Abstract: A composition formulated from sunflower, including Helianthus annulus and methods for use of the composition for treating obesity in a subject.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: March 21, 2023
    Assignee: Vidya Herbs, Inc.
    Inventor: Kodimule Shyam Prasad
  • Patent number: 11549133
    Abstract: The disclosure relates to a preparation method of a amylodextrin and belongs to the technical field of starch chemical modification. According to the method, de-clustering and complexation effects of ultrasonic waves are used to achieve de-clustering of a starch chain and complexation of an amorphous region and an emulsifier, and then ?-amylase and pullulanase are used to achieve complex enzymolysis. Because the amorphous region and the emulsifier form a complex which is resistant to enzymolysis, the amorphous region is prevented from being destroyed. Finally, dextrins of different molecular weights are separated by a membrane separation method, so as to obtain a amylodextrin product with low polydispersity coefficient and narrow molecular weight distribution, and the starch comprehensive utilization efficiency is increased to 70% or above.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: January 10, 2023
    Assignee: Jiangnan University
    Inventors: Yaoqi Tian, Xintian Wang, Rongrong Ma, Jinling Zhan
  • Patent number: 11528929
    Abstract: A nutritional supplement composition for treatment of bladder disorders, in particular, overactive bladder (OAB) includes therapeutically effective amounts of pumpkin seed extract, nitric oxide precursor, vitamin D3, prebiotic fiber, preservative, and stabilizer.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: December 20, 2022
    Inventor: Michael Beller
  • Patent number: 11497785
    Abstract: The present invention relates to a composition for use as an oral anti-parasitic, the composition comprises one or more of an essential oil which contains gamma-terpinene, and/or carvacrol, and/or thymol, and/or terpinenol, and/or eucalyptol and/or eugenol, an essential oil of genus Cinnamomum, Eugenia, Eucalyptus or a source of saponin. It also relates to a method of preventing or treating parasitic infection in an animal, the method comprising orally administering to said animal a composition comprising one or more of an essential oil which contains gamma-terpinene, and/or carvacrol, and/or thymol, and/or terpinenol, and/or eucalyptol and/or eugenol, an essential oil of genus Cinnamomum, Eugenia, Eucalyptus or a source of saponin.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: November 15, 2022
    Assignee: MARS, INCORPORATED
    Inventors: Alexandre Feugier, Nicolas Lerouxel
  • Patent number: 11484503
    Abstract: The invention relates to an oral delivery vehicle tablet, the delivery vehicle tablet being formed by compression of a plurality of particles, wherein the oral delivery vehicle tablet comprises sugar alcohol(s) in an amount of 40 to 99.9% by weight of the delivery vehicle tablet, wherein the oral delivery vehicle tablet comprises non-direct compressible (non-DC) erythritol particles in an amount of 15-50% by weight of the delivery vehicle tablet, wherein the oral delivery vehicle tablet comprises one or more binders other than binders granulated to the sugar alcohol(s) in an amount of 0.1 to 6% by weight of the tablet, wherein the delivery vehicle tablet comprises a plurality of further sugar alcohol particles in an amount of at least 10% by weight of the delivery vehicle tablet and wherein said further sugar alcohols particles have a composition which is different from said non-DC erythritol.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: November 1, 2022
    Assignee: FERTIN PHARMA A/S
    Inventor: Helle Wittorff
  • Patent number: 11459354
    Abstract: The present invention provides improved processes for purifying liraglutide. Liraglutide is purified via two sequential RP-HPLC purifications followed by a salt-exchange step, where a pH is kept constant in the first and second purification steps. In particular, the processes utilize a halogenated solvent in a sample preparation step, which provides better solubility and an environment suitable for decarboxylation for crude liraglutide prior to a RP-HPLC purification.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: October 4, 2022
    Assignee: ScinoPharm Taiwan, Ltd.
    Inventors: Ming-Chih Wu, Hsin-Che Huang, Tsung-Yu Hsiao
  • Patent number: 11412761
    Abstract: A process for extraction of crude oil from distillers dried grain solubles and/or distillers dried grains using a solvent extraction process and producing corn distillers meal that may be used as an animal feed supplement is disclosed. The corn distillers meal may be used as a crude protein supplement for use in a livestock feed diet, poultry feed diet, aquatic feed diet or the like. The solvent extracted crude oil may be suitable for other processes, including oleochemical processing for personal care and home care products, biodiesel production, and/or renewable diesel production from hydro-treating the extracted oil to make green diesel fuel.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: August 16, 2022
    Assignee: Novita Nurtition, LLC
    Inventors: Keith Bruinsma, Donald Endres, Steven J. Furcich
  • Patent number: 11406650
    Abstract: The invention proposes a nutritional composition comprising selected oligosaccharides that reduces the abundance of Streptococcus bacteria in the gut of infants or young mammals. The infants are preferably infants in needs presenting a relatively high count of Streptococcus. Ultimately the reduction of streptococcus and the related microbiota balance affects and lowers the risk of adiposity or obesity later in life.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: August 9, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Olga Sakwinska, Bernard Berger, Irma Silva Zolezzi, Joanna Holbrook
  • Patent number: 11406121
    Abstract: A rice cooker assembly uses machine learning models to identify and classify content in grain mixtures thereby to provide better automation of the cooking process. As one example, a rice cooker has a chamber storing grains. A camera is positioned to view an interior of the chamber. The camera captures images of the contents of the chamber. From the images, the machine learning model determines whether the contents of the chamber includes one type or multiple types of grain or whether the contents of the chamber includes any inedible objects. The machine learning model further classifies the one or more types of grains and inedible objects if any. The cooking process may be controlled accordingly. The machine learning model may be resident in the rice cooker or it may be accessed via a network.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: August 9, 2022
    Assignee: MIDEA GROUP CO., LTD.
    Inventors: Dongyan Wang, Linnan Zhu, Xiaochun Li, Junyang Zhou
  • Patent number: 11399557
    Abstract: The present invention relates to low-calorie hot sauces, and more particularly, to hot sauces containing hot spices, acid-resistant thickeners and low-calorie or calorie-free saccharides.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: August 2, 2022
    Assignee: SAMYANG CORPORATION
    Inventors: A-ra Jo, Bong Chan Kim, Si Young Kim, Kyung Soon Park, Su Youn Lim, Se Ra Hong
  • Patent number: 11388913
    Abstract: Substitute fiber materials include at least one starch, at least one acid, and at least one plasticizer. The starch may be ground whole grain, the acid may be citric acid, and the plasticizer may be glycerin. The substitute materials are biodegradable and compostable. Methods involve feeding animals the substitute fiber materials as a substitute for or a supplement to natural fiber. The substitute fiber materials are at least partially digested in the animal.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: July 19, 2022
    Assignee: Purina Animal Nutrition LLC
    Inventors: Michael S. Burr, Jill A. Davidson, Catherine M. K. Bradley, Ronald R. Scott
  • Patent number: 11388914
    Abstract: A process of preparing a sterilized wet pet food product is provided, as well as a sterilized wet pet food product provided by the process. Use of the wet pet food product to feed a companion animal is also contemplated.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: July 19, 2022
    Assignee: Mars, Incorporated
    Inventors: Mathieu Mao, Christoph Hendrik Beckmann, Marinus Pannevis, Alicia Olivares, Nadine Schuetz
  • Patent number: 11382343
    Abstract: A pelleting system and method for pelletizing a cellulosic fiber into feed pellets. The pelleting system includes a mixer adapted to combine a shredded cellulosic fiber with at least one additive and a preservative to form a mixture; a pellet feeder for injecting said mixture into a conditioning chamber, the conditioning chamber adapted to apply steam to the mixture to add moisture and heat to said mixture for softening the mixture to facilitate pelletizing; and a pellet mill adapted to compress the mixture to form feed pellets. The final product may be a feed pellet having a compression ratio between about 7 L/D and about 16 L/D and containing between about 9 wt. % moisture and about 12 wt. % moisture.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: July 12, 2022
    Assignee: Project Plaid, LLC
    Inventor: Jason M. Pendleton
  • Patent number: 11378580
    Abstract: The present invention provides: a method of pretreating a serum or plasma sample for detection of a protein or a plurality of proteins of interest in a serum or plasma sample via mass spectrometry and a method of detecting such a protein or proteins, wherein proteins such as albumin present in abundance in a sample are removed in a convenient manner, thereby making it possible to collect digested peptides from the protein of interest. Specifically, the present invention provides a method of pretreating a sample for detecting proteins in a serum or plasma sample via mass spectrometry, comprising a step of adding a protease to the sample under non-denaturing conditions to digest proteins and a step of separating the obtained peptides from undigested proteins, and a method of detecting proteins, comprising subjecting the obtained peptides to mass spectrometry.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: July 5, 2022
    Assignee: Shimadzu Corporation
    Inventors: Atsuhiko Toyama, Taka-Aki Sato
  • Patent number: 11376294
    Abstract: A method for enhancing at least one of alertness, attention, concentration and memory in a person in need thereof, comprising co-administering an effective amount of mangiferin, norathyriol, or an extract comprising mangiferin or norathyriol; and caffeine to the person. The components may be co-administered in a single composition, or administered in separate compositions. The mangiferin and/or norathyriol exhibit synergistic effects on brain wave activity when co-administered with caffeine.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: July 5, 2022
    Assignee: NEKTIUM PHARMA S.L.
    Inventors: Miguel Jimenez del Rio, Julia C. Wiebe, Laura Lopez-Rios, Tanausu Vega-Morales, Ruben Perez-Machin, Alvaro Sanchez-Rodriquez, Carlos J. Mateos, Nigel Peter Gericke
  • Patent number: 11357249
    Abstract: The invention concerns synthetic nutritional formulations, particularly milk based compositions, for infants and children. The compositions are especially adapted to the age of the child, younger or older than three months. The invention further relates to administration of these compositions for promoting the healthy establishment of cognitive function in infant boys and girls and in young boys and girls up to the age of thirty-six months.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: June 14, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Carlos Antonio De Castro, Cristina Cruz-Hernandez, Frederic Destaillats, Francesca Giuffrida, Rajat Mukherjee, Sagar Thakkar
  • Patent number: 11357785
    Abstract: The present invention relates to compositions comprising 6?-sialyllactose (6?SL) and lacto-N-tetraose (LNT), for use in the reduction of nociception in an infant or in a young child. The compositions are in particular useful in reducing abdominal pain, such as pain associated with infantile colic, irritable bowel syndrome (IBS) and/or recurrent abdominal pain (RAP), and consequently also contribute to reducing the crying periods and to improving the quality of sleep and the general quality of life of the infants and young children.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: June 14, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Sami Damak, Norbert Sprenger, Francis Foata
  • Patent number: 11357252
    Abstract: Synthetic nutritional compositions for infants and young children up to the age of thirty-six months, particularly infant formulae and growing-up milks, vary according to gender and the age of the infant or young child. The compositions have been designed to ensure balanced growth and to prevent obesity in in-fancy and later in life.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: June 14, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Carlos Antonio DeCastro, Frederic Destaillats, Francesca Giuffrida, Sagar Thakkar, Rajat Mukherjee
  • Patent number: 11350651
    Abstract: A beverage containing a natural colorant and one or more components of an Indian gooseberry extract and having sufficient color photostability is described. The active component in the Indian gooseberry extract is at least one of tannic acid, chebulinic acid, chebulagic acid, and phyllemblin. The natural colorant is a carotenoid and/or an anthocyanin. When the natural colorant is beta-carotene, it is preferably provided in a form of microemulsion. The beverage further contains a preservative, such as benzoic acid, sorbic acid, and a salt thereof. A method of formulating the beverage is also described.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: June 7, 2022
    Assignee: TALKING RAIN BEVERAGE COMPANY, INC.
    Inventors: Rachel Nicole Montenegro, Kraig Allen Van Wieringen, Emma Kate Stewart, Jagriti Sharma, Erik Throndsen
  • Patent number: 11351162
    Abstract: The invention relates an oral delivery vehicle tablet containing nicotine, the delivery vehicle tablet being formed by compression of a plurality of particles, the oral delivery vehicle tablet comprising nicotine, the oral delivery vehicle tablet comprising sugar alcohol(s) in an amount of 40 to 100% by weight of the delivery vehicle tablet, wherein at least 10% by weight of the delivery vehicle tablet comprises a plurality of particles consisting of erythritol and wherein the delivery vehicle tablet comprises a plurality of further sugar alcohol particles in an amount of at least 10% by weight of the delivery vehicle tablet, wherein said further sugar alcohol particles comprise at least one sugar alcohol and wherein said further sugar alcohols particles have a composition which is different from said particles consisting of erythritol.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: June 7, 2022
    Assignee: FERTIN PHARMA A/S
    Inventors: Helle Wittorff, Heidi Ziegler Bruun, Dorthe Schackinger Boesen
  • Patent number: 11344046
    Abstract: Disclosed is a composition comprising a gluconic acid and/or one or more gluconic acid derivatives and a controlled release agent, wherein the controlled release agent allows partial, substantial, or substantially complete ruminal bypass of the composition. The composition may be used as a ruminant feed or feed supplement, particularly for increasing milk fat production in a lactating ruminant, for improving the health status of the hindgut of a ruminant, for increasing the production of butyrate in the hindgut of a ruminant, and/or for increasing somatic growth of a ruminant.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: May 31, 2022
    Assignee: NUTRECO NEDERLAND B.V.
    Inventor: John Henry Doelman
  • Patent number: 11297873
    Abstract: A nutritional composition comprises fat, protein and carbohydrate such that the fat provides from about 60 to about 90% of the total calories of the composition, the protein provides from about 10 to about 30% of the total calories of the composition, and the carbohydrate provides from about 0.1 to about 15% of the total calories of the composition, and the composition comprises from about 0.01 to about 10 wt % beta-hydroxy-beta-methylbutyrate (HMB). A method of achieving or sustaining metabolic ketosis in an individual comprises administering the nutritional composition to the individual. A method of maintaining lean body mass and muscle strength in an individual during dietary ketosis comprises administering the nutritional composition to the individual.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: April 12, 2022
    Assignee: ABBOTT LABORATORIES
    Inventors: Sean Garvey, Stephen Demichele, Roger Tyre, Eric Torgerson, Steven Hertzler
  • Patent number: 11266706
    Abstract: The present specification relates to a composition containing a tea extract with an increased specific ingredient content for prevention or alleviation of lipid metabolism disorders. The use of a preparation method and a composition according to the present specification can effectively prevent and treat lipid metabolism disorders including obesity without side effects, thereby meeting related demands and promoting the development of corresponding industries.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: March 8, 2022
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Ayoung Kim, Hyun Woo Jeong, Yong-Deog Hong, Jeong-Kee Kim
  • Patent number: 11259547
    Abstract: The present invention concerns a composition containing medium-chain fatty acids or salts or mono-, di-, triglycerides, esters or amide derivatives of medium-chain fatty acids. In a further aspect, the present invention concerns also a feed, supplemented with the composition, and a method for feeding animals, in particular calves, cattle and dairy cattle.
    Type: Grant
    Filed: October 9, 2014
    Date of Patent: March 1, 2022
    Assignee: Nutrition Sciences N.V.
    Inventors: Geert Bruggeman, Katrien Deschepper
  • Patent number: 11208376
    Abstract: The invention pertains to the use of a supplement for making metals (nutritionally) available to animals, said supplement comprising at least one compound selected from the group consisting of glutamic acid N,N-diacetic acid (GLDA), a metal complex of GLDA, a sodium salt of GLDA, a potassium salt of GLDA, methylglycine-N,N-diacetic acid (MGDA), a metal complex of MGDA, a sodium salt of MGDA, a potassium salt of MGDA, ethylenediamine N,N?-disuccinic acid (EDDS), a metal complex of EDDS, a sodium salt of EDDS, a potassium salt of EDDS, iminodisuccinic acid (IDS), a metal complex of IDS, a sodium salt of IDS, and a potassium salt of IDS.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: December 28, 2021
    Assignee: Nouryon Chemicals International B.V.
    Inventors: Carel Theo Jozef Wreesmann, Adrianus Maria Reichwein, Marcellinus Alexander Van Doorn, Javier Martin-Tereso Lopéz
  • Patent number: 11141442
    Abstract: Tributyrin and/or tributyrin derivatives are used to selectively increase the levels of Bifidobacteria in the gut. In preferred methods, the tributyrin and/or tributyrin derivatives are orally administered alone or in combination with a food item or other nutritionally acceptable carrier, and may further include Bifidobacteria. Tributyrin-enhanced Bifidobacterium strains are also contemplated that include Bifidobacteria previously cultured in tributyrin and/or tributyrin derivatives.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: October 12, 2021
    Assignee: Compound Solutions, Inc.
    Inventor: Matthew Titlow
  • Patent number: 11129804
    Abstract: This disclosure provides pharmaceutical compositions comprising amino acid entities and uses thereof. Methods for improving liver function and for treating liver diseases comprising administering an effective amount of the compositions to a subject in need thereof are also disclosed.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: September 28, 2021
    Assignee: AXCELLA HEALTH INC.
    Inventors: Michael Hamill, Raffi Afeyan, Chung-Wei Lee, Harry Luithardt, David Berry
  • Patent number: RE49810
    Abstract: Disclosed are thickener compositions composed of xanthan gum and a chelating agent, such as ascorbic acid. The chelating agent is present in an amount with respect to said xanthan such that, when said thickener composition is used to thicken a food product, at least one mineral selected from the group consisting of iron, zinc, and calcium present in said food product is relatively more bioavailable than the mineral would be in the absence of said chelating agent. The thickener composition finds particular applicability for use with baby formulas and breast milk intended for dysphagic infants. Also disclosed are baby formulas and thickened breast milk formulations, methods for preparing same, and methods for providing nutrition.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: January 23, 2024
    Assignee: Kent Precision Foods Group, Inc.
    Inventor: Douglas A. Stetzer